<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="https://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2B6</accession>
    <name>X0B2B6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658784">
        <property type="protein sequence ID" value="EXK75896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2B6"/>
    <dbReference type="HOGENOM" id="CLU_150154_0_0_1"/>
    <dbReference type="OrthoDB" id="5050412at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="104" mass="11552" checksum="ABDD2B1DA39A251D" modified="2014-05-14" version="1">MLRYDGTGFTRVEADYSKPWLPGESRPEATPGEDYSRPWFPATPADQLMVNAAARATNKNEPKGKKNTASVDSDRLKVLATEALRQAEEMTDHTTRGTPPTLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2T7</accession>
    <name>X0B2T7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_18818</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658719">
        <property type="protein sequence ID" value="EXK76440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2T7"/>
    <dbReference type="HOGENOM" id="CLU_000288_6_16_1"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001638">
        <property type="entry name" value="NACHT and WD40 domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NACHT" evidence="4">
        <location>
            <begin position="83"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="607"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="682"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="724"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="766"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="808"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="862"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="904"/>
            <end position="945"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK76440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1051" mass="117659" checksum="8737DA4151E2F694" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4G2</accession>
    <name>X0B4G2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658695">
        <property type="protein sequence ID" value="EXK76651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4G2"/>
    <dbReference type="HOGENOM" id="CLU_1786949_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="145" mass="16402" checksum="29F3E09326AF2124" modified="2014-05-14" version="1">MGNWMFEEADITASVVQPLDSSTLNDTVTRSPPHRRADSDTLVDCDFLDGALEGLETSEHARLQELTIHNSPSWRPYEDFELYGSSNWSDDLGRQFFGRTWVTLQDKEYDELTSNEDDICYCGNCEIDIHLGNREFEGQVAASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4Y3</accession>
    <name>X0B4Y3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979444">
        <property type="protein sequence ID" value="EXK76806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4Y3"/>
    <dbReference type="HOGENOM" id="CLU_1001282_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="277" mass="31566" checksum="DEC207F910CACFF1" modified="2014-05-14" version="1">MSTKDSEAASRRHYKINKTIKAWKTRDAAVKPSSPPEFTDLRPTFQTVLSENKVQPSDISKYVKLLRKAEERRAATACGETFEKMDKELIFGLFEDVGPILFQEWFTEWKSNNQLAEDATPSNYDTQLSSEQTADGLHYIRESPAPQVGGKAPRKSFNQTFVFKPWTAENESFQPAQLTSSQPDEVEHTDELGCEPPTSRVRRRTKRPQERQRSKRRCIQGPRNTQVELDDQYSSDQSEDTAPFTDDDLEACTGFCGDKDIENVFNGVSKDQVHQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5H5</accession>
    <name>X0B5H5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658615">
        <property type="protein sequence ID" value="EXK77370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5H5"/>
    <dbReference type="HOGENOM" id="CLU_1610799_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="166" mass="19016" checksum="EDB100A6DCE99A33" modified="2014-05-14" version="1">MHEHTNYVVCNRAEFGSFFEGSSQAEVLNKDFEAITVASSMNKVILDPKSFKNIAWNTQVWDEIIDWTSSYPQKEDSQQRSEDLVQQIKTDGFPHFSSLLERAMEDGTENAEIFKRRATELAEKLQGDPEARGIVDELTKTYQSHLKSYNFTLDVIQGVIDSMQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0B677</accession>
    <name>X0B677_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Gibberellin cluster-GA14-synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_17649</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979378">
        <property type="protein sequence ID" value="EXK77650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B677"/>
    <dbReference type="HOGENOM" id="CLU_022195_0_3_1"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK77650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="60182" checksum="51E8CCFB7C9B8BDC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9R0</accession>
    <name>X0B9R0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 6">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_16474</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 6"/>
    <dbReference type="EMBL" id="JH658495">
        <property type="protein sequence ID" value="EXK78890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9R0"/>
    <dbReference type="eggNOG" id="KOG0169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002738_1_0_1"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13360">
        <property type="entry name" value="PH_PLC_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037755">
        <property type="entry name" value="Plc1_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="9">
        <location>
            <begin position="697"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="816"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="599"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="636"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK78890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1010" mass="114182" checksum="91F3626770F8164C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAR3</accession>
    <name>X0BAR3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980064">
        <property type="protein sequence ID" value="EXK75589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAR3"/>
    <dbReference type="HOGENOM" id="CLU_1266942_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="218" mass="24370" checksum="CC4B7053E7BFE219" modified="2014-05-14" version="1">MPKPSLANNGSPSWSWASLVAEIEHHLVEDDIIIVRQPSLDPEFVVIRAIPATSDAFGAVKAGEFVLGCWLHQYAGVKTYRELLKTAQVYDWADTSGDVTSSDPDSPRADPFAIFDMPQPDDLWKPENSALNKNDQTASTLPQRRQTFQLAFIAYTNPFEEWNRDVKGHAEQHYLLLGSVSNCDEHAYKRVGVAVTQPGTLFAINSENGWKRQKITIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB57</accession>
    <name>X0BB57_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979619">
        <property type="protein sequence ID" value="EXK76058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB57"/>
    <dbReference type="HOGENOM" id="CLU_2996588_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="57" mass="6639" checksum="CB20FEF3A9630F43" modified="2014-05-14" version="1">MTLRCHVYRGQRSRTDTARARWGIRSSKMKRTNRGSQPGKVGPGSRSYHHQRDTRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBG8</accession>
    <name>X0BBG8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">deoxyribose-phosphate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_16226</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="JH658481">
        <property type="protein sequence ID" value="EXK79121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBG8"/>
    <dbReference type="HOGENOM" id="CLU_005767_1_1_1"/>
    <dbReference type="OrthoDB" id="3266505at2759"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="DEOXYRIBOSE-PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="DEOXYRIBOSE-PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="406"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK79121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="667" mass="74119" checksum="132B5A4DA5869ACF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD54</accession>
    <name>X0BD54_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase family 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18527</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979452">
        <property type="protein sequence ID" value="EXK76743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD54"/>
    <dbReference type="HOGENOM" id="CLU_034303_0_0_1"/>
    <dbReference type="OrthoDB" id="549336at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="47025" checksum="770FCBE39A2CFD9E" modified="2014-05-14" version="1">MCASRPASRYLTVAACTLLLLVFYQFSLLTTSNYRNPGPPFASKKVKVSVIESKGCHDEVSASYLSALGQLSECNSNVFLAAQRFGIDSIYKLIPGADNRNLVTHNEFRPQYFESEIAAEPDIVLSVTSEYDLIDAKLKPTFAHLLHNTSSILFATVHHGNEWTDDRRFQAVKPWIKAKRLRFITLSDHVTNYMTGIVKHWATKMEAHDVPISTFPPVFTIPTAPIKNEATLRFAMQGDLVVDRRPNRDYEGTFKRFAKLNSTGQAIELHVVGNGDLLKVPEEAKDRIKFHRGLPYQEFYEVLHSATAMLPAFASHEYVESKASSTIAASLIVGSPLIADDALLNAYRFLRRDDVYYRERGEDEIDVVERIAKLPKQDRLAKAEGLREKNELLTKQGGDLFRQWISESRQRLENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHZ6</accession>
    <name>X0BHZ6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14094</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHZ6"/>
    <dbReference type="HOGENOM" id="CLU_038732_9_0_1"/>
    <dbReference type="OrthoDB" id="2349068at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF34">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="352" mass="37548" checksum="3578A2BAB88737E2" modified="2014-05-14" version="1">MSSSKERRTRLLESLPWAEHPLISSAPMSGFATNELAVAVSKAGGLGQIGFTGSPGILQRELEQAKQKLHGTSIFDETSKVLPIGVGIIAFGGPASPWTQTFAKYKPAMVWLSFGTDIEFKSWAENIRAASPETKVWIQVGSVKAALQAASCSAPDAIVLQGSDAGGHGHKNGASIITLIPEALDALHEKGLSNFPIIAAGGIMDKRSVAAAIALGASGVVMGTRFLASHEIEVDDQVADECLAARDGGETTVRSRVFDDIWGHNFWPDMYDGRCLRNAMYDNVEEEGMSIQEARLALSTQNGGEGSVVRDSYTIWAGTGVGMLKKKEKAANIVKQIREETKDLMGSLTEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BID8</accession>
    <name>X0BID8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658425">
        <property type="protein sequence ID" value="EXK81606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BID8"/>
    <dbReference type="HOGENOM" id="CLU_012494_3_1_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="85"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="388" mass="42216" checksum="8DB2873750B79CEE" modified="2014-05-14" version="1">MADFHAKTQLVKESPPWMRRIAYNVQIRAIQATLTTIDWLGSFSRTSANAPNIVKTYNVRDHLPVRIFLPSSYEAGSSKALPTLFTIHGGGFCIGSSQDDDAWNRSFSDTHSVLVVALNYSKAPAAPFPTGLDDLVSLYLATLDDESLPIDKANGGRIAICGFSAGGNLSLGLSQRLLQSDHCTCHPRAAISVYGALDLSRSPEAKASTRQYKTDASLGSPRTSARDLLLNMAPLFDWSYLPDGQDLQDPLVSPGPCADPDDLPPHVFIIASELDMLAKESQDCASRLAHARGGSGIPVADSEIARCGRSEPGKPGELELEDKRFAWQETFPDGSVRWLLVPDVLHGFDSLPMRERLGGEETIKDAELKTEAYCKLLGDWLLNTVFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIR3</accession>
    <name>X0BIR3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_16971</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658527">
        <property type="protein sequence ID" value="EXK78354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIR3"/>
    <dbReference type="HOGENOM" id="CLU_027816_3_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF683">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="45"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK78354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="414" mass="45092" checksum="5E4C4DF3CD89FA9F" modified="2014-05-14" version="1">MAEDLESRLDERFYLADADKPARQEIVTQDAVFGTISKYGPNCRNIGWLGTSVLMMNAQIGLGVLSLPSAFNTLGLLPGIIGLLALAYITTWGSYELGVFKLKHPEIYGYHDAMGLVFSRIGYEFLALAFALFLVFCCASGLLSISIALNAVSIYATCTAAFAGVAAVVVFCLASIRTMGRLRWLAWIVMGCIFVALLTVTIGFGVQERPDAAPVTSGPWKSDWQLVVHPSLTEAMSAVTTMVFSLTGTPFFFAMMSDMRDPRRYQKSLFLCQGVVVATFITISIAAYAIALPGLCVSATLSAHTVSKFFFVRILRGSHHLSSNTFIHYATWFGCVGFTIVVAYLIASGIPIFDRLVSLVGTLLGTLMVFQPVGIMWLYDNWGAFKENPTTLLTLRLALVIFVIVLGTFMMIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJZ9</accession>
    <name>X0BJZ9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658503">
        <property type="protein sequence ID" value="EXK78779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJZ9"/>
    <dbReference type="HOGENOM" id="CLU_019138_0_0_1"/>
    <dbReference type="OrthoDB" id="4227485at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022198">
        <property type="entry name" value="DUF3723"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12520">
        <property type="entry name" value="DUF3723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="637" mass="72398" checksum="6125516D21A173CD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLB4</accession>
    <name>X0BLB4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16139</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979350">
        <property type="protein sequence ID" value="EXK79249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLB4"/>
    <dbReference type="eggNOG" id="ENOG502QSKG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_0_2_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="39402" checksum="9F433C9ACD983897" modified="2014-05-14" version="1">MSAAADVTQGESVPSQDMLAPTHWENTEATDNSDSDSALGDDAASSTASINSSILEYRTINGRTYHAERGDAQYWASNDNQASEALDIIHHTSTLIMDGKLFLAPVKEPSKVLDIGTGTGIWAMDFGDEFPEAEVIGTDISPIQPTWVPPNVKFEIEDFTLDWTFPPNSADFVHLRFLYGSVPDWYALYERAYQVTKPGGWIESHEGDPMGRSDDDSLKPGSAIVEWGKFFHEGGKKLGRVFTPLPDNLQEKGLKAAGFVDIQSKTIKVPVGDWPQDERLKEIGRFTTMSILSDVEGHISFMATLLEGWTQEQVHLYCAQLRRELKSKKPAHAYYLQRIVWGRKPVEGETTTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLS8</accession>
    <name>X0BLS8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetylornithine deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLS8"/>
    <dbReference type="eggNOG" id="KOG2275">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_3_0_1"/>
    <dbReference type="OrthoDB" id="3064516at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05652">
        <property type="entry name" value="M20_ArgE_DapE-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050072">
        <property type="entry name" value="Peptidase_M20A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808:SF8">
        <property type="entry name" value="PEPTIDASE M20 DIMERISATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="6">
        <location>
            <begin position="191"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="378" mass="40472" checksum="82B1C2F73C21018B" modified="2014-05-14" version="1">MKLINTILFTAAAATVFNLGSVQLPFSHESLKSSALLELHKSLVERPSITGSEKHVTDFLQTYLQDAGFTVETQSVAKNRDNILAYYNNTRKTKVLVTSHIDTVPPFWPYERRGDEIWGRGTVDAKGSVAAQIIAVQELFDKKEVNDGDVALLFVVGEETGGPGMGNVNDLGLSWESVVFGEPTELKLARGHKGGLGFTIKANGKAGHSGYPETGSNAIDSLVRGLAALQKIDLPGSKEFGNTTLNVGRIEGGVAGNVIPASAYATGGVRVAGGTPEGIKDLILQAVEESDPSLVVEFSYGIGPVPTDYDVDGFETIVLNYGTDIPRLKGSHKRYLYGPGSILEAHSAHEHLKVSDLEQAVEGYKKLISHALDQPSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BN26</accession>
    <name>X0BN26_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658405">
        <property type="protein sequence ID" value="EXK83226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BN26"/>
    <dbReference type="eggNOG" id="KOG0581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2831249_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="66" mass="7646" checksum="3A403AAD590B44B9" modified="2014-05-14" version="1">MMTELEDKVRREEGIVSRPESTLNNSSENTGQATYQQPEEETTTQGQEDTSERRPRKDKDKRSSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPQ7</accession>
    <name>X0BPQ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lysophospholipase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658444">
        <property type="protein sequence ID" value="EXK80459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPQ7"/>
    <dbReference type="HOGENOM" id="CLU_015101_4_0_1"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF85">
        <property type="entry name" value="A, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936590" description="Lysophospholipase A" evidence="2">
        <location>
            <begin position="17"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="35852" checksum="FC57C89A373BA502" modified="2014-05-14" version="1">MLVVLLSLTLAQQCFSLSLPSYRSHFNWKSTKHLIAFGDSYTFVQGTHGHPGSSFIGSYLPGQFAITPEELLSNQIVQNFSGTAEGGPNWVEYLTGCGLEEGLTSPSTCELQLWDFAFAGADVSEEFTPLHHNFTTPLVNQTQQFLTYAQPVLAKQRSFKQKHALVAIWIGINDISDSSRYNVSFPDFYDSLWDAVFTQSVQPLFDAGYHNFLFINLPPLDRTPPNVNRMNPLPNATMLDWFGKSQARHSEAFAAAHPTAKTMIFDANKFLNNVLDNPRDYGISNTTGFCPGYTNADVVTDPGKYGCVPINEYFWFNTGHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPZ9</accession>
    <name>X0BPZ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Choline monooxygenase, chloroplastic</fullName>
            <ecNumber evidence="5">1.14.15.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_14920</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the first step of the osmoprotectant glycine betaine synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>choline + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = betaine aldehyde hydrate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:17769"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15870"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.14.15.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (monooxygenase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the choline monooxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.7" evidence="5"/>
    <dbReference type="EMBL" id="JH658441">
        <property type="protein sequence ID" value="EXK80564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPZ9"/>
    <dbReference type="eggNOG" id="ENOG502RSHT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026244_1_2_1"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="UniPathway" id="UPA00529">
        <property type="reaction ID" value="UER00430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019133">
        <property type="term" value="F:choline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019285">
        <property type="term" value="P:glycine betaine biosynthetic process from choline"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00680">
        <property type="entry name" value="RHO_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03469">
        <property type="entry name" value="Rieske_RO_Alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.380.10">
        <property type="entry name" value="Naphthalene 1,2-dioxygenase Alpha Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015881">
        <property type="entry name" value="ARHD_Rieske_2Fe_2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015879">
        <property type="entry name" value="Ring_hydroxy_dOase_asu_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001663">
        <property type="entry name" value="Rng_hydr_dOase-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756">
        <property type="entry name" value="CHOLINE MONOOXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756:SF5">
        <property type="entry name" value="CHOLINE MONOOXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00848">
        <property type="entry name" value="Ring_hydroxyl_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00090">
        <property type="entry name" value="RNGDIOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00570">
        <property type="entry name" value="RING_HYDROXYL_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="14">
        <location>
            <begin position="44"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK80564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="401" mass="46397" checksum="4C037975D1126485" modified="2014-05-14" version="1">MFQFLSQSKAAPATTDVPRALPASWYREPAMYELERRAVFSKRWLLVTHKSRFNKTGDYVRYQEAGFSFFLCRDREGNLNGFHNICRHRAYPVITKDEGNAKILACQYHGWSYGLSGKLAKAPRFENMDTFDTDSNGLFKVHVYVDHRGFVWINFDGNETPVPWDADFKGADKQPRLDNFNMDDYSFDHAWYMNGNYNWKTLVDNYNECYHCSVAHPGIAATSDLKTYKVETKGGQIQHYVQDKPGKESGLDVAPTFFFPNASVTMTTKYFYLMRVVPTSATTTSMQYEVYRHKDATDEEFREIDQFFKQVESEDKDLCNAAQKNLNAGVYITGDLNSFNEKGVLYFQRLLKDAVVQHRKEEQKNGKEIWPATRIAARSGIQEEVEFCQGLCQSTNKEVEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQW4</accession>
    <name>X0BQW4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658434">
        <property type="protein sequence ID" value="EXK80869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQW4"/>
    <dbReference type="HOGENOM" id="CLU_2812455_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="67" mass="7715" checksum="353BD26C06866B09" modified="2014-05-14" version="1">MYPSQESPKKSDEKKGTLNEEHTKNYQLQDINEGQKGADMSKIMEDSKEDEQKKCGYDSFKKSTYCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRH9</accession>
    <name>X0BRH9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_11025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRH9"/>
    <dbReference type="eggNOG" id="KOG0134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_6_3_1"/>
    <dbReference type="OrthoDB" id="1663137at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04733">
        <property type="entry name" value="OYE_like_2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051799">
        <property type="entry name" value="NADH_flavin_oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656:SF5">
        <property type="entry name" value="NADH:FLAVIN OXIDOREDUCTASE_NADH OXIDASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="5">
        <location>
            <begin position="18"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK84780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="450" mass="50054" checksum="05CF76B478971F56" modified="2014-05-14" version="1">MAPRRFSTEPADASPLGQPLKFEFSGKTAKNRFMKAAMTERLSTWDPKVLEKRGVPTPELINVYRRWGEGDFGVILTGNVMIEYDQLEAAGNPIVPRDEPASGERFEAFKELATVSKKHGSLIVAQVSHPGRQVADNIQKNPISPSDVQLEGEVMGMHFAKPKPMDEQDFKNVIEGFSHAAEFLYKAGYDGIQLHGAHGYLLAQFLSPTTNKRTDKYGGSIENRSRIIFEIADAIRARVPDKSFSLSIKVNSVEFQEGGFSTDDCKVLCKQLEQHGFDFVELSGGTYQSLAFSHRRESSKKREAFFLEFAEKIIPELTKTKAYVTGGLRTVKAMNEALKTVHGIGLARPVTNEFDLPAKILKGEANSAIDTLLDEQNFGITNVAAGTQIRLVGKDKHPLDLSREDHKRIFEESMQKWGEGMSHNDDQSKYGYVDIEGVKLEPYGQAYAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRV4</accession>
    <name>X0BRV4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14337</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658428">
        <property type="protein sequence ID" value="EXK81179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRV4"/>
    <dbReference type="eggNOG" id="ENOG502QR1M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF4">
        <property type="entry name" value="CONIDIAL DEVELOPMENT PROTEIN FLUFFY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="212"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="808" mass="89513" checksum="A434E35A3F1377D1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSE2</accession>
    <name>X0BSE2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_14154</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="KI979332">
        <property type="protein sequence ID" value="EXK81404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSE2"/>
    <dbReference type="eggNOG" id="KOG0371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004962_8_1_1"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="8">
        <location>
            <begin position="133"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK81404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="328" mass="37334" checksum="BE7D3CC5408352C5" modified="2014-05-14" version="1">MDTNMEDVGRAPAEASPVLNFEPTTIPTLDGWIESLMSCKQLAEADVQRLCDKAREVLQEESNVQPVKCPVTVCGDIHGQFHDLMELFKIGGPNPDTNYLFMGDYVDRGYYSVETVTLLVALKIRYPQRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALIDNQIFCLHGGLSPSIDTLDNIRALDRIQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISEAFNHNNGLTLIARAHQLVMEGYNWSQDRNVVTIFSAPNYCYRCGNQAAIMEIDEHLKYTFLQFDPCPRAGEPMVSRRTPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTK0</accession>
    <name>X0BTK0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TIL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTK0"/>
    <dbReference type="HOGENOM" id="CLU_2757911_0_0_1"/>
    <dbReference type="OrthoDB" id="4970478at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938849" description="TIL domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="7281" checksum="0D25A7ADF6973266" modified="2014-05-14" version="1">MQFSIFSILAIATIAIAAPQSSCSNGGLFYSDPKTLEPCKSECAGGTCAFQGKCETDPNIPLLCLAKCTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV22</accession>
    <name>X0BV22_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HhH-GPD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10089</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV22"/>
    <dbReference type="eggNOG" id="KOG4161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053907_1_1_1"/>
    <dbReference type="OrthoDB" id="10265068at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045138">
        <property type="entry name" value="MeCP2/MBD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074:SF0">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN PROTEIN 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074">
        <property type="entry name" value="METHYL-CPG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="4">
        <location>
            <begin position="78"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="259"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK86040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="284" mass="33031" checksum="72D303C30F20CE66" modified="2014-05-14" version="1">MEDQTNTLVLQTHRRVTRSMVKNDVSDTKVIKVEKRKTAPRKVPTGVVLSASRIPPISKERFGLIQETVGRDLYKLLVAAVLWNRTRGSQARPVFQKLISRYPTPTHLAEACFSDLADLIRPIGLYNSRAARFIAFAKTWLEKPPNKSRRYRKLHYPLQGDGLDIGKDEVLDEDDVRQGWEVAHLPSLGPYAIDSYRIFHRDMLRGSADDWNGLNAVRGFEPEWKRVVPLDKELRAYLRWMWLKEGWIWDPETGGKIRASEERMERERNRSRSLSPEGFRVPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW44</accession>
    <name>X0BW44_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW44"/>
    <dbReference type="HOGENOM" id="CLU_2386256_0_0_1"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="94" mass="10371" checksum="967148FC50A0782C" modified="2014-05-14" version="1">MAPPIEVATHYPVLTGLNRELPVGVQTRPTAIERINRTEPKLREYKEMLEAAEGKMGNNDSGATPIADPLLLDAASVFQGQVRYQGHQVFVNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYJ6</accession>
    <name>X0BYJ6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980023">
        <property type="protein sequence ID" value="EXK75612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYJ6"/>
    <dbReference type="HOGENOM" id="CLU_101852_0_0_1"/>
    <dbReference type="OrthoDB" id="5242801at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="192" mass="21815" checksum="689A66D47B034B44" modified="2014-05-14" version="1">MTGQDNSAVLQEPDIDQLARSVMRPDALHVFANNMEKVYEFWRMLHTMTSIPNDTPDTNSFILKAFQFIENTMVGQDLPPQLCRLVHVALTNMAARFSRAIAIDRRRGRFRSRSGYRNAAIVMDLFLEAQGFIADRVHAKKQLNRRMQTSRCWTQLAKGCPLLLVVYSDAAESLVLVLPSEVSQLLTVKCQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZD1</accession>
    <name>X0BZD1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658784">
        <property type="protein sequence ID" value="EXK75897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZD1"/>
    <dbReference type="HOGENOM" id="CLU_2542678_0_0_1"/>
    <dbReference type="OrthoDB" id="10389716at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="83" mass="9372" checksum="8D04CB4E07429729" modified="2014-05-14" version="1">MPTKSENNQDQRSTGEHASTLQRTTGSYWLQRAPAFSDISPSPKQFQAINNHRKDESEGPQGLAELEEEALIYLDDELGLKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0D6</accession>
    <name>X0C0D6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WW domain-containing oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08934</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0D6"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_0_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF272">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="36307" checksum="780FD95CF1841503" modified="2014-05-14" version="1">MSRYADAHKNTSGPGDARPTALQIVRDEDLEGALTDKVFLITGTSAGIGVEVGRAIAATGARVFLAVRDLEKGKAACSSFLKPGQVDLIRLDTADMSSVRACAAEFLEKSPTLNVLINNAAIMATPTRIETKDGFEQQLATNYLGHFLLFWLLKDALLKGSTPEFNSRLVNVSSSGHHASEVIYDDFQLKAPDAYNPFKAYGQSKLAQIYMSNYIDRVYGPKGLHATSVMPGGIASNLQKHLPEAVHRDMKENPSTINFMKRPEQGAATTVLAAVGKEWEGKGGKYLENCRPSMPQPLIPGMMGYKDYIYVSEKENRTWELTLETLGLQETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1F3</accession>
    <name>X0C1F3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1F3"/>
    <dbReference type="eggNOG" id="ENOG502SI7R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057896_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35397" checksum="D6334D72063598BC" modified="2014-05-14" version="1">MARRSSKSSASRPALSSRPAGSIRIVMPSTKSAPPADPAPAVTEEDVNKINIADLTLDVPLIPLRPKRRVPKTPFHFLSLPAEVRIQIYTYFFDDVDTLLDLGPQNYKRVHKKLGLMRVCRQVHDEATFAFYSTRTFRLFPTYPGKYFKSKKPLLARLKPQQRKCVTSLELRLGPGWNAPPRGWVVNPALGLSDCVDVEHLNVFVECDPSDNIFQGWRRSDGFYEGFSRNLLTDVLEALPSVHTVQFDGWTSVKKSGDMMQGLMGVVNEAGLAIEWGPERGWTDTSVDEEDETQRVGYPEGFPHPGYEAHGLLALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4J0</accession>
    <name>X0C4J0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Regulatory P domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4J0"/>
    <dbReference type="eggNOG" id="ENOG502QQSB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031217_0_0_1"/>
    <dbReference type="OrthoDB" id="2099887at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013211">
        <property type="entry name" value="LVIVD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF1">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08309">
        <property type="entry name" value="LVIVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939100" description="Regulatory P domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="51232" checksum="433A9A8ADE23AE66" modified="2014-05-14" version="1">MKASITSLLLATLAGSAVAQTQRINTAKYNEDYLRAKSAPHAIGMGELKQRKMALHESEAAAGVFDKDRYKVLSSGTPCSDGKAGGYSCNKIDLLGFLRHQDMGSRTRVGNDVWGWTHASSGREFALLGQSDGTAFAEVHPDGSLTYVGRLPTQTVASSWRDIKVIGNYAYIGSEAAGHGLQIFDLTKLLNTDKKNPPTFSIRSDLAAHFSAFGNSHNIVANEETALIAAVGTAYDLKCRAGLWMIDVSNPKRPQDAGCVASDGYVHDAQCVIYRGPQKAFQGREICFNYNEDALTIVDISRRTMPRQLSRTTYNGATYTHQGWLTEDHKYLLLDDELDEQEKTGPAADQHTTTYIVDIQDLEYPVFRGVYKSPVRSIDHNQYVVGGVSYQANYGSGLRMVNVSSIAQDDTGALFEEIGFFDVHPEDDAVGGEAQFYGAWSVYPYFQSGNILVSSIERGLFSLRYTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4K8</accession>
    <name>X0C4K8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658586">
        <property type="protein sequence ID" value="EXK77667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4K8"/>
    <dbReference type="HOGENOM" id="CLU_047285_0_0_1"/>
    <dbReference type="OrthoDB" id="5088056at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="335" mass="38251" checksum="968B98B9894AFA57" modified="2014-05-14" version="1">MSGKLPSLVPGQASHQRDQPSRQQAAAFRKLKEKIPKSENEWQDAREVHRFATPEDVYRTVLSLVQDIQGEYMPEDLRRLIYIAVCCVDHSENEAEAYHKYRSRVHAKDDLREFTIRNYMSLVRGLVTLLDGLYLKLRHRGFEAALLFAPLNLGVLGYYKQAPDQFASCFPTIEITPEVQSSLALYLPFIITTRHPEYRYKKVCRALGTNIFNEEEYLKFVSVLQSGRPIPYVLPAPNTPDPSVASSNNKGRYDPVRDQWLPVTIPNLAGYKLFEIPESIKQIISKAGQEQDDPISRDVPGAVIFTLGWSQVHQDVVNRVIDALVSYCLRQWVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0C621</accession>
    <name>X0C621_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_09507</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C621"/>
    <dbReference type="eggNOG" id="KOG0108">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028601_0_1_1"/>
    <dbReference type="OrthoDB" id="272703at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12398">
        <property type="entry name" value="RRM_CSTF2_RNA15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.70">
        <property type="entry name" value="Transcription termination and cleavage factor, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025742">
        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026896">
        <property type="entry name" value="CSTF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038192">
        <property type="entry name" value="CSTF_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
        <property type="entry name" value="CSTF2_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14304">
        <property type="entry name" value="CSTF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="8"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="83"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK86648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="293" mass="31494" checksum="21F1B4430C438835" modified="2014-05-14" version="1">MSTRPPSRVVFVGNIPYGLTEEQITDIFSSAGKVERFRLVYDPETGRPKGFGFADYPDTDSASSAVRNLNDFEIMGRKLRVDFSNDQKSSDDDKDPGMSNYNPHVSNGAVPSYSAQPSTLPPLPAGKELPHGVSCADAISRTLETLPPPQLLDILSQMKTLASSEPQRATELLQQAPQLAYAVFQALLLMGLVSPEAIQSVVEPGAPPAAFPPAPMPNYPVASNTPPVATMPYQAPPQPYAAAPVAAPAQAAQDPDALMRAVMELPQSQIDMLPEAERQQILALRATFAGQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C660</accession>
    <name>X0C660_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_17103</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979365">
        <property type="protein sequence ID" value="EXK78207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C660"/>
    <dbReference type="eggNOG" id="KOG1357">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015846_3_0_1"/>
    <dbReference type="OrthoDB" id="2382073at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF77">
        <property type="entry name" value="8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="5">
        <location>
            <begin position="36"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK78207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="425" mass="46633" checksum="4D5AC5B7B34D1274" modified="2014-05-14" version="1">MSKPDALQHNLQLILKDRQRKGWQLEPPAPGSLTDMVDFGSNDTLSLSSSGLLGKEFLNELGKHPNFILGGRASRWGEGSTDYLFQLEQHIAQFHKADSALFFNTGYEANVAIFSTLPQPHDVVLYDSLVHASIREGMYRGRATALPFAHNDLSNLRQRLQAIKHQYERVRTGLALVFVALESFYSMDGDAAPLQAIVREVKEQLPIGNVVFVIDEAHSTGLVGPQGSGIVSYLGLEKDFSIRVHTFGKAHGASGAVVLSSRECKQVLLSCVRGLIFSTAPTFTTLAAVKAGYSILASIEGERRRDLVQSNITLFYNAVSKHAAWPSCQHLGTITIPIKPASDTLKSPIIPIIAPHGGAAALGQFLNNAKFRVLAVHFPVVPKDKERVRINLHADHTPDQILSLVDLLLKWTQSRRKDGISMSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C709</accession>
    <name>X0C709_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C709"/>
    <dbReference type="HOGENOM" id="CLU_2184054_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="111" mass="12754" checksum="85E4C6A2962CC8C7" modified="2014-05-14" version="1">MQATRSCQGRMPPEFKNPYPRKCNTTECHYQEGITAYAYITVHRFGHSAIGHLHVPPCQVADAKRPLQIRCSVDKFHNNGCQFETLLASLNNRNNHTEISTLIVLDRNFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C766</accession>
    <name>X0C766_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979355">
        <property type="protein sequence ID" value="EXK78572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C766"/>
    <dbReference type="HOGENOM" id="CLU_264523_0_0_1"/>
    <dbReference type="OrthoDB" id="5104171at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="24"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1264" mass="142549" checksum="EB8059A1EE513BC6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C798</accession>
    <name>X0C798_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07102</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C798"/>
    <dbReference type="eggNOG" id="ENOG502RS5R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053579_1_0_1"/>
    <dbReference type="OrthoDB" id="4579506at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052579">
        <property type="entry name" value="Zinc_finger_SWIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31569">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31569:SF4">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23387" checksum="A574E41B4D118D3B" modified="2014-05-14" version="1">MPNTPPPALLPPPEGIFRTFEDLMASVQRVAKDQGYGIVKLRASNYRDGKPTRYDLVCDRGGVKYNSTAKKRNPSTRKIDCPFRAKAVCEVQLGNQWRFAIQEGRHNHEPRAPSGTPGQENAPLATSIRSFTNKLDRLNHDMAQGLMRIEQRLDNIEKRMDSLEARAGGGYEPRFQAIEQRLQGMEGPRMDGMGMDDVETRLLASTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7K8</accession>
    <name>X0C7K8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_09428</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7K8"/>
    <dbReference type="eggNOG" id="KOG1110">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042860_1_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000003">
        <property type="entry name" value="membrane-associated progesterone receptor component 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF72">
        <property type="entry name" value="NEUDESIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="7">
        <location>
            <begin position="59"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK87163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="171" mass="18993" checksum="F42924542E37B421" modified="2014-05-14" version="1">MEHVEQHMAQQASQETASLFTPLNLILLSAVLYTTYSMLRSSPPPSLPRDAPSTVFKTYTPHTLLPFNGEEDRPVFLAVRGRVFDVSPGRNFYGPGGPYSNFAGRDASRGLACGSFDEDMLTKDLDGPLDKLEGLDAEQMEALQGWEERFLEKYNVVGKLVSVQDYEAQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8F8</accession>
    <name>X0C8F8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8F8"/>
    <dbReference type="eggNOG" id="ENOG502SR70">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057358_1_0_1"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="25"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK90416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="272" mass="30662" checksum="70B753D8C9315803" modified="2014-05-14" version="1">MASPEATEAEQELFFVSLNQDKPITVILLHGLLNSHLEWSYVIPYLSDYHIIAPDISGHSQSRNILPANISSSAERVAVLIRRHAHGGRAHVVGLSMGAFITLRISRQHPELVLSAIVTAGHPMEGHWAWVARYPSITYYAMLVLLELVPTWLYMLVAVKGRGMRRHEELLEEMRHNRRWEVIRAVDTGLLELKWEDIRMLPVKTLAIAAEGIDDAEAVRRMGREMPVEGSLGAVVRGAVHTWNLQKPKLFSDVIRAWIEQSALPASLEILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8Z2</accession>
    <name>X0C8Z2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C-1-tetrahydrofolate synthase, cytoplasmic</fullName>
            <ecNumber evidence="8">1.5.1.5</ecNumber>
            <ecNumber evidence="7">3.5.4.9</ecNumber>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">FOQG_06827</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">54005</strain>
        </source>
    </reference>
    <reference evidence="23" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>(6S)-5,6,7,8-tetrahydrofolate + formate + ATP = (6R)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="8"/>
    <dbReference type="EC" id="3.5.4.9" evidence="7"/>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8Z2"/>
    <dbReference type="eggNOG" id="KOG4230">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003601_2_0_1"/>
    <dbReference type="OrthoDB" id="5126881at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009257">
        <property type="term" value="P:10-formyltetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046655">
        <property type="term" value="P:folic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000006">
        <property type="entry name" value="Bifunctional protein FolD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000245">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001123">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000005">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.770:FF:000001">
        <property type="entry name" value="Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.410.10:FF:000001">
        <property type="entry name" value="Putative formate--tetrahydrofolate ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.410.10">
        <property type="entry name" value="Formyltetrahydrofolate synthetase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF5">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 23" id="KW-0436">Ligase</keyword>
    <keyword evidence="19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="17" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="21">
        <location>
            <begin position="175"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="22">
        <location>
            <begin position="312"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00017592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EXK90606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1108" mass="119660" checksum="A21BE0BFE77CDD1D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C975</accession>
    <name>X0C975_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">hydroxyacid-oxoacid transhydrogenase</fullName>
            <ecNumber evidence="4">1.1.99.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_08661</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate</text>
            <dbReference type="Rhea" id="RHEA:23048"/>
            <dbReference type="ChEBI" id="CHEBI:11047"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="EC" id="1.1.99.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:24734"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16724"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="EC" id="1.1.99.24"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.24" evidence="4"/>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C975"/>
    <dbReference type="eggNOG" id="KOG3857">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007207_0_7_1"/>
    <dbReference type="OrthoDB" id="339764at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047988">
        <property type="term" value="F:hydroxyacid-oxoacid transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08190">
        <property type="entry name" value="HOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1970:FF:000009">
        <property type="entry name" value="Fe-containing alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1090.10:FF:000003">
        <property type="entry name" value="Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042157">
        <property type="entry name" value="HOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF83">
        <property type="entry name" value="HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="9">
        <location>
            <begin position="75"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="10">
        <location>
            <begin position="297"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK87758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="495" mass="53381" checksum="8FD61B5685E7DFE5" modified="2014-05-14" version="1">MVPSVRVVPNAAKRATSLLRTIQYTHPPSCPCHSNPGYHQSPPTFTPSKHAHQRKYATPTSHPGQKEYAFEMAASSIRFGPGVTQEVGMDLKNMGAKRVCVVTDENVNKLDAMRQVRESLAREGIPYEVYDKVRVEPKDSSIKDAIAWARPYAPDAFLAVGGGSVMDTAKLMNLYTAYPDADFLDFVNAPLGKGRPVDKKLTPLIAVPTTAGTGSETTGTAIFDLVSKRAKTGVAHRNLKPTLGICDPLNTRTMPAAVKAASGLDVLCHSLESWTAIPYNERTPRPTNPILRPAYQGANPISDVFSFHALRSTVKYLPRSVKNPDDLEAQSEMLLASTLAGVGFGNAGVHLCHGMSYPISGQNPGYRHDGYEVEAPLIPHGVSVAVSAPAVFRFTAASNPDRHLAAAEAFGVDISNVKRESAGEVLAEAITKFLAELGDQPKGLKELGFGSEHIEALVEGTIPQARVLMLAPGLSTQLEAEKDQLRRLFENAMTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C989</accession>
    <name>X0C989_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C989"/>
    <dbReference type="eggNOG" id="ENOG502R7K3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030655_0_0_1"/>
    <dbReference type="OrthoDB" id="3257981at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936235" evidence="1">
        <location>
            <begin position="25"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="548" mass="59903" checksum="B097E59566325007" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9S4</accession>
    <name>X0C9S4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658471">
        <property type="protein sequence ID" value="EXK79442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9S4"/>
    <dbReference type="HOGENOM" id="CLU_219514_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="40" mass="4594" checksum="47310D136759B989" modified="2014-05-14" version="1">MELEKEGEDVVMRQKNTESFIAHLQKHAKGEQALDHDDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CA80</accession>
    <name>X0CA80_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_15838</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979345">
        <property type="protein sequence ID" value="EXK79597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CA80"/>
    <dbReference type="eggNOG" id="ENOG502QQJW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026244_1_2_1"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03469">
        <property type="entry name" value="Rieske_RO_Alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.380.10">
        <property type="entry name" value="Naphthalene 1,2-dioxygenase Alpha Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015881">
        <property type="entry name" value="ARHD_Rieske_2Fe_2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001663">
        <property type="entry name" value="Rng_hydr_dOase-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756">
        <property type="entry name" value="CHOLINE MONOOXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756:SF5">
        <property type="entry name" value="CHOLINE MONOOXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00090">
        <property type="entry name" value="RNGDIOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00570">
        <property type="entry name" value="RING_HYDROXYL_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937473" description="Rieske domain-containing protein" evidence="6">
        <location>
            <begin position="26"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="7">
        <location>
            <begin position="83"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="391" mass="44286" checksum="28B9957178BC1F93" modified="2014-05-14" version="1">MLTLGTLIFFAIAAAIALIAKKTLSKPQKENLISRAIPAAPPLTQPLPSTWYKSDDIYELERRAIFSKKWILLTHKMRFDQTGAWVRYAEAGFDFFLIRNAEGIIRGFHNICRHRAFPVVVKDNGQNNVLSCKYHGWSYGMNGQLAKAPLYQDLPGFDRSKNGLFPLHTHVDAKGFVWINMDAKAVPENPWSEDLSQSANHGSFNFDDYKFDHVKQDSSSFNWKTLADKSCTGSNIDNFENTAEKKSVVNDFFFPNASMTISPHFFFLLRCVPTSATKSQLQYEVYRHKSASESDFKKVEEILQQTASEQEAPAEKNLRAGVLVDQTPLQFQNQVYQLVEHHRKLEGVAGREIRPAQQILDKSATKTEQDESLYSSCSGLSCGKIAKDLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAW9</accession>
    <name>X0CAW9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAW9"/>
    <dbReference type="eggNOG" id="ENOG502S8AT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041452_0_0_1"/>
    <dbReference type="OrthoDB" id="4034134at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038872">
        <property type="entry name" value="Put_GTT3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41807">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41807:SF1">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="341" mass="37268" checksum="F8DC9CA423A03DF6" modified="2014-05-14" version="1">MSNHRYNSWLKTKKKGELENLAESVGLSDIDGYKKDDLGVALDNYLTENSTRFLANPELAGYFNSRSKAQGSPIKREVNREDALKVVRRRTSKAVEEVTPESDDASSPQATSTALVETPGRALSEVASRIALPATPADVALAVDRSTSIVRQRVSSLYEESGITEVSHATRDTLSTVTSILFCVAGWELWNVRREILSNVYAFTIPAISTLGTSDYPVYVPDMFLLLTSSFWSPALTWILTSVIIPSFAGYFFNLSATSPPPSRGRPRPSHADYVVDPLTFSIVKALVSFVVYGQGVNFGGFLNDLSIMRLENAIYGGYKGILTGTAVTAVVSIYDAVLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCC7</accession>
    <name>X0CCC7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Translationally-controlled tumor protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_06028</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TCTP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCC7"/>
    <dbReference type="eggNOG" id="KOG1727">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095877_0_0_1"/>
    <dbReference type="OrthoDB" id="10248936at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.150.10:FF:000002">
        <property type="entry name" value="Translationally-controlled tumor protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.10">
        <property type="entry name" value="Metal Binding Protein, Guanine Nucleotide Exchange Factor, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011323">
        <property type="entry name" value="Mss4/transl-control_tumour"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034737">
        <property type="entry name" value="TCTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018103">
        <property type="entry name" value="Translation_control_tumour_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018105">
        <property type="entry name" value="Translational_control_tumour_p"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11991">
        <property type="entry name" value="TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11991:SF0">
        <property type="entry name" value="TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00838">
        <property type="entry name" value="TCTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01653">
        <property type="entry name" value="TCTPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01002">
        <property type="entry name" value="TCTP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51797">
        <property type="entry name" value="TCTP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TCTP" evidence="3">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK92070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="170" mass="18885" checksum="35C14624E5D7B961" modified="2014-05-14" version="1">MLIYKDILTGDELISDSYDLKEVDGIVYEADCAMIEEGGLNVDIGANASAEEAAEDVDDQVVKVNNIVSSFRLQETSFDKKSYLTYLKGYMKAVKAALQEKGAPAEEITAFEKGAQNYVKNVVLAKFKDFEFLTGESMNPDGMVVLLNYREDGVTPYITVWKHGLTEMKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCP6</accession>
    <name>X0CCP6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658445">
        <property type="protein sequence ID" value="EXK80437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCP6"/>
    <dbReference type="HOGENOM" id="CLU_2454787_0_0_1"/>
    <dbReference type="OrthoDB" id="3065412at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="9411" checksum="2861EB28BD197C2E" modified="2014-05-14" version="1">MGFPAQLYLAWCRRFQRCAATCTEAVIEGVGSKTTDLGCRCSDLGSVAAKMTPCIALKGNCDFDDVPNDTDLTAGLPRTRLGSVKGGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCX2</accession>
    <name>X0CCX2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7053 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCX2"/>
    <dbReference type="eggNOG" id="ENOG502SUGN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090750_0_0_1"/>
    <dbReference type="OrthoDB" id="4276610at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055481">
        <property type="entry name" value="DUF7053"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117:SF1">
        <property type="entry name" value="DUF3074 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23155">
        <property type="entry name" value="DUF7053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7053" evidence="2">
        <location>
            <begin position="3"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="197" mass="21356" checksum="32E36631445105F7" modified="2014-05-14" version="1">MRSTQLLSISVPIPGTLPPSAVVAALQAVDPFVAHHRTVTSLEEVQADPADTADDPFFGPFDDSFRAFQMQELVNLAPGLGKTISYKAIFQIIPDGLRSRAKAPVGVVVRAQWMVRQQQHGRSPSGPISPAGSDSTASGSTATAEGDEFELHEQVLLECNSLLMPFITESCVAVHREICENFMAKTFKDYFGTSPMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD35</accession>
    <name>X0CD35_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658441">
        <property type="protein sequence ID" value="EXK80572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD35"/>
    <dbReference type="HOGENOM" id="CLU_019524_2_1_1"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF11">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="457" mass="51200" checksum="C8B356BB824DB1B5" modified="2014-05-14" version="1">MPGTPSGRGCDGCRRQKKKCDQAKPTCGRCKRVGVPCVGNGVKRWKFHSFQNDDQSLIKRRPSNEQTQLSSSLVHILQTEDARFDIRAFGGKLIPEIVAQIGCSPALDSCVNAMVSLYKSHRCQESRIDALTRYGEALTATRNAILDPKEKIIMKMQVVSIMFVCHYWVDRKSIEQHREVISVLFREAVMKNQLDDLGDYMVGLSQLAVMASFLNPQFELGPWFWEACETIGTPRPVKYHQGSFLSLESGTMGELSILMRSPKKNLRQLRCIYDVMQFEMPKVRQLLALATISTAAPNAPAMSTRVCSSYRVAYGILLAMTAVIGHTLRIWDTDLTLVGNSHDCVDECIALVEQCESARPYGANFVPDFLTMVWAAATDGYRNDEMAEYLVDYEKDSIGADFMGQAMSIRERLFAMEARETAKEVKLVLDPALESLVKRPVVSVQEIQPAVSECIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEA3</accession>
    <name>X0CEA3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_05642</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEA3"/>
    <dbReference type="eggNOG" id="ENOG502QTGV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024810_0_1_1"/>
    <dbReference type="OrthoDB" id="18453at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05462">
        <property type="entry name" value="Dicty_CAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="6">
        <location>
            <begin position="21"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK92531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="470" mass="53308" checksum="F995F8151E5B7331" modified="2014-05-14" version="1">MEGHPEHHRGPTFSPEHIEILITIERVGAGCSMIAIILVLLTFGLFKKLRTTPNLFLVFASIANAGASVASMIGYDGLERGEGSHLCQAQAFIFEWFMQSDPWWSLAMAINVFLVFFCNADPRMFRKYAWLYCMICFGGPFIPAVVLISIRNSPEGLIFGDATLWCWIGTDWSLVRLYAYYIPIWIFSFLSIMIYIAVGYHVFHTRNQIRHMVMDVIGNAEKNDHIPYSSSEHRGSSEANLTPRQDFYGTAVTEVQITREDPRQVIQQEPTLPSPPLAAMPPRIQSWVLPSSFEHIEPSTSSRAQRFETLCTSDSSRQPPSSVMTKLRAVKSNASMKLRQFDPVKMAYLRTSFIFGLAVLITWIPSSANRLYSLTHHDRISFPLSVASGCVLPLQGVWNAVIYFTTSWKTFNEEMRVLRFKWFGGAEECTNGVRLNSRLGSSKGSYRNTFERTRQLRAYSVEDAEKPVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEN0</accession>
    <name>X0CEN0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrogen regulatory protein areA GATA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEN0"/>
    <dbReference type="eggNOG" id="ENOG502QSII">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020417_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052292">
        <property type="entry name" value="Glucose_repression_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051:SF1">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="520"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="584" mass="64805" checksum="2750E7EF7C8819D8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFJ1</accession>
    <name>X0CFJ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcriptional activator of proteases prtT</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Zn(2)-C6 zinc finger-containing protein prtT</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_14144</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the prtT family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979332">
        <property type="protein sequence ID" value="EXK81387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFJ1"/>
    <dbReference type="eggNOG" id="ENOG502QU5T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027523_0_0_1"/>
    <dbReference type="OrthoDB" id="2595934at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF34">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR OF PROTEASES PRTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="12">
        <location>
            <begin position="40"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK81387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="634" mass="71045" checksum="61BDCB5734A637F5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFU7</accession>
    <name>X0CFU7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PQ loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFU7"/>
    <dbReference type="eggNOG" id="KOG2913">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040201_1_0_1"/>
    <dbReference type="OrthoDB" id="407617at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF37">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK93265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30268" checksum="E89ADD41DC4C0A1C" modified="2014-05-14" version="1">MDVPVAANILGTLGAVCWSIQLIPQIIVNYRRHNATGLQPSMMMLWAWAGVPLGVYNIVKEFNIALRIQPQILTLLSLVTWIQCYYYERKWSVYRSLLVVVPIAAVMGGIQASLIIALRIAKSRSLEWPLILMASLSAALLAAGVLTHYWDIWKHRTVRGISFLFVAIDAAGDVFSLVSVFFQPELDVLGIVIYATEFVLWCGVFACGGYYNLLPWVRKRFGSESKRVEGEESAGDGVMMNENISSSSVFRTVSGNGEGVRARNAHHGSQDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CG82</accession>
    <name>X0CG82_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CG82"/>
    <dbReference type="HOGENOM" id="CLU_1865192_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="137" mass="15436" checksum="14B93F121DABF3C2" modified="2014-05-14" version="1">MTSLSTGTVHSIIPCMLQPKSRYAANEVKRKERNHRSSLKLTVPGESSNDTALVCCILLLYLLHYSADFLTVFGLASRQSRNQCFLSPDLRTFSRSRLRELVVEDSMSMEACRARDATSFLPGQHREAKACLSSRYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CG99</accession>
    <name>X0CG99_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658424">
        <property type="protein sequence ID" value="EXK81647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CG99"/>
    <dbReference type="eggNOG" id="ENOG502SHAD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064039_1_0_1"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052358">
        <property type="entry name" value="Aro_Compnd_Degr_Hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563:SF2">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="20"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="315" mass="35951" checksum="61DB6917EBF22EE0" modified="2014-05-14" version="1">MATQVLTKSTKAELFPNGGWDTHHHIFEPSTFSYSPSRHLTPPAATVQSFKTFRQKLGITNSVLTHGLSYGDDCTSLKTFVTQLGKSSTSGVGVIDPENTTDDEIRDMQAAGICGLRVNLYHYNAMEDVELQKKTLRAYLGRVTRLSLPWSLTMTTIRTDFWDTLETFVREEVAPTGRPLITDHFGLLKAPSMLPAQYRQDPTQQPGFAPILRLVKDGLLYVKLSAPYRVSEQSPHYSDLKFLVRALVEANPRQVIWGSDWPHTPRMKVRSHEEAMKETPFLEVDDEAWLWSLREWLSDQEWHMLMVDNPKRLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGN8</accession>
    <name>X0CGN8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_13824</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH658422">
        <property type="protein sequence ID" value="EXK81752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGN8"/>
    <dbReference type="HOGENOM" id="CLU_000288_144_2_1"/>
    <dbReference type="OrthoDB" id="5103233at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="6">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="55"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK81752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="384" mass="43559" checksum="26912A66A34CBC0E" modified="2014-05-14" version="1">MHQIMVLELTHPDGPSYSSGSVPWTEDESGVPELPKESDRVDGFLPCHYFDYMAGTSTGGLNSIMLGRVRMTVDRAIDNFIDFGNSVFGHLQLFHVTSAYFRPRAKYSAVKACQAFKRIVKSRFPSTLSEVPSLVTFCPWATFVMDGGCTQTMAISYRVDDNVEKAHIWRSYDYPDSNTCLDRSAEIWEVAMATSATPGYFNPIKINGATYIDGSLVANNPSSRALREVSSIHSKAPVVFVNIGTGRQVGTNVIFRSDAKWRDLPWSERLQHPNRLFQYTTTEFYAETETKEWLELAERMGLEKAYRLSVEGDLQTIPYDDWRPAGTGKKTLQEITDFTEEYLRKDEVRDIINSIAHEAVRIRRARAITERWETFAKGYASDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHJ4</accession>
    <name>X0CHJ4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHJ4"/>
    <dbReference type="HOGENOM" id="CLU_2372864_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="109" mass="12167" checksum="96C819DD4710FF0F" modified="2014-05-14" version="1">MVPCRFCGTEYIKSMIKGHQDRCPGKCTNCKDARDDEGQEIVCFHPPSTSREPCKRCAEMGDDLDRECDGSWRRPKHRGGKTEDDGDVEDNEGSKHGGKGAEEDEDSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHW9</accession>
    <name>X0CHW9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07222</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="2"/>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHW9"/>
    <dbReference type="HOGENOM" id="CLU_031404_4_0_1"/>
    <dbReference type="OrthoDB" id="445695at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01301">
        <property type="entry name" value="rDP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK90434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="489" mass="54841" checksum="41E7708A18233DAD" modified="2014-05-14" version="1">MADSSPTVTSPPRRNSQQANTPQSTTPTNNNRDGALVLHANSSATAWWSRFRYPVITAGIVLLLSPFTFLWPGQESIDPTNYAERTKRILKTTPLIDGHNDLPFMLRLELKNRIYDERFDFNNRLLGHTDLQRLRQGMVGGQFWSVYVDCDEQQKHFEDPSWIVRDTLEQIDVTRRFIREHPKDLEYCDTAACARKAFKAGRIACMIGIEGGHQVGGSIASLRQMYELGARYMTITHNCDNAFAMAASTVASGTADSGLAKLGKVAIKEMNRLGMMVDLSHVSHQTMRDVLSIARAPVIFSHSGAYAIEPHLRNVPDDVLRQVKHNGGIVMAVFLNRFLNMKHPEQASIHDVADHIFHIAEVCGWTCVGIGADFFGMSNVPIGLEDVSKYPSLMEVLMQRGATDEQIRLLAGENILRVWGNIEKSAKEIQATGEKPVEEEYERREWHKGFSTDPYMLRGGLEEALKNGAKIEEDVFDLDAEGRPKILST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJU4</accession>
    <name>X0CJU4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenylosuccinate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJU4"/>
    <dbReference type="eggNOG" id="KOG2700">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132748_0_0_1"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172:SF1">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="19348" checksum="90856E61A9A44BD5" modified="2014-05-14" version="1">MQCSLRTNTYQTSLTAKYCNPQMAQLFSQRSRHLQWRRLWLLLVGLRKSLAITTDALEQMKQHLEVTDQDFETARAEELIRRHDVMAHVHAFGAVAPAAASIMHYGATSCFVTDNTKLILMRNALDLLLPGLPSQGYLKSMQATTTLAYTHLQPAQLITGTRVLIMLYLASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CK76</accession>
    <name>X0CK76_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_04613</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CK76"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053582_1_0_1"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000060">
        <property type="entry name" value="zinc finger protein 436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000176">
        <property type="entry name" value="zinc finger protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="273"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK94596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="309" mass="33790" checksum="CEBA4827C9FBB8F0" modified="2014-05-14" version="1">MHTAAASFMPNQYNQQETHFFTRRDQYQPPSPPMEEQKCSLPSISNLLGLADAGSPTSESSPTSRQHSPRFEVPPPSHGHSRAGSEWAKSSHRGLPPTPPMSTDASFEGYSSPTRKPSNQAYPGSAPRTYYYETTPPLEADAQRQASVTAIPRATPPATAPYPQQAHPTVYANPAPVGAYYPAAQVPPAVQPQEMNPYYQRPLPQAYPPPVSMPAPAPSGANPWQHHHYLNPTGAAAFPQSQDRYICPTCNKAFSRPSSLRIHSHSHTGEKPFKCPHAGCGKAFSVRSNMKRHERGCHSFEFNGSVIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKB6</accession>
    <name>X0CKB6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF803 domain membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03667</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKB6"/>
    <dbReference type="eggNOG" id="KOG2922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012349_0_0_1"/>
    <dbReference type="OrthoDB" id="6428174at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF85">
        <property type="entry name" value="DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G15880)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="361"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK94880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="43012" checksum="8D612D58DC8020A4" modified="2014-05-14" version="1">MIEDKYIGLALAMTSALAIGTSFVITKKGLIQAEERHGFEGDGFVYLRNPLWWAGIATLGLGEVCNFAAYAFAPAILVTPLGALSVLIGAVLGSYFLNEELGTLGKLGSAICLIGAVIIVLHAPPDEEIETVDEILHYAIQPGFLLYAFAVVAFAVFMIYKIAPVYGRRNALIYLSICSTVGSISVMSVKAFGIALKLTFAGHNQFSHPSTYVFMILTAVCIVTQMNYFNKALASFPTNIVNPLYYVTFTTATLCASFILFSGFNTNDPVNTLSLLCGFLVTFTGVYLLNLSRGDPHGQRLTAGRGGSDATGTDMVSGLQTRLSMQARRSGDPSRHSMSSQRGDREGLIRAYDEEEAAGFALTDLASDSDEDVRHANGNGKASYDENIELDNRHKSGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKC7</accession>
    <name>X0CKC7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional coactivator HFI1/ADA1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_06702</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKC7"/>
    <dbReference type="OrthoDB" id="10264870at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024738">
        <property type="entry name" value="Hfi1/Tada1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12767">
        <property type="entry name" value="SAGA-Tad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK91264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="464" mass="50918" checksum="05F7A18876F76605" modified="2014-05-14" version="1">MPDIDPAALSRPSVSLSTPILSNKTLAGTISGAPKIAKSSQIIPARIDLEPLYTALKAAIGNEKWAIYKESTTEFLIGRLNQTEYSERIDPILAGPGDKEHLHNNLIAAIYGNVTREMPDQGLAPWVSANDKPAATTGTKPVSGDATERRLKGDVMQLPTRDRRRIKDLVQNDVSVPMPPRIQLLTSNKWDPHESISNIFADTRRKLSTVTDATPTVGGINNMNFDLEIRKRYAQPLAVESGEFPDINMISGRMLPSCYEAGLVNGHTVDAPQFLSVAVETFIKEVLTQVFSRTRSNGPGESGSAGFGVGTTWIQTHKYKRQLEYEEEAAIRGEISRDKSGLLPIESRAASERGPLGMSDLRLSLEMADTGMAQFPVLMTQVIYGYREGELENWDDYTWVCDQPPEAYTDEKHDSEANGGHVFELANGYPDAMDIDTEAWWEGAESQDADMLDGILDSCLAAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKS8</accession>
    <name>X0CKS8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Catechol 1,2-dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12499</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658405">
        <property type="protein sequence ID" value="EXK83147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKS8"/>
    <dbReference type="eggNOG" id="ENOG502SMA8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046727_1_1_1"/>
    <dbReference type="OrthoDB" id="5238185at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018576">
        <property type="term" value="F:catechol 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009712">
        <property type="term" value="P:catechol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03461">
        <property type="entry name" value="1_2-HQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039390">
        <property type="entry name" value="1_2-HQD/HQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF5">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASE PRCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="8">
        <location>
            <begin position="35"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="7">
        <location>
            <begin position="118"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK83147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35784" checksum="5DC15872481C3473" modified="2014-05-14" version="1">MASNGTNGTNGATAQSKFDPNFTDHVIGLMSPETDPRQRVILTSLIRHMHDFCREVELTQDEWIIGVNYINSLGQAYKKNRNETWRVCDILGIESLVDEINHKVVTEGGKAPTSSSILGPFWSPETPFRDLGASVVQDMPKDGQLTFFHGVIRDVDTGKGIPNAVFDMWQASTNGKYDAHDPENQSRHNLRGKFRTDADGKFWFYCLKPTEYAIDTSGPSAELLKIMGRHPYRPAHIHIMVTHDDYLGVTAQLYPNDDPYLETDTACAVKDDLLLDFKPVKDEPKGAVLDVEYNVNLASKKYKPDNTMLMQNANQDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLS9</accession>
    <name>X0CLS9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_12206</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLS9"/>
    <dbReference type="HOGENOM" id="CLU_004835_3_0_1"/>
    <dbReference type="OrthoDB" id="4685598at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="12"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK83507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="615" mass="69075" checksum="1E70F887277E2011" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLU9</accession>
    <name>X0CLU9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLU9"/>
    <dbReference type="HOGENOM" id="CLU_012494_6_3_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="84"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="319" mass="34793" checksum="0BDE35E8CBBA431E" modified="2014-05-14" version="1">MSESIIREPGLATIHPEWEAFEKQLPVPPLLGTPQQLRQLKFPKANTPPVGFSIREVEVPGYQGATNQLRLYTPDDSSEPLPVIIYVHGGGWTMGDLDSEDKVCRTMCNSAGVIVISVDYRKAPENPFPIGLEDVWQGVLWVFNHIETLGGASDKIIIGGLSAGGNIAAVLAQRARSVGNIAFRGQILRVPLVVHTDTLPREFDFSSYTENAIAPILPAAAVTQCLGYYGAPPEDIRISPLLAKDHSGLPPAYIQVAGADPLRDDGFAYAERLQKAGIPVRLSVYAGFPHAFMNFPLRSAMKSDEDLIKAIKWILEIQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLZ4</accession>
    <name>X0CLZ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLZ4"/>
    <dbReference type="eggNOG" id="ENOG502S90D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096188_0_1_1"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02231">
        <property type="entry name" value="cupin_BLL6423-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047142">
        <property type="entry name" value="OryJ/VirC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156:SF3">
        <property type="entry name" value="CUPIN 2 CONSERVED BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156">
        <property type="entry name" value="SLR2101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="87"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="183" mass="20106" checksum="1CFE14767E42EB07" modified="2014-05-14" version="1">MALNGKLRQTQRIITTHNDEGKAIIDTSINSDAPFYALPNGEAHFALGYATKEFPAKLTNNADVESYQGFLTNQPGLSISTGTILRYVDMCPGHVSPMHRTVSLDYGVVLEGEVELILDSGDKKVLKRGDVCVQRATMHAWRNTSETEWARMLYVLLPSTKPDVGGKELGEDYGNMEGVKASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CML3</accession>
    <name>X0CML3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CML3"/>
    <dbReference type="eggNOG" id="ENOG502SC13">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060131_6_5_1"/>
    <dbReference type="OrthoDB" id="2744543at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="237" mass="26975" checksum="A702AFFD892C718A" modified="2014-05-14" version="1">MSSITIRPATIDDSDSIANIHYEALQFYHDFYAAFFQLHPRDLIPLATRNALQNPGQQHFLVAEQAGKTVGFVRYKEIFKDKKPNSNAKPTASVWTVKKHMEELWAWFNERSEEIDASKEKAVDGKDHIEVMHLMVHPDHQRKGIGGLLLQSVTEKADTANVPTLIVSSVEGHGLYRKHGFESLGTWTVDNEEWAHKIAEHEKAIGYTDGVIDIEDKYRGIREVEDSMIRQPSIRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN46</accession>
    <name>X0CN46_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_11919</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN46"/>
    <dbReference type="eggNOG" id="ENOG502RSJA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019101_0_1_1"/>
    <dbReference type="OrthoDB" id="2988756at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF2">
        <property type="entry name" value="SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="38"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK83972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="385" mass="42218" checksum="CE3323A14F91C347" modified="2014-05-14" version="1">MRRFFVSLFVSAAMGSATSFAAEAFTLLSIGILVIGLRTFARIRQVGVRNFEADDYLMLVAIIPYTIETALAYTVGAKFHGLTNSGMTDEERKALSPNSEEYGWRVGGSKIQIAGWIMYATVLWVIKSALCAFYFRLTAGLTGYKTRIYIGFGFIASTYIAIVCCILFSCQPFNRLWQIYPNPGNFCHPALSKLYIFIIVSLNIITDVYLLAIPIPMLWGARIPKVKKYGLLVLFSGAVFVMVAGLLRCILILKNPKTGPEEGASWAVRESFVAVVTANLPSTWGWMRQKLKPIFGSLLSSNNVSSKYKGGPEPGSIMLADGNGSNWKRSNGRSIRSTTGLGSVNDRNVYIHGGGGEASSDEIIPSMPGITKEVEFTVEESDARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQV7</accession>
    <name>X0CQV7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQV7"/>
    <dbReference type="HOGENOM" id="CLU_2210135_0_0_1"/>
    <dbReference type="OrthoDB" id="10283804at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="107" mass="11947" checksum="F6A490A2DA5FC2A9" modified="2014-05-14" version="1">MVNGTVGSELWTCRRRLCLCLWGGSLPKGGRSVRGTPVHLDSSRRGEGETTVLAVLDQGVEGIGYSRTEQDQSSSEDKNRSRVDSRENYEERKQRQSKIGKCGCVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSD9</accession>
    <name>X0CSD9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSD9"/>
    <dbReference type="eggNOG" id="ENOG502SUTN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081631_2_0_1"/>
    <dbReference type="OrthoDB" id="3830579at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="28528" checksum="127A615B1B045240" modified="2014-05-14" version="1">MASKIQNVTEFSYVTLNEGVNVFDESAAAKTYQNVLETALKQPGARRVYTGVEVENPSTLWLFLDWETLEDHENYPKTADHGPIIESLKPIVDFSKSINKHVTLTPFPPEDVLNKDCSPVTEVLLAFFPSDYDVASRATATRRLEEFTGVALKTSRDWRGISYGWSVENDVPVRGDESKTGSMLAAFIGWPSIEAHQKFRETDDFKKNIGLLREIPGLVKLAAFHVSCVSKEAEGLTERDAEKAHEHTHDHGGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSU7</accession>
    <name>X0CSU7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Vacuolar aminopeptidase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_02470</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M18 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSU7"/>
    <dbReference type="eggNOG" id="KOG2596">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019532_3_0_1"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.250.10:FF:000001">
        <property type="entry name" value="Aspartyl aminopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF4">
        <property type="entry name" value="VACUOLAR AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK97191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="60337" checksum="E5A39713DF6A2BF1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU82</accession>
    <name>X0CU82_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU82"/>
    <dbReference type="eggNOG" id="ENOG502S0PE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057546_1_3_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000123">
        <property type="entry name" value="Similar to protein tyrosine/serine phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF1">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="1">
        <location>
            <begin position="129"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="269" mass="29625" checksum="799A04D90257882B" modified="2014-05-14" version="1">MANLGPPFHPIAGIANFRDLGGHPLPIKSRPGYTIRSGLIFRSAEPSRLTEDGVSALQDLKISHVYDLRSRTEIERYATGTREWPGAQRVFTPVFLDEDYGPEAIALRFRNYTAEGSQGFVEAYRGIWETGTDSINTILSHLARPDPSPLLIHCTAGKDRTGVVCAFILSICGVDEGTIAHEYGLTEVGLGDFREELLAAVMKSPELRANPEGAQRLLGAKPENMLAALEALRKQHGSVEEYVVKNCGLTVEDLEQIRKNLIVPEESRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVI6</accession>
    <name>X0CVI6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Roadblock/LAMTOR2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01386</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GAMAD family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVI6"/>
    <dbReference type="eggNOG" id="ENOG502S7RW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113002_0_0_1"/>
    <dbReference type="OrthoDB" id="9985637at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="3">
        <location>
            <begin position="13"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK98485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="14735" checksum="8CEB64E47AE76C82" modified="2014-05-14" version="1">MAESSLTNGHDALEEKLGRLSKKPGVKASIVLDRTTGAILKTSGQIDALQTSKTRTTSTATSFSNEGPALEESETKGVEQFAAIVWNYVNSSGSLVQELDGEDELKLLRLRTRKQELVIVPDPKYLLVVVHDTPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVV7</accession>
    <name>X0CVV7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVV7"/>
    <dbReference type="HOGENOM" id="CLU_047998_0_0_1"/>
    <dbReference type="OrthoDB" id="5426775at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="287"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="350" mass="38445" checksum="C4FC617F52036F4D" modified="2014-05-14" version="1">MDGSLEPTPIQATPNNPRKRAARTSPSISPSDAQRLKKIRYEVDNQDINDPAMFQLAPIRSILPSAALLGYIKETQPRPSYLEQVDNWLEDTYPSDLRKTSSSDCFILDKDFEPILLERSHSAPAIMSGRKNLTGQAVTFELAFSPESSLKPSSPGFTSKEGGPSIDPTPTIYPTTTGTPNRSNGPLVESALYRDCNLALNNILLLDSRTELPPHISTLVESLKKGRSSPEPMPQDNDDLYDMEAGASEAKVEDFVRNNVIPLSSGIDKIKRSDRVFVGRAIIPITNPYARISVPVPDLLYGYRLSAFEQDQRMQIATCGNFAFANSEGLTFPFFAVEFKGDGPSSKGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWI3</accession>
    <name>X0CWI3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdopterin synthase catalytic subunit</fullName>
            <ecNumber evidence="4">2.8.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Common component for nitrate reductase and xanthine dehydrogenase protein H</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdenum cofactor synthesis protein 2 large subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdenum cofactor synthesis protein 2B</fullName>
            <shortName evidence="4">MOCS2B</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cnxH</name>
        <name evidence="5" type="ORF">FOQG_01405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + cyclic pyranopterin phosphate + H2O = molybdopterin + 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26333"/>
            <dbReference type="Rhea" id="RHEA-COMP:12202"/>
            <dbReference type="Rhea" id="RHEA-COMP:19907"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58698"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="ChEBI" id="CHEBI:232372"/>
            <dbReference type="EC" id="2.8.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MoaE family. MOCS2B subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.12" evidence="4"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWI3"/>
    <dbReference type="HOGENOM" id="CLU_089568_3_1_1"/>
    <dbReference type="OrthoDB" id="5531344at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990140">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030366">
        <property type="term" value="F:molybdopterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.40:FF:000003">
        <property type="entry name" value="Molybdopterin converting factor subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="entry name" value="Molybdopterin biosynthesis MoaE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03052">
        <property type="entry name" value="MOC2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028888">
        <property type="entry name" value="MOCS2B_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23404">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="Molybdopterin synthase subunit MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="116"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="139"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK98526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="164" mass="18393" checksum="B55AECE3906B74A8" modified="2014-05-14" version="1">MATQEKVQDLWELSEQDCYVALTHDHLNAQAIMDRVRSPSAGAIVLFAGTTRDNFAGKPVKELQYTAYHPRALKSMMAIAKDVRDKHGLRGVAMIHRLGPVPIAEESILIAVSSPHRQAAWRAGEEALEECKSKVEVWKREEFEGEEGIWRANRDGAIGQREES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWU4</accession>
    <name>X0CWU4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWU4"/>
    <dbReference type="HOGENOM" id="CLU_3279484_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="41" mass="4859" checksum="B7E26155034742F8" modified="2014-05-14" version="1">MERFQYSAAKPRLGGQRRLHALKRTKERGVKMKREETDPMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXI6</accession>
    <name>X0CXI6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alcohol acetyltransferase FCK4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXI6"/>
    <dbReference type="eggNOG" id="ENOG502RC91">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024469_0_2_1"/>
    <dbReference type="OrthoDB" id="2150604at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010828">
        <property type="entry name" value="Atf2/Sli1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07247">
        <property type="entry name" value="AATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="56602" checksum="CFB1923C12F41E71" modified="2014-05-14" version="1">MALREEPKVIRPMSNLELYHSALHTLRHSCGTAVVCRYSLPSHLIGGSFETIRNAFHRAMALIVVEHPMLQVGILNENSAVPSWIELENVDLGLHISWQEIKASDDYESSLKHEIRSQLDTWFTDVETKPGWRASILWPEGNIQSLDVIFCWNHTNFDGVGGKILHQTLLCNLNDSKTDHEPDLEGNVLHLRSTADRFPPPPEALIKIPISWGFALSTIWKELRPPILVSNDPTQANWAPIRQEPYQTEFRTFSIEDAMLKKVLSKCRAHSTTITGLLHALPLVSLALQLDEGKKHHKQEAKSMFAISALDTRRFIPTNSEAYPWHVPSTTMDNQMTLVSHMFGENLVAEIRSQAKGIPTQSHAMTQLENFVWAAAVQAREDIQNKLDKGMENDPSGLMNFVKDWRVQKKQQLKKPRVGAWGVSNLGTLDGAIEGSGWKIERAVFQLSCELTSPVFHISSISVKGKEMCVDVSWQQGIIDAEIGDTLASDMEAWIRFLGAGGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXM6</accession>
    <name>X0CXM6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_01823</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXM6"/>
    <dbReference type="eggNOG" id="ENOG502S9EF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053893_1_0_1"/>
    <dbReference type="OrthoDB" id="5425782at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007567">
        <property type="entry name" value="Mid2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04478">
        <property type="entry name" value="Mid2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938032" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Mid2" evidence="4">
        <location>
            <begin position="244"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK99240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="364" mass="37476" checksum="154BBB06E600ECA4" modified="2014-05-14" version="1">MYMTRLVKLLMVALAVVCVAQASWIDLNKIHLRERRLVRRASPSQSDDSQPSATAPDSKPSATQADPASDPAPTDAADPTSDDSAKTDAEATQATNEQTKPSATDAEPTNNDSAKTTAADPSPTNASPTSKPAEKSSAADSKPSETAAATQSEATDNAESSASATDAKTAAQSTTNSPAATSTSSNNQNSDDASSTASENNDEASSTAAEKNTRTTARPVTSTHVAVVTRTNSDGDLETMTTTSVSTSTPGLSDGGDDGSSSGMSAKTRNTVIGVVVGIGGAIVVGALGLVAWRIWGRKKHQEEADGLMDFNENNSRPSSNGPYHSVEKTEYGSVGSSGPQRSPFQSTLDTYHQPTPVNASSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ83</accession>
    <name>X0CZ83_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peroxisomal membrane protein 11C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ83"/>
    <dbReference type="eggNOG" id="ENOG502RACJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052213_0_0_1"/>
    <dbReference type="OrthoDB" id="10005898at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30906" checksum="A453736FF6311FE0" modified="2014-05-14" version="1">MISSPDCHKKPSILRNIQLGQFLSHLHRTIESREGRDVVLLFAGEAIRLVTFIMDLLASYLSRLQSQRLKGLSKSFFTISHINSMATSTTRVANCSRALCAMLDEWQIMNRLFGVLDMWKAARDLIKRVSAERSTGKPMKKLDIGIQTSQILCLTSFHVSEAIGFLSARGILKRSAKSEEKLTFLAIRSWAAFTMIEIGRLSLDWMNTMQDKEKLATKTWKAKWKSDMLQNLAWASVATHWSLRNGLIPEAFVSPLAVFATWSLVRDAWKNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D092</accession>
    <name>X0D092_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Solute carrier family 35 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_03543</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D092"/>
    <dbReference type="eggNOG" id="KOG2766">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039639_4_1_1"/>
    <dbReference type="OrthoDB" id="429955at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK96539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="408" mass="45049" checksum="61BBA63E0B8376C1" modified="2014-05-14" version="1">MSATQPIAVNTPENPSEGDSKGPTANATQAFIATNEDAAVSQGIHTLEVKSVHWYSYLTTVDFWIVLALGQVLALCITATNTFTSFLANAGTNIPAFQTVFNYILMFLIYTPIFLWKDGIKGWWRVGVKDGWKYLIMAFLDVEGNYFTVLAYRYTNVLSAQLINFWAIVCVVVISFFLLKVRYRIFQIIGIVVCCGGMGILIASDHISGTNGGSGLDMVKGDLFALLGATLYGTTNVFEEWLVSRAHLYHVLSFLGLFGMCINGVQAAIFDRDSFDNATWNGKVIGWIIGYTLCLNIFYILVPVMLRMGSAAFLNISLLTANFWGVIIGIRVFGYTIHFLYPIAFVLIIIGQLVYFVTGSMLSDSKKPWLGDNQEDGVLGFGTAKLKALNAARKAQMEAEAGQQDTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1D9</accession>
    <name>X0D1D9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar protein sorting-associated protein 55</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_02587</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OB-RGRP/VPS55 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1D9"/>
    <dbReference type="eggNOG" id="KOG2174">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134810_0_1_1"/>
    <dbReference type="OrthoDB" id="14246at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034424">
        <property type="term" value="C:Vps55/Vps68 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007262">
        <property type="entry name" value="Vps55/LEPROT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050">
        <property type="entry name" value="LEPTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050:SF0">
        <property type="entry name" value="RH04491P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04133">
        <property type="entry name" value="Vps55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK97368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="13903" checksum="E63D21F9F5D029A3" modified="2014-05-14" version="1">MPTAGLKTIIALSFVLAVGFLLVILSCALWKVYYPLLVVATYVIAPIPNWICGHCANPDDFVESSGAAVLDLGRFFTGFFVVMGIALPVVLAHSGLIEVQAMVMSIIGGLLIYGTIVSFGMFFHEEQDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1Q3</accession>
    <name>X0D1Q3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_08399</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1Q3"/>
    <dbReference type="eggNOG" id="KOG0281">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_103_4_1"/>
    <dbReference type="OrthoDB" id="19711at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="281"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="383"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="507"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="547"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="587"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="629"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK88612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="726" mass="81307" checksum="B7BC923B8F68F907" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D229</accession>
    <name>X0D229_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Origin recognition complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_02453</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the origin recognition complex (ORC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ORC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D229"/>
    <dbReference type="eggNOG" id="KOG2928">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018596_2_0_1"/>
    <dbReference type="OrthoDB" id="346673at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007220">
        <property type="entry name" value="ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056772">
        <property type="entry name" value="RecA-like_ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056773">
        <property type="entry name" value="WHD_ORC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04084">
        <property type="entry name" value="RecA-like_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24882">
        <property type="entry name" value="WHD_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 2 RecA-like" evidence="7">
        <location>
            <begin position="274"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 2 winged-helix" evidence="8">
        <location>
            <begin position="507"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="189"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK97159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="577" mass="63427" checksum="C90CD560CBE10377" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3H9</accession>
    <name>X0D3H9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L37ae</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_00881</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3H9"/>
    <dbReference type="eggNOG" id="KOG0402">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141199_1_0_1"/>
    <dbReference type="OrthoDB" id="10258345at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000002">
        <property type="entry name" value="60S ribosomal protein L37a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00327">
        <property type="entry name" value="Ribosomal_eL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050522">
        <property type="entry name" value="Ribosomal_protein_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00280">
        <property type="entry name" value="eL43_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003058">
        <property type="entry name" value="PRK03976.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXL00982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="92" mass="10147" checksum="517C5D9EB6B8656A" modified="2014-05-14" version="1">MTKRTKKVGVTGKYGTRYGASLRKQVKKMEVTQHAKYTCTFCGKVTVKRQATGIWDCKSCKRTVAGGAYTVATPAAAAMRSTLRRLREIAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4L5</accession>
    <name>X0D4L5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">FOQG_01399</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="19">Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4L5"/>
    <dbReference type="eggNOG" id="KOG4701">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007818_8_0_1"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02877">
        <property type="entry name" value="GH18_hevamine_XipI_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045321">
        <property type="entry name" value="Cts1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF47">
        <property type="entry name" value="ENDOCHITINASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="17 20" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="10 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="GH18" evidence="22">
        <location>
            <begin position="14"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="343"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="343"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="450"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00025727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EXK98518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="848" mass="88313" checksum="1A6B0EBB2981756F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6E7</accession>
    <name>X0D6E7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6E7"/>
    <dbReference type="eggNOG" id="ENOG502RYYT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004392_0_0_1"/>
    <dbReference type="OrthoDB" id="74412at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11282">
        <property type="entry name" value="ADF_coactosin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="751"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="823"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="838"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="870"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="933"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="993"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1048"/>
            <end position="1057"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1209" mass="131540" checksum="C8C81333FA728BCB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6I2</accession>
    <name>X0D6I2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07087</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6I2"/>
    <dbReference type="HOGENOM" id="CLU_2346741_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="97" mass="10975" checksum="DDDB9041C1A2AF0F" modified="2014-05-14" version="1">MQHFPVPACYSISHNAMASISAYQHTIPEVESERKNDHGDSYNNVNWTTATVRAVDWRYGAVSDTVSSLFQRRQIIAPTDLKNQRPEPLLAHPLKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D760</accession>
    <name>X0D760_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-dependent oxidoreductase-like enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D760"/>
    <dbReference type="eggNOG" id="ENOG502SZUB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="338"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="443"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="148"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="559" mass="62475" checksum="8E469803BDB53B38" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7G5</accession>
    <name>X0D7G5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sterigmatocystin biosynthesis monooxygenase stcW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_02029</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7G5"/>
    <dbReference type="HOGENOM" id="CLU_006937_6_2_1"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF11">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK99508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="63654" checksum="C5C4D805DED4887B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9Z1</accession>
    <name>X0D9Z1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9Z1"/>
    <dbReference type="eggNOG" id="KOG0806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_2_0_1"/>
    <dbReference type="OrthoDB" id="412018at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07197">
        <property type="entry name" value="nitrilase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050345">
        <property type="entry name" value="Aliph_Amidase/BUP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674:SF16">
        <property type="entry name" value="CARBON-NITROGEN FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G02350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674">
        <property type="entry name" value="NITRILASE C965.09-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="318" mass="35065" checksum="1714FF70902378D9" modified="2014-05-14" version="1">MAVTIPSSSFKVALVQMKPKPLDAEHNFAHAAEQIRIAADQGAALAVLPEYHLTGWVPEEPSFALSPEDAGKYRKKYQDLAVELHINICAGTFVSQAPKPDDQQNAGARPTLLNTSDFIDHNGNLLGTYTKTNLWIPERHTLTSFVDHARNISKDDYAAPNPHQVIDTPLGRVGILVCWDLAFPEAFRQLVLAGAKIIIIPSYWTALDMCKDGLAYNADCERMFIQSALVTRAFENTAAVIYCNAGGPAAEGFFGCSQVALPIVGTVPGSFTDGEEAMRILDVDMRTVDIAERNYQIRQDLAREDWHYGYLKNTVARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>X0DAH7</accession>
    <name>X0DAH7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DAH7"/>
    <dbReference type="HOGENOM" id="CLU_2015398_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="14134" checksum="308DF2F48B7D1BD6" modified="2014-05-14" version="1" fragment="single">MFNDLADDRAMVKPSPSSLTYLFRIITAIKHLRRFTDRHAFAPRSTPQLSNLGTQHFSALSWYQQQNTPSNTQDSLCFNRPRLVQLSEADEQHQQRRCTIQARLISPLLISGTALDFARPSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0DC54</accession>
    <name>X0DC54_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">endo-1,3(4)-beta-glucanase</fullName>
            <ecNumber evidence="3">3.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_00734</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;3)- or (1-&gt;4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3.</text>
            <dbReference type="EC" id="3.2.1.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.6" evidence="3"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DC54"/>
    <dbReference type="eggNOG" id="ENOG502RGZ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016972_4_2_1"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02181">
        <property type="entry name" value="GH16_fungal_Lam16A_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000114">
        <property type="entry name" value="Probable endo-1,3(4)-beta-glucanase NFIA_089530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005717921" description="endo-1,3(4)-beta-glucanase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="8">
        <location>
            <begin position="17"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="331"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="435"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="477"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXL00665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="509" mass="52761" checksum="F97D53963F39EFA0" modified="2014-05-14" version="1">MHSSILALGLTAFFNGAFAQNNSYSRYSLKTTYDSSNFFEAFEFFNEEDPTHGFVDYVDADAANSEGLAGYVDGAVYMGVDYQTKNPSNGRRSVRVTSHDAFTHGLFVADIAHMPGSIPGVWPAYWMFGPNWPTSGEIDILEGVNTQTENKISLHTGPGCSITNDGTTQGTTLESENCDSAGASAGCGQNTSDNQNYGDGFNDIGGGVYATEWTSDHIAVWFFHRGRIPQDIQSGNPTPSSWGPPAAKFNGGKGCNIDDHFKENNIVFDTTFCGDWAGSPDVWGKNPETSSLGDCKDYVANNPADFKNAYWLVNSIKVYVQGGSYGGGNGTTGGGNSGSGNSGSGNSGNGNSGNGNSGNGNSGNGNSGNGNSGNGNSGNGNSGNGNSGNGNSGNGNSGNGQSGNGDGQTNPPSSTQPGQGTQNGQQGQNGDGYSPDSQQGQDQGNGYTPEQQQGQGGGYSTGQSYDNGQYHGPGAYKTTKSQSSGTTSWDGNGWRVGSKRSVISKRYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0DEL4</accession>
    <name>X0DEL4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DEL4"/>
    <dbReference type="eggNOG" id="ENOG502SI47">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027146_1_0_1"/>
    <dbReference type="OrthoDB" id="4360026at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="501" mass="57725" checksum="2FC02A87AA7CF1CF" modified="2014-05-14" version="1">MLDRLELRTDQEKAIRGDGVPRLLEDRDSRAALIRGIRLHYHSAMSEPVRRLSSSMPQVARARNARRIMSNDIPERMTAEEQPYCIWHPDMATEDTYRSLASKFPGMRYQVGRACAAAGYHVLYQELDLLPEVSIAEEARESETDGGKLIYDEIMSFKSRYAIMDDCKRTIELMDYECPAYLNGNTEVRWRLAARQGITRWSNDDLLPCIEEDMHLGLEDQEVDQRHGTLTDDEAKLLYSPLPRDLPTVKKTLLTQMAAHDGNIERYAQLANSERTLTQLDQDCVIRGVLHHTMYARWWADQIKNDTIYARSAPYVWDIQRAIMARRIMLNDASVFEDGWPPGVPMPYIIWWPLQPQSDMLSLLAIKVPEMKRQCAAAAIVCDYENVYKNLDPEPSWHLWKVASEFAANPFYREDQEWRGRENDVDVKDDSFMESYYSELMQTRETTVLEEGGEKIPDSVEKHELLTNMYGSVEVLSASPVQLRIWEGTGTVSPISGRLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0DG56</accession>
    <name>X0DG56_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_04749</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DG56"/>
    <dbReference type="eggNOG" id="KOG2431">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003818_0_1_1"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000037">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF89">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="417"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="462"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="548"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="374"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK93462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="560" mass="63538" checksum="4F7F972F85A591CE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0DHH3</accession>
    <name>X0DHH3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VTC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DHH3"/>
    <dbReference type="eggNOG" id="ENOG502QPI4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015126_0_0_1"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345:SF1">
        <property type="entry name" value="VTC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="818" mass="92418" checksum="0C8F50E2127C9C21" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0DM41</accession>
    <name>X0DM41_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleoporin POM33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_04014</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PER33/POM33 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DM41"/>
    <dbReference type="HOGENOM" id="CLU_065417_2_0_1"/>
    <dbReference type="OrthoDB" id="5581259at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071786">
        <property type="term" value="P:endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051645">
        <property type="entry name" value="PER33/POM33_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005344">
        <property type="entry name" value="TMEM33/Pom33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03661">
        <property type="entry name" value="TMEM33_Pom33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="31435" checksum="7A6A1F3B430A4541" modified="2014-05-14" version="1">MAPPPNPNLPLQERLLALAKTLQFGWFVGHLTLILTTGRYFLSWIRMNYYTRMAQLSYRTAFIAAAVTYGIVVYKTMRARAKTGARAAPTPMALLADENIQYLAMALVWLFSPQYPLALIPYTIYSVFHVATYTRANLIPVVLAPKPAPEAADGASPSRQAVNSPLANQIGAFVKEYYDASMAIVSSLEIALWGRILLSAILFQRRSWILIVLYTAFLRARYSQSTHVQNSFTQLGARVDSLVSAQGTPPAARQVWQGVKEAGKQFHDATDVSKYISGPAKKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DR90</accession>
    <name>X0DR90_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DR90"/>
    <dbReference type="HOGENOM" id="CLU_141743_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="157" mass="17527" checksum="851984FA4B18B6CE" modified="2014-05-14" version="1">MVRNITRRRLRNNVQFWIGFTSNRPPGGHGTTIFHGSIAAELIRKHGGQRSKLQSAIWQTISHRISFADSLTPQSLGLWLLHIIDAQEGVLGKLRLGCSITSIPELNTPYQRRICVGWMNNLNGGFKKTDNTHCQCLTTNLNGQHNFAGLLPGSSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0DRK2</accession>
    <name>X0DRK2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_02306</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DRK2"/>
    <dbReference type="eggNOG" id="ENOG502S87A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090067_1_0_1"/>
    <dbReference type="OrthoDB" id="432881at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140575">
        <property type="term" value="F:transmembrane monodehydroascorbate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08761">
        <property type="entry name" value="Cyt_b561_CYB561D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045150">
        <property type="entry name" value="CYB561D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422:SF45">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="12">
        <location>
            <begin position="42"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK96907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="250" mass="26898" checksum="649752F06B9F8984" modified="2014-05-14" version="1">MASAAGVPERFPPIEDLSARETEPLLGRPGDAAQEDGVPLIKNLVLGTGIVAQLGVVLLTILIWASVLSKPLILFSAHPLLQSLAVLTLAQSVLSLQPTHTAEQKRVGQRVHASLNLVAFLILVAGVTIIEYNKIANNGPHFHSVHGYLGVITSIVLLLQYGVGFTMWATPALYGGVDNAKAVWKYHRWSGYIIFVLLLTTVVSAVETDYNHNVLKIKLWAVLLLAIVTLVGVVPRIQKQKLGFPGPGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0E0A0</accession>
    <name>X0E0A0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E0A0"/>
    <dbReference type="eggNOG" id="ENOG502S8V4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057546_2_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF10">
        <property type="entry name" value="PROTEIN PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="1">
        <location>
            <begin position="164"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="290" mass="32737" checksum="EAF494B2B5381958" modified="2014-05-14" version="1">MTSSVGLENVLNFRDVGKTVNDFLGTRRIREGLFYRSARPDNATLSDRQLIRDELGIKTVIDLRTKTEHLNQAQRRKEQSNIPALVKSNKALAGPLQISGLDYRQVKITGRPFELFLLSQLSWWDFFRVVFLFVCGYRTEAINILGQQVMIPRGLVGLGLDTIDQSTREIREALSLYANQAALPSIVHCTQGKDRTGLICALVLMILDVPVSAIEYDYALSDEALIPEREQRLVEIREIGLTDEWLHTADDMIVGVQKHLDDKYGGLNAYLDGIGFGADKRAKIRDLLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B165</accession>
    <name>X0B165_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979763">
        <property type="protein sequence ID" value="EXK75855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B165"/>
    <dbReference type="HOGENOM" id="CLU_2867745_0_0_1"/>
    <dbReference type="OrthoDB" id="4984334at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="64" mass="6655" checksum="F1A11D8A2DF82CD5" modified="2014-05-14" version="1">MPGNNSALLVREAAGFTNPLPEAILTGQENINTIQPAPVLFDRNAWLAQNTTPGAPTTVAGLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1E6</accession>
    <name>X0B1E6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980091">
        <property type="protein sequence ID" value="EXK75576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1E6"/>
    <dbReference type="HOGENOM" id="CLU_2694471_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="74" mass="8013" checksum="C03616319233A9EF" modified="2014-05-14" version="1" fragment="single">MSEHSSSSSQGNEKPLKHESDTEDSVKLSDVPTLPHDPETKPEIPAQLQKEPTPGNEGGKEREDSSQSQNSTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0B400</accession>
    <name>X0B400_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_18413</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979439">
        <property type="protein sequence ID" value="EXK76855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B400"/>
    <dbReference type="HOGENOM" id="CLU_000134_48_8_1"/>
    <dbReference type="OrthoDB" id="5428055at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="401"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="434"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK76855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="547" mass="60543" checksum="25848148E058D3AD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4B6</accession>
    <name>X0B4B6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658657">
        <property type="protein sequence ID" value="EXK76980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4B6"/>
    <dbReference type="HOGENOM" id="CLU_1896324_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="134" mass="14943" checksum="C0DCA68A14A915CC" modified="2014-05-14" version="1">MPDPWPSAVLNMVGQVSCMFSTTSPLNNERFKVMARAYTRRAMMTGSHASSRFVFPMSITSMHVSTGCSGPKNSWLECLTARKQFKVVRRIIPLMKSLLLTTLSSQRPTDVGARVLFFPGVIGVQHHDLHFDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5K1</accession>
    <name>X0B5K1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658649">
        <property type="protein sequence ID" value="EXK77041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5K1"/>
    <dbReference type="HOGENOM" id="CLU_1468221_0_0_1"/>
    <dbReference type="OrthoDB" id="4115389at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="3"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="184" mass="21563" checksum="71F90226345CC404" modified="2014-05-14" version="1">MKAKPWGEHKDIIVQLYCNERRTLKDVRSIMREHHSFDASARSYNNHFRKWKIRKYNCKKRNHKPRMSPTSKASVSGSRSPPNVPVKEEVSETLSFTTSRRQSSPYRLPLAEMGRTGYPDYKWPQWTRPDETMLDNLYTPTQIMLPPITAFRQENDSTTGARHLQSLSDIYFTQLCDLNGPCHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAK7</accession>
    <name>X0BAK7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dioxygenase swnH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_16213</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PhyH family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658479">
        <property type="protein sequence ID" value="EXK79165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAK7"/>
    <dbReference type="eggNOG" id="ENOG502RUKM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047725_0_1_1"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF45">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="33411" checksum="A20603F8B68F4D9E" modified="2014-05-14" version="1">MPNPAHQRNNPEITALPATAPIEEIVSAIRRDGGIIIKGFITPDEADRIQAEADPHYQKVGKYEGTLFPPTDPPLSGFAGKSPTFAHKAINHPVYREASKLLLKEESYPFRDGKRYKCVSNPVLAVSEAFSRGRSKAQPLHRDDMAQHFDHVEGSGESSLLGLLVAGTKCTFENGATQVIVGSHLWPEAAISGPADRSMCSTAEMEKGDAVMIIGSVWHGAGANITDERRNIFSCHMVRGSYRADENQYLAIPLEVIKDYDPEVQSLLGYSVSHPNCGHVNMKDPIVMLGSNEDPFGYGSIEGQVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBF7</accession>
    <name>X0BBF7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979351">
        <property type="protein sequence ID" value="EXK79111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBF7"/>
    <dbReference type="eggNOG" id="ENOG502QU9T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029940_1_0_1"/>
    <dbReference type="OrthoDB" id="3162524at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="29"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="313" mass="36158" checksum="A7D4BDFE6ACFDBE1" modified="2014-05-14" version="1">MGKKKVLVCYGVDIDAVAGWLGSYGGEDSTSDISRGLWAGTIGTRRLLKLFEKYNIKASWFIPGHSLETFPEECAMVRDAGHEIGLHGYSHENPVDMTFEQQKDVLHKTWKLLTDFCGKPPKGSVAPWWETSEEGTELMLSYGIEYDHSMSHHDCQAYWLRTGDSWTKIDYTKKAEEWMKPLQKGKETGMVEIPGSWYIDDLPPMMFIKNSPNSHGWVNPRDVEDIWKDHFDYFYREYDEFIFPMTIHPDVSGRPHVLLMHERIIEHINKHEGVEWVTMAEMSDYFKSKNPAPEGALMPASHEEVMKKFQESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDT9</accession>
    <name>X0BDT9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_18287</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979427">
        <property type="protein sequence ID" value="EXK76988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDT9"/>
    <dbReference type="HOGENOM" id="CLU_044876_3_2_1"/>
    <dbReference type="OrthoDB" id="5090267at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF1">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="15"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK76988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="318" mass="34589" checksum="DA4757EC0E0E02ED" modified="2014-05-14" version="1">MKDLRSRVKNVALAGATGMLGSHILAAFSQNKRYNLTLLVRNNSSIGSFPLHITVIEVDYDSHESLVSALRGQDVLVSALGKAALHCQGRLVEAAVAANVRRIIPSEFGANLRNPKTREFPTYALKIALEDQLARSCRLSNSSYTLIYTNCLLDWAIATHGALLVDPSKRIVKLYDGGNNKFSTTSLATVGRTVVAVVDHFEETANRVICVQDAAISQVELLELVKEVTADDGGKEWGVLHIDTGDAEAQALAVQKQGALTSEVFYGFAVRAAFAPGYGGHFAHCDNELLGIKGMGRDEIKRLIQHVFSEEDQQDLCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDW8</accession>
    <name>X0BDW8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979342">
        <property type="protein sequence ID" value="EXK80016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDW8"/>
    <dbReference type="HOGENOM" id="CLU_140471_0_0_1"/>
    <dbReference type="OrthoDB" id="3521820at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936867" evidence="2">
        <location>
            <begin position="20"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="159" mass="16166" checksum="A02C13FA73EB7312" modified="2014-05-14" version="1">MTQLTKLLIILAAATATLGAPTMKPRQLAGEGSFFDSVFTGTDNGVGYGVENAEDNAATLLGGKATSGGGGSTSNPPPPQPKVKRQADKIANGAATDLHAVGQDKAADLVQTDGDNIDGQLTQDAATLGAQVGGDEEDVLERTGDMVPSKTPTRRARGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF66</accession>
    <name>X0BF66_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14716</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658436">
        <property type="protein sequence ID" value="EXK80770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF66"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="13"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK80770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="497" mass="54327" checksum="AAAA3F707E3BB7D0" modified="2014-05-14" version="1">MKSDAWLSKPFLTSIFLGIGGFLYGFDSGIITPSLALSSFLTYFGKPDPPLRGAIVSMYQAGAWLGSASVGITSDKLGRRKAIAFGCIWGVIGGAIMAGAAHVAMLIIGRLLVGFAVGTITGVSPVFGAEIAKTHERAKVTAVNQMMTAWGFFVALWIGVAEGKWHNANQWRLGFAIQSIPALILGVGVLFLSESPRWLCLKGRHDEAEKAFRAYHYDGTNDDWCRTEFTVIQVNISEELQAQGRLSWADLVKTPAFRKRLFVGSFVWAAAMLSGISFVQYYQTAIYATLQFSEDRQLLVSGLYGSVAPVACLISLFFVDKIGRKKILVISSSLLSLCYLIITILAARFPAVPGMPTNAAAQRGLIACIFAVSANYSALLGPMTWIIPPEVFTTELRAKANAIVQVVHYSISLIITQCSPIALAAVGWKYYILFVLTNAMCALIFFFVYPETRGKSLEEIDEIFGDVKIVHEEDVRFSEKTGVEAIETRDQRIMQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF80</accession>
    <name>X0BF80_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658443">
        <property type="protein sequence ID" value="EXK80471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF80"/>
    <dbReference type="HOGENOM" id="CLU_2622145_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="78" mass="8906" checksum="98583420B8AFD392" modified="2014-05-14" version="1">MSITNARLEQIRNFETKISSELDWIRREKERLQEILSIVEGIPSSVRNQMSGSASSSSKKKAEVKLLVLMKRSLDTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFN3</accession>
    <name>X0BFN3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658432">
        <property type="protein sequence ID" value="EXK80965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFN3"/>
    <dbReference type="HOGENOM" id="CLU_059039_1_0_1"/>
    <dbReference type="OrthoDB" id="5429716at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="311" mass="32795" checksum="B29674205851A2ED" modified="2014-05-14" version="1">MPTATEYFGIGLTNNGPLTTTYTPPASCTTVTTNQIFFANPDSISEGYGAPTCETASMGKCLPSGSNYDKQVAYLNEYGGQGAIDYYSPGIACPKGWTTAGTLAHGNETGSVEKSGVFTQTRSTLPGVSVTDPNMPLEQIWLNALGPSETLAYCCPSGWVAAKGGGCFSSIEPLKSATYTEVCIKYLPQSAMRSVYTVEGSKVSHYLYSAATVGPTSVIWPMSAVQTESRFEYDELAVVRRFPAVKLVYKESDLKSTGGGDESNDGKSGDDDDDKKEDDDNGASGLLSSGGLISMIAVLFSMLFGAGLVMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI03</accession>
    <name>X0BI03_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="9">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_17215</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="KI979367">
        <property type="protein sequence ID" value="EXK78104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI03"/>
    <dbReference type="eggNOG" id="ENOG502QTDU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027551_1_1_1"/>
    <dbReference type="OrthoDB" id="2425929at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF3">
        <property type="entry name" value="FERULOYL ESTERASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 9" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5029032792" description="Carboxylic ester hydrolase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK78104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="297" mass="31951" checksum="F55239436E5DFAAB" modified="2014-05-14" version="1">MLGLPSPRKLLTQLSLGASLVAAQLQTITNFGNTYGTQLTMQAYIPGNLPASPAVMLALHACGGNGPGYFQQTKYKSLADSRGVILIFPSSQKDFNCWDVASTKTLKHDGQGDSQVLVSMVDYVIKTYKADPKKVYVTGTSSGCMMTNVLAATYPDRFAAATCYSGVAAGCMAGSPGSSPISSDRVCSDGKIIKTGQQWADQVKSMYPGYSGSYPRFKTWHGTADNLVFYRNLLEQIKEWSTIQGVSFTRNETSTPQSGYTTMIYGDGTKFVAVSAAGVGHVVPTHEDLDFKWFGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI25</accession>
    <name>X0BI25_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_17189</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658544">
        <property type="protein sequence ID" value="EXK78124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI25"/>
    <dbReference type="eggNOG" id="ENOG502SHUR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019101_0_2_1"/>
    <dbReference type="OrthoDB" id="5035861at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF2">
        <property type="entry name" value="SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="19"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK78124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="360" mass="40068" checksum="A98EE9513691B3E5" modified="2014-05-14" version="1">MADPEAWTLLALGLWFIGMRMWVRWTQVGFSGWQLDDYLMPVTGVVFTLETAAAYLVGARFGGLTNSYMTDEQRAALSPDSKEYSDRVWGSKIQVIGWSFYVFILWSLKVCLAVFYSRLTSGLAHLTMRVRIAYVLLGVTYVAVALSILLGCQPMERYWQIYPDPGNLCQPTISRLYVLVVVIPNVITDLYLLSIPLPLLWTVNISLYRKLTLMVLFSGAIFVIMAAIIRAVVILSAGPEGAISGSQWACRETFVSVIVTNLPVVQPLVRKCADRVGLSALFSRSTRAAHSYSLRSREVRGDCELRRKTHTNLHSVPQGAAWDSDEHILGMMDQVAQELSTQTDVVAQREPGASGEESSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIV8</accession>
    <name>X0BIV8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658523">
        <property type="protein sequence ID" value="EXK78399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIV8"/>
    <dbReference type="HOGENOM" id="CLU_1294454_0_0_1"/>
    <dbReference type="OrthoDB" id="6846267at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="21787" checksum="8A603C8FA79FA9C0" modified="2014-05-14" version="1">MKQLSTACVNPAFDYDSLVVQLSNYYPEKVTKALLQYYTLPTTVADKDEWADIGSIIIGDCQVHATIRGFTASLLKTMPEERVLRYRISWRAKALDNWLQPSIGMCHASDIPIWWACGRRAGYEQADLDLVSEWLNTFYQYLCGDKPAWGATGLNMIKELKAEGKVEDMEDANLDKGLEVWNVMIKAQLDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKH0</accession>
    <name>X0BKH0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_13073</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKH0"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_2_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF305">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="262"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="456" mass="47591" checksum="DF01AE4124BBA2FE" modified="2014-05-14" version="1">MATNTVAESITTSSMDPSCQGDAIEMSSSSQSPLNTTEDIVRNEEEPPEHATSAIPDGGYGWTIVASCFTLIFWINGYTTAWGVLQAAIVQSPRLHTNIRTITFVGSLYMACMVAFGLISVRLSREYGIRITSLVATIFFGSGLIITSFTLEHLAGLFCIAGLLVGLSTSLLFTATNTMPTQWFSRKLGTANGIVKAGGGVGATVLPLATQAMIDKVGLQWTFRILGASILVTGIPCAFLLTELTRGATTSRFDWSQLKSMPFLTLTMSGAVGVFALFVPPFFLPVFARSIGLSASTGAGLVAGFGASTAVGRLFGGWICDRIGAFNSLALAALINSVSMLAIWPVSSSLPPLFAFAIINGCANGSFFVALPTAVAALAPGSAAASISLMTSFWTPGYLMGAPLAGILIDAAGASEASSIEPYRAAIFYAAGVGSAATFLIVVSRLMLSKKLIKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMQ3</accession>
    <name>X0BMQ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5071 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658462">
        <property type="protein sequence ID" value="EXK79734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMQ3"/>
    <dbReference type="eggNOG" id="ENOG502SMVK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083671_0_0_1"/>
    <dbReference type="OrthoDB" id="2969215at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11743">
        <property type="entry name" value="Cthe_2751_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.750">
        <property type="entry name" value="Domain of unknown function DUF5071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038692">
        <property type="entry name" value="Cthe_2751_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031837">
        <property type="entry name" value="DUF5071"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16804">
        <property type="entry name" value="DUF5071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5071" evidence="1">
        <location>
            <begin position="137"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="278" mass="31776" checksum="FBA93018EC9627E5" modified="2014-05-14" version="1">MNREQLSTLDERAFAEKLPTMLWSDRETLFEDGSEDIDIIRSRAAEPATVEAISSVLTSPIKDEDYDTLRVHQKALYSVLLKLPFEKLQPYRPALAALAAFDISGFAHHSSHYAQTFHVIRNAGHLERFAADAKAVWVTKDKFDMVSDRTLTERVHTAEEMRPYMPELFGWLVDANNPPFMPCRNQLARFPETAAIVAAEVLAKANKEKDGEYQHFLIDFVSDCVPVGEAWKPMREHVQALVKDLKGSKSEDDEELVDEANEWLTKLEQWEALKKEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP14</accession>
    <name>X0BP14_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tc toxin complex TcA C-terminal TcB-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP14"/>
    <dbReference type="HOGENOM" id="CLU_060778_0_0_1"/>
    <dbReference type="OrthoDB" id="4940706at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040840">
        <property type="entry name" value="TcA_TcB_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18276">
        <property type="entry name" value="TcA_TcB_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tc toxin complex TcA C-terminal TcB-binding" evidence="1">
        <location>
            <begin position="16"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="270" mass="29703" checksum="8037920F2B81B503" modified="2014-05-14" version="1">MSEDSSQHSSCKLTYDNISFRQLNPEALLNLRANGTVTFEIPEVLYDFDFPGRYMRRIKSVSLSVPCVVGPYTGLNATLRLLQHRYRVSSVAASGEDYAGDGMASGHFRTDIAPITSVAISFGIQDSGVFELNFKDDHFQPFEGAGAIGSWSLELPTVVRSFDYSAISDVILHVRYTAVDGGPLLRNAANQAVKTFRSRVEGLSSEGPGLFAMFDLKNDFSNAWYAFRSGLASKTIEEFDLSGIKDRFPYWALGKTIIIAGLSLVVSVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQY9</accession>
    <name>X0BQY9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQY9"/>
    <dbReference type="HOGENOM" id="CLU_057885_0_0_1"/>
    <dbReference type="OrthoDB" id="5100136at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935910" evidence="2">
        <location>
            <begin position="22"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="347" mass="36354" checksum="209A6A4977E0A25B" modified="2014-05-14" version="1">MIAPNRLVAASLMLVFGQTNAGPCRPSSNSIVLSSNVGIHESSTLTKAQSATSGASLSDASTISHIYTGTTSDATAMSLSTSITISLESTTTTFSTATESQDTIVDTTSGATKETQSTSEAPSTEAATPKTEQTTTTVLGSTTETTTEAATTLAQEITTTTAESTTEPLASSIETTTITTAALAAPTFNLIAQGGLSDGVVLHSSGQYFQIRTSQYTTPYPATFPEAALSYDQETQHLVIKGVPLCVYYDTQGIIGGLYACQGVPTGQYGYLTCDPPSNGGLACNVPGLQYDQPSSSLIDLGQTWSQFYYLEQMTGLGTLLIGRAGLTKNEIKYNRFDPINILVREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR45</accession>
    <name>X0BR45_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14559</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658432">
        <property type="protein sequence ID" value="EXK80949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR45"/>
    <dbReference type="eggNOG" id="ENOG502SNQ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021599_2_2_1"/>
    <dbReference type="OrthoDB" id="3525185at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF11">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK80949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="532" mass="59149" checksum="DA943A590DC9E928" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR47</accession>
    <name>X0BR47_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658432">
        <property type="protein sequence ID" value="EXK80954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR47"/>
    <dbReference type="HOGENOM" id="CLU_125065_0_0_1"/>
    <dbReference type="OrthoDB" id="2520703at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="186" mass="21422" checksum="E94B0C1D3EA8101D" modified="2014-05-14" version="1">MRFSEFSMPRFSADVIEKIRDYRHSLETLHLDLRDVIESSPSYRPDCTFHDFEKLEHVFLNTRLVFHTLRDLEGIDGPTVEDRHAITRLLPPSIVSLHLVWDGLEIDRLEQGLMGLVGATTDRFQHLKLVGLDYAERLDETVHHAMLELVLSSHTSVGQSLLRVSQVRKNLMMNGWVMGSNEAVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRG5</accession>
    <name>X0BRG5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658430">
        <property type="protein sequence ID" value="EXK81079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRG5"/>
    <dbReference type="eggNOG" id="ENOG502TIEG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128312_0_0_1"/>
    <dbReference type="OrthoDB" id="5018207at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="13852" checksum="BA11901D95EAFCA7" modified="2014-05-14" version="1">MYLRCVTATESYFYQAQQHVYSVRLMQNDLRNTLASITDADIKFGQEMRSSYAQFLSHISCYAGDDTQALASLSTITGTFDEFNLQQHQRLTTMRDQLDSYTLVLRKIAALKHGLEEQGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS20</accession>
    <name>X0BS20_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979335">
        <property type="protein sequence ID" value="EXK81274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS20"/>
    <dbReference type="HOGENOM" id="CLU_061751_1_1_1"/>
    <dbReference type="OrthoDB" id="191037at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="221"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="305" mass="34473" checksum="17522FAF2F237F65" modified="2014-05-14" version="1">MSQIGALRKDIVEHVRRSCKEEELNPPVPREYGDIPVSYEAITKEWLTATLARDVFRSTIKSFSLGPKDDGSANRRRIEIEWEGFGAHKLPTSVFCKAAHSAENRIVLAAGGTYSEVCFYTHIRPQLNIEAPWAYFAGYDPKSWAAIVILKDMGQETTFCNYKTGLTKAQFAEQVQMLAKLHSQYYQSQHPDFERLLIYKDRISNLIEVGLETMCVNGFRAAKSVIPPQLFARQNEIWPCTLKSVERNAALPATVVHGDVHLGNWYITPGGHMGLTDWQTVARGHWSRDLAYVLGTAVSAEKRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSP6</accession>
    <name>X0BSP6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_13608</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK81958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSP6"/>
    <dbReference type="eggNOG" id="ENOG502RKVX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040729_9_3_1"/>
    <dbReference type="OrthoDB" id="442317at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00878">
        <property type="entry name" value="Arf_Arl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003500">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 13 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 13 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="20"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00070396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK81958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="187" mass="20884" checksum="2D589A9F747460E3" modified="2014-05-14" version="1">MGATVSQLWAPEPIAIGFIGLRSAGKTTIVHKLSGNQEPAMPSVESESPFPTTVEITPVFQGNQQFKLFDYAGNPHWRPCWRSFMSRLRGVVFVIDSTDREALQEAKAELVGLLKEEMLEQQPFLVLANKQDDPKAMSVAELTEYLDIQHYLDKSSKCRVQPTSALTGEGLAAGLDWVRNALREHRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSX5</accession>
    <name>X0BSX5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ANX-14 annexin XIV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_14008</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the annexin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658425">
        <property type="protein sequence ID" value="EXK81594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSX5"/>
    <dbReference type="OrthoDB" id="37886at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0041">Annexin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="61"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK81594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="54302" checksum="25E9CB12B7946559" modified="2014-05-14" version="1">MSQQPPYWQGSQGGAPPQPGYPGQQQPGQGYYQPPPGQQPPYGYQQQGPPGGQPNQPYPPAGQQYPPSGQQGQYQQHSQGYPQQPPYGQQAPGHQAPYGQQPPPAPYGQGQYPPQQYGGPQQGQPPYPGQQQQQPPYPGQQWHQQPGQQQYGGPPVNVPPTPASPGYDPAQKAWVKPVDTAADVEALRKAMKGMGCDEKALIRVLVSPKYADPWTMAQLVRDYNSRFMRDLAKDIESETRGDFETCLLALIRGPLENDVQNLSKALNRAGTDEDALNDVLLCRSNADIRAITAEYKRFRGKELLVDIKEDVDDTLYRLYSMVLAARRAEDNAPVIPHEIDQKITELQRATEGTIGANAVSVAQIFTSSNDAQVRAMNDAYQHKYHRSLESVIEKEFRGDMEDVLLRILYHAQDRARSDAGRLSMPLNKSMRKDRLFINRLVSLYWDQGRLYQTKQAYKPVTGATLSGNIKSVLSGDYKDFALALIGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTC5</accession>
    <name>X0BTC5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_13893</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658423">
        <property type="protein sequence ID" value="EXK81724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTC5"/>
    <dbReference type="eggNOG" id="ENOG502SJ6K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019101_2_1_1"/>
    <dbReference type="OrthoDB" id="3903189at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF110">
        <property type="entry name" value="UBID FAMILY DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="25"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="276"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK81724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="386" mass="43468" checksum="B39457F7F5E42B56" modified="2014-05-14" version="1">MDFLHKLLVESWVLWVLGLFVVVCRLISRRMKLRKWSRLAIEDYLMVFALVNFTGVVVSINEVAEKGSNYMPADVAAKLTPDGRQQAIIGSKMTFVLEIFALTCTWTIKACLLFLYARLTQGTSIRQKWAVRFVSAFCAVTYIVVTFMFVFFWCSPTPEYWSVPVNPKKMQCATYYNHMIFATACNIASDIMLILLPIPIVVNISLPKKRKIGLCCVFGLGLFNILAAVLNRYYNFSNPNSYVFLYWYVAEGGVALWVGNLPLCWPVLRLAIGSKGDSTDPSSYPNTPYRNGSYPEGSARRRTQGLHPLSSKPSIWAKLEDEDGVRTDVSPEQGSQIELVDQHGPDLLQRPYRAEAKISSGTQQHERARSGQITVVTSVEVSTKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTI7</accession>
    <name>X0BTI7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secondary metabolism regulator LAE1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTI7"/>
    <dbReference type="eggNOG" id="ENOG502QSKG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_1_2_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF31">
        <property type="entry name" value="LAEA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37959" checksum="3B227C5A332150CB" modified="2014-05-14" version="1">MASPAAQPTAERAESPPDVPGVLEAEDYGGDTDSTLDLGEGSSSYMTSLKSSIFSYRYEHGRRYHAFHEGAYLVPNDDEEQNRMDLVHHIYSLLLAGKLHTAPIDNPQRVLDLGTGTGIWAIDFADEHPSAEVVGTDLSPIQPDWVPANCVFEVDDFEDPWVYKKPFDYIHARELEGCIGNEQQFFDRAFENLNSGGYLELQAQRGFFMSDDDSIKKAVNAEVWAEAVRDSSNKFGKPIDCAMNWKEKVIKAGFVDVHEEVRKIPIGAWPKDPVLKEVGKCQVVQSCAAIDSYTPMLLEKVLGWGKEETQVLMAKAKGELRNPSIHLYLPVYFIWGKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTW0</accession>
    <name>X0BTW0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13693</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658419">
        <property type="protein sequence ID" value="EXK81934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTW0"/>
    <dbReference type="HOGENOM" id="CLU_009834_3_0_1"/>
    <dbReference type="OrthoDB" id="1696280at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF75">
        <property type="entry name" value="ENOYL-COA HYDRATASE_ISOMERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="25050" checksum="A8B35E164DABA04A" modified="2014-05-14" version="1">MHQNLGLERRGDVFILTLQKPPENRLTSQFCQEIIRALNDVRRTLGPDAPGAVIIRGNDAKFFCRASSEGSYPLVATLLHFPFPTICLITGHTFGGASVMTLAHDYRIMNDTLGYWCTPVAELGLHFDGMGALLRAKLPQKIARKVILQGHKFTSSEALADGIVDEIASPEEMLNCALQLANRAKSKAKIGVYGLLKGELYGEALRAFQQISYVHSRLNSRQAKVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW29</accession>
    <name>X0BW29_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Unsaturated rhamnogalacturonyl hydrolase YteR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12963</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW29"/>
    <dbReference type="eggNOG" id="ENOG502QV67">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038720_1_0_1"/>
    <dbReference type="OrthoDB" id="540611at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052043">
        <property type="entry name" value="PolySaccharide_Degr_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886:SF9">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936025" description="Unsaturated rhamnogalacturonyl hydrolase YteR" evidence="2">
        <location>
            <begin position="25"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="43944" checksum="79D5D5222D6FE667" modified="2014-05-14" version="1">MDNMLRPLMRSLVTMLIGAECGLAYLTEMADTMIAKGVKPDLGYQDAVLYLGFEKAYELSGDQKYLDWYIGQIDGPVVQEDGSIKGLNTSRYILDEYRMGHNYLYLYNQTGEPKYETAANTVRRMLDSYPRTPSGGFWHQQFFRDQMWLDGIYMADSFYARWTHLYDSDNDTAWDDILLQYELIHENTINETTGLHVHGWVEGKASWADPKTGRAPNVWGRALGWYFMALVEVLQYFPTSHSGYDQLLGYLESVAKGLKASRDPDLGSWWQVMNEPYPKREGNFIESSGSSMFTWGLLKAVDLGYLDSDEYLETAKDAFTSLIDNFVTEGEDGSLILNSTVAECGLTSSNVTFKYYVSRPKLENGQNGVGPFMLASYEWESWAKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW65</accession>
    <name>X0BW65_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW65"/>
    <dbReference type="HOGENOM" id="CLU_220657_0_0_1"/>
    <dbReference type="OrthoDB" id="4964795at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="35" mass="3578" checksum="A6CC6AC4A092FD4D" modified="2014-05-14" version="1">MQPLVDYHDNTCPKCNAAIEGGGKTCGSCGAHCPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWI6</accession>
    <name>X0BWI6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="12">3.2.1.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Galacturan 1,4-alpha-galacturonidase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Poly(1,4-alpha-D-galacturonide)galacturonohydrolase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_09819</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="12"/>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWI6"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047911">
        <property type="term" value="F:galacturan 1,4-alpha-galacturonidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF6">
        <property type="entry name" value="EXOPOLYGALACTURONASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938924" description="galacturonan 1,4-alpha-galacturonidase" evidence="17">
        <location>
            <begin position="21"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00041473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK86550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="477" mass="53150" checksum="1104F42C9809B315" modified="2014-05-14" version="1">MRSLQIISVLGALFLTTVQAVTLPAGVPRDISEFRDKHPYAPPKHEHRRIVRIRASRNNADDVSDEFRRGVRKANGGGTLHLAKGKTYVIGKALDLTGLEDIHIHLEGEIRFTNDVEYWQENAWYHPFQKSIMFWKWGGKDIKIYGNGVIEGQGQRWWNEFESGTGSILNPDNKYYRPILFYAENTTNLDVSGIHLKDSPCWNNFIVSSKNVKYTDVVATALSNNGSIIPKNTDFMNTMNTSAVRIERTWVNIDDDCFSPKPNSSDLYVNTMYCNGTHGQSMGSLGQYKGEVSNVYDVHIENVWMMNGDYSAARIKVWAGEETGTGFVNNVTFKNFWVARMDYGIFLDSCYFNISAEECNAHPSGMQITNIHFENFTGYTSGVYGNAVARLSCSAAEDAICANITVKDFNVKTPCGGDPVIICDGMHGDIGVDCVPYDSDKAKAALNAKCKTPMAAIDTDPWGSGLIEKMKGAFHPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZP7</accession>
    <name>X0BZP7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11723</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK83994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZP7"/>
    <dbReference type="eggNOG" id="ENOG502SN08">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020821_1_0_1"/>
    <dbReference type="OrthoDB" id="5357734at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37576">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37576:SF2">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="588" mass="65296" checksum="3D627298433296F8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0P3</accession>
    <name>X0C0P3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979524">
        <property type="protein sequence ID" value="EXK76377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0P3"/>
    <dbReference type="HOGENOM" id="CLU_1489089_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="181" mass="19950" checksum="D13E0328DF3C9F42" modified="2014-05-14" version="1">MKPMNMAHRTAAAAPTLRWTSRLAALLSLSRPPSPGSLMCVTTSLITLKTRDFTSSSFPAIKVSVPSKAVPMVDALSLTSVSPRSRRLLPFSFTLSAISAMEERKLSRSRSKRTLGGAVSLGLVESRVRGGLSNDPWLLLRLIRTRQSGYERQTLTSDEGPRRPWQCSSKRVRAFLGSAYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2D2</accession>
    <name>X0C2D2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GTP-binding protein RHO3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_10678</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2D2"/>
    <dbReference type="eggNOG" id="KOG0393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_21_2_1"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017157">
        <property type="term" value="P:regulation of exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000780">
        <property type="entry name" value="Rho GTPase Rho3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK85318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="203" mass="22801" checksum="E121B2CA5177E7BD" modified="2014-05-14" version="1">MPALCGGSKTVQRKLVLLGDGACGKTSLLNVFTRGYFPTVYEPTVFENYVHDIFVDNVHIELSLWDTAGQEEFDRLRSLSYDDTDLIMLCYSVDSKDSLENVESKWVGEIADNCPGTKLVLVALKCDLREQGEEEENESGEPREKRPMINYDQGLEVARRINALRYLECSAMKNRGVNEAFTEAARVALSVKKDREEGGCTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2N7</accession>
    <name>X0C2N7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2N7"/>
    <dbReference type="eggNOG" id="ENOG502S495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015886_0_0_1"/>
    <dbReference type="OrthoDB" id="5206661at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="595"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="672" mass="74879" checksum="53284C3C444C8EC8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3C1</accession>
    <name>X0C3C1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Azaphilone pigments biosynthesis cluster protein L N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_18025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658626">
        <property type="protein sequence ID" value="EXK77262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3C1"/>
    <dbReference type="HOGENOM" id="CLU_010556_0_0_1"/>
    <dbReference type="OrthoDB" id="195446at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF48">
        <property type="entry name" value="PROTEIN VAPYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="351"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="458"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="527"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="594"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="37"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK77262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="733" mass="82505" checksum="BBABF0788BC86458" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-01-24" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3Z8</accession>
    <name>X0C3Z8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3Z8"/>
    <dbReference type="HOGENOM" id="CLU_648970_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="423" mass="48473" checksum="54D3689B24D4C571" modified="2014-05-14" version="1">MALNRVAPEILLEIFNHVDHEDLRKLCAVSHRLMSAFEHQTYSIIELNETSQSGSALLALASGPRRDIVREIRYNPHHPWPARDRRHKPEIKLSDETRTALQSLTFFPSLEKFKFDLSHWELSEWALSPQCLNRWEFHLWHGKHDTEPWRVLIEGSLLALSKSARSFSRLEIDSLPPTGREAYRACESETWKDLLKHLASFEMTLAGVGYMGHGGSYMYGKMTSAHQAFITLFPEMFLENLHNVQVLRLTGKMNAVMGNEQLVEPINWASPSINLPCLTTLELDYSQISSQLFAFLSKHAGTLEKISLRNCIAPAKQIWTNIINLFLDRQPKQLLEFTTTARPVHKRIGDPFADASDGLDVKMRRFVVGLANHDIVPVEEWAAVSDDDPELDESDVCKLWDQLEEMLERNRCHARGLLQEASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4M7</accession>
    <name>X0C4M7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Replication factor C subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_07981</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4M7"/>
    <dbReference type="eggNOG" id="KOG0989">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042324_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000011">
        <property type="entry name" value="Replication factor C subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000237">
        <property type="entry name" value="replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF20">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="65"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK89360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="382" mass="42288" checksum="50856106382B4789" modified="2014-05-14" version="1">MASFFDLKARKAAAAANGNADQKQDKPSNARTQPWVEKYRPKTLSDVTAQDHTVDVLQRTLQSSNLPHMLFYGPPGTGKTSTVLALAKELYGPDMIKSRVLELNASDERGISIVREKVKNFARMQLTNPAPGYKDKYPCPPFKIIILDEADSMTQDAQSALRRTMETYSKITRFCLICNYVTRIIDPLASRCSKFRFKSLDQSNAKRRLEEIAEKEGVALEDGAVDALIKCSEGDLRKAITFLQSAARLVSANAPDKEAEGDEVMDVDKKAATVQIVEDIAGVIPDTTIDDLVKAIRPKRSGSSYQIISDVVEKLVADGWSAGQVVNQLYQALTYDETIPDAQKNKIVLVFSEVDKRLVDGADEHLSILDLSVRISNIMSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4V2</accession>
    <name>X0C4V2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isomerase YraM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07546</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpF family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4V2"/>
    <dbReference type="eggNOG" id="ENOG502SHIK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026443_0_1_1"/>
    <dbReference type="OrthoDB" id="10267539at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007400">
        <property type="entry name" value="PrpF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43709">
        <property type="entry name" value="ACONITATE ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43709:SF2">
        <property type="entry name" value="DUF453 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G00360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04303">
        <property type="entry name" value="PrpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK89445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="43900" checksum="572E9DD94CD60525" modified="2014-05-14" version="1">MAIEIGTPQEHYPTRHALSCVLMRAGTSKGLFIHRKDLPEKESEWGPHLISALGSRNNDAKQVDGVGGGSSTTSKVAVVSLSNREDADVDFTFVQVAVGKESVDFSGNCGNMSSGVGPFAVQERLVTPKPGQTEIDVRIFNTNTSRIIVETVELDRNGDFKEDGDFIIPGVKSPGSEVKCSFVDPAGSMAGSLFPSGQKQQWLHVDPSSLLPEMAPFQIRATLIDAANPFVMISATDFTTILGANAAPETQHALVEVIRCQGAVDMGLATSTKVAGLTRGTPKIALLSSPTHRANNKTPDIYVQSYSMGLPHPTLQLTGAVCLGSAVSIQGTIAADLSATPITDGPPTPERTPSPDMQGERKDTVNTRQIVIEHSKGTIPVLVKKNGEDGIESCAVSRTARRLFEGRVCYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5J9</accession>
    <name>X0C5J9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3500 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5J9"/>
    <dbReference type="eggNOG" id="ENOG502R8TZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033093_2_1_1"/>
    <dbReference type="OrthoDB" id="4539697at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021889">
        <property type="entry name" value="DUF3500"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489">
        <property type="entry name" value="DUF3500 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489:SF1">
        <property type="entry name" value="DUF3500 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12006">
        <property type="entry name" value="DUF3500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="49366" checksum="A8AACE3EC8DF45E9" modified="2014-05-14" version="1">MTSQSGSDGAFRQYLPDLNQPRFQNMKKQDSYEYADIFKKEGQPPWLHGLYLHWRNLFQEPYKGITNDGVVRDGLFELQDDGIPIDTIVEAADNLCANLSQDQKLKTCYHIDSPEWRSWSNPEFLLSDKGIRLDELSNELRSKALKVLELTLSPEGYKKALGAMRVNHFLGELVETPAIMNEFSYNFVLFGEPSTTRPWGYSFYGHHLCLNIFLYKTQIVVSPWFTGAEPNLIDDGPYKGTRILDREESLGLRLMQSLSPEQQKASQVYKLMKDPAMPHGRWNHDDQRHLCGAYRDNRIVPYEGILVSDMSNEQQDYILGIANEFFLYLPDKARKLRLELLKKWFHETYWCWIGGYGDNDPFYYRIQSPVVIFEFDHHSGVFLNNKEPAKFHIHTLMRTPNRGDYGMALRPLIPGIKQEFLWEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C666</accession>
    <name>X0C666_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C666"/>
    <dbReference type="HOGENOM" id="CLU_057894_0_0_1"/>
    <dbReference type="OrthoDB" id="5081728at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="384" mass="44071" checksum="375C2F047C65638C" modified="2014-05-14" version="1">MSALTNTQDAPSILNFPTLPKETILKILTEITQKNFSDYYTLIYTRDHTDCDGVFGQGQIESITLQHKCIYKAPVIDGEIDFLTPANLSWKLALEKNRVLHQLHVYDRYLNPDLVEPMRALWSRHNNPHPDLEAFRCDTGHLLVLTGDIMDDLPFAVDVYGGIDSPNRNAYVKKLHANDNRLECQRRGHIMICSSPWMVKDELPDEMEEHEYLISHFPDRLDANMHVAFHHALFHRRDADRLALLQLDWSLMTGLESLCLDLSGPWTDGPNAELKSFCVKMGSHLKLKTLVVLGLPVRQDYCKLGKDFWIKTLENQEYVPSTVVKSHFEDSDESDESDEGDEGDDDDSDDELVGFPTYIYWLKECLQPGSQVHSVMQYESETEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6X1</accession>
    <name>X0C6X1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Epoxide hydrolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979360">
        <property type="protein sequence ID" value="EXK78477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979360">
        <property type="protein sequence ID" value="EXK78478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6X1"/>
    <dbReference type="eggNOG" id="KOG2565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_0_1"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF39">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="3">
        <location>
            <begin position="21"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="407" mass="45866" checksum="504B98F02C2D0B02" modified="2014-05-14" version="1">MSSLPFSAPPWPIPASANLTSSTISIPDGEIEKLKTLLKLSPIPKANIWNSHEDGAFGLPRDTLTELVEYWANDYDWKKWEATLNSIPQFDITVTDDDSTDYKINFLALFSKKPSAVPILFLHSWPGSVVEYLPILQKLKSEYDPESLPYHIIVPHHIGFGFSDAPPLKKPFTHIDNARLMSKMMHSLGFDKTGYMTQGGDLGGWTAPVIANIDPACKLVHMSMLNISPPAGEDVEEGIKAGKYTPDEMAAFGRMAEFQKKETAFIHLDGTKPATAGYIFGSSPIALLAWIGDKMHRWSDETPDKDLILTNIALYWFTGCYPTSIYLHLTVLEDHELMMNAWKSLKVPLGHSAFKKELVTAPERWIQQTEQVKWYRMHDKGGHFAALEEPDALWKDVRDFIGAFWKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0C800</accession>
    <name>X0C800_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">F-box and leucine-rich repeat protein GRR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_09152</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C800"/>
    <dbReference type="SMR" id="X0C800"/>
    <dbReference type="eggNOG" id="KOG1947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10257471at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000251">
        <property type="entry name" value="Ubiquitin ligase complex F-box protein GRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050648">
        <property type="entry name" value="F-box_LRR-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382:SF67">
        <property type="entry name" value="SCF E3 UBIQUITIN LIGASE COMPLEX F-BOX PROTEIN POF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="68"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="575"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="690"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="718"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK87323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="742" mass="81433" checksum="F3C05A4CE8E8A5C0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C822</accession>
    <name>X0C822_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C822"/>
    <dbReference type="eggNOG" id="ENOG502SS3K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039196_0_0_1"/>
    <dbReference type="OrthoDB" id="5075616at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="62"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="537" mass="60658" checksum="5ABAD42199F3523F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9C2</accession>
    <name>X0C9C2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L44</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_06881</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9C2"/>
    <dbReference type="eggNOG" id="KOG3464">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114645_2_1_1"/>
    <dbReference type="OrthoDB" id="2967263at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.80:FF:000001">
        <property type="entry name" value="60S ribosomal protein L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK90696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="106" mass="12112" checksum="4285CAF587058C09" modified="2014-05-14" version="1">MVNIPKTRNTYCKGKECRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECVKCKTKLQLALKRCKHFELGGDKKTKGAALVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBF2</accession>
    <name>X0CBF2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBF2"/>
    <dbReference type="HOGENOM" id="CLU_3279490_0_0_1"/>
    <dbReference type="OrthoDB" id="10278545at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="41" mass="4179" checksum="47BD6A9EC65AB251" modified="2014-05-14" version="1">MPQQIRSMLELMAAVTTGSGLVNEPAAEDKIIFGSGVSATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDF5</accession>
    <name>X0CDF5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein NIS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDF5"/>
    <dbReference type="eggNOG" id="ENOG502S8NB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138726_0_0_1"/>
    <dbReference type="OrthoDB" id="3913322at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045469">
        <property type="entry name" value="Nis1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19271">
        <property type="entry name" value="Nis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939317" description="Secreted protein NIS1" evidence="1">
        <location>
            <begin position="19"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="14824" checksum="E850A89664A18E4A" modified="2014-05-14" version="1">MRFSIAAASAALLALAEARITGIKVPKEIAVGEPFEAIIVRENYIQSVFDSSIVFGYAPESQYPGTIGQVANSFALGKKESNKVEPLKKKLTIPEGATKGKGLVTAALLSIYGASGSPTISEYNVTVTFGDKTSKEYASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDK7</accession>
    <name>X0CDK7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDK7"/>
    <dbReference type="eggNOG" id="ENOG502RQK2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_816469_0_0_1"/>
    <dbReference type="OrthoDB" id="1689567at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="340" mass="37262" checksum="017311CC8B1ABD0A" modified="2014-05-14" version="1">MTLLSGDVRVYDQSSPFMEARDDYGQQQQHLGREQSPTQGITTSNIRDHYRPVPLGDGDHVLYTNPRTGTLSLGSDATGGSLDRLICKAQFRPPMNTTSTLPVLYTAVSDTRFGVCVMATFSVGSGYDSLGEDIFTRSINPDPSISSDTDKQMIVLYMISPDVLAVISHGLCRQHCMNATQHDENGSLLVEIDSRPKGSCNEIDSEGDSFAEVTTYPLEIRGLPVAICCNLVELALDSGADMILWAFCVQGWARAWALRVGHQDTPHRTVVEANGSLRQVDSKGDYNMTEEEQVVAAPDVSFKALTSAEIALKIKPDTTGQIPPTYEHGSLVIKIIFREW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE63</accession>
    <name>X0CE63_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE63"/>
    <dbReference type="HOGENOM" id="CLU_2776046_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="69" mass="7544" checksum="3AEA84845414351B" modified="2014-05-14" version="1">MSIEAEKAPLLAWLAKASVKGSLGRKSEEKEAIYSRYQEISGGHRLGVGGGTGCRGHFDWLPTLVVTRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFN6</accession>
    <name>X0CFN6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">COPII coated vesicle component SEC24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_05250</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFN6"/>
    <dbReference type="eggNOG" id="KOG1984">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004589_1_0_1"/>
    <dbReference type="OrthoDB" id="49016at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF4">
        <property type="entry name" value="SECRETORY 24CD, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="12">
        <location>
            <begin position="311"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="13">
        <location>
            <begin position="389"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="15">
        <location>
            <begin position="642"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="14">
        <location>
            <begin position="748"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="11">
        <location>
            <begin position="878"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK93016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1038" mass="113054" checksum="23D6BDB0E1815DB8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFX7</accession>
    <name>X0CFX7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFX7"/>
    <dbReference type="HOGENOM" id="CLU_2606114_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="79" mass="8848" checksum="A4342C4E19588AD3" modified="2014-05-14" version="1">MAKFGLVDASYFRAAPWGAKSLRHLQQNRAASSCLLSLLRWADAQGLKSPPPLLHHRCLHRITPPIRRGFSATWNNSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGW1</accession>
    <name>X0CGW1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myroilysin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658421">
        <property type="protein sequence ID" value="EXK81832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGW1"/>
    <dbReference type="HOGENOM" id="CLU_1806215_0_0_1"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939408" description="Myroilysin" evidence="1">
        <location>
            <begin position="17"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="14796" checksum="58CF75358652B551" modified="2014-05-14" version="1">MKIAAFLTSALAGAAAARDSVYLVNSYKGNEISSGIAYYADGHSATGGSRPDDYVDVVHGSNIIWEGQTVKGTFGSGVSFTSNIFADAAGKQGNAWAGTGTNGFHTYNCYKGTNPNGKPWVLYTVDGWTVNVIYFCNPFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIA3</accession>
    <name>X0CIA3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PRP1 splicing factor N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_06799</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIA3"/>
    <dbReference type="eggNOG" id="KOG0495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007010_0_0_1"/>
    <dbReference type="OrthoDB" id="440128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000649">
        <property type="entry name" value="mRNA splicing factor (Prp1/Zer1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:001164">
        <property type="entry name" value="mRNA splicing factor (Prp1/Zer1), putative (AFU_orthologue AFUA_2G06070)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000256">
        <property type="entry name" value="Probable pre-mRNA splicing factor prp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010491">
        <property type="entry name" value="PRP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06424">
        <property type="entry name" value="PRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13428">
        <property type="entry name" value="TPR_14"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PRP1 splicing factor N-terminal" evidence="9">
        <location>
            <begin position="12"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="699"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK90559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="930" mass="104462" checksum="2D08EA6A03D63CE1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIL7</accession>
    <name>X0CIL7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secondary metabolism regulator LAE1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIL7"/>
    <dbReference type="HOGENOM" id="CLU_010595_7_1_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="37301" checksum="62E0D3B9A8C1A7D7" modified="2014-05-14" version="1">MDHRDPEEDPTSDYGDSIATSEFTSVNTRELYSYEHGRRYQGFLCGRYGLPNDDAEQVREGLKHKLYLDYLLDGKLFLAPIGNNPQKIVDLGTGVGMWAQDVAENFPSARVIGCDLSPIQPHWTPPNVEFRVEDLEDENRPWTRIYDDADLIHVRALLQTLRKPRQLLERAFEKLKPGAWIEIHEIVPFVFSVDGTAGDDHPMNQFYRLVEGPFTTIYGWNLRFPFQIVEALRDVGFINVNERHSYTPVGRWHQEAKMREMGIFTQNILEEWVTAMLGRPDIMGVTEEEAYELGHSVFETFNNTRIHAQLDWIDCWAQKPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJI7</accession>
    <name>X0CJI7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12966</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJI7"/>
    <dbReference type="HOGENOM" id="CLU_017865_0_0_1"/>
    <dbReference type="OrthoDB" id="3163292at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF19">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="11"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK82692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="430" mass="48964" checksum="FD0CA60A19DAA1EE" modified="2014-05-14" version="1">MSSPSLQSANACIQCRRVKMKCRPMGQDTSKCERCTRKALDCIFREHRRGRKPGTKVTKTKKVPTISPQSIPSLESPAAAGAHISETEDDTNNLQPSGLLNHQALEGKFSLGNILSADQEPVQRQRSRNESLEDPIELGLITPSLAKSLFDSFITVLNPYISQLDPYLHTFTYVRSKSAFLLSSILAMSAKAFNHVLYAKLYDHSQDLFANVFRRGSKSIEIVQAILILTYWKEAQDTRVWTSVGYAIRICMDLGWHKLAHCGSAATTTETESQKRERRNIERTWYVLFVYDRSISLQTGRPWMIECSEFIELIEDWCNDPSAIDNDQLLGAFTTLRLVTSAAFPLLIDKSRQRSMSHNESAPLVRLLDGRIERWEKKWTERITAQTEQSCHEFLIRFYGTHLRLQLHTLPLHGILISGKSDINHHIDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJW1</accession>
    <name>X0CJW1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec39 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_06310</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJW1"/>
    <dbReference type="eggNOG" id="ENOG502R87S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006056_0_0_1"/>
    <dbReference type="OrthoDB" id="3434013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013244">
        <property type="entry name" value="Sec39_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40787:SF3">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40787">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08314">
        <property type="entry name" value="Sec39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738230" description="Sec39 domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="domain" description="Sec39" evidence="7">
        <location>
            <begin position="13"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="798"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="863"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="879"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK91578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="921" mass="101807" checksum="1AFA2926361E9F4D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKL2</accession>
    <name>X0CKL2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Hsp98-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_03721</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKL2"/>
    <dbReference type="eggNOG" id="KOG1051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_0_1"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000120">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="entry name" value="Clp, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="Double Clp-N motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="10">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="430"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK94980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="924" mass="103030" checksum="5678392B2ECBCFCE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKL5</accession>
    <name>X0CKL5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_06744</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKL5"/>
    <dbReference type="eggNOG" id="KOG4336">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026584_1_0_1"/>
    <dbReference type="OrthoDB" id="2193813at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08049">
        <property type="entry name" value="TAF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037818">
        <property type="entry name" value="TAF8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019473">
        <property type="entry name" value="TFIID_su8_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46469">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46469:SF1">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10406">
        <property type="entry name" value="TAF8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor TFIID subunit 8 C-terminal" evidence="8">
        <location>
            <begin position="85"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="72"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK91364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="217" mass="24650" checksum="EF538F4AAB607DB0" modified="2014-05-14" version="1">MIEAAKTLALAARREHPIPTDFEHALRRHNVSVSSLKPHLKPPVSKTQLFPGYVDVLPEDLDAYTTLPLLGEELSGQPDKDEKEYVPSSFPDFPSKHTYKFTPQEDTSIRDSKKIREEAARTAQQGEDALRRLVRASKMRKQKEVKNLVERDAHGKERFRLWESTMKRFMATEGRGENTDQMEIADHSMIVNGEALFSRKEVPKAGKRTAALAKKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLA5</accession>
    <name>X0CLA5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">E3 SUMO-protein ligase pli1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_06046</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PIAS family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLA5"/>
    <dbReference type="eggNOG" id="KOG2169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="28127at2759"/>
    <dbReference type="UniPathway" id="UPA00886"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16792">
        <property type="entry name" value="SP-RING_Siz-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.780">
        <property type="entry name" value="PINIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023321">
        <property type="entry name" value="PINIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038654">
        <property type="entry name" value="PINIT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031141">
        <property type="entry name" value="SIZ1/2_SP-RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14324">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51466">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PINIT" evidence="11">
        <location>
            <begin position="127"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="SP-RING-type" evidence="10">
        <location>
            <begin position="312"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="448"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="413"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="469"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="508"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK92098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="57908" checksum="4046B3C6677ED8BD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLU6</accession>
    <name>X0CLU6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLU6"/>
    <dbReference type="eggNOG" id="ENOG502RJ7Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1315461_0_0_1"/>
    <dbReference type="OrthoDB" id="5092327at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="209" mass="23468" checksum="BBE4A3CE188D746B" modified="2014-05-14" version="1">MNQPKGAGRAGGTILQAFLFLFTITNFFTLILNAATAGLYWDKQWGYIKALLVQGVYDEDYLSTAGSPDVFYTDVTSFEPGKFMKDSVRPYLLLAVVAGITWVIASIALLFLFTKIRHFNHRVARYVFRVIGVATFVFLVIFYLTWAHTYNFDFPFTLDWPLGKAAVIMAHINLLLGIFVTLLAAVLDTPKDWADHAPTGPNSRRTSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMN5</accession>
    <name>X0CMN5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Condensin complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_06043</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND3 (condensin subunit 3) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMN5"/>
    <dbReference type="eggNOG" id="KOG2025">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004446_0_1_1"/>
    <dbReference type="OrthoDB" id="27187at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000363">
        <property type="entry name" value="Nuclear condensin complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025977">
        <property type="entry name" value="Cnd3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12719">
        <property type="entry name" value="Cnd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear condensin complex subunit 3 C-terminal" evidence="9">
        <location>
            <begin position="615"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="558"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="952"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="577"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="971"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="998"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1012"/>
            <end position="1024"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK92094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1024" mass="113888" checksum="82F16CA95B54AC9B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMT0</accession>
    <name>X0CMT0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_06062</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Peripheral membrane protein</topology>
            <orientation evidence="1 8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small Tim family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMT0"/>
    <dbReference type="eggNOG" id="KOG3489">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141397_1_0_1"/>
    <dbReference type="OrthoDB" id="344165at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="9">
        <location>
            <begin position="26"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK92134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="93" mass="10796" checksum="FAB064EB2E23322B" modified="2014-05-14" version="1">MSAQQLSIDNADLEKLNDKDRLELRQFLANEQQRSQIQAQTHSLTQMCWTKCVPGNIKNPKLDKSEETCLANCVERFLDVNYLTMKHLNGMRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN37</accession>
    <name>X0CN37_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-hydroxyisobutyrate dehydrogenase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN37"/>
    <dbReference type="eggNOG" id="ENOG502RWEH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2624308at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="671"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="715"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="919" mass="103445" checksum="07E949AC44EB4EDD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN50</accession>
    <name>X0CN50_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_03124</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VPS53 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN50"/>
    <dbReference type="eggNOG" id="KOG2180">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10261632at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.110">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 53, C-terminus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039766">
        <property type="entry name" value="Vps53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031745">
        <property type="entry name" value="Vps53_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038260">
        <property type="entry name" value="Vps53_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007234">
        <property type="entry name" value="Vps53_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16854">
        <property type="entry name" value="VPS53_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04100">
        <property type="entry name" value="Vps53_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps53 N-terminal" evidence="8">
        <location>
            <begin position="15"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Vps53 C-terminal" evidence="9">
        <location>
            <begin position="610"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK95875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="826" mass="91874" checksum="D5D0AB497CB235BC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNT4</accession>
    <name>X0CNT4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNT4"/>
    <dbReference type="eggNOG" id="ENOG502SI2P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065434_0_0_1"/>
    <dbReference type="OrthoDB" id="5352400at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="287" mass="33276" checksum="84DE34664C9DB78E" modified="2014-05-14" version="1">MKFPTFKRSQQEHTDKPAKAKNYRVLFRKWPRVSRKGTWWLMPLELIGIVPALVIFGISQPNLYRTDMWQIGWEHDPPLNSNPARVLYAYANYQPQPKIALIWTRTFTNFNVAISIISLFFLLGKLTAFIMRVWYPIFATFINTSMVALYTVCVYGTIGPDYTDSRYPAPAAWYYRIGCDIAKPYGKYKSCMIARYSLVIGVYMLAIYLCNLAFSIYAMLPNKINDVSDDDDDEDGSTTSEPKGGVWEMHNMKTPSIRAMPYTPRTQAFHTLDRQLPLRSQQNRYYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP44</accession>
    <name>X0CP44_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Ent-kaurene oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_11556</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP44"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_3_1"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK84297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="55830" checksum="F3BB852B0E972FCD" modified="2014-05-14" version="1">MAILFSPLGLGVSLVAILIGAIIFVNKKTKFPIINKYPKDFFHRRANHEYKTNARKLLKDGAAKHGENPFAILVPNGIKTILPPSCVGWAKNNKDLDHQQLVRDEYFASYPGFDVQHVLHHPNRMVINMVQGKLSKTDKTLPVMNKHIKAGLSDIWGEDKSWKTLNWDDGTTGVISRAAASIFVGPELAADPEWQKVSRAYVLDYFGAVGEMHLWPSWLRWLVVWYLPGASACRAGLKRAREMVNKVVQKRRQEEQEAKLEGKEAPAYYDALAWTLESPLGNEFEPADVQLALAMAALFTTSELFRQILTEIARRPEVVEHLRREIEDAAPDHDFTATSLVKMQLLDSFMKETQRQIPSLVILERLVTHDTRLPDGTVLKKGTHIAIDSREMYDPSKFENPEEFDAWRFYKRRQAGDNASLFVQSSPEHAQFGMGKHLCPGRFFAGGELKLCLAQIILNYDIRLKDGCSGKPMQFGFLSATDPYTQLEVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP50</accession>
    <name>X0CP50_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_03310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP50"/>
    <dbReference type="eggNOG" id="ENOG502S2VB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021590_1_0_1"/>
    <dbReference type="OrthoDB" id="16772at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000323">
        <property type="term" value="C:lytic vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035493">
        <property type="term" value="P:SNARE complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF13">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="436"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="34"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK96190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="467" mass="52133" checksum="C251682726F9EB0C" modified="2014-05-14" version="1">MDCDICHRIHDTERLPFLCTVDARNSLLDGRINNVELLLQNESLQNEINELLDETSTPNKFHKESLQAQQRTAEDRTTQILAAADKLRNDIKAAREEIQARKAALSRRKSDIAAVSGGLVERRVKQQKDIETDIGRLKYKWSRSAGDMARTRSFLCMEAARLYGLERVKEGSTGKYEYHLGGIPVVDLATMNSSTPEMISTSLSHICHILMLVSHYLSIRLPAAITLPHRDYPRPTIFNLSASYRSGDPVFPSQAGVGNPSHSGDTESQRVSRPRPLFIDKPPALLAKEDPATFSYFIEGVTLLAYNIAWACSTQGVSIGDRTHFEDICNMGRNLHELLTNHQNVGGNLYPLSSNKKDPSASKNDTDAQASRMGQYSHGTTFYYLGGAEGTEFSKTFKLPGPMKLADKLKKKLLSEAPAPDWEVLDDDAWKVEEELVDTNQPNKDLLGSDKNSPRRGTSGWMKVKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQV1</accession>
    <name>X0CQV1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQV1"/>
    <dbReference type="eggNOG" id="ENOG502S9C7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_652175_0_0_1"/>
    <dbReference type="OrthoDB" id="5402897at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="421" mass="46016" checksum="350E370ACAF64BB2" modified="2014-05-14" version="1">MAASQNGGLVHQQLIPADSITASYDNEAKLLILKASGTHVDLTRDIEFRRLPFDGGLLFELIGWVGPVVHGESPYEITDSFNIDLPSIVFPSNTVVVNTENKQHWVVPIQYNKTTGQAATNGKAEVELPKVEQVSGDQKIVVLADEPFTIQQSDSFTGKGGSASIDFDKSFLTLTDARIDDGKIVWTFTAQQTGTTEVFVYVGQTQPPFLYRIPYVVESVVLDDKSVSTQTTASFSVNNNGQGSSGTYGAASNGHKNGNQKVGLPLSWDGFINVGLNLIKKQYPHANLLEVDATPLTRKPVQNEWGLVNNRIVCGLSGNKTAIIQSTGWGEFGKVQTINSPFLGDQVIPWPVTLDIHDAFTILRKAGYKQAIYAVTLRQPLYPGDDQPFYIFNTGTEFIAVGTKDKKIHNFGVSEYNVQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQW2</accession>
    <name>X0CQW2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05394</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQW2"/>
    <dbReference type="OrthoDB" id="2105077at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd13437">
        <property type="entry name" value="SPFH_alloslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF19">
        <property type="entry name" value="AT06885P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="88"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK93244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="355" mass="38379" checksum="19EB6816E7EE2880" modified="2014-05-14" version="1">MSSTEGMINGGSSSANPTKAPVMEGNGGFMAQHKMAVEPPKKEDLQRSYATVVENDANPKGWYGSMMNALGTIIGTMGAVPCCIICPNPFKEVNQGNVGLVTKFGKFYKAVDPGLVNINPLSERLIQIDVKIQTTEVPEQICMTKDNVTLRLTSVIYYHIVSPHKAAFGINNVKQALMERTQTTLRHVVGARVLQDVIERREEIAQSIGEIIEDVAAGWGVQVESMLIKDIVFSQELQESLSMAAQSKRIGESKIIAAKAEVESAKLMRQAADILSSAPAMQIRYLEAMQAMAKSANSKVIFLPAANQTMGNALNAAMANQTGESSARALDNENDFGGQDPGFQQAMNARVVENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT08</accession>
    <name>X0CT08_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02735</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT08"/>
    <dbReference type="eggNOG" id="KOG0195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_34_2_1"/>
    <dbReference type="OrthoDB" id="366390at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK97585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="156" mass="16584" checksum="5E890EB3E715F8D6" modified="2014-05-14" version="1">MSDASNQPARAGSLTPEMIEFASRMYDAARKGDVATFEQALPAGLPPNLTNDKGDTLLMLAAYHGHADLVKVLIQHGADPNRLNDRGQSPLAGAVFKKEDAVIQELLDGGADPEYGQPSAAECIAMFKQEDAWKSKFDGAPGKGQAGKTREAEGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU39</accession>
    <name>X0CU39_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Solute carrier family 25, member 46</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_03642</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU39"/>
    <dbReference type="eggNOG" id="KOG0755">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_14_3_1"/>
    <dbReference type="OrthoDB" id="6703404at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051508">
        <property type="entry name" value="Mito_Carrier_Antiporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928:SF1">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="2"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="107"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="208"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK94828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="310" mass="34047" checksum="9E0BCFAA4BE0D0FB" modified="2014-05-14" version="1">MSTTIGAFIAGGIAACGAVTATHPFETVKIRMQLQGELQNKGHQPHHYRGPIHGVSVIVRNEGVRNIYRGIGAAYIYQVLLNGCRLGFYDPMRNALASFFLKDGKAQNLGINMFCGAASGVIGAAAGSPFFLVKTRLQSFSAFRPVGTQHHYRGAWHGFKSIYGTEGISGLYRGVQAAMIRTAFGSSVQLPTYFFAKRRLVRHFDMEEGPGLHLASSAISGFVVCCVMHPPDTIMSRMYNQNGNLYSSVADCLSKTIRSEGLFALYKGFFPHLARILPHTILTLSLAEQTNKLVRKIEDRILPERLEMAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUM3</accession>
    <name>X0CUM3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09875</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUM3"/>
    <dbReference type="eggNOG" id="KOG4208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025741_5_0_1"/>
    <dbReference type="OrthoDB" id="21467at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12307">
        <property type="entry name" value="RRM_NIFK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46754">
        <property type="entry name" value="MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="145"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="295"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="333"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK86157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="369" mass="40754" checksum="1DC4B70C5AFD7AF8" modified="2014-05-14" version="1">MAPELRKRKSASDIKKPNGAAKAAQPKRKAPEDASPVSLKKQKSVKKTVVTKKAATKPAQKSKSKPEEVKVVEEETTTLDIPDESSESEAEEGKEVQAIVKELDSDDEDITEGDSSFKQGQDVGKIPKVSKDVQKAAKSSDEEAGVIYIGRIPHGFYEHEMRQYFEQFGPIVALRLSRNKKTGASKHYAFVKFEEASTAEIVCKTMDNYLLFGHILKCRMIPKEQVRDDLFKGANRRFKKVPWNKMAGHKLEKPLTESAWANKVTKENSKRAKKAAKLKELGYEFDAPEIKDVPAPAAIENGESETKAIEDAPAEKEEEPKVEEPAEVVETVVEEKTEVITEEKPAPKAKGKAAKGKAAKAGKGRKAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUW6</accession>
    <name>X0CUW6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">VLRF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_01208</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The VLRF1 domain mediates binding to the 60S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ANKZF1/VMS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUW6"/>
    <dbReference type="eggNOG" id="KOG2505">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014293_1_1_1"/>
    <dbReference type="OrthoDB" id="429841at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047139">
        <property type="entry name" value="ANKZ1/VMS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041175">
        <property type="entry name" value="VLRF1/Vms1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036">
        <property type="entry name" value="ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036:SF2">
        <property type="entry name" value="TRNA ENDONUCLEASE ANKZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18826">
        <property type="entry name" value="bVLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52044">
        <property type="entry name" value="VLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VLRF1" evidence="13">
        <location>
            <begin position="274"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="512"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="152"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="437"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="576"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="589"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="642"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK98235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="682" mass="75797" checksum="CFF517A4D9BD3C2F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV02</accession>
    <name>X0CV02_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">NADH-ubiquinone oxidoreductase B12 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_03821</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB3 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV02"/>
    <dbReference type="eggNOG" id="ENOG502SBXP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145518_1_0_1"/>
    <dbReference type="OrthoDB" id="521512at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012576">
        <property type="entry name" value="NDUFB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08122">
        <property type="entry name" value="NDUF_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK95148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="11000" checksum="71CED55F3D4966D2" modified="2014-05-14" version="1">MLATRVLRAAAGGPKPNITGFNMRAFQASTGQPRYDPWERNEAWRYQGPYTRWNRLKSGFPGLGIATVAFTAYCGYEYFFLEDEHHHGEAHGEEHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV82</accession>
    <name>X0CV82_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV82"/>
    <dbReference type="HOGENOM" id="CLU_3377131_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="34" mass="3916" checksum="34A582604060963A" modified="2014-05-14" version="1">MACINSETIESFQTILPLTSFNYEHMQQQLGNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CX51</accession>
    <name>X0CX51_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_04015</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.67" evidence="1"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CX51"/>
    <dbReference type="eggNOG" id="KOG2283">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020105_4_2_1"/>
    <dbReference type="OrthoDB" id="16692at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042995">
        <property type="term" value="C:cell projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016314">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043491">
        <property type="term" value="P:phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051896">
        <property type="term" value="P:regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14497">
        <property type="entry name" value="PTP_PTEN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051281">
        <property type="entry name" value="Dual-spec_lipid-protein_phosph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029023">
        <property type="entry name" value="Tensin_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305">
        <property type="entry name" value="PHOSPHATASE WITH HOMOLOGY TO TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305:SF81">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51181">
        <property type="entry name" value="PPASE_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatase tensin-type" evidence="5">
        <location>
            <begin position="12"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="130"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="291"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="477"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="530"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="558"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK95444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="570" mass="62880" checksum="F9E5D263939541BD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXJ3</accession>
    <name>X0CXJ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_01636</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXJ3"/>
    <dbReference type="eggNOG" id="ENOG502SAHY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019472_1_0_1"/>
    <dbReference type="OrthoDB" id="4117572at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF1">
        <property type="entry name" value="PROTEIN PACG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="85"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="85"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="308"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="407"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK98896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="529" mass="58093" checksum="EA5D7601583C7012" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYM7</accession>
    <name>X0CYM7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Trichodiene oxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_08913</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYM7"/>
    <dbReference type="HOGENOM" id="CLU_001570_14_4_1"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK87572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="57339" checksum="E8C19335B17CB4FA" modified="2014-05-14" version="1">MENLQLNARTLLTVAASLIALRITYTVVYRLYLSPLAKIPGPRLAALTFFYEFYYDVIKRGKFLWKIQELHRQYGPIVRINPYEVHINNDSFYDEIYASGPHHPRNKVRFMSTHDESMFDSYAAETHRVRRAALSGSFSKQSIRALEPQILQTIHQLASRMSSLRESGEVVNLKALYSGLTMDVIAQYCFGESMDNMKQDQFGKELLDFFHEMPQAHPIGRMFPWLFDIIQKIPISYLAKLDPKLQPLADYDKKISGQISDVLAKEKKDGIRTVFHEMRDSKQLPEADKTLERFKSEAAIFLGAGTETTAAALTALSFHLTENPDMLTTLRKELETVTGDASSPITVAKLEPLPYLTGVIQEGIRLSFGVPGRLPRYAPTEDLVYAGYKLPRGTRMSSSSYLIDTNEEHYPDPFKFDPERWMHGKTSLSRHFVPFCRGSRQCIGMNLAYAELYLTVATIFSRFDLELVGTTKRDVEIAHDFFVGMPPLDSKGVMVRVVKDRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYN2</accession>
    <name>X0CYN2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1275 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYN2"/>
    <dbReference type="eggNOG" id="ENOG502RR78">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061825_0_0_1"/>
    <dbReference type="OrthoDB" id="5288586at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488:SF1">
        <property type="entry name" value="DUF1275 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="29658" checksum="A7184CEDE25C492A" modified="2014-05-14" version="1">MVRAVDRGVRNTVVRDEETPLLGSSLSRPQKKSWKERLQHDVSCSWADAVLLACYVVTGLLDSSSIQVWGTFVSMQTGNTVYVGLGLASFATSTPGPRLYKSALSIASFCLGSFLFARFHRLVSPRRRWVLCASFTIQALLTSAAALIVTLRPPGPNTDSLAWNVLVPIALMAFQSCGQAVASRALKQNALISLVLTSVYCDLFSDKELFALDNVSRNQRAAAPTLLLVGVIAGGLFAQSSVGIAGALWIAAGLKLCMVIAWFLWRSEEETEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYY2</accession>
    <name>X0CYY2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYY2"/>
    <dbReference type="eggNOG" id="KOG1408">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005113_0_0_1"/>
    <dbReference type="OrthoDB" id="6252103at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052779">
        <property type="entry name" value="WDR62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589:SF1">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="979"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="808"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1019" mass="110854" checksum="0A940F1C0383AD31" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ85</accession>
    <name>X0CZ85_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">L-asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01999</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ85"/>
    <dbReference type="HOGENOM" id="CLU_062004_0_0_1"/>
    <dbReference type="OrthoDB" id="2588474at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010349">
        <property type="entry name" value="Asparaginase_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42110">
        <property type="entry name" value="L-ASPARAGINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42110:SF1">
        <property type="entry name" value="L-ASPARAGINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06089">
        <property type="entry name" value="Asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="360" mass="38926" checksum="F3A771DED43E3054" modified="2014-05-14" version="1">MIIPQSAEHRDCVVSDRGGIVENTHLIHVAVTDASGQILFAVGNPTRITLARSAAKPIQILALLETKGFEKFGFSDADIALMCSSHSSEESHITRGTEMLVKVAASEKDLRCGGHPALSEAVNRDWIMRDFVPGALCNNCSAKHIGMLAGAKAIDPENAEYYHEGDHMMQLCVKAVFEEVAGLESKDIKWGIDGCNLPTPALPLQDLSYLYAVLADAADSTKGTDSLESGRKEKLARIYRAMWQYPEMVAGQGRFCTELMLQYKGGLVGKLGADGCYGIAVKESEQTRNLGARGGLGIAVKVEDGDSEILYAVVVEVLERLKVGSSKQLENLDVFHHLTRVNTAGVVTGKVSLDFRLNSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0D054</accession>
    <name>X0D054_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">AAT family amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_08498</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D054"/>
    <dbReference type="SMR" id="X0D054"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_0_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000017">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004762">
        <property type="entry name" value="Amino_acid_permease_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00913">
        <property type="entry name" value="2A0310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF1">
        <property type="entry name" value="GENERAL AMINO-ACID PERMEASE GAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="453"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="10">
        <location>
            <begin position="100"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK88072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="603" mass="65884" checksum="59E9AA5B6762DE21" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0A2</accession>
    <name>X0D0A2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00444</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0A2"/>
    <dbReference type="HOGENOM" id="CLU_2885829_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL00171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="63" mass="6628" checksum="F09FA5D0C7BBBFE3" modified="2014-05-14" version="1">MTNSGGCTNGLPKDVGGRTMWPVKRGPGAFLSKQITCWRGIIGDSIKALLDHGEVGVLALCDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2D5</accession>
    <name>X0D2D5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2D5"/>
    <dbReference type="HOGENOM" id="CLU_1482046_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="182" mass="20170" checksum="13C862C5484396AA" modified="2014-05-14" version="1">MSLRPSINLTRRCLFSLSSTSRRTFAQQARQTRPPPPPPFQTVATCPEPTCGCAATPAMPEDLPLDREGPLKGAIAGYAEHVLVCTGNADWPSRIEDDNGGDCLAADLKELFGRGGTYSDVGFLLLCVDCLADSCSLFIIFLFSTRRFRALFHHVLKFKPHPCIWFQASNTSLFYRGYHLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3U5</accession>
    <name>X0D3U5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="6">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_00950</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="6"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3U5"/>
    <dbReference type="eggNOG" id="KOG1232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_4_1_1"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2190:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="8">
        <location>
            <begin position="126"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXL01087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="558" mass="61405" checksum="1135085E45A5BA48" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0D468</accession>
    <name>X0D468_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D468"/>
    <dbReference type="eggNOG" id="ENOG502T02S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036637_0_0_1"/>
    <dbReference type="OrthoDB" id="2446291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="305" mass="33962" checksum="8271A20608E7EB9C" modified="2014-05-14" version="1">MFAVQHAGFDQRKRVREEEELANANGMSFSEHRNKRIQCLPLRAYPRTTQQWQPDAPMPAPSFAPHDHLQPEIRQWSSSTNMTSQSHGDTDMDMMQTYQPQHHEQGRLGVMHQESDNANGRLPTPIQPSFAAQVRGQQAVTTPNGVANLGHQNTGFGDDQSVPRTMAGGWQAIQNERRLPSPISEGDDSMACQPITPTGMQFDASAHGFVTPGMEHPNVTVEPSPPHDVEHPMMDVESHCSGNSVDGDGDPTTPSPRRGHIRSRHTVNNWTWQPGMKKSFSIGYRADCEKCRLKVPGHFNHIIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4E4</accession>
    <name>X0D4E4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4E4"/>
    <dbReference type="eggNOG" id="KOG1552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029375_3_0_1"/>
    <dbReference type="OrthoDB" id="446723at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="160"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK98004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="428" mass="46647" checksum="274453E4CE3BC5E7" modified="2014-05-14" version="1">MVELCYVLTSLDLSASIDTSEPSRLYPITMVAFSVLRPTMLALGLTLGLPAILYFSILGALVVAPSLQAHAIYLHKVALTWFKDLNTPEQFGFAHHQVTPFYISTPDGVKLHTWHVLPLAAYESHQEELLAQGPDGGLVDKFEETLNFRQLKESPNARLVLYFHGTSGTMASGWRPDSYRSLYSADPVNTHVLTFDYRGYGESTGSPSEDGIVMDAVTVANWAIHTAGIPPEGIVIFGQSLGSAVAIALVNELAHRQPSVHFAGLVVTATFADIPQLTATYRIGGFIPALAPVAKVKPVFAFFARQLSSTWDNMYRLGEFVKAAERYDIALLHAEDDTDVPMEHSVKLYREAVRAAEGLKDLTENEGALLSRISSVEKGRGAGGSITVWPTSKGNIRLEILKYGAHDKIMAYPATGLAINRAFASVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0D529</accession>
    <name>X0D529_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D529"/>
    <dbReference type="eggNOG" id="ENOG502S8II">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125080_1_0_1"/>
    <dbReference type="OrthoDB" id="2989864at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025363">
        <property type="entry name" value="DUF4267"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14087">
        <property type="entry name" value="DUF4267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="134" mass="14644" checksum="264955FD96A27905" modified="2014-05-14" version="1">MASGLFSNVSPWHIPAMFMGTAFTLGGLLPLRAPDRAMREYGLPEGIVRSEPAQLAFGIYGTRVAAYGVALWTFYLRGEYHVVDTLMSLLFLWGAADCWICIKAGVPRTAVWRFVSSIMIGGYGYLGLTTKGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7B8</accession>
    <name>X0D7B8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7B8"/>
    <dbReference type="HOGENOM" id="CLU_035264_2_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="130"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="345" mass="38457" checksum="452676A2816A432C" modified="2014-05-14" version="1">MIMSYHHLEELCSGQGDEISLYIRWNDARLLVYLNRCPLSHVVPPVENSFIDRYNQACDSDDIEEAEALSDEILDAVVEAGRDEFDRLAPPSASGKTSSQGLHTLLFPKEYYFSFRTLNGKAEVLRQDSGVKQDAVLVGQSGLPFHLNKDKDCNLPIYSTKDIHVVEDLRNASSIAHVMVDGKEMCSKVGDSKGEDSAQRELDCLWKITTSPHAAAIQVPKILGLITIPENGKTIGFLEEYIPVSETWELSTLGSIEDVSAIDESRRKKWASQVRDNVDLLHKTGITWGDGKASNVLIHRETDDAWIIDFGGGWTEGWVDKPLSGTIKGDKMTVKKIFGYLQVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7W9</accession>
    <name>X0D7W9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_06882</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the COPE family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7W9"/>
    <dbReference type="eggNOG" id="KOG3081">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049363_1_0_1"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000613">
        <property type="entry name" value="Coatomer subunit epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006822">
        <property type="entry name" value="Coatomer_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805:SF0">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04733">
        <property type="entry name" value="Coatomer_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016478">
        <property type="entry name" value="Coatomer_esu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK90697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="294" mass="31834" checksum="62E3A977EE416D65" modified="2014-05-14" version="1">MDPYSTEGELINIHNHFHQGQYQEVIDFDTSSFSPDNALPARILVLRARLALGQAEDVLDDVKGNSQPELQALGALAEFKLGKADSAVQTIEKLASSAADNTTVQVIGGTVLQAAGKSEEALALLTQHQGSLDAVSLIVQIHLQQNRTDLALKEVSAARRWAQDSLLVNLAESWVGLRVGGEKYQQAFYVFEELAQAPSTSSIRSLVSQAVCELHLGRTEEAQAALEQALEKDANNADAIANLLVLNVISGNQSDEFAQKLRSVKPDHQFLTDLEEKSALFDKAATKYSPKVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8Q1</accession>
    <name>X0D8Q1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8Q1"/>
    <dbReference type="HOGENOM" id="CLU_2084937_0_0_1"/>
    <dbReference type="OrthoDB" id="5292533at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="117" mass="13352" checksum="567979A5F6B18475" modified="2014-05-14" version="1">MLCEWFTHEQTGATKAIEYIKTHKTQSGVDNIFGAKSSTVPPVDSQKRKIIGHFNGFPRISEDMQSPFQAEREPLLRYALVAAVTGCKLYIGYFKNKRRELKEALEVNPTRNSTIYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBG7</accession>
    <name>X0DBG7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_05915</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBG7"/>
    <dbReference type="eggNOG" id="ENOG502RVTU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011099_5_1_1"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF25">
        <property type="entry name" value="ABC-TRANSPORTER-REGULATING TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK91912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="671" mass="75624" checksum="74B053DABC202762" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0DDP6</accession>
    <name>X0DDP6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="10">1.3.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">FOQG_01022</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="17">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.88" evidence="10"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DDP6"/>
    <dbReference type="eggNOG" id="KOG2335">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_5_1_1"/>
    <dbReference type="OrthoDB" id="272303at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="19">
        <location>
            <begin position="37"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="333"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="424"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="471"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="481"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EXL01210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="511" mass="57661" checksum="3AF4E7F37226A835" modified="2014-05-14" version="1">MSTMTTTEENPTSAGEHPTKLQGRAFYESIGSPKFIVAPMVDQSEFAWRMLTRSFISPTEQKSLLAYTPMLHARLFSQDEKYRKAHFQSVKSDGETPWLDGNPSIDRPLFVQFCANDPEALLSAAKQVAPYCDAVDLNLGCPQGIARKGKYGAFLQEDQDLIFRLINILHKELPVPVTAKIRILDTKEETLAYAQNVLKAGASILTVHGRRREQKGHLTGLAEWKMIRFLRDSLPRETVIFANGNILQEGDIEKCLEATGADGVMSAEGNLSDPAIFTKPPAVGEEGREYWRGKDGKGGYRVDAVFRRYMDILHEHVFGEKHIERRPLFMPGDDTEWMNESETVEDEPPSKKRRKDLGKKGEQGPNMSAMQPHLFHLLRHFVSKHTDVRDMLAKSRAGDMEAYERVLSAVERKVAEGLIEYERTNGESVAETPLAEGEEDPPETESSVGTQRRCRRPWWVVQPIIRPLPNEAFKKGALTMSKKDKVKAQEQKQEEKGKQEDIKARDEALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0DLY1</accession>
    <name>X0DLY1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03962</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DLY1"/>
    <dbReference type="eggNOG" id="KOG2820">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_0_2_1"/>
    <dbReference type="OrthoDB" id="2219495at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051698">
        <property type="term" value="F:saccharopine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF26">
        <property type="entry name" value="L-SACCHAROPINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="6"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="433" mass="48379" checksum="907FD86C3742D7C1" modified="2014-05-14" version="1">MSKPSVLIIGGGVFGTSTAYHLIQRGYTNVTVVDRFAAPSRDSAGTDLNKVIRADYPNPYYAQLGLETLGVWKDPDSLFKGLYRESGWIMGGHEETNQWLENAKDLAEKKGRQGVEYLDVERIREKWPALTGEFPGWTNLYSPQAGWVPSGQALLRMAKAAEKNGAKYITGHAGQIKELVYEDGTCKGAVAANGEIHRADKVIVAAGAGLPALVEGARTDVRAETSVICVMKLEPHEIEKYKDIPIIDDFEQGIIFPPDENGLIKLCSVRLVTNYFNHVHSGASVLHSVGDYPFDGCPRELEVEIRKFVREMIPELADRPFVHTRQCWDGMASDLNFRICPYPDTKNLYIATAGSNHGFKFLPIIGKYVVDLLEDSLDSGLKNLWSWKFGKKPDDFQDPHPFPRRDLNELTGWKGRNAPADGKLPWTWSRSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0DMS7</accession>
    <name>X0DMS7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DMS7"/>
    <dbReference type="HOGENOM" id="CLU_2277661_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="102" mass="11566" checksum="EA89DE4C9AA6AB12" modified="2014-05-14" version="1">MTGREATEIPMVASRDNRLVLSRMSPVSLEKAGGTGSRRLRSSRALDEKYPMLLVFRPRSSSRVTLQHTDRPDQLTDASFEENQPPLLVPERQLLVRGRDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0DR95</accession>
    <name>X0DR95_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DR95"/>
    <dbReference type="HOGENOM" id="CLU_2885839_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="63" mass="6801" checksum="17E0821E6B915308" modified="2014-05-14" version="1">MGSVAHTVFFHFLLRHPFSGFSSAESIKVDRINTTPLASKCSAGLLVDSEYGSAPQWTNNSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0DRH5</accession>
    <name>X0DRH5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DRH5"/>
    <dbReference type="eggNOG" id="ENOG502RK0Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060983_1_0_1"/>
    <dbReference type="OrthoDB" id="3012298at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06546">
        <property type="entry name" value="GH18_CTS3_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF60">
        <property type="entry name" value="III CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="2">
        <location>
            <begin position="12"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK96877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="344" mass="38091" checksum="1F600F17EA0C30EF" modified="2014-05-14" version="1">MPPLPPSANPLPRLITYYQTHHDSSGNLISPLSLITQPGIAITHVIVAAIHINDDPQKITLNDYHPSHPIFQTMWAELRVLQASGVKVMGMLGGACKGSYARLDADQETFDRYYGPVKDMIRERGLDGLDLDVEEEMTLGGIVRLIDRLRSDFGPAFIITLAPVAMSLLDFTKNLSGFDYEALEVMRGRDIAWYNTQFYCGWGDCSNPLMYDLMVRKGWPPEKIVIGLVTNPENGSGYVPMNPLNMVLTTLRGRYGSFGGIMGWEYFNSLPGGKERPWEWAREMTKLLRGHLLSAPAQATQPVLPAAVESGSKAKNEDVDPDGPGGQDAPVPKQFEYYSDGLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0DSQ9</accession>
    <name>X0DSQ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_02541</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DSQ9"/>
    <dbReference type="eggNOG" id="KOG0147">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020551_4_1_1"/>
    <dbReference type="OrthoDB" id="5411533at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12283">
        <property type="entry name" value="RRM1_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12284">
        <property type="entry name" value="RRM2_RBM23_RBM39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12285">
        <property type="entry name" value="RRM3_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000876">
        <property type="entry name" value="RNA splicing factor (Pad-1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000172">
        <property type="entry name" value="RNA splicing factor Pad-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000354">
        <property type="entry name" value="RNA splicing factor Pad-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029123">
        <property type="entry name" value="RBM39_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006509">
        <property type="entry name" value="RBM39_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01622">
        <property type="entry name" value="SF-CC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48036">
        <property type="entry name" value="SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15519">
        <property type="entry name" value="RBM39linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="178"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="277"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="469"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="374"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="131"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK97292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="566" mass="64791" checksum="B33657AE98A6AE80" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0E0B9</accession>
    <name>X0E0B9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_00187</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E0B9"/>
    <dbReference type="eggNOG" id="KOG1725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK99782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="169" mass="19147" checksum="2B2255A727567684" modified="2014-05-14" version="1">MSAQDKAQQYLGQLDRELSKYPALNNLEKQAGVPKAYAAIGVGALYFFLIIFNLGGQLLTNLAGFVIPGYYSLGALFTHNKEDDTQWLTYWVVFSLFTVIESFVQVVYWFPFYFVFKFIFLLWLSLPAFRGAELIFRSFLAPTLGRYFQQTGSTASGLRAKADGLDKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0E0L1</accession>
    <name>X0E0L1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall proline rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E0L1"/>
    <dbReference type="eggNOG" id="ENOG502RD9J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007264_0_0_1"/>
    <dbReference type="OrthoDB" id="5406427at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="839"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="775"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="800"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="839"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="869"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="912"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="931"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="940" mass="100828" checksum="326168FA1055926B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B141</accession>
    <name>X0B141_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979782">
        <property type="protein sequence ID" value="EXK75830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B141"/>
    <dbReference type="eggNOG" id="ENOG502RKQR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1885888_0_0_1"/>
    <dbReference type="OrthoDB" id="5064746at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="135" mass="15368" checksum="D3C57967D43F6D7F" modified="2014-05-14" version="1">MQCDQGRLDSRNFLSRGHMVALAEEYEKRIASHGTRHVSSAISAWMQLDAGQDGQSHGPLRDLIIDEMTRELYALDTHYKFNPQDRKKKQIESWIHAGRLLLALVKEMGWGAMLVPGFQLTNDEYVSDLNLTLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3Q9</accession>
    <name>X0B3Q9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979452">
        <property type="protein sequence ID" value="EXK76740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3Q9"/>
    <dbReference type="HOGENOM" id="CLU_871669_0_0_1"/>
    <dbReference type="OrthoDB" id="4525715at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="273" mass="31079" checksum="FF057C6C0E31CFBF" modified="2014-05-14" version="1">MTLPLDHRYAADPDVRNRPASSISLQYPDGTPSLPEPTVLLTEIQKAADDVEQLVGRFGHKMANRLTYPTVKAALFSDHDKLQLSSLGYADNFTCRYTRSVGQIDCFSKNGFPLLWWLWDALLEFFTASDRSKGFILEFASAKRTDVDLPYTIRLKLWSDQGTKKIELTAAYGEPYNAGYEAMFKYIMPRPDSIWCRAMSTSEEHEETLVKNLAEARKSNNDRPSISDAQDLQCKSLADRFPEEAREFVETNVLVREEFKITNGVLLKGRTIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6A4</accession>
    <name>X0B6A4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979398">
        <property type="protein sequence ID" value="EXK77291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6A4"/>
    <dbReference type="HOGENOM" id="CLU_2004013_0_0_1"/>
    <dbReference type="OrthoDB" id="5055660at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="124" mass="13828" checksum="2AA761ADD14C5372" modified="2014-05-14" version="1">MPSSTSAQATTIAEGKPKSAAFRHQNTRFPVRVDPAKLLERKIIWFANGFPGNQLPGRLEAAVEKAKLQQPNWERYADKGEEWPSEWDMNEGDALSDAITQVLNAPLCDGVTVEWLGQMRSIDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0B703</accession>
    <name>X0B703_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_17381</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979373">
        <property type="protein sequence ID" value="EXK77915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B703"/>
    <dbReference type="HOGENOM" id="CLU_004981_0_0_1"/>
    <dbReference type="OrthoDB" id="18797at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32114">
        <property type="entry name" value="ABC TRANSPORTER ABCH.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32114:SF2">
        <property type="entry name" value="ABC TRANSPORTER ABCH.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="9"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="4">
        <location>
            <begin position="484"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="348"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="673"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="839"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK77915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1148" mass="127303" checksum="7B25F1FAF5810DC7" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAJ3</accession>
    <name>X0BAJ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FluG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658503">
        <property type="protein sequence ID" value="EXK78781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAJ3"/>
    <dbReference type="OrthoDB" id="4485682at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021842">
        <property type="entry name" value="DUF3435"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535">
        <property type="entry name" value="FLUG DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535:SF3">
        <property type="entry name" value="FLUG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11917">
        <property type="entry name" value="DUF3435"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="813" mass="94296" checksum="4D669BBC0FCA2CD0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAV4</accession>
    <name>X0BAV4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinetochore protein mis13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658781">
        <property type="protein sequence ID" value="EXK75953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAV4"/>
    <dbReference type="HOGENOM" id="CLU_021697_1_0_1"/>
    <dbReference type="OrthoDB" id="3364649at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013218">
        <property type="entry name" value="Dsn1/Mis13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778:SF2">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08202">
        <property type="entry name" value="MIS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK75953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="56041" checksum="2EB593EB21E22841" modified="2014-05-14" version="1">MRNEHGRRLSKRLAAAAATDYEHDDGFAFVRKSKRIKTDMTDEPKPEAVPEPKAEPVKKSAKGRPAAKQRAAKAPTTNGTIMEEEPPEQGTSATTKPATRKSSRRKAIVDASDEREIKVPKRPSTSRSTRRSAEAQEKEASQPAPSSIPEPEPEPQPETVPEAAPASRVNGAPKKRGSGAKPTRQPPDWDNSPQREPPVQSATITLPMSDTPIINRNKEMRKKGGNSNRRSSLSNRGRRASSLIESGQTAIPHREVNPADFYKHIEAEGLTEPRRMKQLLTWCGERALAGRPPHGTPNSNAILGARAIQDQLPKDFAARSEFSDWFNREDDGPNVPVVLRPNPRNMELDEKLAQLEINIKRLQDEKKAWQAIRKPPPEQPPLFSEGETGPIVLPDFDLLDPDEGKIRAFLADETASFDTIRSQTGSRLRTIQSSLEFQVDQLTYNIHRLEQRILVAGKEANNVLSVSALRLRQREEREKASAGTRDMPVIEVLRSLGNIRPEGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC99</accession>
    <name>X0BC99_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979505">
        <property type="protein sequence ID" value="EXK76448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC99"/>
    <dbReference type="HOGENOM" id="CLU_1660831_0_0_1"/>
    <dbReference type="OrthoDB" id="5426765at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="159" mass="18117" checksum="74093E5C1C0F4833" modified="2014-05-14" version="1">MLHCKDSKLRENGNQAESYPDPTHPANKLQYDDTEKDAWFTIPLSSPSSTGATPPFLASPSVNDSKPTLKHTKLCRRRYLLCFIWLSAVLIYIAIEWFDLLKSADSIKLLAWKHRDDYALSLHFKFSQVFLQYYFKVLKLKASSSTTPGNGHWGTSDMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCP2</accession>
    <name>X0BCP2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18668</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979478">
        <property type="protein sequence ID" value="EXK76593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCP2"/>
    <dbReference type="HOGENOM" id="CLU_052452_0_0_1"/>
    <dbReference type="OrthoDB" id="3927840at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="377" mass="42991" checksum="B9607BB0C8CE6B77" modified="2014-05-14" version="1">MMFEPLSSGATGKDMERLKAVASRVRSLSLVLRGNFELKHWYLLQHLTNLTHLELHGSHEFLGWNYLYQENESTLLEQLDLPSAGRSTLRHVKLYGYIPRCLAAWVLKTGVNLERLELGMLEGGVEIEDPASGHRRRGEPWTPYHFYPANMMRVQNQEWLPIPRPLSCFLPSEVQKDQALGFSLPRLKHLHLCQPSRGDDAIAEDMLYYWSVRTERPAHKSWREIVVASRLTLETLVLEQRIGVQEHARKQDSEVFIQPDPSGIGSEKLLDMVGKLLTHHDFPALKHLELRGMFVSAGKDDYPVSGSPVGDFMLLMRKNCVKCEARRGCMCWFDGDYGGAEWDAWKTDLKNEAGIRAEQRGEAVVTELNSEELLASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDN2</accession>
    <name>X0BDN2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979430">
        <property type="protein sequence ID" value="EXK76933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDN2"/>
    <dbReference type="HOGENOM" id="CLU_750149_0_0_1"/>
    <dbReference type="OrthoDB" id="10315841at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="369" mass="42056" checksum="92F805E67F96EE47" modified="2014-05-14" version="1">MTRQRARSKTTSQDDITKQRKREAKKDQAKARREERMKCREKAGKKRYAAALKAVERAEKGNLLNDCTYHAKPFHQYIAQSRYETRTPFFTGLSIKSIVRLARSFKFQEWQIIEQQQDWLNRVMPVVEANATNLENWFVFWSSIHASNIQWGNCVLVEITCDLFKGSTADLVDSVLCVSKGALPEIKDNSSDDQVETRLLSQQTPSQNIEPPATTLSGSASSWHTTVLEPVPITETEVAAWAKSQLSQYIKDNFQDDPGTIAALHRRITNLGREYVLDLHSIMTGAPGLNTRNMKEIFLRAWGEMENSDGFQLERLLGLSRTVCLAMKIAHKGDYTLELKVPRNAALMIIKEFRPHLHVDPLDSSFVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFI8</accession>
    <name>X0BFI8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18074</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979405">
        <property type="protein sequence ID" value="EXK77214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFI8"/>
    <dbReference type="HOGENOM" id="CLU_2497996_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9142" checksum="0BACA7526F83AE8C" modified="2014-05-14" version="1">MVGIGGAAPANKDIRLGDIVVGTRVMQYDLGKILSGGEIQRTAIPKTSDQSLCTAVTKVRILIGAAHLWSTFLSRAPIRIEVQAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFJ8</accession>
    <name>X0BFJ8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658589">
        <property type="protein sequence ID" value="EXK77613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFJ8"/>
    <dbReference type="HOGENOM" id="CLU_953148_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF6">
        <property type="entry name" value="FORMYLMETHIONINE DEFORMYLASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="304" mass="33577" checksum="F5FADBED0B1B6894" modified="2014-05-14" version="1">MDVRFQDQESSGWKNISCVTLEARYNATVKYTENTQAINFTVTPGPPLNATEIGRGELFYDARVTDDRYGILQPSNDSPYRLEEEELNSVYRRLQIRAIQESLAFSLAGAISDFGHENWFTVNTIIASTLFATPQYDPRERTFSTLKFNLTPQMLEELMHNVTLSLFNRATNLTLVNVITEPYEQAYVFQYPVRLIGPYAAILVTALCAVVYGLLALVRNGVAATSGGFLQVLCTTTNGNSLLNQIAAGACLGGNESIPPELGKMKILFGEVRDEESQAGLRKRAAFGTVNETVPLMKGAEYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFM2</accession>
    <name>X0BFM2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17671</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979380">
        <property type="protein sequence ID" value="EXK77633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFM2"/>
    <dbReference type="HOGENOM" id="CLU_001103_21_2_1"/>
    <dbReference type="OrthoDB" id="5244177at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF154">
        <property type="entry name" value="RECQ HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="315"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="470" mass="54101" checksum="3282268B8D09099E" modified="2014-05-14" version="1">MNGGVRNIFIHEGMVCFVTMYHKGFRQTGNTKIIHRYVPREVGELLVWYMWLVLPFWQNVQGRLKRKRRRSAFLWADEVVSEEGGKEGKIREVKVRAQDGGREEAVRESLGAGGEYEEDEEEEAAFMEWFREKKWTSDRVRRVIQRYSTEFSGHEINISAWRQMAIGISNRYFNKVFSIDDNSGDFEEEDSEEGSGNLVNSIEDLQAGHGSHVAGLIYARLFGQGDLGTMREREEFRKVSMRWHRFFDFGAEDRTDQFGSMSGGLKRKKEAFDDEREMMRRKRFDRLHRIDIKGQLRQMMGPTAMFRGLQEKVIRAVARGEWPIVQVTPTGGGKSLTFMLPAYCTPDGVTVVITPLVSLQDDMAVRCQRLGIDAYIWKSREVQRAASLVFVTPESAVSKGFRTFVERMHGQQKLDRIVVDECHTVLGYSKTFRPQMGQLGATLQDFGVVSLSSDSARFDFDLKTIPRSYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGB2</accession>
    <name>X0BGB2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14405</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658429">
        <property type="protein sequence ID" value="EXK81160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGB2"/>
    <dbReference type="eggNOG" id="ENOG502RM4B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035914_0_0_1"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF116">
        <property type="entry name" value="TYROSINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938490" description="Tyrosinase copper-binding domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="3">
        <location>
            <begin position="111"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="337" mass="37032" checksum="C5DD5B1799F65EB5" modified="2014-05-14" version="1">MRCNPSFCAILLGLAATAQGSSDLASNLKREATVTSSFNPKNATLAEFNAHAREVALSRIGNSTVCNKDNVRVRKLFENLTSNERISYTDALKCLMDLPAKTPSDLAPGAKSRYDDWVVTHINQTLTIHLNANFLGWHRWYIWEMERALRSDCGYKGPFPYWDWTKTEKETFEKSEVFDGSATSLSGNGAPLNYTDSDVIVINSQYPNMEVVFPHGTGGGCVTNGPFANITVNLGPVGLALVGNKTDTSGAGYKYNPRCLKRDLTDEILHRYVNETSVLTLLRDSSDIWWFQTIMSGAWGSRDIGIHPGAHNSLGGDPGRDFWVSPGEPASVCPIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHA2</accession>
    <name>X0BHA2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_17104</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979365">
        <property type="protein sequence ID" value="EXK78208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHA2"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_17_1"/>
    <dbReference type="OrthoDB" id="408177at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845:SF6">
        <property type="entry name" value="BETA-ALANINE-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="529"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK78208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1015" mass="112250" checksum="B2633D267EEC18E0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHV3</accession>
    <name>X0BHV3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658423">
        <property type="protein sequence ID" value="EXK81710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHV3"/>
    <dbReference type="HOGENOM" id="CLU_128851_0_0_1"/>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040:SF1">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="134" mass="16067" checksum="7348747FCEBE9896" modified="2014-05-14" version="1">MELHRWIGTKQAVKIRMADNIFSRRPLNAEAKEYCINDVLHLPALQDTYTKRINRQWMKKAMHESARRVVEACSPEYKPQSKNKRLGPWGSGSGIRTLTMDEWLEKYDEDRMDRLDKEMFDNDDYDDSRRVWEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIP0</accession>
    <name>X0BIP0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIP0"/>
    <dbReference type="eggNOG" id="ENOG502SUM9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5081713at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="625" mass="71606" checksum="8C5513135102FC1B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJI6</accession>
    <name>X0BJI6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658486">
        <property type="protein sequence ID" value="EXK79038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJI6"/>
    <dbReference type="HOGENOM" id="CLU_024079_3_0_1"/>
    <dbReference type="OrthoDB" id="188042at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009291">
        <property type="entry name" value="Vps62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48174">
        <property type="entry name" value="DUF946 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48174:SF5">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06101">
        <property type="entry name" value="Vps62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935764" description="Vacuolar protein sorting-associated protein 62" evidence="2">
        <location>
            <begin position="29"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="50351" checksum="963C0926B82638E7" modified="2014-05-14" version="1">MALMCFDKPATWDLIFPLLVIQVVLVLAKPTVQHDHVVSILAKTNRTVPEYATRFAPLVWLHSEDPFRPSDIFEHIRHTTPSVNQKPISDLPKLNMDNLALLNDVSDQEVALSSNDDITTMPHWLFGSTPDETGRISNATACAVILVERDARNVDVFYFYFYSFDRGANLTQVLDPLGSLVDDTGGMHYGNHVGDWEHNMIRFRDENPVGIYYSQHSDGSAYDWGDGALSMTDGRPLVYSAYGSHANYESEGDHVHDYILVDYCDAGVLWDPIQSAYFYHMDATTSKLSRLFLPDTPMPLESNLTSFFYYLGIWGDAQYPDDHPSQITVPVFGLKRFVSGPQGPIYKSLVRKTLFPDVGEPKPFILFFIRILMAVYPCCLRGWRVWVSLGVFSVSVASLALGIRYMIRRHRTKGYDKLGTDIPLHDLESIETYARRREEEVGSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK26</accession>
    <name>X0BK26_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_13417</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK26"/>
    <dbReference type="ESTHER" id="fusof-f9fd90">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_6_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007366469" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="78"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK82171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="600" mass="65007" checksum="F8ECC087442C6DBD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKZ4</accession>
    <name>X0BKZ4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKZ4"/>
    <dbReference type="eggNOG" id="ENOG502RIRH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1115792_0_0_1"/>
    <dbReference type="OrthoDB" id="5076294at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="249" mass="27568" checksum="3C0C4E0EA2F080BF" modified="2014-05-14" version="1">MASLVPIDPKGIEAHYHGLGRKLVLKAKGTIPGYFLTPFFEQDIWTGGLRFSVKAYSGGFAKVPKDKEVKFEFELPILLPIPHFNNKSVLVETAFGTSDIKIVYLEWPEDPEDNAVAVQSVEGDAGASGSETKEGKNTVILPPIPYVLTDKGLLLLSALIPKELSSGVKIDFNPEYVKLVDTKFENGFIKWDIAWNKIPTGASDPQTVHVITTINHDIKLPVIPPFPSVTIIIQPYIVSRMWMVPDKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMB8</accession>
    <name>X0BMB8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979344">
        <property type="protein sequence ID" value="EXK79619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMB8"/>
    <dbReference type="eggNOG" id="ENOG502RSHP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3341310at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050855">
        <property type="entry name" value="NDM-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42951:SF4">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE MBLAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42951">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="344" mass="38302" checksum="84380E43F6287BE4" modified="2014-05-14" version="1">MCYKLGPPDPASVDKAPKDTYFTCRKLTKNLFYITEDDKWGENPFIYVRLYASTVVLIDTGCGGPHNSSDADFTFLRHFIEEYSVADNDSQPLNPGGAKNYTVICTHCHYDHIGGIMHFTESSTTSVVASSYDKDFIAGPDRLPTSSLCRFVGMNTPKYSVTVWAEDGQSITDSAGNDLGLVLYHAPGHTPDQLAIWDAQERFLFVGDTVYEHAPILFPIEGNIKNYVATIKRLQGLVKGWNSTESQSMYRNKPRQFCVAKILGRVLMACGHLTCNADAGELLEEVRACLQQSLVGTIQPKPCELERGEDLESYTSADKRVSFQGPRSYFIKARADQDLMSELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNR4</accession>
    <name>X0BNR4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658452">
        <property type="protein sequence ID" value="EXK80104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNR4"/>
    <dbReference type="HOGENOM" id="CLU_1938270_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="130" mass="14823" checksum="8EB74231028DC07D" modified="2014-05-14" version="1">MATINRVLDCFTSKDEKLARLLCQLVSEVIARGRASSRQETQKMLDDLIDYGVEWLLDQLSASLAIIAGMEPQPLPSAPRHIRRLIEKTRSTISTMGKAVLQIVDENRASKEYSYSSVLRYMNRYAQFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPH7</accession>
    <name>X0BPH7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658446">
        <property type="protein sequence ID" value="EXK80379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPH7"/>
    <dbReference type="eggNOG" id="ENOG502QV7T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052304_0_0_1"/>
    <dbReference type="OrthoDB" id="408743at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF2">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="10"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="150"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="435" mass="48424" checksum="3624ACD10E21C509" modified="2014-05-14" version="1">MAETQATRKRYAVVGTGGRSSFFYSAIATEYSKTSCIVALCDTNQTRMNYANSKLKSLGHGEVPTYLASNFDQMIKESKPDEVIITTMDRTHNIYIVRALELGCNVITEKPMTIDAPRCKEIFSAVERTGQKVRVTFNYRYAPHNTKVFELLRSGAIGKVTSVHFEWMLNTSHGADYFRRWHRDKRNSGGLLVHKSTHHFDLVNFWLQTRPQTVFATGDLAFYGRENAEKRGETKFYTRAHGSEVAKADPFALHLDQNPQLKAMYLDAEHEDAYYRDQSVFGDGISIEDTMNVLVKYRNGASLSYSLTAYAPWEGFRVSFNGTGGRLEVEVVENSYVNSGGDQAHEGSLESRKILLRPLFEKPREIKVEDGVGAHGGGDTVLLNDLFGTPVSDEYMRAASHIDGAASILTGIAANRSIATGQAVNVDDILLVPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPJ4</accession>
    <name>X0BPJ4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alkaline phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11809</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPJ4"/>
    <dbReference type="HOGENOM" id="CLU_015982_0_0_1"/>
    <dbReference type="OrthoDB" id="9992270at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032093">
        <property type="entry name" value="PhoD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052900">
        <property type="entry name" value="Phospholipid_Metab_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606:SF8">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16655">
        <property type="entry name" value="PhoD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936586" evidence="1">
        <location>
            <begin position="22"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipase D N-terminal" evidence="3">
        <location>
            <begin position="67"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="2">
        <location>
            <begin position="199"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="635" mass="71559" checksum="4AD281BFFEB4D361" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR82</accession>
    <name>X0BR82_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Allantoin catabolism protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14519</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK80994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR82"/>
    <dbReference type="eggNOG" id="ENOG502QS1M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056083_0_0_1"/>
    <dbReference type="OrthoDB" id="4965688at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071522">
        <property type="term" value="F:ureidoglycine aminohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02212">
        <property type="entry name" value="cupin_UGlyAH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02211">
        <property type="entry name" value="cupin_UGlyAH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017627">
        <property type="entry name" value="UGHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044697">
        <property type="entry name" value="UGlyAH_cupin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008579">
        <property type="entry name" value="UGlyAH_Cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044704">
        <property type="entry name" value="UGlyAH_cupin_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040771">
        <property type="entry name" value="AAH_UGLYAH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008373">
        <property type="entry name" value="PRK11171.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008376">
        <property type="entry name" value="PRK11171.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03214">
        <property type="entry name" value="ura-cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34571">
        <property type="entry name" value="(S)-UREIDOGLYCINE AMINOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34571:SF1">
        <property type="entry name" value="(S)-UREIDOGLYCINE AMINOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05899">
        <property type="entry name" value="Cupin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="(S)-ureidoglycine aminohydrolase cupin" evidence="1">
        <location>
            <begin position="69"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-2" evidence="2">
        <location>
            <begin position="200"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="279" mass="31076" checksum="67D777B359A87EBC" modified="2014-05-14" version="1">MGGNDNTVGAYYAPKGGLPPQTQLLTDRAMFTESYAVIPKGCFSDIVTSFLPFWEQTRLWVIARPLSGFAETFSQYIMEVQPGGGSDRAEMDDTAEGVLFVVEGEITVTLAGEAHTLSSGGYAFLPPKSGWTLRNNSSEAARFHWVRKAYESVPGLDAPEAFFANEKDIEPREMPDTNGAWATTRFVDPTDVRHDMHVNIVTFQPGGIIPFAETHVMEHGLYVLEGKAVYRLNQDWVEVEAGDFMWLRAFCPQACYAGGPGKFRYLLYKDVNRHAKLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR91</accession>
    <name>X0BR91_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR91"/>
    <dbReference type="HOGENOM" id="CLU_3335607_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="38" mass="4180" checksum="1430DF31F9187E87" modified="2014-05-14" version="1">MECKKTKPDSPSLYTIGWIAALAIEQAATRALLDEEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS69</accession>
    <name>X0BS69_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11227</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS69"/>
    <dbReference type="HOGENOM" id="CLU_038300_0_0_1"/>
    <dbReference type="OrthoDB" id="512662at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF44">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="503" mass="55938" checksum="CD0F7C5B1672042D" modified="2014-05-14" version="1">MSSFCHKLRCNHMIINPLRVITPSCHAFGLTSMSSRSRRGCWTCKRRHKKCDEKRPVCDRCVQAGMTCEGYKTRLTWGSSDTASSAGGGIVLKPIRPPRQKSKSLRNRRVSPAVETVGDPLVDLPDFSSMQSPDELDLLCLQFESLSEGLPDEEVSQRLMNTFTTIGYQTLTGRAGHDTMFKSDILPLCEDSICLKHACLAYQASLDVDTSHLTPLYMQSALSNYLNDLENPSMLCQDVTLATGVLLCSVSINSLYIWSPLLKGLHGVLQARELLNDPQRPPVANHLLEAVGLLDIPFFTLNRITPSLEIWKSYVQPHKHSGIEQVSGIPYSLMNLLANMDSTTIEQDLLQWPGELGDEFAQIHLWEAFRLAGILHSRCLADHPQDQTNPPTAKVSTEILRMKVFASIQAIIGIGTFNFRLSLARAILYPLFIAGILAENAQEQQLTRVAFQYIMQKGQEGTEQIILDIVAKVWKNGKGGNEASKLMIATEATGELNAEIHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSE9</accession>
    <name>X0BSE9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSE9"/>
    <dbReference type="HOGENOM" id="CLU_411656_0_0_1"/>
    <dbReference type="OrthoDB" id="1262810at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="800" mass="91039" checksum="5DD12F48DEEDB075" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTC0</accession>
    <name>X0BTC0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ergosterol biosynthetic protein 28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658423">
        <property type="protein sequence ID" value="EXK81719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTC0"/>
    <dbReference type="HOGENOM" id="CLU_1992168_0_0_1"/>
    <dbReference type="OrthoDB" id="10042947at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13556" checksum="BC1553FDB3E5C49A" modified="2014-05-14" version="1">MPSITAITIFIFGLSAFNHGVSNLISPRKGLAAKQLPESALPALNGFSVAIIGIGIYYMLAAYQENRGFFALTLARFISARIFWVQGPAWRVIATWEAFSAGLTAVALAYEGYYGRYAGWPDGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUA0</accession>
    <name>X0BUA0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_10567</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUA0"/>
    <dbReference type="eggNOG" id="KOG0569">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_5_1"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="427"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="16"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="250"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK85481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="503" mass="53705" checksum="9BE3A29C7BDB0545" modified="2014-05-14" version="1">MAGIRLRDVSGYLILLIAITTLGSLQFGFHLAELNAPQDVITCRKKSISALDKIKGLVYKPKDDDAVSGFMPHCIPMDEASFATISSIFMLGGLLGALASGPFSSKRGRLPAMRITGLLYLFGAAVETVAGSVFVMVLGRLFAGIGAGASTVVVPLYISEIAPPKERGLFGFMTQISINFGILVVQTMGFFLSYGTAWRWILATGVFIATAQTLGLFVVPESPSWLAAQGNAPKAKRTLQRIRGNGYDIHEETETWDSDDRDASEEDGLLQADSASESPSKTRTEHLGFFEVLRDPDTRPAIVAVVGIMFAQQLCGVNSIIMYSVSLLADLLPVSSSLLTILVSVVNLFTTIACAPLPDRLGRKTCLLASIIGQGTSALILAISIIFGIKILSAIAVVAFVGFFAVGLGPVPFLISSELVGQEAVGATQSWCLAANYAATFLVAQFFPIVNSALNDLLGGHGWVYFIFAGLAAGSAIFVFWNVPETKGKKDVDEVWGRTRRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUH1</accession>
    <name>X0BUH1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUH1"/>
    <dbReference type="eggNOG" id="KOG4372">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007367_0_0_1"/>
    <dbReference type="OrthoDB" id="5368485at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016445">
        <property type="entry name" value="Rog1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF62">
        <property type="entry name" value="LIPASE ROG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005412">
        <property type="entry name" value="UCP005412_abhydr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="268"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="327"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="437"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="219"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="310"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="628"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="695"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="799"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="938"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="628"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="735"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="810"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="824"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="845"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="865"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="939"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="978"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="993"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1010"/>
            <end position="1029"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1089" mass="119642" checksum="5B044F47BDA465AC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVN4</accession>
    <name>X0BVN4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVN4"/>
    <dbReference type="eggNOG" id="KOG4754">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039184_3_0_1"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="18388" checksum="4EA1F5848AA6A415" modified="2014-05-14" version="1">MTRTIQTMYIVFRYLLHSTKTPVQVWPDLREAHDATCNKGISRKELADKFPNLDFSACPEKWDFPTHTPDDATVRAERVRRRLKDVARTGGYKNIMLVTHRGIAAFLVQGDRFSVCEHRSYRFATNEEVDKARHGVNVDTGLEQDFGPTVLIPAEKPKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW50</accession>
    <name>X0BW50_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sequence orphan</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658405">
        <property type="protein sequence ID" value="EXK83148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW50"/>
    <dbReference type="eggNOG" id="ENOG502QWAD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054095_2_0_1"/>
    <dbReference type="OrthoDB" id="275936at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038781">
        <property type="entry name" value="C365.16-ike"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37845">
        <property type="entry name" value="SEQUENCE ORPHAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37845:SF1">
        <property type="entry name" value="SEQUENCE ORPHAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="29595" checksum="854C10B0CF4947DA" modified="2014-05-14" version="1">MTDVMSIREQQRCTLQYFAVDLAAAAFASALVTPWVTAIDKLVFNKATSNTSIKSSMRKWASKPKATFASLFIPFLVYFGTYATANMFDSFNAVQYDCDPSIVCSSPAKFAATTTVSSGLSIFKDAYFSRMSCGMSTPLLSYALFTLRDAVTIYASFNLPTMIAPKLAEFPFASITPFANIFQSDDARLKMAQLFMPAASQIVSTPIHLLGLDVHARQVRMTIKDRISVIRRYTGFATPLRMIRVLPSFGIGSVANTGFRRSMMTRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYZ3</accession>
    <name>X0BYZ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19487</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979849">
        <property type="protein sequence ID" value="EXK75747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYZ3"/>
    <dbReference type="HOGENOM" id="CLU_3384829_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="33" mass="3827" checksum="B7C358BCC1580611" modified="2014-05-14" version="1">MQLLQQSGCNCTLMQNYLVYESDRYIQALQGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZA4</accession>
    <name>X0BZA4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Branched-chain-amino-acid aminotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_12006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZA4"/>
    <dbReference type="eggNOG" id="KOG0975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020844_4_1_1"/>
    <dbReference type="OrthoDB" id="25921at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000002">
        <property type="entry name" value="D-alanine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050571">
        <property type="entry name" value="Class-IV_PLP-Dep_Aminotrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42743">
        <property type="entry name" value="AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42743:SF11">
        <property type="entry name" value="AMINODEOXYCHORISMATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK83849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="36072" checksum="B7877C754A753AE1" modified="2014-05-14" version="1">MATMDEVFAGYAKRQATLEASTNILSQGIAWVEGELVPLQSARIPLLDQGFMHSDLTYDVPSVWDGRFFRLDDHLDRLEASCKKMRLRFPIPREEIKKILVEMVAKSEIKDAFVELIVTRGLKGVRGAKPEELLNNNLYMFVQPYVWVMDPEDQYHGGRAIVARTVRRVPPGSIDPTIKNLQWGDLVRGLFEANDRGATYPFLTDGDANLTEGSGFNVVIIKNGVLYTPDRGVLQGITRKSVIDAARSCGYEIRIEHVPVEAAYQADEILMCTTAGGIMPITTLDDKPVNDGKVGPITKAIWDRYWAMHWEDEFSFKIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0C0</accession>
    <name>X0C0C0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM170 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0C0"/>
    <dbReference type="eggNOG" id="ENOG502S0YM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071343_1_0_1"/>
    <dbReference type="OrthoDB" id="2131401at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019334">
        <property type="entry name" value="TMEM170A/B/YPR153W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22779">
        <property type="entry name" value="SD17342P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22779:SF6">
        <property type="entry name" value="SD17342P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10190">
        <property type="entry name" value="Tmemb_170"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK84184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="16010" checksum="704B20A20B0F4A81" modified="2014-05-14" version="1">MALPNTPPPDYQTPRFPSLNVQTLSDTTTDKQFTLYYVLDVWRFTLLWTLIIYACFHMGAVLIAMFTHGWKKSSWRYLWAVPVIYLVIAGLEAVMAGSIVGLVLGAVYSAGYYEMNTWIPCTWGFINVLVLIISSFSIQGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0J7</accession>
    <name>X0C0J7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979537">
        <property type="protein sequence ID" value="EXK76327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0J7"/>
    <dbReference type="HOGENOM" id="CLU_174957_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="108" mass="11940" checksum="8669942684BAF97A" modified="2014-05-14" version="1">MITTQSGPSSVKSQHCFGLDSVGISTQLRVAIQTTDPEIRDFLVEKQEEWAADSRTTTVETKKWFTYAVADFPRGLADFHGNKLDSGSVVNDEIEIQTGLKPVAERPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0W5</accession>
    <name>X0C0W5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0W5"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_1_1"/>
    <dbReference type="OrthoDB" id="433474at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="109"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="349" mass="38172" checksum="BD679CA6ED729697" modified="2014-05-14" version="1">MTYPFPYSQAAKLDSRIKIPRPTYDPDLAPLLDSASFPEEFDLNLMRGVASGEQECSHGSFIFNAETVLRDNPHLSHTEHSIPGPDNNIITLSVFEPNEPSKAPRPVLYHIHGGGMVSGDRFTAVTPVIDLLKGIDCVVVSVEHRLAPETRAPGPADDCYAGLVWVSENASSLGIDPAAIVVFGVSGGGALAAATCLMARDRKRPAIPIKAQMLYSPLLDDRCESLADQQFEYGNPASTAWLRAIWDLILGDARGSEHVTPYQAPARETDLSNLPAAYIDAGECEVFRDVAVAYATKMWRGGSTCELHIWPGAWHGFDMMDDPNMPLIHMANMAKANWLQRVMRSVKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1Z3</accession>
    <name>X0C1Z3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1Z3"/>
    <dbReference type="eggNOG" id="ENOG502RJ4A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2210199_0_0_1"/>
    <dbReference type="OrthoDB" id="5088640at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="107" mass="11579" checksum="BA5D27DDF0290072" modified="2014-05-14" version="1">MSSSIQTLSRGVRTAPRALRGLTQVRRLSTTEPSRNLSNTRDSAVHDPIMDKFWGNRVNVSETSAIVTETPSISATTTSRDPPLGTNVFEPSSAPRWSGISIPAGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2I0</accession>
    <name>X0C2I0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08398</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2I0"/>
    <dbReference type="eggNOG" id="ENOG502QV54">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000023">
        <property type="entry name" value="Exo-beta-1,3-glucanase Exg0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039279">
        <property type="entry name" value="QRT3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928:SF2">
        <property type="entry name" value="PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928">
        <property type="entry name" value="POLYGALACTURONASE QRT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="780"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="877" mass="94590" checksum="97D1A9E15186BCC6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3H6</accession>
    <name>X0C3H6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3H6"/>
    <dbReference type="eggNOG" id="ENOG502S06P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071891_1_0_1"/>
    <dbReference type="OrthoDB" id="5220781at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="326" mass="35697" checksum="A5708C0DDE442990" modified="2014-05-14" version="1">MASHLRSFAPSLDEIKIDQITESRIFNVVSMLPNSLPGPIRFLRRSISFHTLRPGVTISGPQTKPRPLSEADVSATMAQPLQTDMIKHSGGFVESQDLNPQPMSRVLYSEAPEDEPVMRAASGVHWKFARQGTNLVNISIDGGKAAVAEEDIAFERKAFVDGVTYLLKALPQELDEGELRRIQCALPEQVNQSDMALARAEPDSNHIHPSQSRSIIHRGVQMTVVNLIFFLSFLMPYLLLLVRCAARLERKYKISEKVVGHGVDLVNTIGKQSALLTEAIGQMNDGKVAQALLEVFVWTVDGVTQGISDGLGEGLSMVGSKPKMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3K3</accession>
    <name>X0C3K3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prefoldin subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK88995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3K3"/>
    <dbReference type="HOGENOM" id="CLU_122140_0_1_1"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23164">
        <property type="entry name" value="Prefoldin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="118" mass="13478" checksum="C821CD8838B3B520" modified="2014-05-14" version="1">MSIPNEALQKLVREIESQALVAQQQIGLARTQMTSKQREQRLVKLTLSEMASLPQDAVVYEGVGKMFVSLPVDSLRQKLESQTQTLEGEVDKLSQRLLYLETTHKNSREHIEQMLRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3P2</accession>
    <name>X0C3P2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Golgi apparatus membrane protein tvp15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_10223</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3P2"/>
    <dbReference type="eggNOG" id="ENOG502S5TF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120579_0_0_1"/>
    <dbReference type="OrthoDB" id="423534at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013714">
        <property type="entry name" value="Golgi_TVP15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28128">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28128:SF1">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08507">
        <property type="entry name" value="COPI_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK85783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="14057" checksum="0E021E0399C790AF" modified="2014-05-14" version="1">MELSDIFRIVNLAVGVITVLGGIASIFHLGLQPIVVGAYMIVFGLVIALLEFQIPPQVSRHASFMFSFVGRGVFYVFIGCLLLGNFILSKIAGSIIGIVGLAYIALEFVPSIEPPSNMREAEDAGWGAEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3S4</accession>
    <name>X0C3S4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08071</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3S4"/>
    <dbReference type="eggNOG" id="ENOG502QYYF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070374_0_1_1"/>
    <dbReference type="OrthoDB" id="4993254at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936159" description="Mid2 domain-containing protein" evidence="7">
        <location>
            <begin position="21"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="133"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="133"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK88781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="29642" checksum="6EB8A56206848927" modified="2014-05-14" version="1">MLGLLPACLAVIAFAGHVQCSSDFITPELSSAPWSENQVYEVDDEFEIKWTTDHKGCNLFLWQDYPKLAVEWYSKLLENTTETSHVWNASSSGFSQESEDTVFHFALYSSDKDIPLANSGSFNISGTNSSKLKATSVSNSTPASTASQASETSMVSSETTNHSVTKSENDPGLSTAALVGISVGVTVAGLLISGGIGLCLWRRFKRKRTTERVDSIEKSDFTKAELGNAQILQIGSSELDSTRDAAELWDTQKPGELGDENKIRTIYGLHEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4B3</accession>
    <name>X0C4B3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH OST-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658590">
        <property type="protein sequence ID" value="EXK77602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4B3"/>
    <dbReference type="HOGENOM" id="CLU_034061_0_2_1"/>
    <dbReference type="OrthoDB" id="5205629at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10146">
        <property type="entry name" value="LabA_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11297">
        <property type="entry name" value="PIN_LabA-like_N_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="entry name" value="LOTUS domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35811:SF1">
        <property type="entry name" value="HTH OST-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35811">
        <property type="entry name" value="SLR1870 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="211"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="298" mass="32670" checksum="E9CB87CE432E2F88" modified="2014-05-14" version="1">MAAVARSVKLAVLIDADNTSPNAVCFILAEIAKFGTASVKRAYGDWTSPGLNRWKTPLLENSIQPMQQFAYTTGKNSTDSAMIIDAMDLLYSKSFDGFCIVSSDSDFTRLASRIRESGLVVYGCGERKTPKAFVTACDRFIYVENLMPTTEAPRPVGSDGPSSAAGLSASSSSLPVHTLLAKRKRVESRLEKEASIDAQAVGSLTIETREVDEEVIDLLWEAVEIAADEEGWAVLSKVGSLITKWHPDFDSRTYGFRKLKELMASTSLFEIIHRSPGLGKPELAYARCSVEQWEARLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4R7</accession>
    <name>X0C4R7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">endo-polygalacturonase</fullName>
            <ecNumber evidence="3">3.2.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_17557</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(1,4-alpha-D-galacturonosyl)n+m + H2O = (1,4-alpha-D-galacturonosyl)n + (1,4-alpha-D-galacturonosyl)m.</text>
            <dbReference type="EC" id="3.2.1.15"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.15" evidence="3"/>
    <dbReference type="EMBL" id="JH658578">
        <property type="protein sequence ID" value="EXK77742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4R7"/>
    <dbReference type="HOGENOM" id="CLU_098123_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050434">
        <property type="entry name" value="Glycosyl_hydrlase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884:SF1">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="active site" evidence="12">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK77742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="200" mass="20413" checksum="776CBF081EBB8EDB" modified="2014-05-14" version="1">MDPFPPIPHRSYYVVDLNPVGGSTGVTITGAKVYNQDDCVAVNSGTDITFSGGLCSGGHGLSIGSVGNRDNNVVDNVKFLNSQVTKSDNGIRVKTVKGASGKVAGVTYSGITLSNIAKYGIIVEQNYDGGDLKGEPTSSLPIAGLTMKDITGTGAVSSSGYNIAIVCGSSGCSNWTWSNVKVTGGKTYGSCENVPSVASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C648</accession>
    <name>X0C648_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ras-like protein Rab-11B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_09961</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C648"/>
    <dbReference type="eggNOG" id="KOG0087">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_23_0_1"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000085">
        <property type="entry name" value="Putative ras-related protein rab-11a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK86279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="212" mass="23263" checksum="B1F31D52841036E5" modified="2014-05-14" version="1">MANDEYDFLFKVVLIGDSGVGKSNLLSRFTRNEFNLDSKSTIGVEFATRSIQVDSKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDISKHQTYENVTRWLKELRDHADANIVIMLVGNKSDLRHLRAVPTEEAKSFASENHLSFIETSALDASNVELAFQNILTEIYRIVSSKALDSGDSAQATIGAGTNISLSKPADDDAAKGGKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C688</accession>
    <name>X0C688_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C688"/>
    <dbReference type="eggNOG" id="ENOG502S7B4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056574_1_0_1"/>
    <dbReference type="OrthoDB" id="10255128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01427">
        <property type="entry name" value="HAD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050849">
        <property type="entry name" value="HAD-like_hydrolase_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181:SF1">
        <property type="entry name" value="COLD TOLERANCE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181">
        <property type="entry name" value="UPF0655 PROTEIN YCR015C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="268" mass="29920" checksum="FAAC18CE81803B76" modified="2014-05-14" version="1">MHLVFDFDGTITQEDSIGELARSALEIQRNKYGHDLQTSWDQVVQSYVADYRHYKDNHPSPEVTRTSVDHEIEFLSGMKDVEETSLGRIADSRIFAGLDAETLSQAGADAVKAGRIKIRDGFTDLITLARQRGWNVSVISVNWSRAFLRGALLPHKIEVIANEPASDGTIKGPEFFEGRMTNVCEKKKALKHIINEKDGKVVYFGDSTTDMQCLLTGGVVISDNEESSLLKTLRRVSIEVPHVGEKRNGKISWARNFREVLDSGVLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6Y2</accession>
    <name>X0C6Y2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exoribonuclease phosphorolytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_07375</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6Y2"/>
    <dbReference type="eggNOG" id="KOG1069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063514_2_2_1"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11372">
        <property type="entry name" value="RNase_PH_RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="6">
        <location>
            <begin position="9"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK89896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="250" mass="26937" checksum="60B8E61BA13762AC" modified="2014-05-14" version="1">MAPLAEPAAELSHLAKADGSATFSYGGYAVIAAVNGPVEAQRRDENAFEALVDVIVRPAAGVGGTRERQLESIMQAAIRQLIPVRDYPRCVIQITLQVAETPENAYVNAKLVQAQLNLPIIPALLHSAILGLLSAAIPLKSIGAATLLAIPEEEGKGIIVDPSAVDIDHAKSVHVLGFTSHDELLLSESEGAFTPAEWTNVLQLGQRICCEHQQPGFDTTMSGDDMESRSMRQFIRSVMEAKVAEDLYWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8Q4</accession>
    <name>X0C8Q4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sphingosine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8Q4"/>
    <dbReference type="OrthoDB" id="3853857at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055916">
        <property type="entry name" value="DUF7493"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24321">
        <property type="entry name" value="DUF7493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="149"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="534" mass="58866" checksum="1FE079E5E1D46A0F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8Y1</accession>
    <name>X0C8Y1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_223993_0_0_1"/>
    <dbReference type="OrthoDB" id="4941399at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="2274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2292"/>
            <end position="3305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3336"/>
            <end position="3538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3553"/>
            <end position="3573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3671"/>
            <end position="4121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="918"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1051"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1064"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1136"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1207"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1258"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1346"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1361"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1382"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1409"/>
            <end position="1418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1429"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1452"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1537"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1572"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1589"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1639"/>
            <end position="1663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1718"/>
            <end position="1736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1772"/>
            <end position="1781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1810"/>
            <end position="1820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1864"/>
            <end position="1888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1964"/>
            <end position="1973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2023"/>
            <end position="2044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2058"/>
            <end position="2099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2167"/>
            <end position="2183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2221"/>
            <end position="2248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2261"/>
            <end position="2273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2314"/>
            <end position="2324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2334"/>
            <end position="2353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2476"/>
            <end position="2502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2510"/>
            <end position="2522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2601"/>
            <end position="2612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2728"/>
            <end position="2737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2744"/>
            <end position="2753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2791"/>
            <end position="2812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2869"/>
            <end position="2889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2897"/>
            <end position="2914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2966"/>
            <end position="2977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="3031"/>
            <end position="3053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="3076"/>
            <end position="3085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3336"/>
            <end position="3361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3379"/>
            <end position="3390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3414"/>
            <end position="3424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3671"/>
            <end position="3692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="3693"/>
            <end position="3705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3711"/>
            <end position="3805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="3819"/>
            <end position="3833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3854"/>
            <end position="3864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3870"/>
            <end position="3918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="3936"/>
            <end position="3945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3946"/>
            <end position="3962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3989"/>
            <end position="4013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="4024"/>
            <end position="4107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="4121" mass="443383" checksum="D0E51EE1B99A5B0E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9X2</accession>
    <name>X0C9X2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinetochore protein mis13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658469">
        <property type="protein sequence ID" value="EXK79492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9X2"/>
    <dbReference type="eggNOG" id="ENOG502S2VJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021697_1_0_1"/>
    <dbReference type="OrthoDB" id="3364649at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013218">
        <property type="entry name" value="Dsn1/Mis13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778:SF2">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08202">
        <property type="entry name" value="MIS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="519" mass="57304" checksum="5A4D2D7BF4FD1332" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>X0CA06</accession>
    <name>X0CA06_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Helicase-like transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_15847</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979346">
        <property type="protein sequence ID" value="EXK79527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CA06"/>
    <dbReference type="eggNOG" id="KOG1001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_2_5_1"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014905">
        <property type="entry name" value="HIRAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF11">
        <property type="entry name" value="FAMILY HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G06590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08797">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00910">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="331"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="652"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="724"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK79527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="890" mass="99779" checksum="76399E685B4A90F3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CA21</accession>
    <name>X0CA21_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication factor Cdt1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_06698</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cdt1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CA21"/>
    <dbReference type="eggNOG" id="ENOG502S8WG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031309_1_1_1"/>
    <dbReference type="OrthoDB" id="341730at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1420">
        <property type="entry name" value="DNA replication factor Cdt1, C-terminal WH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032054">
        <property type="entry name" value="Cdt1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038090">
        <property type="entry name" value="Cdt1_C_WH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16679">
        <property type="entry name" value="CDT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26121">
        <property type="entry name" value="HTH_CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Cdt1 C-terminal" evidence="4">
        <location>
            <begin position="352"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK91260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="479" mass="52888" checksum="2CFB9861D9C424D3" modified="2014-05-14" version="1">MPRPARRSQAAPSASHSITNFTRVSKTCTPNDNAKKIVGQTSSSVTTRKRKAATDGEDVHPRTKARTASFAPSSDDELATPIKPESRNQELVANLVEKNIPFAKGKRTAKTTPSRARTAHKPIGTTPLSESKRQGKTVQTKLDNVFKTLRKHTVDKDALPLHLAELIDIHRSFVKTIMIQFAHNGNNSPIDIRTLAPHISQSWGKRQVTIEDIRRCIAIQTSTKTNTHSPFMIADYGRGKICVERSSIDMAPIHEERLLKQFEINLRALGTERSADEMDIDLPLDNLSLNELPQVDIKNMDNRTTANPILNKGQRALSELKSGIVTKQHEKAAKQNAASNSPLLNPDGTKMSLLDRLRLKQLAKANEPLPPSGPELQRRAALNRVGDVAATISMLSLSNPMSLPRQAFTMAVILEKLKDSLRVPVSKEEGAACVRLIASEVAPEWLRVVTIGGRENVVVQRSSQPVDRVLQNRVQKLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB79</accession>
    <name>X0CB79_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sterol O-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_06752</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Sterol O-acyltransferase that catalyzes the formation of stery esters.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB79"/>
    <dbReference type="eggNOG" id="KOG0380">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018190_2_1_1"/>
    <dbReference type="OrthoDB" id="10039049at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034737">
        <property type="term" value="F:ergosterol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008204">
        <property type="term" value="P:ergosterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF23">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="581"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK91386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="657" mass="75327" checksum="0D429E1F4B16B4AD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDA4</accession>
    <name>X0CDA4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14843</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658439">
        <property type="protein sequence ID" value="EXK80637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDA4"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF127">
        <property type="entry name" value="3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK80637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="26702" checksum="77BB9260AE5082E9" modified="2014-05-14" version="1">MSQETKTVLVTGSGGGLGRAIVDAFLANGFNAIVSDVNQARLSEAEVLYKETHPGRVLVNEANVTDEASVENLIAATVEKFGRLDVVVNNAGVMDHFDPSGTCDKGMWDKVIDVNLTGPFLLTKHAVKVMEKQGTGLIINIGSNASVRGISAGIAYTASKHGVIALTKNTAGFYGPRGIYSAALILGGMDTNISDAFTDGINMEGMQLMKATMPGMVSVPTQQVARYIVFLSEEGISRGANGSCITFNGNWPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDB3</accession>
    <name>X0CDB3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14853</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658439">
        <property type="protein sequence ID" value="EXK80647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDB3"/>
    <dbReference type="HOGENOM" id="CLU_027506_3_1_1"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02183">
        <property type="entry name" value="GH16_fungal_CRH1_transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF68">
        <property type="entry name" value="GLYCOSIDASE CRH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936950" description="GH16 domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="31"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK80647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="391" mass="42040" checksum="E1CE26ACCA0F44F1" modified="2014-05-14" version="1">MLNKILSSGAVGFAAWIHLVSAQKFTDCNPLKEDCPPNPAFRKGVTMCNFARGECGAFRENPGSMIKYDKKGAKFTIMNETNAPTIATGKYIFFGRVDVEMQAAPGQGIVTAVVLQSDTLDEIDWEWLGGDATQVQSNYFSKGETTTYDRGGFHDIVEPLTTFHKYSIEWNKDAVQWIIDGKIVRTLKAAEAKGFPESPMQIKLGTWCAGGSQTEEGTVMWAGGLTDFSKAPFDAYYKSVTIVDYAGGKSPTTKGVKEYVYGGNSGGSDSIKVKYRSSSDEENNAGSKDQPKPIDNAEESDREENDTSKEDKSKPTGTTTENKAVGEEVDHSTPIIHKPNDGVIGLNFTAIPIGTPAPGNTGSDVPQSAASRGTTQGGLIAGIMFLFCLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDY8</accession>
    <name>X0CDY8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05706</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4066896at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057454">
        <property type="entry name" value="Bud3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF261">
        <property type="entry name" value="BUD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25351">
        <property type="entry name" value="PH_BUD3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="3">
        <location>
            <begin position="248"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="819"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1089"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1355"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1382"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1458"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="827"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1251"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1329"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1362"/>
            <end position="1373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK92630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1498" mass="166994" checksum="1356612F9017AF15" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE07</accession>
    <name>X0CE07_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14634</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658434">
        <property type="protein sequence ID" value="EXK80862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE07"/>
    <dbReference type="HOGENOM" id="CLU_1731560_0_0_1"/>
    <dbReference type="OrthoDB" id="4682787at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK80862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="151" mass="16687" checksum="70EEC4FCD3693409" modified="2014-05-14" version="1">MVLLPQRTIWALNMNWQKKLGMSVIFGVGLITCIAACFRLSHTVTFSQEADRMYYIGPLLFWAWAEMTAGFFILSVPCLPKFVKESRLPTGFKAFLGLSVQTNPPIGGSTDLVTFGGSGGPVRKPLSKDSVPHRDSYYEIGDDEIHLSNIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEE2</accession>
    <name>X0CEE2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK81007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEE2"/>
    <dbReference type="HOGENOM" id="CLU_2096987_0_0_1"/>
    <dbReference type="OrthoDB" id="5069609at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937128" evidence="1">
        <location>
            <begin position="20"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="129" mass="13702" checksum="86CC1B56EA9423B3" modified="2014-05-14" version="1">MQLSTVLLNALLAFSGVAALLKGEPAASAKLIDINSVGEVSEIPESEIAPAGTKTVFDEHASHNPGLNKRQVLWGLCLGNAGLPSRKVEQYKSAVRSVFDEIAQWDPRSQRSVSRGTGPVLRPVAIGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFR2</accession>
    <name>X0CFR2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_14104</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFR2"/>
    <dbReference type="HOGENOM" id="CLU_005533_5_0_1"/>
    <dbReference type="OrthoDB" id="3340390at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF17">
        <property type="entry name" value="O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="5">
        <location>
            <begin position="291"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK81467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="458" mass="50591" checksum="E96FFE5358B86C81" modified="2014-05-14" version="1">MADTTVSHTNGHTVPETEYRGTEKKLESSVSALSSSGSSDGTPDATNGNKSEEPDVSIALNAANIDAVPSLIKEINALSGDLDSDDPTARLKLMAKAKSLWQSLETPRETMLRHVWAEPSLHCALTAGTVKEVWTHVAKIDGPFKVADVAKEKNIEPALLARLVRHVSSMGYITEIDQDTYQATNFIKSMAFPFINAGYPCISGACLNALGQFHEWADINSWRDATDISNSPLQLGYKTEKTFFEHLHTNPPYGQLFHLHMGGYRQGRPSWMDAGFFPVQEKLINGFERSDDAALLVDIGGSFGHDIGEFCGKFPDAPGRLILQDLPVVIDQITALDNKIERMKYDFYTEQPIKGARAYYMHSVLHDWSDDTCLKILAQVKAAMKPGYSKLLINENVIPNTGAQWEATALDIMMLTLLASRERTQENWEKLLGEAGLKICNIWTVANGVESLIECELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGW0</accession>
    <name>X0CGW0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_07264</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGW0"/>
    <dbReference type="eggNOG" id="KOG1888">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003016_0_0_1"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043813">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043573">
        <property type="entry name" value="Fig4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738:SF5">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="5">
        <location>
            <begin position="237"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="760"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="761"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="785"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK90488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="976" mass="110538" checksum="7F16C349ABC45B70" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHE4</accession>
    <name>X0CHE4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_13668</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK82027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_35_0_1"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001465">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000054">
        <property type="entry name" value="ABC multidrug transporter atrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="591"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="694"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1118"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1147"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1189"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1227"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1254"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1377"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="85"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="779"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="730"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="744"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK82027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1412" mass="156274" checksum="8BCA8D0496DA2B57" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJS2</accession>
    <name>X0CJS2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJS2"/>
    <dbReference type="eggNOG" id="ENOG502SQDU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057752_1_1_1"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="23"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="237" mass="27069" checksum="2326219FB5D1CA6B" modified="2014-05-14" version="1">MQSPPYEEFGASLKNYFNNTTLSDATIRCEGRYFSVHSLILFCHSEYFRKQLDGPWKESSERVIDILDFNPPIVEAMTLFLYCFDYESPADSSAMMFHAKVYQIADKYGIEALKRLSATKFRASIDENWKTDDFPAAIALAYTTTPPEDRGLRDITVQVAFNNIGTLMSRDAFCETLSDNPDLAADIIRFMHGKWEEFEEYKCSSCKGVFLIGTVTIKTGDSPFIFLWYCPRCQAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJT9</accession>
    <name>X0CJT9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_06610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJT9"/>
    <dbReference type="HOGENOM" id="CLU_007426_4_0_1"/>
    <dbReference type="OrthoDB" id="4934715at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK91104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="666" mass="75939" checksum="B6D547B947F60200" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CK14</accession>
    <name>X0CK14_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12857</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CK14"/>
    <dbReference type="HOGENOM" id="CLU_3351124_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="37" mass="4466" checksum="C9A3D974CCA3F70B" modified="2014-05-14" version="1">MPPQVQCKSYSNSLSGKRSRQGWRDLWSWSVRWVRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLG1</accession>
    <name>X0CLG1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03884</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLG1"/>
    <dbReference type="eggNOG" id="ENOG502SD7F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006524_7_0_1"/>
    <dbReference type="OrthoDB" id="5226580at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF32">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="577"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="628" mass="69749" checksum="8F5CC79F03CAE7B9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLW4</accession>
    <name>X0CLW4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_04006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLW4"/>
    <dbReference type="eggNOG" id="ENOG502QW6D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011003_0_1_1"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF17">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="58"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="132"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK95435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="677" mass="76098" checksum="B59D49E27B9FC31F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLY0</accession>
    <name>X0CLY0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cysteine synthase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLY0"/>
    <dbReference type="eggNOG" id="KOG1481">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039949_1_0_1"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000058">
        <property type="entry name" value="Cysteine synthase B, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="391"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="534" mass="58756" checksum="CE4F85C7778A0113" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPE2</accession>
    <name>X0CPE2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gastric mucin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPE2"/>
    <dbReference type="eggNOG" id="ENOG502RVJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006328_0_0_1"/>
    <dbReference type="OrthoDB" id="5401106at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="845"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="899"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="916"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="981" mass="107665" checksum="2D896123307FA0F2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPM0</accession>
    <name>X0CPM0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPM0"/>
    <dbReference type="HOGENOM" id="CLU_2831246_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="66" mass="7384" checksum="1CAF0A37E7B9CDA2" modified="2014-05-14" version="1">MGDEVLHQWQGYPNGTRAPSRAPHLIGAAKKLLGKQKRLREGAIRSTSTFRPSYKTQYLSEQTSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPS3</accession>
    <name>X0CPS3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPS3"/>
    <dbReference type="HOGENOM" id="CLU_2306266_0_0_1"/>
    <dbReference type="OrthoDB" id="10422228at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="107" mass="11989" checksum="A5E0A2A35E90C839" modified="2014-05-14" version="1">MKPVAQFVSSFTDRIILSLSSSVFFVEGESKPKPEKDSGADDYSGHQACRNAHRLRPHFRHRFENQTHDVFNKEFTGCQKSRGGLSISINVSPNSSTKHSETHSHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR14</accession>
    <name>X0CR14_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR14"/>
    <dbReference type="eggNOG" id="ENOG502T3V4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079940_0_0_1"/>
    <dbReference type="OrthoDB" id="5091484at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="309" mass="35984" checksum="C8EB0FA77261FCAE" modified="2014-05-14" version="1">MSRNVSNFPLFLGAAASFALGFLAVYLLKDKGVESKKIDCFDKLSAELKFQIFEQCDSMSDVASLIAASPSVRVCFRANQDKLLRSRISYIREIFYNDELIPLTLMVARMRRRLKRRYDMYQLVGLLEHFVRGGRSKLFQRKFNHWQENLIQIQDLVNICTEIQELSPRACYNLSAAYAKPLLSKLWHHRFVETYLREEISTAMKYYGSRLMFPPRNNLSPELYVFLFTRNYVGSRLPDKHTADIVDTHVSIGRLGARSFGEMISIAGDPLKSQGISKRRKAEIQSWRDMRRKTWKEEDKKVQNGQMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRN7</accession>
    <name>X0CRN7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_02429</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 6 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRN7"/>
    <dbReference type="eggNOG" id="KOG3169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060172_0_0_1"/>
    <dbReference type="OrthoDB" id="344220at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.580">
        <property type="entry name" value="Mediator complex, subunit Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007018">
        <property type="entry name" value="Mediator_Med6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016612">
        <property type="entry name" value="Mediator_Med6_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038566">
        <property type="entry name" value="Mediator_Med6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13104">
        <property type="entry name" value="MED-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04934">
        <property type="entry name" value="Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF013286">
        <property type="entry name" value="MED6_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="177"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="240"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR013286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK97110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="317" mass="34866" checksum="53897432F0A3E30F" modified="2014-05-14" version="1">MSNPNDPPLDEIQWRSPMAIQQMGGLHNNTILFYFAESPFFERTSNNAVVYNQAMNVPSMYPVIQTREAFETHLNTMSGLEFRVVEEPAETGPGAGTGVWVIRKQTRRKSAYDDDEITVHATYFVVGENIYMAPTLSAILSARILTISSQVTNAVTTAESVRKWGPSMGNFYQLPSAKTSTKPRIHTSAAATPMPVSDEASKAPAAPTAAAQKDDEKSLERLAEESFMIHMKYGGEYIDENPITGRPGEFHLTTTGRKPPQIAKTDGPIRSINTPTINTKVDDKKESKERTPKSATAPKPRRKKSKMVNSTSTPAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSF5</accession>
    <name>X0CSF5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSF5"/>
    <dbReference type="eggNOG" id="ENOG502T5HS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1133510_0_0_1"/>
    <dbReference type="OrthoDB" id="5329399at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936579" evidence="1">
        <location>
            <begin position="21"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="224" mass="24323" checksum="EAFB6FBF19C6CCA5" modified="2014-05-14" version="1">MVAFNTLLTFAATLVPLVTGAALPTHEDSSLTRRQYQDKSWDAYHRQNGAFARQGLCLFYLDPSPRDGAWACGVYCKSDRTKICTTVHPSKFTNDMLGANPDGERYAIGQCQCDTSAADFLATATVDFTARGLDKGFREIGSVTCEIMVNVMKEAVFASTYAIPGVGPVATAARTVAKGVKLASKTQGGKDMWTDAVKESCNFRRDEELLNKGFGIFEGAPDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSH8</accession>
    <name>X0CSH8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein transport protein sec16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_02611</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SEC16 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1913">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001147_1_0_1"/>
    <dbReference type="OrthoDB" id="8918678at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09233">
        <property type="entry name" value="ACE1-Sec16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1030:FF:000008">
        <property type="entry name" value="Protein transport protein sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024340">
        <property type="entry name" value="Sec16_CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024468">
        <property type="entry name" value="Sec16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12932">
        <property type="entry name" value="Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12935">
        <property type="entry name" value="Sec16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec16 N-terminal" evidence="14">
        <location>
            <begin position="236"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Sec16 central conserved" evidence="13">
        <location>
            <begin position="960"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="12">
        <location>
            <begin position="1138"/>
            <end position="1441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="701"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1439"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1505"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1580"/>
            <end position="1909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="305"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="326"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="394"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="547"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="580"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="618"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="647"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="714"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="768"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="889"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="915"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1463"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1505"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1689"/>
            <end position="1715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1716"/>
            <end position="1725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1803"/>
            <end position="1827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1856"/>
            <end position="1879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1892"/>
            <end position="1901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF12935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK97400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1909" mass="203428" checksum="5BBAF9D5B6277111" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CST5</accession>
    <name>X0CST5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1754-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CST5"/>
    <dbReference type="eggNOG" id="KOG3410">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098435_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013865">
        <property type="entry name" value="FAM32A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13282">
        <property type="entry name" value="PROTEIN FAM32A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13282:SF6">
        <property type="entry name" value="PROTEIN FAM32A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08555">
        <property type="entry name" value="FAM32A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="14879" checksum="42F6037049A5D924" modified="2014-05-14" version="1">MGSDDYAAVGGGGALKLKGAKIHKKKKKRDKTDLEKNLDTGNKDEEKRKKKDREEQEPHDEDDEDKPEVQKTEAQKRHEEIKKKRLLKLAESSSSRPELLKTHKERVEELNTYLSRLSEHHDMPRIGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUX1</accession>
    <name>X0CUX1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase I subunit rpa49</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03804</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUX1"/>
    <dbReference type="eggNOG" id="KOG4183">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034953_1_0_1"/>
    <dbReference type="OrthoDB" id="532500at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009668">
        <property type="entry name" value="RNA_pol-assoc_fac_A49-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14440">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06870">
        <property type="entry name" value="RNA_pol_I_A49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="438" mass="48849" checksum="767B0F826A22EDD0" modified="2014-05-14" version="1">MGSEKRKRSGDSTKPKKKVVIDAPPSSATVSSVLRPKFCPPVIATAVGFQVPKNIPFHSYAPKNGAKSKGKQPESAAEKDFLLHSNAHRSMDYTVKSDEPRGKKPALNHFLGIYDPKTGKLEVVEAKKMTMRASVRARQGAAATSGQRDNSQTMLQLKTDLGQTFGTKKAKKAIQENVLNAIAPQKKAGEEPAKIDAAARAMLNSVGEVTSTMSSREELQAVVDAAKPVPIANMEATEIQDVYDPKKIIGADILKLVPVREWQEKVQHKESIQVPSRFVAARVNRVAGNEEAVDRLRVLRYFFFVLLFYLHSKPGKARGTRTIAPREKLREFLAPAPEAVIESIRRKFSDRGEMRKFHVDLLITHCCVFASIIDNFEVDTQNLRDDLKIDQKTMNAYFQEIGGRVKHVTNKDTKQQVSVARLTLPLNFPKQRQFAPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVC1</accession>
    <name>X0CVC1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01343</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVC1"/>
    <dbReference type="eggNOG" id="KOG1502">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_1"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="7"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK98415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="341" mass="36370" checksum="4DFC7B718E7518DA" modified="2014-05-14" version="1">MSSKPIVLVTGANGYIAGPVVEAFLKAGYAVRGTVRSKSSADPLLRALSSYDKDLEIVEVPDIVASGAFDAAVKGVHAIAHLAAGVSLSFTDPEPVLEVAIQGTLGVLESAITESSVKSVVLMSSIASIINGSKEAPARFTEADWNDEALAAVKKLGKESPSPLIYAASKVASERAFWKFRDERSPSFTMTALNPVFVMGPQPGLESISKIGGTTAFIWQILSGQDIPKPLTPNPGYVDVRDIARVAVFSVDHPDKVNGERFLLASGLVPPQAAADVLRKAYPERQDIIKAGNPGQGYFPGYEFPEERFLDASKAVKVTGQDFYPVEQTITDTAKSLEKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWM4</accession>
    <name>X0CWM4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_09627</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWM4"/>
    <dbReference type="eggNOG" id="ENOG502S50Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018825">
        <property type="entry name" value="DUF2427"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF4">
        <property type="entry name" value="DOMON DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10348">
        <property type="entry name" value="DUF2427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937277" description="DOMON domain-containing protein" evidence="9">
        <location>
            <begin position="21"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="10">
        <location>
            <begin position="62"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="11">
        <location>
            <begin position="219"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="180"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK86877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="391" mass="41649" checksum="FDE8A135A517E24B" modified="2014-05-14" version="1">MKSTFSASLAVLSAASSALAVTSSFCPDNGNVCFRWGIPEASASAGSGSFYFQIKAPTSAQWAGLGTGSQMAGSNMFIIYQDGNGNVTLSPRRGVGEVMPQYTKRSGLELLDGSGIKDNQMIANIRCNNCVDLSLKGTSSWIAAWKNGNSLDSTSMEERISEHDTHADFSVDFSKATMSSDSNPFTGSNENTNSNSGSSSGGAVTQNGSGSPSKTVLRAHGIIMSIVFIAGYPLGAILMPMLGKWLIHAGWQVVMLLLMWAGFGLGYVYARDGGYWGKQAHTRMGTAVCALMTLQPVLGYMHHRYFASHRKRGVVSHVHVWFGRALIIIGIVNGGLGLQLANSSTAYIIAYSVIAGIAAILYLAAAFIGERRRNASRAKQISPQMSQEEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXG3</accession>
    <name>X0CXG3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXG3"/>
    <dbReference type="eggNOG" id="ENOG502RKS2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2740142_0_0_1"/>
    <dbReference type="OrthoDB" id="5074162at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="71" mass="7895" checksum="12DC170ECF5741CB" modified="2014-05-14" version="1">MASMDHIDAARARLHSLFNASFEKLDDTLSNAMYYVLSIIGTNEGPAVNNFVEVHVPLPSQRGDTFIKDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXK3</accession>
    <name>X0CXK3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit TIM44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_09431</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim44 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXK3"/>
    <dbReference type="eggNOG" id="KOG2580">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020932_2_0_1"/>
    <dbReference type="OrthoDB" id="10265990at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.240:FF:000002">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039544">
        <property type="entry name" value="Tim44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim44-like" evidence="14">
        <location>
            <begin position="395"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="84"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="108"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK87167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="555" mass="61717" checksum="D30EB2E98B6EE4E9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYH3</accession>
    <name>X0CYH3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-aminopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_00045</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S12 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYH3"/>
    <dbReference type="MEROPS" id="S12.002"/>
    <dbReference type="eggNOG" id="ENOG502QQBX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_0_4_1"/>
    <dbReference type="OrthoDB" id="5946976at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027279">
        <property type="entry name" value="D_amino_pept/lipop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012856">
        <property type="entry name" value="DAP_B_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009622">
        <property type="entry name" value="PRK13128.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF11">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07930">
        <property type="entry name" value="DAP_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50886">
        <property type="entry name" value="D-aminopeptidase, middle and C-terminal domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="5">
        <location>
            <begin position="9"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="D-aminopeptidase" evidence="6">
        <location>
            <begin position="354"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK99575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="536" mass="58896" checksum="3F8A540CE403B0BF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZN0</accession>
    <name>X0CZN0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZN0"/>
    <dbReference type="eggNOG" id="ENOG502RPK5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_806634_0_0_1"/>
    <dbReference type="OrthoDB" id="5093056at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="359" mass="41425" checksum="7939620D1ECC4177" modified="2014-05-14" version="1">MERQLDNNIKCLRGLKAKSKKIPKRRTKFQGIKLPKPPQKPIIPARKALTRRGPRKSKSLDTDRRNKRLERTKRQLEKENVSALNETSKLRQDLRKQRRALAKERSESARKSLEIDLLRNDNITAHQNLNDRQTALKEAQERCRELEASLRSQNEATHAAQDQYAGESPITVDGSNFDEVGDLDDMIPSKPSSPDEKGNKFNEYERHIATPPPSQRRISSVTTAATPPETPAAGPSNNLILLGGYFPVVEDENFDDEMKEIFRGHLYVGRVFRRFREFLETGHENSWYCVQDIVKYGYSFGSWNDNICENGEHDGVRCSQVKVTVVDSIRRLRFKHDEDVRPSNWQDLYPERLVTTRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0H4</accession>
    <name>X0D0H4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4246 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0H4"/>
    <dbReference type="HOGENOM" id="CLU_2184066_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="109" mass="12620" checksum="3F9C846345A6BAC7" modified="2014-05-14" version="1">MFDAVLDELRHKADIFEQAGLIPVMDFCIAALKSNKLLTDELVAEIKSAVAPLENVPEEQKDWQPGTHHQMLDLVHREGIRDELMEERDARVKEFDSELISVDYRFCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1Q9</accession>
    <name>X0D1Q9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alcohol dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="9">1.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_08401</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a primary alcohol + NADP(+) = an aldehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15937"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:15938"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:15939"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.2" evidence="9"/>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1Q9"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_2_1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008106">
        <property type="term" value="F:alcohol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000158">
        <property type="entry name" value="Zinc-binding alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="12">
        <location>
            <begin position="11"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK88617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="360" mass="39246" checksum="2C7445E8EE670675" modified="2014-05-14" version="1">MSVPDKFQGFQSPSAEHWTDFQKNSFEPRPFGEYDVDIKIECCGVCASDRHTISGDWGGCPYPLAVGHEVVGKVLRVGDKVTLAKVGDRVGAGAQVWSCLECRQCKNDNETYCKHQIDAYGADYLDTGFKTQGGYSSHSRVHEYWVYPIPEALSSTQAAPMLCAGITVYSPLKRLGAGPGKKVGIVGIGGLGHYGVLFAKALGAEVWAISRSRAKEADARKMGADGFLATGEKDWTEGHKMSFDIIINTATSFEGFALSEYLSLLDVHGHWNSVGLPGGDGISIRNQDFITNGCYIGTSHLGSRREMLEMLQLAADKGIKSWIEEIPISKEGLQQAMEALRTSSVRYRSCMTNYEEAFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1S0</accession>
    <name>X0D1S0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08410</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1S0"/>
    <dbReference type="eggNOG" id="ENOG502R05R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020412_1_0_1"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06185">
        <property type="entry name" value="PDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46696">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46696:SF6">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="421"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="6">
        <location>
            <begin position="652"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK88627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="738" mass="82314" checksum="B926449D61FCDAA9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3C4</accession>
    <name>X0D3C4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Casein kinase substrate phosphoprotein PP28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3C4"/>
    <dbReference type="eggNOG" id="ENOG502S9UA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068528_0_0_1"/>
    <dbReference type="OrthoDB" id="21120at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019380">
        <property type="entry name" value="Casein_kinase_sb_PP28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039876">
        <property type="entry name" value="HAP28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22055">
        <property type="entry name" value="28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10252">
        <property type="entry name" value="PP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Casein kinase substrate phosphoprotein PP28" evidence="2">
        <location>
            <begin position="139"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK97624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="256" mass="28341" checksum="70AB60271066408F" modified="2014-05-14" version="1">MAPGGPPGGGSRGRGGKFRKPARGGGKKFSRDIRPLDADGNEVSMWAVDPDKKDDDSDEEESSEEESSEEEEDSEEDSGAGPSQEQTQEQSREARKAEKKARKEAAIARQKAKTVEVGDLPSSDEDESESEEDDDMPANPNHSKKARKQAASSGVDEITEGVENLQAAPSRREREALEAAAAKERHMRLTAQGKTDESRADLERLKEIRERRALDAARRQAEREEREEQEKIKKAEFEAKEARRREAAAGKKGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3N9</accession>
    <name>X0D3N9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_07924</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3N9"/>
    <dbReference type="eggNOG" id="KOG3745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008002_1_0_1"/>
    <dbReference type="OrthoDB" id="125856at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048625">
        <property type="entry name" value="Sec10_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20667">
        <property type="entry name" value="Sec10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec10 N-terminal" evidence="6">
        <location>
            <begin position="57"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec10-like alpha-helical bundle" evidence="5">
        <location>
            <begin position="195"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK89267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="847" mass="95352" checksum="91ED9F36DE6996C1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D691</accession>
    <name>X0D691_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alkaline ceramidase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_07031</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D691"/>
    <dbReference type="eggNOG" id="KOG2329">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063293_1_1_1"/>
    <dbReference type="OrthoDB" id="187171at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187:SF1">
        <property type="entry name" value="ALKALINE PHYTOCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK90152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="24764" checksum="DC338F92EAB26747" modified="2014-05-14" version="1">MYGSRSRSRGLLDPKWDFMSVSLLILGFGSFLFHATLRQTLEFVDELSMLLLSWSMLRSLVILRQSPQNIRYISIVLAVFFISFSVFYVRSAKIIYQVIGFWVSLIVIGVRVRYLFHWAKPTFPEENVRDWSIRVWTATFTCLFGYFIWNLDLEFCAELRNFRQRIGLPWAWLLEFHGWWHILTALGASQFMNVVREVREEVSREKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7F4</accession>
    <name>X0D7F4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502RM9G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_244106_0_0_1"/>
    <dbReference type="OrthoDB" id="5383572at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.16.10">
        <property type="entry name" value="Hedgehog/Intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1341"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1374"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1401"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1568"/>
            <end position="1597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1586"/>
            <end position="1596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1627" mass="181971" checksum="EA035F70071A6512" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBG0</accession>
    <name>X0DBG0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Plasma membrane proteolipid 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_00840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBG0"/>
    <dbReference type="HOGENOM" id="CLU_107649_1_2_1"/>
    <dbReference type="OrthoDB" id="2152119at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF42">
        <property type="entry name" value="UPF0057 MEMBRANE PROTEIN ZK632.10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939897" description="Plasma membrane proteolipid 3" evidence="6">
        <location>
            <begin position="19"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXL00884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12347" checksum="035EA62C4F331688" modified="2014-05-14" version="1">MGAISAVFLILITIFCQSQTPPDRTMQSKTNVVAVPPIGVWAVAGCGMDLFINICLTLLGFLPGHIHAFYLEYIYYDRREQAREGRFATGPAPGIYSDNVQTGGQGYGTMGRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCP4</accession>
    <name>X0DCP4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">alcohol O-acetyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.84</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Alcohol O-acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_00843</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aliphatic alcohol + acetyl-CoA = an acetyl ester + CoA</text>
            <dbReference type="Rhea" id="RHEA:17229"/>
            <dbReference type="ChEBI" id="CHEBI:2571"/>
            <dbReference type="ChEBI" id="CHEBI:47622"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.84"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.84" evidence="6"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCP4"/>
    <dbReference type="eggNOG" id="KOG1838">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032487_1_0_1"/>
    <dbReference type="OrthoDB" id="5954035at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008126">
        <property type="term" value="F:acetylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004026">
        <property type="term" value="F:alcohol O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051792">
        <property type="term" value="P:medium-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051793">
        <property type="term" value="P:medium-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000137">
        <property type="entry name" value="EEB1p Acyl-coenzymeA:ethanol O-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050960">
        <property type="entry name" value="AB_hydrolase_4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794">
        <property type="entry name" value="ABHYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794:SF63">
        <property type="entry name" value="ALPHA_BETA HYDROLASE 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="9">
        <location>
            <begin position="123"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00050620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00066969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00080774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005211-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXL00890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="431" mass="48419" checksum="49BFFD30FC00BC47" modified="2014-05-14" version="1">MEWLGHAELNFTHAPSPRKVQEKDGNVTDLLSICEKATPPCRLNPLLFNGHLQTMWTATKPAGPKIYYKRKIFDADHKIYHGTFAVDFAVEPFEAPEDPSLSRRTAYFTPEEFEHIGSDDHKPMLVVLHGLSGGSHEIYLRHTIAPLIGEGGWEVCVVNSRGCARSKITSGVLYNARATWDIRQTIKWLQKTFPNRPLFGLGFSLGANMLTNYISITSPNLGSEGPNCVLKGAVVCSNPFNLEVSSKILQNSYIGKEVYLRVMGSALKELAATHRTELEKYSKIDVEAVMNITYLYEFDRLIQCPSWGYPTESAYYRDASSVDSILSIEIPFLAVHSTDDPIAVKEAIPYEEFKQNPNTVLLTSSLGGHLCWFETSGDRWFTKPVANFLNHLAFKTDLNDLRPLVNPNNNDHLADGHGYIPMRRKLVIVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0DLT2</accession>
    <name>X0DLT2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NECAP PHear domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DLT2"/>
    <dbReference type="eggNOG" id="KOG2500">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069884_0_0_1"/>
    <dbReference type="OrthoDB" id="10265489at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13228">
        <property type="entry name" value="PHear_NECAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000465">
        <property type="entry name" value="Adaptin ear-binding coat-associated protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012466">
        <property type="entry name" value="NECAP_PHear"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847">
        <property type="entry name" value="ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847:SF9">
        <property type="entry name" value="NECAP-LIKE PROTEIN CG9132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07933">
        <property type="entry name" value="DUF1681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NECAP PHear" evidence="2">
        <location>
            <begin position="17"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="255" mass="27119" checksum="8DA3FBDE6D4EC07F" modified="2014-05-14" version="1">MELLDPATGAALPNDAIQRILFVANAVHVYNIPPLTSTKGYSASTWTAEPQRHIFTARLRVVETAYESESSTNKLKVDAVLEDASSGQLFAAAPYTAPGVVEPVLDSSRFFAVTVRDPQGRKAILGIGFEERSEAFDLSIALQEARKALGWEGEQSKPAATKEKEEHRDYSLKDGETITVSFGGSKFGRRKQQDSSSGSGAGGDLQSFALPPPPAGPSSSGGFSLPPPPSANAVKQQKQSAKDLGFDDGQFGEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0DLX4</accession>
    <name>X0DLX4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DLX4"/>
    <dbReference type="eggNOG" id="ENOG502S2ZP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051199_2_0_1"/>
    <dbReference type="OrthoDB" id="18530at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368:SF1">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005717926" evidence="2">
        <location>
            <begin position="22"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="296" mass="32344" checksum="906083315148ED23" modified="2014-05-14" version="1">MIAPIAWAVVALGALTPLVTANPEDGLPSYHYGAPIPVECMNRNSETGEHVENEKHEIEWKPFPVCNETGRPLEFNYGTEGEVNCTIAMIDDPFFHLLEFYIHSDAPLSCRIPARPAAEVEVVGEKVPEREYVPVVFALAGTLQLSHIHISTHMNVLLHSTPKHHTHAHDSGVLDSAIAYSTSPLHHLQGSHTRKLVIGDPLPLSLSVRWFPTPALPKTEGKVEWQGLGGHIYASTVFYSLVSFGAGVLCATMYTLGVILPRRLKGRALGGATPLGYGVNTMGNGWGYSKQNKRMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0DM60</accession>
    <name>X0DM60_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xaa-Pro dipeptidyl-peptidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DM60"/>
    <dbReference type="eggNOG" id="ENOG502QZDY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015590_2_1_1"/>
    <dbReference type="OrthoDB" id="416441at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF10">
        <property type="entry name" value="COCE_NOND FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="2">
        <location>
            <begin position="319"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="592" mass="67244" checksum="83361C9BD721D9BC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0DQB2</accession>
    <name>X0DQB2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DQB2"/>
    <dbReference type="eggNOG" id="ENOG502TCM7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010785_1_0_1"/>
    <dbReference type="OrthoDB" id="5244857at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="692"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="623"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="763" mass="83673" checksum="CC2DF03B4EDABE9E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0DRG0</accession>
    <name>X0DRG0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_02270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DRG0"/>
    <dbReference type="HOGENOM" id="CLU_915415_0_0_1"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF15">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="63"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK96862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="298" mass="33073" checksum="8A0459FA397856DF" modified="2014-05-14" version="1">MNTTKWRISKACQECRAKKIKCNGETPCQNCSMRNLSCVYREKARNRTRKVKPRTAAYETIMSHDAMESTSLEPSDEGTVPPTPNADDAASVGPTGSVMDSERSLTHNSVAATHRASPSCFLQLYYGPSSNFALLNSIYHQIAGTCPNDPPSRSGIVEEVGPGLDLFSHRRLFFGDLADNQRPSSVPDDCSAMLIDPDTAHRLLERYLLTYWHGLPIMSKDHYRRRLSALYQPPGIFDYDAPETIIIMLAVGLGASMTGEEAIADFLFQKTKQGVAKLDEVVNMQMVQIHLLMISHTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0DSP6</accession>
    <name>X0DSP6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="19">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">FOQG_02530</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 19">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="19"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000846_3_1_1"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000048">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000067">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000009">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF5">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 18 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 19" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="542"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="572"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1097"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1130"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1174"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1208"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1233"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1263"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="21">
        <location>
            <begin position="175"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="22">
        <location>
            <begin position="1067"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="295"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="384"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="16">
        <location>
            <position position="631"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="631"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="631"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="632"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="633"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="633"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="744"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="788"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="822"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="851"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="932"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="933"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="934"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1014"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1020"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1040"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1043"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1044"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1044"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EXK97277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1303" mass="144685" checksum="A4A3CB2D22CE849D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0DTA2</accession>
    <name>X0DTA2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">30S ribosomal protein S10e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02667</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DTA2"/>
    <dbReference type="SMR" id="X0DTA2"/>
    <dbReference type="eggNOG" id="KOG3344">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089349_0_0_1"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000025">
        <property type="entry name" value="40S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="93"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK97482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="165" mass="18723" checksum="4E04F7452785C55E" modified="2014-05-14" version="1">MLIPKADRKKIHEYLFREGVLVAQKDFNLPKHPDIDTKNLFVIKALQSLNSRGYVKTQFSWQYYYYTLTPEGLDYLREWLHLPAEIVPATHIKQQRSHAPPRGMLGEGERERRPFGRGRGGDRGDREGGYRRRDAGEGKEGGAPGEFAPQFRGGFGRGRGAAPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0DY26</accession>
    <name>X0DY26_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thioredoxin peroxidase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Thioredoxin-dependent peroxiredoxin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_01727</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DY26"/>
    <dbReference type="eggNOG" id="KOG0541">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072440_1_1_1"/>
    <dbReference type="OrthoDB" id="195498at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000020">
        <property type="entry name" value="Peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="16"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="8">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00079296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR637944-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK99072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="167" mass="18015" checksum="C3610F6EAF941842" modified="2014-05-14" version="1">MSELKAGDSFPEGVWFSYIPPSPETSEFTTCGTPVPFNASQEFKNKKVVLVSIPGAFTPTCSGSHIPSYLEHVDKIKAKGVDQVIVIAVNDPFVMSGWAKANGITDDKILFMSDKDAKFSQTIGWNIGERTGRFAIIVDQGKVVYAARDEEPGSIEKSGALGVLAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0B239</accession>
    <name>X0B239_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">endo-polygalacturonase</fullName>
            <ecNumber evidence="3">3.2.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Pectinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_19426</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(1,4-alpha-D-galacturonosyl)n+m + H2O = (1,4-alpha-D-galacturonosyl)n + (1,4-alpha-D-galacturonosyl)m.</text>
            <dbReference type="EC" id="3.2.1.15"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.15" evidence="3"/>
    <dbReference type="EMBL" id="KI979800">
        <property type="protein sequence ID" value="EXK75811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B239"/>
    <dbReference type="eggNOG" id="ENOG502QTAW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040116_0_0_1"/>
    <dbReference type="OrthoDB" id="1546079at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000002">
        <property type="entry name" value="Endopolygalacturonase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050434">
        <property type="entry name" value="Glycosyl_hydrlase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884:SF1">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936206" description="endo-polygalacturonase" evidence="17">
        <location>
            <begin position="18"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="active site" evidence="14">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00083621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK75811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="381" mass="40115" checksum="F0A8B591C7E0E5CD" modified="2014-05-14" version="1">MRFSLLLFGSFIASAFAGHSHSSSKSHHPRSLPESDSSSDSHPTPGGCNFTTADTAMQHKSSCSTIILNNIKVPAGKTLDLTKLKDGTTVIFKGVTSFGYAEWLGPLITISGNGLTIEGDAGHCINGQGRRYWDGKGGNGGKKKPKLLALHNVHDSIVQNLNIKDTPVQAVSINTVTNLLVKDVHIDSSLGDKLGGHNTDGFNVGKVDGLVIDGAVVENQDDCVAINSGKNITFTNGHCSGGHGASIGSVGNKSSNIVENVLISKTMIENSENAIRIKTIAGATGSVTDVTYEDITLRDIDKYGMVFRQDYLNGGPTQQPTKGVPMTGIRIKNVTGTVKPAGKNIFILCANCKDWTFTNIDITGGQSKEKCVGVPAGAFCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0B369</accession>
    <name>X0B369_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979580">
        <property type="protein sequence ID" value="EXK76166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B369"/>
    <dbReference type="HOGENOM" id="CLU_096858_1_0_1"/>
    <dbReference type="OrthoDB" id="5099098at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="171" mass="19019" checksum="45FEAD433E618D61" modified="2014-05-14" version="1">MPCFNCEKRGLSCLVSPMSSGRCDSCIKADYSCDSEGFSVAAARKVAKEQRRLEEAEEKVEGEFMLLQAESTRIHNEMNAKLAQITRLRRQRRQVESKGLDMLRRGLNSIDELEQAEKDENAAFEQAISEGTFHDWSAIVEQSEWDSLGLGQFIDPPFVVGGSSSGVAEHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3P4</accession>
    <name>X0B3P4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979454">
        <property type="protein sequence ID" value="EXK76725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3P4"/>
    <dbReference type="HOGENOM" id="CLU_2263910_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="103" mass="11232" checksum="CA0CE2E13BE9C4FB" modified="2014-05-14" version="1">MKREQLGFEYKYMMDMNMTPHGPMGSLTPSNSLGMYGYSPDGSIGAASFMMTPTHSLSGSEAAETGSSWSCADDRPISFFPNKQLFSGFDSFDLGRHSQSPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4C4</accession>
    <name>X0B4C4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_18659</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658700">
        <property type="protein sequence ID" value="EXK76606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4C4"/>
    <dbReference type="HOGENOM" id="CLU_001248_3_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046700">
        <property type="entry name" value="DUF6570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20209">
        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6570" evidence="3">
        <location>
            <begin position="292"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Helitron helicase-like" evidence="2">
        <location>
            <begin position="646"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK76606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1158" mass="131950" checksum="5841C8709DD511A6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5N5</accession>
    <name>X0B5N5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="18">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">FOQG_17855</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="function">
        <text evidence="17">This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports the calcium to the vacuole and participates in the control of the cytosolic free calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 18">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="18">Membrane</location>
            <topology evidence="18">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15 18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="18"/>
    <dbReference type="EMBL" id="JH658608">
        <property type="protein sequence ID" value="EXK77435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5N5"/>
    <dbReference type="HOGENOM" id="CLU_002360_9_3_1"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000039">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000028">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000031">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000018">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 18" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 18" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13 18" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 18" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="414"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="874"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="907"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="949"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1024"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1057"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1086"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="22">
        <location>
            <begin position="131"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="20">
        <location>
            <begin position="235"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="21">
        <location>
            <begin position="901"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00059328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EXK77435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1169" mass="127804" checksum="7B0C23FE98B65629" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6V1</accession>
    <name>X0B6V1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_17784</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658598">
        <property type="protein sequence ID" value="EXK77501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6V1"/>
    <dbReference type="HOGENOM" id="CLU_001640_0_0_1"/>
    <dbReference type="OrthoDB" id="8061355at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000335">
        <property type="entry name" value="ATP binding cassette subfamily A member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="430"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK77501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="752" mass="82625" checksum="505640F9C95C24E5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7Q9</accession>
    <name>X0B7Q9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658570">
        <property type="protein sequence ID" value="EXK77796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7Q9"/>
    <dbReference type="HOGENOM" id="CLU_017138_0_0_1"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="767" mass="87573" checksum="6979E16FCA1BC17A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7Z3</accession>
    <name>X0B7Z3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Malate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658533">
        <property type="protein sequence ID" value="EXK78240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7Z3"/>
    <dbReference type="HOGENOM" id="CLU_067863_1_0_1"/>
    <dbReference type="OrthoDB" id="1859733at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF3">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936777" description="Malate dehydrogenase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="26150" checksum="024DA4B4AB4E05A4" modified="2014-05-14" version="1">MLARFFFVLPSAALALASPPGHKLCPSQSGMPTKPTPVLPSNGGGSELPEPSEDVSLKHIALGFGIQNYTCADTAASPTPVGALAVLYDVTHLYPGQGHSSLTQDEWASLPGDILDTLKVPLNLNEKGTGASLVKPFPRKQDLKIRSLSKKIPYLGHHYFNAAGVPTFDLDKARQLLVAKKIGDIKAPASSPAGPEGTGAVNWLFLGDAGGSHGISYAYRVLTAGGASHGCKAKGADSTSYTAMYWFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9C8</accession>
    <name>X0B9C8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_16950</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658525">
        <property type="protein sequence ID" value="EXK78366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9C8"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000217">
        <property type="entry name" value="MFS lactose permease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF13">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="54"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK78366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="545" mass="59787" checksum="ADCCA58D4AA6893C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9Z4</accession>
    <name>X0B9Z4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Biotin-protein ligase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658514">
        <property type="protein sequence ID" value="EXK78591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9Z4"/>
    <dbReference type="eggNOG" id="ENOG502SI15">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057558_1_0_1"/>
    <dbReference type="OrthoDB" id="10250105at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019197">
        <property type="entry name" value="Biotin-prot_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09825">
        <property type="entry name" value="BPL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin-protein ligase N-terminal" evidence="1">
        <location>
            <begin position="85"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="250" mass="26818" checksum="54714AEFE64EC7B0" modified="2014-05-14" version="1">MAIISYGVSATLGAQARPKAVVYRGPASSEGCPEGVRDLLVSSPSNFEVVFAGPNEPVDVVEALKGATVYAHGGGPNWSKAYRSTKKYEKAIQEFVKSGGHYLGFCLGAYLAGPVNGYNLLPKGVNTEQEIKRRRAQVKGEEDTVINVDWTFESGTTEDKRWLYFQDGVVIRGMDESKPGKVVGRYSANGDVAASITPYGKGSVGLVGPHPEADDTWYDGAGIKNPEGIRLDIGHDFVEATVHAGSYKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAI8</accession>
    <name>X0BAI8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658503">
        <property type="protein sequence ID" value="EXK78776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAI8"/>
    <dbReference type="HOGENOM" id="CLU_681583_0_0_1"/>
    <dbReference type="OrthoDB" id="5077428at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="498" mass="54160" checksum="4DD4A1CDA1E58B7A" modified="2014-05-14" version="1">MDHMLSVGSLPWFSVDEFTGSNQPMGPKQQSHPREANAELCELSTEASMAGNVIDFVPGMSASMTLGYTLARLGLPLDIQGIMQGFSFGIADAFSYNNMGNLDYFSNPVPNGNGVVSSQTGVQSLSGQLWGISGSPHCAEEHPTGYKNGEGFFGFLASRLTEEPAGNLQNGDTCETDLSSILQEQCEGITAGSLSPVNPGSQDDNLPEMLTETQSEGIRYGQPDAFSDSVETFSGNVYSPSCRAGSLTPPQDTISFTQGPESNQEAVTSSASCINPVGCHTQSPEPVVPGTTERPSSPMRSSIDIIDLTLDSDETPAATATPNTNSATSRTAHAVAEGLPLMPNGMNRRTESSRSKRRNHQKRKRCHEDVQSFPEIVTLRVISVKVEKENRDGFMETVEFIRHKSRKWKAKESNEECIIKLREVVSFEMMVQGGSLGRINIHKSEDADTYKGTEPLMEYMVVLSKDEADKVLDDPEKSLGTRCHLLQEQNRSKTLRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCN1</accession>
    <name>X0BCN1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658454">
        <property type="protein sequence ID" value="EXK79920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCN1"/>
    <dbReference type="HOGENOM" id="CLU_2979128_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="65" mass="7464" checksum="E42875BBC36F1C28" modified="2014-05-14" version="1">MDSYYSPMRKHNGMQDKRAVYTYGDVSRSLAFFLGDVELCWQNSSFSRNMPFATWTNVRAAVSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCU0</accession>
    <name>X0BCU0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979344">
        <property type="protein sequence ID" value="EXK79606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCU0"/>
    <dbReference type="eggNOG" id="ENOG502SU5G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059039_1_0_1"/>
    <dbReference type="OrthoDB" id="4770059at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="300" mass="31740" checksum="73B9AFCB22B05FE4" modified="2014-05-14" version="1">MPTSTEFFGVTAYNLGPLTTTFSAPSACATGTDHHVIVNASEPEMVWGYPTCGFQDRGSCMPSGKSYDSLRSVTTPLNRAWYHYYSPGIACPSGWTTAGTMIKEGESSLSVSGVFSSRIQASTTGAVQLEPADFWAEIMNVSETIAYCCPSDYVANPAGHCFSTVGPRSEFNYSSMCYTPAPVDIITVTSLDGASLTQPLISFDVLTTPASTYLDDRLLTQSRYSSDFVVATWVPAVPLIHQQSDVDEADDEDDEENDGGDDGDGEDTDGNAASTKTPGNGIVSVLGLTLGALAGMGMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDL0</accession>
    <name>X0BDL0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979480">
        <property type="protein sequence ID" value="EXK76579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDL0"/>
    <dbReference type="HOGENOM" id="CLU_2638153_0_0_1"/>
    <dbReference type="OrthoDB" id="5088420at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="77" mass="8460" checksum="2C66BBF2882D2565" modified="2014-05-14" version="1">MLYHKFVEVLDSHDSGACLGPPIEGHHRPCQGRNSPYTRVASTVADGPQDERLIASTDADPEFRKGLTLGDDVKLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDY3</accession>
    <name>X0BDY3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658447">
        <property type="protein sequence ID" value="EXK80360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDY3"/>
    <dbReference type="HOGENOM" id="CLU_783121_0_0_1"/>
    <dbReference type="OrthoDB" id="5234017at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="354" mass="39164" checksum="2482BA22129CF75D" modified="2014-05-14" version="1">MSSKRRATTTAQSDAFRNAIASCEGKLKKLKTIYKNDLHRQQCRSLIQEIHSKLEAAVNPAAKLPEESVIHVKTTKASAKARRINRPSTRTSPRRSEVLVAPIPEQIYLAYCHMSKSWFAIKSYGLHESIPACFHCNDEGHFIWKQGYKDGSPLISGRQFPVMFFSGASTFKQERYGWVAAKDLQKFDPQGYQASLVPHYNAVLAFIAERNCPSPGNIARELEEVAEAEITGPTLTDIEPLAATSSCSAGAQEIGTRRDLNPNVPGRISCEQREVASAAMELLTESTSIYLTQPTSASSENSPTFYNLPPLNPAPAGNIKSLPTIRLLTDRIPINRHSGNYTTATYRDVVPRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEB3</accession>
    <name>X0BEB3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658450">
        <property type="protein sequence ID" value="EXK80151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEB3"/>
    <dbReference type="HOGENOM" id="CLU_029475_0_1_1"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="317" mass="35020" checksum="8EAB25B49E7E0EB6" modified="2014-05-14" version="1">MTSSVVPRKYADYHLSPNRQPLPSISEFIRDTKPATCTHTPFSSVQTDSGLSLPLASIHRTLPKTGKNPSLHQLLSASPFPPRQHTLPAVSDPLPPPFASLPSPLPVSNCCQSPSVKAEILSQHHQPQQQKTQEPHPPFRQVHSHSAPPSLPPDPIYSQPRPLPPGQIPLAPYPTPPRNGFATQAGYDASVKRHPRSWSYRDSLSQISSSSRTILNCAEKYNRIACEQHGAHVILERLPTEWELSSMLSNMELIKRSLEHIEDFVQTSIQNERASEGAKMKEENHATVSVYALQPSSGTTGTTKRLAMPKLRPNPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEG4</accession>
    <name>X0BEG4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979436">
        <property type="protein sequence ID" value="EXK76879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEG4"/>
    <dbReference type="HOGENOM" id="CLU_038488_0_0_1"/>
    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="426" mass="47735" checksum="6A5C1EB9F4E87A52" modified="2014-05-14" version="1">MSKSLSDLLSQKPPSVPSPQPGAKDAPSQDPESSEGGNSITSQPTPIEVPSIAPNMEFATVNETGHQPPGTDSIVSNTLFQPMMPYSAAEFNFLGNLSRTEQLDPKTPLQMQQIPRIWNFDYQMGSQSYTDALVACPGGFTNRLGWVQSNSPFSDHIHILKRLLSSKVGTAARFVDAQSYRSIFQSVSTVWALFNSITRPDVMNWLSKTKFFHIIELTIWQILPCPYTFSRVQQQYRPTQLQVTLQGQYPCVIDWVPFPLIRDRLIQYHAANPSIDQIFCDAVSAYVVESHLSDLVIGCPPLKVYVRVTDLVISMAGDEGEDPDIVPTIPATNVQTLFTSPKHARLAFEHLKMDCGSSYYKVDPVFFEKYPELYTASDEKIAKGIPLKPEFQTTITRPVHLDNTTVGLYSNFIDFMFHVSNSLYYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI70</accession>
    <name>X0BI70_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Interferon-induced GTP-binding protein Mx</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_14061</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658426">
        <property type="protein sequence ID" value="EXK81531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI70"/>
    <dbReference type="HOGENOM" id="CLU_008964_7_0_1"/>
    <dbReference type="OrthoDB" id="415706at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="4">
        <location>
            <begin position="36"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="3">
        <location>
            <begin position="616"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK81531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="710" mass="81932" checksum="62683FAE3895B4C3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKH4</accession>
    <name>X0BKH4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_16388</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979352">
        <property type="protein sequence ID" value="EXK78979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKH4"/>
    <dbReference type="HOGENOM" id="CLU_011003_0_1_1"/>
    <dbReference type="OrthoDB" id="4060227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF17">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="153"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="474"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="704"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="705"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK78979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="825" mass="92269" checksum="90866DBA009B0345" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKR0</accession>
    <name>X0BKR0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_13154</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKR0"/>
    <dbReference type="ESTHER" id="fusof-f9gd15">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_3_1"/>
    <dbReference type="OrthoDB" id="6846267at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152098" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="31"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK82441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="551" mass="61318" checksum="054C126642AAB616" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKV3</accession>
    <name>X0BKV3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_16267</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979351">
        <property type="protein sequence ID" value="EXK79104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKV3"/>
    <dbReference type="eggNOG" id="KOG0253">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_52_2_1"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000171">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF5">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="75"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK79104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="548" mass="60088" checksum="2652C22E4D271C91" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKX4</accession>
    <name>X0BKX4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit DAD4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Outer kinetochore protein DAD4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_15853</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAD4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979346">
        <property type="protein sequence ID" value="EXK79548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKX4"/>
    <dbReference type="HOGENOM" id="CLU_177920_0_0_1"/>
    <dbReference type="OrthoDB" id="5516652at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013959">
        <property type="entry name" value="DASH_Dad4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28222">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28222:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08650">
        <property type="entry name" value="DASH_Dad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="15" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK79548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="72" mass="8330" checksum="A5149D9907D0ECB2" modified="2014-05-14" version="1">MESPHEHQQNLLLSRIITNVEKLNEAVVVMNKSLQDINIQNMNVELVAQMFKNYQSNVLFHLEATDNLKPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLP6</accession>
    <name>X0BLP6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_12603</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLP6"/>
    <dbReference type="eggNOG" id="KOG0022">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_2_1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08254">
        <property type="entry name" value="hydroxyacyl_CoA_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF5">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="21"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK83085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="357" mass="38916" checksum="7A16EFCC3BE52EA4" modified="2014-05-14" version="1">MTVTNSERVPATMFAWRKHKGSPKPVFEEVSVPKVSPNGILCKMLASGVCRSDHSLLTIEKQASWFQEKYILGHEGCGQIIEIGSNVQDNRLKVGDIVALHAVPGCGQDDCPECSRDLAQLCERGHHSGIGQDGFYAPYTAVDIRAAVKVPDGVSPAEAAVATDAVNTAFHAITRRGEVKKHETVFLFGLGGLGFNALQIVRYIGARVIVSDIRQELLDEAKALGIPEKDIVPVGKPPQDFIKENGLEGKIDTVLDFVGTHQTFEDAQHIVRRGGKLLCIGSLDTENTIHMKIGTRKRLSFIFSYGGQVRDLEKVLELIASGHISPRVETRKLPDFEEVLGALGEGKIKARVALLHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMN0</accession>
    <name>X0BMN0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_15724</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658463">
        <property type="protein sequence ID" value="EXK79699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMN0"/>
    <dbReference type="eggNOG" id="ENOG502QT5J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004835_0_1_1"/>
    <dbReference type="OrthoDB" id="5244761at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="376"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="456"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK79699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="919" mass="102525" checksum="C6AC664DE3B7110F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNA9</accession>
    <name>X0BNA9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_15100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658446">
        <property type="protein sequence ID" value="EXK80393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNA9"/>
    <dbReference type="eggNOG" id="ENOG502S19A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034346_1_1_1"/>
    <dbReference type="OrthoDB" id="5186469at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07062">
        <property type="entry name" value="Peptidase_S66_mccF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="entry name" value="LD-carboxypeptidase A C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237:SF4">
        <property type="entry name" value="LD-CARBOXYPEPTIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="MURAMOYLTETRAPEPTIDE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="LD-carboxypeptidase A C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LD-carboxypeptidase N-terminal" evidence="3">
        <location>
            <begin position="16"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="LD-carboxypeptidase C-terminal" evidence="4">
        <location>
            <begin position="217"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK80393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="359" mass="38873" checksum="BAAA1ADBE8303B16" modified="2014-05-14" version="1">MPSPIRAKHLKPGDRIAFISPSERINATLPAVVDRASALLTNKGYQVQTFFSEDKGIQSCIDNRLSEIRAAFSDPSISAIITTIGGTTFTELLPALIADKELHETIRANPKIVVGYSDISGLHWFLFGLTGLRTFYGPGAVPEIGEANDVNDKDTPLAFCVDNLLRAIASPEPLGQIPRSKFYAPRGAPFFATPESTEPPEVVKTTDWQWLRHGKAQGRLFGGCLTVVARLSGVSAIVPDWRGRIVFLETATNEDGTGGNPPHRVQAAFADLIAHGVFEDAAGLVVGRPYGYDSAEEREVYASIIKGLFCEGRLASKNFPILFNVDIGHTTPMITLPYDALAELDSETDTFAVLESGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNC8</accession>
    <name>X0BNC8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658453">
        <property type="protein sequence ID" value="EXK79979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNC8"/>
    <dbReference type="eggNOG" id="ENOG502QSKG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_0_0_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="32921" checksum="6DE6AEA32D6C7433" modified="2014-05-14" version="1">MSQKSPKSGSPRSPRSPQSQGPVATAAQALEVDDLPEGEEDDPGLGEDSESSTASITSSILHYRTINGRTYHSERGNAAYWGSNDERQSEAMDIAHHMFTLSQDGELHLAPLNDNIQKVLDVGCGTGIWAIDFADKYPGCEVIGTDISPIQPSWVPPNVKFEIEDFNQDWTFPPESFDYVHLRYLVGCVPDWDKLFEQAFKALKPGGWVESFEASAIIESDDDSVKPDSALAQWGPIFIKASKTIGNTFTVVGDELQRPGIEKAGFADVKQWDSKLPLNPFPKDPKLKEIGQFGELFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP75</accession>
    <name>X0BP75_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NDT80 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11724</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK83995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP75"/>
    <dbReference type="eggNOG" id="ENOG502RY09">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023693_0_0_1"/>
    <dbReference type="OrthoDB" id="4161727at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="138"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="301"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="431"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="314"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="450"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK83995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="651" mass="73509" checksum="BDB05DB9C93B12ED" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPT3</accession>
    <name>X0BPT3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxidoreductase dltE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPT3"/>
    <dbReference type="HOGENOM" id="CLU_010194_2_6_1"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669">
        <property type="entry name" value="5-KETO-D-GLUCONATE 5-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669:SF11">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="29693" checksum="E13C1BD272F89FAD" modified="2014-05-14" version="1">MAPLYKKALVIGATSGIGAALASKLVATGTKVVVVGRRRTRLESFVKTHGSDVSSAFHFDVTNLNGIKAFANTVIQSNPDLDCIIISSGVQRGFNFSEPETVNLSLLGDELTTNYTSVVHLTAAFLPHLQKELHGSIVYINATLGLIPAMSRTPNYNASKAALHAFVMDIRYQLRDSGCPLHIVEVFPPAVQTELHDERHQPDLVHGMEIGMPLAEFIEQMYDGLAKGSDQFAIGLGEDLFKEGGWEFQRGQMCDEARELLNYALVDYLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ57</accession>
    <name>X0BQ57_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11549</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ57"/>
    <dbReference type="HOGENOM" id="CLU_065192_1_0_1"/>
    <dbReference type="OrthoDB" id="5538558at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050563">
        <property type="entry name" value="4-hydroxybenzoyl-CoA_TE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793">
        <property type="entry name" value="4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793:SF39">
        <property type="entry name" value="THIOESTERASE_THIOL ESTER DEHYDRASE-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="30793" checksum="EF58B3DA7104CEA9" modified="2014-05-14" version="1">MSLRLLKRPINLASKAPISQLRLRSDQTPSNNDLPSFSSRWFADLQAQLKKFTSDHYPASCVQEAKRQLVSNEQNWLQLLAGQQGFLTDKKWRGLDNHQLLWGDMHGHVNNVMYNRYVETGRVHFIRQHSEDAAEHEKAQWDDLPTPRSLGLILRSITTEYKFPLEFPDHITVLYKLLEAPTNESTSLKMEAWILSEQYRRLAARCIDDTVIYDYTTAKKTALKPFMVDKFQETFSMQQANQRKYTDQAKQAIQAAEELQIKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRV5</accession>
    <name>X0BRV5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRV5"/>
    <dbReference type="OrthoDB" id="5126878at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="501" mass="56024" checksum="A339817B6E575B2B" modified="2014-05-14" version="1">MVGVSRSRACADCKRRRVKCDLTSPRCQRCTKAGIICRGIRNQPTLWVHRTPTKPNVSALSVIQSQQQTNWLSLLQRMRYQINSKETYDVPTFRSQAFSIAVSIYFPQGRYTTSEEDHSSTPSSWLKAVCNTEDPSEALDHSLVAFVAIQIRLSGEVGVSYDEAIELYNHALSKVIHVLDCPCIGNNDESLAAIVILSTCELFLFHASTSWNAHAQGVSEILRHRVVPEANTSSWNDLCRRLCVICVIQALSQKKPLNLEPNLWRKHIGPWAAPESFGALLDMAIDIPAVMAEAHTLALSNEKDREKLLRYVNLLIEKFHVLDDWRALVHRNIAARNQTPLFWSVPSRASNPADDGYPDRLFPFALIFSSVEGASPWILCSSIMLDILETILLLRGKLGSSDASSSLGETLDSYKEQGSPNQADADHIARMLCQSVEYCYRSENGTFGPQITCNAQATLLGYFAGRGMKRELEWCRAIKYMKGPGTSFGIDLMQFKPPPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUE5</accession>
    <name>X0BUE5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUE5"/>
    <dbReference type="eggNOG" id="ENOG502QRJE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017366_2_0_1"/>
    <dbReference type="OrthoDB" id="10261782at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038921">
        <property type="entry name" value="YOR389W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204:SF1">
        <property type="entry name" value="ENTEROTOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204">
        <property type="entry name" value="YALI0A21131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936001" evidence="2">
        <location>
            <begin position="23"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="567" mass="64428" checksum="A90F16E2DDD9055A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVD1</accession>
    <name>X0BVD1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">D-3-phosphoglycerate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10186</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVD1"/>
    <dbReference type="eggNOG" id="KOG0068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_3_1"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF264">
        <property type="entry name" value="HYPOTHETICAL D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="3">
        <location>
            <begin position="21"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="119"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK86140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="34934" checksum="2AF664308011DAA9" modified="2014-05-14" version="1">MAPSAVTDTPPEALPSGKPTVYVMDSFHPQVMAYCQENFNAITPDNPKHSQWRQEARYLLMRSSRLTAEDIKACPNLIAIGKQGVGIDKIDANACAAHGIKIFNTPGVNARAVAELVLTLATASARQVGSIVAKQSSGILVPKEKCSGLILHRKTIGILGMGNIGKCVASIFRGAFEADVIAYDPFLPADAWADIPHQRASSVEEVLESSDVITVHMPLTPQTRDLISYSEMKRMKRTAIVINTARGGIVNEDDLKRALSEGLIWGAGLDCHEEEPPSYERYHSLWEVGAVSTPHIGAATAETQMQTGMAAARYLLEFALNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVK6</accession>
    <name>X0BVK6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVK6"/>
    <dbReference type="eggNOG" id="ENOG502S689">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1214820_0_0_1"/>
    <dbReference type="OrthoDB" id="376826at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="228" mass="25652" checksum="B078032EAFE316F0" modified="2014-05-14" version="1">MKAISLAEAYCNPSRCKHIRSSYRPNEKVQHLLSYPVISDGVHTFDSGKYGQRSIQFGNAAYQTFAATATTWFQKPYQHLLPYIQKVDSLGDNILHYVNKQFPIIKKPTQELYNDTKGLVSLLYHKALEGRDHVLKVYDSEYKKNKQVGLVAHGKAAVTTVLGVSNEALLAQLPFAPEEGRGNQYRQLKFQSTEKTRLTSTLPQDLNGPRPLLLAMSSISAQRSLVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW08</accession>
    <name>X0BW08_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH dehydrogenase (Ubiquinone) 1 beta subcomplex 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW08"/>
    <dbReference type="eggNOG" id="ENOG502S52G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100674_0_0_1"/>
    <dbReference type="OrthoDB" id="2014058at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008699">
        <property type="entry name" value="NDUFB8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12840:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12840">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05821">
        <property type="entry name" value="NDUF_B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="172" mass="19597" checksum="553EC0138C02B1F0" modified="2014-05-14" version="1">MLPQRIVRASALRSTMTAARRLPTIQRRTFLPDQYTDKKVIDQKYPEPPSFSEAEDPGMNGGYINPPRIKRQFRDPHANWWDPQERRNFGEPIHEDNDVLGIFSPWEYTWTTAGPGAVMVGTFIAVFLSVTGVVYLNYPDRPAYPREFEGGLERELGGPGATRARMEGDEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW62</accession>
    <name>X0BW62_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW62"/>
    <dbReference type="eggNOG" id="ENOG502T55D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030365_0_0_1"/>
    <dbReference type="OrthoDB" id="5088573at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186:SF4">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="620" mass="71103" checksum="41C133F4D848270E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXQ3</accession>
    <name>X0BXQ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12031</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXQ3"/>
    <dbReference type="eggNOG" id="KOG0181">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_4_1_1"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03750">
        <property type="entry name" value="proteasome_alpha_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000048">
        <property type="entry name" value="Proteasome subunit alpha type-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="8">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="143"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK83668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="277" mass="30229" checksum="DF3CB8F9028C442E" modified="2014-05-14" version="1">MADRYSFSLTTFSPSGKLVQIEYALNAVNQGITALGIKATNGIVLATEKKSSSPLADQSSLSKISDITPNIGMVYSGMGPDYRVLVDRARKVSHTGYKRIYNEYPPTRILVQDVARVMQEATQSAGVRPYGVSLLVAGWDEGIEPEEENKTTEESEEKKVNRKTGGIHKGGPMLYQVDPSGSYYPWKATAIGKSATKAKTFLEKRYSEELELEDAIHIALLTLKDNIEGEMNGDSIEIGIVGAPADHLLGLEGVDGAVGPRFRKLTPQEIEDYLTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYU9</accession>
    <name>X0BYU9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979901">
        <property type="protein sequence ID" value="EXK75702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYU9"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_12_1"/>
    <dbReference type="OrthoDB" id="1577640at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="93" mass="10298" checksum="573D7BFC18F3FFDF" modified="2014-05-14" version="1">MSNPNDYTVGWICAITTEYVAAQEFLDEEHEGPEYVSPNDTNHYTLGKVGKHNVVIAVLPDNEYGKSSAASVARDMLHSFPNVRIGTNRNINC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ75</accession>
    <name>X0BZ75_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09276</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ75"/>
    <dbReference type="HOGENOM" id="CLU_2291824_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="101" mass="11800" checksum="C9D767D1B4754C64" modified="2014-05-14" version="1">MNIVAHSYDVRTSNSSALISYRGPRGRFMLDLKRKIQLKGLTRHYQPLQLKRYFGHKLCATEKSGTEFSYTTTESPSTKTDYSRGITDRFFRTWRLLKSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZD9</accession>
    <name>X0BZD9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Opsin-like protein carO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Carotenoid biosynthesis cluster protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_11838</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZD9"/>
    <dbReference type="eggNOG" id="ENOG502RWTP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054785_2_1_1"/>
    <dbReference type="OrthoDB" id="10261467at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15239">
        <property type="entry name" value="7tm_YRO2_fungal-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000160">
        <property type="entry name" value="Related to Opsin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018229">
        <property type="entry name" value="Rhodopsin_retinal_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043476">
        <property type="entry name" value="Yro2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF1">
        <property type="entry name" value="30 KDA HEAT SHOCK PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00950">
        <property type="entry name" value="BACTERIAL_OPSIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="9" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="294"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00069581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00078035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK83884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="307" mass="33989" checksum="BABC248C5D2AFAAB" modified="2014-05-14" version="1">MADHLYARKNDALNVNPDIVNGQRSDINITVRGSDWYWAVCAVMTVSTFAFLGLGMRKPRTDRIFHYITAGITMIASIAYFTMASNLGWTPIAVEFQRSDHRVAGIYREIFYARYIDWFLTTPLLLTDLLLTAGMPWPTVLWVILVDWVMIVTGLVGALVKSSYKWGYFAFGCAALAYIVYVLAWEARLHAKHVGPDVGRTFVMCGSLTAVVWILYPIAWGVCEGGNLIAPDSEAVFYGILDLIAKPVFGALLLWGHRNIDPARLGLRIRDIDERIFPDGPNNKATSGHGARNDTATASGANVNPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZT8</accession>
    <name>X0BZT8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979620">
        <property type="protein sequence ID" value="EXK76057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZT8"/>
    <dbReference type="HOGENOM" id="CLU_3111921_0_0_1"/>
    <dbReference type="OrthoDB" id="10269533at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="51" mass="6141" checksum="5D1BC757C4A4F4CF" modified="2014-05-14" version="1" fragment="single">MSTPWLRSLRLFKTEKTFIFGRLLIQEKLIAWLHKRHMTRALQRSQEGCAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0J8</accession>
    <name>X0C0J8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_11208</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0J8"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK84683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="525" mass="59742" checksum="05F59AC462562CEF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0N6</accession>
    <name>X0C0N6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_11255</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0N6"/>
    <dbReference type="eggNOG" id="ENOG502SHDE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007003_7_1_1"/>
    <dbReference type="OrthoDB" id="2154091at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14653">
        <property type="entry name" value="ZIP_Gal4p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK84733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="666" mass="75349" checksum="23C19E46355BFF8D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3R2</accession>
    <name>X0C3R2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3R2"/>
    <dbReference type="HOGENOM" id="CLU_000288_125_17_1"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205">
        <property type="entry name" value="NB-ARC AND TPR DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205:SF1">
        <property type="entry name" value="ZU5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="466" mass="52800" checksum="CD7F689AAB6DB345" modified="2014-05-14" version="1">MVGPRFNDPVYGSNVVTGISATGNAHQTFNFNQRFESRPFFLFPYQKNEDFVPRSEISSKIEELLPKNSDDFRSAALWGLGGSGKTQIALDFAYSRYSKKQCSVFWVHANSETTFAQDYGSIASVLGMKTQGPGSEFLQNVRHRIESLPRWLLVIDNADDLSLFGVGSTVRNTSKIMNYIPKGPNGTILWISRDEAIIGSLVGVRRGITVPRMTSDESKTLLESAMPQSISDDELDDVTLLLEALQFLPLAILQAGTYMQRTETSASQYLNDLKEEKKRWHTLKEPEFDRYRLHNSFNSILETWSPSIHRIHQENELAYKILHILAYVDKQTITERLVNAAAAHGETKQMRDMFESKKRQAIHRLKNFSFLIEHRLDDNERTYEIHKLVKDAVRYSLRNESILDGHANKPNKDSRRLGACIKRRIKNNGRIKGDPSEGESSFAGAAADIVASLYPRKAHLKTGEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4T5</accession>
    <name>X0C4T5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979376">
        <property type="protein sequence ID" value="EXK77767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4T5"/>
    <dbReference type="HOGENOM" id="CLU_510018_0_0_1"/>
    <dbReference type="OrthoDB" id="5106861at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="537" mass="60415" checksum="6015062F031EA898" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C560</accession>
    <name>X0C560_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Threonine synthase</fullName>
            <ecNumber evidence="5">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_10348</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-homoserine + H2O = L-threonine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.2.3.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:10841"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the threonine synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="5"/>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C560"/>
    <dbReference type="eggNOG" id="KOG2616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015170_1_0_1"/>
    <dbReference type="OrthoDB" id="5203861at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01560">
        <property type="entry name" value="Thr-synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000046">
        <property type="entry name" value="THR4p Threonine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1380.10:FF:000003">
        <property type="entry name" value="THR4p Threonine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="entry name" value="Threonine synthase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051166">
        <property type="entry name" value="Threonine_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690">
        <property type="entry name" value="THREONINE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690:SF1">
        <property type="entry name" value="THREONINE SYNTHASE-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24857">
        <property type="entry name" value="THR4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Threonine synthase N-terminal" evidence="14">
        <location>
            <begin position="13"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="13">
        <location>
            <begin position="96"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK85944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="539" mass="59861" checksum="6777032744C21CEB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C606</accession>
    <name>X0C606_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_09497</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C606"/>
    <dbReference type="eggNOG" id="KOG0201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007561_0_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000670">
        <property type="entry name" value="Serine/threonin protein kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="43"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="398"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="619"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="703"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="449"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="703"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK86633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="839" mass="92315" checksum="20714DBCA0020E85" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6B3</accession>
    <name>X0C6B3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein arginine N-methyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_07422</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6B3"/>
    <dbReference type="eggNOG" id="KOG1499">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017375_1_2_1"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.160.11:FF:000001">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000050">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="5">
        <location>
            <begin position="64"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="6">
        <location>
            <begin position="166"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK89965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="345" mass="39604" checksum="ACA6E0DFA84B0E2C" modified="2014-05-14" version="1">MSGDKMDVEIAEQKMNSMEHSEQHYFKSYDHHGIHEEMLKDEVRTRSYMNAIMQNKHIFKDKVVLDVGCGTAILSMFAAKAGAKHVIGVDMSTIIFKAREIVKVNGLSDKITLLQGKMEEVELPFPKVDIIISEWMGYFLLYESMLDTVLYARDTYLQKDGLIFPDKATIFFAGIEDGDYKEDKIEFWNDVYGFDYTPLKATALSEPLVDTVEVKAAVTEPTAVLTLDLYKCTTDDLAFQVPFKLSVTRDDFVHALVSWFDIDFTACHKPIRFSTGPHTKYTHWKQTVFYFEDVLTVQQGEQIALNLDVRPNSKNRRDLDIKISYELETEDANRASKGALEYRMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C729</accession>
    <name>X0C729_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C729"/>
    <dbReference type="HOGENOM" id="CLU_430823_0_0_1"/>
    <dbReference type="OrthoDB" id="4925544at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="673" mass="74887" checksum="91B5185989AC665B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8F5</accession>
    <name>X0C8F5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8F5"/>
    <dbReference type="eggNOG" id="KOG1968">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003721_0_0_1"/>
    <dbReference type="OrthoDB" id="9996895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF21">
        <property type="entry name" value="ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="565"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1083"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1147"/>
            <end position="1157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1157" mass="128419" checksum="3E6657DABCEA9A45" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8N0</accession>
    <name>X0C8N0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_08909</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8N0"/>
    <dbReference type="eggNOG" id="KOG0134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_6_2_1"/>
    <dbReference type="OrthoDB" id="1663137at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051799">
        <property type="entry name" value="NADH_flavin_oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656:SF2">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="5">
        <location>
            <begin position="18"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK87568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="374" mass="39742" checksum="CCA45A74F33C12D0" modified="2014-05-14" version="1">MAERLADKEGLPGGKQCLATYSEWAKGGWGLIISGNVHIDPAHPGAPGDFTVNRDVPREKTLAAWKSWASACSLNGTKSIVQINHPGRQAPFVKSLAPSPIPLDLGKGLFPWLVRSLVYGTPKEMTQADIDDVVTRFAEAAKLSVEAGFAGVEIHAAHGYLLAQFLSPLSNERTDDYGGSPLARAKIVVDVVKAVRKAVPAGACVGIKVNSTDHTDLGDFITQLKAIVDAGVDFVEVSGGSIEDPMFSTGLHTTVKASTKAREAFFIDFANAIRSELPDVPIMLTGGFRTRQGMEAAVKGGSCDLVGLARPSVIDPALPKKVLDTSIPEYGALAYAKRIEAWSWAKYTGIKAVGMGAETLWYTNQIGRLGAANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8S8</accession>
    <name>X0C8S8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine(10)-N(2))-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.214</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_09463</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM11 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.214" evidence="9"/>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8S8"/>
    <dbReference type="HOGENOM" id="CLU_029646_3_0_1"/>
    <dbReference type="OrthoDB" id="296065at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160102">
        <property type="term" value="F:tRNA (guanine(10)-N2)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016691">
        <property type="entry name" value="TRMT11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059073">
        <property type="entry name" value="TRMT11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370">
        <property type="entry name" value="RNA METHYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370:SF3">
        <property type="entry name" value="TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25904">
        <property type="entry name" value="Tmrp11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017259">
        <property type="entry name" value="tRNA_mtfrase_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51627">
        <property type="entry name" value="SAM_MT_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA (guanine(10)-N(2))-methyltransferase TRMT11 N-terminal" evidence="12">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="11">
        <location>
            <begin position="182"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK87219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="444" mass="50086" checksum="56B79C1209822D1D" modified="2014-05-14" version="1">MDFLIKFAQAHETFRVPEIEALALVEGLDMKIVDYSQDSPFCIVHLDSVESAKRLAKRSILIQSIHELWGKGSTLDVLHESVKTNTSHVWDSYLGKSFKFDVDPYQGTRSAKKRIELINSFRFLGWTGPVKMTNPDNLFTIFEMWPYNSVPLNIPDPTMMYLARHVGNSSRELLVKFDLKKRGYISTTSMDSELALVTANLALAAPGKLFYDPFVGTGSFPIACAHFGALAFGSDIDGRSIRGEGGNKSLKGNFDQYGIGSCLGDVFSADLTNTPIRRHLRTWDGIVCDPPYGVREGLRVLGLRDPEKTPWLIEQGKQHGMKPTYVPPKKPYSFLVMLDDILAFASETLVDEGRLSFWMPTANDEDQEIPVPSHPYMGVVSVCTQPFNKWSRRLITYRRLPDSQVSQEALEAYTNRQKLTLNGTSADELNPFRRGYFKKFEAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9H3</accession>
    <name>X0C9H3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658474">
        <property type="protein sequence ID" value="EXK79332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9H3"/>
    <dbReference type="eggNOG" id="ENOG502RJ3N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071337_0_0_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="243" mass="28325" checksum="B3A3BC3838CD79EC" modified="2014-05-14" version="1">MIEKMVEQISKYWPPGPPAMQQMESKDPDILQYYQQWGFDIYRTYYGPGSDEAWGKLLYALKHQTRLAFGHYDGREDADQRHVDILKDLFYLDARADKSLLDGLDVQGIRKFCRHENTDKDRVMSVSIHDYVLLADESTLKDVSGREFVVKAVSLDWKRGHRGWGWMRIPTGYLLDLWQLLMLNSMRTELAIDFDGPEEDLGDYVWPGDLALNNTGSYSEIRQFLKHYSGQSPRRSLECDKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBI5</accession>
    <name>X0CBI5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Immune-responsive protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08554</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpD family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBI5"/>
    <dbReference type="eggNOG" id="ENOG502QVEB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026574_1_1_1"/>
    <dbReference type="OrthoDB" id="10267976at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4100.10">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036148">
        <property type="entry name" value="MmgE/PrpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042183">
        <property type="entry name" value="MmgE/PrpD_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005656">
        <property type="entry name" value="MmgE_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045337">
        <property type="entry name" value="MmgE_PrpD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045336">
        <property type="entry name" value="MmgE_PrpD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943:SF8">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19305">
        <property type="entry name" value="MmgE_PrpD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03972">
        <property type="entry name" value="MmgE_PrpD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103378">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MmgE/PrpD N-terminal" evidence="2">
        <location>
            <begin position="14"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="MmgE/PrpD C-terminal" evidence="3">
        <location>
            <begin position="291"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="52867" checksum="60EEF40240A63BCC" modified="2014-05-14" version="1">MSEPKPKSSSPTVQLSQWISKLKLDDIPDRVCTRAKYLILDRLAYAFVGSHLPWSETAAQAILNLEPTQGDASLIGWEGRKVTALTAALLNGTFIQGFELDDWHSEAPLHSNSIILPALLAAAEQANAQASHFTTSGKDFLLATIAGYETGPRVGRSLWGTHVLSSGWHSGAVFGPAAAAASVSKLYGLDADTIEDAFGIACTQSCGLMSAQFESDVKRMHHGFAARNGLLAAVLAQGGYVGIKQVFEREYGGFLKQFSSGNGKQPQYRPQELTSELGIRWQTNGIVIKPYAAMAGTHPSNDCIRHLQEQNPDRMKRFDGIKKIDILLGEAAFHHGGWRAAKPLTATGAQMSNSFTAATQIVHGQVLMPQFTPDTLVDEDVWRLVDLTECKLHITDGDSIGCQEVGIRFEDGTVLHHSVPSAFGVEPPLSNDDIVAKWRQLTRDIVENEVVEKIEEIVLSLEEQDDLVTLFELIRQTSKNPLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBK1</accession>
    <name>X0CBK1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase M20 domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08392</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBK1"/>
    <dbReference type="eggNOG" id="ENOG502QQPD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031812_1_1_1"/>
    <dbReference type="OrthoDB" id="6119954at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05672">
        <property type="entry name" value="M20_ACY1L2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.360:FF:000004">
        <property type="entry name" value="Peptidase M20 domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017144">
        <property type="entry name" value="Xaa-Arg_dipeptidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF4">
        <property type="entry name" value="PEPTIDASE M20 DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037226">
        <property type="entry name" value="Amidohydrolase_ACY1L2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939265" description="Peptidase M20 domain-containing protein 2" evidence="3">
        <location>
            <begin position="27"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="4">
        <location>
            <begin position="217"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK88603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="450" mass="48299" checksum="292D1376A2326459" modified="2014-05-14" version="1">MVCLDHARGLAAFVFGLTLLAAPASSLQTTLEPRQKKNATSPYTDAVSDYVDSLDKELWSINKNIHDNPELGYKEFKAHKLLTSFMKKQKGWNVTDTVGGIDTAFMAVFDGSGDGPVVSFNAEYDALEGLGHACGHNLIATASLGGALATAEIMRKEKLGGKVILFGTPAEESLGGKVKMLEAGVFKDAKIDISLISHPSNGPDTPYMLAQSTDRVDVEYIGREAHAAAGPWEGINAQDALLLANSALSYMRQQMRTTDRVHGIIHSAGTRINVIPADASGSYQLRAANEEQLEELSDRVYNCFKAGALGTGAKMNFTTRPYGYANMNNNDGLAASYTRWFEELGGDLPDADVDKMREPGGSTDQGNISQDFPAISPMFQITFANGTVPKSGPHTAPFEVAAGSKPAFEKALMVAKGLAGVAVDVLTVDGLLDDIKDEFKKTKSPARRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCK0</accession>
    <name>X0CCK0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08362</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCK0"/>
    <dbReference type="eggNOG" id="ENOG502SH5J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006524_0_2_1"/>
    <dbReference type="OrthoDB" id="3365636at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR PBCR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="7"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK88564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="555" mass="61680" checksum="DB17E7F52BDEB7B2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDB6</accession>
    <name>X0CDB6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDB6"/>
    <dbReference type="eggNOG" id="ENOG502QS8H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_49_0_1"/>
    <dbReference type="OrthoDB" id="294702at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45763:SF46">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45763">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="47"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="319" mass="36391" checksum="20D5C6A18E03951A" modified="2014-05-14" version="1">MSVQAVRNRSTSSTRRLLTTSSQIHQTFHLSDGRTLGFAEFGNQDGKPVFYFHGYPSSRLEAQPIHEIAQRCGVRLIAIDRPGFGLSTFKPGYQILDWPTDVMEFAQAHQIPKFSVLGLSGGGPFALACAYALPKRAITSVGLFATAPHWAAGTKHVEYYRRVFKVWAEYSPSTLRAALYMLYLSLRWIVLSGPVSRRLSKWLEAQHKKEEAESEAPKPKSPSLEELVEMVLDEPFRQGADGAVHEMNLLTSKNWGFDLEKVQYDNIQIWHGKKDVNAPIQMIRYMAERIRGCELHEFEDETHYTMYKHFEPALRELVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEB0</accession>
    <name>X0CEB0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658432">
        <property type="protein sequence ID" value="EXK80972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEB0"/>
    <dbReference type="HOGENOM" id="CLU_2084919_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="117" mass="12913" checksum="B8D356D1D9FEFAF7" modified="2014-05-14" version="1">MIKGCLETSTRPTRLVDRYRLILTLASSALLLLAQASCATRRAQAIARRPLALRDGAFRADRRNALNESVTDWFLPVCANTPTAADARRDNSPLALHQTVLWRCHEAALGGNSLWSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF79</accession>
    <name>X0CF79_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF79"/>
    <dbReference type="eggNOG" id="ENOG502R8BV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021363_0_0_1"/>
    <dbReference type="OrthoDB" id="5244801at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="531" mass="58668" checksum="AA3D1BED47869D21" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIY9</accession>
    <name>X0CIY9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Regulator-nonsense transcripts 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_06681</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs. Also capable of unwinding double-stranded DNA and translocating on single-stranded DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIY9"/>
    <dbReference type="eggNOG" id="KOG1802">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001666_4_0_1"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21407">
        <property type="entry name" value="1B_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21400">
        <property type="entry name" value="ZBD_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.230:FF:000003">
        <property type="entry name" value="Regulator of nonsense transcripts 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000097">
        <property type="entry name" value="Regulator of nonsense transcripts 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040812">
        <property type="entry name" value="UPF1_1B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018999">
        <property type="entry name" value="UPF1_CH/ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18141">
        <property type="entry name" value="UPF1_1B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09416">
        <property type="entry name" value="UPF1_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51997">
        <property type="entry name" value="UPF1_CH_RICH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Upf1" evidence="17">
        <location>
            <begin position="87"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="C3H" evidence="15">
        <location>
            <begin position="95"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="CC/SHH/C" evidence="15">
        <location>
            <begin position="109"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="C4" evidence="15">
        <location>
            <begin position="155"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="899"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1049"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="899"/>
            <end position="915"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK91213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1083" mass="119464" checksum="26C1EFD54150088A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJU7</accession>
    <name>X0CJU7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fucose-specific lectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJU7"/>
    <dbReference type="eggNOG" id="ENOG502RJ2S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1475283_0_0_1"/>
    <dbReference type="OrthoDB" id="4652505at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.70">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89372">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20385" checksum="727C072DCEC45B97" modified="2014-05-14" version="1">MTSAEAFKELPRDIAAVDVKGMTYVFFVNSNHQLCYLLSPGPETDDYDPRVVKLTDGDLKVKCGSRQIAAAAWQGGNGQEIRIYCIAPEKGQCENKGYIQEVSFSSSTGWEHGLLGYKEEGRPYVDKDASLTACVHTWPDKTDIKVFASGKGENGRPKITMHQYSYGHKKWLGKVISNKVSDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CK09</accession>
    <name>X0CK09_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_04574</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CK09"/>
    <dbReference type="eggNOG" id="KOG1305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009020_1_0_1"/>
    <dbReference type="OrthoDB" id="438545at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061459">
        <property type="term" value="F:L-arginine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005290">
        <property type="term" value="F:L-histidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015189">
        <property type="term" value="F:L-lysine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015194">
        <property type="term" value="F:L-serine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005302">
        <property type="term" value="F:L-tyrosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF678">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="11">
        <location>
            <begin position="37"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="434"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK94526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="526" mass="56731" checksum="39D25D1CB577097C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLI7</accession>
    <name>X0CLI7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03913</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLI7"/>
    <dbReference type="eggNOG" id="ENOG502QQMM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003021_1_0_1"/>
    <dbReference type="OrthoDB" id="207120at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11887">
        <property type="entry name" value="SH3_Bbc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057402">
        <property type="entry name" value="AIM3_BBC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035552">
        <property type="entry name" value="Mti1_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050670">
        <property type="entry name" value="STAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929">
        <property type="entry name" value="JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929:SF7">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25459">
        <property type="entry name" value="AIM3_BBC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="2"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="56"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="407"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="449"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="466"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="546"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="561"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="598"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="649"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="667"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="693"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="708"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="754"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="777"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="819"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="862"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK95300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1226" mass="132259" checksum="0E2EC9AE0CFB1C82" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMM6</accession>
    <name>X0CMM6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMM6"/>
    <dbReference type="HOGENOM" id="CLU_2236729_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="105" mass="11952" checksum="AFF02523A67E21EE" modified="2014-05-14" version="1">MLMRFMPTGTQGNDSRNEKNKQSLAPHIAIPKWYQVARGMVSSFIPRPCTPIPLLLGEAVCNALKRQQITEKTPTAIQNLKHSKHNTHDRKRNGETKHVRAMHES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMV0</accession>
    <name>X0CMV0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sister chromatid cohesion protein DCC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMV0"/>
    <dbReference type="eggNOG" id="ENOG502SA0V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116847_0_0_1"/>
    <dbReference type="OrthoDB" id="5199543at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019128">
        <property type="entry name" value="Dcc1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09724">
        <property type="entry name" value="Dcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="13854" checksum="6F5A1BB1411252A3" modified="2014-05-14" version="1">MSSQSGGITVQYNPSSTNYRLIELPPDLLSLLESDDAPVLTMESSDSSAVIKTPTKTYALRQKNTSNALMLLSPTPLPASSDGPLEQGVSIISTIKETVELDTVPDVSAGTTKGFGGGKGKWHERFGRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMY0</accession>
    <name>X0CMY0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">D-arabinitol 2-dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMY0"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OrthoDB" id="5325318at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK83902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="28990" checksum="17097470091B5F7C" modified="2014-05-14" version="1">MTTFNPRGLGDVKVTDRFDLTGKNFLITGGGGGIGFACAKAIAQLGGGVAVIDTAPEPVEEFKSLSDRYGAKTFYTRGDVTKQDSLEKAFAECVDAMGGQLHGALTAAGIVMDTPLLDADWEVTQRVLNVNVMGTYWTIKLLAQHLVETKSPGSIVAIASINAQSLYVPVQPKSAYNASKAAIKGLMGPLAGELGQYGIRVNCISPGAIQTPLLARLQGEKRAILDWYENGAPLQRLGVPEDLTPMVCYLLSDAAAFTTGADMLVTGGLHAGSALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN02</accession>
    <name>X0CN02_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN02"/>
    <dbReference type="eggNOG" id="ENOG502S1QQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070836_0_0_1"/>
    <dbReference type="OrthoDB" id="58379at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="268" mass="30604" checksum="A2A6ED3931A18D2B" modified="2014-05-14" version="1">MSEKTKSAFFDYTEASSAAPPPFSQAVSNAGPSTFQSRFASITRHGLDRIRLVNFSEAEIAAVHEIVRTYWDRGIDKVYPQEASREFKLGGYAWGYDPNGNEQAMMLTLRILEGMHNLGWVIYSPIEVTKRVSTKDALIFRKVNHIPPPCEWINVSFHGGDKLKILNFPPSDLVNDIMATFMIDIQRHEVTPDRAKIKFKGYPWRPLESDGAETQLKLLALLEILERHGFTLYARTSARFTDETSESNVLVFQRRRDWVAGKSLYDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNQ3</accession>
    <name>X0CNQ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNQ3"/>
    <dbReference type="HOGENOM" id="CLU_2250267_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="104" mass="11924" checksum="9B35DBE647FCA641" modified="2014-05-14" version="1">MLRDKRHLGRARRRSRIRGWSVLSLRCVATRQNLKKFLSFPHIGKTLQTAQYAQLTTRPPRAVHHLLILLHLCAILLLPPPPSMFQVVNRGERQGAMASSDRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPT4</accession>
    <name>X0CPT4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPT4"/>
    <dbReference type="HOGENOM" id="CLU_3068701_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="53" mass="6083" checksum="79EC9BAC3AC8A3B1" modified="2014-05-14" version="1">MRDSEPSNQAAHMPTLQPQKCMGALHGLCQLDVARRDETTSVRIRLRMRKKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS11</accession>
    <name>X0CS11_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit WBP1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_10654</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DDOST 48 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS11"/>
    <dbReference type="eggNOG" id="KOG2754">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031804_1_0_1"/>
    <dbReference type="OrthoDB" id="29105at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005013">
        <property type="entry name" value="DDOST_48_kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055459">
        <property type="entry name" value="OST48_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055457">
        <property type="entry name" value="OST48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23358">
        <property type="entry name" value="OST48_MD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03345">
        <property type="entry name" value="OST48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152147" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1" evidence="8">
        <location>
            <begin position="19"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 N-terminal" evidence="9">
        <location>
            <begin position="25"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 middle" evidence="10">
        <location>
            <begin position="301"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK85287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="458" mass="50990" checksum="8E7A1F068C6BBA84" modified="2014-05-14" version="1">MRSLLSLVVFLFAALVSAVSTTGNRLLVILDTPKDKEAYTTFFRDLSERGYDITYETPKSDDLTLFKYGERSYDHLVFLPTKIKGLGPNLTPNAIVDFINAGGNILLTMSATHKVPVTLVSVLDQLDVTIPAERNGKVVDHFTYDAVSAAETHDTLVLDAPRNVRPGLKDYFEIPGAFISVPHAIGHTLGSGPLLTPVLRAPPTAYSYNPKEQADTVEPDELFAAGKQLALVSVFQARNSARVTVIGAAEMLQDKAFDTKVTRQGGKAIFPANKEFVTNLAGWTFQELGVLRVNKIEHHLKGDNETNPELYRIKNDVTYSISVSEYAWNDWQPFRLPEGDHLQLEFSMLSPFHRISLKPVHVGEQETVYGTDFVLPDQHGIFNFMVNYKRPFLTNLEEKRTVSVRHMAHDEYPRSYVINGAWPGLTGISATIVGFLSFCIVWMYSQPVKPAAGAKKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTK3</accession>
    <name>X0CTK3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-rRNA processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_02677</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTK3"/>
    <dbReference type="eggNOG" id="ENOG502QZVV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006918_0_0_1"/>
    <dbReference type="OrthoDB" id="5596576at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059065">
        <property type="entry name" value="Ig_Tag1-like_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059066">
        <property type="entry name" value="Ig_Tag1-like_5th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055011">
        <property type="entry name" value="Tag1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF3">
        <property type="entry name" value="PRE-RRNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26174">
        <property type="entry name" value="LEA-2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26150">
        <property type="entry name" value="LEA-2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26153">
        <property type="entry name" value="LEA-2L_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22786">
        <property type="entry name" value="Tag1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Tag1 C-terminal" evidence="3">
        <location>
            <begin position="465"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Tag1-like fourth Ig-like" evidence="4">
        <location>
            <begin position="589"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="Tag1-like fifth Ig-like" evidence="5">
        <location>
            <begin position="730"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF26153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK97501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="854" mass="93380" checksum="86CCD2C2C5534D9E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUC0</accession>
    <name>X0CUC0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUC0"/>
    <dbReference type="eggNOG" id="ENOG502R6HT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_628578_0_0_1"/>
    <dbReference type="OrthoDB" id="5095558at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="440" mass="49246" checksum="E9AC7487D93A619F" modified="2014-05-14" version="1">MEIPGIDFMKSLEDLFSEAGANGRDAKTEFVHLRSSLIDFITTVSGGGLTAAKARAKYNLKFTDGTEPETHIAFFPSNHNITEKRPQLDAATTAKEFIEILGALFSEQKSRSRRKRKPNKKRSNTTPPESSMNNAQKRLEADAANKTLSTTDDSPRKRIKLNTSKNKSDVSEPAVFSTAHQSKDNTPTEFPSTENMVNDDGNSVLVPMDIDSGAASSHDKGEEMNGEQTPADGQKHHGSALEGPSQDRKDTHMNDADIETLPAYCRSDILEVAAAAESIEENQWKDFKPKLLEMLGQMHQEPTPEQHEKALKRLSIAIAQTEQERSLIPVEAWKKYEEKLTDETKKGLFDCLWSRRLFKVGKIIYLQEEEVAMESQCWERLRAAARICAILIEMTAKPEEQDNQNDTDLWLIEKLGDISFLEKLFACKERLGAIKGTGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUJ9</accession>
    <name>X0CUJ9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUJ9"/>
    <dbReference type="eggNOG" id="ENOG502SWUH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023048_1_0_1"/>
    <dbReference type="OrthoDB" id="5427699at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="411"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="599"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="198"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="337"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="441"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK98130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="670" mass="71575" checksum="821B7F764CD85C39" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV07</accession>
    <name>X0CV07_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_04675</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV07"/>
    <dbReference type="HOGENOM" id="CLU_1073782_0_0_1"/>
    <dbReference type="OrthoDB" id="5105709at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="107"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK94679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="300" mass="33085" checksum="36D68A6D122CF3D7" modified="2014-05-14" version="1">MAKDTSGNINTIITRMQALSTKTQTLDRGSKTGPHLFTDFMENTDEEDEDDEDVEGFDEDNIVAYLNTLHGCIIAKHVAPHIGYIPGLKPGNILFEHRRQAVGAAMQSPAGPFKVMILGGPLGLGKTLVALAVAALSWKPGDISSLIVAPLSCSCYLPSRRIRFPFRPAEIPGRDYILFISYCGGEPCRKVPGCHQRLQCGAGDPRPRETELFLRSGSLGSEPWKPIRKCMILDEAHVIKNRNTRKFAAVTALREQFEGCLTLTGTPLDNTWEDGYALLSLLKGHPITSFKIFQKIFKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVQ6</accession>
    <name>X0CVQ6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">ATP synthase subunit d, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_01430</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ATPase d subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVQ6"/>
    <dbReference type="eggNOG" id="KOG3366">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080463_0_0_1"/>
    <dbReference type="OrthoDB" id="35799at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008689">
        <property type="entry name" value="ATP_synth_F0_dsu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036228">
        <property type="entry name" value="ATP_synth_F0_dsu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12700">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05873">
        <property type="entry name" value="Mt_ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005514">
        <property type="entry name" value="ATPase_F0_D_mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161065">
        <property type="entry name" value="ATP synthase D chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0138">CF(0)</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK98560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="173" mass="19423" checksum="5F24AAC8C991B0C8" modified="2014-05-14" version="1">MATRSAALKLDWTKVTSSLGLRGQTVASLQAFKKRNEDVRRKVQQLQEQPTTVDFSQYRSVLKNQAIIDEIEKRFSAFKPVTYDVSRQLKAIDAFEAEAVKNAEATKEAVDLELKDLAATLKNIEEARPFEELTVDEVAAAEKSIDEKTAQLVSKGRWMVPGYKEKFGDLAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVZ8</accession>
    <name>X0CVZ8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Beta-glucosidase cel3A</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Beta-D-glucoside glucohydrolase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Beta-D-glucoside glucohydrolase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Cellobiase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="22">Cellobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Gentiobiase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Gentiobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Probable beta-glucosidase G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">FOQG_04046</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVZ8"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_2_3_1"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000757">
        <property type="entry name" value="Beta-glucosidase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000003">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF12">
        <property type="entry name" value="BETA-GLUCOSIDASE G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 23" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="23">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937261" description="Beta-glucosidase cel3A" evidence="23">
        <location>
            <begin position="20"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="24">
        <location>
            <begin position="726"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00039579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00041276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00070030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00078013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00083231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00083611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="EXK95478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="811" mass="88615" checksum="C1CD4E50A61D239C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWN8</accession>
    <name>X0CWN8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWN8"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10044938at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052600">
        <property type="entry name" value="Nuc_rcpt_coact/corep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23295:SF6">
        <property type="entry name" value="NEOSIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23295">
        <property type="entry name" value="NUCLEAR RECEPTOR COACTIVATOR 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="415"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="480"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="704"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="803"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="177"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="530"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="721"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="737"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="815"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK95678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="861" mass="91816" checksum="33B66A7609722893" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWY8</accession>
    <name>X0CWY8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ethanolamine utilization protein (EutQ)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWY8"/>
    <dbReference type="eggNOG" id="ENOG502S3HA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141740_0_0_1"/>
    <dbReference type="OrthoDB" id="4985585at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02228">
        <property type="entry name" value="cupin_EutQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010424">
        <property type="entry name" value="EutQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36169:SF1">
        <property type="entry name" value="ACETATE KINASE EUTQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36169">
        <property type="entry name" value="ETHANOLAMINE UTILIZATION PROTEIN EUTQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06249">
        <property type="entry name" value="EutQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="17075" checksum="5A6CCFBE458C6045" modified="2014-05-14" version="1">MKGTLPRLSVSSIKQSTSVSNIPSLHLNKPLKVNLQKTIKMASFKHFAQAQSKFEIPPLSGGNTFIGDIHSTPEGAEKPLAMGLFRVNKGEPLTYTYKYDECKIILEGNFVIEDSTGQKVEAKAGDVFYIPNGATLTFSSPDTGLAFYTGARKMGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXG1</accession>
    <name>X0CXG1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_04117</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase gamma subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXG1"/>
    <dbReference type="eggNOG" id="KOG1764">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021740_1_1_1"/>
    <dbReference type="OrthoDB" id="286637at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04618">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04641">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF35">
        <property type="entry name" value="LD22662P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="220"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="301"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="377"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="451"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="513" mass="55582" checksum="75B9D5B164C2F2AE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXT5</accession>
    <name>X0CXT5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01864</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXT5"/>
    <dbReference type="eggNOG" id="KOG2690">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035242_0_0_1"/>
    <dbReference type="OrthoDB" id="73788at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051494">
        <property type="entry name" value="BSD_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019:SF5">
        <property type="entry name" value="BSD DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="2">
        <location>
            <begin position="233"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="437" mass="47939" checksum="FD06FE9D8C6CCFFE" modified="2014-05-14" version="1">MDLAYDHITEDGYAKKTEEPRSPQPQSTLNEDLQDAYKAFSNSPWGARIGGFFGNVVKQGESVYTQASKELAEVGEDASKGLTGLRSTILSHTRNLSLNTVTGGESSRDGENDQATTPRASQDGSSEAKQSENTLARLRAEAAKRLKDLQKAEDAADEALIKFGGNVRNFLRDAVSIAPPQESDQSGTVLFESKDAQGKRVIHTSRFDAQLHVIHTSTESFTKDPNSADYAAWSKDFDADKKTPEINDDLQKFPDLRATMERLVPDQVPYVDFWKRYYFLRHGIETAEARRRDLLKAASAEDDVAWSDDDSDEDDSDASDDTSTPAAKTKVETKVEPKDEPKTTPATPSTTATTATTATTTQPAKTLLKPTEPRKSNDEKSQADSEASYDVVGAASGKTTQTPNSPKDPKDAKKKEESSDEEDDSDEDDSDSDEDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXY0</accession>
    <name>X0CXY0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ras guanine nucleotide exchange factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_03279</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXY0"/>
    <dbReference type="eggNOG" id="KOG2378">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005431_1_0_1"/>
    <dbReference type="OrthoDB" id="28357at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF348">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR RASGEF, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="307"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="534"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="174"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="223"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK96143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="789" mass="88856" checksum="782AD666AB9DB357" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY55</accession>
    <name>X0CY55_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY55"/>
    <dbReference type="eggNOG" id="ENOG502SA5E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086075_1_0_1"/>
    <dbReference type="OrthoDB" id="5335351at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024526">
        <property type="entry name" value="DUF3807"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40642">
        <property type="entry name" value="YALI0F31295P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40642:SF1">
        <property type="entry name" value="YALI0F31295P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12720">
        <property type="entry name" value="DUF3807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="192" mass="21648" checksum="200CF55FFF95C491" modified="2014-05-14" version="1">MPDLALKKNQDMPQSNNGSTTNAHVIPNISPDDLVAFHESHFSHTAVAAFGSEFIDSPPQDQTQDDAVDDSWEEEDDNLGYYPDGVKRTLTDAQIEIFRHSELETLRKEKERAKQLGSKETAPSSEAMDLSDDTPTSMQTKNMSSSLPASFQSNKKRKKKKGLQRPRPEPKPDLRKRTWDIVDKGLDSLEYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYT9</accession>
    <name>X0CYT9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYT9"/>
    <dbReference type="HOGENOM" id="CLU_3191324_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="46" mass="5628" checksum="9FC02B19B64B5E0D" modified="2014-05-14" version="1">MKSLANLETEEVKRRPRMHQHRSLAVDKKDTLRILGHRRLWTDQLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYV2</accession>
    <name>X0CYV2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GrpB domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYV2"/>
    <dbReference type="eggNOG" id="ENOG502SEGQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086407_1_0_1"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007344">
        <property type="entry name" value="GrpB/CoaE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34822">
        <property type="entry name" value="GRPB DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G01530)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34822:SF1">
        <property type="entry name" value="GRPB FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04229">
        <property type="entry name" value="GrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="23048" checksum="01D5B5320E34EFBF" modified="2014-05-14" version="1">MTPTIEELLKEYDFDPSLIDRIAFRKHKQPIAIVEPDPKWPEHFARAKARIESAIGDTAVSINHVGSTSIPGLPAKAVIDIDLTVKDINDEASYANALENAGFHFLVREPEWHGHRFFCDYEPVPTNLHVWGPGCPEVVRHKIFADWLRKNEDDRKAYENIKREAAKASAENGEDVMEYNNRKQNVIREILQRAFKDLGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ72</accession>
    <name>X0CZ72_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ72"/>
    <dbReference type="HOGENOM" id="CLU_155368_0_0_1"/>
    <dbReference type="OrthoDB" id="5426988at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="15131" checksum="518ADFB200992FB7" modified="2014-05-14" version="1">MPLLNYTVLSTRTALENMTTLQDHRFQDPEFPEQNPSSKIVILNGFPGTGKLTILQNLKKFLPGGTTFLLDNHLLIDPVAAIIPDRSNRHHELRRNILILLEKVTLRSIGSIYVAKWIFLSTGSVLLSDGGAARPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0T9</accession>
    <name>X0D0T9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rhomboid-type serine protease</fullName>
            <ecNumber evidence="10">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_00373</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serine protease involved in intramembrane proteolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="10"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0T9"/>
    <dbReference type="eggNOG" id="KOG2290">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2146116at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002610">
        <property type="entry name" value="Peptidase_S54_rhomboid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936:SF69">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936">
        <property type="entry name" value="RHOMBOID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="426"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="514"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="12">
        <location>
            <begin position="328"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="150"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXL00042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="572" mass="62729" checksum="61F5352CF5483008" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>X0D140</accession>
    <name>X0D140_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial aspartate-glutamate transporter AGC1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Aspartate-glutamate carrier 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_00424</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Calcium-dependent mitochondrial aspartate and glutamate carrier. Transport of glutamate in mitochondria is required for mitochondrial transamination reactions and ornithine synthesis. Plays also a role in malate-aspartate NADH shuttle, which is critical for growth on acetate and fatty acids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer (via N-terminus).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D140"/>
    <dbReference type="eggNOG" id="KOG0751">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2161at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015183">
        <property type="term" value="F:L-aspartate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043490">
        <property type="term" value="P:malate-aspartate shuttle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000004">
        <property type="entry name" value="Calcium-binding mitochondrial carrier protein Aralar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000552">
        <property type="entry name" value="Probable mitochondrial carrier protein ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="100"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="172"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="340"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="438"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="536"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00059916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00082232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXL00127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="695" mass="76785" checksum="98417EBB0ACCACE1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4F6</accession>
    <name>X0D4F6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper-fist domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_01368</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4F6"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006878">
        <property type="term" value="P:intracellular copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.430.10">
        <property type="entry name" value="Copper fist DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051763">
        <property type="entry name" value="Copper_Homeo_Regul"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001083">
        <property type="entry name" value="Cu_fist_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036395">
        <property type="entry name" value="Cu_fist_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00649">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01090">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00412">
        <property type="entry name" value="Cu_FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57879">
        <property type="entry name" value="Zinc domain conserved in yeast copper-regulated transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50073">
        <property type="entry name" value="COPPER_FIST_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Copper-fist" evidence="9">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="146"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK98453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="473" mass="51171" checksum="85535E77AA1AF681" modified="2014-05-14" version="1">MIIDGEKYACEACVRGHRVSNCQHSGKSRLKTEACYGLSVPVITPGWMHFQYSSMDMSPSLALFPVTDHNPSIDRPLQHINKKGRPVSQCAHCRAMRKSRSAHVKCDCGEKTSKCAHLQPAVEGHTETCCCNHGGHCSCSHKNEPALDTVPESDSERESLTLSISGRPKPPGRRRRANTVHSDGVLTFDQHGNHKPAHRSNRVSQKCGPYQLNRVNSAHSTGSLGADSMLQKSTREPPSSRARAATNRERRVKSETASPLMSGASSFQNLNGNLPPLDLSGIEYPPYMANSTFDLFGSGFNSETDAPMYSAGLSAASVDWSHYDLSEMKGESFTPSSYSQAGTQSFNGLFDFGSGSEHLPHLANTTSTSGEVSEVEDFLPGGDGDYDGLEGFSRADSFIRQNGNVMANSTDLTTIDYDSFYKGADSGPMAGAGLSMVEDDPAFWMPNYNEGITTMDESPDPLGPASVPSFWGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5F8</accession>
    <name>X0D5F8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_07366</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5F8"/>
    <dbReference type="OrthoDB" id="2020720at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070990">
        <property type="term" value="F:snRNP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000047">
        <property type="entry name" value="Small nuclear ribonucleoprotein SmB, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="8"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="98"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK89882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="229" mass="23636" checksum="821CF4532DBAA995" modified="2014-05-14" version="1">MLRLCDRSTKLTRTEQINWRMRVTLNDGRAMTGQMLAFDKHMNLVLADTEEFRRVKRKQNKPSAPGASGSATQTIESEEKRTLGLTIVRGAHIISLSVESPPPADPSARLGKSAPGGIPSALAAGPGVARPAGRGAAPPSLAGPAAGVGGAPPPGFPGFPGAPGFPGRGGEFKQSRYPRRVSNGLQAPPPGFPGNFPPPAGFPGGAQFPPPGFNPGGPPPPGFQPPPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6E6</accession>
    <name>X0D6E6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01769</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6E6"/>
    <dbReference type="eggNOG" id="KOG2655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021805_1_0_1"/>
    <dbReference type="OrthoDB" id="5337438at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001827">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="3">
        <location>
            <begin position="151"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="415"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="432"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK99138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="522" mass="58716" checksum="70D1BDA428233602" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8I5</accession>
    <name>X0D8I5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Periodic tryptophan protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_00258</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat PWP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8I5"/>
    <dbReference type="eggNOG" id="KOG0291">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010458_0_0_1"/>
    <dbReference type="OrthoDB" id="3142434at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000219">
        <property type="entry name" value="Periodic tryptophan protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000470">
        <property type="entry name" value="Periodic tryptophan protein 2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001292">
        <property type="entry name" value="Periodic tryptophan protein 2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027145">
        <property type="entry name" value="PWP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="147"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="191"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="341"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="383"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="469"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="6">
        <location>
            <begin position="745"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="640"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="664"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK99873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="894" mass="99172" checksum="E4A6899E050F12A9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0DA11</accession>
    <name>X0DA11_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Succinate dehydrogenase cytochrome B subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_06207</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DA11"/>
    <dbReference type="eggNOG" id="KOG0449">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094691_0_1_1"/>
    <dbReference type="OrthoDB" id="588261at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03499">
        <property type="entry name" value="SQR_TypeC_SdhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018495">
        <property type="entry name" value="Succ_DH_cyt_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02970">
        <property type="entry name" value="succ_dehyd_cytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978:SF5">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01001">
        <property type="entry name" value="SDH_CYT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK91427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20551" checksum="3B9AF94BEA1E385B" modified="2014-05-14" version="1">MSVQRIGLGTMRGAGRPGVVFNQNVSRLAFIRLLSQQTRDHPSIVHMNQKEGHDILVKQRLNRPVTPNLTIYKVGQVWFSASAWTRITGLAVGGTAYLTLCAHAVAPYLGMGFDSAALVSAFGALPFAAKAAIKFGLLGFPFTYHFINGIRHLVFDLGFGYKKAQFKKSEAATWILSILGGLVLAFWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0DC02</accession>
    <name>X0DC02_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DC02"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="142" mass="15963" checksum="DC92CC916C62D77C" modified="2014-05-14" version="1">MAPFSLQICPIIRDLIFTPRISLLLPERITSNLPLTCRYCKSSTYLSLRNLSLLTCHRRSRATPDRRSQTENVQQLSVSTYRISKTHIGCTGTHTRVQDRDLQLFVVKPTIRFYGGGALLIVVTSSLRLTSDGGNTNVPLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0DC35</accession>
    <name>X0DC35_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ras modification protein ERF4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_00962</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Interacts with ERF2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DC35"/>
    <dbReference type="eggNOG" id="ENOG502S30T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018540_1_0_1"/>
    <dbReference type="OrthoDB" id="5377273at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031211">
        <property type="term" value="C:endoplasmic reticulum palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019383">
        <property type="entry name" value="Golgin_A_7/ERF4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051371">
        <property type="entry name" value="Ras_palmitoyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13254">
        <property type="entry name" value="GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13254:SF0">
        <property type="entry name" value="GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10256">
        <property type="entry name" value="Erf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Golgin subfamily A member 7/ERF4" evidence="8">
        <location>
            <begin position="456"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="298"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="585"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="592"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXL01104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="613" mass="66837" checksum="93838C293521BBFE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0DJA8</accession>
    <name>X0DJA8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CHY-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_04539</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DJA8"/>
    <dbReference type="eggNOG" id="KOG1940">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012592_0_0_1"/>
    <dbReference type="OrthoDB" id="10253329at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="6">
        <location>
            <begin position="571"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="164"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="323"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="654"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="344"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="655"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK94487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="684" mass="76793" checksum="E4EF38F9EA44A2C2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0DKN6</accession>
    <name>X0DKN6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar complex-associated protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_03700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DKN6"/>
    <dbReference type="eggNOG" id="KOG2153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012441_3_0_1"/>
    <dbReference type="OrthoDB" id="10263597at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011501">
        <property type="entry name" value="Noc3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07540">
        <property type="entry name" value="NOC3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028977">
        <property type="entry name" value="Nucleolar_complex_p3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nucleolar complex-associated protein 3 N-terminal" evidence="8">
        <location>
            <begin position="123"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="CCAAT-binding factor" evidence="7">
        <location>
            <begin position="476"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="336"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="75"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR028977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK94942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="665" mass="75269" checksum="FA01E1DBB9D28ACE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0DMB3</accession>
    <name>X0DMB3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DMB3"/>
    <dbReference type="eggNOG" id="ENOG502SB4Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_631669_0_0_1"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="460" mass="52480" checksum="3B6BDA1379FDEC68" modified="2014-05-14" version="1">MEAKHTVSSIITRLPIEIILLIVESLVPQNDATRPILPASHPITITLLSLTRVSKAIYPTACKLIWQNCLYLDTKSKLRKFRRYISKKSPITGRLPCDAYGSARLYLNPLRYKFDTASTYDTISPSACRASRRSGRINNDSDSDMSGDFSDDLSDGSQTRRNRAAPKASRSESAEDDGYPEHSRHDCAGYPMQDLRTIYILEDVLITLAPVLKTLIVDMPLRDIDPWEDVIILKSLRQGFEALVNVEELISIKDELYLGESAIGQYQVFTKWPKLRRLCLYNVMMEEQLWKDMASCPQLESAVFIRPDPSDDDLSDDDIKGEWARAWATANPRDTKRDGLVYEGPKMTIAFCNWPPYLPDFNSMIPHWQEVDPDNKISVLNVATHARYDRKARKRGPIASCQDWVRDHSLLGTIWSEVERKGQPVTPPIVFEEGQVEEDDDEWVDDDDGADWTDDDDDSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DNY3</accession>
    <name>X0DNY3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DNY3"/>
    <dbReference type="HOGENOM" id="CLU_3406403_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="30" mass="3500" checksum="950EEE97383D356D" modified="2014-05-14" version="1">MAQDVSWMWEAVRKAITERPISVENRHVGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0DUF3</accession>
    <name>X0DUF3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02897</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DUF3"/>
    <dbReference type="eggNOG" id="ENOG502QQP3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030042_0_0_1"/>
    <dbReference type="OrthoDB" id="18786at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019465">
        <property type="entry name" value="Cog5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048485">
        <property type="entry name" value="COG5_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049176">
        <property type="entry name" value="COG5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228:SF3">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20649">
        <property type="entry name" value="COG5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10392">
        <property type="entry name" value="COG5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 N-terminal" evidence="6">
        <location>
            <begin position="17"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK97862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="439" mass="48460" checksum="5E81F83F627B1854" modified="2014-05-14" version="1">MAEDIIADEEPSYIDYETFLDPDFSPASFANTLVVSTNNPNDTPLDLSTPLSRVLFDAQEIDSHIDVLTTRSAVPLLNYTQEQTQASKNIVGELDGQIQSLNDSYRQLEKEVIDKHAEADEVRLVALRLWETLKLGRSVGRCLQLGRQLEVQHSELDSGTGKEDHRALVRCAYTILSLREVLDRKAPGEEGFGLNRVDAVKSLQDTVITPIDRSVRERAERSIREFSVQPTSTFAQVEEIKARTASALTALYLLSPTTGFKPDKWVPRLLLQSLETYIRSALQASITALSRSLGQLPTLDKALADVMAKCQNVVSLEAVLETIKPPAHPLLPTSSQPTQSSLLQFLLAHLETGSLASFFWRTMASSLATRVQDIMNRGGVVARTLRTNKNTVGDAIRQAVVKGSQLHSALTGSKARTKTEVNWDREVAVMVGSVVNNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0DWR8</accession>
    <name>X0DWR8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA(Phe) 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4)]-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.282</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_01479</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36635"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="Rhea" id="RHEA-COMP:10379"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73543"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.1.1.282"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TYW3 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.282" evidence="2"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DWR8"/>
    <dbReference type="eggNOG" id="KOG1228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047426_0_1_1"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1960.10">
        <property type="entry name" value="tRNA wybutosine-synthesizing-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003827">
        <property type="entry name" value="tRNA_yW-synthesising"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036602">
        <property type="entry name" value="tRNA_yW-synthesising-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48418">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48418:SF1">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02676">
        <property type="entry name" value="TYW3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111278">
        <property type="entry name" value="SSo0622-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA wybutosine-synthesizing protein" evidence="10">
        <location>
            <begin position="13"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="252"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="265"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK98627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="310" mass="34239" checksum="58EE58B349E8305E" modified="2014-05-14" version="1">MQELASSPPAFVERKRKILEQLAIPDTEYTDASPKGSIDEGIRDLIDEINQQSGFVTTSSCAGRVSVFLEGRRVADTEGEDEQVAGVGGKGAGGAWLFVSHDPVPDKSGSTDWSSLFGLQKSTEAQETTGEPKERRLVHFKYEAMILHVLTASPEHAQLLLRCGLQAGFRESGALNIIPNGKDAATPMVAIRTMGLAFESLIGQQVDGHRQRIVSPEYLQTLVQIANERFIENKKRIERFQNAFRDAISAPVPRLNPEGQEWEDAAARRERKRAEGLRKKAELKAKQETEPESDRAKSGKEEDAGLLFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0DXN8</accession>
    <name>X0DXN8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIE subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_01653</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TFIIE beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DXN8"/>
    <dbReference type="eggNOG" id="KOG3095">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056580_0_1_1"/>
    <dbReference type="OrthoDB" id="5323195at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005673">
        <property type="term" value="C:transcription factor TFIIE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001097">
        <property type="term" value="F:TFIIH-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07977">
        <property type="entry name" value="TFIIE_beta_winged_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054600">
        <property type="entry name" value="TFA2_E-tether"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040501">
        <property type="entry name" value="TFA2_Winged_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016656">
        <property type="entry name" value="TFIIE-bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003166">
        <property type="entry name" value="TFIIE_bsu_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22254">
        <property type="entry name" value="TFA2_E-tether"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18121">
        <property type="entry name" value="TFA2_Winged_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02186">
        <property type="entry name" value="TFIIE_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016398">
        <property type="entry name" value="TFIIE-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51351">
        <property type="entry name" value="TFIIE_BETA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIE beta" evidence="9">
        <location>
            <begin position="73"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="250"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK98932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="304" mass="33860" checksum="868963DB46DC7AC8" modified="2014-05-14" version="1">MSSYLERQANAFKGTLSAAATKISNPSTNKASSLAVPSLAPPSPSPSAASDPNTPTAKRKRDAGPEVPYSQPQLTGYGAGVKTQMTYAVDYLKKKGDAKTITDIIDHLSLRNFDDEHKRQLAEGLRGHPRVEWKPDANLSEQTWKTGTYVHRPIIPGVKDATSLLAHLQAKTDASGVSVKDLKDGWPDCEDTISALEREHRILVVRTKKDNIPRYVWPNDPSLHHKVQPEFQSMWQRVQLPPLEEMHRKLTSVGQKPTSEDPRKAKDGQANKPKAQKRRKGNRIGKATNVHMAHLMQDYSGMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2P8</accession>
    <name>X0B2P8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979519">
        <property type="protein sequence ID" value="EXK76395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2P8"/>
    <dbReference type="HOGENOM" id="CLU_3087315_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="52" mass="6099" checksum="6D2FBFC9672E5BFB" modified="2014-05-14" version="1">MLIQKPRNPQNHTLRLQGHIRPPIQLIVSQQPRLPRMSLLELLSQQPQNQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0B616</accession>
    <name>X0B616_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979408">
        <property type="protein sequence ID" value="EXK77191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B616"/>
    <dbReference type="HOGENOM" id="CLU_2483471_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="87" mass="10096" checksum="FE02871A11A8E4D6" modified="2014-05-14" version="1">MTMDFRHGCLILHHNQYVAGGIIGLFILQDHGEISTRIHSSPTKMLWCFRGLCSISSKMWSLPLTSSVTPRRLYQFLKISRNCSWRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7G2</accession>
    <name>X0B7G2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_17211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the RNase T2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979367">
        <property type="protein sequence ID" value="EXK78100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7G2"/>
    <dbReference type="eggNOG" id="ENOG502SJHT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_268863_0_0_1"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018188">
        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00530">
        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938259" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="20"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="726"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="441"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="456"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK78100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1233" mass="135363" checksum="D1476D381364BD36" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0B850</accession>
    <name>X0B850_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Erythromycin biosynthesis protein CIII-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979371">
        <property type="protein sequence ID" value="EXK77956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B850"/>
    <dbReference type="eggNOG" id="KOG1192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_4_0_1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="2">
        <location>
            <begin position="311"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="434" mass="47054" checksum="BFAA6FD703A84499" modified="2014-05-14" version="1">MSPTHEKANKYRFLVHTLFQKSHTLIALPVVKELVRRGHQVAWLGNPSEESRIIDSGAHFIVTKDVAETDARLMANPIFDLEGVAKAFFADRLTAQVADLRRALAEFPADCILNDFAPQGAAALHALGEIPVYASITGTPLYTLSGAARHPPASAIGALLCMPPMLLPLINPQRAVLGLPPVKDEELPWLHCSPFLHLQASSPLLEFNQPVPETVHFLGSLAGSTQTVWEDPPEWWTKLNQEKDASRIIIGLTQGTLATDPSTLIIPVLEALKRSYGEFGGNVYLVVATPYAEQVKSNTASISRNTDGLRVHISAWVPYDLLLPYCNILITNGGYGGVMQALEHGVPLICVGTVADHADVGARVAWAKAGFNLQTDKPSEEQIREAVAKVLSDGSYKENAIRVGKQLKSLGGAHKAADELEKLTAQVWNCKVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8D8</accession>
    <name>X0B8D8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_16920</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658522">
        <property type="protein sequence ID" value="EXK78405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8D8"/>
    <dbReference type="HOGENOM" id="CLU_072368_0_0_1"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK78405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="37938" checksum="0D6472B9ED28CB34" modified="2014-05-14" version="1">MTFGRPSMIADWLSEAVPLPSMIDDDFLDTQIKPSAVRPDGRTTEVAFFIKSLELYSIVNDALRRLYMGPMETSGNSDEALTSVLQLDSRLTNWARSIPEQLSCAFKPDDEDFIFQRQRIVLRARYLHARILVLRPVVAEHYLKQAKPMDLQQHPRTDESVSKKLIDECFALCFEAAQETIDILHQNLDLETVTGPVPAWWFAVLFVYTAATVLLAKRLRPRSYDASLFEPWPIPTGWNQAIELLKAYARVGESAERCVAALEILASRIMDKSRVEEDLNGQQSLEETQESIIVQNPAGELPGFKGSSINFDFDGMDFDINDMLWLNSSAADILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8Y2</accession>
    <name>X0B8Y2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_16729</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979354">
        <property type="protein sequence ID" value="EXK78615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8Y2"/>
    <dbReference type="eggNOG" id="KOG2820">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_0_2_1"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051698">
        <property type="term" value="F:saccharopine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF26">
        <property type="entry name" value="L-SACCHAROPINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="10"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK78615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="429" mass="47335" checksum="4284262B015DC434" modified="2014-05-14" version="1">MSTENTSQSILILGGGCFGLATAFELARKGYKNITILEKDIDVPSRFSAAYDLNKVIRAEYADDFYTQLALDAIRKWQSDPLYTPHYHQTGFLNVTSGKAAQNTKGAVESYFQSLQKNPAFNGQTTRVNSSKEIKKLVPKFSGPLTGFTGYHNKLAGYGHSANALRAVYEQCVKLGVKFHLGTKDGEVESLLYASSREGTKCIGARTRGGTIHSADKTIVALGADAANILPRIGKQMTGRAWGVAHIQLTDKEAAELKGIPVTNVRDLAFFFEPDLKTKKLKFCHMGGAFTNYAFSKDGLSIPFPELADSQFMPLEDETHIRLLLKEVFPQLADRPLIDQHLCWFADTDDSDFIIDYVPGTNATLAVLSGDSGHGFKMLPIFGQFVHKLLVEEKQSQAKWQWKDSKPKAAAVWRSSESQELAAVPRAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB21</accession>
    <name>X0BB21_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979642">
        <property type="protein sequence ID" value="EXK76023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB21"/>
    <dbReference type="HOGENOM" id="CLU_2236820_0_0_1"/>
    <dbReference type="OrthoDB" id="5116474at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="105" mass="11454" checksum="74B71805E824EE5C" modified="2014-05-14" version="1">MCHTVIAQRMCKACRCSLGETVIDFTRCARKCSSPFYCLTPEPQMELCSLCPATATVSAPVLAHNVEDTYTTTAVASAGTRLYDHPFTKAAIYPPPVFTRHATAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBB9</accession>
    <name>X0BBB9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979832">
        <property type="protein sequence ID" value="EXK75769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBB9"/>
    <dbReference type="HOGENOM" id="CLU_211148_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="46" mass="5254" checksum="E6748FD8DA7735A6" modified="2014-05-14" version="1" fragment="single">MKGFRYNNLHPSDRRVNQLLRISSCAGIGMAMMRLKNMVVGSETRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC74</accession>
    <name>X0BC74_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979602">
        <property type="protein sequence ID" value="EXK76104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC74"/>
    <dbReference type="HOGENOM" id="CLU_3299441_0_0_1"/>
    <dbReference type="OrthoDB" id="5244857at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="42" mass="4666" checksum="96A282F7CF15526F" modified="2014-05-14" version="1">MMELVVHMDDVEGGISDTVPMGYNLGHDLGDFLKWQAENMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCV4</accession>
    <name>X0BCV4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_18946</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2"/>
    <dbReference type="EMBL" id="KI979543">
        <property type="protein sequence ID" value="EXK76309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCV4"/>
    <dbReference type="HOGENOM" id="CLU_011530_0_0_1"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000196">
        <property type="term" value="P:cell integrity MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000182">
        <property type="entry name" value="MAP kinase kinase kinase mkh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000387">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF48">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE BCK1_SLK1_SSP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="702"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="132"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="289"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="369"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="474"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="565"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="319"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="433"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="498"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="608"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="731"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK76309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1000" mass="109019" checksum="5D1DA9E7F2318443" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCZ1</accession>
    <name>X0BCZ1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979527">
        <property type="protein sequence ID" value="EXK76359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCZ1"/>
    <dbReference type="HOGENOM" id="CLU_3106386_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="51" mass="5732" checksum="955A92D03350F19B" modified="2014-05-14" version="1">MPSDSRTMREEMFEATTDDPVRQAGAGLAMLRDRKIYSLVLMAESLVELAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD76</accession>
    <name>X0BD76_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_15675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658461">
        <property type="protein sequence ID" value="EXK79751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD76"/>
    <dbReference type="eggNOG" id="ENOG502R6NB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009377_1_1_1"/>
    <dbReference type="OrthoDB" id="103819at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="102"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK79751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="721" mass="80778" checksum="F83F20707D746D23" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE14</accession>
    <name>X0BE14_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979460">
        <property type="protein sequence ID" value="EXK76694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE14"/>
    <dbReference type="HOGENOM" id="CLU_2812474_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="67" mass="7539" checksum="1DDE76EC92B44824" modified="2014-05-14" version="1">MSFQTLHHRQRRKRHPPTAAITYTRNVELGTNMLLPLQVPASGQPTLLMPPCRPVPGLRARLLAFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEV3</accession>
    <name>X0BEV3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658439">
        <property type="protein sequence ID" value="EXK80655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEV3"/>
    <dbReference type="HOGENOM" id="CLU_098704_0_0_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="1">
        <location>
            <begin position="3"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="215" mass="24186" checksum="C19DA267FB330C9A" modified="2014-05-14" version="1">MCIQYRLGAAGFLAGDDVKQDESRKVGLLDQRAALTWVQDNIHHFGGDRNKVTITGGCAGGGSVMMQLLFKGSEQNAPFRTAIPEYPWMAPMYSNDWLNQQYSGLLSAANCTDLACLRQISVDEFQAAAKVASIAAYDQSKFPYGTFYWNPTVDGKIIRDYPTRELQNGHFSKVPVLVDREGYEGYFFTNPYTQNETDEAEYLRDLLLEELRIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFK0</accession>
    <name>X0BFK0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFK0"/>
    <dbReference type="HOGENOM" id="CLU_2372866_0_0_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="95" mass="10450" checksum="E3059A3C4A300734" modified="2014-05-14" version="1">MHISTRQIIIWDEFGVSPGFHIQDLFYTFGTPATAMRPSQRSLQLAIASFVLKGMSVLDGRKEFPILGDEALLVNITAAGAMPSVPDNLNKTRCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGI7</accession>
    <name>X0BGI7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14619</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGI7"/>
    <dbReference type="HOGENOM" id="CLU_3050387_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="63" mass="7393" checksum="9E6F1E19BDFB85F1" modified="2014-05-14" version="1">MQPNCRMAHRGSCIIIYFQSPDELWGLDWIVSLEPTRSKGLRREKTRGYFTEFLQSSDKDQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGN2</accession>
    <name>X0BGN2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979334">
        <property type="protein sequence ID" value="EXK81295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGN2"/>
    <dbReference type="HOGENOM" id="CLU_133376_0_0_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="171" mass="19596" checksum="6FDB6DD7496BFAEF" modified="2014-05-14" version="1">MTLSTNWHAFQEIPGAIEALSTTWSTSYGQVHTGLDNGADKEIVNVKRQLATDRVKSLGLDHIPIEANTRPNLDFIRRYLNNVLEDNWIISKEGSSNADDMRYAACIMLDTEILAQLMQVPKDLPCNTTEHFRSPYWVNMVETKPNTNTNTKEAFRVALFGEFDLLHYWFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHI4</accession>
    <name>X0BHI4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979371">
        <property type="protein sequence ID" value="EXK77944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHI4"/>
    <dbReference type="HOGENOM" id="CLU_122502_1_0_1"/>
    <dbReference type="OrthoDB" id="5147020at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="131" mass="14795" checksum="7192D70565D8B075" modified="2014-05-14" version="1">MVKDARNANRTKVVCRDETEMQLIREVAEKTAVKGARALRDQLYPVKVDGANRTAVLNLSGNVLPGAAEALGKENDMTIPKMHWLSGKENRKTYGSMVVYVTKASDARRLLEERYFHLARESASTNIFERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIU9</accession>
    <name>X0BIU9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658503">
        <property type="protein sequence ID" value="EXK78778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIU9"/>
    <dbReference type="HOGENOM" id="CLU_019138_0_0_1"/>
    <dbReference type="OrthoDB" id="5047581at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022198">
        <property type="entry name" value="DUF3723"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12520">
        <property type="entry name" value="DUF3723"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="620"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="809" mass="93579" checksum="D45C92903AA587C6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJM6</accession>
    <name>X0BJM6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RTM1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_16283</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658483">
        <property type="protein sequence ID" value="EXK79078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJM6"/>
    <dbReference type="eggNOG" id="ENOG502SK3S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033465_3_1_1"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK79078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="33944" checksum="3792F76691C88DA8" modified="2014-05-14" version="1">MAAKCDPNYRHADWSFYRYEPSTAAAVIFVVLFSITTIVHVIQLIKTKTWYMLAFCLGGISEIAGYIGRAINSTEDPGCWTLGPYVVQSVLLLIAPALMAASIYMILSRVILLTEGEVHAVIRRRWLTKIFVVGDIISIELQSAGGSMMSGANEGNNLMKIGEYVIIGGLFFQLAIFGIFIVVVSVFHRRMNRSPTNKSLEPSIRWRHYLTTLYITSGFIWVRSLFRVIEYLDGNDGYLMRTEAFMFVFDATLIWIVMVWMNWYYPSEIGLLLRNEIPVANGFELLPFRQRFEKIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ53</accession>
    <name>X0BQ53_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11736</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ53"/>
    <dbReference type="eggNOG" id="KOG0069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_2_1"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12168">
        <property type="entry name" value="Mand_dh_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF281">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="3">
        <location>
            <begin position="31"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="128"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="355" mass="39241" checksum="B44A6C23BE4390D8" modified="2014-05-14" version="1">MAPKKPIVLRIGEDIKYNHDFYNNVFTKRFDVVANEEPDRESFIKALKENKYGQFSAIYRPHFQTGGEMGQWDEELISLLPPSVRIFASAGAGFNWADVDALGRRRIWYANGAGASDEAVSDTALFMILSVFRNFWLSQRGARTCDPAEFQRMHKLIATISYNPRGHVLGIVGLGNISKLVARKAGLALGMKIHYYDVVRSSPEVEEELQATYHSSLHELLGIADCITLHTPLNAHTQDLINKEAFAAMKDGARLVNTARGQIVNEDALIGALKSGKISAAGLDVHYHEPQVSKELAAMDNVTLTCHNGGAAITTRINFELMAMENILRVVDENGEFCGEPTTAVNRKAFEQASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ74</accession>
    <name>X0BQ74_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Amine oxidase</fullName>
            <ecNumber evidence="15">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_14902</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16153"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:228804"/>
            <dbReference type="EC" id="1.4.3.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="15">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="14">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="14 15">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="15"/>
    <dbReference type="EMBL" id="JH658440">
        <property type="protein sequence ID" value="EXK80629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ74"/>
    <dbReference type="eggNOG" id="KOG1186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011500_3_2_1"/>
    <dbReference type="OrthoDB" id="5379943at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.20:FF:000001">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.40:FF:000014">
        <property type="entry name" value="Peroxisomal primary amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049947">
        <property type="entry name" value="Cu_Am_Ox_Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008559">
        <property type="entry name" value="PRK11504.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF86">
        <property type="entry name" value="COPPER AMINE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01165">
        <property type="entry name" value="COPPER_AMINE_OXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 15" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="17">
        <location>
            <begin position="7"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase N3-terminal" evidence="18">
        <location>
            <begin position="98"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="16">
        <location>
            <begin position="225"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="13">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="14">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK80629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="682" mass="76843" checksum="F97FA119756DD43E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQZ9</accession>
    <name>X0BQZ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQZ9"/>
    <dbReference type="eggNOG" id="KOG0259">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_4_1"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43510">
        <property type="entry name" value="AMINOTRANSFERASE FUNCTION, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43510:SF1">
        <property type="entry name" value="AMINOTRANSFERASE FUNCTION, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="1">
        <location>
            <begin position="40"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="357" mass="39733" checksum="FD34AEA9AF37B942" modified="2014-05-14" version="1">MKFERMPIEIESPEEYGYDKIKYNLSESSVTDQTLESLDIKIPNLTLLYNEHRGETKLRKLIADDAGVSADDVLITSGAAGALFIITTSQLGSTPNSERNHLVVVRPNYATNLETPKAVGCEISYIDVTFENGFQPNIDEVEAAIKSNTRLVSVTCPHNPTGSTLSREALDRLVAITKKKGVLLLVDETYRDIAFAEKLPVAASMGNHVLSVCSLSKSFGMPGETFLAAKEQISISGSVINEWIAIDVLSRREKIMSDTTHEMRARLQMVESWIESEELLEWVKPTGGVVCFPRIKQEPKGGFSAFYERLLNKHATYVGPGHWFEMSDSFFRLGYGWPTREELEGGMKAISTALRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS85</accession>
    <name>X0BS85_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658422">
        <property type="protein sequence ID" value="EXK81778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS85"/>
    <dbReference type="HOGENOM" id="CLU_1111290_0_0_1"/>
    <dbReference type="OrthoDB" id="3519019at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="265" mass="29637" checksum="D734FD773E5A2CBA" modified="2014-05-14" version="1">MSRTKHFLPPLVGLIFAILAFVFSVLTITSREWAIRMNYDPDPNPQTWDKPTYTLYRSPFIICREEQVNSTDPNADPVYSVHCDHFKPYGHNKTTCELMNVTDSDVAENLGDQRLCQQIHLAGNYAIASTVFIGVGFLATMTLAFLSLLRSVSTHRHKHESDHRSNNRALPLLTLVTLAFLFVGFVTALISQFYGIMGFIVSLPNQSDFASSQGSGSSNEAEVHGFHGPWFQGKALSVYATLAWGFTIATGTMVSLTWRLPRWNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSF5</accession>
    <name>X0BSF5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSF5"/>
    <dbReference type="HOGENOM" id="CLU_1447733_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="187" mass="20773" checksum="5031D669B52AE895" modified="2014-05-14" version="1">MSYLTYRPKKSNARTPCHDLNIGRNHYSPSYTHQLSSSQFIKCRQNPIANFFALSSSKGSYSSSSGVGHIIAKISPPSSAIIASSSLPTRPISAMISLSDQLLHMRTRINPCSAGPVVMHIHLSSMSCGRWPFMRFIIFGPDKRMRHSALEGVSMDLTLMREPVNLFSVVMVKIFGGWIFGFETCNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTG6</accession>
    <name>X0BTG6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Triacylglycerol lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13856</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658422">
        <property type="protein sequence ID" value="EXK81784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTG6"/>
    <dbReference type="HOGENOM" id="CLU_012494_6_2_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="97"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="335" mass="36898" checksum="03CEEA9835F650C3" modified="2014-05-14" version="1">MSNQPPYPLHESVLDRIDPEYAAFYNKHIIDKQQVHLQPVEASRSSGILIPGSGPLQPVASTIDYAIKRKESEGPDVKVRCFTPIGDKPENGWPVCIYYHGGGWVLGTIDTENVIASHLCARGKCVVVAVDYRLAPENPFPAAVHDSWEAVLWVMGEGKKTLGLDTSKLATGGSSAGANLAAIMCQRAADRGSPKFSIQLLSVPVMDNTADATNNVSWKENQHSPALPAPKMLWYRHHYLPNKEDWSHPEASPIFWKGDFSKMPPACFVVGELDVLRSEGEQFAKKLQDAGVKAELNVMKGQPHPFIAMDAVLEAGSRAITLFCDALYKTMYEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTM8</accession>
    <name>X0BTM8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTM8"/>
    <dbReference type="HOGENOM" id="CLU_110322_0_0_1"/>
    <dbReference type="OrthoDB" id="5103436at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="172" mass="19747" checksum="00288E2020D036E2" modified="2014-05-14" version="1">MMLHSRPDSAKKFQGEMDRYKQSAEYQHPVMKKVISTLKENFDKAAKDMSVLLANNLASFVRYELTNLSSSVVAHITLCSVYNMVLFLFWEVEFPADKIIYPSNKSEEKQEILFIASSLDDRVEPEDEQSDSDDLAIARTTESSAPTHNSERAKMESRLADMEAHFLFIRNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTP4</accession>
    <name>X0BTP4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_10625</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTP4"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002220_0_0_1"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="584"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK85246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1073" mass="118401" checksum="282BD76C4B5DC9CB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTZ8</accession>
    <name>X0BTZ8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTZ8"/>
    <dbReference type="HOGENOM" id="CLU_158101_0_0_1"/>
    <dbReference type="OrthoDB" id="4972001at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="96" mass="10634" checksum="2B6964D02CE27DC4" modified="2014-05-14" version="1">MCIIYSTPKTCGNCEAEDIALTNTETCDAVKEGKACLGRHEIVINNAWLCPACKVNTARGPSYMEPYDYQPKIRQQASKKETGSFADKVKKMIGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV03</accession>
    <name>X0BV03_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV03"/>
    <dbReference type="HOGENOM" id="CLU_022730_0_1_1"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF279">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="37"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="456" mass="50242" checksum="6A2C82414D737B12" modified="2014-05-14" version="1">MSSKPFPAPNGMTSFWRSSPGSLDNHRSTKELPSQCDILIIGAGYSGASLVTHMLSQPESKDKSIVVLEARQLCSGATGRNGGHIKPDVYNLCLRMASKHCIDAGAEIAEFELANVEAVKNYVLDNKVDCDLMITQAVDVQLSEEHNALLKAGYDRLIKAGVSATKSAFYVDGKYAETVSGVKGAKGAFKYTTGHLWPYKLIHHMFAEALEHENLNLQTNTPVTSVSASPEADGSWSVTTSRGVIKARKIIMATNAYTAALLPEYHEKIIPYRAICSRIIAPNPPLLSDSYAIRFSPTDFDYLIPRPDGSIIVGGAKSAYFRHTEDWYGSVNDSKVIERAKDYFEGYMQRHFRGWEHSGAHTEQVWTGIMGYSADGLPRIGRVPGRKNMFIMGGFTGHGMPQVFLAAKGISRMVLEDLAFSDTEIPRLFEESEARLKSDENFLKDIIDAQLSLAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVU7</accession>
    <name>X0BVU7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_10071</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVU7"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000180">
        <property type="entry name" value="MFS monosaccharide transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF6">
        <property type="entry name" value="MSTA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="36"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK86021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="557" mass="61268" checksum="824041A5CBAD6AA9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWA7</accession>
    <name>X0BWA7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_09878</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWA7"/>
    <dbReference type="eggNOG" id="KOG2028">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017985_0_1_1"/>
    <dbReference type="OrthoDB" id="10265467at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18139">
        <property type="entry name" value="HLD_clamp_RarA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3710.10:FF:000005">
        <property type="entry name" value="AAA family ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000001">
        <property type="entry name" value="Putative AAA family ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000029">
        <property type="entry name" value="Replication-associated recombination protein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000137">
        <property type="entry name" value="Replication-associated recombination protein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3710.10">
        <property type="entry name" value="DNA polymerase III clamp loader subunits, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051314">
        <property type="entry name" value="AAA_ATPase_RarA/MGS1/WRNIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779:SF7">
        <property type="entry name" value="ATPASE WRNIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779">
        <property type="entry name" value="WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBZ4-type" evidence="13">
        <location>
            <begin position="2"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="173"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="31"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00056113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK86161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="553" mass="60377" checksum="B25984CC23689B13" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWX5</accession>
    <name>X0BWX5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658407">
        <property type="protein sequence ID" value="EXK83009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWX5"/>
    <dbReference type="HOGENOM" id="CLU_2121220_0_0_1"/>
    <dbReference type="OrthoDB" id="5103752at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="114" mass="12455" checksum="20F017D008DCEB33" modified="2014-05-14" version="1">MGVVRTRFLACHLSIPRDGAKRLRQRLTKAAPINGRHIRSLYVGVLAINGQLVYISSKKGEVYPNLFEDDDFTSLASKAEPSQTPAGSNTILIETNLIGGNLARNKQYVAGQTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXB3</accession>
    <name>X0BXB3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXB3"/>
    <dbReference type="HOGENOM" id="CLU_2497985_0_0_1"/>
    <dbReference type="OrthoDB" id="5072352at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936778" evidence="1">
        <location>
            <begin position="20"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="86" mass="9622" checksum="037116856176975A" modified="2014-05-14" version="1">MKLSIARIATLAATSQVTAWYMTFYDNTERCEVDGETEYQILEGEQSDCNTFAASMDGVDCIHFVEGGRNKKAARTCSKLNRQSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYK4</accession>
    <name>X0BYK4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-dependent oxidoreductase 2 FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYK4"/>
    <dbReference type="eggNOG" id="KOG2404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022946_0_0_1"/>
    <dbReference type="OrthoDB" id="3345469at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014614">
        <property type="entry name" value="KsdD_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009472">
        <property type="entry name" value="PRK12834.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260">
        <property type="entry name" value="3-KETOSTEROID-DELTA-1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260:SF1">
        <property type="entry name" value="KSDD-LIKE STEROID DEHYDROGENASE RV0785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036654">
        <property type="entry name" value="UCP036654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="3">
        <location>
            <begin position="9"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK86966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="578" mass="63730" checksum="543859895D66A6BA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZX7</accession>
    <name>X0BZX7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">26S proteasome regulatory subunit 4 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_09238</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZX7"/>
    <dbReference type="HOGENOM" id="CLU_000688_2_3_1"/>
    <dbReference type="OrthoDB" id="10255768at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000007">
        <property type="entry name" value="26S proteasome regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000039">
        <property type="entry name" value="26S proteasome regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 13" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="234"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="90"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK87441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="456" mass="50662" checksum="F0E016887A0509F1" modified="2014-05-14" version="1">MGQGQSGMGEGGRDEKDKKKDKPKYEPPPRPTTRVGRKKRKAGGTSAAQKLPAVYPTSRCKLRLLRMQRIHDHLLLEEEYVENQERLRKAKAAKEGQSVGTDADVDRLADERGRVDDMRGSPMGVGTLEELIDDDHAIVSSTTGPEYYVSIMSFVDKDLLEPGASVLLHHKSVSIVGVLTDDADPIVSVMKLDKAPTESYADIGGLEQQIQEVRESVELPLLHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLVRQLFQVAGENAPSIVFIDEIDAIGTKRYDSTSGGEREVQRTMLELLNQLDGFDDRGDVKVIMATNKIDTLDPALIRPGRIDRKILFENPDQNTKRKIFTLHTSKMNLNEDVDLEEFISQKDDLSGADIKAICSEAGLLALRERRMRVQMADFRSARERVLRTKQEGEPEGLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0M1</accession>
    <name>X0C0M1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Benzoate carboxyl methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0M1"/>
    <dbReference type="eggNOG" id="ENOG502T6SI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061841_0_0_1"/>
    <dbReference type="OrthoDB" id="1523883at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005299">
        <property type="entry name" value="MeTrfase_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31009">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE:CARBOXYL METHYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03492">
        <property type="entry name" value="Methyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="38573" checksum="5F8EEED5C4F168D2" modified="2014-05-14" version="1">MKADNVSMQGGGYYNENSNLQGQAIDKSLELLRPSGHQGLSMILADYGSSEGKNSVQLFSQYLKTLPSVTSATLVFNDTPSNDFSSLTLTIHQSWDTLSQGGSISINTLLSPRSYFEQVLPDGFVDAGFNFTALHWLRNMPDASSTPSSLSAAAHEDFVTFLSARHKEIRQHGTMTICIPSDGEISVLPTFRCFEASLRNLYDKYQVDPTIARRLPMYFRTLDEILTSIAAVDTKWSLKSRHNLPLMHTSWSPEVIEASSEEARMAGRKRYTDAVAGFALAACSQFFIDGLKPRGYQGESSEDEVIRLKERFMTDLTFAFKEEFLCTHCTDKVGFTYTLLQLERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0W6</accession>
    <name>X0C0W6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Secreted protein CSS2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0W6"/>
    <dbReference type="HOGENOM" id="CLU_099521_0_0_1"/>
    <dbReference type="OrthoDB" id="5059029at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046624">
        <property type="entry name" value="CSS2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20521">
        <property type="entry name" value="DUF6736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936111" description="Secreted protein CSS2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Secreted protein CSS2 C-terminal" evidence="2">
        <location>
            <begin position="58"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="205" mass="22486" checksum="D4A7758706028FEE" modified="2014-05-14" version="1">MKPALTNFFVLMSLPLFIYSMPTTEVTEVVNETEAVNEAVKMPDSLALYHLEDFESEDSALEKRRHVTVCERIITITSHCVIIGGAIKDGILQISAAIKHASNVKTCSTFTGHAGPNSNLFYRYRSTGRHCDTTAEQETIAGAIEHHIKNHGHKLCGTQCLELTHGGTWHGYLLIGPASNFDHKAYCGPEVSFKHCDSGGKGDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0C154</accession>
    <name>X0C154_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">acetyl-CoA C-acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_08748</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="4"/>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C154"/>
    <dbReference type="SMR" id="X0C154"/>
    <dbReference type="eggNOG" id="KOG1390">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_0_1_1"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000007">
        <property type="entry name" value="acetyl-CoA acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF165">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="12">
        <location>
            <begin position="7"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="13">
        <location>
            <begin position="272"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="10">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK87866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="396" mass="41144" checksum="1152EE6D260D6DC9" modified="2014-05-14" version="1">MANLPPVYIVSTARTPIGSFLGSLSSQTAVQLGAVAIKGAVERAGIKPEDVDEVFFGNVLSAGVGQGPARQCALGAGLPQTVIATTVNKVCASSLKAIILGAQNIMLGTSDIVVAGGTESMSNTPHYLPNLRNGAKYGDQTLVDGVLKDGLTDSFKKDHMGISAELCVQDHELTREAQDEYAINSYKKAQAATEAGLFTEIVPVEVPGGRGKPAIKVERDDEVKNLNVDKLKAMRPAFKPDGTVTAPNAAPINDGAAAVVLVSEAKLKELNLKPVAKILGWGDAEREPERFTIAPALAIPKAIKHAGLTADQVEYYEINEAFSAVALANMKILGLNPDQVNVYGGSVAIGHPLGCSGARIVTTLTSVLKEKKAKIGAVGICNGGGGASAMVIENLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1X6</accession>
    <name>X0C1X6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08253</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1X6"/>
    <dbReference type="OrthoDB" id="1747771at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000001">
        <property type="entry name" value="Fungal specific transcription factor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004507">
        <property type="entry name" value="UbiX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374">
        <property type="entry name" value="FLAVIN PRENYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374:SF1">
        <property type="entry name" value="FLAVIN PRENYLTRANSFERASE PAD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="65"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="615"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK88420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="751" mass="84389" checksum="907A1014A7B69D36" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2P7</accession>
    <name>X0C2P7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979420">
        <property type="protein sequence ID" value="EXK77062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2P7"/>
    <dbReference type="HOGENOM" id="CLU_432161_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="513" mass="58223" checksum="ABFCF81AF30192C7" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2Y5</accession>
    <name>X0C2Y5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Gem-associated protein 5 TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_18147</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658637">
        <property type="protein sequence ID" value="EXK77142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2Y5"/>
    <dbReference type="HOGENOM" id="CLU_000799_2_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034605">
        <property type="entry name" value="PGC-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056421">
        <property type="entry name" value="TPR_GEMI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15528:SF11">
        <property type="entry name" value="FI18188P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15528">
        <property type="entry name" value="PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23774">
        <property type="entry name" value="TPR_GEMI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Gem-associated protein 5 TPR" evidence="8">
        <location>
            <begin position="449"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="324"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="756"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="756"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="777"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="805"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="821"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="858"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="871"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="902"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="924"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="949"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="979"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK77142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="988" mass="107865" checksum="A69D7E73B4613160" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4M5</accession>
    <name>X0C4M5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658584">
        <property type="protein sequence ID" value="EXK77687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4M5"/>
    <dbReference type="HOGENOM" id="CLU_057547_1_0_1"/>
    <dbReference type="OrthoDB" id="4500473at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="280" mass="30380" checksum="7C5A3405857383A4" modified="2014-05-14" version="1">MASFSSQPSFHLCPDFNIPPPPDGHLELGSVLRGLDFNSVYSPLDAGGAVEIPDAQLKPISEKTGFSRALKELRGVEGSIWAKIFGSDGLGAMFSFLRKRENDETLTVKKLLVQYFIPTPEYMKKALEIDNVALHVNATKRKKPVYLVTGLMWTEGAKLSKVQSSRSKASGQAAATDPHSGTTGGASGTYEGEESFSSSFDGATPFILGIRVRKIWWGRDGVRREEEDIVGATLGDSKEMNEGVLDGLRYADDEVVNAAGQNIVDESQLGEVDPVTWILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C535</accession>
    <name>X0C535_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C535"/>
    <dbReference type="HOGENOM" id="CLU_3299399_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="40" mass="4362" checksum="E0EF3F69745FA04B" modified="2014-05-14" version="1">MAACQSQHHSHVQKVKRNLYMLQIIRALGGSPSSVSTPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5M0</accession>
    <name>X0C5M0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ZN622/Rei1/Reh1 zinc finger C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09762</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5M0"/>
    <dbReference type="eggNOG" id="KOG2785">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018787_2_0_1"/>
    <dbReference type="OrthoDB" id="19329at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZN622/Rei1/Reh1 zinc finger C2H2-type" evidence="2">
        <location>
            <begin position="49"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="322" mass="36842" checksum="61405232F0C93C9B" modified="2014-05-14" version="1">MLGATTTTATTTTTSMILPFSEETSPLTPYIMSINNSPDPAPQSFTPGQCLFCPSAYPTLAESILHMQSAHGLFVPYQQHLLVDLETLFRYLHLVIYEYRECIYCGTSRTTVQAVQQHMMGKGHCKFDVSEGSEFADFYDFSQTSVDPDEDDLSEDDEEEFESAEVEPDRKPVQVDRDSIRLPSGRLISKRLSAQVEPSVSQMRERKRTSRSQLEYSSVEVDEEVPMPEEHVPDTSDTRLLSRRERRQKATVTYQLANMSAGDRSALMHLSASEQRSLIATQHRFTEKVQKEESRRQRRIDRKGNKNLYAYWHTETPVYQCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0C600</accession>
    <name>X0C600_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ERF1 methyltransferase catalytic subunit MTQ2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_09492</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic/archaeal PrmC-related family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C600"/>
    <dbReference type="eggNOG" id="KOG3191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018398_6_1_1"/>
    <dbReference type="OrthoDB" id="406152at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035657">
        <property type="term" value="C:eRF1 methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000274">
        <property type="entry name" value="ERF1 methyltransferase catalytic subunit MTQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052190">
        <property type="entry name" value="Euk-Arch_PrmC-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875:SF1">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK86628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="27755" checksum="7E3CB81379DF0450" modified="2014-05-14" version="1">MLPTPDTSHVPYERVYEPAEDSYLLLDTLSSAAETEYLQKAFPDIAPLVVEVGTGSGVVLAFVHAHAQKLFGTREVLTAGIDMNAFACRATVGTVAKAASDNPDSHAFYLGSCMGDLTTPWREGTIDVLIFNPPYVPTPEMPARPDSFTADDLAVSTKPSFDDDSYLLALSYAGGLDGMETTDRLIEALPQTLSRRGCAYLLLCAQNKPDQVKSRIEGFGPEWRARTVGNSGKQAGWEKLQIVRIWRDYSKTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6M8</accession>
    <name>X0C6M8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING zinc finger-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09602</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6M8"/>
    <dbReference type="OrthoDB" id="5405791at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056929">
        <property type="entry name" value="Znf_RING-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25080">
        <property type="entry name" value="zf_RING-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939166" description="RING zinc finger-like domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="RING zinc finger-like" evidence="3">
        <location>
            <begin position="434"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK86843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="494" mass="54510" checksum="1B6F17CB3C673EBA" modified="2014-05-14" version="1">MHWCKSLGIAFVSCSALSCPAAGLELPSLHPPTLHRHVLPLTALVPQLRKHVPVTPCNGTHSILNVQLQEKRYRSMQEHIRRAHPEHYISKLPATEESFLLMINTPPSERRPLDQTSAPNAQGLSHSHSSLPPPIDHLQGFHERHNYHRDEPSNPGTPRLLDDFSNGGPVSGPMLGTASAAAALAELHGVKSERDMDLDGDYYSDMDVRRRPRTSIELPPLNLSNHDITSDPYSSAKSNRQRDFLPSILANSPPGRSSTLPPLQRSVGPNRPRKQSVTKRGREPHHKKKNSKGSATDWLRRIQNEERYRPGNDRKALSAEPSADFGKRWEDLIDAADQAASAAGDIDEDRTPVPQSPVSMHRSSLPPFSHQPQFQPASYQASPLQQALTPPSYGQDAVEPFPSVESGESGDNFHMGTRGLSDSSPTYSAQNIQIYCAACQGFSLLKDSYACTECICGLCPTCVEVLMTEHGARRKCPRCATIGGRFKPFQLDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0C700</accession>
    <name>X0C700_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycoside hydrolase family 5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09342</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C700"/>
    <dbReference type="eggNOG" id="ENOG502QPU8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009024_1_0_1"/>
    <dbReference type="OrthoDB" id="9971853at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050295">
        <property type="term" value="F:steryl-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904462">
        <property type="term" value="P:ergosteryl 3-beta-D-glucoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF5">
        <property type="entry name" value="ERGOSTERYL-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="772"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5 C-terminal" evidence="6">
        <location>
            <begin position="639"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK86978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="796" mass="91355" checksum="279835AE30E8DD28" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8R5</accession>
    <name>X0C8R5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8R5"/>
    <dbReference type="HOGENOM" id="CLU_145537_0_0_1"/>
    <dbReference type="OrthoDB" id="5044586at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="143" mass="15699" checksum="B8E41EB107137392" modified="2014-05-14" version="1">MSLVLTPMKMEAWLRLNGKSSRGLLAIYGSSVLGVLLTLYWTGLVIYHIYFYSLASYLGPLLATSTPKDIYGHAAGKKQNGAGFSRLCIGSDRDPQNHRNMKQSLTAAFFNKTLKIIANVVDVFADEIGELGEPKLNGLNMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8W2</accession>
    <name>X0C8W2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lignostilbene dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_16242</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658481">
        <property type="protein sequence ID" value="EXK79137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8W2"/>
    <dbReference type="eggNOG" id="KOG1285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016472_6_2_1"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF89">
        <property type="entry name" value="CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK79137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="59093" checksum="D547AB7D9B22C248" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9S0</accession>
    <name>X0C9S0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658471">
        <property type="protein sequence ID" value="EXK79437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9S0"/>
    <dbReference type="HOGENOM" id="CLU_3279557_0_0_1"/>
    <dbReference type="OrthoDB" id="5424209at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="41" mass="4653" checksum="E7F3107C7C72FAE3" modified="2014-05-14" version="1">MITAGLRNQDNADGFDVTYATAMQWLLDDIKRHGYDVEPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB29</accession>
    <name>X0CB29_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB29"/>
    <dbReference type="HOGENOM" id="CLU_3125051_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="50" mass="5600" checksum="A972DACD9928C4F5" modified="2014-05-14" version="1">MSYTVAKARIHRNSNLPKDNSSGLFNRSQVFPTVSINPLSGPVWSQRKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCI1</accession>
    <name>X0CCI1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCI1"/>
    <dbReference type="HOGENOM" id="CLU_900281_0_0_1"/>
    <dbReference type="OrthoDB" id="5035892at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="309" mass="33199" checksum="79BFCCBAB3809632" modified="2014-05-14" version="1">MTETFITTFPTTPSPTWTLPRFTPPPECLDTNSIWNMETDCYSGTAQGLYRTTRTCNYLWLGYTDYPHTTGGPGLGLNGFCGPGWSHPATECPVGYTPAHTVDYTPDATTSREILCCLTGYDFEWSRPTLTDQSGSSATPYDKFCIASNLKPSGTSPLTLTAFDLSSASSLQTDIRVSTTIKFDPEKDLLLASAVTISYQINPGGTTCVPDCDDPYTGGPWPRPAQTVTPAPESSRSDSGLVGLEKLVWVGIAFGIVVGLGIIACIGCRIHRSRKGKRMGATSEAQGHEGEVQDQDAIAMEAPKGKKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCN9</accession>
    <name>X0CCN9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acyl-coenzyme A diphosphatase SCS3</fullName>
            <ecNumber evidence="8">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">FIT family protein SCS3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SCS3</name>
        <name evidence="8" type="synonym">FIT2B</name>
        <name evidence="11" type="ORF">FOQG_08393</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65568"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57368"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:156554"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(9Z)-octadecenoyl-CoA + H2O = S-(9Z-octadecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65564"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:156553"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:50044"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:132023"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>hexadecanoyl-CoA + H2O = S-hexadecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:50032"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:132018"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCN9"/>
    <dbReference type="eggNOG" id="KOG3750">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048143_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03231">
        <property type="entry name" value="SCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019388">
        <property type="entry name" value="FIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046400">
        <property type="entry name" value="SCS3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129:SF0">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10261">
        <property type="entry name" value="FIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK88604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="326" mass="35797" checksum="8BE4C2BB0B5144FA" modified="2014-05-14" version="1">MVTTRRAARAAAEANDTVMDSPSRSTSTPRSSPFLPTPLERAGLVLFPALLIFGTIFSILSPQTRAAPYDPIAQSHLQDPSVSPSYFARKSNIFNVLFVKRGWAWITVAFFVFIFSHPSTTDTGRRVRASLRWVAVTTMWFLVTQWCFGPALIDRGFRWTGGRCELARREIEFGSDTVGDKVTAVACKAAGGKWKGGHDISGHVFLLTLGTAFLMQEVGWAVLRWSGKRNEERCVVMTDGALKSANVESDTSLGEGSERPALGLGGKFAVGVMGLSAWMLLMTAIYFHTWFEKFTGLLTAVTAFYVVYIVPRFVPAVRQVIGLPGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD38</accession>
    <name>X0CD38_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FACT complex subunit POB3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_06033</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the SSRP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD38"/>
    <dbReference type="eggNOG" id="KOG0526">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017374_3_0_1"/>
    <dbReference type="OrthoDB" id="498543at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035101">
        <property type="term" value="C:FACT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13230">
        <property type="entry name" value="PH1_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13231">
        <property type="entry name" value="PH2_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13229">
        <property type="entry name" value="PH_TFIIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.220:FF:000003">
        <property type="entry name" value="FACT complex subunit POB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000146">
        <property type="entry name" value="FACT complex subunit POB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000310">
        <property type="entry name" value="FACT complex subunit POB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.150:FF:000001">
        <property type="entry name" value="Fact complex subunit ssrp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.220">
        <property type="entry name" value="Structure-specific recognition protein (SSRP1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013719">
        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050454">
        <property type="entry name" value="RTT106/SSRP1_HistChap/FACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048993">
        <property type="entry name" value="SSRP1-like_PH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000969">
        <property type="entry name" value="SSRP1/POB3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035417">
        <property type="entry name" value="SSRP1/POB3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024954">
        <property type="entry name" value="SSRP1_DD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038167">
        <property type="entry name" value="SSRP1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849:SF1">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21103">
        <property type="entry name" value="PH1_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17292">
        <property type="entry name" value="POB3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03531">
        <property type="entry name" value="SSrecog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00887">
        <property type="entry name" value="SSRCOGNITION"/>
    </dbReference>
    <dbReference type="SMART" id="SM01287">
        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="12">
        <location>
            <begin position="374"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="482"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="491"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="537"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK92081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="564" mass="63142" checksum="047836883A6B0385" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE36</accession>
    <name>X0CE36_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phospholipid-translocating ATPase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_05722</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE36"/>
    <dbReference type="HOGENOM" id="CLU_033465_3_0_1"/>
    <dbReference type="OrthoDB" id="5384040at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF15">
        <property type="entry name" value="LIPID TRANSPORTER ATNI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="299"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="336"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK92655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="39027" checksum="B1A19BCA6E76EA56" modified="2014-05-14" version="1">MSTTTFTSTATTTSSATATCTTAVPGKYGRVPVDACNANYFFDPSFAANLAFCVLFGMTTMVHLIQAILFKKKFCWVAIMGATWETIGFAFKTLGSRNQQNMTYLIWGQLFFLLAPLWINAFVYMAVARMVYFRMPDRKLLGIKAIRMTLLFVWLDIILFLVQGAGGSMLSNNDDMNVIRIGQKLYMAGVGLQLAVIVIFIGITAFFYFKLRQLEGRSMGRMKWLILTMLAVLILIVIRIVYRLIEFGPGVNEHNQLLIHEEYPLGLDATPILIALVLLNIMHPGFVLRGPDSEFPKLSRKEKKALKQQKKMEKKQAKEAKKARKAGAQELKNLSYEGQSNSSNELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF58</accession>
    <name>X0CF58_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF58"/>
    <dbReference type="HOGENOM" id="CLU_1835272_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="140" mass="15186" checksum="7F0813B1A4F47F9A" modified="2014-05-14" version="1">MASVGAMNSEGLWCWPCEEGSTIHDTMDNNLCLFLSLGCHRLFLQAGMDGVSQPASLLTLSAFQASENWGQAEYSSPTETNKAIRCSGLTQQTRSGHARTTIFNAPTTVCIPELGWAGLGWLALGLIFAKLLVWRVHDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFW4</accession>
    <name>X0CFW4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14053</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658426">
        <property type="protein sequence ID" value="EXK81521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658426">
        <property type="protein sequence ID" value="EXK81522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFW4"/>
    <dbReference type="HOGENOM" id="CLU_008511_1_1_1"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF3">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="78"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="677"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK81522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="759" mass="84406" checksum="D6A25944EB21A9A5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFY0</accession>
    <name>X0CFY0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BNR/Asp-box repeat domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658426">
        <property type="protein sequence ID" value="EXK81537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFY0"/>
    <dbReference type="eggNOG" id="ENOG502QW46">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036301_0_1_1"/>
    <dbReference type="OrthoDB" id="2130735at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792">
        <property type="entry name" value="BNR/ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792:SF3">
        <property type="entry name" value="BNR_ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939385" description="BNR/Asp-box repeat domain protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="42142" checksum="71E8C659DAB02B32" modified="2014-05-14" version="1">MRFQSLLWGGLLSLSAVLAAPTANQEPPTPAKRAVPTSTFSNNVIFSPPSNAGWTDPRVLYARSIQLSDGSLLATWENYSPEPPLVYFPIYRSTDGGVKWTEIGKVQDTVNNWGLRYQPDLYELPRAIGKYPKGTILCTGNSIPTDLSKTKIDVYASTDGGKTWKFASSIASGGEARPNNGLTPVWEPHMMVYQDKLVCYYADQRDPKHGQKLSHQTTTDLVSWSSLVNDVADSNYNARPGMPGIALLPNGQYIFVYETCGTQGCRIFYRLTSNPLNILAAKEYALVSNKGTRPVSSPTVVWSSVGGANGSIIVSAGSQSQIFVNKNLGAENSWIEFATPQPNAYTRGLMVFKENDNFLAIIGGGWLPPSSTNQVSLSVIDLKKTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGD0</accession>
    <name>X0CGD0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGD0"/>
    <dbReference type="HOGENOM" id="CLU_3392349_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3595" checksum="7E40D76F564C5E3D" modified="2014-05-14" version="1">MTKKNLRKTNATSYLTSRELKIPAMATVRSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CH42</accession>
    <name>X0CH42_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_13681</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658419">
        <property type="protein sequence ID" value="EXK81922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CH42"/>
    <dbReference type="ESTHER" id="fusof-f9f4n3">
        <property type="family name" value="Carb_B_Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_16_0_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="18"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK81922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="511" mass="55348" checksum="B86B5EDE43E46927" modified="2014-05-14" version="1">MSKQPSSTQDRLENQTSDPIVRTESGDIRGRTAGDVHVFKGVPFAAPPFGPNYLRPPQPPEYWRGVRDTLRFGPKSPQVPYPPGIAQGLAELVGTGEDCLTLNVWTPSLRTAGRPVMVWIPGGMFEFHATGAVAYYDGGRFARDGVVCVTINYRVGAQGFLYLADGVPNLGLLDQIAALEWVQKNITAFGGDPGRVTIFGESAGAMSVATLLAVPKAKGLFRRAIVQSGSNPKLNSAATAKRIGQRLAEILGIEATWEAINATSSDRILHAQAQLRDNLVAHPDPAFWGEVALSFLPWAPIIDGDILPVHPIDAMRAGAAADIDLVVGSNTEETRLFLVLDGSIDRITEESLSAIAGLYGLPQEGLDAYRLLHPGASTGELFSAIQTDWFWRIPAIRFADAHAKTARALTYMYEFAWQSPQMGGRLGASHSLEIPFVFDTLGLGTEPLLGPTPAQELADAMHQAWAAFATTGDPGWPKYDAKRRSTMHFDMASRAVDDPLDKKLKLWDSVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHY6</accession>
    <name>X0CHY6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502RPIZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004198_1_0_1"/>
    <dbReference type="OrthoDB" id="5422628at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="844"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1268"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1326"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1401"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="853"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1353"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1405"/>
            <end position="1431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1431" mass="162519" checksum="EC3884C2F254D80B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJF7</accession>
    <name>X0CJF7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADPH-dependent diflavin oxidoreductase 1</fullName>
            <ecNumber evidence="9">1.18.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">NADPH-dependent FMN and FAD-containing oxidoreductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TAH18</name>
        <name evidence="12" type="ORF">FOQG_04433</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2 oxidized [2Fe-2S]-[protein] + NADPH = 2 reduced [2Fe-2S]-[protein] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67716"/>
            <dbReference type="Rhea" id="RHEA-COMP:17327"/>
            <dbReference type="Rhea" id="RHEA-COMP:17328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with DRE2; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion</location>
        </subcellularLocation>
        <text evidence="9">Relocalizes to mitochondria after H(2)O(2) exposure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the flavodoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJF7"/>
    <dbReference type="eggNOG" id="KOG1159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_17_6_1"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160246">
        <property type="term" value="F:NADPH-iron-sulfur [2Fe-2S] protein oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000013">
        <property type="entry name" value="NADPH-dependent diflavin oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000034">
        <property type="entry name" value="NADPH-dependent diflavin oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03178">
        <property type="entry name" value="NDOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028879">
        <property type="entry name" value="NDOR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF10">
        <property type="entry name" value="NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0274">FAD</keyword>
    <keyword evidence="4 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 9" id="KW-0521">NADP</keyword>
    <keyword evidence="8 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="10">
        <location>
            <begin position="8"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="210"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="61"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="388"/>
            <end position="391"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="429"/>
            <end position="432"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="528"/>
            <end position="529"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="534"/>
            <end position="538"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="598"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK94311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="603" mass="68648" checksum="2BE02CAF1B9A2081" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJF9</accession>
    <name>X0CJF9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJF9"/>
    <dbReference type="eggNOG" id="ENOG502SDNF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048597_0_0_1"/>
    <dbReference type="OrthoDB" id="5236270at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="446" mass="48463" checksum="E99D5677D8936359" modified="2014-05-14" version="1">MAINEVDKYLWLAYCKAVQNAVGGLPGHKPALFFTKHAQKAPVASQDIDPAYTNYGINNIINNFLQTNDLFYDPAHHKTYTQCLLEYLMAVKIGEGDQVRVTMIGRTLASALDQALRERDRALETFEKEEGYGLTGEQDFSQWWPSHAPAYSAAKQKVEAAAADYQAVLLNTGGPTASSLARGFNRIVKALIGGQSVPGITMPACHASADITRELLERDRTPHAITYVPEWMSLQYTAQVEHWMNGVGDGDSSTQINVADGREVNESDFGHAATDGFSYGPWLSFSAGKGSTNERSVSFGSMDTDTNLDVQFSYDEIQTICVPAGDWNVPSPGRRYQLSNTASEESRNLAFPDYLVVVRNLGFKVSIRDNKVAGQIDNLFDEAKSSGGSVRVFGIPATPDGSPDKATEENAHVAEWDLGAGMLSIRPTTDAGFASVVALVGELNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJW8</accession>
    <name>X0CJW8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rtm1p</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_04538</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJW8"/>
    <dbReference type="eggNOG" id="ENOG502QURG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033465_3_3_1"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF32">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK94486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="31720" checksum="65A400F51A2F5112" modified="2014-05-14" version="1">MQDQESIWMYDPSFPLAVVGTVVYGIIFLAIAYLTLIKYRAWYFIVVVIGSAIEVAAYSLRIHSVQNQSEITPFVLTLTYTVLAPVLIAAGNYLLISRLILAVLPPSHHRILRIPGRRLTPIFVFCDVIAFLIQGSGSGIASSDNWQGEMERIGVKVLIVGLVFQLAAFSLFLCVFRRFHVLALRMAVEDAPRGWQKVVLAVYISSILIMARCIFRVVEFAGGRDTYAFSHEWLFWVFESLPMAGAIGIFCFYHPSRYLGRNGGRHKSVRTEDTIELAQGHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKQ2</accession>
    <name>X0CKQ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKQ2"/>
    <dbReference type="HOGENOM" id="CLU_037438_1_0_1"/>
    <dbReference type="OrthoDB" id="4358152at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="51731" checksum="9398F53629B2183E" modified="2014-05-14" version="1">MPSYTMSAPGFQQAASLETLPPEVLLPIVKNLPGLDTLWDLMKVSPHIWRLFNDHAVTIVNAILSGPNAILIPEIANAVRAVLLVRSKAHPFRNLYDLQIRFLRSLFPRSTLGDSGSNPDPILVDREMMSVAAPPTVVVRSVVATVAHINALAQAFLTSCLERVRDPGFRPLHLVNPDNRYTSLYRPDPDGKRIRAWDQVFEGEPAKVTDAGQPTWVEEMRAVRALWVLQLIGEMKGQKESLGWSTEDVEKLGRMEAADFADAVEGNPAMASEEVRSVMEYLETLGDLTQDTYYQLPSPPRFTRWITAPPNLSPQFAKITHHRKDGSTFTRVEKTEDYSWGRTKENLGYDAPGMSIFKGLSKPRHHPTGGASPIEGVKFNSFRPLGFAFWDAWRMHLLGMHSPVGKHWYGNDTFYFFAWESVLPCDEVASIKARLRERRKEELDERQEAQRRSRGTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKU8</accession>
    <name>X0CKU8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">FOQG_05936</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25 14">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKU8"/>
    <dbReference type="eggNOG" id="KOG0214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_5_1_1"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14 23" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="19">
        <location>
            <begin position="35"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="18">
        <location>
            <begin position="238"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="20">
        <location>
            <begin position="504"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="21">
        <location>
            <begin position="603"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="22">
        <location>
            <begin position="705"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="16">
        <location>
            <begin position="796"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="1170"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="742"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="742"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EXK91933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1270" mass="143834" checksum="0D111199B511F815" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLP3</accession>
    <name>X0CLP3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12333</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLP3"/>
    <dbReference type="MEROPS" id="S10.008"/>
    <dbReference type="eggNOG" id="KOG1282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008523_10_3_1"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF453">
        <property type="entry name" value="S1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152161" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK83472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="473" mass="51520" checksum="9A5846055EAC5DB8" modified="2014-05-14" version="1">MKTALLNVLTALAFVGQGSCTPAASLDKRYLQEDGGIKYKVFEHAATGSKTKIVSNSGICETTPGVNQHSGYFSVGDNMNMFFWFFESRKDAKTAPLALWLNGGPGCSSMIGLFQENGPCTFNNGGSKPTLNPNSWNTFANMLYVDQPIGTGFSYGTDDAVSTLAAAPRVWNLLQAFYAQFPEYENRDFGLFTESYGGHYGPEFAFYFEQQNAAIDAGKIKGEKINLVALGINNGWIDPGNQYRDYIDYAANNTYRKLITPTQYSKYLNTYNQKCVPAFAKCPGLTGNDAACGNADDVCSSAIESPLERLADFDVYDIRASSNDPFPPATYSTYLTSASVMNAIGAQSDYQECGDDSYNKFIASGDRGRSFLPTLSQVIDSKITVLIWAGDADWICNWMGNYRALNSIAPQSFVSAPLKSFTVGGKKYGEFKTSGNLSWLRVYGAGHEVPAYQPEAALAAFIATMSKKPISST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM32</accession>
    <name>X0CM32_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_04065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CM32"/>
    <dbReference type="eggNOG" id="ENOG502SFG8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_4_0_1"/>
    <dbReference type="OrthoDB" id="5340195at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF289">
        <property type="entry name" value="GLYCINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="3">
        <location>
            <begin position="27"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK95500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="377" mass="40649" checksum="3FC15DDD95D72105" modified="2014-05-14" version="1">MSDGRYSSQSENKKPQVSDMSVANSNVVVVGGGIVGASIAWHLSSETNVTIIAEDIGGVATPNSFAWLNAASSDKKFYYDFRLRSLEHWREIEKAVENLPIHWGGTTSWDKSPRELEEEQKNLNAWGYDVIRVDKTEISKREPRIEETKLPEWGLGYDQEGALEAEKAAELLISLAKDSGAKVLETKVKGFTKTDGHISGVTLSSGETIPADHVVVAAGLGSVSLLASQNIPLPLKSTAGLLVNTKPTPKQLINGVINAPELHIRQTLDGALLFGSSYAGGDLGDDPEKTARELFAKLQKSVIGGEELEFSHYTIGHRVLPEDGLPILGETGLDGLSVAVMHSGVTNGALVGKLLSRQILTGETDPILENFRLDRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNB9</accession>
    <name>X0CNB9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="20 21">NADPH--cytochrome P450 reductase</fullName>
            <shortName evidence="20">CPR</shortName>
            <shortName evidence="20">P450R</shortName>
            <ecNumber evidence="20 21">1.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">cprA</name>
        <name evidence="24" type="ORF">FOQG_05527</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">54005</strain>
        </source>
    </reference>
    <reference evidence="24" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="20">This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19 20 21">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="20">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="20">Binds 1 FAD per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="20">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="20">Binds 1 FMN per monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="20">Endoplasmic reticulum membrane</location>
            <topology evidence="20">Single-pass membrane protein</topology>
            <orientation evidence="20">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="20">Mitochondrion outer membrane</location>
            <topology evidence="20">Single-pass membrane protein</topology>
            <orientation evidence="20">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="20">Cell membrane</location>
            <topology evidence="20">Single-pass membrane protein</topology>
            <orientation evidence="20">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="20">Belongs to the NADPH--cytochrome P450 reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="20 21">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="20">In the N-terminal section; belongs to the flavodoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.4" evidence="20 21"/>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNB9"/>
    <dbReference type="SMR" id="X0CNB9"/>
    <dbReference type="eggNOG" id="KOG1158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_17_3_1"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06204">
        <property type="entry name" value="CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000009">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000100">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000111">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000024">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000018">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03212">
        <property type="entry name" value="NCPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023208">
        <property type="entry name" value="P450R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF17">
        <property type="entry name" value="NADPH--CYTOCHROME P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000208">
        <property type="entry name" value="P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 20" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 20 21" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 20" id="KW-0274">FAD</keyword>
    <keyword evidence="3 20" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 20" id="KW-0288">FMN</keyword>
    <keyword evidence="2 20" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14 20" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="16 20 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="15 20" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 20" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="9 20 21" id="KW-0521">NADP</keyword>
    <keyword evidence="12 20 21" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 20" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="18 20" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="13 20" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="17 20" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="22">
        <location>
            <begin position="65"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="23">
        <location>
            <begin position="273"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <begin position="71"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <begin position="122"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <begin position="448"/>
            <end position="451"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <begin position="466"/>
            <end position="468"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <begin position="483"/>
            <end position="486"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="549"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <begin position="611"/>
            <end position="612"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <begin position="617"/>
            <end position="621"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="653"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="691"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRNR" id="PIRNR000208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EXK92329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="692" mass="77019" checksum="1295D41BC9C8BDE8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRF9</accession>
    <name>X0CRF9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1446 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRF9"/>
    <dbReference type="eggNOG" id="ENOG502QS8D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012617_0_1_1"/>
    <dbReference type="OrthoDB" id="10265871at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056362">
        <property type="entry name" value="AtuA-like_ferredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585:SF2">
        <property type="entry name" value="DUF1446 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11420)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23544">
        <property type="entry name" value="AtuA_ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="AtuA-like ferredoxin-fold" evidence="2">
        <location>
            <begin position="494"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="66131" checksum="7B60A22AE5C7532F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS95</accession>
    <name>X0CS95_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS95"/>
    <dbReference type="eggNOG" id="KOG3043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_2_3_1"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF105">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G08790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="277" mass="30636" checksum="D6834930A80EF77F" modified="2014-05-14" version="1">MPCADCYTGHDHPGPVYGREAKLHGHDVYVTEPQTKEVSTKGLIVVMSDAFGWNTTNLRGVADRYAERTGCRVYVPDFMHGTSAPASVKAVIDSVLNDGGFWGWLVKPWNLLKAAFVMVPFSIRNKPEKRYPGIRKFMDDLRCNEAANLKVGVVGFCWGAYGITHLAHGEVAANGKTIIDAAFTAHPSEIEVSRDIEPVKLPYSMVIGDIDFALPLKEVQKAAEILESKKGVDTEVVLIPNAKHGFAVRGNPDNEEEKDMADQAEDQLVRWFTKYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT79</accession>
    <name>X0CT79_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Guanine deaminase</fullName>
            <shortName evidence="8">Guanase</shortName>
            <ecNumber evidence="8">3.5.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Guanine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_04278</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>guanine + H2O + H(+) = xanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:14665"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; guanine degradation; xanthine from guanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.3" evidence="8"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT79"/>
    <dbReference type="eggNOG" id="KOG3968">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_0_0_1"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="UniPathway" id="UPA00603">
        <property type="reaction ID" value="UER00660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008892">
        <property type="term" value="F:guanine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006147">
        <property type="term" value="P:guanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000022">
        <property type="entry name" value="Guanine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014311">
        <property type="entry name" value="Guanine_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02967">
        <property type="entry name" value="guan_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF6">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="78"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK94084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="464" mass="51481" checksum="7F509531FC0B6991" modified="2014-05-14" version="1">MTGLKKQVFVGTFISSKNPKELDYQHDTIVCVDGEGRIVKVDTEGGSTEQIGKRLRETLDWELSDVDVHIAKPGQFFFPGFVDSHVHASQYPNVGIFGKTTLLDWLEKYTFPLESSLKDLSKAKRVYGSCVRRTLSHGTTTAAYYATIDVAATNLLADLCLEIGQRALVGRVCMDNPDMCPSYYRDESVEEGLEKTRQTIRHVQKIDPEFKLVSPVLTPRFAPTCSSKSMKGLAKIQKELDLPVQTHVSENEGEVELVARLFPESESYTQLYDDCGLLTTRTILAHAIHLTEAEAKLIAQRGSKISHCPCSNSSLTSGSARVRWLWDKGITVGLGTDMSGGYSPSILEAARQAALVSRHVAMGMDEEKERSKLTVEEVLYLATRGGAEVVGLADRIGGFEEGMEWDAQLIGLGSVDEDGVAEDDGNVNVFGWETWEEKIAKWLFNGDDRNVKRVWVRGRTVHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUN2</accession>
    <name>X0CUN2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Small EDRK-rich factor-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09889</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUN2"/>
    <dbReference type="HOGENOM" id="CLU_165034_2_0_1"/>
    <dbReference type="OrthoDB" id="18018at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="61" mass="6803" checksum="9E98E4ABE1AF107F" modified="2014-05-14" version="1">MSRGNQREKDRQANLDKQKKLKAGNNKSGTKMQQEKETAAEIMRRKQAASDARKAGTAGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUW5</accession>
    <name>X0CUW5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Autophagy-related protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">FOQG_03801</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="18">Homodimer. Dimerization requires the presence of ATG13. Forms a ternary complex with ATG13 and ATG17.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUW5"/>
    <dbReference type="SMR" id="X0CUW5"/>
    <dbReference type="eggNOG" id="KOG0595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006447_0_0_1"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14009">
        <property type="entry name" value="STKc_ATG1_ULK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000817">
        <property type="entry name" value="Serine/threonine-protein kinase ATG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048941">
        <property type="entry name" value="ATG1-like_MIT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022708">
        <property type="entry name" value="Atg1-like_tMIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF22">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12063">
        <property type="entry name" value="ATG1-like_MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21127">
        <property type="entry name" value="ATG1-like_MIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 22" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Protein kinase" evidence="21">
        <location>
            <begin position="25"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="347"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="435"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="511"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="778"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="860"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="922"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="357"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="516"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="787"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="866"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="923"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00060750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00065186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EXK95113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="952" mass="104618" checksum="89D21325014BFCB4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY52</accession>
    <name>X0CY52_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">3-methylcrotonyl-CoA carboxylase alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_01741</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY52"/>
    <dbReference type="eggNOG" id="KOG0238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_1_1"/>
    <dbReference type="OrthoDB" id="196847at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004485">
        <property type="term" value="F:methylcrotonoyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000003">
        <property type="entry name" value="Acetyl-CoA carboxylase biotin carboxyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000028">
        <property type="entry name" value="Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF33">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0092">Biotin</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="12">
        <location>
            <begin position="43"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="11">
        <location>
            <begin position="159"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="10">
        <location>
            <begin position="649"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK99096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="733" mass="80592" checksum="4CB4AF4FF5BBD823" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYY6</accession>
    <name>X0CYY6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA polymerase II transcription factor B subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_01914</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the TFB2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYY6"/>
    <dbReference type="eggNOG" id="KOG3471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027280_4_0_1"/>
    <dbReference type="OrthoDB" id="364513at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2610:FF:000001">
        <property type="entry name" value="General transcription factor IIH subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040662">
        <property type="entry name" value="Tfb2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004598">
        <property type="entry name" value="TFIIH_p52/Tfb2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00625">
        <property type="entry name" value="tfb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152">
        <property type="entry name" value="TFIIH, POLYPEPTIDE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03849">
        <property type="entry name" value="Tfb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18307">
        <property type="entry name" value="Tfb2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor Tfb2 C-terminal" evidence="10">
        <location>
            <begin position="425"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK99376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="496" mass="55554" checksum="BDCA1C81CBC42B73" modified="2014-05-14" version="1">MSVSPAPSLQLAEYLEKLPGTTFRKLYQQPSTAFAIFRRMLPHLAKTFVMRILYSPKPILLSDLDDWVKPSHKRQKDQALSILRVLHIVSITAPSKERPQEMQLTTNFKLSLRLALSGGGTHNSFGVPSTLQIPPEIDIAFLDRYARKKWEDILHFVVSSVGYKSAGESSGPNKSVKELLVAGRLVDRKASGSVGITQAGFTFLLQEANAQVWTLLLLWLEAMEVNKMAGLEATDMLSFLFVLASMELGRAYDTNALTEQRKNMLPSLVDFGLIYIPNHKRSMFFPTRLATTLTSSSNSLRSISDGVAAATAAALQPGQSGAPSGSVTAANTEQRGSVIIETNYRIYAYTQSTLQIAVLALFTKLAMRFPDMVAGRISRQSIRQAIQFGITAEQIISYLSAHAHDQMHRTAALNNKPVLPPTVVDQIRLWQLENERMKTTSGFLFKSFEDDREYKDIARFAEEVGVLVWKNDARQMFFASKHEQIRDYMKIRKKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZF3</accession>
    <name>X0CZF3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_00029</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZF3"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_27_2_1"/>
    <dbReference type="OrthoDB" id="5086884at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF11">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="438"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="42"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK99546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="532" mass="57996" checksum="641FEF950903F5DC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZM4</accession>
    <name>X0CZM4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZM4"/>
    <dbReference type="HOGENOM" id="CLU_156695_0_0_1"/>
    <dbReference type="OrthoDB" id="4966402at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="94" mass="11028" checksum="472DCE5AED16D25B" modified="2014-05-14" version="1">MCNWNIYLWKCNCWTLAIKEPCHSRRQQKTANCNQIQQVKKEWVHIQDKPCVNHRANASLYVNGPTAKWEDIESTAYQSAKSLAERGEFPDFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0D161</accession>
    <name>X0D161_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 19">Serine/threonine-protein kinase RIO1</fullName>
            <ecNumber evidence="4 19">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">FOQG_08254</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 22">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 19"/>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D161"/>
    <dbReference type="eggNOG" id="KOG2270">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018693_4_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05147">
        <property type="entry name" value="RIO1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000232">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000148">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051272">
        <property type="entry name" value="RIO-type_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017407">
        <property type="entry name" value="Ser/Thr_kinase_Rio1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45723">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038147">
        <property type="entry name" value="Ser/Thr_PK_RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 19 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 19 25" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 19 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 19" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="24">
        <location>
            <begin position="130"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="459"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="463"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="490"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="23">
        <location>
            <begin position="520"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="20">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="20">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="EXK88422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="543" mass="61877" checksum="0A9377B6FCF5166F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0D168</accession>
    <name>X0D168_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D168"/>
    <dbReference type="HOGENOM" id="CLU_1686627_0_0_1"/>
    <dbReference type="OrthoDB" id="5068927at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="156" mass="16739" checksum="AF5FA8B3DAA931D9" modified="2014-05-14" version="1">MSQSSNGHPSEGSASSPAMCMSSSPSVVSSSPTPANSESVPNRISSMASETPSANSQYKGYEESYDDRLPAAPSQMGMTDHGSRTYLSLGDDKLSDNVAIFGDRLHNLHDAINLVLERQNQEVNNPRSFVTDPVHWPDEAASAQHSAYSQSTPDHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2S6</accession>
    <name>X0D2S6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gluconolactonase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2S6"/>
    <dbReference type="eggNOG" id="ENOG502RZSA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036110_1_3_1"/>
    <dbReference type="OrthoDB" id="423498at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052988">
        <property type="entry name" value="Oryzine_lactonohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064:SF2">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="328" mass="35591" checksum="192BD1304F3B7E22" modified="2014-05-14" version="1">MSFKIYNEGANAIFDASSTVEVIHENEQYPFAHEAGVFIPEENALFITSNQFPDPTTGQKTIQISKVQLSPDGKFISCEEVNAPDVIMANGGVNYKGGVLFCSQGSLTAPGGLVFMQPIAPYRCAALVTSFYGRDFNSLNDVVVHSDGSVWFTDPIYGYEQGIRPAPQLRNQVYRYDPKDESVRVVADGFGRPNGISFSPDEKVVYITDTDWIHGDGTTDDTRARTIYAFDLSTISGEPFLTNKRVFAMADTGIPDGIKCDTKGNVYSGCGDGVNVWSPGGVLLGKILISGGVANFCFGRNGELFMLNERKIWRAQLASGVKGALLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0D323</accession>
    <name>X0D323_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Lid2 complex component snt2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_00799</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0955">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="336088at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048189">
        <property type="term" value="C:Lid2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036205">
        <property type="term" value="P:histone catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15497">
        <property type="entry name" value="PHD1_Snt2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.490:FF:000018">
        <property type="entry name" value="Lid2 complex component snt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000486">
        <property type="entry name" value="PHD finger and BAH domain (Snt2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000899">
        <property type="entry name" value="PHD finger and BAH domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000949">
        <property type="entry name" value="ELM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029617">
        <property type="entry name" value="Snt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47672">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SNT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47672:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SNT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51156">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BAH" evidence="9">
        <location>
            <begin position="205"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="360"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="ELM2" evidence="10">
        <location>
            <begin position="501"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="923"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="1031"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="419"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="556"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="768"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="854"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1215"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1332"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1390"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1002"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="430"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="859"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="882"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="892"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1215"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1394"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1447"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1510"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1534"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1548"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1570"/>
            <end position="1580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXL00802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1586" mass="175509" checksum="04A5E06AAE5ECD5E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3V6</accession>
    <name>X0D3V6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Chromatin structure-remodeling complex subunit RSC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_02853</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3V6"/>
    <dbReference type="eggNOG" id="KOG1827">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1742084at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04717">
        <property type="entry name" value="BAH_polybromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05522">
        <property type="entry name" value="Bromo_Rsc1_2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.490:FF:000015">
        <property type="entry name" value="Chromatin structure-remodeling complex subunit RSC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.10:FF:000048">
        <property type="entry name" value="RSC complex subunit (RSC1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037382">
        <property type="entry name" value="Rsc/polybromo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048047">
        <property type="entry name" value="RSC1/2_bromodom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062:SF21">
        <property type="entry name" value="CHROMATIN STRUCTURE-REMODELING COMPLEX SUBUNIT RSC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062">
        <property type="entry name" value="SWI/SNF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="87"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="289"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="BAH" evidence="11">
        <location>
            <begin position="401"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="182"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="587"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="705"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="843"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="900"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="30"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="200"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="594"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="843"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="900"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK97804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="919" mass="104043" checksum="6E504BA31D5588BF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0D487</accession>
    <name>X0D487_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyruvate dehydrogenase E2 component (Dihydrolipoamide acetyltransferase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_01010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D487"/>
    <dbReference type="eggNOG" id="KOG0557">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035825_2_0_1"/>
    <dbReference type="OrthoDB" id="202158at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF82">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE COMPLEX PROTEIN X COMPONENT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="34"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="6">
        <location>
            <begin position="170"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="124"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXL01192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="427" mass="45299" checksum="84C429B4B19269EE" modified="2014-05-14" version="1">MASLTAACRASARAVTSRSAIARGFTTSTRCLAAQNFTMPALSPTMTEGNIATWKVKEGEAFSAGDVLLEIETDKASMDVEAQDDGIMVKIMAGDGSKAVQVGSRIGVIAEAGDDINSLEIPADEQAKEQSKEQSSAQAPKESTAPSESNPVEKKSAKPTGNDTYEHKYPLLPSVGHLIKEKGISEADVKKIKGTGPHGRLLKGDILAYLGSINPETPAANEVNFNNLFHLDLSNIKVATKPAPPSKPVEEAKAEAPKAPVVENLEVSIPITLSKVVEVQTRIHETLGVFLPISTFVGRAAEVANDDLPPTKRAPTANELFDQVLGLDKIKAAKGSRGVYLPQISAVPPTSLLTPLSPTRKQTDIIDILAAPKKSAPKPATIQTVPGLSSGANVFTLVVPKAEEERAQIFLERCKVILEEEPGRLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8H5</accession>
    <name>X0D8H5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8H5"/>
    <dbReference type="eggNOG" id="ENOG502SN4A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030288_0_0_1"/>
    <dbReference type="OrthoDB" id="2142759at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="161"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="365" mass="42002" checksum="186D6CC42C3CE0E4" modified="2014-05-14" version="1">MGLLASNNHQLHLSHLEHRVSMPRSLSAVSSLEIRDLNRDQIRFYHPGYLKPLNLLFCLPRVDFNTTEGAFGVHYLTALTACQIVANNAFEKGYLARDERGKDRVSDDETILLQRDYWFFVEGDDRYAIVPSFRDWQFPHDRLPEWWSVPSSRTSLYAKRCAVTNTSYAFTWAHLIPREEQSWFSKNGMGLYGGGSHTIDDPHNILPLKADLYVCFDQSVFALIPKQSGQANGVEASSQYVLHVLDGREAEFTALYQNRPVETLVEGSREYLFARFAWSIFSFLKPFLTSGVGRRVVRFRLRASDDDAEEEHLISEMQNVFLDSRKLESLYGGGHRRKTVSLEDSYVDVEDEWDDEHPGRTEMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8R5</accession>
    <name>X0D8R5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8R5"/>
    <dbReference type="HOGENOM" id="CLU_094277_1_0_1"/>
    <dbReference type="OrthoDB" id="5106762at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="201" mass="21561" checksum="63758299590C73B6" modified="2014-05-14" version="1">MRLCITKIRQSLVPDVATATATTESTSSEATATSSSSGTTFTTDEATTTKAATTLEEATSSTEDADATPTIDPNYQPLVQQDPECLEPADGDHGAIDPGTQDDYAEDFSSQEPDGGWEAGADIQHSYKETSHGVVYEYKVNWAQDCITNGDTQDIRWPLGQAGDITAYSLMRGAFEKWNNGGIGGSIQAGRFVYTFNGYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8U5</accession>
    <name>X0D8U5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8U5"/>
    <dbReference type="HOGENOM" id="CLU_3191356_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="46" mass="5336" checksum="E7EBBB9323F1C23B" modified="2014-05-14" version="1">MATSKRQLRALKGKSLAGENLRFYVGPQYAVLQVPTKILYRMHRNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8W1</accession>
    <name>X0D8W1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8W1"/>
    <dbReference type="eggNOG" id="ENOG502SAHW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_2_6_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="46"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="279" mass="31497" checksum="52FA8DF6F229E85F" modified="2014-05-14" version="1">MPSTESQSDAAQRMYTERATNYEDSWHPDYSKRFMELVPIKSGDRVLDLACGTGLEAVIAARHVGDDGIVIGVDITEAMLSEASKKLDHDETLYRRIKLVRHSVTDLTGCPNVDRDSFDLILCSNAFVLFENPEEVVAHWRGYLKPGGRVAIDITHEYNLRSGLLLEKVARRLGMPFPSNRSWIKSKESFSEILESRGFVVEKVEALEKIVGLGSTYFGLDKADEQFDYVVNGPLTASIVTEELRVKGREYFKEEWHNAAVDGKVEVSDILYVYIARKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0DB15</accession>
    <name>X0DB15_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DB15"/>
    <dbReference type="HOGENOM" id="CLU_2263848_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL00729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="117" mass="13339" checksum="BB1DC4C382A90726" modified="2014-05-14" version="1">MSVTRLPAVGVGDGCTSMYVIPIAMTSQMDGVGYFTSTDERFVPFQQILRQRDGRWYGGLYASDDGARDDARADLRRGLHVLVLDLVWIEWLWLYALCEGAHFRVFRETKDLTLTCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0DF58</accession>
    <name>X0DF58_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Defect at low temperature protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DLT1</name>
        <name evidence="9" type="ORF">FOQG_05336</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Required for growth under high-pressure and low-temperature conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DLT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DF58"/>
    <dbReference type="eggNOG" id="ENOG502RAJJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022833_2_0_1"/>
    <dbReference type="OrthoDB" id="4096362at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038869">
        <property type="entry name" value="DLT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021:SF1">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="292"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="315"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK93147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="426" mass="47061" checksum="3C1A5EA4EC0C333B" modified="2014-05-14" version="1">MAPPVSHRRLVAAIVYRTLYLLLYVCLLGLLIATPADAIHRSFQNRQLYNIWIVIAAYVLAIVIISFVFITRLYINKTDLGSIPKGWVPIEKGDLRSTVYKVIALGLGQSASIAYESRPRLQTDNTAPDDETVEARVKLGFDGPSGPAEELVVVIPRKQPVWGDIEHYGWSSPNAPDLPNLEYTTVFSELPNLIEGKALTLAPPDPTSDTNPPLLDPDAVALLQRTANMSLRDYIVHLADLGVIEMDSTTVEFLSHYEYARFSNRPISNAQFKELMHLFAEILRAMEPLDPDILDEQDNTSSPSTDGDDDARSRLGTSRSNLAPSDASISSSTRIRRQPSTNTWNVYETAPNSVRSGFTGPGSISRRLSNNSLARSRRHYPMSQPSTSSLRSKSSASSGSVIRLATRHDSTDLPYVLSLRDTTASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0DLM1</accession>
    <name>X0DLM1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03872</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DLM1"/>
    <dbReference type="eggNOG" id="ENOG502S0EC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043835_1_1_1"/>
    <dbReference type="OrthoDB" id="2331100at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF8">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_6G00670)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937605" description="Extracellular serine-rich protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK95247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="40835" checksum="AEB3AB4986DE5359" modified="2014-05-14" version="1">MVSKSLLVLTAALATAWAQTTTDEPTATAEESSTGTSSGEAVTHTVNVGASGHKFTPNEVKAEVGDIIEWRFYPTDHWVIRGDYDNPCIPYEYIGVNRQGFSSGTQKVQAITDDGPRYRVRVNNTDPFFFYCGAPESCSKWKMMGVVNPSKNETIEGWLKNAEDVDMQLRPGDPWPKEGESTSTGATSEPTADNSDEDDESSGSGKKSLSTGAIAGIAVGGAAVLLLAGALLYLCGRRGGFDKAYRKSFRNSVPSAPPVVENPYSPHPSVADPWAAQKSPGLVAAPYGQSPPLSPHQSMPYGTHPGMVAQDGTPISYHEGYHQPPMAASPATTPKPHEQIAPVELPGSPDPNHSPLPAYNNNNNDGRGFSWNGDEQGYRPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0DMH7</accession>
    <name>X0DMH7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the complex I NDUFA12 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DMH7"/>
    <dbReference type="eggNOG" id="KOG3382">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110455_2_1_1"/>
    <dbReference type="OrthoDB" id="274641at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007763">
        <property type="entry name" value="NDUFA12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12910:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12910">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05071">
        <property type="entry name" value="NDUFA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="15447" checksum="7FB08819519A803D" modified="2014-05-14" version="1">MSTISRTLSNLRKVGIKDYFVQMLYIGDTKAGRLIGTDRAGNKFFENNEELPLRTRWVEYAKHDYDAAHIEPGWHAWISYSVDKPPTEDPLLQAGVRAFEPSRAIPNFTQTRGAFKTYNTSKSKISAWEPVAAPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DUB0</accession>
    <name>X0DUB0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-lysine N-methyltransferase EFM5</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFM5</name>
        <name evidence="7" type="ORF">FOQG_02861</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DUB0"/>
    <dbReference type="eggNOG" id="KOG3350">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074410_1_0_1"/>
    <dbReference type="OrthoDB" id="206354at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03187">
        <property type="entry name" value="Methyltr_EFM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019369">
        <property type="entry name" value="Efm5/EEF1AKMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041370">
        <property type="entry name" value="Mlase_EEF1AKMT1/ZCCHC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13200">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13200:SF0">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10237">
        <property type="entry name" value="N6-adenineMlase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK97817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="256" mass="28787" checksum="3F82B3948F528324" modified="2014-05-14" version="1">MSFDDEEPISLSSHALAALAEFHAEKDAHEKTFEKLRTGAAPRAGAGLGVVEPEDEDPVAEDADDQPLSMAAFTEDWNESQFWFLDETAFALADQLLDGASSSSIIGVVSTPSVFIALKNRLRFWPIEDRPKLVLLEHDHRFSVFPEFVFYDFQRPLQLPAHLKGSLDSVIIDPPFFSNDCQTKFALTGRWLVKPKSPRVIVCTGERMATIVDKLYRSLGVYATTFEPAHAGLSNHYYCYANFESSTWDWRSDESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DUB5</accession>
    <name>X0DUB5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rhomboid protease</fullName>
            <ecNumber evidence="4">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_02866</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S54 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="4"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DUB5"/>
    <dbReference type="eggNOG" id="KOG2632">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084816_0_0_1"/>
    <dbReference type="OrthoDB" id="10257275at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF1">
        <property type="entry name" value="RHOMBOID PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="12">
        <location>
            <begin position="61"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK97822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="267" mass="29652" checksum="7332C10A2EB7BF54" modified="2014-05-14" version="1">MRPRLQNFNALRARSYLTRLPLFTRLIIVAIVALSIASLQSVWNLREWGALIPEEISITNAYRLSTFPLIHLNIIHAILNLAALTPLMERFENEHGTLTSLALFFGPLTSIPAVMYVLIERYVFHVNHGVLGASMWVFTLLAMESIQTYKTNPHFVVGTVHIPTWTTPLIMCMVVRALVPGTSLLGHLCGIAIGYVAGFGYAKLLAPPEWGLRWVENRLNLLKILPHYVSIDKTTYGRFGVLPTTNRPGPSGSAATELVGTTQRLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0DW02</accession>
    <name>X0DW02_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_01303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL50 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DW02"/>
    <dbReference type="eggNOG" id="ENOG502S9FC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034472_2_1_1"/>
    <dbReference type="OrthoDB" id="6220758at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018305">
        <property type="entry name" value="Ribosomal_m50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10501">
        <property type="entry name" value="Ribosomal_L50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK98372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="380" mass="43051" checksum="F0FECDB3EE263A18" modified="2014-05-14" version="1">MPRIPRVGALASLPSTVVPVNRVPFVARVAFSTTPVHAAGRKAEWLRDKLWKGEAPGGDDPYQERVEPEQTSNLPEEALDLSNVDRRPYPVRTTRLVLPPSHSEAMTEKEVESVDTEYTPATSIDDLEEISPVKTWWDQPGHWGEESEFQGFGSANRVEDQAVMEIYVRQALVESLSYQQRGLLEEYAVKKWPFGDRAHLDRTLSVGIRFKDGKPLLSTHWSIVTEKLKNVRPGEVEEKVEISPEEAQQMVNALDPSWKTATLDDDHLKFAIRKRIYQLTGHFIPDVKVAAARTPQELITVALTFAKRGKKLAEVLEDQKALFALPNVKVHNRRVTPIDREVAVGRWKIIEEELQKRDLPVTGTGKYGKNKERDWLTGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0DW46</accession>
    <name>X0DW46_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DW46"/>
    <dbReference type="eggNOG" id="ENOG502RJ5W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085775_0_0_1"/>
    <dbReference type="OrthoDB" id="4840990at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="189" mass="21848" checksum="90CCCBE38B3B3494" modified="2014-05-14" version="1">MDHETTIIMNYPNIFGDRPKSRCPHCNFYPKHGENKVCEACESQMGKDDIEAFLGGAERNWCVYHLNREGFLPGRAALEDTMRARLIHEQRCVRLCCAEPKLPIYVHCEECREMSLCKGVPIAVAIKKIYELTHYDTFPDYDDDSFAVRVARAEASIYEEDWSWDCSLAKFVHPDRKSFKGNTSPEEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0DXW0</accession>
    <name>X0DXW0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DNA excision repair protein ERCC-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_01705</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPF family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DXW0"/>
    <dbReference type="eggNOG" id="KOG0442">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002265_2_0_1"/>
    <dbReference type="OrthoDB" id="361020at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000736">
        <property type="term" value="P:double-strand break repair via single-strand annealing, removal of nonhomologous ends"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20078">
        <property type="entry name" value="XPF_nuclease_XPF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000002">
        <property type="entry name" value="DNA repair endonuclease XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006167">
        <property type="entry name" value="XPF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047520">
        <property type="entry name" value="XPF_nuclease"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00596">
        <property type="entry name" value="rad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150:SF0">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="11">
        <location>
            <begin position="704"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="490"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK99012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="937" mass="105552" checksum="4C294EAD117C2AB1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0DYU5</accession>
    <name>X0DYU5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Piwi domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DYU5"/>
    <dbReference type="eggNOG" id="KOG1041">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004544_4_1_1"/>
    <dbReference type="OrthoDB" id="10252740at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Piwi" evidence="2">
        <location>
            <begin position="718"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1066" mass="117968" checksum="549D51CC9FF51DB1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0E154</accession>
    <name>X0E154_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E154"/>
    <dbReference type="eggNOG" id="ENOG502SP9C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057540_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXL00078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33110" checksum="217BFA1E253F4122" modified="2014-05-14" version="1">MGAKSGTALKFLQWFIRGIQFACAALILAIYSYFLATLHNHNLHISDTIRAVEGISGVAVLYTAAALVLVCCLAGRTLSSLLAIILDVAFIGAFIYVAVANKGGASSCTGYLDTPFGKGKAGNTAEGSDGFTALPSYRTACKLQSACLAVSIIAIIFFIFSIVIEVALARHHRKEKRFGPSPANDYTSGYGAKGGFLGRLFRRRKTAAAEEGHDLPEHTHPDQLDTYRQSHTTDRTAVNNYPDNTYNKYDNTGFSYQDTKYGRQDGYGQIHYPEPEYGVTQPPARQTENPNYRYEDGVYDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1M7</accession>
    <name>X0B1M7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_19583</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979966">
        <property type="protein sequence ID" value="EXK75651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1M7"/>
    <dbReference type="HOGENOM" id="CLU_1686679_0_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF237">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ATNE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK75651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18280" checksum="A90A983D1300A515" modified="2014-05-14" version="1" fragment="single">DFFHYLFHAIDPETGKGYSNDELLGESESLIIAGSDTSAISLAAAFFYLTRYPHVQDKLAKELKSTFPSVDDIRGGAALYSCQYLRAFIDETMRMSPPVPADLAREVQEGGIVVDGQYIPKGMKVSTASYCMHHNPDIYPEPFKFRPERWIVDENDECGVSSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2U9</accession>
    <name>X0B2U9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658718">
        <property type="protein sequence ID" value="EXK76455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2U9"/>
    <dbReference type="HOGENOM" id="CLU_1503517_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="167" mass="18942" checksum="7BA6F9DAA29EC707" modified="2014-05-14" version="1">MATASMTTTTTYTTTSPVTSASPPRVAVPSDLYDTPQPIYERYKAAREDWYTTQPQRARNDKAYRKARGLPTKYSKAAVKYALGHKEMGAQCILGIGQGRRDWTTEEIHAYTDFGEAENRLVEQAVERQLEQCYYLGDGIQAAQEEAIRDGQAQQLYYDNQNAYHQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3F7</accession>
    <name>X0B3F7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_18985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658742">
        <property type="protein sequence ID" value="EXK76266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3F7"/>
    <dbReference type="HOGENOM" id="CLU_041953_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15486">
        <property type="entry name" value="ZIP_Sip4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052783">
        <property type="entry name" value="Metabolic/Drug-Res_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="151"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK76266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="305" mass="34358" checksum="FBBE1B60DEC658EB" modified="2014-05-14" version="1">MHHTSKRANSSASIIHHYRHAPCTVGIDGRYKRVWNACGRCRMKKTKCDGEFPCKRCKDDGLVCTTAIRRKMKYKQLPRGYAEVLDNTQFTLIATIHKLYSMVLNNQPWELGEPDLNNHGQPVIHSIAQKLRCIRPQSDVELPVHSVFPENEASLSEPARQLEGQQDDNNQQMDDKDADYSASNRTERASLSPQSTDSTNDFGFAPTLPNIDAAAKCPSQSPSMPNFPAWFMTAKPQPSNLTMQFMQQPDALGNVDLRHQSRVGSEFNTISPHVLSCHNPAIIGNADERNHQRLRYEKGHILALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0B479</accession>
    <name>X0B479_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="2">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_18700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="2"/>
    <dbReference type="EMBL" id="KI979483">
        <property type="protein sequence ID" value="EXK76561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B479"/>
    <dbReference type="HOGENOM" id="CLU_005391_1_4_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK76561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="215" mass="23065" checksum="C21920EA4B4FD1E6" modified="2014-05-14" version="1">MVSLATQVGIPPGTLNCLIGGPDVGEALSSHMDIRKIRFTASIKAGKLIQVAAANSNLKSVTLELGGESPLIVFPNADLERALQPATMFLLMNGQGCALPTRLYVHETIADEFTAKLKNIVEEHGRNIGGDPTLPSTSSSLLYHRHQKEVVLSYIQTEIKEATLLTGGKPIGAKGCYVEPAIFVDPHPDAKVLREEIFGPVLVSLGFPLRTRSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5B3</accession>
    <name>X0B5B3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979396">
        <property type="protein sequence ID" value="EXK77305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5B3"/>
    <dbReference type="HOGENOM" id="CLU_028279_1_0_1"/>
    <dbReference type="OrthoDB" id="3774077at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="368" mass="41477" checksum="6E066447234BA8F7" modified="2014-05-14" version="1">MDERVLPNDPPWEADYPGSPGLPHPPASEIALLPGVTTFLQQTEPYERVAKEFRASWESVQHDDKHDVIAKAFYEAGDFVAWFAYFRIKRAAEQSASCTGKTDCRRLIDILQHADVFIQRQLATKVVAVFSDEQKEKIEKLHEKMSLSAARQPTADSNRLQILEAPQPYTTPSFNTDRVMIERSTIPTPNSFLTSYEQVIVNPPLNTAKKLLHKDLSNAIGTTQNPIPKGALLAAISMAFPPTGGKDDCQMVLEILEDKVQHFAKRWFKKRLESKDGLRCLVARDGSTIVPYPQFTLRGFQRRRRTDFGLVVSHAITTSPRYQDDEKHSRPYTDGVSMVVSAQANARAHVYLSLGLVEGIRIKDKLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5P4</accession>
    <name>X0B5P4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658607">
        <property type="protein sequence ID" value="EXK77445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5P4"/>
    <dbReference type="HOGENOM" id="CLU_3406452_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="30" mass="3389" checksum="4B19FBDF2C9E963A" modified="2014-05-14" version="1">MSLPDGHKGTVNLFHNSDEIRYGNFLAELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCK1</accession>
    <name>X0BCK1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658467">
        <property type="protein sequence ID" value="EXK79521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCK1"/>
    <dbReference type="HOGENOM" id="CLU_2941850_0_0_1"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="60" mass="6761" checksum="AE27C2FD760D3AC8" modified="2014-05-14" version="1">MGLIQACLNPLWAGFIGCCVTRDIKSAILAAGEWENPEDIERPEDVYNFLPRVWGVLIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDQ6</accession>
    <name>X0BDQ6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_15208</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS27 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979338">
        <property type="protein sequence ID" value="EXK80265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDQ6"/>
    <dbReference type="SMR" id="X0BDQ6"/>
    <dbReference type="eggNOG" id="KOG1779">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130128_3_0_1"/>
    <dbReference type="OrthoDB" id="5567124at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.100:FF:000001">
        <property type="entry name" value="40S ribosomal protein S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.100">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00371">
        <property type="entry name" value="Ribosomal_eS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000592">
        <property type="entry name" value="Ribosomal_eS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023407">
        <property type="entry name" value="Ribosomal_eS27_Zn-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11594">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01667">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK80265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="82" mass="8854" checksum="345CE19F6FBBC759" modified="2014-05-14" version="1">MVLAVDLLNPSPAAEAKKHKLKTLVPAPRSFFMDVKCPGCFTITTVFSHAQTVVICQGCTTVLCQPTGGKARLTEGCSFRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE79</accession>
    <name>X0BE79_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658685">
        <property type="protein sequence ID" value="EXK76769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE79"/>
    <dbReference type="HOGENOM" id="CLU_1740656_0_0_1"/>
    <dbReference type="OrthoDB" id="5079016at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936266" evidence="1">
        <location>
            <begin position="18"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="148" mass="15642" checksum="EF032E69CEF0923A" modified="2014-05-14" version="1">MKPVLVSLGWMAMLASATPILSDPATTLPVKGDGTLDRRAVVASDSRDTAASNTLEKRAIRKMVLPNRIGSVIQNIGVIVVKAIVDAAGELISQITNNSPYTYQVSLREHDVAIDAAIVNVAAHHTIEYDKLGGIKPGAIISVNTQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEF7</accession>
    <name>X0BEF7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_14979</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979337">
        <property type="protein sequence ID" value="EXK80545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEF7"/>
    <dbReference type="eggNOG" id="ENOG502SHYH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044876_0_0_1"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF4">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="4">
        <location>
            <begin position="6"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK80545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="294" mass="32617" checksum="98F4338EDCB57A90" modified="2014-05-14" version="1">MSSIVAVAGGSRGLGRAIVEAILADNKHHVFILSRQTSEEGEKEIGARFLQVDYSDIDNIKTLLEHHKIDTVISALSAKAIGLYEMNLAVASEKSNVTTSSPLPFGPPKAAVMDFLKTTDLEYSAWHTGFFIDYYVSPPLKSPLDHWTVFIDIANRTAALPGSGDVPVAMSYTMDVAKFVAGSLSLSKWERETLIYNDKLTMNQYVQVVEEVRGEKIQVTYDSLDLLKSGKITELPSHPPMYEFVSKDVIQSFLAAFGILFETGEFDLREGYRIQDGLPSLKLQNFRDLLTQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEQ0</accession>
    <name>X0BEQ0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979429">
        <property type="protein sequence ID" value="EXK76964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEQ0"/>
    <dbReference type="HOGENOM" id="CLU_071639_0_0_1"/>
    <dbReference type="OrthoDB" id="5305386at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="226" mass="25440" checksum="E509456CD6A1335D" modified="2014-05-14" version="1">MAPIGDFAQGDEIEVDDDILDQICQGISFLWTMLVVEMPLVSKEEHLERLQSLPVAVGSYIFTLRFNNGLLPNADRIRASEVKPDPEKPFRAADHRIGDLFLVDYAAGVTQTVCNFGRRSTLGWKGDAPHNVEPRNSQGEGSSNGVKYFAFDQAAFVANEREIALSCASVPLRCRNESLKRHQPQRMAAQECGMLHLPNHQLRSSNRNERLILYTVSYDSEFEERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF13</accession>
    <name>X0BF13_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658437">
        <property type="protein sequence ID" value="EXK80710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF13"/>
    <dbReference type="HOGENOM" id="CLU_1525228_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="176" mass="18980" checksum="7D6FB3FCCA5731C3" modified="2014-05-14" version="1">MYLQDPKVTPFRIDKSGAPPEGVCLRVTWEAKRSWQGSKAQANASQTGGSITPIAQGPSGLYVQWPHTCAATGAHLREFCKMNATTNARSNQYLAPSLTPNGKSAARFWNRRSAPARSPSIFSAQGMAISLAVSTSDSMQLQGPLAQLTSSHPDLQLEELPAPPPKRRDPSTCRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFE6</accession>
    <name>X0BFE6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658434">
        <property type="protein sequence ID" value="EXK80865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFE6"/>
    <dbReference type="HOGENOM" id="CLU_906267_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="307" mass="35603" checksum="80B42526AD5D9DA8" modified="2014-05-14" version="1">MATVRKIVKDKDVVNYLLKEIVSTLEEDISRLENEQCECVQRLVTNNGTLASKKEMLKEKKTQLEDLEQGSHEVQAIRQESHDGITEKPYENDVPVGCKLLKSHPDPEEHQDTCSKTSWEEDEPDTYVARGYAPEDDEFHFETWSDTESCSGGSITKYDWRLAVVKTRLYTSHINVTQYWTWAGNTQCFQHQVLKDVKPAKWGLFREEINFHVNLAEIEEMEYSIEALRVRIIMKEDAGKLAADGKPRGDVMVSFPRARTMRRFLFFCREKGMKIAKREPEQLNNLWDSMVSEQLPGRGDSHQQLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFL9</accession>
    <name>X0BFL9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658627">
        <property type="protein sequence ID" value="EXK77254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFL9"/>
    <dbReference type="HOGENOM" id="CLU_1326407_0_0_1"/>
    <dbReference type="OrthoDB" id="5040651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="204" mass="22645" checksum="211F49E42AD803A6" modified="2014-05-14" version="1">MHKVDWKDSTPERRLAIMNLVEKYPHIPHPAGDDTAEPPSSLVPPSQQPDIPGMSSDVFTQPAWNASSKTRKACREGCPPDQFQYQEQGIPSTPRLKRIVARLPTSSPPDVRETQQIPALTSSVPQTVTPTTSSHVYPVLSPPPMSSNRATTELNKLLSELEEARNRFHRLLPQTVDAQAEMERCETKVKQFYLANGPGAVSNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BG41</accession>
    <name>X0BG41_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658429">
        <property type="protein sequence ID" value="EXK81130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BG41"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_138_0_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="22"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="2">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="409" mass="46425" checksum="2AB41B95943B6C9B" modified="2014-05-14" version="1">MRLLNTRTRSFEEFYGSKVPKYAILSHTWGQEEVTFLDWADPTSVMQKSGFTKIIEACEQARNDDYSYIWVDTNCIDKSSSAELTEAINSMFAWYSKADICYAYLSDVPTFKPLSYAKEFRQSRWFKRGWTLQELLAPDCVVFYAADWSRIGTRSTLVRDIVEATGIGIRYLSPDPKTATATHEDWSEVRSPVCHEASIAERMSWLSRRETTRIEDMAYCMLGIFGIHMPLVYGEGPRAFLRLQEEILKTSDDHSLFCWSWAMSENQGSLLAPRPHSFLEASPYQRHTIGVKPSPYAIANSGLSIRLPLIQCWSSCIAVLNVTLGAGTHVGIALRKEALTGVFTRASYPDVPIPLTTAMDYRGLPLTDMFIPARRTDSERTRPPSLTSQTQLTFELFHQTSSPRMTAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BG92</accession>
    <name>X0BG92_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658435">
        <property type="protein sequence ID" value="EXK80831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BG92"/>
    <dbReference type="HOGENOM" id="CLU_030130_2_0_1"/>
    <dbReference type="OrthoDB" id="412018at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07197">
        <property type="entry name" value="nitrilase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050345">
        <property type="entry name" value="Aliph_Amidase/BUP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674:SF16">
        <property type="entry name" value="CARBON-NITROGEN FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G02350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674">
        <property type="entry name" value="NITRILASE C965.09-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="282" mass="31328" checksum="3F4239D23C9258F7" modified="2014-05-14" version="1">MAPVYKIALCQFNPKVAKVAENFALAESYLRLAADKGCHLAVLPEFHLTSWEPSHPDFIAAMKESMSCLAKYQALARELDINIIPGTLCESYTGERGEEELKNVAYFLAAGTGDICGSYQKKNLWHPERPYLTPGRDLHLAFGTPLKDINGKSLRAGLLIYWDLTFPEGFRALVQDGADLIIIPAYWSTAGGEDIRQLNGDAETVFLDSVLTARAFENNAVVVFCNAGGLIRVILPILGSLGSIPPGEDKVEVFDVDLVVLWVAEERYKIRKDMQSLEWQYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH17</accession>
    <name>X0BH17_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_14093</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH17"/>
    <dbReference type="HOGENOM" id="CLU_010915_0_0_1"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051637">
        <property type="entry name" value="Ank_repeat_dom-contain_49"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180:SF45">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE TANKYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="521"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="148"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK81455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1018" mass="115679" checksum="39AD493B07ACEB53" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH28</accession>
    <name>X0BH28_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658577">
        <property type="protein sequence ID" value="EXK77749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH28"/>
    <dbReference type="HOGENOM" id="CLU_045417_1_1_1"/>
    <dbReference type="OrthoDB" id="3928699at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="271"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="369" mass="40994" checksum="10279DC3BB7FF116" modified="2014-05-14" version="1">MSSIRIQNTTAVIEWDVDDTTRSLATPDPINSTIQFTLRLDAPTTKGQRGALFEVMVPVRFKDRGKHASIYLRLSPLFISSFAFTIKTEPSDDIKTTFSNAVTCLDLTLEKPIAFLAPRYVQMPVTAARLRSGAVLDALRELSRARRMRIYVSEEVITAAQLTLIQDAISQRTLEPLSGPDTDISRMFGGLGGKPVHLSLPETVPALPTYDDAAALPPPAPPLERKRPRSDSDNDGDGDKGSSRLWTKVLQLESIIMTYVEKPRAQVNVGVEELRTENTQLRERVACLEDKVLTLQNKNEELERDMAILEQANKGRDEEEDTQLISISEDIESLASRVDWIERGKDDEAFADKIKGVIFDELAARVAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHD8</accession>
    <name>X0BHD8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chromosome segregation in meiosis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in the control of DNA replication and the maintenance of replication fork stability.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CSM3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658428">
        <property type="protein sequence ID" value="EXK81216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHD8"/>
    <dbReference type="eggNOG" id="KOG3004">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036204_1_0_1"/>
    <dbReference type="OrthoDB" id="437078at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031298">
        <property type="term" value="C:replication fork protection complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012923">
        <property type="entry name" value="Csm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040038">
        <property type="entry name" value="TIPIN/Csm3/Swi3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13220">
        <property type="entry name" value="TIMELESS INTERACTING-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13220:SF11">
        <property type="entry name" value="TIMELESS-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07962">
        <property type="entry name" value="Swi3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0236">DNA replication inhibitor</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromosome segregation in meiosis protein 3" evidence="9">
        <location>
            <begin position="62"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="142"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="291" mass="32447" checksum="9EB2E4CFF054ACD3" modified="2014-05-14" version="1">MPTLDSDPANGLDNYDVDDFSDDPFASPPPEAANKKRKEPDSGLGIDEEVDVKKRARVPNVKLDEERLLGPKGIPKLRQRAKDLKIKGKGHEFSDASRLLSFYQLWLDDLFPKAKFLDALTMVEKAGHKKRVMIARNDYINESKPKDRTADDEEEDDMFGENDASKPTEQEGTRPKTPEQDTGVPDDDDLYDATPRAAQRNSGPIVPIRNDVPEDDDFEALIAEAASHDAAPRARTNPTPAEPDDDDLDALMAEAESHDQTSKEKGQGPKDKETNNFDDEEAAMQEMDGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHL4</accession>
    <name>X0BHL4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_17338</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658555">
        <property type="protein sequence ID" value="EXK77974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHL4"/>
    <dbReference type="HOGENOM" id="CLU_1069749_0_0_1"/>
    <dbReference type="OrthoDB" id="295274at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002112">
        <property type="entry name" value="Leuzip_Jun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00043">
        <property type="entry name" value="LEUZIPPRJUN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="171"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="100"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK77974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="260" mass="29553" checksum="F1C0C2FF081B6875" modified="2014-05-14" version="1">MLVGYTADEAIGDDLTVYGAAIPSYPQWELSESMNPPAFLGAFHNEVGITTLSRQDYLPQDQLLFYGESSSGDHWVNIYSTVKNQTLSPDRLVTVADEPLSTLTPSLQSSQELPNKPGRKRKTQLSGRAASESARRNAKGDNNTDDQRRRGIVADGNGINVSSGMTNRKQHIKHKRIQERNRIAADKCRMRKREHFSRLQFDEQATEQRHRELSSCMNDLNEEILYLKMQLLQHTSCNCTLIQHYIKNEAQRYTDALGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHQ2</accession>
    <name>X0BHQ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979333">
        <property type="protein sequence ID" value="EXK81361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHQ2"/>
    <dbReference type="HOGENOM" id="CLU_004758_0_0_1"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="798"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="977" mass="110170" checksum="D75C02146CCC7853" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHZ0</accession>
    <name>X0BHZ0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chromatin modification-related protein EAF7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_14185</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF7 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979332">
        <property type="protein sequence ID" value="EXK81451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHZ0"/>
    <dbReference type="eggNOG" id="KOG4051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050564_0_0_1"/>
    <dbReference type="OrthoDB" id="5595141at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012423">
        <property type="entry name" value="Eaf7/MRGBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581">
        <property type="entry name" value="MRG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581:SF5">
        <property type="entry name" value="MRG_MORF4L-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07904">
        <property type="entry name" value="Eaf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="150"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="229"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK81451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="32800" checksum="4535E136DE026167" modified="2014-05-14" version="1">MAPRKRARASTQTVATPTPARDDDAMDVDTPQTGDNEGSSETKEQQPDNNYNDLWTDDQVASLFKGVIRWKPAGMHKHFRMIAISEHLRNHGFDPDFYQHTRIPYIWQKLRTYYNLEVIDERENFDDDESEYNEFSLPRAQFFDAMMARAAADPSEAPTSPPQLELSPAPSPAKKRKRGDTKTRGTSVEDTEEGTDAPSPAPKSKRGASRQKKKATPAKAEKQEKAETTEEEEEEEEEGESEEEESESSSSEEEESAEESETQVSKSTRGAKKGQKVKTTKAKARPKRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJT5</accession>
    <name>X0BJT5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_16650</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658508">
        <property type="protein sequence ID" value="EXK78689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJT5"/>
    <dbReference type="eggNOG" id="KOG1414">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_816467_0_0_1"/>
    <dbReference type="OrthoDB" id="295274at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="134"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK78689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="338" mass="37814" checksum="6FB192F0D0C37CDE" modified="2014-05-14" version="1">MSRNHMTYQPTPSQRGASSFFKEAIDASLVPMEVGVGPTYIALPTQPAEFKKLGGSEILQNILPSVMGDKKLNRRAHNRRQSQANEALFESSASGQAAESPKLRKRGRKPKKQPKEQKVAGQLEELDDDDLPKDPRRRRVLERNRMAANKCRLRKRDKALALASREEAMEDRNRYLMTCFDSLTVEIYYLKTQLLQHTDCNCVLIQKYIANEAKKCADGMLAPSAFDTHGSSWSPDHRRPSDANTAGELSMRGLEAGSSPPIWTNSFQQEPGVSKISDDIFAMGLEPIQKATMPSDSIVSTQPVQTFSLTKCELGLYLNVGPQEHQADEVAWGSYWQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BN93</accession>
    <name>X0BN93_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_12170</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BN93"/>
    <dbReference type="ESTHER" id="fusof-f9g972">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_7_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152111" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="23"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK83650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="534" mass="58735" checksum="0864E80A7CD69191" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRL0</accession>
    <name>X0BRL0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11306</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRL0"/>
    <dbReference type="HOGENOM" id="CLU_175710_0_0_1"/>
    <dbReference type="OrthoDB" id="5061983at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="85" mass="9641" checksum="1B4A8D1E6536C8E5" modified="2014-05-14" version="1">MPIVPTATFVGIKGQDYHEFVISKKNVKDEWKLKDALNIIFDGDGTPREYACCQVNLEDYRITSWEKKDVLSELSGMEDTGVVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSV2</accession>
    <name>X0BSV2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_13654</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK82013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSV2"/>
    <dbReference type="eggNOG" id="KOG3857">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007207_0_2_1"/>
    <dbReference type="OrthoDB" id="339764at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08192">
        <property type="entry name" value="MAR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF107">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="3">
        <location>
            <begin position="29"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="4">
        <location>
            <begin position="213"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK82013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="413" mass="45118" checksum="9E6F9C2166154C1A" modified="2014-05-14" version="1">MTDSLKPYRIPQLEGGHRPGSDAILNSHSKDDILSALKEWNSQRVLLVHSKALAKNTPVIADLKEALGDRLITVKEGVGSHSPYEDVIDIAHRITEHKTDCVISVGSGSYSDACKVARLMSATLPAGFGEKDMEDLLDQEKGVAPQDKMKRAEGVKLILVPTSLSAGEWNHTASCTNSAGKKQHFSLQDGGAPDLILMDPWVARTSPEKLWLSSGIRAVDHCIETLCNPECKKYPDVQEWCEKALRDLAKGLVEYKEGLGRGKEGEDELVHGVSKCQAGSRMALMGFIIYRVNMGASHAIGHQLGSVGKVMHGITSCIMLPPVLRYTKARNPEAQAKIVKIFNETLGWEETEAGDCVARLVKVIGLPSTLREVGVTSDGQIEQIIDKTMTDVMFSFGKVLTREEVSEIVYSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BT80</accession>
    <name>X0BT80_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10771</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BT80"/>
    <dbReference type="eggNOG" id="ENOG502RFEM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019313_0_0_1"/>
    <dbReference type="OrthoDB" id="5213892at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF26">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="554" mass="61999" checksum="9F2A8B769231709A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUG3</accession>
    <name>X0BUG3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_10609</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUG3"/>
    <dbReference type="eggNOG" id="ENOG502QVGN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_10_1_1"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938866" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="18"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="59"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK85546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="497" mass="54575" checksum="3A53E25586C13352" modified="2014-05-14" version="1">MMVSFLLICLQAALALAASTSPANKSTALNNCLASKKVPYIRPSSPQWTQEVRPYNLRLAYTPAAIALPTTVDHVQDAVKCGNQYQVRVSAKSGGHSYGSFGYGGENGHLVIVLDSMDQVTLNKYMSCNIQAGARLGHVASELYKLGQRAIPHGSCPGVGIAGHALHGGYGFASRTYGLTLDTFIGATVILANGTRTYAADGEGGDNQLMWALRGAGSSYGIVVELDFQTIKAPDTVTPFNIELDWNENQAVEGLIAFQKFAVTAPKQLNMQIYIGPSGQTIQGVYYGTRATLNTALKPFLGDIKAQISASSIGDWIEGLKAYANGQNLDQRRPYNQHSTFYSTSLMTKALTRSQVKSFVRTLFDNIKDSDARHSWYILIDLFGGPNSAITTAGSTNSAFPHRDKLLLFQFSDHGNYASHANNGFTLLKRFRESITKTMDDSDWGMYANYLDTQLENREAVEQYYELSLGRLRELKRAYDRNDMFWNPQGIRPATRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUL5</accession>
    <name>X0BUL5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10394</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUL5"/>
    <dbReference type="eggNOG" id="ENOG502SJ3K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008719_4_1_1"/>
    <dbReference type="OrthoDB" id="5319341at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="82"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="199"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="320"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="665" mass="74607" checksum="C577E3D1EA130663" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUX2</accession>
    <name>X0BUX2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUX2"/>
    <dbReference type="HOGENOM" id="CLU_022883_1_0_1"/>
    <dbReference type="OrthoDB" id="3061561at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043:SF8">
        <property type="entry name" value="DUF4220 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="438"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="486" mass="55789" checksum="0231AAA3E4672A61" modified="2014-05-14" version="1">MTSNQTEYVGWTPSPDGRGTYDIIVTCLVTTFLCCWTSVYPNIPAQGDGFWSSIRDKLGLACLGLLGPEFIIVLAIGQKSSARRSVAKFKQAGYTKWTITHGFFADMGGFVLSANGLERPIPLNAEQLFYLIKKSYVDYPKISDDELKDRNKSDGLARLITLWQGTWFVITFIARLIQGLHVTTMELTAVSFVIILFGTAWCWKDKPSDVGTTITVPCLTTMEDILIREGRSPDQPYYQTPLDFISRDETALNLAWQYYNELSRKILFSPFSRRVKRVPWDRNPGDIFLRMDFDLELVGVAFIFVFSAVFLGAWNFSFPSNVERDFWRVASVYMLAYGMFGALWMELCMWIFIPQYRLAEGLELSLVEQDLDQRPHPVRNWHYRFQNWRRSRFSKIRGTRDSDGEGLTSQQPKKGIFAFLSRSYNISQGNDPHLGVQVGFLIVTSFLCASYCVFRVFIFVEDFIGLRALPQSAYQTVEWAEFIPHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV08</accession>
    <name>X0BV08_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV08"/>
    <dbReference type="HOGENOM" id="CLU_2922738_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="61" mass="6801" checksum="0CC3C082E8D90B4C" modified="2014-05-14" version="1">MEPYRQPTTETTGDNSLKIFVQAIGNLDTDLYVAAQKIARDGTQIQWYNVTQVIEASAMHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV46</accession>
    <name>X0BV46_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_13244</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV46"/>
    <dbReference type="eggNOG" id="ENOG502SY1T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057733_0_0_1"/>
    <dbReference type="OrthoDB" id="4158815at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="172"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="259"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="177"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="34700" checksum="D207C7726A677FEB" modified="2014-05-14" version="1">MPTLEPATDLDSNVWYQLSELAVDDNDGDFKSMLQPTAPGGDLRVGAANKQSYWQFQKIGNKPGRYQLRCSDTTVKKQLSVCYRPEVINEKLRTRPCLMPIEDSEMQQWDISLWDSDTYRLTNVKNGTKWNLDCIPNGPVILSSDLEGEQPRQHWLMSSVGQVNNEMYSTVYTAPPESTGESTATAGTTGSDSTAATATSDSSSDPSNNSSESNDSGSGSSGLSTGAVAGISVGVTLGVVALALAAFFFWRRNKRKYQVAGISSPDSPGKPDSSPMAVSPNPAYSSVYSAEKNNASPAAEMMHEQRPVELSTGQHQRHELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWX6</accession>
    <name>X0BWX6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_12295</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWX6"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_4_1"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF164">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="53"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK83433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="537" mass="58566" checksum="D091FB13391BD446" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXG6</accession>
    <name>X0BXG6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_12148</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXG6"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="531"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="64"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK83628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="567" mass="60722" checksum="A34EA8332F94756C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYD1</accession>
    <name>X0BYD1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycogen debranching enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYD1"/>
    <dbReference type="eggNOG" id="ENOG502QV7E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012888_0_0_1"/>
    <dbReference type="OrthoDB" id="2591256at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936076" description="Glycogen debranching enzyme" evidence="1">
        <location>
            <begin position="20"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="736" mass="80808" checksum="12BAF252611FF1F9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ33</accession>
    <name>X0BZ33_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_09243</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ33"/>
    <dbReference type="eggNOG" id="KOG3030">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021458_0_1_1"/>
    <dbReference type="OrthoDB" id="10030083at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF84">
        <property type="entry name" value="PHOSPHATIDIC ACID PHOSPHATASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="120"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="329"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK87445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="369" mass="41015" checksum="A17546D964515F35" modified="2014-05-14" version="1">MPLLPRVNSAVANRSQSKKQKFKTFMRQWFLVNWRDLLAMAVVGAVAFGIYHSPVIITRTFPVTFDATSGDIVYPQWAYPDRGWILPSWLSGLISIAIPIITYIVAQFRIKSAWDASNAIIGTNWSVILASLFQVTLKQLVGGFRPYFLDVCMPDISLAKTHNKTGLNGVGFYQIMYTTEICTQPDKSRIQNAITSFPSGHTTAAFAGFGFLFLWLNAKLKVWADHKPAFWKLFLTFLPLLGAVLIAGSLTIDAAHNWYDILGGGFIGTIMAFASYRSTYASVWDWRFNHLPLQETEAFRYGFDGDLDYAAQTLSMAAGWGGKKVRLPESASAPAISSESTLRSGAEEIENLDANTRRKRRGPVGDEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZY1</accession>
    <name>X0BZY1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11508</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZY1"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF39">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="6">
        <location>
            <begin position="37"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK84493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="576" mass="63560" checksum="EFD6CCFE08E9D07E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0C089</accession>
    <name>X0C089_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C089"/>
    <dbReference type="eggNOG" id="KOG0896">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063065_4_0_1"/>
    <dbReference type="OrthoDB" id="6508832at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006301">
        <property type="term" value="P:DNA damage tolerance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23807">
        <property type="entry name" value="UEV_UBE2V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000026">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="6"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="140" mass="15799" checksum="672F100DFF6532BC" modified="2014-05-14" version="1">MSAKVPRNFRLLEELEKGEKGLGAEACSYGLEDPEDLLMSKWNGTILGPPHSVHENRIYSVKMHCGPEYPDKPPSIQFISQVNLPCVNPNNGIVDPNQLPCLAQWKRENTMETVLIELRRYMASSQNKKIAQPPEGSTYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0M0</accession>
    <name>X0C0M0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_08829</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21. Interacts with preproteins in transit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Mitochondrion inner membrane</location>
            <topology evidence="1 15">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the TIM50 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0M0"/>
    <dbReference type="eggNOG" id="KOG2832">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023309_0_0_1"/>
    <dbReference type="OrthoDB" id="287041at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000019">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 15" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10 15" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FCP1 homology" evidence="17">
        <location>
            <begin position="229"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="44"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00063960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK87975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="521" mass="59385" checksum="EAABE88BF2D110A7" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2G6</accession>
    <name>X0C2G6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658657">
        <property type="protein sequence ID" value="EXK76982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2G6"/>
    <dbReference type="HOGENOM" id="CLU_1875544_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="2">
        <location>
            <begin position="37"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="15466" checksum="7236BDCD0E93EBF1" modified="2014-05-14" version="1">MCFRERNVCESNLTHQHRRRPLAQPNKPIQGSTGERKLDIGFVKNTSAGKDSRCRWSQILVPGKLKSNPSTDKASMAWLDLGRHAREVLVAQNTRRFVLSFTICGSLMRVWAFDRLRGIALELSLTLRKMGVSLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C340</accession>
    <name>X0C340_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C340"/>
    <dbReference type="HOGENOM" id="CLU_3125134_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="50" mass="5559" checksum="48D0FD65545D137B" modified="2014-05-14" version="1">MGSGRSSGSWGSKSSSKSLPECKEHKCHKPVARFRSKGYSVHCDKREHNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C363</accession>
    <name>X0C363_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C363"/>
    <dbReference type="HOGENOM" id="CLU_115468_0_0_1"/>
    <dbReference type="OrthoDB" id="3660917at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="129" mass="14514" checksum="5BDB82C21659AA71" modified="2014-05-14" version="1">MVSAEYTVEIPDDAVWITNWDELHAAPRFEGVLLPKYGGFVIEVDEKIVLATDERMSKEVFDLLTDLEKDDPQPEEKQTTPNKRDAKIRGYGNRCSHPPCFGPGLCSQYSHCHVCSGLTGVVFKRGRCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C403</accession>
    <name>X0C403_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cortactin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_07852</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C403"/>
    <dbReference type="eggNOG" id="KOG3655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013085_2_0_1"/>
    <dbReference type="OrthoDB" id="5971719at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11281">
        <property type="entry name" value="ADF_drebrin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11962">
        <property type="entry name" value="SH3_Abp1_fungi_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11961">
        <property type="entry name" value="SH3_Abp1_fungi_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000242">
        <property type="entry name" value="Actin binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000273">
        <property type="entry name" value="Actin binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000045">
        <property type="entry name" value="Actin binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035719">
        <property type="entry name" value="Abp1_fungi_SH3_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035718">
        <property type="entry name" value="Abp1_fungi_SH3_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF25">
        <property type="entry name" value="DREBRIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="ADF-H" evidence="5">
        <location>
            <begin position="5"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="666"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="760"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="309"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="638"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="728"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="425"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="568"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="598"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="641"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="656"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK89130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="818" mass="85457" checksum="35BC392AA75AC2E9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4P7</accession>
    <name>X0C4P7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_07991</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Non-catalytic component of the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4P7"/>
    <dbReference type="MEROPS" id="T01.A13"/>
    <dbReference type="eggNOG" id="KOG0185">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10248542at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03760">
        <property type="entry name" value="proteasome_beta_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000014">
        <property type="entry name" value="Proteasome subunit beta type-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016295">
        <property type="entry name" value="Proteasome_beta4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF6">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001213">
        <property type="entry name" value="Psome_endopept_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK89380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="261" mass="29096" checksum="9F1CE41F7FCAEE54" modified="2014-05-14" version="1">MDHRPQAWGRPRDDVYGAYDASFMTDNGPKQNTQQPIVTGTSVIAVKFKDGVVMAADNLASYGSLARFTDVKRLRSFAESSVVGFSGDISDMQYLDRHLIDLSLDEAYTSPDAPRLNAANLHRYLAKLLYRRRSKFDPLWNHLLVAGLDDDDKPFLAAADLLGSTYSAPSLATGFGSMLAQPIMRRHVPDEEAAQNLEKEEAIKIIKECMKVLYYRDARSLDSYSMAVVTKEGVELTDGLQLEAQSWAFAERIRGYGTQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6V0</accession>
    <name>X0C6V0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658517">
        <property type="protein sequence ID" value="EXK78457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6V0"/>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07105">
        <property type="entry name" value="ALDH_SaliADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF6">
        <property type="entry name" value="CYTOPLASMIC ALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="2">
        <location>
            <begin position="44"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="491" mass="53446" checksum="768787CCE06F85B9" modified="2014-05-14" version="1">MLKSLIRRTGHINQGALPLSRGHRSLSTNFSVPLIINGQQVHTSESFPVTSPLTNKEIWSFSCAKDEHIQKAVQSAHSAFKDWSKTKASSRRDIFLKAADIMDRRRAELGEYMHHEIGANKFYQDFILGVTIEGLRDTAGGIAGAMTGAAPESIHQVVLGIAPWNAPYNLGLRSVLFALATGNTTILKGSEYTPRCYWAIYDVLREAGLPDGCLNLLFHSPAEAASTIDSLVSHPLVKKINFTGSTGVGRIISATAGKHLKPVLMELGGKASAIVLKDADLEQAARHCVQGAFLNAGQICMSTERIIVHESIASEFQDLLGHVIRKNFGTAHDTPAVVTSASASRNRDLISDAISKGAHQVKIFGDEHAHETETKMRPVVLGNVKKNMDIYSQESFGPSVSLFTFQTHREALDLANNTEYGLTASIFSKDLKAAFDLANDLESGAVHINSMTVHDESSLPHGGVKDSGFGRFNGSQGLDEFLYYKTVTWME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C738</accession>
    <name>X0C738_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cullin 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09493</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the cullin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C738"/>
    <dbReference type="eggNOG" id="KOG2166">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004747_7_1_1"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000014">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000001">
        <property type="entry name" value="Cullin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000002">
        <property type="entry name" value="cullin-3 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000061">
        <property type="entry name" value="Related to cullulin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000036">
        <property type="entry name" value="SCF ubiquitin ligase subunit CulC, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.130:FF:000011">
        <property type="entry name" value="SCF ubiquitin ligase subunit CulC, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cullin family profile" evidence="6">
        <location>
            <begin position="449"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK86629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="839" mass="96115" checksum="E8E3EE0C0B235B9C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7J1</accession>
    <name>X0C7J1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16666</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658510">
        <property type="protein sequence ID" value="EXK78662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7J1"/>
    <dbReference type="HOGENOM" id="CLU_3399447_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="31" mass="3770" checksum="42C1896EB0F03261" modified="2014-05-14" version="1">MSDKRIYYLFKPGQVAYANFIYCSFPSHPYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8D7</accession>
    <name>X0C8D7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_16386</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979352">
        <property type="protein sequence ID" value="EXK78977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8D7"/>
    <dbReference type="HOGENOM" id="CLU_023205_0_0_1"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="28"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="4">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK78977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="273" mass="30779" checksum="0B8425BE275F7819" modified="2014-05-14" version="1">MSPYRCVRCSTFAHNTLLKSDLAHSALRYDNEPEVGRGIKASGVPREEIFLTTKLWNTYHNRVEQGIHESLRNLGVDYLDLYLIHWPVSLPADASNTVNDRVLPDWDFIKTWAEMQKLVERGLVRAIGVSNFTISHLERLLSAPSTTIVPAVNQVELHPLNPQPNLHEYCTKRSIHLTAYSPLGSQDSPLHSLPQLQEISQNLGKTVAQVLLAWGIKKGWSVIPKSVSRLRILENLGSDFSLPDEDFAILEGIKERQRLIDGQDFLPISVFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8E6</accession>
    <name>X0C8E6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658489">
        <property type="protein sequence ID" value="EXK78987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8E6"/>
    <dbReference type="HOGENOM" id="CLU_059772_0_1_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052635">
        <property type="entry name" value="Sec_Metab_Biosynth_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39607:SF1">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39607">
        <property type="entry name" value="XANTHOCILLIN BIOSYNTHESIS CLUSTER TRANSCRIPTION FACTOR XANC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="27200" checksum="7295099FBD8FDFED" modified="2014-05-14" version="1">MPMTQSAYAHPTSLRALIKPEEDWTKISDFGKRRKIQNRLAQRKYRNKVKRLAGSSDDVEADKPRQKPTKCKRRSSASRSRKPRSTGPRIPGVSQHQFNSPVKPTGEPGFPDTYDDQISSNEQFRLGCPVNPASIEIPLPLYDFTQPDIDIVTAGEYAASTMSSTVPMPPSLATHFSDSINSETYPSSDGFNPYMAYSNMTPMELNYLSLYDQLYLHTPSLLYSSDQSVDILQAGLDCSITHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0CA29</accession>
    <name>X0CA29_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Inosine triphosphate pyrophosphatase</fullName>
            <shortName evidence="13">ITPase</shortName>
            <shortName evidence="13">Inosine triphosphatase</shortName>
            <ecNumber evidence="13">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="13">NTPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">XTP/dITP diphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_09006</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ITP + H2O = IMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:29400"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(6)-hydroxy-dATP + H2O = N(6)-hydroxy-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:83971"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:233529"/>
            <dbReference type="ChEBI" id="CHEBI:233530"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:83972"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>XTP + H2O = XMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:28343"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="13"/>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CA29"/>
    <dbReference type="eggNOG" id="KOG3222">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082080_1_1_1"/>
    <dbReference type="OrthoDB" id="6288734at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009204">
        <property type="term" value="P:deoxyribonucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.950.10:FF:000003">
        <property type="entry name" value="Inosine triphosphate pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03148">
        <property type="entry name" value="HAM1_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027502">
        <property type="entry name" value="ITPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="RdgB/HAM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067:SF9">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 13" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="65"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00054940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00093218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00093255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00093271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK87669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="195" mass="20928" checksum="C68352DDDD264D57" modified="2014-05-14" version="1">MNDINLITGNANKIADIKATLAPAGITVHSQSLDLPEIQGSIEEITIAKCRRAAEMVGGPVVVDDTALCFNAMDGMPGPYIKFFLEAMGPEKLHLLLAGFSDKTAQAVATIRYCQGPGHEPLLFQGRINGTIVPARGVMRYGWQTCFQPDGMGLTLAEMPDEEKHKMSHLGIALQKFTAWLKGDQHPADAVGSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CA63</accession>
    <name>X0CA63_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="7">HIU hydrolase</shortName>
            <shortName evidence="7">HIUHase</shortName>
            <ecNumber evidence="7">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_06722</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="7"/>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CA63"/>
    <dbReference type="eggNOG" id="KOG3006">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023419">
        <property type="entry name" value="Transthyretin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395:SF7">
        <property type="entry name" value="5-HYDROXYISOURATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="URICASE AND TRANSTHYRETIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00769">
        <property type="entry name" value="TRANSTHYRETIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="9">
        <location>
            <begin position="9"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK91310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="144" mass="16031" checksum="EC9A4F8E59EA0806" modified="2014-05-14" version="1">MASPTKDPITCHVLDTQAGRPARGIRVRLEGPIPPSTNPHSAAQPRPNTFESMTDDDGRVTAWLPYLSEDVAGEPPLQTLVEVLEDRKGQGSSRWTLRFDTGAYFGEENTFFPEVTVTFRVEEGQTYHVPLLLSPYSYTSYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBX3</accession>
    <name>X0CBX3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-catenin-like protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_05933</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBX3"/>
    <dbReference type="eggNOG" id="KOG2734">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017098_0_0_1"/>
    <dbReference type="OrthoDB" id="1898821at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:001136">
        <property type="entry name" value="Beta-catenin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039678">
        <property type="entry name" value="CTNNBL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013180">
        <property type="entry name" value="CTNNBL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978:SF0">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08216">
        <property type="entry name" value="CTNNBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01156">
        <property type="entry name" value="DUF1716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Beta-catenin-like protein 1 N-terminal" evidence="7">
        <location>
            <begin position="90"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK91930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="584" mass="65161" checksum="974249942BBAB4A6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCB3</accession>
    <name>X0CCB3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_15160</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JH658448">
        <property type="protein sequence ID" value="EXK80297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCB3"/>
    <dbReference type="eggNOG" id="KOG1212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_9_2_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF11">
        <property type="entry name" value="AMIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="91"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="243"/>
            <end position="246"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK80297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="546" mass="59736" checksum="841BEE81E67902E1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCV3</accession>
    <name>X0CCV3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCV3"/>
    <dbReference type="HOGENOM" id="CLU_2333657_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="98" mass="10929" checksum="6FDB10E3ED3976EB" modified="2014-05-14" version="1">MKQRLTVGWATHYLHAELQAVTQQTSESTYLFDGINTKIIGDLARNIAGWGEARRLADISQSSGLQINDRTVEGMRGHKRKDQSEERSGGRCTAQPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCX7</accession>
    <name>X0CCX7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-haloalkanoic acid dehalogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979337">
        <property type="protein sequence ID" value="EXK80517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCX7"/>
    <dbReference type="HOGENOM" id="CLU_045011_2_0_1"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF4">
        <property type="entry name" value="ACID DEHALOGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="27194" checksum="959B3B795D25A3C9" modified="2014-05-14" version="1">MQTTSKHVVFDIVGTIVTYDSILDALETRLGDRLRAEGVKPTMLGYMWFEISEREYTYLSITGQYHRFFDVFCSIFYRMLWIGGIKEPRSFATDEDLAYIVGHFKDLPLREGAAECLQLLRDAGFTVWGFTAGDTEQVRGYFLNNGIDMPLENFISCDDTGLGKPALDAYKPLLDQLGSDEKWFAAAHMWDASSAKKAGYKGAYCTILEKESCADIFGTMDVMADTLPEMARKIIQASKGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD70</accession>
    <name>X0CD70_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658440">
        <property type="protein sequence ID" value="EXK80607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD70"/>
    <dbReference type="HOGENOM" id="CLU_3143122_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="49" mass="5494" checksum="A73556A7484A88BF" modified="2014-05-14" version="1">MDHLATEGLNLSHRHIYGKAQEFRTDKGVGPNKIKGVEGTSTHTYFGMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDC1</accession>
    <name>X0CDC1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDC1"/>
    <dbReference type="HOGENOM" id="CLU_3224608_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="44" mass="4997" checksum="6665A24A77BEB282" modified="2014-05-14" version="1">MSVTQEVPSVNKAVNSVRQLDGEEMMKHDVDTTRSLKLNEWVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDE6</accession>
    <name>X0CDE6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDE6"/>
    <dbReference type="eggNOG" id="ENOG502SSWB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087179_0_0_1"/>
    <dbReference type="OrthoDB" id="5347452at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="261" mass="27862" checksum="8D1C1C3BC81734DA" modified="2014-05-14" version="1">MGILDDLIPRPTAPPATRTLKRRAVTSSQTTTQEITITIAPDNTCGYISERLGASRACPLNDWCYFFPPVPAQSFTNGGVLCCGETSCQYHATCVNSEEYFVSSKCDGGCEVDNYTLKCTDSASPYCNTVSWEGSTFDYWCNDLDISTAQSAALTYKGQTSREFGTINERDYSSLLSQMTEAKTEGSVNAEATGTATSQSTATETNKDSGSSGTPVGAIAGGTVGGVAALAIIGRSSVFLPPPKEEEQSFKFIKIPTSTWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDP0</accession>
    <name>X0CDP0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">D-aminoacyl-tRNA deacylase</fullName>
            <ecNumber evidence="2 6">3.1.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_08197</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a D-aminoacyl-tRNA + H2O = a tRNA + a D-alpha-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the DTD family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="2 6"/>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDP0"/>
    <dbReference type="eggNOG" id="KOG3323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076901_0_4_1"/>
    <dbReference type="OrthoDB" id="275783at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051500">
        <property type="term" value="F:D-tyrosyl-tRNA(Tyr) deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106026">
        <property type="term" value="F:Gly-tRNA(Ala) deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.80.10:FF:000001">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="entry name" value="D-tyrosyl-tRNA(Tyr) deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00256">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472:SF5">
        <property type="entry name" value="D-AMINOACYL-TRNA DEACYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="D-TYROSYL-TRNA TYR DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="DTD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK88944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="153" mass="16734" checksum="3A2D720CD514FBA7" modified="2014-05-14" version="1">MKVILQRVLSASVTVDKEMISSIGKGVLAFAAVAPGDTEKEADLMAAKVLRMKLWDDDEGGKWKKSVSDIGGEVLCVSQFTLLASTKKGAKPDFHGAANPEEARRLYHYFVQKVRAGYMEERVKDGQFQAMMEVALVNDGPVTLELKNGAKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEX9</accession>
    <name>X0CEX9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-L-rhamnosidase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEX9"/>
    <dbReference type="eggNOG" id="ENOG502QVGI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007933_1_0_1"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035398">
        <property type="entry name" value="Bac_rhamnosid_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF4">
        <property type="entry name" value="ALPHA-L-RHAMNOSIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17390">
        <property type="entry name" value="Bac_rhamnosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939348" description="Alpha-L-rhamnosidase A" evidence="1">
        <location>
            <begin position="18"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="2">
        <location>
            <begin position="404"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase C-terminal" evidence="3">
        <location>
            <begin position="754"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK89783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="831" mass="90888" checksum="E23E4E04FDD3571B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CG92</accession>
    <name>X0CG92_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CG92"/>
    <dbReference type="eggNOG" id="ENOG502SNXF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_8_1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF7">
        <property type="entry name" value="DJ-1_PFPI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="1">
        <location>
            <begin position="65"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="257" mass="28430" checksum="231525E2DFA075B8" modified="2014-05-14" version="1">MSSKQLHIGVFMPSSVQLLDLATVDVLASMSKEYLRLLPLPAHISEIAPSTKITYITSPKLFPTVNLTADLSVRASHTYEDDDVSPGKLDIIVVPGTDPADEFEEASTKWLRDHFNTVGVDVLCVCTGVYLCGAAGILDGRRVSGPRGLQDELIQKYPNTHFVGEEYRWIQDGNLWSSGGITNGNDLMAAYAQAQNKYWPNSISKLGAMLVDVGDRPQIYHQSQRKFFIVFAWQVVQGWLFSMVPFGKGMSKAKKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHV1</accession>
    <name>X0CHV1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_04955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHV1"/>
    <dbReference type="OrthoDB" id="1294322at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_eL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="Ribosomal_eL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_eL20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021138">
        <property type="entry name" value="Ribosomal_eL20_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10052">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002190">
        <property type="entry name" value="Ribosomal_L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160374">
        <property type="entry name" value="RplX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL20" evidence="5">
        <location>
            <begin position="6"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK93741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="176" mass="20681" checksum="22E575C2867193ED" modified="2014-05-14" version="1">MSSGRLQEYEVIGRHLPTEANPTPALYRMTIFAPNETVAKSRYWYFLRGLKKVKKATGEIVSVKTIHEKHPLKVKNFGIWIRYDSRSGTHNMYKEYRELSRTDAVESLYSDMAARHRARFRSIHILRVVEIEKTEDIKRPYIRQLTQKGLSFPLPHRITKENTKKIFSAKRPSTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIJ4</accession>
    <name>X0CIJ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycine-rich domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIJ4"/>
    <dbReference type="eggNOG" id="ENOG502RYJ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010103_3_1_1"/>
    <dbReference type="OrthoDB" id="2684236at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009836">
        <property type="entry name" value="GRDP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365">
        <property type="entry name" value="ENOLASE (DUF1399)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365:SF7">
        <property type="entry name" value="GLYCINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07173">
        <property type="entry name" value="GRDP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="624"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="755" mass="83450" checksum="84F9EB691E31CC0C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJ45</accession>
    <name>X0CJ45_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_13023</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJ45"/>
    <dbReference type="OrthoDB" id="3529975at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF64">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="36"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK82592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="361" mass="39728" checksum="0BA000559BDEFE5C" modified="2014-05-14" version="1">MSGWTYNAPSGSPTDGPQITSIAVVFTAVALLTVLLRVYVRGFMLKSVGADDWIIIVTWIASCGFAVVTVIQTKWGLGLKKLDDLPPQNYYNFMLLQFMGAPFYISSILGFKLSLLISYLRFMASGIWYKVTVGVAVACTLFHLSFLIAQINLCTPVRKQWDLSITHGSCLKGVPMYTTMASITIVFDVVVMMLPFPTLLKLQMPNRKKVVLLGLFAMGIFISIIQIVRIQTIKSLSNLLDSAALIKWSMVENNLGIIVACVPTLAPLVRYFSEQSRVGSRSRSKSQNNSGYALQSTYRKNLSRRSGLQPLGSGVDEQIGDSAEDILAKEDGIMRKTEIVISSAQGPLDRGELAPGHYHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKZ7</accession>
    <name>X0CKZ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Endo-xylogalacturonan hydrolase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_12544</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Pectinolytic enzyme involved in the degradation of xylogalacturonan (xga), a galacturonan backbone heavily substituted with xylose, and which is one important component of the hairy regions of pectin. Activity requires a galacturonic acid backbone substituted with xylose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658405">
        <property type="protein sequence ID" value="EXK83192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKZ7"/>
    <dbReference type="eggNOG" id="ENOG502QTHU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016031_1_3_1"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF9">
        <property type="entry name" value="ENDO-XYLOGALACTURONAN HYDROLASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936479" description="Endo-xylogalacturonan hydrolase A" evidence="15">
        <location>
            <begin position="22"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK83192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="43426" checksum="6FD55814305CBC28" modified="2014-05-14" version="1">MLFQSVFFAPLLSLLAQGVAGTPTLHDHSLAHHKRATCTPKSAGSASTDDVPTIVAALKQCGNGGVIVFPKDTTYMIRTKLSLAGCTNCEIQLDGRLKLSDDYTFWNNSRTQIDVRGINGLKFHSPAGTGEIDGNGQAAWDRFGSVGDLKRPVMFAVEGSTDVEVNGFLMKNAQNVFVDIGSNSERVKFLNMDLTAISKSSYPPKNTDGFDIGASKYTTLSNIFIQNEDDCVAFKAGCDQVTITDITCQGSHGLSVGSLGKTNTDTVTNVYVRNATMKGATKAAGIKIYPGGPDHGTAVVRNVTWDGVIVDNCGAAFEFDACYNEDESYCEQHPSTAQVSEIYVKNFSGKTSTKYAPTTGHVYCPVEGKNCDVEFTNWTVKSGTGAGQFLCENISSDVLGITCKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLQ3</accession>
    <name>X0CLQ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLQ3"/>
    <dbReference type="eggNOG" id="KOG4626">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001305_0_0_1"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19959:SF119">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19959">
        <property type="entry name" value="KINESIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="731"/>
            <end position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1070" mass="119563" checksum="5B6B81BC5A968BBC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM26</accession>
    <name>X0CM26_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">B30.2/SPRY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_12122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001887_1_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12885">
        <property type="entry name" value="SPRY_RanBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044736">
        <property type="entry name" value="Gid1/RanBPM/SPLA_SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936492" description="B30.2/SPRY domain-containing protein" evidence="6">
        <location>
            <begin position="24"/>
            <end position="1975"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="426"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1115"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1154"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1296"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1400"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1477"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="7">
        <location>
            <begin position="1748"/>
            <end position="1951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="382"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK83602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1975" mass="222234" checksum="F6C7E05495707155" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMP0</accession>
    <name>X0CMP0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMP0"/>
    <dbReference type="eggNOG" id="ENOG502QSKG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_0_0_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="39196" checksum="0A3832B08BA17E2D" modified="2014-05-14" version="1">MAEENNSQPAQAVTDVSGLLPPEHWAEVAEELGDTDSALGDDTAESTASITSSILQYRNINGRTYHHDIGNAQYWGTNDEKQNESMDINHHVLTLVLDGALYLAPIPKDIKNAIDIGTGTGIWAIDFADSFPDAQVIGTDVSPIQPGWIPPNLRFDIEDCTQEWTFAPNSQDYIHFRWLVGSIVDWDQLFKEAYRCLKPGGYIESHEALSRMDCDDGTITEKSAMHQWGKFFVEGGKKIGRSFTIVEDGVQRSAMEKAGFVNLVERDFKVPIGGWPKDPKMKEIGKYAQATLEQDIEGYVLFMANTVEGWTKEEVEVYISMLRRELRQGNMHPYYWQKVVWAQKPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMR2</accession>
    <name>X0CMR2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glucose repression regulatory protein TUP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_06053</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMR2"/>
    <dbReference type="eggNOG" id="KOG0266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="17410at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000111">
        <property type="entry name" value="Transcriptional repressor rco-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013890">
        <property type="entry name" value="Tscrpt_rep_Tup1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08581">
        <property type="entry name" value="Tup_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcriptional repressor Tup1 N-terminal" evidence="8">
        <location>
            <begin position="19"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="367"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="402"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="450"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="488"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="541"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="583"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="90"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="137"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK92119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="620" mass="66965" checksum="C51F65DF6357C425" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMS0</accession>
    <name>X0CMS0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMS0"/>
    <dbReference type="HOGENOM" id="CLU_2812422_0_0_1"/>
    <dbReference type="OrthoDB" id="5076103at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="67" mass="7560" checksum="62AB627EDD7C82F1" modified="2014-05-14" version="1">MCFIHTTRLVCKTCGHQDAVPRTAPCSEANNVEKPCKKQRMQTTTLIDASKCPQCKAKEYKTEAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN26</accession>
    <name>X0CN26_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN26"/>
    <dbReference type="HOGENOM" id="CLU_1865205_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="134" mass="14999" checksum="D5FBA69F418461B4" modified="2014-05-14" version="1">MRPLTPEIQNYHSKENPHGEMRVVSWYVQLACVADPQSVHHNCQRWCSCVLKWNVLCLGQIDPANFVQGDLELFQDGNVAGSRVCNANHISSFPPLNESASEVLYRYGLCVTETETFHSGHAVLDGKLISSNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNJ6</accession>
    <name>X0CNJ6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNJ6"/>
    <dbReference type="HOGENOM" id="CLU_3399407_0_0_1"/>
    <dbReference type="OrthoDB" id="10428967at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="35" mass="3578" checksum="8B35FF2191E5439A" modified="2014-05-14" version="1" fragment="single">MASNWYKGGVDGGELSLGDCAAHVLSARKGGVDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPB2</accession>
    <name>X0CPB2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPB2"/>
    <dbReference type="HOGENOM" id="CLU_1677960_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="148" mass="15713" checksum="EDF2B3BF2077AC83" modified="2014-05-14" version="1">MLVLVQKLSSFRTSAVATAWGVVTTTAPATWPGSASFWSVSARDICSSLVPGGVSMSRKSVSSQSTSLRNCRIIAVFFGPLQTTASPRLGRRKPRLIACRDPRPLDESPSCTNTGAHPPGTCVTFDSSIESMRGIEGPVKSTSRIPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR99</accession>
    <name>X0CR99_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02342</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR99"/>
    <dbReference type="eggNOG" id="KOG1110">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070889_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000018">
        <property type="entry name" value="Heme/steroid binding domain protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF76">
        <property type="entry name" value="CALCUTTA CUP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="4">
        <location>
            <begin position="108"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK96970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="268" mass="30654" checksum="FD68079A103E2999" modified="2014-05-14" version="1">MADESTLRQRKPQPKNETESEVSQPSTPTKKGKKRSSAQVDEEDPWDGYSPYLDVVRVISFIIVASMGLSYVISGGESFWWGHKNKPNWMTQRFYKDLILGPPPPVYMTLEELSIHDGTDPDRPLLLAINGTIYDVSNGRRMYGPGGSYSYFAATDAARGFVTGCFAEDQTADLRGYEETFLPLDDPEVDSHWTPEELAELKIKEREEAKKKADAALQHWVDFFANSKKYTKVGYVYREPDWLENEKPKKLCDQAQRSRKTRKIPKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSA6</accession>
    <name>X0CSA6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein CSN12 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_04954</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN12 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSA6"/>
    <dbReference type="HOGENOM" id="CLU_031567_1_0_1"/>
    <dbReference type="OrthoDB" id="10252687at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000366">
        <property type="entry name" value="COP9 signalosome complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045114">
        <property type="entry name" value="Csn12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732:SF0">
        <property type="entry name" value="PCI DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732">
        <property type="entry name" value="UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="252"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00073854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK93739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="455" mass="51957" checksum="2336CF7259EEFDA2" modified="2014-05-14" version="1">MNTLFDQFAEAHSQKNGYKLAQTLSPVAPPDDPHRLMAVWRSTNSHSVKGDIKHFVKSSTSHRRKMSHDETTGWVEVYTSYWKAIAEILAGESGKSTWTKVYEAWKELTSVLIRGYNSHGFEAWTIPSLYMVGKYLRLFAVKSDEERQAKTFDTGPGASLISDDFDPETDKQLQLRDCEGHLKRIFSLCLNDRAPLEESRKWGIYFVINLLFKTYFKLNSASLSRTILKTLAVYNDKGDMPPLEMFPKSQRVTFKFYEGVLLFLEENYNKAESHLNEAWQLCHKDALRQSERILTYLIPCRLLTSHVLPTKALLENYPRLQELFLPLASCIKSGNLQAFDKALQDGEAEFVKRRIYLTLERGRDIALRNLLRKVFIAGGFDEPKEGETTPVRRTRIPVAEFQAAVSMGSGHMVDPDEVECMLANMIYKELMKGYIARERGIVVLSKKGAFPGTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUA7</accession>
    <name>X0CUA7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uroporphyrinogen-III synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUA7"/>
    <dbReference type="eggNOG" id="KOG4132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051874_0_0_1"/>
    <dbReference type="OrthoDB" id="5595751at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10090:FF:000011">
        <property type="entry name" value="Uroporphyrinogen-III synthase (UroS), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390">
        <property type="entry name" value="UROPORPHYRINOGEN III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390:SF0">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="HemD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrapyrrole biosynthesis uroporphyrinogen III synthase" evidence="1">
        <location>
            <begin position="54"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="335" mass="37168" checksum="BF7860CA0076D324" modified="2014-05-14" version="1">MNPYIYASDQSQLIMTTTNSTAEQASRIPVLLLKTRSSPGDSYEDLFSESSIHGSGFAPQFVPVLLHQFHSDGMKEVAALLRDRRIGNQEHHEYGGLIFTSQRAVEAFVKLVEDGKAEDTPNPEDNTSWPHLQNIPVYSVGPATTRALAAVPQDPPLKVFGSHTGNGAALAPFILAHYYEWYRDQARATLPPILFLVGETRRDIIPKTLQDGALPDTERIRVTETVVYGTGVMESFPVDLRRVLSETRNDPMRWIVVFSPTGCDSMLRVMGILDPETNKVYKGYERDGKTFIATIGPTTRDHLLSFGFEPDVCAESPTPQGVLEGIQAFMAKRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUM8</accession>
    <name>X0CUM8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gelsolin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUM8"/>
    <dbReference type="eggNOG" id="KOG0443">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002568_0_1_1"/>
    <dbReference type="OrthoDB" id="6375767at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008154">
        <property type="term" value="P:actin polymerization or depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11290">
        <property type="entry name" value="gelsolin_S1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007122">
        <property type="entry name" value="Villin/Gelsolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977:SF130">
        <property type="entry name" value="SEVERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977">
        <property type="entry name" value="VILLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00597">
        <property type="entry name" value="GELSOLIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00262">
        <property type="entry name" value="GEL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gelsolin-like" evidence="1">
        <location>
            <begin position="69"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="1">
        <location>
            <begin position="193"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="1">
        <location>
            <begin position="316"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="396" mass="44143" checksum="17EC17722D1B64C6" modified="2014-05-14" version="1">MAPNQGLVHPKEYDIKDSNVELIGSDIDHQVKYNSALTEPAWNDGKVGVEPGLLVWRIEQFEVIPWPKEKYGQFYDGDSFIVLFSELIGSNDGTEKLVHDIFFWLGKHTSQDEAGTAAYKTVELDEFLKGSATQHREIQEAPSDDFLALFPRISIRSGGIESGFRHVEEEEEPKQTLTLLRVFKNPAAGANGVVVHEVEPTWTSLDDTDVFVLDVGDKIWVWQGKDCSPMEKAKAAQIVHDMTVAKHSEVEVIAQTESRSRRIVDLLGGDDETPREGFHCKKPFTPRTADKASKKLFRLSDASGQLFFGLVKEAERILHDDLESDDVFLLDDGGRAIWVWQGSGSSAAEKKSWFKVAQAYVRHLQAESGHEDAYLTPVAKVVEGGESRAFTKALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUY8</accession>
    <name>X0CUY8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_09971</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUY8"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019048_3_0_1"/>
    <dbReference type="OrthoDB" id="1588579at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="10">
        <location>
            <begin position="93"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="472"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK86297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="523" mass="57485" checksum="41332BD6629CB9E9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVA9</accession>
    <name>X0CVA9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVA9"/>
    <dbReference type="eggNOG" id="ENOG502SQZA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038508_2_0_1"/>
    <dbReference type="OrthoDB" id="5401654at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39610:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39610">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="382" mass="40156" checksum="C9542F4F4CEBFB2C" modified="2014-05-14" version="1">MTGMPDLNSVPPSPHTLAASRRQSSTQMATPPAPASPSLNILPSNQNTVNPSHSPSLPSPVLNASQPTYHAPSNVLAEPGVGPGPGPIRHPRPLTAAELHLQLEKEQEAVVNRLTRELSLLRAAQNASVVSNTSSTSAGNSTHDVPEQSLLSGSGFSIPTARHHRTSSTTSQSFGNQQLSSSYEARIHAPRPSQATPLSRQDSTASRRSLTSSPGPQHSSLDPSNYFQHQRIPPPTSIPPSSVGATPGSMSEQLSPGLMPATMRYEETAYYRNELETAKKENDALKRKIRELERQVRQRRASDASRPRSGSASTSASVSVTPTGGASIAGPREGLPIRPGGERERGMTTQSIASVASVGVGVPEEELKVGESAASAGVAQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVM1</accession>
    <name>X0CVM1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVM1"/>
    <dbReference type="eggNOG" id="ENOG502RMTF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1578651_0_0_1"/>
    <dbReference type="OrthoDB" id="4977394at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="169" mass="19092" checksum="FEAE4C88501D187C" modified="2014-05-14" version="1">MSQVPYIEVYRFNDHIKSLQEKAIVEVLTSTPGEKQSRLGTYGLEKPCADLSDEVIRGLSGPLVRWATSRGAVIQDLQRPCFRSEAFRLQKGSALWPGSHSTALLVPLSNRNAQIELIPRGSNEAITHNWDPRTVIHLNEMGLQFQGNGSVRFIYILFQTAPCPKRQFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVN5</accession>
    <name>X0CVN5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVN5"/>
    <dbReference type="HOGENOM" id="CLU_164879_0_0_1"/>
    <dbReference type="OrthoDB" id="4467949at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="110" mass="13186" checksum="8F95C7FD1262215D" modified="2014-05-14" version="1">MTTRNLNKTWRDVVFEQYQADLDADSPFPIRYLIFAHQWKKDIFINIPNKIEMMTLRRAVLDFARSRSQEEDPTFSNEHISVWPRKTFRERQEEEATKESNETNESGFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVW6</accession>
    <name>X0CVW6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_01469</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVW6"/>
    <dbReference type="eggNOG" id="KOG4209">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054059_0_1_1"/>
    <dbReference type="OrthoDB" id="252020at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061574">
        <property type="term" value="C:ASAP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12365">
        <property type="entry name" value="RRM_RNPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034201">
        <property type="entry name" value="RNPS1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15481:SF0">
        <property type="entry name" value="LD23870P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15481">
        <property type="entry name" value="RIBONUCLEIC ACID BINDING PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="94"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="176"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK98615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="316" mass="34923" checksum="CA84ABE6E796B4CC" modified="2014-05-14" version="1">MASRSPSRGRYRSRTRSPAARSERSRSPQRRHHHDSRSPARSTSPQRRNGRYRSRSRSRSRSNSRSRSRSRSWSRGARDRNDRDRSASPAAKSTKIVVERLSKNINEQHLYEIFGQFGRIKDLDLPMNRTFGTNRGTAYILYDYEDDAEAAIAHMHEAQVDGSAINVSIVLPRRKLSPAPPTARRGANIDPRVPFAGTRGGPPGAGMGGNNGMGGGGGGRRRASPGSRYGPRSDVYRPGSRSPSRSSAGPPPSRGGGGSRYRSRSNNSFSSRSRSRSPGPRRKAAGRHDDHETRRRGSIDSREGRSRSRSRGRGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CW42</accession>
    <name>X0CW42_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CW42"/>
    <dbReference type="HOGENOM" id="CLU_2061597_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="116" mass="13481" checksum="FF903E8D692AC235" modified="2014-05-14" version="1">MFNSQHVYTLRPDQLQYTYLVIMPTVYSTLMIHNQGFTQIGTSNQHFQLHFRMYACMFNTESKPHPIHTIPVLTLTSRYTRKVPVILNHTRSTLPMIPTSFRTHPAAKLVLKHGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CW66</accession>
    <name>X0CW66_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Autophagy-related protein 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_01523</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ATG13 family. Fungi subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CW66"/>
    <dbReference type="eggNOG" id="KOG4573">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70161at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034497">
        <property type="term" value="P:protein localization to phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040182">
        <property type="entry name" value="ATG13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018731">
        <property type="entry name" value="Atg13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13430:SF4">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10033">
        <property type="entry name" value="ATG13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autophagy-related protein 13 N-terminal" evidence="6">
        <location>
            <begin position="75"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="333"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="375"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="596"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="793"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="397"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="432"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="514"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="546"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="632"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="686"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="853"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="894"/>
            <end position="905"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK98715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="930" mass="100039" checksum="2DBE33EDB347D117" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXG2</accession>
    <name>X0CXG2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXG2"/>
    <dbReference type="HOGENOM" id="CLU_1447752_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="231" mass="25372" checksum="20A9565DC59FC019" modified="2014-05-14" version="1">MDENDAKHRRERSRKAAKAGTETHRRAEPALTWTGLTQAGYCDGISTQSGGDNSVTAPIHGDSQACGPRIRTGIMGRGASPTRRAGVVGYFLGFLLIQTDSSHLSSASDSDCSRSLAHQDRLCCPNRTMLRPVKPFARPPWDFFLPTQPNHRLLPNHQHDGTLKHALPPSLTVLFNPRALLHYASSPQLLEQGHLNRAHFIAIVVSQASHQQSHAMTCNKNMAQSTYHATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYB2</accession>
    <name>X0CYB2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA repair protein RAD50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_03356</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMC family. RAD50 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0962">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006184_0_0_1"/>
    <dbReference type="OrthoDB" id="18797at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000947">
        <property type="entry name" value="DNA repair protein RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001195">
        <property type="entry name" value="DNA repair protein rad50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004584">
        <property type="entry name" value="Rad50_eukaryotes"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00606">
        <property type="entry name" value="rad50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867">
        <property type="entry name" value="RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13558">
        <property type="entry name" value="SbcC_Walker_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="17">
        <location>
            <begin position="6"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="493"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="744"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="799"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="977"/>
            <end position="1074"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK96253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1307" mass="149931" checksum="4E46FE6633345BA0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYL5</accession>
    <name>X0CYL5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">26S proteasome regulatory subunit rpn11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_03438</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYL5"/>
    <dbReference type="MEROPS" id="M67.A11"/>
    <dbReference type="eggNOG" id="KOG1555">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052991_0_0_1"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="9">
        <location>
            <begin position="34"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="308"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK96378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="337" mass="37718" checksum="1246759E8D3B552B" modified="2014-05-14" version="1">MERFRSLLGGGGMGLGGAAHGTDNTNLIDNSETVYISSLALLKMLRHGRAGVPMEVMGLMLGEFVDDFTVKVMDVFAMPQSGTGVSVEAVDPVFQTKMMDMLRQTGRPESVVGWYHSHPGFGCWLSSVDINTQQSFEQLNPRAVAVVIDPIQSVKGKVVIDAFRLINPQLLMLGQEPRQSTSNLGHLNKPSIQALIHGLNRHYYSIGINYRKTALEENMLMNLHKHVWTEALEMDDFRHEGCKNKDRLQQLVSLADGYEKRVKEETELTKDQLKTRYVGKLDPKKHLEDVGQELIEDNIVSVSRQMIDKEATMPRKEGQAGPKGQVNGEQMDVEEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYP3</accession>
    <name>X0CYP3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYP3"/>
    <dbReference type="HOGENOM" id="CLU_3392353_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3476" checksum="D04A4CC57A6387E9" modified="2014-05-14" version="1">MKKKKKKAGVVRPARGNIRQGLRGAGWQVGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYP6</accession>
    <name>X0CYP6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYP6"/>
    <dbReference type="HOGENOM" id="CLU_010972_0_0_1"/>
    <dbReference type="OrthoDB" id="5104176at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="582" mass="66202" checksum="0FFA90D98460FC38" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYS2</accession>
    <name>X0CYS2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GIT Spa2 homology (SHD) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYS2"/>
    <dbReference type="eggNOG" id="ENOG502QS1N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5588096at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005826">
        <property type="term" value="C:actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902716">
        <property type="term" value="C:cell cortex of growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005078">
        <property type="term" value="F:MAP-kinase scaffold activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013724">
        <property type="entry name" value="GIT_SHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039892">
        <property type="entry name" value="Spa2/Sph1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056439">
        <property type="entry name" value="VBS_C3G9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601:SF0">
        <property type="entry name" value="PROTEIN SPA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601">
        <property type="entry name" value="SPA2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08518">
        <property type="entry name" value="GIT_SHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23742">
        <property type="entry name" value="VBS_C3G9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00555">
        <property type="entry name" value="GIT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="2">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="2">
        <location>
            <begin position="200"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK96014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="922" mass="100791" checksum="2F74FE0E730C2256" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1N4</accession>
    <name>X0D1N4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_00538</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3B1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1N4"/>
    <dbReference type="eggNOG" id="KOG0213">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002242_0_1_1"/>
    <dbReference type="OrthoDB" id="438939at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000066">
        <property type="entry name" value="Splicing factor 3B subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000069">
        <property type="entry name" value="Splicing factor 3B subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000810">
        <property type="entry name" value="Splicing factor 3B subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015016">
        <property type="entry name" value="SF3b_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038737">
        <property type="entry name" value="SF3b_su1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12097">
        <property type="entry name" value="SPLICING FACTOR 3B, SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08920">
        <property type="entry name" value="SF3b1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Splicing factor 3B subunit 1" evidence="9">
        <location>
            <begin position="238"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="10">
        <location>
            <begin position="995"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="12"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="131"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="237"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXL00322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1210" mass="134438" checksum="4CC3D6E1E2CEB247" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0D274</accession>
    <name>X0D274_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00833</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D274"/>
    <dbReference type="eggNOG" id="KOG0779">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007693_0_0_1"/>
    <dbReference type="OrthoDB" id="442460at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070139">
        <property type="term" value="F:SUMO-specific endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057501">
        <property type="entry name" value="DeUb_enz_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051947">
        <property type="entry name" value="Sentrin-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896:SF3">
        <property type="entry name" value="FI06413P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25424">
        <property type="entry name" value="PH_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="7">
        <location>
            <begin position="526"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="102"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="406"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="690"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="841"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="486"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="714"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="856"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="877"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="899"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1002"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1023"/>
            <end position="1043"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL00871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1069" mass="119035" checksum="005F582EBD084CE2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D285</accession>
    <name>X0D285_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Spindle pole body protein pcp1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_02780</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502R0AV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002168_1_0_1"/>
    <dbReference type="OrthoDB" id="10255000at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1480.30">
        <property type="entry name" value="Designed four-helix bundle protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012943">
        <property type="entry name" value="Cnn_1N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019528">
        <property type="entry name" value="PACT_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07989">
        <property type="entry name" value="Cnn_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10495">
        <property type="entry name" value="PACT_coil_coil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomin N-terminal motif 1" evidence="8">
        <location>
            <begin position="177"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Pericentrin/AKAP-450 centrosomal targeting" evidence="9">
        <location>
            <begin position="1369"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="592"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1125"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="969"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1146"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1158"/>
            <end position="1169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK97658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1489" mass="170825" checksum="45819CA3EA7CE201" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7J5</accession>
    <name>X0D7J5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pls1 tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7J5"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="26559" checksum="B1515EF13E32DC48" modified="2014-05-14" version="1">MVDKIFLSTVAADALFLSSGVMELVFSLVVQSKMKDMPTDGEDVTRNLLYQRFPLTAGIVNAIFILVTFAVTLPGLVMPARSFLKVSGYMVTVCAIFTMCVAVFLWVMTLRMSEQFFNIYIEQEPDVQSLIQDSFQCCGYFNSTTPAFVMDSTCSSPASAALLRGCATSISSFANLHIDGIFTVLFGIVGESKLTFLAQLHAKTSQVTNIPYRYRCYLYLVHRMSAQGSQRARTLPTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCU6</accession>
    <name>X0DCU6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Zinc/cadmium resistance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_05548</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCU6"/>
    <dbReference type="eggNOG" id="KOG1483">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013430_4_0_1"/>
    <dbReference type="OrthoDB" id="9944568at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF5">
        <property type="entry name" value="DIFFUSION FACILITATOR FAMILY METAL ION TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="9"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="11">
        <location>
            <begin position="270"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK92372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="43971" checksum="254494CCC0F130EF" modified="2014-05-14" version="1">MKITKKQRLIATICISFSFFAAELAVGFYTHSIALIADAFHYLSDLIGIVIALMALMLQEHTKPAPQGYTYGWHRATILGAFFNGVFLLALGISILVQAVERFVHLTCVQQPFLIMIVGCVGLALNILVLSFLHEHDHEHDHQGGRRHSHDDRQQNQETTGPLTNEAISESVTGLAQIPMNHHNHRHTTVSVKSPGRDLGMLGVFIHVLGDAINNIGVIIAAVLVWQLKGEGRYYADPAVGVFISLMILLSAIPLVKKSGAILLQTAPKGVNPEDVKHDIEMIPGIKSVHELHIWRLDQCKFVASAHIVVDSRTVQGFADKAKIIMKCLHAYGVHSATLQPEVLEASPVIMPGSGPGSQGQATSIDANHSVCRTQRSRGGEQECQVICGSSCDGLRCCAPVHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0DKH3</accession>
    <name>X0DKH3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 6</fullName>
            <shortName evidence="6">eIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TIF6</name>
        <name evidence="7" type="ORF">FOQG_03660</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer. Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <text evidence="6">Shuttles between cytoplasm and nucleus/nucleolus.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eIF-6 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DKH3"/>
    <dbReference type="eggNOG" id="KOG3185">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071894_0_0_1"/>
    <dbReference type="OrthoDB" id="4155914at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00527">
        <property type="entry name" value="IF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.75.10.10:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00323">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006413">
        <property type="entry name" value="IF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="6">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="6">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK94872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="246" mass="26615" checksum="EAFF77F7B71E1777" modified="2014-05-14" version="1">MAVRAQFENSNEVGVFSTLTNSYALVALGASENFYSVFEAELQDIIPTVRTTIAGTRIIGRMTAGNRKGLLVPTTTTDQELQHLRNSLPDSVRIQRIEERLSALGNVIVTNDHIALVHPDLERETEEIIADVLGVEVFRQTVADNVLVGSYMSLSNQGGLVHPKTPIQDQDELSSLLQVPLVAGSVNRGSNVVGAGMVVNDWLAVTGLDTTATELSVIESVFRLGEGQGPSNINTSMKDTMVESFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0DKZ9</accession>
    <name>X0DKZ9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DKZ9"/>
    <dbReference type="HOGENOM" id="CLU_2757840_0_0_1"/>
    <dbReference type="OrthoDB" id="10268795at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="70" mass="7667" checksum="98867E65F6901859" modified="2014-05-14" version="1">MTPPTAHYSHNDNDIPTTNTTLIKAQDPKKRKVDSHIQQLYWSVCPLGGVLTYTKKNGINCGGGVIITLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0DQY3</accession>
    <name>X0DQY3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DQY3"/>
    <dbReference type="HOGENOM" id="CLU_1042222_0_0_1"/>
    <dbReference type="OrthoDB" id="5100704at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="267" mass="30699" checksum="A15E2C616D7B7618" modified="2014-05-14" version="1">MARHHHLHEHQHDADQPDMPTMRGRPRHSEDETPGGNDEQRTEETAVNIVDGLPRTGLVVFDDCLPRYFSLPTPRSSLFPLQSTLLLSSLEVHIPNHQHSRHRPRDYGRQPAECDQVWPPQRRAPRSKTSEQKIDAQNETHAPSKDEVYDINPEYDDPKRNTGQNDANEEDTPNFEGHRPPPATFNLLRILPKVEIYARSTLFIRNPQESGPQTDICARIPGNDNNWAARVSCYDSLFDLYDWVRGNSSEESPEVCQHQRHSHCVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DTM4</accession>
    <name>X0DTM4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DTM4"/>
    <dbReference type="HOGENOM" id="CLU_129414_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="104" mass="12284" checksum="9DFFA2351F7439F0" modified="2014-05-14" version="1">MLEMRDSLEENMFELCRLMEHKDGGLPRELVEKKMMYYLEFIFRLAGEGDEQSTILEQELAKMELALSWVSGLIRHWDEHVSTVLFADAMEQNPHHHQRHQGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DVR2</accession>
    <name>X0DVR2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DVR2"/>
    <dbReference type="eggNOG" id="ENOG502QQEZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020826_0_0_1"/>
    <dbReference type="OrthoDB" id="442243at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF2">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="507"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="613" mass="67432" checksum="94601286310C9399" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3G1</accession>
    <name>X0B3G1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979554">
        <property type="protein sequence ID" value="EXK76271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3G1"/>
    <dbReference type="HOGENOM" id="CLU_038125_1_0_1"/>
    <dbReference type="OrthoDB" id="5302720at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="451" mass="49140" checksum="2D3CCEAADD0560BA" modified="2014-05-14" version="1">MKPAHVRDRHSGLAKPAKPMVLVRANAFMRIHLLNRHLDSHSLFDCQTISYSLPFLESSSQKKTIMRITPLLLLTPFVQAIVHPGLLHTEADFTRIRSFVNATREPWLTGWNKLVARTNPNYSPSAAVVVCRGASWCDPQNYPVLYRDAHAAYVNAIYWKVTGNTAYADASARILDAWATTLTTVTGSSDKALVAGLQGYQLANAAEILRTYSSWKGLPAVVNMLNRVFLPMNDDFLRNHYGASIYHYWANWDLANLASLHAIGVLGDNQTAINQAVNYFKTGAGMGAINNAIWHVHKESGSGKRLGQGQEAGRNQGHALLDFALLGVLAQQSYNQGQDLFALNNNLILAGAEYVFKYNTGKDVPFETYVNPDQGTATAISASGRGGLRPIAELIYAHYDGVKDLNASWTGAYRDLVVQGAGGAEGGGGDYGSTSGGYDQLGFGTILFRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5E3</accession>
    <name>X0B5E3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658620">
        <property type="protein sequence ID" value="EXK77335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5E3"/>
    <dbReference type="HOGENOM" id="CLU_135737_0_0_1"/>
    <dbReference type="OrthoDB" id="5080340at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="134" mass="14872" checksum="FCFEC275E9EA9F82" modified="2014-05-14" version="1">MDPDASCCLQSTQNAGQDLRSSQGCKTSQSSIESAQSLQLEAKMEKLGRDIRILKRLVRPQKKSKYRHFRHNQAPVYIKSFSLTINTSTNTPTTPKESHGLHLSCSQLIPGTPNEEGAVDEDRVAQRDSEDDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9I1</accession>
    <name>X0B9I1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16912</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658521">
        <property type="protein sequence ID" value="EXK78421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9I1"/>
    <dbReference type="HOGENOM" id="CLU_2589859_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="80" mass="8585" checksum="080BC9F441E9BDA2" modified="2014-05-14" version="1">MSLDAAQATLELLLDLGHLIVAAVKPPKTFDAYKADANEVATAYTSGKIRQNLLKSPCYRDQDNLQGVAYILVSGNTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BA63</accession>
    <name>X0BA63_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979915">
        <property type="protein sequence ID" value="EXK75693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BA63"/>
    <dbReference type="HOGENOM" id="CLU_119141_0_0_1"/>
    <dbReference type="OrthoDB" id="5093965at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="161" mass="17421" checksum="F28048E85B05EAA7" modified="2014-05-14" version="1">MKKKKQKKKAPPIGSARDFPCRPCVTRATKSPGYECASQDNTGAACWACAKNGHTCRPVPPGAVAAVRAFWELNRQIDDMNEDPCDAWRSAAQRAAQQLRACSAAPAPALAPRGEADGKTLEERKVAALEAIAEAARLWTQLNKLDEESVEEDEDGEDEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAA0</accession>
    <name>X0BAA0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979856">
        <property type="protein sequence ID" value="EXK75738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAA0"/>
    <dbReference type="HOGENOM" id="CLU_2277600_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="102" mass="11126" checksum="BE5118EF3EE8D929" modified="2014-05-14" version="1">MACLAVLSSFSKILGGQSSLPKRYRVCRTHSLGGQKRLASMLGSRLSSLPSSVRRFIFCAPIAVGARRDRTWSRKPHSTPVTCCESHSPTNTTSWTSSLKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAU2</accession>
    <name>X0BAU2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658475">
        <property type="protein sequence ID" value="EXK79260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAU2"/>
    <dbReference type="HOGENOM" id="CLU_821450_0_0_1"/>
    <dbReference type="OrthoDB" id="5107514at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="338" mass="38264" checksum="558E927BE0D9808B" modified="2014-05-14" version="1">MSVPGYRKFCFRSERNRANNTLSPNADDIEEVSTTDQLKRRKRNSTDISRGRSALNATDIPHHLPKKTCNIVETITTQIDHRLSAGLETDDSVQRVLRGDATSKTNGRAAARRISLDMPIDLTASLTSIDAATYQPRQDESNTSFQQINEPDTAIVSTIPQEEGRGDATQPGLTHIVKLALSLGTIEQLMERLEDAESLAKATETMIFEAKLVESNVKVKEETVESIFDTVLSSIQQLRVDGYQADSRGRRSQAKFKAYRSKVKEEAINLVLQEKHEEQEASRRSIERCKQKMKLLVDERERRERQVAVLRWCLVIRQLFSDLEKGVFGTEVEFLLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC60</accession>
    <name>X0BC60_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_16022</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658473">
        <property type="protein sequence ID" value="EXK79371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC60"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000068">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF19">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01812)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="58"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK79371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="503" mass="55742" checksum="A984BC22E43A73AF" modified="2014-05-14" version="1">MADLEKPFPVETEKVDNTTIEYERAQLLAHLPDPDAGKTVEERQAIEKKLMWKVDLALIPWLSFLYLLSFLDRTNIGNARLAGLEVDLKMVKGDYNNALTIFFVSYAVVEPATNALLKKITPRLFFTLIILTWGLIMTLMGLVTNVKGLLAARFFLGMAEAGLFPGVNYYLSCWYKSSEIGIRSSIFFSAAALAGSFGGLLAAVIAKMDGIGGKPGWAWIFILEGLATIVAGLACWWLVFDWPATASFLSPDDQIRIQRRLIMDRQGRTAEDFDKRHMFAALKDWKTYGYMLIYMGCLTPLYAFSLFLPTIIAGMGHAGTKAQLLSVPPYAVAAALTICVGFYGDRTRQRGYCNIAIVLLGIAGFAMLIATSNPTVQYVGVFLGAAGIYPTVPNTLSWLNNNTEGSLKRAFVLGVVVGWGNLNGVVSSNIYLLREKPRYYTGHGVVFGYLVVFLLGGSILMHLGLRKMNRDRSLGKMDAKWDSLSDEQKWVQGDLRPDFKYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCF5</accession>
    <name>X0BCF5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979495">
        <property type="protein sequence ID" value="EXK76508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCF5"/>
    <dbReference type="HOGENOM" id="CLU_1129098_0_0_1"/>
    <dbReference type="OrthoDB" id="3364132at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="1">
        <location>
            <begin position="9"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="263" mass="29083" checksum="473C190F05A62965" modified="2014-05-14" version="1">MGVLPFTPGINIAVLVDGKPAKEYQPWEFPEPFDATMNQGILHTKCYIESQAGSPYAIRFRISSLFTFPDDTDAITISVYVDGKPFDNKCIQKSTLAGASNLGVEYVDEISYCQRDFSDGSSEYYRPVFDDIRPGKSTATIIDYKITNTNTVDEADGKSVNSDLQRIKTSGTIQVAIEVGKQTAPVPMGDDNFCDDKRNESLAIDNKALLLNGYGQIHGTTYTKTDETRQMTYTAVDDEQHLGNFFFYLSISSFSCGSVLLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCW7</accession>
    <name>X0BCW7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_18932</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979538">
        <property type="protein sequence ID" value="EXK76324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCW7"/>
    <dbReference type="HOGENOM" id="CLU_044876_0_0_1"/>
    <dbReference type="OrthoDB" id="10000533at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF4">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK76324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="306" mass="33857" checksum="E45A5FAEBA612159" modified="2014-05-14" version="1">MPTVAVAGGSGHVGRTIVEVLGASKEHEVLVLGRSVPEKNKMDQAFVVVDYVDIEATAALLKTRGVHTIISAIVIIDPPSSSSQVNLVRAAALSGTVRRFITSEWSVPHSEDSALYVFREAAVEALRETNLQWTRIVNGYFLDYYGLPYLKSYLTPFTFAVDIANKAAAIPGTGNDIVYFTYTFDVAKFVVALLGLSDWDETTYCYGDKATWNEILQLAEESRGSKFTASYDALEKLQKGEVTELPSHRESYGFFPKPALRGFLSLLGRYVVEGRFDIPADKALNAKFTEIQTLKVKEAIELWRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCX5</accession>
    <name>X0BCX5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="11">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_18922</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="11"/>
    <dbReference type="EMBL" id="KI979534">
        <property type="protein sequence ID" value="EXK76334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001103_16_0_1"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18794">
        <property type="entry name" value="SF2_C_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000296">
        <property type="entry name" value="ATP-dependent DNA helicase RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018982">
        <property type="entry name" value="RQC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF153">
        <property type="entry name" value="RECQ-LIKE DNA HELICASE BLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09382">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00956">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="861"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="1048"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="104"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="217"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="687"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1355"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1566"/>
            <end position="1591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="344"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="441"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="695"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1361"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1566"/>
            <end position="1577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK76334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1591" mass="177475" checksum="266E8F916953E4EF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDH4</accession>
    <name>X0BDH4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_18390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979436">
        <property type="protein sequence ID" value="EXK76878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDH4"/>
    <dbReference type="HOGENOM" id="CLU_023747_0_0_1"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF3">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK76878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="722" mass="81321" checksum="4F9923D02B2F81E3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEB7</accession>
    <name>X0BEB7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Isotrichodermin C-15 hydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_14994</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658442">
        <property type="protein sequence ID" value="EXK80500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEB7"/>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK80500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="532" mass="60893" checksum="3ADC914E44C68FE0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BG44</accession>
    <name>X0BG44_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_17482</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658568">
        <property type="protein sequence ID" value="EXK77813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BG44"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF12">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK77813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="60522" checksum="FC240C76036B026D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHT5</accession>
    <name>X0BHT5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658520">
        <property type="protein sequence ID" value="EXK78428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHT5"/>
    <dbReference type="HOGENOM" id="CLU_2197129_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="108" mass="12105" checksum="B3611DB79E9BCE6E" modified="2014-05-14" version="1">MGKTSKCAPQDEDQEDEIGDSGDDALITSSPSKDRASKRRRRNPETESESQHQPEPVSTEATEDTEDEEDEEDTEGSQGINSSSDQAKRVPSIQEYRKRIDADRHPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI61</accession>
    <name>X0BI61_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_13818</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658421">
        <property type="protein sequence ID" value="EXK81840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI61"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_3_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000090">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF72">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="16"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="511" mass="56656" checksum="50B76854A4CCDF3B" modified="2014-05-14" version="1">MALFSLGRGASVQAGVTICCLVAFVLFGYDQGVFGGILQNEDWQNQFDRPNDAKTGIIVSCYNLGCLAGCVINFFVGDKLGRRRTIWLAMVLVLVGATLQTTAYNVPHLVIGRVVTGFGTGIKTSTVPMYQSELCEAESRGRLVSSEVLFVGVGITIAYWFDFGMSYVGGAIAWRLPIAFQMVFALGVVVLVFALPESPRWLFVKGRDQEAINVLCQVHDKDPSDPYIVSESTSIQKAIELELAANKNDSFLSIFRNDTIRTRYRILLAWGVQFMNQAGGINLVVYYIPSVLVQNVGLSPRMSQVLGGCINMMFMFGSILPSFALDRMGRRKTMIWGCTGLSICMLMVAVLLSRVGYSNGHTCASAAVAFFFLYMLIFGMSVNCVPWVYVPEILPLESRTRGTAIGISSNWLWNFTVVMITPVIINRLQWKAYLIFMVTNLLFVPAFYFFYPETSNFKLEDVDLIFSQGGNPVSVARQMTKDMRRNNINVNSNGTISVDTEKSQTMIVESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKE2</accession>
    <name>X0BKE2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658415">
        <property type="protein sequence ID" value="EXK82301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKE2"/>
    <dbReference type="HOGENOM" id="CLU_640993_0_0_1"/>
    <dbReference type="OrthoDB" id="5428890at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="354" mass="41052" checksum="51AAF2EA9C9BD8FC" modified="2014-05-14" version="1">MALRQLKSDGKYGILNKIWPRMTRSDFDTYMDLYDRYFLFLEEQMELIERKSILYSTKSIEELASIIDRIRQYPHKPKSEVFENSSEETMRSADMAIRIWLMIHIQHSSSGSTNSWWWPKTMPLNLLLQNWSTPSKKQDRKSRQISQSFSIANLAHYYGFQVKWTSDLAQHLSIDWEYKQITIFEHVICLRNHLAYPDDCPLPKRFVGEAIDTIKLLFPDDKDTKAFLSRDGRKFLKIPFGRERSLSLGDFSYWETEISQLLDVWEQGPSGWSQLRLRPDRSNFLEYSTFWAAAVVLLLTVISIVFGVAGLVLAKKALDVSVKSLDVSVKSYELSLAIACAEANATETLPAFCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKI2</accession>
    <name>X0BKI2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKI2"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_3_0_1"/>
    <dbReference type="OrthoDB" id="19653at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050466">
        <property type="entry name" value="Carboxylest/Gibb_receptor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23024:SF242">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23024">
        <property type="entry name" value="ARYLACETAMIDE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="1">
        <location>
            <begin position="72"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="302" mass="34681" checksum="A0ABCCD0419B4BA5" modified="2014-05-14" version="1">MADHTFWQYIRLKVIVTFIRLINYIFTRPHFTPSPTCIRKLIRIPSRDLNRFINAWIYYPNNYTDSQKLPLVINWHGGAYTLPNLGMDHHFCEKLASENNVLVLDADYRKAPEYPLPGALEDAEDTFRWVEGQRIFDLDRVALSGFSSGGNLALVASSELRREFKMNIRAVYAFYPGVDFSIPPEEKKVPEPIRPLPVSFQHLLTEAYVPRVEDRKSPKASPMYAEAISFPEHVMLVACSGDIFTPEIEVFGKKLERAGRDVEVVRIQGAHGCDKTTNPTMFRAEARDFAYSKVLQSLQYIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKJ0</accession>
    <name>X0BKJ0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658472">
        <property type="protein sequence ID" value="EXK79413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKJ0"/>
    <dbReference type="HOGENOM" id="CLU_075109_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="321" mass="36236" checksum="66810005626F3B07" modified="2014-05-14" version="1">MRSLAAKQRQCTCSARFRTEIDLKRHLSDHAEQRRVSLIRTLFSIANHDTPQIRERMIGDLQAEALKHEAHTEADDESSSESDIDQDSDGDSESEGTRAEALVCPSCPRSAPFPTRQKLRRHHEQDTECHEVCVFCHVSFKRVRKFKRHAETCVGDSERKRAYMDETCKELTILSDTKLEKALRERKKLSRDESEQAANSVERAGRNPRAPKRQRTRQRHADNATDAPNLLPWAAPTAIDHYLVRSSGAPTAPANVHIQNQTLSLSTEATEAVVPSLGVLEEFDAPLMHIMNSVPLETYSWPVHPYDGNLPGNDPAAYRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLA9</accession>
    <name>X0BLA9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PEP-utilising enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_12782</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLA9"/>
    <dbReference type="HOGENOM" id="CLU_1875515_0_0_1"/>
    <dbReference type="OrthoDB" id="5093372at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030:SF1">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEP-utilising enzyme C-terminal" evidence="4">
        <location>
            <begin position="61"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK82950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="14900" checksum="C50B0188015021A9" modified="2014-05-14" version="1">MSNSPELLYHIILTVIDYHVDHSEAKQSIYISGTNATLEAAESSAFRVLGTLRNKPEDLGELADLFNKEDEAVKQMIAQVISVTCNKGYKIRRCGQTPSKYPEFAKFLVDAGIDSISVSPDSLVAVTRHVVASVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLC0</accession>
    <name>X0BLC0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658475">
        <property type="protein sequence ID" value="EXK79259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLC0"/>
    <dbReference type="HOGENOM" id="CLU_035730_5_2_1"/>
    <dbReference type="OrthoDB" id="43654at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05382">
        <property type="entry name" value="CAP_GAPR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034113">
        <property type="entry name" value="SCP_GAPR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935817" description="SCP domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="105"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="250" mass="27517" checksum="BAF3292DC852DFD7" modified="2014-05-14" version="1">MRFSSYVVSLMATGAVAAPHDDNWQNGNKHSKLVTKFEYVTRYLVGEGGSPQTTCVPQPQKSDFKQHIPAPVYAQPATAQFVNEPKHAPNQDSSFDFGPSYGLSTDQEKAIHLHNEARKAVGNDPLSWDDTLAYGAQEWADHLASKRLLQHSQGGDGENLYMGTTDSPYSAAVKAFLAEGSQYNGEAISGSNYMSFGHYTQCVWKYTTKVGMGVSKDSSGTSWVVARYQKPGNMQVPKKRVFMLHSLILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLT5</accession>
    <name>X0BLT5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658471">
        <property type="protein sequence ID" value="EXK79439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLT5"/>
    <dbReference type="HOGENOM" id="CLU_088303_0_0_1"/>
    <dbReference type="OrthoDB" id="5033111at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="290" mass="33617" checksum="E29AC146A2009D7B" modified="2014-05-14" version="1">MWSSRPHSRLEVTDINEFTELVNQIMRDMKDIACAFKGPKPEEVNDRETVCEYNKLLQLMDFDVKLAHSNMDRDTAFKYPWITTKNCEERLKILELSIQVFADTVVDAGSSKIACIPPFTKLAIMFETIVIEYLKLRHRRTVMQLDGAVKDKGVGRDTRRLNKEEVLSYVSRPFSKEFITNCLRQYHAKSIPRGAIYLKVAWDGNKGAWAVKQGHWVDPRVPELENGAIRVIMIEPKELLNSPYKVKEQYDEENIRLPHSLLQRCKLDFLDREDGVLHWSLGSVLTWGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNG5</accession>
    <name>X0BNG5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="11">3.2.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_15045</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="11"/>
    <dbReference type="EMBL" id="JH658444">
        <property type="protein sequence ID" value="EXK80458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNG5"/>
    <dbReference type="HOGENOM" id="CLU_016031_1_0_1"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047911">
        <property type="term" value="F:galacturan 1,4-alpha-galacturonidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000027">
        <property type="entry name" value="Probable exopolygalacturonase X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF14">
        <property type="entry name" value="EXOPOLYGALACTURONASE X-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937057" description="galacturonan 1,4-alpha-galacturonidase" evidence="15">
        <location>
            <begin position="22"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK80458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="436" mass="47295" checksum="395434DFC0B4D113" modified="2014-05-14" version="1">MIQSAFFGVLASLACIGNVVAHEWLPVPRPEIKAWPHSPGGTFPVSPHRVKSCYVKASNNGGDDAASILHAFHTCNNGGTVVLAANYTIASPLDLTFLKHVDVAITGTINFAPDLSYWTEHSFKYTYQDATAFWRFGGEDVNIFGHGVGLINGNGQPWYDAAATNTSLLRPVLFLVDGLRGGSVTGLRMIYPPSWFNLIANSTDIIVSDLDLQAVSKNSNLAKNTDGWDIYRSDSVVLQNSVINNGDDCVSLKPNSTNIVVQGLHCNGSHGISVGSLGQYAKEFDIVENVYVYNISMSNASDGARIKVWPGQYTAFQDNLNGGGGSGYVKNVTYDGLFNTNNDWAIELTQCYGQKNLTLCNEFPSNMFISDVVFKNMWGTTSKRYDPKVGTLVCSDALKCSNIQAHNISVSPPSGKIATWVCTNMNNSRLDINCGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNH9</accession>
    <name>X0BNH9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNH9"/>
    <dbReference type="HOGENOM" id="CLU_1815903_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="142" mass="14419" checksum="F0B4B40BBB9F6A32" modified="2014-05-14" version="1">MLITSPVAAAPGAPSASVASKAAMSSCTTSEPASEWVPSTTGTPITETTFGGNEIAPVSSTISSAQGLSLSQLLMLADTAADRFDLLPDNTQFLFDFNQRQGAAGEGGNLTVANRKTFPALIGTGAGMAVGHIGRKTYQISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNY8</accession>
    <name>X0BNY8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cutinase</fullName>
            <ecNumber evidence="2">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_11852</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cutinase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="2"/>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNY8"/>
    <dbReference type="eggNOG" id="ENOG502S3AW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040058_2_2_1"/>
    <dbReference type="OrthoDB" id="2975078at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050525">
        <property type="term" value="F:cutinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF2">
        <property type="entry name" value="CUTINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00129">
        <property type="entry name" value="CUTINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938757" description="cutinase" evidence="9">
        <location>
            <begin position="17"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="71"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="206"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK83900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="262" mass="28374" checksum="C195524C1E87EEA5" modified="2014-05-14" version="1">MKPTQALIALAAIVYAAPVVEQTKALAPPLAELDTHFEHHIKRCGKDEPPFLGRFPFANETYNQLTDGTPCRNVTMIYARGSRQAGNVGKANNTGPALFNSLADRIGLENLAVQGVTYKARRRDYIFKGGCNEGSKTMARLINQAASQCPDTKIVIAGYSQGAQLLHKAAKNVTAGVTQHIAAAVTLGYPEKPMGKIAASRSLSVCRPGDSFCDKTIPWKPFVPFVGAPLWWFLTMLDTHGDYNENATAVANWIADRVTNIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPX1</accession>
    <name>X0BPX1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14969</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979337">
        <property type="protein sequence ID" value="EXK80534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPX1"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_0_1"/>
    <dbReference type="OrthoDB" id="4500315at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000396">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000009">
        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF4">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="537"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="564"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="600"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="632"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="129"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="79"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="371"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="402"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK80534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="670" mass="73950" checksum="4221E590DFD61D6E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ39</accession>
    <name>X0BQ39_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_14463</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979336">
        <property type="protein sequence ID" value="EXK81033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ39"/>
    <dbReference type="HOGENOM" id="CLU_008599_2_3_1"/>
    <dbReference type="OrthoDB" id="3364175at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF3">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="6">
        <location>
            <begin position="245"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK81033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="627" mass="69688" checksum="52355B7E49C9C240" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ47</accession>
    <name>X0BQ47_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ47"/>
    <dbReference type="eggNOG" id="ENOG502STJH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1896626_0_0_1"/>
    <dbReference type="OrthoDB" id="3908196at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="134" mass="14806" checksum="AD4FFACB00F787CE" modified="2014-05-14" version="1">MWATVQAAGQQNQYPVYTDCSGFTWQESTPNNKNAACGRATTKKVYCPCEYMVECQKFSWGRKLPSQVRINVYNRDGSLRADMYQIKIGAQTLRGESGCGKAGAIAEVLASFVPGVGQYFDKGIKIACRQGSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQF9</accession>
    <name>X0BQF9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Galactinol synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQF9"/>
    <dbReference type="eggNOG" id="KOG1950">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049943_1_0_1"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="39608" checksum="3892F62ACFFF9FDD" modified="2014-05-14" version="1">MADNVTRHNAYATLITRDSYLPGVIILAYTLKRNVSIYPLVVLYTPNLPKDAKRVLELEAPKCNMILRECEHLLPPEGVKMTLIAERFADTWTKLRVFELFEYDAVCYLDADMAVLDNMDVVFKVETHLPDDWIAANHVCVCNLDSDSWAPEDWRAENCAYTPLEHPTALTEPLQPTETSPSPHKLLNGGMFIFHPSNVLWDRMLHVFNTTPLLSTFMFPDQDFLAFFFENKWYALGWQYNAIKTMRYWHPDIWRDEEVICLHYIVDKPWAKRVGLDGVAGYKGLDGVTHCWWWQLYQYWEDQRTSDGRGGNEAIAILKKLIAPEDTMEGGLGYLQVGLPVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRW7</accession>
    <name>X0BRW7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_14350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658428">
        <property type="protein sequence ID" value="EXK81199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRW7"/>
    <dbReference type="eggNOG" id="ENOG502RYZ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009377_1_1_1"/>
    <dbReference type="OrthoDB" id="103819at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK81199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="699" mass="77456" checksum="16BAB7A2FE2BA683" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS95</accession>
    <name>X0BS95_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11254</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS95"/>
    <dbReference type="HOGENOM" id="CLU_021599_5_2_1"/>
    <dbReference type="OrthoDB" id="3525185at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF2">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="498" mass="56061" checksum="90518795164EDEAB" modified="2014-05-14" version="1">MVMSSQSNSFMTSSTQPKRQPRRSKGCLTCRKRRVKCDEQRPTCERCSKGFHPCKYDDNLVFVNHLHDAAKTVRPGNPESRPLNALIQREDFKQIPVTIDLHGFKTEVVISFFVNNLFVLVKSPLEDGSSILDLFSGEANSTAGMSGLCVAEAFFSSIHGIPEMKFHASALYGQAVQRLKADLGTRTEASRSLPHTTIWSALFLGVYEMISSDSMSNWLQHCHGVAVLTEIAGPYGFQMDAAKPILQINRSFISIGAMADRKRTFLEQDEWKHIPWALQPMSKTIGDFLQDILCDIPGMMKDVDSLSNMNILSANLLSQKLQATFEQLNSLRISWNFMYPHSCWRQKMVRESSELCHDTLGQLICFSGLERAIDFVYFNTTHLILHSILGQLISLPNSCWVSDVGMSPDDNQFQEAPDLVFWNHENRYRNAQAICQCVDYMLQNEGGASGAFNLLFPLKVAYNHLSGSPIMQKWVAGVMEKISTTKGLSIGMQILEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSP2</accession>
    <name>X0BSP2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein SYM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11137</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSP2"/>
    <dbReference type="eggNOG" id="ENOG502SQQ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049109_3_2_1"/>
    <dbReference type="OrthoDB" id="10267969at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF80">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK84901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="23673" checksum="18A64370DF58C7E3" modified="2014-05-14" version="1">MVRALNLRLALQATAIKVSANLVTQIIIHYRTPGVSTFDAQQVLEFAIYGFIGSQVGNVIQFILEDCFPTGHAIRANEILPQVQADVKQVEEKKDDDTRGTTRRWFNISPDLIWRNVLAKLILDQTIGLAISGSVFLICTNIARVSHPFLVLEVIRNRLWPLIKAGWHIWPLVAICNFLWVPVRSRVLVAVCVGFGWSIFLSVFAMRKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSZ2</accession>
    <name>X0BSZ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSZ2"/>
    <dbReference type="eggNOG" id="ENOG502T5E0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013361_0_0_1"/>
    <dbReference type="OrthoDB" id="5052600at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938841" description="Apple domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="684" mass="73790" checksum="13D1CA2A6E75675E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTA4</accession>
    <name>X0BTA4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_13870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658423">
        <property type="protein sequence ID" value="EXK81694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTA4"/>
    <dbReference type="eggNOG" id="ENOG502SIT3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004083_2_0_1"/>
    <dbReference type="OrthoDB" id="3989227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF50">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK81694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="827" mass="92447" checksum="5928ABB7D9264CFB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BU63</accession>
    <name>X0BU63_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Theta class glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BU63"/>
    <dbReference type="eggNOG" id="KOG0867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_14_2_1"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF23">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN TPCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="92"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK82478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="25348" checksum="0093863E43B0F3F0" modified="2014-05-14" version="1">MAEMKPIKVLGVHGPNAGKIILLCEELGLPYETEIIPLTDVKNPNYVAINPNGRLPSIQDPNTNLTLWESGAIIEYLTETYDKDHKLSFTSGTAGAYHARQWLFFQTTGQGPYYGQAMWFIIYQPLPEARERYVKEVNRVTGVLEGHLAKQKPDADGNVWFLGGRLSYVDVAFFTWQHTAEPRIPNEEFNQDDYPHVKKWAENMLKRPSVQKVLKLQEAKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVH4</accession>
    <name>X0BVH4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13086</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVH4"/>
    <dbReference type="HOGENOM" id="CLU_006016_1_0_1"/>
    <dbReference type="OrthoDB" id="5093543at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="2">
        <location>
            <begin position="706"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1040" mass="117515" checksum="88E5E429DD3FC1ED" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWL8</accession>
    <name>X0BWL8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_12859</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWL8"/>
    <dbReference type="HOGENOM" id="CLU_014597_1_0_1"/>
    <dbReference type="OrthoDB" id="4835445at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF11">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK82899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="678" mass="76200" checksum="15E76E98856B381C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BY15</accession>
    <name>X0BY15_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BY15"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_4_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF213">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="361"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="659" mass="72494" checksum="7BB987B1F0BD05B2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYR2</accession>
    <name>X0BYR2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYR2"/>
    <dbReference type="eggNOG" id="ENOG502RF09">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096155_0_0_1"/>
    <dbReference type="OrthoDB" id="4629699at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="223" mass="24282" checksum="6E3CA84B5DE630EC" modified="2014-05-14" version="1">MKLSDQKEILRITASILRNKTVTMCHGHPRHHPCAHTSINWHYCPSALIDLETGYETPCSNTSFAAAQPTTSDCPLQNCQFKSKGGSWTCCSCQQGPNTQGWCTMPMSRMTMNPESFSVESFETTCDHGCCSKCVQYGSGRDASSEMTFSEIRKGSASRKFGYSSATKSHRRGSAFSLPASGEESTPSPSTSKSSSASSGYKVGMEYTSSKTKSSKKSHKSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZE5</accession>
    <name>X0BZE5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZE5"/>
    <dbReference type="HOGENOM" id="CLU_1602771_0_0_1"/>
    <dbReference type="OrthoDB" id="5416097at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="27"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="166" mass="19193" checksum="FBBD9B4A57CF161D" modified="2014-05-14" version="1">MATSKDSEAGREDNVWKRCLKLDGDCCVITGASHPHVYQILPFAWSKTKANLRTQQMIPALEVVVDLKPSNVKYEAVTKLRQGVGCTDSLWNVVCLSIQLHKWWDHAYFGQKYDGRANCLEEDFAQIHLQFLWMPRNIYRWATKQRVQRKAEVRISHRFAQSTAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZP2</accession>
    <name>X0BZP2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alanyl-transfer RNA synthetases family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11429</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZP2"/>
    <dbReference type="eggNOG" id="ENOG502S23F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_3_0_1"/>
    <dbReference type="OrthoDB" id="288942at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051335">
        <property type="entry name" value="Alanyl-tRNA_Editing_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462">
        <property type="entry name" value="ALANYL-TRNA EDITING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462:SF2">
        <property type="entry name" value="THREONYL AND ALANYL TRNA SYNTHETASE SECOND ADDITIONAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="4">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="261" mass="28974" checksum="611E063A1D34E18F" modified="2014-05-14" version="1">MDRFGHTEAVYHRDETQHVMETTVLASIPYADWDNSINKVFKDASDGLFLVITNSTIFYAKGGGQPSDTGTMTSRDQSSIFTVTSVQKLPSGTIMHLGTYSGAPFEEQTLVTQEINKDTRKLHSQIHDAGHILASAVRRLGIPDLREVKAQHYPGTAFVDFQGIIPGDRKEGIEQLANQIVNDDRSINVHWWSREELEAKSWTMPEDSDGQGGLVRAVEIDGEGAYMCGGTHVRSTALVGKIRVRKVKRQQGISRVSYELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZQ5</accession>
    <name>X0BZQ5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_19222</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979646">
        <property type="protein sequence ID" value="EXK76017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZQ5"/>
    <dbReference type="HOGENOM" id="CLU_1652040_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF9">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936686" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="21"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="71"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK76017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="170" mass="18100" checksum="86606B29021D3BA4" modified="2014-05-14" version="1">MHLFQLKVFTAVVVWSLTSAGATIPLAGDELAGKCPITDVDQLGKKLSKAAKIFFPGSNEFLQASTRWSVLEVPKVNIVVVPGTEKDVAETVKFANKKAVPFLAFNTAHGAITTLGRMDHGIEIYLSQLNDVKISPDGKTVEIGGGTVSKKVTDTLWAAEKQTGTSASID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C021</accession>
    <name>X0C021_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C021"/>
    <dbReference type="HOGENOM" id="CLU_3125088_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="50" mass="5773" checksum="98037EDDEB751B5B" modified="2014-05-14" version="1">MFHIAEQIEQATQIFEDVTNISNEWRPYLIVHVGIPIAWLSPSPRLKVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3D3</accession>
    <name>X0C3D3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein BZZ1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_08184</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Plays a role in endocytosis and trafficking to the vacuole. Functions with type I myosins to restore polarity of the actin cytoskeleton after NaCl stress.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the BZZ1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3D3"/>
    <dbReference type="eggNOG" id="KOG3565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015390_1_0_1"/>
    <dbReference type="OrthoDB" id="8783038at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045010">
        <property type="term" value="P:actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20824">
        <property type="entry name" value="C1_SpBZZ1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11912">
        <property type="entry name" value="SH3_Bzz1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000060">
        <property type="entry name" value="Actin polymerization protein Bzz1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000161">
        <property type="entry name" value="Actin polymerization protein Bzz1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000296">
        <property type="entry name" value="Actin polymerization protein Bzz1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000040">
        <property type="entry name" value="Actin polymerization protein Bzz1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035459">
        <property type="entry name" value="Bzz1_SH3_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020454">
        <property type="entry name" value="DAG/PE-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF21">
        <property type="entry name" value="PROTEIN NERVOUS WRECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00008">
        <property type="entry name" value="DAGPEDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="F-BAR" evidence="14">
        <location>
            <begin position="8"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="13">
        <location>
            <begin position="405"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="12">
        <location>
            <begin position="575"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="12">
        <location>
            <begin position="677"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="450"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="639"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="128"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="321"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="459"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="483"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="506"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="639"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00074946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK88925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="735" mass="81451" checksum="FECFDA3ECB48C12F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3U4</accession>
    <name>X0C3U4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3U4"/>
    <dbReference type="HOGENOM" id="CLU_1981680_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="126" mass="14584" checksum="9EF18CBC330EAAAE" modified="2014-05-14" version="1">MSWICILPRQLPYRVPRYQVLQAQGRNMANITVQYSLKINGQRNGHRLSKPPITAYHSHFPGTHSPRRSLLLQVFRAPLIMIISSLTRSANRNLLVIPRTVPASIQGCWYRFGRNVEEKWFTVVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4D0</accession>
    <name>X0C4D0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_17674</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658588">
        <property type="protein sequence ID" value="EXK77617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4D0"/>
    <dbReference type="HOGENOM" id="CLU_1786945_0_0_1"/>
    <dbReference type="OrthoDB" id="5054775at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031930">
        <property type="term" value="P:mitochondria-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021711">
        <property type="entry name" value="DUF3295"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053043">
        <property type="entry name" value="Ras-cAMP_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28014">
        <property type="entry name" value="NEGATIVE REGULATOR OF RAS-CAMP PATHWAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28014:SF1">
        <property type="entry name" value="NEGATIVE REGULATOR OF RAS-CAMP PATHWAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11702">
        <property type="entry name" value="DUF3295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3295" evidence="3">
        <location>
            <begin position="85"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK77617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="145" mass="16469" checksum="6E00B818525407BA" modified="2014-05-14" version="1">MTYRLDTHVLTVDANVIHKVDTENPAHLRSMWTVFSKCADSVEQGRRLENLSWRLWQRETFVVDNEEKTPPTTQTLPENIPSESRMPELSRSVESLVDEEAVVSSPVPAKLEIARPRVRRQDSCASTRSKRQGSSGSSSSQAIWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4E7</accession>
    <name>X0C4E7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4E7"/>
    <dbReference type="eggNOG" id="KOG3519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010210_0_1_1"/>
    <dbReference type="OrthoDB" id="8059989at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818:SF3">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="238"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="767"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="769"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="944" mass="106873" checksum="EEAC99BEBF739B3F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4S6</accession>
    <name>X0C4S6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_07520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4S6"/>
    <dbReference type="eggNOG" id="ENOG502QQ29">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015161_3_0_1"/>
    <dbReference type="OrthoDB" id="2943660at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF9">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="86"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK89415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="684" mass="76949" checksum="9ED5DC357406645D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C550</accession>
    <name>X0C550_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C550"/>
    <dbReference type="HOGENOM" id="CLU_3087260_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="52" mass="5470" checksum="A5DA8350530E091E" modified="2014-05-14" version="1">MAISQVPEAVGQGASCKSNDEAKPENESGREQTTAVEEGDVAGSMQTQSRSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5E1</accession>
    <name>X0C5E1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Actin-like protein arp-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_10069</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the actin family. ARP6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5E1"/>
    <dbReference type="eggNOG" id="KOG0680">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027965_1_1_1"/>
    <dbReference type="OrthoDB" id="6220758at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10210">
        <property type="entry name" value="ASKHA_NBD_Arp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000040">
        <property type="entry name" value="Actin-like protein ARP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK86019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="442" mass="49488" checksum="72F5F21F5600634D" modified="2014-05-14" version="1">MAGPRKPKPAPPKGPSTTLVLDNGASTIKAGLIHSSTIPSEPRIIPNVIARDRTRKIYVASELEKCRDFGEIQFRRPVEKGFIVNWEAQKEIWDREIFEREEFEPKDARLILAEPPNGLPILQANCDQIVFEEYGFASYYRGIGSTFNAYHDVQNIFRTPQEAPTVANTPAEAVMVIDSGYSHTTITPVLRGQPLQSAIKRLDVGGKVLTNYLTRLISLRHFDMRNDTYIVNEMKEISCYVSADFKADLEKSWKGTRGERRPDYLSGGGIAKDYILPDFHTRFKGTLVDYDPARHSKSRKLAAQSEEDALTLRNERFTVPEILFNPSDAGIRQPGLADLVYESLQELPIGLWPALLANIIVVGGNTHFDGFIQRLQKEVVQRVPDDCIVRVARPADPVTHTWFGGANLACHTNIERLAVTKAEYEEHGASWVAKKFAAGLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6F9</accession>
    <name>X0C6F9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleoporin NUP120</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_07443</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6F9"/>
    <dbReference type="eggNOG" id="ENOG502QQWQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003258_0_0_1"/>
    <dbReference type="OrthoDB" id="67716at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059141">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056548">
        <property type="entry name" value="HEAT_Nup120"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021717">
        <property type="entry name" value="Nucleoporin_Nup160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048884">
        <property type="entry name" value="Nup120_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11715">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23300">
        <property type="entry name" value="HEAT_Nup120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21486">
        <property type="entry name" value="NUP120_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup120/160 beta-propeller" evidence="4">
        <location>
            <begin position="76"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup120 helical" evidence="5">
        <location>
            <begin position="614"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin nup120-like HEAT repeat" evidence="6">
        <location>
            <begin position="833"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK90005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1162" mass="129909" checksum="EAB02F1E4F7114F0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6R4</accession>
    <name>X0C6R4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6R4"/>
    <dbReference type="eggNOG" id="KOG4178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083329_0_0_1"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF31">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN YCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="26"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="271" mass="30419" checksum="11B22574CDA71F86" modified="2014-05-14" version="1">MEFKPTRSIVHNEGCDLHYWYQGSGPLIIFVPGGNGHGRQFNNIIAALSGRFTCATFDRRQMSASQVPVNKRLSPPQQARDIRAIIKAVGFDEAILFGSSSGGTFAYQFAHDFPEMVVHLICHEAGLAMLLPDATQITEWMYDLLHTFETQGQDAAAEEFAKCLIGYDAEGIPKPASPEASNPKNFWEYEWAPLIGYCPNMFRIKEHGVSVGVMRGVRCKDAFYARAIEEQAKILECPRMTVPGHHEGFQCETEEFVPSLLEMLDILEKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6T8</accession>
    <name>X0C6T8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6T8"/>
    <dbReference type="HOGENOM" id="CLU_3143097_0_0_1"/>
    <dbReference type="OrthoDB" id="10271681at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="49" mass="5054" checksum="73A24005AE0CB4A5" modified="2014-05-14" version="1">MGVAASLALFQTQVAPDHARGLNRQTVSVGEKGAPQKKAPDGNFCVATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7D9</accession>
    <name>X0C7D9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7D9"/>
    <dbReference type="eggNOG" id="ENOG502RND4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_882960_0_0_1"/>
    <dbReference type="OrthoDB" id="4770059at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="373" mass="40313" checksum="F9FACE1936336599" modified="2014-05-14" version="1">MSSSTEDDESTSSGLSSIASAAPSSTISLSDPTPAPTTLVIAPKPTNEDDLDDDGIFPPMTTPWTGPVDCTWTYDANKVPKSGSDGLAAMLDLEPIAGAKSLSCYPDAMFDKGLTGVYSPGTCPHGWTTVSLRVDTSENRDDETTTAICCSSEYTLDGNLCKRSVSSVLAVPYTYNQTAQTYDAVSDTPTTLYGATIAVYTIRALFKDSDKDALGLKDEDDIPGTEHHGRSLSLGARIGIGVGVAVFVLLALGALAFWLTRRERKKTEKRRAHELGAVGSMRHTSPGPGDNFYAAADAIHRRDRTRQTAEPPPAYEAATDSNSMTENDSRLSEDTATRDEEIRALQVQKEAIQRRIEELERSETQSQEDNRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8H0</accession>
    <name>X0C8H0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">hydroxymethylglutaryl-CoA reductase (NADPH)</fullName>
            <ecNumber evidence="2">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16358</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="2"/>
    <dbReference type="EMBL" id="JH658488">
        <property type="protein sequence ID" value="EXK79012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8H0"/>
    <dbReference type="HOGENOM" id="CLU_001734_2_1_1"/>
    <dbReference type="OrthoDB" id="5077295at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK79012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="216" mass="23080" checksum="77F64C5403D2C5D1" modified="2014-05-14" version="1">MVTKATQHACEMLRHSLTHKYSIRGFLIEGQLASDKKPSWGNVKKPRGVETLVWGTISPDACREVLGCTTDQLYATQQILKEGGIRNGQFGCNVNPINIIAAMFIATGQDPASTAEASWSHLTSELHPKTGALTMSLYLPSLPVGTIGGGTGLPMQREALKMLKCDGDGAEQKQRLAGLIAAFGLALDVSTSAAVTNDTFTASHMRLGRGQERANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAK5</accession>
    <name>X0CAK5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAK5"/>
    <dbReference type="HOGENOM" id="CLU_3279478_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="41" mass="4505" checksum="0CB0137D95F10D74" modified="2014-05-14" version="1">MSSAVGHAGEAGDIDFPKTKTRKSLYLIWIPMFMDATSPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBT5</accession>
    <name>X0CBT5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dihydroneopterin aldolase</fullName>
            <ecNumber evidence="4">4.1.2.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">7,8-dihydroneopterin aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_08609</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde</text>
            <dbReference type="Rhea" id="RHEA:10540"/>
            <dbReference type="ChEBI" id="CHEBI:17001"/>
            <dbReference type="ChEBI" id="CHEBI:17071"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="EC" id="4.1.2.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DHNA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.25" evidence="4"/>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBT5"/>
    <dbReference type="eggNOG" id="KOG2544">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062068_0_0_1"/>
    <dbReference type="OrthoDB" id="5425486at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006156">
        <property type="entry name" value="Dihydroneopterin_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42844">
        <property type="entry name" value="DIHYDRONEOPTERIN ALDOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42844:SF1">
        <property type="entry name" value="DIHYDRONEOPTERIN ALDOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroneopterin aldolase/epimerase" evidence="8">
        <location>
            <begin position="173"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK88294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="313" mass="34281" checksum="7C00EBCF1E5B911C" modified="2014-05-14" version="1">MGKETPLVSSRRLSNAEGDPVAVVRVRNLQTTIQGPKDAWGRGSKQQPLLISAEVSLTHAFPSSSSDDKVASDTVHYGLLSKSILSTLEKLPRSALSLSDVLNRLWVDLTGFQYTGVKEPSAQNRKAFLDMSLIRRLSVSLVLPKASLMGSAIRLSGSCLFADSAITARSLELGLEGIRVPTLIGVNSNERNAKQVVITNIRIDEYQTAHDDYAVIESTIVDAMSESSFETLEALAASLAFHIARELRTKRDDFYGQIIRIGLEKPTAVPLAEAACVELTVRTEDVKIEVSKTKDVRFDDTRNQIAHSNDRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBY3</accession>
    <name>X0CBY3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBY3"/>
    <dbReference type="HOGENOM" id="CLU_126664_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="128" mass="14756" checksum="93CFDFF97A866512" modified="2014-05-14" version="1">MEGVKGKSQTTPWLQSYRTYRPVPHLHHFTVALFLSLEGLMPGTGIRQFCTCFFRASMLPHPATYLRFAPNLHLSLSVITFRHPTQPFLGENTCMCAHALFVSRQRQISHYPAHAQRPLTFWTRDVLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCM9</accession>
    <name>X0CCM9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_08386</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCM9"/>
    <dbReference type="HOGENOM" id="CLU_013748_3_1_1"/>
    <dbReference type="OrthoDB" id="10006023at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005948">
        <property type="term" value="C:acetolactate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00568">
        <property type="entry name" value="TPP_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF167">
        <property type="entry name" value="ACETOLACTATE SYNTHASE LARGE SUBUNIT ILVB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="THIAMINE PYROPHOSPHATE ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="6">
        <location>
            <begin position="3"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="4">
        <location>
            <begin position="216"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="5">
        <location>
            <begin position="391"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK88594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="560" mass="60379" checksum="13867EC24BE3BEB3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCN8</accession>
    <name>X0CCN8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FUN14 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCN8"/>
    <dbReference type="HOGENOM" id="CLU_106353_2_0_1"/>
    <dbReference type="OrthoDB" id="3990500at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="15922" checksum="9E89010A15C739E1" modified="2014-05-14" version="1">MNMHRAFNSRVAFRAMSRGIAPATCVGAFIATRPAIRCDAPTLATGPPPRRRPLEVSPDTVRQLSSGSVAGFGIGVVVALFSRTLALLTGLIAFSIHVASRWGLDIPRTLGIEKLLKNSSVWNKSKERPLFTASFLVTFILATFVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDK1</accession>
    <name>X0CDK1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_07942</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDK1"/>
    <dbReference type="eggNOG" id="KOG0841">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="5"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="236"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK89293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="275" mass="30406" checksum="AB96D20203D6E68E" modified="2014-05-14" version="1">MATERESKTFLARLCEQAERYDEMVTYMKEVAKLGGELTVDERNLLSVAYKNVVGTRRASWRIISSIEQKEESKGSDKHVSTIKDYRNKIETELEKVCQDVLDVLDDFLIPNAATGESKVFYHKMKGDYHRYLAEFASGEKRKGAATAAHDAYKSATDVAQTELTPTHPIRLGLALNFSVFYYEILNSPDRACHLAKQAFDDAIAELDSLSEESYRDSTLIMQLLRDNLTLWTSSDSAEGEAAGAADAPKKEEEAAKPAEPAAAPAEEPAPAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE04</accession>
    <name>X0CE04_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE04"/>
    <dbReference type="eggNOG" id="ENOG502STPC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167691_0_0_1"/>
    <dbReference type="OrthoDB" id="2565331at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40636">
        <property type="entry name" value="CSBD-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40636:SF1">
        <property type="entry name" value="CSBD-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="96" mass="9297" checksum="B2B9B966598BAB81" modified="2014-05-14" version="1">MNNNKNNNPAGNVGETVGGGLNFLTSTVGNTVGGLGRTVGNVTGAATRGLGDTVTSATGDAGRPLGDGIGNLGTGVQGGLDSISKGVENAGQWKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE09</accession>
    <name>X0CE09_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="4">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_05580</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE09"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07102">
        <property type="entry name" value="ALDH_EDX86601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000009">
        <property type="entry name" value="Aldehyde dehydrogenase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000012">
        <property type="entry name" value="NAD-dependent succinate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="5"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK92426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="467" mass="51284" checksum="D3750DECC72FDF51" modified="2014-05-14" version="1">MSLEVITTISPNTNEPILTRNGASQADLESLPKVATEAFQSYRKTTLKERQAIVRKFLDGLLAKKDELGEELTVQMGRPISYTPGEVATAVKRGEYLLKISDEALKDTDGEPEKGFKRFIRKVPVGPVLIIFAWNYPYLILVNSLIPALLAGCSVILKPSPQTPTIVERVTDLLKEAGLPDGVCQYFHCGSPTLMETIVRDPKIALVCFTGSVAGGLAVQQAASDRIVNVGLELGGKDPAYVRSDVDVDWAAAEIVDGAIFNSGQSCCSIERVYVDEKIHDQFVEAVQKVLKSYKLGDPFNKETQLGPVVSKRSKQTAEEHIKDAVDSGAKDATPENETFSNPPTKGNFVKPTLLTGVNHSMRVMTEESFAPIIPVMKVKDDSEAVKYMNDSEFGLTASIWTKDTDEGYELAEDVEAGTVFVNRCDYPAPDLAWTGWKNSGKGQTLSKFGFDQFVKLKSYHLKDYPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGL3</accession>
    <name>X0CGL3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_07184</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGL3"/>
    <dbReference type="eggNOG" id="KOG0406">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_9_1_1"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045174">
        <property type="term" value="F:glutathione dehydrogenase (ascorbate) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005442">
        <property type="entry name" value="GST_omega"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF13">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE OMEGA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01625">
        <property type="entry name" value="GSTRNSFRASEO"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="55"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="150"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK90388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="308" mass="35739" checksum="3C8B248B07E1F74B" modified="2014-05-14" version="1">MQQTYFLRALLSTSSRKTRFINIRTRSIMTNVDTSLPPEPTGAAAKFAAQHAEEHPLKLYGGWFCPFVQRTWITIHEKKIPHQYVEINPYKKEAYFMAMNPRGLVPTLAVPVDPKGKVQKPLFESNIICEYLDEAFTDESKYGPRLLPTDPYERARCRIWIDHISTRIIPSWYKLMQHTPDKPFSLDEAREELRGRIKSLVEEMDPEGPWFLGSTLSLVDVCLAPWAKRLFLIDHYKEGGHGIPESGEGKDGEIWKRWKKWYDAILNRDSVKETWSADDRYIIAYKRYAEDTTNSEVGQATRSGKRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHE0</accession>
    <name>X0CHE0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short-chain dehydrogenase/reductase family 16C member 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHE0"/>
    <dbReference type="eggNOG" id="KOG1201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_5_1_1"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05339">
        <property type="entry name" value="17beta-HSDXI-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK93835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="38196" checksum="6FEAC805FD07C157" modified="2014-05-14" version="1">MPTQYPRPPQRESWFAPLSIDLFLKVLNTTLLHPFVCWIIPLCFRAQTVKWEAPPMVASIAWATIVTLFWMANVVNQRIAHGIPREVDLSEEVIVITGGASGMGLLVAEVYGMRGATVAVLDVNEMENTEARGVTYYKCDVGDKDQVAKVALEIEKDLGTPTVLINNAAIVIGKTLLDLSLDEIDKSLTTNLLGPFYCLKTFLPAIIRGGRGGTIVNVSSVIGTVGAAQLTDYAAAKAGLTAMHRSLTAELRESHPEIRTVLVTPGQVSTPLFYGVQTPNSFIAPVVEPVDVAKEIVAAIDSGKGATVAMPLYARWVDWLNVLPVGVQTIARWAAGVDRGMKTFVGREGQKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHI3</accession>
    <name>X0CHI3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHI3"/>
    <dbReference type="eggNOG" id="ENOG502RAG6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098693_0_0_1"/>
    <dbReference type="OrthoDB" id="5104920at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="248" mass="24741" checksum="2700CBDADBD13BCD" modified="2014-05-14" version="1">MKAVFGAGQQGSAAVPIISGVAALGAGVYYLGRSKPETTPEQDRRGRAEAKKAEGLSGAGIGGNAVTGGHELSHANSNRKEGTTAPPEKLPSGGVGGGVGGGGSNVRTSVEMSAKDQPGTSSTSHGSGMLGGLFGTGGSKAGDGSGKEAKDTRVASNYDGTPTKRDATKHDQHQPRVDKSGGGDDSSNKGGSSSSSKNSNDQSARQSFQGAFGQGGGDVAERGDQSQGFRDPRVASNHTETTTKKHAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIP3</accession>
    <name>X0CIP3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CST complex subunit Ten1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIP3"/>
    <dbReference type="HOGENOM" id="CLU_102601_1_0_1"/>
    <dbReference type="OrthoDB" id="5275361at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990879">
        <property type="term" value="C:CST complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016233">
        <property type="term" value="P:telomere capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024222">
        <property type="entry name" value="Ten1_fungal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12658">
        <property type="entry name" value="Ten1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14096" checksum="8D10835B21797CFF" modified="2014-05-14" version="1">MSRGPVSSQLHLLSNLPAVPIGDKVRFLGCVTSYSTSSACLFLSHLYPRDSNATAVVDVSLLLESLTAEQTRVGEFVNVIGYITEQKMTRDKKQPYQESKQVCVQAIVLWSTGPMDLQKYEKLLDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIT5</accession>
    <name>X0CIT5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_04446</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIT5"/>
    <dbReference type="eggNOG" id="KOG3017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035730_5_0_1"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002413">
        <property type="entry name" value="V5_allergen-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00838">
        <property type="entry name" value="V5ALLERGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738231" description="SCP domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="168"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK94340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="336" mass="36265" checksum="0E71D7637FF7EC80" modified="2014-05-14" version="1">MKASMFLLGASAILASASPIRNALEKREIEKREMKTEWVYEVVTVTVVAGDEPETTAPAATKPTGVVFMEAPAPKYTAPSTTKEAAKPKKVKKPVSKPSTTKEAPKVTVVTVEPQPESTKETVYESPAPVVEKPKTTVEKVVAKPTKAAEPKVEVPASGGDDLSLDGAYNTVMLAYHNIHRLNHSASALEWDDELAGYAENTANGCVFEHDMKQGNGGYGQNLASWGATSDIDGLKNKAAAGGITNQWYNNEMANWAFYGQENPPADMNIDLYGHFTQVVWKDSTKVGCATVKCPAGTVLSFPSWYTVCNYNPQGNFGGRYGDNVLKPKGEKRVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CL11</accession>
    <name>X0CL11_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein CASP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_06270</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CASP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CL11"/>
    <dbReference type="eggNOG" id="KOG0963">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016758_1_0_1"/>
    <dbReference type="OrthoDB" id="10257567at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012955">
        <property type="entry name" value="CASP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057476">
        <property type="entry name" value="Cux_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043">
        <property type="entry name" value="CCAAT DISPLACEMENT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043:SF2">
        <property type="entry name" value="HOMEOBOX PROTEIN CUT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08172">
        <property type="entry name" value="CASP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25398">
        <property type="entry name" value="CUX1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15" id="KW-0371">Homeobox</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="665"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="Cux N-terminal" evidence="14">
        <location>
            <begin position="26"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="CASP C-terminal" evidence="13">
        <location>
            <begin position="434"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="144"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="258"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="418"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="524"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK91514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="722" mass="80545" checksum="F8FE76AB7610B019" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLQ8</accession>
    <name>X0CLQ8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLQ8"/>
    <dbReference type="eggNOG" id="ENOG502STFS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142972_0_0_1"/>
    <dbReference type="OrthoDB" id="2799468at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007011">
        <property type="entry name" value="LEA_SMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04927">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP" evidence="2">
        <location>
            <begin position="73"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="113" mass="11423" checksum="E877C082736964E6" modified="2014-05-14" version="1">MAGLPTKDDIKAQAVDGRPITQAEASAIASEESALTGSGPIKGGAAATAQSLHDKQQNFLEKAGEVVRKPPTEVTKEDAAEVQRAEARAKGGPPGKGSTAADVQSVADTNTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN75</accession>
    <name>X0CN75_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03142</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN75"/>
    <dbReference type="eggNOG" id="KOG4628">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031409_1_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16473">
        <property type="entry name" value="RING-H2_RNF103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000539">
        <property type="entry name" value="Ring finger domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF434">
        <property type="entry name" value="GB|AAD18119.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="271"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="381"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="395"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK95900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="449" mass="48719" checksum="060667797A7F1C11" modified="2014-05-14" version="1">MVAVNQILTEVTHVVIRAAAAEDPSSTTSHAAAETTDSGNEKKDNGGGSNSPLLFFVALGFGVVFTNLWIIVGVKYCFRYNARNRQMRMNEDGEPITLENMPRPHRRRREKKLMTMDEVNDKFPMMKYKTWVSDRAKEGLPTTGGVSAPPTRPNSIREADGIVPDFSAKVRDSTDEQPATTVPKTNGQGETTGASNATETSAPEIAATAIVPETEKPKETPKTTEGQTSTEQTANNNNRLQRISSEETDDEDDHIDGALPPECLENPGDTCAICIDTLEDDDDVRGLTCGHAFHAVCVDPWLTSRRACCPLCKADYYVPKPRPAPDAANEAGANNGSSFDPRNNPRFGLPAAIRSAWIRGPRNGRNETPAPASRRRRTGDAAAEQEPVQQPEQAHQTPEVTQTSNGGVLSSVRGALRFGRRRQAQDNQNGSETVTPSQLEAANRTPAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP17</accession>
    <name>X0CP17_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hypoxia up-regulated 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05276</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP17"/>
    <dbReference type="eggNOG" id="KOG0104">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005965_5_0_1"/>
    <dbReference type="OrthoDB" id="10262720at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034663">
        <property type="term" value="C:endoplasmic reticulum chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10230">
        <property type="entry name" value="ASKHA_NBD_HSP70_HYOU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000039">
        <property type="entry name" value="Hsp70 family chaperone Lhs1/Orp150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF3">
        <property type="entry name" value="HYPOXIA UP-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937801" evidence="5">
        <location>
            <begin position="25"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="590"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="798"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="921"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="590"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="612"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="806"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="843"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="923"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="964"/>
            <end position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK93058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1007" mass="110193" checksum="77E0B881C6749D76" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR92</accession>
    <name>X0CR92_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05511</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR92"/>
    <dbReference type="HOGENOM" id="CLU_383111_0_0_1"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="100"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK93394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="722" mass="81297" checksum="1D86DBF5D7DDA633" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS06</accession>
    <name>X0CS06_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ca3427-like PBP 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02482</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein SsuA/TauA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS06"/>
    <dbReference type="eggNOG" id="ENOG502QRHZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061316_1_0_1"/>
    <dbReference type="OrthoDB" id="1363at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd13637">
        <property type="entry name" value="PBP2_Ca3427_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054364">
        <property type="entry name" value="Ca3427-like_PBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30024">
        <property type="entry name" value="ALIPHATIC SULFONATES-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30024:SF47">
        <property type="entry name" value="TAURINE-BINDING PERIPLASMIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22384">
        <property type="entry name" value="PBP2_Ca3427_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ca3427-like PBP 2" evidence="4">
        <location>
            <begin position="88"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK97205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="297" mass="32428" checksum="F817A0F52942A6E6" modified="2014-05-14" version="1">MSSPLRIGYVPEHFSTPLYFAQKHFGLDAELIPFPSGTGHMVTAIRAGEIDVAVGLTEGWIAGLGKEGIEGDGGYRLVGTYVETPLCWAISTGAKRPEITSVDSLKGGKIGVSRIGSGSYVMGFVLADQQGWLTPGAAEKPFSDTVVLNNFENLRNAVNSGEADFFMWEHFTSKKFYDSGEIRRVGEIYTPWSSWKIVASTKLTQNGLDARVKDLFGKLDQGIKHFNDNQEEAVAYISSSLGYTEPDAREWLKTVRFPTKTEGVRAEVVQNTVSILRKAGVLAEGKGMEPQAMVFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSB2</accession>
    <name>X0CSB2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylinositol glycan, class Q</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSB2"/>
    <dbReference type="HOGENOM" id="CLU_007914_2_0_1"/>
    <dbReference type="OrthoDB" id="70250at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007720">
        <property type="entry name" value="PigQ/GPI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21329:SF3">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21329">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05024">
        <property type="entry name" value="Gpi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="473"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="510"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="709" mass="81317" checksum="D99B17BDE6B3D680" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT64</accession>
    <name>X0CT64_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BRO domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_04270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT64"/>
    <dbReference type="eggNOG" id="KOG2220">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003661_0_0_1"/>
    <dbReference type="OrthoDB" id="2141925at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09242">
        <property type="entry name" value="BRO1_ScBro1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09237">
        <property type="entry name" value="V_ScBro1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.560">
        <property type="entry name" value="alix/aip1 in complex with the ypdl late domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.50">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025304">
        <property type="entry name" value="ALIX_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF30">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13949">
        <property type="entry name" value="ALIX_LYPXL_bnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="7">
        <location>
            <begin position="5"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="755"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="772"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="792"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="808"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="833"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="848"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="863"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="905"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="933"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="949"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="965"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00041284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK94069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="994" mass="111702" checksum="D5A2F2AF392164EA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTH2</accession>
    <name>X0CTH2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THUMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTH2"/>
    <dbReference type="eggNOG" id="KOG3943">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039352_2_0_1"/>
    <dbReference type="OrthoDB" id="367221at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11717">
        <property type="entry name" value="THUMP_THUMPD1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2300.10:FF:000001">
        <property type="entry name" value="THUMP domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2300.10">
        <property type="entry name" value="THUMP superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040183">
        <property type="entry name" value="THUMPD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452">
        <property type="entry name" value="THUMP DOMAIN CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452:SF10">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143437">
        <property type="entry name" value="THUMP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="THUMP" evidence="3">
        <location>
            <begin position="170"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK97725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="324" mass="35443" checksum="5F16ACD0A5187C94" modified="2014-05-14" version="1">MSDGAGKRKQGPGGNGPATKKSKGGSGGKWQTPHQKARKTEQAELGRTLEVNDAGIWVTYARGMKGKAITEFKNLCNEYGESLFGVKPPNEDGDNDEDDEDAGDIEASIEKELASMAQPKPKTKQTFTPIGTGLDCVFFMKTVKPIEPLKLVTKACQDAKDCPDPMQRKTKYINRLTPIFDTDKATDKGIERVARTVMESHFELKSESGEDASAEPATSEQDGEGSAACTYAIRYNIRNHTAFKSSEVIKKIADLVSPKHKVNLTSPDKVVLVEIFQTFCGVSVVDGKESEELKRYNLNELYKVALEDKQQKGKPEGEGVAEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUB7</accession>
    <name>X0CUB7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUB7"/>
    <dbReference type="eggNOG" id="ENOG502SPJH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_31_4_1"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="39308" checksum="59A1C5CB34B01FB7" modified="2014-05-14" version="1">MARGVRNKAQLGTYYRTATGPRSVPLTDPQGHRLRWPIDIGGVHVYSRDAESVIFVPSSRFWIENEADDPDALWREDTEAFDCFKTSYAYNMIGQEHPRIVPVIGQDAWTGLPILKKPSYGSLWTFIQNYGSQVYTAQADAAPPTSRIKPELRPLAYQWSLQLLSGLSLIHSRGIAYGELIETNCWISAGSLSIAVAGFLGSDFTDPSNGWNFPGSFFSGIEFSPEYLPLSRAVRVPTSKTDMFMFGRLVYQIMTSELPGDGIGSDWGETERLMAEEDWMPDLEDEFMGKIVHKCWRLEYEDVEELQSEVQAFVEAHGWSIRGDELEGFDAHSIHRELEANFVPEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUN9</accession>
    <name>X0CUN9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUN9"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051604">
        <property type="entry name" value="Ergot_Alk_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162:SF1">
        <property type="entry name" value="PRESTALK A DIFFERENTIATION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="10"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="319" mass="35708" checksum="89AB63832A050EF9" modified="2014-05-14" version="1">MSRHITVIPASTKAGRETIRTLLESESKPTIRAVYRDTSKAPPEFLKHSNFEAVKGDIGDGDSLDFTGSNTVFYIPPPTYDGTDTGDWATRAGTNVKKALEKANIQRLLILSAIGAHNSSGIGVLRVNYISDELLKDSVPEVSIVRPTYFHEDWAHLLDAAKEENPTIYSWVTPIDYKIPMVCKTSKPSRKRKENHTNLYSKVGLKDVAENCADALLAETAKPSPHYFNVFGPRAYGSLDLKEAVEEITGKKNELKLVEKDQLLDYWKQIVPEFYAEEFKEMTTCGLADGIIAKNFVYDENTVRGKVELVDALRSLYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-05-29" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVS9</accession>
    <name>X0CVS9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DHHA2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_03982</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVS9"/>
    <dbReference type="eggNOG" id="KOG4129">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019358_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="entry name" value="DHHA2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF39">
        <property type="entry name" value="EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01131">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA2" evidence="5">
        <location>
            <begin position="241"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK95408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="394" mass="44009" checksum="E40B8EC29A0B398E" modified="2014-05-14" version="1">MAISVNMASRLSLGGFLAKARAALTAPAAQRKGPLTFVVGNESADLDSLCSALVYAYMRTHTPPHTLHIPLSNLPRDDLALRTEMSAVLKHAGLTLKDLLTLSELPDLKPEETHWLLVDHNSLTGPLKKFSDRVTGCVDHHADENVIGKDADPRVVEPCGSCMSLVVDETRKTWEEISHQDPEDSDAATENDKLTRLALAPIISDTINLTAKEKVREKDSKAVEFLEGRIHDKSFNRTAYFDEISAVKEDISDLSFRDILRKDYKEWDGSGLKLGISCVVQDFNYLVDKAGASEPLIDAFEDWAKERELDVASIMTTSHPNGEFQRHLLVWGVTDQGREAVDRFVQAGDKLKLETWKEGELDHHGHKRFAWRQKELAASRKQVAPLLREALKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWI9</accession>
    <name>X0CWI9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWI9"/>
    <dbReference type="HOGENOM" id="CLU_2109112_0_0_1"/>
    <dbReference type="OrthoDB" id="4993415at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937268" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12491" checksum="3CB224870B7B9BD6" modified="2014-05-14" version="1">MVLSMVLHSIIVVSFLTCPRISVPLATSTPEKSTPRCDTAAQPRPWLGLNLVLLRSAPLANRFAVLCTPPSWALHLACLLPTILSCIPGNSMHVYPRLCIKLLGILTLPVLPSLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXH9</accession>
    <name>X0CXH9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein bL27m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_04134</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXH9"/>
    <dbReference type="SMR" id="X0CXH9"/>
    <dbReference type="eggNOG" id="KOG4600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062495_0_0_1"/>
    <dbReference type="OrthoDB" id="1867012at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000042">
        <property type="entry name" value="50S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="228"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK95579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="268" mass="30813" checksum="2D9904041C9A5796" modified="2014-05-14" version="1">MRFLTMQRPILAAVASLARPAFTPVTPLGVQLANSLVQGHRFASVKSQGAYKKKPKRGIPKKLGAKRTGDQFVIPGNILYKQRGTHWWPGENCIMGRDHTIHAMATGYVKYYRDPSLHPDRKYIGVVFDKNDTLPYPAHAQRKRKLNMTAFPIKEVAAQPEISPSGIPFQVNRVEAGEPDRLLKLRKDYSYREDNWAIGKLAKTTGLKTKRFRTRKQWFRHRRWRRERELEGQRKAEQKRAESGGEIKAVKMLSQKQAKKAKKASKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYW9</accession>
    <name>X0CYW9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bacterial surface antigen (D15) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_01894</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAM50/omp85 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYW9"/>
    <dbReference type="eggNOG" id="KOG2602">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014798_3_1_1"/>
    <dbReference type="OrthoDB" id="1724197at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.50:FF:000008">
        <property type="entry name" value="Mitochondrial outer membrane beta-barrel protein Tob55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF18">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="7">
        <location>
            <begin position="174"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK99351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="525" mass="55695" checksum="B023F17651BB1B4E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ57</accession>
    <name>X0CZ57_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_01970</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ57"/>
    <dbReference type="HOGENOM" id="CLU_028200_3_7_1"/>
    <dbReference type="OrthoDB" id="5429740at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="3"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK99446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="313" mass="34246" checksum="93362B039A730A75" modified="2014-05-14" version="1">MSVYWGNGKHFDVLSLEQKQNTIKWMMAAYVPGIETLGFPKLAVIALLARLLMPGKIHLVVLWSMGIICCLSLTAMVTTLLLQCSPPRALWTLTMPRDCLAPSKLEGLAFWASSISAFLDFYLAVYPAITLWKLLMPLKKKLILSLALGMGVVCGAIGIVKATGVPTLASQDVSYDLCDPLYWTSVEGNLIIIAACIPVLQPILEMLKGRNIWSTNKGSGKHQYEDYSKQSGQQQPGIELKDKPRKKIDTYGFTIQGKEGSEENMVDSDKVSRTTSSRPESPKEGMVRTDQVTVGYDGGEGGPTSAAKRWAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0X0</accession>
    <name>X0D0X0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0X0"/>
    <dbReference type="eggNOG" id="ENOG502RA4Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125078_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="146" mass="15381" checksum="97CCAD423F7AB826" modified="2014-05-14" version="1">MSMRLILRPVVRIPLLRPQIRLATTNPTHVHPDGNLGGPGGQQPPPARPGGPEAITRNWMPIAAAAGVIAGGVYIMLPARGKSPERTLESDMVAANSTAIGYIGQPSGKPGIASHYRELRDGKEVESMKELSGRKGGGSMGPFRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1F0</accession>
    <name>X0D1F0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferroxidase</fullName>
            <ecNumber evidence="3">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_02324</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the frataxin family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="3"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1F0"/>
    <dbReference type="SMR" id="X0D1F0"/>
    <dbReference type="eggNOG" id="KOG3413">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080880_0_0_1"/>
    <dbReference type="OrthoDB" id="1897642at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034986">
        <property type="term" value="F:iron chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.920.10:FF:000004">
        <property type="entry name" value="Mitochondrial chaperone Frataxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="entry name" value="Frataxin/CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017789">
        <property type="entry name" value="Frataxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03421">
        <property type="entry name" value="FeS_CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03422">
        <property type="entry name" value="mito_frataxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="FRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821:SF2">
        <property type="entry name" value="FRATAXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="Frataxin/Nqo15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0409">Iron storage</keyword>
    <keyword evidence="6" id="KW-0410">Iron transport</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK96949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="203" mass="22703" checksum="AAA0238B641F33EC" modified="2014-05-14" version="1">MSRQIAFQASRLASRAIRSSTPICRSSFRIAPAITHLSIRSTLSQKCFSTTVSIKRGIMPDTENPAKPLNEAEEIHQNAVVADITEQEYHDLADEYLDNVVGKFEELQDQREDIDVDFSAGVLSISWPDKGTYIINKQPPNKQIWLSSPISGPKRYDWCLIGEGQNEKEGTAVGDWIYVRDGSSLNQVFSEELGVDIDVPSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1L2</accession>
    <name>X0D1L2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein NLRC3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1L2"/>
    <dbReference type="eggNOG" id="KOG4308">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027887_0_0_1"/>
    <dbReference type="OrthoDB" id="333024at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF16">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="683" mass="74896" checksum="28A7B0E677A89874" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0D306</accession>
    <name>X0D306_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diphthamide biosynthesis protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_00785</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DPH4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D306"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_7_0_1"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF46">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="J" evidence="12">
        <location>
            <begin position="8"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DPH-type MB" evidence="13">
        <location>
            <begin position="97"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXL00777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="178" mass="20021" checksum="6440E517947E0955" modified="2014-05-14" version="1">MASPEVATHYQVLNLTPTLLDTQHDSTPLIKRAYHRALLRNHPDKVTNSDPSSVCFTVDQITTALTILSDPSCRAAYDAALRVSRPSEKRDGSFQIGVESVDLDDLAFDEDQECWYRPCRCGNEHSYEFCEADLEEVSDEGELVVGCLDCSLWLRVHFAVIEDEQESHPSNKTSKDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0D354</accession>
    <name>X0D354_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D354"/>
    <dbReference type="eggNOG" id="ENOG502RS5Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021699_0_0_1"/>
    <dbReference type="OrthoDB" id="4850804at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="373"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="432"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK98008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="685" mass="74052" checksum="FD47DBBAA85B258A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0D357</accession>
    <name>X0D357_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Bicarbonate transporter-like transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_00818</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anion exchanger (TC 2.A.31) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D357"/>
    <dbReference type="eggNOG" id="KOG1172">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002289_7_1_1"/>
    <dbReference type="OrthoDB" id="1735926at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080139">
        <property type="term" value="F:borate efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005452">
        <property type="term" value="F:solute:inorganic anion antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050801">
        <property type="term" value="P:monoatomic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.570:FF:000003">
        <property type="entry name" value="Anion exchange family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.570">
        <property type="entry name" value="Helical hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011531">
        <property type="entry name" value="HCO3_transpt-like_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003020">
        <property type="entry name" value="HCO3_transpt_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453">
        <property type="entry name" value="ANION EXCHANGE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453:SF82">
        <property type="entry name" value="BORON TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00955">
        <property type="entry name" value="HCO3_cotransp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="9">
        <location>
            <begin position="30"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="9">
        <location>
            <begin position="201"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="555"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="594"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXL00847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="609" mass="67831" checksum="EF8BDC7E6E136F44" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0D386</accession>
    <name>X0D386_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone acetyltransferase type B subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_00837</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D386"/>
    <dbReference type="eggNOG" id="KOG0264">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020445_3_1_1"/>
    <dbReference type="OrthoDB" id="427795at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="8">
        <location>
            <begin position="30"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="188"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="285"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="329"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXL00877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="439" mass="48889" checksum="6E1A136C56CF843B" modified="2014-05-14" version="1">MAPAQSAERDVDIEMTHEDDDDQGERMINEEYKTWKKNSPFLYDMILGTALTWPTLTVQWFPDVKEPEGKNYSVHRLLLGTHTSDESPNFLQIANVQIPKAVAPNPKDYDEERGEIGGYGKPGDVAAIKCEIVQKIEHPGEVNKARYQPQNPDIIATLCVDGKILIFDRTKHPLQPTSLGKVNAQIELVGHKAEGFGLNWNPHEEGCLASGSEDTTMCLWDLKTLKGDSRILNPSRKYTHHTQIVNDVQYHPISKNFIGSVSDDQTLQIVDVRHSETAKAAVVAKRGHLDAINALAFNPNSEVLVATASADKTIGIWDLRNVKEKVHTLEGHNDAVTSLAWHPTEAGILGSASYDRRIIFWDLSRVGEEVLPDDQDDGPPELLFMHGGHTNHLADFSWNLNEPWLVASAAEDNLLQIWKVAESIVGKDDGDLPVDELDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3M7</accession>
    <name>X0D3M7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="3 12">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_02805</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="3 12"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3M7"/>
    <dbReference type="SMR" id="X0D3M7"/>
    <dbReference type="eggNOG" id="KOG0660">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0075018">
        <property type="term" value="P:positive regulation of appressorium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07849">
        <property type="entry name" value="STKc_ERK1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000040">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000073">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK97714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="355" mass="41193" checksum="67C801A85CD20E16" modified="2014-05-14" version="1">MSRSNPPNAAGSRKISFNVSEQYDIQDVVGEGAYGVVCSAIHKPSGQKVAIKKITPFDHSMFCLRTLREMKLLRYFNHENIISILDIQKPRNYESFNEVYLIQELMETDMHRVIRTQDLSDDHCQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNANCDLKVCDFGLARSAASQEDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDVWSVGCILAEMLSGKPLFPGKDYHHQLTLILDVLGTPTMEDYYGIKSRRAREYIRSLPFKKKVPFRTLFPKTSDLALDLLEKLLAFNPVKRITVEEALKHPYLEPYHDPEDEPTAPPIPEEFFDFDKHKDNLSKEQLKQLIYQEIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5J7</accession>
    <name>X0D5J7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5J7"/>
    <dbReference type="eggNOG" id="ENOG502T630">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1094327_0_0_1"/>
    <dbReference type="OrthoDB" id="5092251at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="17"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK98404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="254" mass="28615" checksum="8039B7CBC4330DE0" modified="2014-05-14" version="1">MAEAMFAQQIAGMVAELGDLRKSDAAQKNEIENLRAQNDFHANEAQMLRDLRILYEAKLEQKDSEILGLHVLLDKVKVDADIYRDDLSELRKQLKDLQAKYESSQKQVCASEAKLTRRNLQVANLIYALRRKVSTNRISVVALRAAYKIIPSLEQKAQCKRILSMARKLPHKTGIESEMKECLGDAGLLISFDKNGAMVLRQSVEVVKVPVDGSKELDESIIIVEKDADNNGDYACDQHSQQNVKKDEDVQMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6F7</accession>
    <name>X0D6F7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Aspartate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="4">1.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_01516</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the NADPH-dependent formation of L-aspartate 4-semialdehyde (L-ASA) by the reductive dephosphorylation of 4-phospho-L-aspartate. Mediates the second step in the biosynthesis of amino acids that derive from aspartate (the aspartate family of amino acids), including methioinine and threonine, the latter of which is a precursor to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-aspartate 4-semialdehyde + phosphate + NADP(+) = 4-phospho-L-aspartate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:24286"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="4"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6F7"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18130">
        <property type="entry name" value="ASADH_C_arch_fung_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02315">
        <property type="entry name" value="ScASADH_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000200">
        <property type="entry name" value="Aspartate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000016">
        <property type="entry name" value="Probable aspartate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051823">
        <property type="entry name" value="ASADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005676">
        <property type="entry name" value="Asp_semi-ald_DH_pep-lack"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00978">
        <property type="entry name" value="asd_EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006416">
        <property type="entry name" value="PRK08664.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718:SF1">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01103">
        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdehyde dehydrogenase NAD-binding" evidence="15">
        <location>
            <begin position="44"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00050041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK98694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="453" mass="49593" checksum="C8715040354E5647" modified="2014-05-14" version="1">MASQFPTKKCGMSPSILPLHPISHHYLFSCPPLHTYQTSNTNSYIGVLGATGSVGQRFILLLAQHPYLTLHAIGASSRSAGKKYKDAVRWKQAAPMGDIAEMVVRECKAEEFKDCDVVFSGLDSDVAGDIELEFIKADIPVFSNAKNYRRDPLVPLVVPTVNLPHLDLIPHQRSVRSLNKGFLVCNSNCAVIGLVIPFAALQAAFGPISTVSIVTLQAVSGAGYPGVSSMDIIDNIVPFISGEEDKLETEARKILGRIDDKGTAFIEQEGLRVSATCNRVPVMDGHTACVSLSFERKPAPSAEEVRKALRDYKSEAQALGCPSAPEPAIKVFGDDEPDRPQPRLDRDLGRGYTVSVGRVREDEAGIFDIKFTALSHNSESYNFPSEDLSQTDCSSRYWCCWFVDIERRGRHSQGIHLKVQGTGGFKKQFGYIKIKIDNGICLAFSIISIPANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9U9</accession>
    <name>X0D9U9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fanconi-associated nuclease</fullName>
            <ecNumber evidence="8">3.1.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_00543</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.</text>
            <dbReference type="EC" id="3.1.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the FAN1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.1" evidence="8"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9U9"/>
    <dbReference type="eggNOG" id="KOG2143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005116_1_0_1"/>
    <dbReference type="OrthoDB" id="76364at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070336">
        <property type="term" value="F:flap-structured DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004528">
        <property type="term" value="F:phosphodiesterase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22326">
        <property type="entry name" value="FAN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1350.10:FF:000009">
        <property type="entry name" value="Fanconi-associated nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033315">
        <property type="entry name" value="Fan1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049132">
        <property type="entry name" value="FAN1-like_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049126">
        <property type="entry name" value="FAN1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049125">
        <property type="entry name" value="FAN1-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014883">
        <property type="entry name" value="VRR_NUC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15749">
        <property type="entry name" value="FANCONI-ASSOCIATED NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15749:SF4">
        <property type="entry name" value="FANCONI-ASSOCIATED NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21315">
        <property type="entry name" value="FAN1_HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21170">
        <property type="entry name" value="FAN1_TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08774">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00990">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VRR-NUC" evidence="10">
        <location>
            <begin position="719"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="292"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="312"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXL00329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="854" mass="98078" checksum="D4D3295694E1BDD2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0DAW9</accession>
    <name>X0DAW9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UvrD-like helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_00740</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DAW9"/>
    <dbReference type="eggNOG" id="ENOG502RE2I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010692_0_0_1"/>
    <dbReference type="OrthoDB" id="1470711at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070:SF66">
        <property type="entry name" value="UVRD-LIKE HELICASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="5">
        <location>
            <begin position="133"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXL00674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="741" mass="83384" checksum="022BD78AFE615E8C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0DJ57</accession>
    <name>X0DJ57_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04507</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DJ57"/>
    <dbReference type="eggNOG" id="ENOG502RN6V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2084964_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="117" mass="12873" checksum="538884513AFD009E" modified="2014-05-14" version="1">MQLLCTPPISLVRAARSLRNRLIKKTLLPARAAAASVRNSIHFSSPFSSHSHDKLKHQARPAALGTVAVLGNGLPMGMEGHAAVREGEGCSRVRKHISPFYQQWEQGSLMFQKSKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0DR05</accession>
    <name>X0DR05_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="4">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_02122</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="4"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DR05"/>
    <dbReference type="eggNOG" id="KOG2698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049768_1_3_1"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00642">
        <property type="entry name" value="GTP_cyclohydro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.10:FF:000003">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000001">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="12">
        <location>
            <begin position="132"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK96687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="312" mass="35037" checksum="B495B7624EDB5D4A" modified="2014-05-14" version="1">MPTSEDGKKRSHDVASISGSSSSSDDSRRRRRERKEKKRKNGDAIAVNGAKPSAFAQRRNSLAKASRDPRDEPIPKKRRAAPQGVPEEGAVVKTRSPSPVIDFDGLSRPSRGTRERREETEEQQAARLERMSGAVRTILECVGEDPDREGLLKTPERYAKALLFLTKGYQDNIETMVNEALFREGHSEMVIIKDIEIFSLCEHHLVPFTGKMHIGYIPNETVIGLSKLPRIAEMFARRLQIQERLTKEVAHAIMEILKPQGVAVVMESSHLCMVMRGVEKTTTSTITSCVLGCFEKKSKTRNEFLNLIGINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0DW65</accession>
    <name>X0DW65_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DW65"/>
    <dbReference type="HOGENOM" id="CLU_2184071_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="109" mass="12298" checksum="135BFFB16C6BE94E" modified="2014-05-14" version="1">MLTSSPILIPDLINTPPVGCFNRARFTFIHHAGTRTDRSLKPAMYSAKAKAWQRLSLYSDEAKLTSHLGVMSLLATLACRRSCRSRNRREFPLYSSDRHNPHGLLGTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DZ66</accession>
    <name>X0DZ66_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DZ66"/>
    <dbReference type="HOGENOM" id="CLU_2223424_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="116" mass="13047" checksum="92C3216F60DC37E6" modified="2014-05-14" version="1">MRPIFRPAEMSTDHHRHHSVISLQHTHRSQAMEILEQPVLKTALLFHPGSSVSVPFYLTPEILVGNHSRITALESPLRFVGTRVRSGVKVWSALISPFGGSFSVRLFQVLVIQNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0E3G3</accession>
    <name>X0E3G3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA mismatch repair proteins mutS family domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_00804</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E3G3"/>
    <dbReference type="eggNOG" id="ENOG502QUUG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002472_4_0_1"/>
    <dbReference type="OrthoDB" id="2534523at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043504">
        <property type="term" value="P:mitochondrial DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001238">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000042">
        <property type="entry name" value="DNA mismatch repair protein Msh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000010">
        <property type="entry name" value="DNA mismatch repair protein Msh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF34">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="9">
        <location>
            <begin position="964"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="108"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="705"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXL00813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1083" mass="118187" checksum="A3B58F778A2967E3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2D5</accession>
    <name>X0B2D5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979713">
        <property type="protein sequence ID" value="EXK75916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2D5"/>
    <dbReference type="HOGENOM" id="CLU_2776045_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="69" mass="7743" checksum="CD4F3E51B52111F5" modified="2014-05-14" version="1">MSPRLSWLLLVSAIPTTPKWAMTSSEVSLVERESEYLSRRWSFPVHHSLLGIIALVVSTQLLPLSSSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B402</accession>
    <name>X0B402_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658712">
        <property type="protein sequence ID" value="EXK76486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B402"/>
    <dbReference type="HOGENOM" id="CLU_162145_0_0_1"/>
    <dbReference type="OrthoDB" id="103349at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="86" mass="10178" checksum="5FCAB0A5A0F9BACE" modified="2014-05-14" version="1">MLSVTSADAPWRLVIPLDRASQWRFTDLKNDPLELEPLERWSMEQLVGDARNIYGEDASQWVVQADAVAQWWAWERKRLWGYKTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4P0</accession>
    <name>X0B4P0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979417">
        <property type="protein sequence ID" value="EXK77105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4P0"/>
    <dbReference type="HOGENOM" id="CLU_2121224_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="114" mass="13018" checksum="D75E7F02D1D814F7" modified="2014-05-14" version="1">MPDINIHNSTPAFIGWQSNDALHSLTEPDPKYNNITLTAVKELRSESTSPPPSAVAYQQKRPRHYSHDDCDNAMLQIWAVLTTMKGRDARMEALENRIDVRRKAWKSSKSALHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0B511</accession>
    <name>X0B511_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Chitin binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_18110</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI979411">
        <property type="protein sequence ID" value="EXK77175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B511"/>
    <dbReference type="HOGENOM" id="CLU_021264_11_3_1"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-1" evidence="9">
        <location>
            <begin position="39"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="10">
        <location>
            <begin position="117"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="9">
        <location>
            <begin position="352"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="9">
        <location>
            <begin position="411"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="372"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="430"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK77175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="48910" checksum="D599E187AAE22DF5" modified="2014-05-14" version="1">MPSLVFADGFVVRRRGAEVNFGASHDDESFKQPASLQKRATCGQGVGSCSNGQCCSESGNCGTTPAYCISPQCQMAFSAGNCDGSNKPAGDTTANIARQTSDKVPYNVYITNCSTPGTVALTFDDGPYKYTDQVLNVLKENDIKATFFIVGNNLGKGQIDDESTGWPKVLRRMHSEGHQLASHSWSHEDLSAASDEIRQQQIIYNEMAFRNIFGFFPKYLRPPYGTCTRVSGCLDYVTKLGYHVVNWNLDTKDYAHDSPSEIQTSKDTFSDGVSTYAATHSYIELSHDVHQQTAYNLTAFMIKTIKDRGYRAVPVGECLGDAPENWYVDASGTTSGASTSSAAPSTPSITKDGTCGAKRGGLKCTGSMYGDCCSYNGFCGSTSGYCDGGCQSDFGKCNTWKADSALIVSDNGLCGDKYHQTCKGSRYGDCCSKYGSCGKTDAYCGSGCQSGFGTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0B586</accession>
    <name>X0B586_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_18016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979401">
        <property type="protein sequence ID" value="EXK77270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B586"/>
    <dbReference type="HOGENOM" id="CLU_036632_1_0_1"/>
    <dbReference type="OrthoDB" id="3918601at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="3">
        <location>
            <begin position="43"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK77270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="397" mass="43625" checksum="C4D2E389C7E2864C" modified="2014-05-14" version="1">MDPETSDNDGSYRFSPVTYNDHAGQLWIVTILSLIYSTLVALARLYIKYHKFGFDDIFFALAIIFHLAQSIAVFVGLSNGLGKFNSITTLEQWATSSKSTLAVGILCLLTLSLAKCSVLALIQRIIGSKPGKSGPVCIGLMVITVVWGVGSCLAWLVNCRADSLLTLDNVKQCPHQNTRWAVITAMDILTEILTWLLVLQLSWSVNISYIRKCQVVMAFSFRIPLIALSAVHLAYTATYPASLEPQFAVTKALLCQQIMVAWSLISATVPNLKNFLKSFSMGMGFPASFNLSISRSSNVYALQSLRNNSSGVTSSAAMATGVKSTFDSAAHSQPHSWRPDEVSTQTTTSRDTGSNSWDHISEEGRNSRAGSQEMIINKEVTWKVTYEDNRCSRQCCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0B874</accession>
    <name>X0B874_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Up-regulated during septation protein 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16992</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658528">
        <property type="protein sequence ID" value="EXK78335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B874"/>
    <dbReference type="HOGENOM" id="CLU_013725_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029191">
        <property type="entry name" value="Uds1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15456">
        <property type="entry name" value="Uds1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Up-regulated during septation protein 1" evidence="3">
        <location>
            <begin position="262"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="335"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="440" mass="49005" checksum="84E1FB9791902E57" modified="2014-05-14" version="1">MQQSEQPKKYQLSPKASSLLVPDNITRDVGGEKAIPTPWAPRSDKTDKHLGSDGLKKRLNNHGLVRRRNTGRIETGPMTTVQEMAMDSPTIPGCLLLHERSSVPSDLSRKHQLTHTFNFVPGNNEDREPQSACNKVPQLHDTAFSSDQCNFLRHVTYPCLKSSNGISDCVPQAMGWALYSPNVATEESSAFRGHQKGNSGSSGIVSKGRPRKWPDLRTRNYPILQWTEPKKAKILEPEAFEQLPSGWTQVNALGQFKHSELSLLQKQAIDQVGQFEVLKAADVKILSEELHHLDERTEYLRRVYGAFRHSRRNLHTRIYQYLSSPHSAKFSHKSIAAQKEALAELDDSIDDWMNKLAQVENRRSRVHQKLLEHTAAVACLTIGRSSTTPESKTKATALGAGNTSTASRIPLHEAFTSAHTASSSTSSQRAVVRVLSTIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8B7</accession>
    <name>X0B8B7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979369">
        <property type="protein sequence ID" value="EXK78021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8B7"/>
    <dbReference type="HOGENOM" id="CLU_125595_2_0_1"/>
    <dbReference type="OrthoDB" id="2251794at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935572" evidence="1">
        <location>
            <begin position="19"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="140" mass="15150" checksum="80A5A63CAFF75C99" modified="2014-05-14" version="1">MKFSAVVVLLLPLSGVLASPVADSGPVGIGRDEHATGTEPLSVDQSEADLVGRDLFARSTRKCKIVNVSNRAFCRSGPGTNYPIKYSVYKGQEYKFDCYKKGTCHEGNCTWDRLPHAEGYCYVSGAYTDGRCTKAALGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8L4</accession>
    <name>X0B8L4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DOPA 4,5-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979359">
        <property type="protein sequence ID" value="EXK78490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8L4"/>
    <dbReference type="eggNOG" id="ENOG502S93P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090062_0_1_1"/>
    <dbReference type="OrthoDB" id="9970095at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1240">
        <property type="entry name" value="DOPA-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023389">
        <property type="entry name" value="DOPA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014980">
        <property type="entry name" value="DOPA_dioxygen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423:SF2">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08883">
        <property type="entry name" value="DOPA_dioxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143410">
        <property type="entry name" value="DOPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="179" mass="20734" checksum="9851F4E7D3A58101" modified="2014-05-14" version="1">MGDASVFKYPSPLTGYENAPPLPDEKAADGKSYVNPPSEKLSEAYEKFIDPLDRSDRGGFDIHIYYLQTNETQVKYAKELWERIRREFPELRIYKLWERPIGPHPIAMFEVNVFSPAQFGAFVAWLAIWRGPLSALVHPNVIPEKGVNRWASMKRDHLERAIWMGERLPLDASLFNRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BA48</accession>
    <name>X0BA48_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16687</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658511">
        <property type="protein sequence ID" value="EXK78651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BA48"/>
    <dbReference type="HOGENOM" id="CLU_994135_0_0_1"/>
    <dbReference type="OrthoDB" id="2378324at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051059">
        <property type="term" value="F:NF-kappaB binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071356">
        <property type="term" value="P:cellular response to tumor necrosis factor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051070">
        <property type="entry name" value="NF-kappa-B_inhibitor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46680">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46680:SF3">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR CACTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="145"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="179"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="214"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="280" mass="30902" checksum="58177551D70FCC9A" modified="2014-05-14" version="1">MVLCILYHAAMAADAGYSMTMPMAVEALNAWKIYRQDEDGKPFEPVEVVQGCRGLIIWGENDRSFRIRSPLLGDYLTYLWFASGFLGLGLAKAVPEAFVQDFRQLSSRRGSIESYQQAAEANPFENETSYDELEEYHKRWHCFTTGYSPLHLAAHLSPPAYLIDVLVVFGEDLEARDCLGRTALHLAAETEGDISIMESFVEAGANVFAKDDDAGDTPLVNAVIHGDPASVKFLLGNGAEISELNEGILKQCRQENPDVAVYLQELGIDVLAADETEAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAR0</accession>
    <name>X0BAR0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979714">
        <property type="protein sequence ID" value="EXK75913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAR0"/>
    <dbReference type="HOGENOM" id="CLU_2904299_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="62" mass="7082" checksum="2E01BCB9EB09E22E" modified="2014-05-14" version="1">MGHRLTSGHYTTSSNDQGKHRLQNGFWNRSHRPTKDYSGPHRSHATDRSSIPLAGCFLHRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAX3</accession>
    <name>X0BAX3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979349">
        <property type="protein sequence ID" value="EXK79295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAX3"/>
    <dbReference type="HOGENOM" id="CLU_2346865_0_0_1"/>
    <dbReference type="OrthoDB" id="2873061at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587:SF3">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="100" mass="11005" checksum="E4054E8AE4B975D7" modified="2014-05-14" version="1">MATEETIQNAGSNVGDQSDNSENNTHQMTQGSQNNQVDRSNTGSQEALNQPQNQQPIQPASQETEKKSSAPRVRLDMDLDVELQLKAKIQGDLELAILEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB02</accession>
    <name>X0BB02_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658490">
        <property type="protein sequence ID" value="EXK78956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB02"/>
    <dbReference type="eggNOG" id="ENOG502RKKF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092864_0_0_1"/>
    <dbReference type="OrthoDB" id="3558762at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="262" mass="29984" checksum="2A4E408E7C52D7FC" modified="2014-05-14" version="1">MCSSCNAKGYFSSRCINGRGPVVDRRPVELVEAPRLAQSYSSGHASQEISRLPSHLVAQRPSSSRTGSSSIRSSVRPQVNVQYEPSILSVDSEQKLVDSLMSLRFEIKDMGERIEYLLDLRKRLSHRQKKVNPDEYKQALNSPSMLILYEAYKEASHYRDQCRTAVNQRMAQYHNKYSLASEEDLMEVYALQEKWVRAAVNAAEQRLNYLQQFPFAYKDKEAIRGHIIAANDAMNGAVKALEEVEYNKRILFAKMSRQGPWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBA3</accession>
    <name>X0BBA3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979848">
        <property type="protein sequence ID" value="EXK75749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBA3"/>
    <dbReference type="HOGENOM" id="CLU_3207687_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="45" mass="4628" checksum="BA5A630BF9A4E496" modified="2014-05-14" version="1">MAGISPSNPPQSPVHNAAEAATNTAPVEVDTRPVNDSDSTFSSEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBW2</accession>
    <name>X0BBW2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658475">
        <property type="protein sequence ID" value="EXK79266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBW2"/>
    <dbReference type="HOGENOM" id="CLU_1129108_0_0_1"/>
    <dbReference type="OrthoDB" id="10440789at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="246" mass="26514" checksum="AC6CC44E894B42C7" modified="2014-05-14" version="1">MPPRTRSSTKLQNTQNTRKDDKDDFGGEEMEKDGKVGNIRKTQDKRSKADANNGEPVGNRENDTFMLDAEHVGIGSNIPIFNQGDQQAAAGRCTKICETIYVGGRQGDRPSSPTKEAESIHVAGYEVDANPLLQENGMSDPELDTAMLDAQDGEFGSNGITSPAGRYEQVANIMEGVEHGEGEANPPIGRAGSNNHTEGDIPVQNTIEANASARTGTETGNIDGQETARNREIRPLRPKPLIKNVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCN7</accession>
    <name>X0BCN7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_18675</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658702">
        <property type="protein sequence ID" value="EXK76588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCN7"/>
    <dbReference type="HOGENOM" id="CLU_000960_25_1_1"/>
    <dbReference type="OrthoDB" id="2587356at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF195">
        <property type="entry name" value="PEP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="510"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="24"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="552"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="552"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK76588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="583" mass="62597" checksum="739A1E644E94AF8A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE28</accession>
    <name>X0BE28_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Carboxypeptidase M14A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_15112</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Extracellular metalloprotease that contributes to pathogenicity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658446">
        <property type="protein sequence ID" value="EXK80405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE28"/>
    <dbReference type="eggNOG" id="KOG2650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019326_1_1_1"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000040">
        <property type="entry name" value="zinc carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057247">
        <property type="entry name" value="CARBOXYPEPT_ZN_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00133">
        <property type="entry name" value="CARBOXYPEPT_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0843">Virulence</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936396" description="Carboxypeptidase M14A" evidence="16">
        <location>
            <begin position="18"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="17">
        <location>
            <begin position="119"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="15">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00081330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK80405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="423" mass="47526" checksum="B91FECABBB65A9C4" modified="2014-05-14" version="1">MLFSIIYAGLLLPIVAAKVSYDGWKAFSITARPSDKDILSLLKSIDHVSLSCGQNHDVFEVAIPPGKLDAFKRLGLKTAVVSDNMGAEIAQEGSFGLYQATAKRPGANAKLPDKSYFKSYHSFEQHLQFLSDLQASFPKNSEVFTAGMTVQNREIQGIHLWGKGDKGRNPAIVWHANSHAREWISGMTVEYMAWKLVQGYQNKDRLVRDTLNNYDFYIIPIANPDGFVYTITDDRLWRKNRQKRAGQKCIGTDLNRNWPHEWDIPGGSSTDTCNETYRGMKAGDTPENKALVKHTKSVAQKNGIKSYIDFHSFSQLILLPYGYTCDTNITDIKEQMELAGGVADAIKQVNDLNFYYGPTCQTIYQTSGGSSDWVYDVAGAELAWGMELRPQRLRGNGFVLPPKQIVESGEEIWAGMRYLFENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFD7</accession>
    <name>X0BFD7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_14966</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979337">
        <property type="protein sequence ID" value="EXK80531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFD7"/>
    <dbReference type="HOGENOM" id="CLU_024655_0_0_1"/>
    <dbReference type="OrthoDB" id="5355161at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF3">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="11"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK80531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="418" mass="46730" checksum="0EEDECE514D01F20" modified="2014-05-14" version="1">MAENRNLKKRACILCTRAKRKCDRQTPSCARCTAKGFMCRYPAPRIVPSYDIIYDEHGTFETVPATTALQGVQIFEEPCLNQDQSPSDPTNPIADTLIPVSNWGSDPLPSLPWYLTTSSWNLSSVPRSECLTFEEDNLKSFIRSLQNWMKQWTSHGHCAFIHRSLYSDHMPVVIQDAYTTLAAYQTKTPANHNMALRICKERLTTLIECQSLVSVNGDTTMHLSRTQALIVYISICLFDGDINARARAEQGLDILMPWGHQLIQSASSCSGLPATWNISDRGIPVPGEPTTTTHLTPCLDGNLDSFWRSWAYAESIRRTYLIVVLLVTIYSTLKTGWSGCPGGVTFTGDEGLWDASSAHAWKRVMKGVNEKVIGFIPIFSHRMGDVLANRKPADVDDFTCTLLAATFGRERLEGWRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFS8</accession>
    <name>X0BFS8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK81020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFS8"/>
    <dbReference type="HOGENOM" id="CLU_1402501_0_0_1"/>
    <dbReference type="OrthoDB" id="10347840at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="194" mass="21502" checksum="7FDEF242006C91E6" modified="2014-05-14" version="1">MPKAETPSSTTLCIRLTYPSIILRTSARYTNMPILRDDEIAKEVEKWRLEINTLNKLFSGLILKAKLQAELVKLARGTVYFVVSGHRDNVSALSAARVAWHDQRNSSKINRNRNYIPSPGEQEGPGGGQDDNLLDALANVPEGFVWPSVNQKKIEISNIPGSHGSLGIRNLAIANGKRYGGSRVEEELKRRGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGS0</accession>
    <name>X0BGS0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Succinate--hydroxymethylglutarate CoA-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979333">
        <property type="protein sequence ID" value="EXK81340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGS0"/>
    <dbReference type="eggNOG" id="KOG3957">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033975_0_1_1"/>
    <dbReference type="OrthoDB" id="5863171at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047369">
        <property type="term" value="F:succinate-hydroxymethylglutarate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="entry name" value="formyl-coa transferase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050483">
        <property type="entry name" value="CoA-transferase_III_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207:SF3">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="434" mass="47297" checksum="12C09EBDC7515B50" modified="2014-05-14" version="1">MLTMRRRLVAPLWRSALSRRGNATAATPRLPLTGIRVLDISRVLAGPYCAQILGDLGAEVIKIEHPTRGDDTRAWGPPFAPYKDGRGGEGESAYYLSVNRNKRSVAVSFKEKEGAKLIQTLAAKADIIVENYLPGTLKKYGLDYNTLAKTNPRLIYASITGYGQTGPYSNRAGFDVMVEAEMGLMHITGPRDGPPVKVGVAVTDLTTGLYAVNSILAAVIERSHSGQGQALDVCLSDCQVATLANMAQSVLVTGKRDGGRYGTSHPSVVPYRAFRSKDGDILIGGANDRLFGVLCKCLGQEEWADDERFSTNSARVANRDVLERMIEDITSSKLSKEWLDIFEGTGLAYAKINDIKDTLEHSHVVARDMIKEIKHPACGQLKVLNSPVKYSRTQPSIRTPPPLLGEHTDQVLRDVLGLDPAEIKRLRENKAVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGX6</accession>
    <name>X0BGX6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_17214</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979367">
        <property type="protein sequence ID" value="EXK78103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGX6"/>
    <dbReference type="eggNOG" id="ENOG502RNNV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_10_0_1"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF92">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="27"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK78103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="321" mass="36398" checksum="6D82C2045FF8AB4F" modified="2014-05-14" version="1">MPAGPSGVVVLTVIYVLISLSAIIIGARIYLRLAMQKQRLVTADWLRISAWCTAFVTGFFDILYAKEGVLHPGINYTLSNWDAPLEQQIRVRKYNWVNPFPFYTTFYLCKASLLVIYLQLFPPFMVIRRLMVWIVVVYCVCAYIVTISLQLFLCYPIQRNWSVTKSEEACEITTILLLFQINWVLHFVGSIARNFLSSVLYHPQSQYAKEGQKLWCSLDVYIGLVICCIPALRPYLHRKGVNYNIQESGRPSKSGHAIRRTGQSGFEEIIEGSGLEGDCRNDSWSASHSCEITAELSDKKGNGSDIELVSVEINKSSADRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIC6</accession>
    <name>X0BIC6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mycophenolic acid synthesis protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13684</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658419">
        <property type="protein sequence ID" value="EXK81925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIC6"/>
    <dbReference type="HOGENOM" id="CLU_039076_0_0_1"/>
    <dbReference type="OrthoDB" id="545169at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046366">
        <property type="entry name" value="MPAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124:SF4">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="45652" checksum="A6471596CBEB761B" modified="2014-05-14" version="1">MLFMALFALAAYATRVRFLRYRRKIAIEANFTSGKRSLSGMTTKEAHDIIAQLQLLEFPYAFNKARKIALLKAGGIPTMSKLFAVTGQNTRRNAGKRSVDTEVLLRESQSQPRDSERYAMAVARMNYLHARYRRVNKITDLDLLHTLGDGLAEIFKVVHREEWRDLTDVEKCAIGLFHKNLGDDMEIPFDPLPSSSQGWRNGLEFAKELEAWTLRYEQEVARPTATNDQYVRVYVDSAFSRMPAFVGKTLRKYLGENLDDIMRESLCIESPGSFLSALIKVARAIRIMYLRHLALPRTRPVEIVANGPNPSTGLFNFPQKVFQPWYVKPTFWSTWGPRAFLLRALGGKVPGSQGERFHPQGYNLMTIGPEPQKGKGLEEMATTAGIIKAKGVATCPFSQARVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIU4</accession>
    <name>X0BIU4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">20beta-hydroxysteroid dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979330">
        <property type="protein sequence ID" value="EXK82095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIU4"/>
    <dbReference type="eggNOG" id="KOG1210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_3_1"/>
    <dbReference type="OrthoDB" id="5307821at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF7">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE (AFU_ORTHOLOGUE AFUA_2G00830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK82095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="30559" checksum="C8FEAAEE927AF57D" modified="2014-05-14" version="1">MSPADVFSPGSTALITGAGSGIGLAIAKTCRSKGLRTLLVDNNEEALEALIKTHFPNDSNVVTSKVDVSSASDWQALKKLALDKFGSIEFLVLNAGRGLRGTWGDDNYFRDTLETNLFGVIHGINTFLPVVQDAAKSKPTSIVITGSKQGITNPPGNPAYNASKAAVKTLAEHLSWDLKDTSTSVHLLVPGWTYTGLTRATPDGVKPAGAWTAEQVADYLYEKMGKNEFYIICPDNDVTEEQDKKRMTWAAGDVVQRRPPLSRWRGDWKQEAEEAMAKMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BL44</accession>
    <name>X0BL44_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15802</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979344">
        <property type="protein sequence ID" value="EXK79618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BL44"/>
    <dbReference type="eggNOG" id="ENOG502RMMS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077714_0_0_1"/>
    <dbReference type="OrthoDB" id="5101337at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="251" mass="26577" checksum="8A563355C596E248" modified="2014-05-14" version="1">MLSGDADISVVFGFFCANSGAYLDSVELKPAAVIPNTDTTTVATNSETSMIITTTQETTMATSTEGSTIATETATTTTAADADPTPLLINGNFDLDTTEPWLSTHSESVDRDTNSPFEGPASGRLLFGVDGGLAYNNYFYQKIDTKDLKAASYRLSGLVRVDYYNPSISGDGCNSMAVGCTLGNPNNLNRVPGSTVMGTPSVAVDNWFPLDTTCTLTEEMLSQYDYVSVTFGFSCAEVGANLDAVAFQEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM66</accession>
    <name>X0BM66_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LisH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_12778</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM66"/>
    <dbReference type="HOGENOM" id="CLU_039195_0_0_1"/>
    <dbReference type="OrthoDB" id="5600002at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610:SF12">
        <property type="entry name" value="SEQUENCE-SPECIFIC SINGLE-STRANDED DNA-BINDING PROTEIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610">
        <property type="entry name" value="SINGLE STRANDED DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="191"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK82946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="33026" checksum="1CBA023E3AFF8C77" modified="2014-05-14" version="1">MANLKAKTGHPHDASKHLQENYNKQTQLNTYIYEYFLHNSMFKCAQSILKADSDVRVQRHSPGSDHHDKGLRLKNALRNKTIDSRLDSTHSNLLPAPNVPNLSPDSCFLYEWFCLFWAMFNAQKNENRRIEACQYACHIQQQNWPKWNVSWPQTQSSLLLLRAPGSATHNAFYNSGEVGVGSMTPAISGVRDCGSSNSASQKSHVQLTSMKQQNENQMTARQDRSNLYRNDGISGGRGGQRPRQNSKLFQQPGLQTSRPGALPDTTKQVKLGTQPMNNISVFSHLLFRISPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM75</accession>
    <name>X0BM75_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM75"/>
    <dbReference type="HOGENOM" id="CLU_1151847_0_0_1"/>
    <dbReference type="OrthoDB" id="5138418at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33303:SF2">
        <property type="entry name" value="COA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33303">
        <property type="entry name" value="CYTOPLASMIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="1">
        <location>
            <begin position="172"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="241" mass="26343" checksum="956D95EDCA8C9512" modified="2014-05-14" version="1">MMSTEANVRNFFASSASAAVGASSNPANFGHRGRILSVRGISIPIMTCQSLPLIRGRQLFLLWKRIIPLSPASRRFPTPNRRPSQSSLPSATLKVLQEAKELRIPSAWLQPGSFDDDVLKFANEQGGFNAVVAGDAGRISKGVAEAINTLAQQENLFKIEVEAAQRPRDAVEDLLRQMVAQLGGINTRLRTFEGSVNRMEATVAGQGERLDNIDERLDSIDGHLANLLVPSTFPARLYQHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP56</accession>
    <name>X0BP56_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658438">
        <property type="protein sequence ID" value="EXK80663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP56"/>
    <dbReference type="HOGENOM" id="CLU_017584_4_4_1"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43510">
        <property type="entry name" value="AMINOTRANSFERASE FUNCTION, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43510:SF1">
        <property type="entry name" value="AMINOTRANSFERASE FUNCTION, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="3">
        <location>
            <begin position="97"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK80663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="433" mass="47774" checksum="607AA6ABD8B675DD" modified="2014-05-14" version="1">MHRQLYISTHIITGLTREIILVFKSLLTLKRVLHCATPKAFTMHDIPEFELDQVARSYGPRAKIALHGSAPYALSLDNLRDLSASKLSPIDNDIPLSYAPSLGSVELRKCLAEIYSTESAPLTEDNVIITPGSIMANYLVLSTTCTKGEHVICQFPNYGPLYLLPKYFGAEVDFWVGKEERSWNPDIAELKALIKPNTKAIILTNPCNPTGTVLGQEILEQIRDLAKRHNITIFGDEVFRPLFHDDTPTPPSVISLGYANTISTGSVSKAYSLPGIRIGWIISPNTDILQRIIAARDYTTLNVSRIDDAIALFALSPDVLPKIVAQILTTQSKNIEQYDQFVTRNPDRCRWVRPRGGGTAFIHFSGSNGKSIDEVGFAEKLIEEFGVAVIPASAGFSEEGVADYKGYLRLSLGQRVEAVAEGLRAIELAIQDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPD1</accession>
    <name>X0BPD1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450, family 3, subfamily A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14781</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658437">
        <property type="protein sequence ID" value="EXK80748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPD1"/>
    <dbReference type="HOGENOM" id="CLU_001570_14_2_1"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK80748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="454" mass="51614" checksum="5A5F8950770F080F" modified="2014-05-14" version="1">MDKFTSLSYPATFTSSIATRSVSLIPFLVLSFIIVRFTWSAFKASRSPLACIPGPWYAFLTTIHLKYGFATGKIWKLVERSHKKYGPIVRLGPRQVWISDKEAMKQILLKIDLPKVAMYAEISRDRFSPGLFGEIRPVPHKRLKRFLSPAFTVAYIDNLECFFAGTIRDLLNKYETSLSKSPQSNKIEVDVMDDLHNVALDIMGECSFGRGFGQTNPAAEIEQGIREKVWKSIPRSIFDGLSKRYQSVYIKRFFRATGINIEFDWPKEMIMAIDAVVQRRRAADNATRKDLLQHLIDEGAKPDTLTTMNTRDIVDQMSEILLAGSETTSGTTACLFLELARNPGKRAKLLDSLPILDIHDEIISGKAVRNDPKYRYLNACIKETLRLHPIASEMGRRTGDQWVQLMGHNLPPHTVVSASYRDLHRNEDYFPKAMSFLPERFLEDSERGDVPAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR96</accession>
    <name>X0BR96_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR96"/>
    <dbReference type="eggNOG" id="ENOG502REG0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135736_0_0_1"/>
    <dbReference type="OrthoDB" id="5043844at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936486" evidence="1">
        <location>
            <begin position="20"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="149" mass="17134" checksum="6F82EA442170977C" modified="2014-05-14" version="1">MQTKAFLTTLLAALPAAQAFKFTGPDPSEPIDVSKEVTITWEGDIPDSLSRKFDFSWYCEPDDRNKLSSDISQLVADIYLSDHKYKFRFHNSKSMLEPFADKIATKKVFSFQAVFTDEKQDDLQLQYWSQNYTIVGLDKKEDENSEADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRI8</accession>
    <name>X0BRI8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prolyl oligopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658426">
        <property type="protein sequence ID" value="EXK81543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRI8"/>
    <dbReference type="eggNOG" id="ENOG502S4H7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107214_1_0_1"/>
    <dbReference type="OrthoDB" id="2338662at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06587">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058997">
        <property type="entry name" value="YycE-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058998">
        <property type="entry name" value="YycE-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22659">
        <property type="entry name" value="YycE-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22658">
        <property type="entry name" value="YycE-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="134" mass="15014" checksum="4D02BC9CBBEC43A4" modified="2014-05-14" version="1">MSAPIASAHLRVARPTNNIDALLPFYVDGLGFKKIGEFRDHDGFDGLMLGHEGAGYHLEFTAKRGHDAGRSPTQDNLMIFYLPKKEEFDDAVARMEKAGIVSVTSFNPYWDQCGKTFEDADGYRVVLANMKWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSH3</accession>
    <name>X0BSH3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Spore wall maturation protein DIT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSH3"/>
    <dbReference type="HOGENOM" id="CLU_038280_2_0_1"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007817">
        <property type="entry name" value="Isocyanide_synthase_DIT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37285">
        <property type="entry name" value="SPORE WALL MATURATION PROTEIN DIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37285:SF5">
        <property type="entry name" value="SPORE WALL MATURATION PROTEIN DIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05141">
        <property type="entry name" value="DIT1_PvcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="56182" checksum="6A5EFB977113BB94" modified="2014-05-14" version="1">MQIIPSYPAFANQHSMSVTSKFVSDASVQEQASICKSGADSTVRPVAGQQDTDPSVHAVSSKILDIIFEYALNKFSDSKERLEAGRPKFLSVVGKFVTTSTRVEMCLPAFPFKSANKAYKVFGILPDKAEEIALDRLNTMCIRIGEIYQPGVQCTIISDGVVYNDLLSIPDRDTWAYGQVLRELASKKGLQHISFSRIRDLVDLPLPAEMHEIAYVANATNFRRALLNRFGKDDIDIDKEIEEDPDTKMTYLGYRRFLESDLKHIFPVGNGRTANAYRRDVRYLAKQMLIRGYAFAAAVKHGFPYHLRLSIHQSTGEHKISMSLLNTKTGFTTPWHCCVALTASGEWTSAPKGEYLKDPNMKIIHENGRPSHFQEIVGSNEPHQKAETGTREVNSSENQSNAPHTELQEPVTLFLTETERERVAALARFMMSADFKQNDEIVKSGQPGMDKALDCNSNELSTMAWLKELINAVARDTGGYNEKATGVTYQEILVNGAHQLSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTK4</accession>
    <name>X0BTK4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alginate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658421">
        <property type="protein sequence ID" value="EXK81824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTK4"/>
    <dbReference type="HOGENOM" id="CLU_038125_2_0_1"/>
    <dbReference type="OrthoDB" id="5280547at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936676" description="Alginate lyase domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="44846" checksum="821D7879EF8402E8" modified="2014-05-14" version="1">MRLLTFSLLLISGVAGLVQDVPSINAAIPYVPWTEGMKRKPSDFNHPGLWHSHNDLEVMRNGVLKGLDPWKSGYEQFANSSFSQSSYKMNGPYAVISRGSISNYTSFANDARAAYQNAIMWYITKDQAHWDRSTTILDSWGTNLTNIIGTDRSLLIGIEGTLFANAAEIMRWEGGWTEVGAKWQGGQGFSIQLYWLFLRQSLIIGQANYGIASIKALMDYAVYLEDVSAYNFAIWSWKNDWCAGIDATINSKTGQNSESGRDQSHVMSGLGWLALAARTSKTQGYDLFGYGNNLLLKGAEYAAKYNLNETVPYDSKWRRCESVLVNGPWQNISEFNRGIVQEVSGVVKKAPAVWDLLYYTSEAKGLNNQWTTKAKEAYDAAGGEVVTGGDMPGFGDLLWATSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTP5</accession>
    <name>X0BTP5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_13318</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JH658415">
        <property type="protein sequence ID" value="EXK82293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTP5"/>
    <dbReference type="HOGENOM" id="CLU_431502_0_0_1"/>
    <dbReference type="OrthoDB" id="524326at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="8">
        <location>
            <begin position="458"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="385"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK82293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="765" mass="86357" checksum="E052E7EBA9D78461" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTS4</accession>
    <name>X0BTS4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658415">
        <property type="protein sequence ID" value="EXK82323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTS4"/>
    <dbReference type="eggNOG" id="ENOG502SN86">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1489083_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="181" mass="19786" checksum="6C5EAD1169977A8D" modified="2014-05-14" version="1">MRGVIREPGSIPSWSWMSVKGGIKGYVHTTPTLSMIELLESDLQWKETPLASPLTVARLTVKGKIIQATLGARSVTQESRHHVLAAPGGDEIFGEAFLDSRIPDGAEMPTVSCLFVMEVPEKKEYFTLLLTGSSGDEVGSQEKGMTRLGIGVFWTRSRFYSNRTEGDVILEKASEATVVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BU14</accession>
    <name>X0BU14_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BU14"/>
    <dbReference type="HOGENOM" id="CLU_009043_1_0_1"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053209">
        <property type="entry name" value="Gramillin-biosynth_MTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643:SF2">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="295"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="373"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="655" mass="74520" checksum="DBC3F117D761321F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWG9</accession>
    <name>X0BWG9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09802</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWG9"/>
    <dbReference type="HOGENOM" id="CLU_038958_0_0_1"/>
    <dbReference type="OrthoDB" id="5062850at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="534" mass="61329" checksum="B4EFDBC3D0E995A3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWM3</accession>
    <name>X0BWM3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12737</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWM3"/>
    <dbReference type="eggNOG" id="ENOG502SJWB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026304_1_0_1"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF16">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="540" mass="61058" checksum="6B275067FEC0884E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWR2</accession>
    <name>X0BWR2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWR2"/>
    <dbReference type="eggNOG" id="KOG1203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025711_1_0_1"/>
    <dbReference type="OrthoDB" id="10254604at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF50">
        <property type="entry name" value="UPF0659 PROTEIN YMR090W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="9"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="261" mass="28864" checksum="A6D9D2308F2EEB05" modified="2014-05-14" version="1">MSRHVLIVGGHGRIAQILTQQLLKKSWTVTSLVRSQDQVSQLNSLATPNQGNLNVLVRNLEHVHDTSQARSILDEVKPYTVVWCAGAGGEARPDRTFAIDRDAAINFIKATVQMPTVKKLLLISYINCRRERPSWWDEDAWIYAQEMQRGGLLSYCQAKLAADEILLQEASSRTDFSGISLRLGILSDEPAGLIELGKTTTSRGSVSRASVAEVIASLLEHETVQTAWLDMLDGAEDIETAVERVVNDRENAAEEGNRPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWX3</accession>
    <name>X0BWX3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWX3"/>
    <dbReference type="HOGENOM" id="CLU_002639_1_0_1"/>
    <dbReference type="OrthoDB" id="5362512at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="219"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="621" mass="70998" checksum="A906546C00688803" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYG2</accession>
    <name>X0BYG2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980076">
        <property type="protein sequence ID" value="EXK75582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYG2"/>
    <dbReference type="HOGENOM" id="CLU_3351184_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="37" mass="4266" checksum="B8F8E6C74AA792F6" modified="2014-05-14" version="1">MANFNPRRTNNSLCRLCFHVGWRSHSTHPRLNATAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYI5</accession>
    <name>X0BYI5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYI5"/>
    <dbReference type="HOGENOM" id="CLU_060360_0_0_1"/>
    <dbReference type="OrthoDB" id="194139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936814" evidence="2">
        <location>
            <begin position="23"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="313" mass="34122" checksum="C877BB68AD26ABE6" modified="2014-05-14" version="1">MMQSKFAYLALVYLGLMTLADSVTDSLLPALADDAHTRSGRWNLATAALILKGVSDIIGQFVIGYFLNTKSRHHAMNINTTSILVASLVTLLSLFYEQQWPVLVAIVGPLALGPFFASILADQSRVLPGILSGTCCLIGFGIVDSLKPPPYESNNFSHDESTSLLPNNQNDVELKTLSISATEYLSRCFGKKSLIRSSSLVFLPQVLFLMAICKSTRPLFKTYIQHRDDVSPIEAEALWLLRSVMSVLIFGIILPAIVLGTAPRISYPNSINLRVARISVLFISTGAFMIGLSGSLRSITTGLSYPKAEDITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYR7</accession>
    <name>X0BYR7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979950">
        <property type="protein sequence ID" value="EXK75662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYR7"/>
    <dbReference type="HOGENOM" id="CLU_3050412_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="54" mass="6023" checksum="FA87A65ED879473C" modified="2014-05-14" version="1">MTLLHPQSASTHLSPPPKPRNSGPRNHLNYLASTPELPYLCSPVTLPQSERFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZA3</accession>
    <name>X0BZA3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZA3"/>
    <dbReference type="eggNOG" id="ENOG502R9RD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1885945_0_0_1"/>
    <dbReference type="OrthoDB" id="5090257at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="135" mass="15907" checksum="434A5C8585B514F9" modified="2014-05-14" version="1">MDHYTNDMTCTDCIGLAASVANLEHALALTKIEMKRRELKSTAPFRFEKKDMRIMKLESYVHQAQEAEIKAAEAAYEECKRHLDILKDLDCKSLEAKIEKCAKLERDLYVTWRRVEEAKKRQLEYLVNFRYAEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZQ0</accession>
    <name>X0BZQ0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08987</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZQ0"/>
    <dbReference type="eggNOG" id="ENOG502RS7S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039412_1_0_1"/>
    <dbReference type="OrthoDB" id="3045089at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="360" mass="40066" checksum="7303D19C1DDB03E8" modified="2014-05-14" version="1">MDPLSIIASIAGIATAGTSLSKAIYHFISLTRGASREMVEIARNISDLSCILSELRHVLQESADLCSRKLLRRIKSAMRRISAIHDDIYALMDSSKGFQTFRWSLKRSEVQYKLTLIESHKTAIHLMLNVIILAATTRKEAQSQVTQSTSSSEDKQKEPESEVPLLRQQSENLAYAACHCLVDLSENQQFETSRPSKQLKTDSGSDNDDTRGQIQVREHGSSDGTGRWLFDLAFENYWNMSQGLEPELHFHGPVNGPEGPASDNQALVIRTPSELQIAIYEPGAGAALIETLLADWTCLSKEEITGKSIHKPETEQVRPGSPGSTQRDVAGIRFKDAVGRKFTFPYHLVKKWEASRIVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C008</accession>
    <name>X0C008_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_11313</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C008"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_0_1"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF15">
        <property type="entry name" value="ALPHA-GLUCOSIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="42"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK84523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="525" mass="58092" checksum="6396A52FB2712205" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C071</accession>
    <name>X0C071_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxisomal short-chain alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C071"/>
    <dbReference type="eggNOG" id="KOG1205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_8_2_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43115">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43115:SF4">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="32869" checksum="B994A1C721A3A7FD" modified="2014-05-14" version="1">MNPPTATINGITIRNHAKPYEAISPQRPELSQAGRIILVCGGSTGIGHAIARNYCIAGASAVIILGRRSDVAEEAASKLNEAYSSTKVTWRTCDLFDRGQAKQLWDDLEKDKTLVDVLIVNAVGQPELKPILEQGADRLWQDFENNVHAPLYLVERFYKQPGPTKQKFVVSVSTQDIHRWDSAPQMPGYQLTKNSFATVMQQIARDTPESSMRIISFHPSIVFTEAAKKAGYTEDTLPCTDENIPGGFAVWATSPEAQFLHGRFVWSTWDVNDVASGELRSQIDSDPWLLKVGVKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C103</accession>
    <name>X0C103_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transaldolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C103"/>
    <dbReference type="eggNOG" id="KOG2772">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047470_1_1_1"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF39">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="356" mass="39822" checksum="7C76D00EE6577B61" modified="2014-05-14" version="1">MSKVTWLDKLQQQVKIDIDCMDPEEAKRFLPFKPYDQTSNQRLVYEQIISPENRELFLKTVEEGKDEGWEVILDRMSALLCAKNMENIQGRVLLQTSAFHAYDTEKVIAQAQSYAREFEKLGISKDRICIKIPCTGPALNASPVLLREGIRTLGTSLFSVTQAIAASQAETLSISPYYNFPWYHTDREQWPNTKDPALDHPMSPRIVQIQQIYKRLREETGKTQPLLKPASFISAREAMAMAELGCDHATIPEDILLQLSLLDAEANAPPGGDSYMKNGTPSQRIAHLAQVDPLIGPDWPGLPALDINYLADNGAALTQAIAADPVTQRGLDEAIEAFKANELQIRDAIEEALKQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C133</accession>
    <name>X0C133_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08732</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C133"/>
    <dbReference type="HOGENOM" id="CLU_1277656_0_0_1"/>
    <dbReference type="OrthoDB" id="4764735at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="216" mass="24429" checksum="F41B5F659DE9E3D3" modified="2014-05-14" version="1">MPESNVSLVGNNYFLCGPYGRNLSGASDREFAKAFQHPPGVHHAFVAIGEDDCYFTKYYNERTERFTWSWSLSSYGGLDRALDSLDGDTPEFVSLGSDGYYFMRTRSGRIFWNLPDAADEFVENADPDNNGVKYVWLGTEGSYVAQKESGHSQWNLRGNYGSLEQSIRTMPRIRTLGLNLENDRSYFVVFDDGSVMCNPVGTNLTKDAFRAWARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C465</accession>
    <name>X0C465_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_10032</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK85973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C465"/>
    <dbReference type="eggNOG" id="ENOG502SMYN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027438_0_0_1"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="5">
        <location>
            <begin position="195"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="384"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK85973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="50351" checksum="5878CD6CA217FF78" modified="2014-05-14" version="1">MMEDLTPWTPKVSVSEGVTIDDLTITFRRTIRVPDNKNTSGLPPDEGIFPLFKIQDYARKLPLSMAQKGGMFIPMYQREALWIDFESRKNYAIRIHVGNVNIVSGEPKIPTLATELRRRQLLKQEKCIQDYIVVPDQKWIDGVATEPGQVRQFVAMPIATNCSVESQMNGEESTAGIQFDITRLDPLLSGPKDNINIMVKDLNGETSNYFLSRFSRVETLKLLVKAKAGIDVAYQSLVSSSQQLKNKLRLCDYNLKNGSLLHLCVRLRGGSSMTEEPEMNIASGGLIRQNIVEQPKGEYKKTSTATFNVQILNSTSFKRVTGQDPPKSPISAATYAKAGHPFFSLDEGPATISGNFSDLQSLAQLKGRPERNVGGIPILDVETKEILRAWVCKACKAKNTAVMRSCKSCKGRRPPLKKRNKIGILNPEGSKTPFRLSWEIAEELENKLTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4B9</accession>
    <name>X0C4B9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658589">
        <property type="protein sequence ID" value="EXK77607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4B9"/>
    <dbReference type="HOGENOM" id="CLU_3353506_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="37" mass="4368" checksum="1BCC07FF56284736" modified="2014-05-14" version="1" fragment="single">LKLADHASAAEDRMLNTWRWYWLAFKQVCQAESSKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4Z7</accession>
    <name>X0C4Z7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Presequence translocated-associated motor subunit PAM17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_10301</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the PAM complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the PAM17 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4Z7"/>
    <dbReference type="eggNOG" id="ENOG502S1B1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068297_0_0_1"/>
    <dbReference type="OrthoDB" id="5970083at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013875">
        <property type="entry name" value="Pam17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28021">
        <property type="entry name" value="PRESEQUENCE TRANSLOCATED-ASSOCIATED MOTOR SUBUNIT PAM17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28021:SF1">
        <property type="entry name" value="PRESEQUENCE TRANSLOCATED-ASSOCIATED MOTOR SUBUNIT PAM17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08566">
        <property type="entry name" value="Pam17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK85884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="218" mass="24333" checksum="53359BB90875C973" modified="2014-05-14" version="1">MASSLKTSVLRMPLTGLVRSSQKASFSTLRPASCLSASPFRPQCFTPVVAKTFSRAYADKPQSTELPPLDWNSFFKLRVSRRRYQLLFSITNGLFAGGAGAVFLSTGLAEPIISQIPLDPFMTLGLMTLAFSGLGWLSGPSVGNQVFYLLNRQWKKQMTQKEAQFFERIKKHRVDPTNSSASNPVPDFYGEKISSVSGYRQWLKDQKAFNKKKTANFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5X4</accession>
    <name>X0C5X4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Late sexual development protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5X4"/>
    <dbReference type="eggNOG" id="ENOG502SM3U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045147_0_0_1"/>
    <dbReference type="OrthoDB" id="5293813at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936975" description="Late sexual development protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="39124" checksum="6BA7536A2D68B2A7" modified="2014-05-14" version="1">MRFSTLFASVGLVGSAIAGIVPRSYRVPAANGFPNPDASQEKQIAIQAGGKLPGAPLPTTLGDGSTTAFQLIAFNELFETAYFCSLLYNVTNKIEGYKVEGDKFHEATHVLKTVLAQEEQHAIGALATLKSAGRFAPSPCKYQFPVDNLKDAILLAETFTAVVLGALQDANVVFASEGLPEVVRLISSVIGQEGEQNGFYRIYLGQVPSESPFLTTVPAAFAWSALQGFVVPGSCTEDIKKINLPIFPALQVNGGAIAVLDAEDQSLSFSATLEESHKGEDLYITYTTGQQLPYSVKAENVKWNGKTVKLEAEFPYHKLVAQGFTHAALTTSNNIATPDDVPNFTLAAPGLIQVKNPLDGGKGSHSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C732</accession>
    <name>X0C732_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PD-(D/E)XK nuclease-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979356">
        <property type="protein sequence ID" value="EXK78542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C732"/>
    <dbReference type="HOGENOM" id="CLU_027219_4_0_1"/>
    <dbReference type="OrthoDB" id="5244165at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046797">
        <property type="entry name" value="PDDEXK_12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20516">
        <property type="entry name" value="PDDEXK_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PD-(D/E)XK nuclease-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="160" mass="17944" checksum="1E2B00556248DC15" modified="2014-05-14" version="1">MVNFALALIPKETLQATIDKFLKTQGHDTLNQRAYTALASRPAPLFIETRTTSSTADRSKVRLGIWVAACYQRLRDANSAKDPMSIHLLQVWGNVWHVLFAADEKDKITLIGQAVRIGDTTSIVGMYQLLNALRVIGKWADTEFRTWIGDFLANIEIPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8G4</accession>
    <name>X0C8G4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABA 3 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658488">
        <property type="protein sequence ID" value="EXK79007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8G4"/>
    <dbReference type="HOGENOM" id="CLU_707921_0_0_1"/>
    <dbReference type="OrthoDB" id="2821964at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="46057" checksum="C1C689B08245FC9E" modified="2014-05-14" version="1">MSNKIEHQTAVNVSNEKWYFPQELRDGLQPFNLSSETIAETLACAWEYSRCVIPNWTSWERYLAFNRTIIIAIVAEFRGDLIPEINSKNIIGYDLDELLSTLFGGTSMREDMSREFRTFLLMSAEKSRKQRDSELFGRYLNALAKSPQWWFRLRDCDALARYTIASALACNGFSEIPFREEQLQLVAELSDTLYDAVAFYKHRAEGETNSTFGYVGSEMRVENYRDYREILWALDVKWAHDPAKRCVLNFIRPFGGPIHMMTRRYRFVEDGLMIGRPETDQVVELTRANFKLWHNVDSDIVKPDKDGHYMDTITKFDKLMLPGFCGLLESSARKHCSYCSNAVSSSSDIRRFGGVRLCDECKANWRSFMRAARARFAAAFPEIKNEVLKGWQCCGSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8R9</accession>
    <name>X0C8R9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_16265</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979351">
        <property type="protein sequence ID" value="EXK79102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8R9"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_3_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000115">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF242">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="18"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="469" mass="51832" checksum="0727D9C29C37C2E8" modified="2014-05-14" version="1">MPNYKIQEVMERSDSSRLHVVIVGAGLGGLGAAIAVRLAGHDVTVLESAPAIGEVGAGIQVLPNAARVLFSWGLEKELVKSATKPRKCNFIGWKGNHLSEMDYHGYAAASGGYPFLDFHRATLHKALLDRAHELGAKILCGSKVLSYEIAADNSHATVFLEGGQTMESDLVVGADGIASSLREQFLGRSDPPQLTGDLAYRLLLSTDEMRKDPDLRPFVEDPQVNYWVGPDKHAVNYVLKGGQLFNMVLLVPDDIPLDSGNTLKGNIEEMRAHFADWDPRIGKMLNLCDSVLKWRLCIRPGLDPTWSHPSGALTMLGDSVHATLPYLASGAGMALEDGGVLGLCLAKLTDKSPASKLKALAVYEACRRERTEMVVQRGTYNQWIYHLPDGEEQRQRDERFRQYGKWDEEWLSGENPIIPQSSETGEDPFPWRYHGVGRWLLTYDMWKDVDEKFSQLESEASGGSLRASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9X0</accession>
    <name>X0C9X0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9X0"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF35">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="38490" checksum="7B6252873D0311A8" modified="2014-05-14" version="1">MANQLHPFQSASSQMPALTLSPGQLFIQSQLCTKPQYPPKDLDLTGRTAIVTGANNGIGFACTKLLLQHKLSHLIIAVRSEEKGSAAAEQLRRTLPSSSPQIDVWKLDMASYSSIEDFAKRCETLPRIDFVFLNAGMGGTTFNLNKATGHEETMQVNFLSTMYLSVLLLPVLTSRAPAPKPSRLTIVSSGTAMHCELPEAKADHIISALDLEANFDGMGHYAKSKLLGQLFIDRLSQHVDPSDVVINLVDPGLTKGTGLMDKSSGLMKIVMAMGTRVVGRTQEHAASAYVDAAIVKGEELHGSYIMDWKICPFGSYYYTEEGKSVQDRIWMEVMDEFAFGRIEEIIGSLMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDR2</accession>
    <name>X0CDR2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDR2"/>
    <dbReference type="eggNOG" id="ENOG502RJ9K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_477372_0_0_1"/>
    <dbReference type="OrthoDB" id="5062424at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="571" mass="65928" checksum="32117E695E4A385E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE42</accession>
    <name>X0CE42_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Galactonate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_07589</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE42"/>
    <dbReference type="eggNOG" id="ENOG502QRWW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2579025at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008869">
        <property type="term" value="F:galactonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034194">
        <property type="term" value="P:D-galactonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03325">
        <property type="entry name" value="D-galactonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023592">
        <property type="entry name" value="Galactonate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010624">
        <property type="entry name" value="PRK14017.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080:SF2">
        <property type="entry name" value="D-GALACTONATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="D-GALACTONATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00003">
        <property type="entry name" value="D-galactonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00179">
        <property type="entry name" value="mandelate_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00908">
        <property type="entry name" value="MR_MLE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="5">
        <location>
            <begin position="126"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK89493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="383" mass="42525" checksum="B64473AB1BC814D1" modified="2014-05-14" version="1">MAKIASVKYYRVKPRWLMVKVVDENGQHGWGEATLEGHDLAVEGCLDEMIPRIIGQEANDIENIWQTFWRHGFYRGGPVFMSAISGIDIALWDLKGRNLKVPVYELLGGKVRNKVQVYCWIGGDRPSDIEAAAKKRLEQGLTCVKMNATEDLGWIDSPSALDSTVERLKQVKALGLDAGLDFHGRCHKAMAKQLARALEPHRPLFIEEPILVEHPEAIKKLSDQTVIPIAFGERLYTRWDIKRFLEDSSVDILQPDIAHAGGISETKRIATMAEAYDVAIAPHCPLGPVAFAASVQVALSSPNFAILEMSLGMHYNTEAGDIDLLTYLKDPSVFDLEGGHVKAPTGYGLGIEIDEEMVARIAKETAPWQCKTFHGPDGSIREW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEZ7</accession>
    <name>X0CEZ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl hydrolase family 13 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07514</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEZ7"/>
    <dbReference type="eggNOG" id="KOG0471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_2_3_1"/>
    <dbReference type="OrthoDB" id="1740265at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033934">
        <property type="term" value="F:glucan 1,4-alpha-maltotriohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004574">
        <property type="term" value="F:oligo-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000025">
        <property type="term" value="P:maltose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11333">
        <property type="entry name" value="AmyAc_SI_OligoGlu_DGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.400.10:FF:000004">
        <property type="entry name" value="Oligo-1,6-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000087">
        <property type="entry name" value="Oligo-1,6-glucosidase IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF232">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 13 CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="3">
        <location>
            <begin position="19"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK89409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="576" mass="66481" checksum="C00EBD1457C51899" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF06</accession>
    <name>X0CF06_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07524</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF06"/>
    <dbReference type="eggNOG" id="ENOG502S3DF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_9_0_1"/>
    <dbReference type="OrthoDB" id="19653at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF3">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BD-FAE-like" evidence="3">
        <location>
            <begin position="22"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="2">
        <location>
            <begin position="231"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK89419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="34529" checksum="A04001BDB47E2485" modified="2014-05-14" version="1">MSPPTLFRAVYKQLGEQEIDVDVYLPSVETDSTKCPVLINIHGGAFMLGSSKMVNKDQVSDCLSRGWIVLAPNHRLCPQVNLFEGPMQDCRDLLAWVYDGGLETPLRNAGSILVPDLDHVFAFGTSSGGHLSLCLGFGVPRPVAGIYDMYGPSNFADDFWTTRLEGMKLPSGLKDSFINKVFDEDPVPITGGVSLEGQATGPPDFSDPRQAYALTQLANGTVLDAIFPSKDWSKVDPALNFDSSFPPTFIVHGAADTKVPIHLSRKLFDVLKQNGVNCCMVEVPGEEHTFAAKMEVGSVTWNLQRQGFDFLESLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGF4</accession>
    <name>X0CGF4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_04778</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGF4"/>
    <dbReference type="eggNOG" id="ENOG502SX45">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103429_0_0_1"/>
    <dbReference type="OrthoDB" id="2328572at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="33"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK93510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="207" mass="22701" checksum="9E530445CE165C4F" modified="2014-05-14" version="1">MFGTWKYDPETDEVQSVRNGFDPVTARSSSHQACDRCHEKKLKCSGDKNGCERCRSNGLRCEYTRSGSKSSKKKSSPRKSNDGDSPSSSSSRRGGSSSKRSSKHHGHSSRIVTSGEEAGGVLSQFDFSQLSPEDGFDLNLLSSADQSAGGYATAGPSGDQYNMQAYDTNYQQWDASGYSQGYSNEAWGSEYDQSAYTHDPRYYHSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGQ4</accession>
    <name>X0CGQ4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGQ4"/>
    <dbReference type="HOGENOM" id="CLU_3279510_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="41" mass="4746" checksum="14C2C8641075F578" modified="2014-05-14" version="1">MSRVIAVDLVVWIRGSGMISVAYRKVGRHWGECFSTRFFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHE3</accession>
    <name>X0CHE3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Mitochondrial dicarboxylate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_05034</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHE3"/>
    <dbReference type="eggNOG" id="KOG0759">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_14_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000107">
        <property type="entry name" value="Mitochondrial dicarboxylate carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="29"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="124"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="224"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK93840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35366" checksum="DB0D5F45478501D2" modified="2014-05-14" version="1">MATSQEAMSKTTETAPVRTGKATADAKKTTIRYPFWFGGSASSMAACVTHPLDLVKVRLQMRTGNAPKNMVGTFVHILRHDGPLGLYSGISASLLRQMTYSTVRFGVYEEVKTRLTRRNDGRDPSFMTLVALAAGSGFVGGIAGNFADVLNVRMQHDAALPPAERRNYRHAFDGMVRMAREEGPKSMFRGWLPNSGRAMFMTAGQLASYDVSKSLLLQYTPMEDNLKTHFTSSFIAGLVAATVTSPIDVIKTRVMSSAYDHNILHLIRDIHRTDGLMWMFKGWVPSFLRLGPQTICTFVFLEMHRKAYRKVKGLDTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CI90</accession>
    <name>X0CI90_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CI90"/>
    <dbReference type="eggNOG" id="ENOG502SCCN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074173_1_0_1"/>
    <dbReference type="OrthoDB" id="4991875at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40640">
        <property type="entry name" value="ANCHORED GLYCOPROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40640:SF1">
        <property type="entry name" value="ANCHORED GLYCOPROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738227" evidence="2">
        <location>
            <begin position="18"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK94140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="226" mass="22378" checksum="9FD4C7199DDC4E10" modified="2014-05-14" version="1">MARSLALLAGALATVAAQTTTVEFLLPMFDPQPLDGSVVAVKGGATTLAIHCPDAKATNCGLAGTSTIVGGPSTIEYSYTMHPEVDGFDGGEIKQNMGCVLDPKKDVATCSVHQVAVLSGITDVTSMTDSVSGYKSLLMPITVTAGVNKLNGNDDASATEAAGSEATSADKPKDTGAKATDAADATTASSDAAATPVSSDNAASPMITQNAILAAAAVVGGAAMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJU9</accession>
    <name>X0CJU9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04676</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJU9"/>
    <dbReference type="eggNOG" id="ENOG502STPI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093542_0_0_1"/>
    <dbReference type="OrthoDB" id="5296964at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="173" mass="19956" checksum="17BB61DC3EC1C74C" modified="2014-05-14" version="1">MSLRRLSGRRGSYSDVLQLTIGVCIEPMEGCPSHWILMLTDRDAEYATCYHSLGGPTKRRPWEVVIESGRLKSWDADHWYYVAEISARHARKVKASARRIPGGFCQRWVVSVLWDLELQEVVPPGTTERIAQVVEEDPYADASPVVEEHEGFHDMMFDWVEKHCWSRLGSPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJX3</accession>
    <name>X0CJX3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-3-phosphoglycerate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12818</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJX3"/>
    <dbReference type="eggNOG" id="KOG0068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_3_1"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000203">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase (SerA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF264">
        <property type="entry name" value="HYPOTHETICAL D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="21"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="118"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="35715" checksum="0644AE7F30054A7E" modified="2014-05-14" version="1">MGSIPTTAPMANSATKPELYILSDFHPEAVKYAQKSFDCTLYGDPRTENWHSHATAILIKDYYITEDDLASAPMLRVIGKQGVGLDKIDVEACKRHNVKVCNTPGVNASAVAEMALCLALTVAREVPQMVIRQRIQGEAIRKETVAGMLLSKKIIGVVGMGHIGQAIAHMFVGGLQAEIIAFDPYFHDNESSWNKIPYKRVKTLPELLEAADVVTLHVPLTPSTKNMIAAPQLKQMKKTAILINTARGGIVNEEDLADALEQGEIWGAGFDCHCEEPPTLAKYERLWKCPRFVGTPHIAAATDETQIATINGATDGILQFLRENKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKY3</accession>
    <name>X0CKY3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03796</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKY3"/>
    <dbReference type="eggNOG" id="KOG2710">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004568_0_0_1"/>
    <dbReference type="OrthoDB" id="3196451at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060237">
        <property type="term" value="P:regulation of fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04396">
        <property type="entry name" value="RhoGAP_fSAC7_BAG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051025">
        <property type="entry name" value="RhoGAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15228:SF25">
        <property type="entry name" value="F-BAR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15228">
        <property type="entry name" value="SPERMATHECAL PHYSIOLOGY VARIANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="70"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="288"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="338"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="561"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="590"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="611"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="729"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="763"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="776"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="845"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="869"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="923"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="950"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="966"/>
            <end position="975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK95100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="975" mass="105608" checksum="09FB7BFCE45790E4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CL76</accession>
    <name>X0CL76_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GMP synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CL76"/>
    <dbReference type="eggNOG" id="ENOG502RRXM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036511_0_0_1"/>
    <dbReference type="OrthoDB" id="3357271at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="42740" checksum="53E70A6C5F728218" modified="2014-05-14" version="1">MSKYKDIMKNGWHPEKPGSSLKGQVKGLVGRGKSEDGDRGSHVSVPLSQLKDPSSFAPPPKRTGSGLLPPPPKAESAPRKVITAPSKYQDPRAPAPQEPVYAEPEEEYEEQPQPRGPYRTNTTGLSTDNLPKPPGRRDGADGRSGQPPSYQSAMAGVGGGGRAAPPSLPPRLPPRTNSGSTVASSPAASPAPTGNGLLNQGAVNRLGAAGISVPGFGIGRSSPAAEASPSPTQPPRPSIASPPPAPAASHMSELQNRFSKLGTSSSANAAAPPPPSEGTTWAQKQAALKTASSFQKDPSSVSLSDARAAASTANNFRQRHGEQVAAGAKTANNLNQKYGLLDKAQNSYSRFQGNQTQTQNEDTPSAPGSPGLASVVGKKKPPPPPPKKKPALMGASAAPSNDEPPPIPMATRPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLF0</accession>
    <name>X0CLF0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SPT2 chromatin protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLF0"/>
    <dbReference type="eggNOG" id="ENOG502SCZV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049218_0_0_1"/>
    <dbReference type="OrthoDB" id="5430658at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013256">
        <property type="entry name" value="Chromatin_SPT2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08243">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00784">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK95245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="41905" checksum="AF48CACD7787677F" modified="2014-05-14" version="1">MPIGDLLAQISGGDEGSSVPPKQGLVRSNTLPKRKADDDPRSSISKAPRVTTLSSTVAPRTTQSPTAVSRPNLPSRPADRSIPSQRPSNPSNGSSKPSVLSSKPMNGGNRVSKPVAPSRPSPGPASASSAPPKKGSFAEILARAQKAQQSMGQVGKIQHKKVEGGALKKVKEEPPAKVDPRAAKSMKQRSAPAPSGYSGTAKPGQRPAQRNGAPVSGTGRDPRNGKPLPPSKAERGKIAGSKSSGRAAPPEEETKKVKKAAMATTGYTGTARPRPGGDVGKKKKEAPRGGALLSAPRAPRPSRSKSRFEDDYDEDLDDFIDYDDEEDDGGPRYDYASDGSSDMEAGMDDIDDEERQAERLAKIEDLKEERLEKQLKAEKEARKRQALEAMRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLN2</accession>
    <name>X0CLN2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_12323</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLN2"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_1"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19079">
        <property type="entry name" value="AKR_EcYajO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000004">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF15">
        <property type="entry name" value="ARYL-ALCOHOL DEHYDROGENASE AAD16-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK83462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="339" mass="38333" checksum="EA4CED8AB648FD38" modified="2014-05-14" version="1">MEYVRLGNTGLKISKVILGCMTFGSSSWQGSPWVLDEEDGLKLLKAAYDQGINTWDTADTYSNGESEVIIGKALKKFNIPRQKVVILSKIFNPVMDDGTRPASINDGPLVNQMGLSRKHIFHAVDKCLERLGTDYIDVLQIHRLDRETPPEEIMRALHDVVQSGKVRYIGASSMYTWEFARLQYIAQSKGWTPFISMQPFYNLLYREEEREMLPFCEATGVGVIPWSPIARGLLAKPLSSKKDEANQSIRSQSDKKTEAWFADANLEIVNRVEKVAADKGISMALVATAWVLQKGCYPILGLNSEKRIKESVEALNVKFTKEELEYLESEYRPRNIQGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNN5</accession>
    <name>X0CNN5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DnaJ homologue subfamily C member 28 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNN5"/>
    <dbReference type="eggNOG" id="ENOG502S4BA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019422_1_1_1"/>
    <dbReference type="OrthoDB" id="1922282at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018961">
        <property type="entry name" value="DnaJ_homolog_subfam-C_membr-28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39394:SF1">
        <property type="entry name" value="DNAJ HOMOLOGUE SUBFAMILY C MEMBER 28 CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39394">
        <property type="entry name" value="YALI0E31793P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09350">
        <property type="entry name" value="DJC28_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DnaJ homologue subfamily C member 28 conserved" evidence="2">
        <location>
            <begin position="247"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="500" mass="55717" checksum="B7D0242F8EB1655D" modified="2014-05-14" version="1">MSVPIRRVPFVCRRCLQVSRQPRTLPPAHYTTQAGASKTEDQQQDKTAKKGEQESGENTVEKELGPLARRLEEATEEALFTGGRAGRRAVEDAGFSEELKERLLNKIADANFKSENASAFAEASLSSTAGEGTRHIASAQAWTGEESTADTVLRMLDDAKKPLAPGLRGKFQPPPVDMRLQKQPRRSAGEKVAKARDKVNTYVGMGGQQAKNGMSEDEKEAWRKELRERFEPGARALPNSITGLAALANERIENAIARGQFKNIPRGKGVERDARADNPFIDTTEYIMNKMIQRQDIVPPWIEKQQEVAKELGIFRARLRNDWRRFAARMIASRGGSLQEQIRRAEEYAAAEEVHNPIIRKKTDGQVEEIKAASPVVGRPFRDSAWEQTEAAYHKLSIERLNALTRSYNLMAPDLAKKPYFSLERELKACFAEVAPTVAREIQERATGGTARSLGGGGQAGKQTGLLETLTGGDNVKVHVEAQEKAYGLKEWWRDVWKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNR8</accession>
    <name>X0CNR8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNR8"/>
    <dbReference type="HOGENOM" id="CLU_3399417_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="31" mass="3686" checksum="F977CB2719ACDEC1" modified="2014-05-14" version="1">MDRGSWLGRRHQQLLEYYRELKNPPSLSAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRK6</accession>
    <name>X0CRK6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha</fullName>
            <ecNumber evidence="4">2.5.1.58</ecNumber>
            <ecNumber evidence="3">2.5.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">CAAX farnesyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FTase-alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ras proteins prenyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Type I protein geranyl-geranyltransferase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_02191</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="4"/>
    <dbReference type="EC" id="2.5.1.59" evidence="3"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRK6"/>
    <dbReference type="eggNOG" id="KOG0530">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026582_4_0_1"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005965">
        <property type="term" value="C:protein farnesyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF1">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK96766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="510" mass="58947" checksum="4AD6931974F63349" modified="2014-05-14" version="1">MPPKTKASSKAPNPEPRAAPESPPDTIAQRSQQRFFQTNPIENRRQQVGLSALTPAEKKTYAHVNLIHPAVNRRVPFSNKTEREFWKFVTKEGLPIRRLPRDYVWGKDRSGRDIGTYSPDELEQRTLKHAKLTSLQIQHRQFLKKREKQLEVTTEEIAAEKTRRKAMAALKRDLYGEITGSLAQDPEWDDVIPIPQNEPEGALAQIAYPDDYAEAVSYLRAVMAADECSPRSLRLTEHVISMNPAHYTVWLFRFKIISVLKLSIPDEITWLNEVALSNLKNYQIWNHRQLLMGHYYPLIEEDTATVRQLARSETQFITKMLESDAKNYHVWSYRQYLVSKLYMWTMSELLSTQNHIEEDVRNNSAWSHRFYLVFSDPTASTPGSGPTEADPRVPAETIDREINYSKEKIDLAPQNQSPWNYVFAVLTKGSRPLSSFKEFAEKFVTALGEEAEEVRSSHALDFLAKLYDEEGDKEKAELCLRRLGEKWDPVREGYWKYRVTLLKSGQSAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRS5</accession>
    <name>X0CRS5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRS5"/>
    <dbReference type="eggNOG" id="ENOG502RAG9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_589297_0_0_1"/>
    <dbReference type="OrthoDB" id="5085439at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937362" evidence="2">
        <location>
            <begin position="19"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK94023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="464" mass="49897" checksum="36BDA90272060AFC" modified="2014-05-14" version="1">MVRFTPLATLALVPLAQARFDWLYPRDTIAQCPPCSLESEPKDCSQTVTVTKPSGPYETVTVSDPNGSYHTVTVTEQDGPGKTVTITQNYQNPQTKVVYISQGETVEPAIETITVTRPGKTVTVTETETETSEHIVTKKIDSYPGPKTVTISNGYPAPSAGSPDYNGGVVTKIVGGDGDHKKDPDNVHTVTVVKDGHIQTLTYKDGNSNTVIKTITQDNGHEEVVTVTGNDQYEVTKTITMENGNKVIETITAENTNNYVVTKTIQQGGKYYTVIVKPEPTVSTITKENGDCITTVVEVDQTYTLTAPAKYGTATVTDDDCETYTRTATYTGKPEVEVIVYDPETGDSTCTKEDGKPCNPSYDNGGDGSKGQYEDPTNTKGQDGSGNYNTNAPVYTKIRTYGNGDVYTEVHGAEPTGCESAAVSTSIATVYNTVIVTVDASPSQAPTAERRAANKVRSPLSVRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS61</accession>
    <name>X0CS61_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM32 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS61"/>
    <dbReference type="eggNOG" id="ENOG502QS3W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1917174_0_0_1"/>
    <dbReference type="OrthoDB" id="10253744at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902:SF7">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00040895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK97275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="132" mass="14565" checksum="CED6BAFEC30E1656" modified="2014-05-14" version="1">MAPVLQTEFEDKLEMEGFDVLHGPVQVNLGDKQRIQGEIGEGKTTARVGLISHIGGHKFAGNVIIYLPPDLKMGDEPHPLAGCGIWYGRVDPKNVEGIVKETILRGNVVADMFRGGIDAEHKMLRIYPKFET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSP8</accession>
    <name>X0CSP8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Nicotinate-nucleotide pyrophosphorylase [carboxylating]</fullName>
            <ecNumber evidence="5 12">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_04445</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>nicotinate beta-D-ribonucleotide + CO2 + diphosphate = quinolinate + 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Hexamer formed by 3 homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="5 12"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSP8"/>
    <dbReference type="eggNOG" id="KOG3008">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039622_1_0_1"/>
    <dbReference type="OrthoDB" id="10067394at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034213">
        <property type="term" value="P:quinolinate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000090">
        <property type="entry name" value="Nicotinate-nucleotide pyrophosphorylase [carboxylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.20:FF:000003">
        <property type="entry name" value="Nicotinate-nucleotide pyrophosphorylase [carboxylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="entry name" value="Quinolinate phosphoribosyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179:SF3">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54675">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 12" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Quinolinate phosphoribosyl transferase N-terminal" evidence="14">
        <location>
            <begin position="40"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Quinolinate phosphoribosyl transferase C-terminal" evidence="13">
        <location>
            <begin position="118"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK94338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="294" mass="31617" checksum="684C3DF8A4B5B9C4" modified="2014-05-14" version="1">MAHPQGNLANLLPPSWKTSVTAWLAEDTPSFDYAGFVVGDGPRVATLWGKSSGIIAGRPFFDEVFTQCGCTVEWHAEEGAAVDLSNGKHRVATVKGPVRGILLGERVALNTLARCSGVATKSQRLVSIAREAGYTGVIAGTRKTTPGFRLVEKYGMLVGGADAHRMDLSAMIMLKDNHVWSRGSITDAVKAAKSVGGFSMKVEVEVQSEAEADEAIEAGADLVMLDNFTGDGVKVASRSLKERWQGKRHFLLETSGGLQEDNFEAYLCNDVDILSTSSIHQGVPHIDFSLKIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSV8</accession>
    <name>X0CSV8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSV8"/>
    <dbReference type="HOGENOM" id="CLU_077715_0_0_1"/>
    <dbReference type="OrthoDB" id="5042684at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="300" mass="35344" checksum="AB1E42B8F2F83C66" modified="2014-05-14" version="1">MNRICPPWRQFELLGGRKRMADTNGMDFGNERAKDALRIVLEIVHGKEVVDYENSSPRLLFYILEVHAWLGHPKATYSSGMDPKMVGTQGAQFSPFFNKDAISGCIFDMEKKAKYLYRVKDWLLLALVAEKLRLHDVMQLVLDNLCLFCRADKRELPEEARDCIKDRDWARIQDLRLIDKNLLNKREFYVDKIFKGLRLLSHQVLYFDGGILLNEKIFNTYQDYKVAACSYCRSLSSDEFHRELISAHLWPLCAETYRERVIDLLHVIRDMEERTLVGRNCNQLTHLYDHLRRMCTESER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT66</accession>
    <name>X0CT66_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_04567</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT66"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="8120565at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF14">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="55"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK94518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="545" mass="58901" checksum="954D01157DDC977C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTB1</accession>
    <name>X0CTB1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Leptomycin B resistance protein pmd1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_02612</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_17_2_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001530">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000057">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000913">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="716"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="760"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="837"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="863"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="978"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="15">
        <location>
            <begin position="68"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="393"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="15">
        <location>
            <begin position="720"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="1042"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="646"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK97401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1296" mass="141201" checksum="7D3E2221A585BC4C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTG4</accession>
    <name>X0CTG4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SVP1-like protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_04629</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTG4"/>
    <dbReference type="eggNOG" id="KOG2111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025895_0_0_1"/>
    <dbReference type="OrthoDB" id="1667587at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK94618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="40434" checksum="6AB5727E93088699" modified="2014-05-14" version="1">MNVRPPIEASSTEAVLSVSFNNDASCFSVGLGSGICIFHTKSCLLKASRDFNAGIGLVQMMGTTNYLALVGGGRSPKFAMNKAIIWDDMKGKVALEITALTAIRGVQLGRERIAVVLQNSVRVYSFAKPPDLLHVYETADNLLGLCCLSEKKLAFPGRTAGQIQLIELATGNVSIIPAHSSALKAIALSPDGELLASASETGTLIRVYATSNCARLAELRRGIDPATIFSLAFSPCGTMLACTSDKSTLHIFDVPHPRKPGMSRSQQLGASGSDPGDGTGKWGILSKIPLMPRVFSDVYSFSSAPFEAGDEAAIGGISFSESTVLGTSRPPKGVIGWIGDDSLVVIGAGHDARWEKFIIVDGEDGKRHCVREGWKRYLGNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUE9</accession>
    <name>X0CUE9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02833</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUE9"/>
    <dbReference type="HOGENOM" id="CLU_1627117_0_0_1"/>
    <dbReference type="OrthoDB" id="5071344at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="163" mass="18291" checksum="27CC93F486D4D2CC" modified="2014-05-14" version="1">MPGVFAVACFCNQNMGRSTSGPRRECRLDGSFQPDPYFPICSFLLSLSESVLFCPQCLMVVLPRLSWMESTYRFVWAYWSNQSKLLGGKATTRHFEKDPGSSCDGICISQQFDFFEDNGAATTGQSRHGSSVLLNTLSAMDGQIRRQTVKEKTIFIVREDADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVG5</accession>
    <name>X0CVG5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_09744</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVG5"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_2_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK86477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="499" mass="56395" checksum="EDF44A4D10AA6491" modified="2014-05-14" version="1">MSGLFDNISDFSREALLTVLSLSLCLLYLSIKIIRRLLFSLLRHVPGPSSTKLTGAAVWLSTIQGRRVYKLEELHRKYGPIVRTGPNEVSISNWRHLRTIYLNTKGMIKNPDFYEAATFVGRDNIFQMINVQQHAARRKMSSPPYSLQSVALLDPLIKGNAQRLAQRLRSGTSSPVDAYTLCGLFSLEVICQAGFAKDFSNDINGAAALKLLQAMDGSALTLLFDGALPFVARFDIGTKLPGAIGDSYRKRDYWREKSYEMVDHFLEKSTDDEKYLLTPLATGVDGYLGRKLTHEELVEEAMGYMFAGSGTTSSTLTYLLYELSKPENAAIQERLRTEVLAIPDDDIVVIRNNAYINAIIKETFRAHPTIISTLPRLLTEPMTLGHYTLPSGTVVGMQNWLHHHDASVFPDPERFIPERWLAETPEMKSALTPFSLGKRNCIGQNLAWQELYWAVSEVMRSGLRFRVAQEMKDWEMEMEDRFNIAPRGRRLMLTVSLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVH8</accession>
    <name>X0CVH8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ran-specific GTPase-activating protein 30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVH8"/>
    <dbReference type="eggNOG" id="ENOG502R7I3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014536_1_1_1"/>
    <dbReference type="OrthoDB" id="512915at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008812">
        <property type="entry name" value="Ran_GTP-bd-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31010:SF2">
        <property type="entry name" value="RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31010">
        <property type="entry name" value="RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05508">
        <property type="entry name" value="Ran-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="68185" checksum="CE0F5BC9C45D0C96" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CX13</accession>
    <name>X0CX13_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GMP synthase (Glutamine-hydrolysing)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CX13"/>
    <dbReference type="eggNOG" id="KOG3179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054974_0_2_1"/>
    <dbReference type="OrthoDB" id="92161at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF5">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="1">
        <location>
            <begin position="63"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="246" mass="27583" checksum="90B2756E51F70062" modified="2014-05-14" version="1">MAPLRLAILEADTPQPQTRDRFGGYTGVFTALLQEAAKPQKLEDLVTIKGYDVVNELHSYPSLDEIDAVLITGSRHTAFDNDPWIIKLVEFTKKAIDTNRIRVVGVCFGHQIVGRAEGAKLGRSNKGWEVAVTEVDLTDKGKEIFGLDKMRIHQMHRDIVDEFPKGSIPLGSNQICEVQGFYSPGRYLTVQGHPEFTNEIISEILFNRHTVGIFTDEVYNEAMKRAPLPHDGVAIAKAFLKFYREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYS6</accession>
    <name>X0CYS6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-glucuronosyltransferase 2C1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYS6"/>
    <dbReference type="eggNOG" id="KOG1192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036519_2_0_1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK96019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="61919" checksum="ADEE0413F81FE7F7" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYZ7</accession>
    <name>X0CYZ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_01923</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYZ7"/>
    <dbReference type="eggNOG" id="ENOG502SI3E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006329_9_4_1"/>
    <dbReference type="OrthoDB" id="5121955at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF2">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="28"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="150"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK99386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="871" mass="98661" checksum="5954876B6713EB75" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0D057</accession>
    <name>X0D057_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetratricopeptide repeat protein 36-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TTC36 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D057"/>
    <dbReference type="eggNOG" id="KOG4555">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074601_0_0_1"/>
    <dbReference type="OrthoDB" id="539634at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006570">
        <property type="term" value="P:tyrosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038906">
        <property type="entry name" value="TTC36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405">
        <property type="entry name" value="CDNA SEQUENCE BC021608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29024" checksum="09BDFF3BD33E5D94" modified="2014-05-14" version="1">MASVCLSKHDINILEKIKDPESNPYAGIVLDSSLPRDPNITDATIYERVVERERDIIRSIQSLETQLKSLGSEEGKDIAVKGYQQSLSAVESMIAEHPNYASARNNRVQILRRLYGDAMMLSDTKDNSAPLIESPDQAERKKAVVTALSDIEASIALLTPSSPTMPISPQVARTLSMAHTQRAALYLKTARLMLSRSLDIDGTLEESKWEKLDFEGAASRDLAFGGRYGNPIAKGLAVSVNPTAKLCGQIVREAMKKEYGPSFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0D312</accession>
    <name>X0D312_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Membrane protein C6F6.13c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_02683</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D312"/>
    <dbReference type="eggNOG" id="KOG2385">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007407_1_0_1"/>
    <dbReference type="OrthoDB" id="277931at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF22">
        <property type="entry name" value="DUF726 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK97514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="651" mass="70968" checksum="09FEBFA81A37393B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D395</accession>
    <name>X0D395_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol phosphate-mannose biosynthesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_01028</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D395"/>
    <dbReference type="eggNOG" id="KOG3488">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150144_2_1_1"/>
    <dbReference type="OrthoDB" id="311279at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180047">
        <property type="term" value="P:dolichol phosphate mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009914">
        <property type="entry name" value="DPM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039:SF11">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07297">
        <property type="entry name" value="DPM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL01216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="89" mass="9804" checksum="D0C4984F0D051FB4" modified="2014-05-14" version="1">MLDKIVGLAMLVAASVVFTYYTIWTLLMPFVDDDHPLQNFFPPRVWAIRIPVIIILLGSAVVGSFLGMVMIRSNQKKAAKAKAAAKKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4M4</accession>
    <name>X0D4M4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_07697</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4M4"/>
    <dbReference type="eggNOG" id="ENOG502RZDV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_7_1_1"/>
    <dbReference type="OrthoDB" id="5283415at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="50"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK89607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="395" mass="43812" checksum="B3D27DF46212BA24" modified="2014-05-14" version="1">MTDPKVAKAIADGRVPKGVTAAYLNQSKDAPAIVGIILVTCLTSIIVLGRLASRAFLIRRFGLDDSLTLVSWLCLVVFVGLCIKLIQLGSGRHFDYIQYVLDMPTIEYTEVLDFGAHIVYTVALLFCRMSGLAFYHRLCAVHDRLRLSIKIVLGILIAGFLPQVLLIVFHCTPVTGLWPYEWQPDFDKYTCLQWGLVYSVNSSVSLVCDLLLFGIPIVMLRVLEMPRKRKIQLGCILLPGISVIAISITRLVFVIEGQWNADMSWAYNPMLAIEVSEIGATLIALSVPGVKPLFDKFILRRDISQGESTGKSRYAQQHSSKGGTALRSLHFRPEHDVLTSRDTSAEGIKTYRTKNVSADNTSENSADGILVQVDFRIKEDTQDSKSGSDAGRSWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5C1</accession>
    <name>X0D5C1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5C1"/>
    <dbReference type="HOGENOM" id="CLU_3392325_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3698" checksum="1DC63F30139CCAA7" modified="2014-05-14" version="1">MKLRTAVVKTLQRLRDRATVVDQRGTREPDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7I9</accession>
    <name>X0D7I9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7I9"/>
    <dbReference type="eggNOG" id="KOG2741">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_25_2_1"/>
    <dbReference type="OrthoDB" id="446809at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055080">
        <property type="entry name" value="Gal80p-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051317">
        <property type="entry name" value="Gfo/Idh/MocA_oxidoreduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708">
        <property type="entry name" value="CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708:SF1">
        <property type="entry name" value="GALACTOSE_LACTOSE METABOLISM REGULATORY PROTEIN GAL80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22685">
        <property type="entry name" value="Gal80p_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Gal80p-like C-terminal" evidence="2">
        <location>
            <begin position="141"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="42432" checksum="F0FD5F4F3575B8D7" modified="2014-05-14" version="1">MAPIRTAIIGLSSSAKTSWASNTHLQYLNSPPGRSKYQIVALQNSSLQAAKNAIAHYNLPPETKAYGTPEDLAADKDVELVVVATRVDVHHSSALPSVKAGKDLYVEWPLAQDVKHARELVDASREKGVKTIVGLQGRYAPPIKKLREIVKEGRIGKVVSAELYASGGTNDREILPASLEYFTQRAVGGNIFTIGLGHIFDQFQYIIGDITNFKSTLHNQRPNIRIRDPKTNEITHTTTSNVPDLILATGRLSESSTAQKDAAVLVRFRRGQPFPGSPHLSITITGEKGEIRVQVFTGTTLHGASAYEKPVVIEVHDFGKDVVEQVEWKWEEWQQDIPLLARGVAAVYEAFAEGEEDGLVSFEEALKRHEQLEGLLGQWDEDRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7N9</accession>
    <name>X0D7N9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="9">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_01775</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="9"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7N9"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_3_2_1"/>
    <dbReference type="OrthoDB" id="7786253at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000014">
        <property type="entry name" value="D-lactate dehydrogenase (Cytochrome), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF111">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="12">
        <location>
            <begin position="134"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK99149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="585" mass="63851" checksum="02E19F3CFC506316" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0D975</accession>
    <name>X0D975_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Small ribosomal subunit protein mS35 mitochondrial conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D975"/>
    <dbReference type="eggNOG" id="KOG3933">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051514_0_0_1"/>
    <dbReference type="OrthoDB" id="283424at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019349">
        <property type="entry name" value="Ribosomal_mS35_mit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039848">
        <property type="entry name" value="Ribosomal_mS35_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10213">
        <property type="entry name" value="MRP-S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS35 mitochondrial conserved" evidence="2">
        <location>
            <begin position="195"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="387" mass="44675" checksum="BE6AD298EFC421DF" modified="2014-05-14" version="1">MASVSRAARLCAMACRRVPRIQQIPRPQQLIRPKPHAQRAFTTSTIRWAREEDQRQDDAEEDDFGPIELKKLEAALAEASTPEGLKQLDQLAKENGYNSIDHYLQNELEWHPGWASEDRSVLEDITRDDKGERPNKQSFWFDEEDPETNTEELEEFDEDDITSMAHGKLDEIRDMRQYARLAVWELPLLSKYAKPFVPPSDNQVLRWRYTSYMGEFHPAEKKVVVQFAPDDLKLTPVQTEKLKKLAGPRYNPETEIIKMSSDSFEHQAQNKRYLSNLVDDLIAAAKDPKDTFEDIPLDTRHHKIQPKPQFPKEWRMSPERREQLDAHRQRLAIEDAKIAESGRLIDGTQAIDEYLIKRAAEDQKKAKIAELVPATPGKSAGGSRARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0DA35</accession>
    <name>X0DA35_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">H/ACA ribonucleoprotein complex subunit CBF5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Centromere-binding factor 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">H/ACA ribonucleoprotein complex subunit cbf5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">H/ACA snoRNP protein CBF5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Small nucleolar RNP protein CBF5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_00349</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs and play a central role in ribosomal RNA processing. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. Catalyzes pseudouridylation at position 93 in U2 snRNA. Also catalyzes pseudouridylation of mRNAs; H/ACA-type snoRNAs probably guide pseudouridylation of mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>uridine in 5S rRNA = pseudouridine in 5S rRNA</text>
            <dbReference type="Rhea" id="RHEA:47036"/>
            <dbReference type="Rhea" id="RHEA-COMP:11730"/>
            <dbReference type="Rhea" id="RHEA-COMP:11731"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>uridine in snRNA = pseudouridine in snRNA</text>
            <dbReference type="Rhea" id="RHEA:51124"/>
            <dbReference type="Rhea" id="RHEA-COMP:12891"/>
            <dbReference type="Rhea" id="RHEA-COMP:12892"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DA35"/>
    <dbReference type="eggNOG" id="KOG2529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032087_3_2_1"/>
    <dbReference type="OrthoDB" id="10250002at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000495">
        <property type="term" value="P:box H/ACA sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02572">
        <property type="entry name" value="PseudoU_synth_hDyskerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21148">
        <property type="entry name" value="PUA_Cbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2350.10:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00425">
        <property type="entry name" value="CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003280">
        <property type="entry name" value="PRK04270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dyskerin-like" evidence="14">
        <location>
            <begin position="30"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="13">
        <location>
            <begin position="280"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="414"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="460"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00072225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00077661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXL00010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="487" mass="53656" checksum="E8DEBB04C1AA4CA7" modified="2014-05-14" version="1">MSKDVAVVKKTTTEEDEYTIKPQATTPSLDTSQWPLLLKNYDKLLVRTGHFTPIPNGCSPLKRDLKQYISSGVINLDKPSNPSSHEVVAWVKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVAVIRLHDKLPGGQAQFARALETLTGALFQRPPLISAVKRQLRIRTIHESKLIEFDNDRHLGVFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGAMDESKGLVTLHDVLDAQWQMDNTRDESYLRKVISPLETLLTSYKRLVVKDSAVNAVCYGAKLMLPGLLRYESAIEHHEEVVLMTTKGEAIALGIAQMSTVEMSTCDHGVVAKVKRCIMERDLYPRRWGLGPVALEKKKLKADGKLDKYGRPNDATPAKWSSEYKDFSASDASAAAAAAAPAKASEAEDTPMEEAATPSSPAADDSKDKKRKKHDGETAEEKAERKRRKAEKKAAKAAKKAAKGEAMDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCE3</accession>
    <name>X0DCE3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCE3"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815:SF1">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="177"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="484" mass="53396" checksum="050E0F8C8DC33B70" modified="2014-05-14" version="1">MATTAMIQPNPPKRSDSDVSPRTVNPPRNSASEDAKVDYFPDSNTVDGSNTSVRASDGDDSSARKSSISFAPDPRRSSSCESNQNSAPGQDSTIQRKSSTGSVSFRRMTNPQLPQGNPQQMNNSRIRASSPNHSRFKKHVAFDNVTTGEPTKNNAISFTLNVRHKGYQARRRSRCFMVGVDEHTYSDYALQWLLDELVDDGDEVVCVRVVEKELRLTDKQYRDDADSVMKGIVARNGNNRAINIVLEYAVGKLHTTFQVLIQMYQPAMLIVGTRGRTLGGLQGLVNTRNSFSKYCLQYSPVPVVVVRPTEKRIKKKAKRANDSARQTYVSMLAANAGKHEADSEASSIYELEVHNSPDEEAHQVARALGLPASFDPTIKPLNHSQIPNRRSPDPTATAGPVNETSENQRVVKDDVSVAAESDDDDDDDDDSGEFEVMSGQQALDRQKMDQLHKMEVGEAAAFKMKVDEELDEEDDTPSAPKATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0DHU8</accession>
    <name>X0DHU8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DHU8"/>
    <dbReference type="eggNOG" id="ENOG502TFM7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_193151_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="55" mass="5696" checksum="6213CAA3E7AA1E9A" modified="2014-05-14" version="1">MACGSSKCLYDRNGPGSAATSIAESIIKPSEATGTKTKCIECGDYECCCIPCTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0DKJ0</accession>
    <name>X0DKJ0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DKJ0"/>
    <dbReference type="eggNOG" id="ENOG502SP43">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090736_0_0_1"/>
    <dbReference type="OrthoDB" id="3890746at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42069">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-8 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42069:SF1">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="232" mass="24728" checksum="34F93DCF0593730A" modified="2014-05-14" version="1">MESSTRNMSIGTKTEISASNFEADVESVRTEPSFRIYRLIDSARLGLTVLGLAAALTILGVSADALAVFHATYVPEDWLLQLWPANFDMRPTVALVVGSALVIGANLVSLIAGKLPTARRNAAVKAAITFVPPAIALVAAIIAMSFFYGVNASTTNDSLQSWTCRWKDVTMNVQPHFGTLCKQSRAGVALSVMLVPVEAIILGLAAYQFTLEKRFDLGARGPSRKAGSPALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-11-27" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0DKT5</accession>
    <name>X0DKT5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF788 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_03742</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DKT5"/>
    <dbReference type="eggNOG" id="ENOG502S72U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094308_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK95007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="17706" checksum="7130B647682EA39E" modified="2014-05-14" version="1">MAQKAKKDRAKSNAAALNNLHIGSLIVNALFLLSHFLFRARSIWLYVLLSAPAVICEYILEASGRPKYDPTTRALRTAGEDLSSPGLTEYMFDVIWVTWAAVIFVIIFGNKAWFLWLILPAYGVYLGSGLLGMGKQKMAEFQGAGDGAGAAPQGNRRARRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0DXA5</accession>
    <name>X0DXA5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-methyl-5'-thioadenosine phosphorylase</fullName>
            <ecNumber evidence="4">2.4.2.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">5'-methylthioadenosine phosphorylase</fullName>
            <shortName evidence="4">MTA phosphorylase</shortName>
            <shortName evidence="4">MTAP</shortName>
            <shortName evidence="4">MTAPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_01572</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-methyl-5'-thioadenosine + phosphate = 5-(methylsulfanyl)-alpha-D-ribose 1-phosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (phosphorylase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.28" evidence="4"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DXA5"/>
    <dbReference type="eggNOG" id="KOG3985">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054456_0_1_1"/>
    <dbReference type="OrthoDB" id="431409at2759"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00873"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09010">
        <property type="entry name" value="MTAP_SsMTAPII_like_MTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1580:FF:000008">
        <property type="entry name" value="S-methyl-5'-thioadenosine phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01963">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010044">
        <property type="entry name" value="MTAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018099">
        <property type="entry name" value="Purine_phosphorylase-2_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01694">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679">
        <property type="entry name" value="S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679:SF2">
        <property type="entry name" value="S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01240">
        <property type="entry name" value="PNP_MTAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 4" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="5">
        <location>
            <begin position="14"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="62"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="95"/>
            <end position="96"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="4">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="4">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK98797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="307" mass="33341" checksum="B7F01839A9A2EFC8" modified="2014-05-14" version="1">MGDLPTTFDKPVHIAVIGGTGLGQLEGFEPVAALNPITPWGPPASPIQILSHKGGYVAFLARHGVHHQFAPHEVPNRANIAALRHIGVRSVIAFSAVGSLQEEIKPMDFVVPDQAIDRTKGIRPFTFFEGGVVGHVGFADPFDAGLAKVVKACAAHMEGDGVVLHEKGTVIVMEGPQFSTRAESNMYRSWGGSVINMSTLPEAKLAREAELAYQVIAMATDYDCWHSFEDVNVELVIKYMKANNENAKRLVAGVLDRLGELENSDLVQAKHWAGASQGAVKFMTKPAGRDPEAMKKVEYLFPGFWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0E2V1</accession>
    <name>X0E2V1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_00712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E2V1"/>
    <dbReference type="eggNOG" id="ENOG502SC34">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059403_1_1_1"/>
    <dbReference type="OrthoDB" id="427960at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10175">
        <property type="entry name" value="MPP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="242"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXL00633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="266" mass="28725" checksum="2DB684303721AE04" modified="2014-05-14" version="1">MAPETPRAVSSRLLTMKFMQRAVASENSSPDSETHSSKKRKTGHSPAAGRLDLNIDQAAIKAALDAQETKRQEALEKHVGADTHWVLDNPFAGLKAASQTKAPLNVVYVGYGDMDSSNDSGDNEDVPRNGRTSTNSFKKAANQKPESQKTSDNESESEDEDSDDANTPAHGQKRKPSSDSPSRSRSRSRSRPTAESAKAKEFRDKRKKKEVKLSKPTSISSGGGISSGGGSQFSPAGKAMTCYKCHQTGHKAVDCPKRGQMAHMYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1Y2</accession>
    <name>X0B1Y2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658761">
        <property type="protein sequence ID" value="EXK76125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1Y2"/>
    <dbReference type="HOGENOM" id="CLU_3392404_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3628" checksum="72C4D4BBC783F717" modified="2014-05-14" version="1">MTVPRSRPVAAVNTALYPFIKMEMYGYDIVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0B218</accession>
    <name>X0B218_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_19452</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TM2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979818">
        <property type="protein sequence ID" value="EXK75781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B218"/>
    <dbReference type="eggNOG" id="ENOG502T1IV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150788_0_0_1"/>
    <dbReference type="OrthoDB" id="408511at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007829">
        <property type="entry name" value="TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050932">
        <property type="entry name" value="TM2D1-3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21016">
        <property type="entry name" value="BETA-AMYLOID BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21016:SF25">
        <property type="entry name" value="TM2 DOMAIN-CONTAINING PROTEIN DDB_G0277895-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05154">
        <property type="entry name" value="TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="TM2" evidence="7">
        <location>
            <begin position="90"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK75781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="156" mass="17436" checksum="DEF514BB3D0E10E9" modified="2014-05-14" version="1">MTLSSIMNHFRATRRTSVHSGTAPWIGKGISLVERHWKLLATVYSVIVLGVIVSCGITIAIERPFDLAKRSWGGFDERPTTAKCYRQERTAMLLAFFLGSFGIDQFYAHHWPLAVFKLLTLGAGGIWWFVDIVLWMVGGVYGTPGCPGGSEHSWQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0B286</accession>
    <name>X0B286_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979757">
        <property type="protein sequence ID" value="EXK75861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B286"/>
    <dbReference type="HOGENOM" id="CLU_041953_0_0_1"/>
    <dbReference type="OrthoDB" id="4151048at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15486">
        <property type="entry name" value="ZIP_Sip4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052783">
        <property type="entry name" value="Metabolic/Drug-Res_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK75861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="301" mass="33718" checksum="591B8A182E129B54" modified="2014-05-14" version="1">MHLTSKRADSSAATIQHYRHAPRTVGIDGRDKRVWKACERCRMKKTKCDGEFPCKRCKDDGLVCTAAIRRKMKYKQLPPGYAEVLENTQFAFIATIHKLYSMVVNNQPWELGEPELNNHGQPIIHSIAQQLGCIRPQSDIKLPVHSVFPENEAGLPEAAPQLEGQQDDNGQQMEDKDADCSVYNRTDQGPLSPQTFTYSTNDFGFAPPLPDSDAAAKCPPQSSSMPNFPAWLMTGKSQLSNPTMQFMQQSASLNNVDQWYQSLVGSQCSTISPHVLLCPNPEVMMGMEDPMIYFTYDGEHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3Y8</accession>
    <name>X0B3Y8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658714">
        <property type="protein sequence ID" value="EXK76471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3Y8"/>
    <dbReference type="HOGENOM" id="CLU_2960887_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="59" mass="6531" checksum="18496234C00FA67F" modified="2014-05-14" version="1">MYGRGAGVPGGSILRIGTVDDFKLSETALRPTIEQYIKHRVDWIKDIENMVQIVGQASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6W4</accession>
    <name>X0B6W4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658565">
        <property type="protein sequence ID" value="EXK77875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6W4"/>
    <dbReference type="HOGENOM" id="CLU_1115797_0_0_1"/>
    <dbReference type="OrthoDB" id="4968544at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="249" mass="27544" checksum="439455B70E0BD190" modified="2014-05-14" version="1">MPEEPPQPKVPQTLQEFEGSEEIVNPPCDDKILDIPCQKWPATGKNCLVIFPTKNEDKVQAFKANFENRKPDDINACFFLRIAVPDDGCSQPCNGQGYVRARSRILKAMEIFRTRKDYETYLEDNGIGQIIVATIESFFVTDGVPRPVDAAVVGMFNVLTGKTVTETSKGVTLNKWFLEEAKKSGGLVDGNQDCLCMTAGEIVAREFPGVNKADWHKFAVGISRGQILKETASGMKIPWGGYGTSRDEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7L0</accession>
    <name>X0B7L0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_17171</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658543">
        <property type="protein sequence ID" value="EXK78140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7L0"/>
    <dbReference type="HOGENOM" id="CLU_003059_0_1_1"/>
    <dbReference type="OrthoDB" id="4975800at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="3"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK78140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="434" mass="48605" checksum="B7917E749E13A34E" modified="2014-05-14" version="1">MSVKKAIQDFTDLSQRVFVSQPIWARAFNLIARGSIYGSSAIDEALKRHYGESKLSDYTPATARAAKILVTVKGTPKGDHILSNFNGVGLDNSHKDFEQTFCHPDDEEGQKAILAWEAARSTSAAPVIFPTFTIDGVGTFQDGAMWRNNPADVALSLVPALTQGHCLPDILLSIGTGFEKRLQRGHREPQPPTRVTIPLVDLLRRLYAFMGDNIVTDGEKFHNHIMAGRSDVGSRFRRLNVPLSEGCPLLDDASSIPRLMDEAAAHFASHPSMQEVLDSIISSFFYFEVSSRPIRHRTHVSFCGRILCDVQPGHRLNHFIKDLRIRGAEFSINGRFTALDSIGEWNGREVDFEIPVRGTVAGLHTRLEIFLCWNMLGRQSKEMISRSPFSLNEIMEAQGWDSPQSRALRQPVRSGRKRGIDCRAAWKRITKARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0B841</accession>
    <name>X0B841_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_17026</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979364">
        <property type="protein sequence ID" value="EXK78295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B841"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="33832" checksum="290698FFEDC62D54" modified="2014-05-14" version="1">MGSAGSKSVRFNPDTDIPSLKDKVILVTGGNSGLGKESVLQFAKHDPKEIWLGARSEARAKEAINDIKAQVPNAPIKFVKIDLASFKSIRDAAKVFTQESDRLDILLLNGGIMSVPPGTTDDGYEVQFGTNHMGHALLTKLLLPTLLRTADKGADVRVTVLASSAHQYAPPEGIKFDTLKSQALQMGTITRYGQSKLANALFAKELARRYPQLTTASLQPGLVTTNLANTMSDNSWIMRLAWKLTTLFIGVDVPTGTLNQLWASTSKDVVSGTYYEPIGRTGLGKPHTNDRALAAKLWDWTEKELEGEKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9M3</accession>
    <name>X0B9M3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16511</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658499">
        <property type="protein sequence ID" value="EXK78845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9M3"/>
    <dbReference type="HOGENOM" id="CLU_058862_1_0_1"/>
    <dbReference type="OrthoDB" id="295274at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="188"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="269" mass="30144" checksum="C6E2898B09884AC0" modified="2014-05-14" version="1">MAQSAAPPMDPMCEPSAIDNFGTMSHPAWEQCWAADQPNFPGPSEAAGGDAQHEYDIEDFVLNYGYTPASSNLTESIFSQEYPTPQRTSELTSPEKSPSNSDARRRSSSTQSDKQKRKPNHAERAPAKSSGRDSTKKTKAKAEAAAEVHGHTKKRGSINEAAATNLSSPHFKNNAYTRKVHERNRIASNKFRIRKQEDERKLKSAEKDMEQINRDLSTCATDLTLQVYNLKMKLLQHTDCDCALIQEYIANEAHRYIQDLGDKKQCQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BA12</accession>
    <name>X0BA12_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658489">
        <property type="protein sequence ID" value="EXK78995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BA12"/>
    <dbReference type="HOGENOM" id="CLU_1165871_0_0_1"/>
    <dbReference type="OrthoDB" id="5103904at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="224" mass="25300" checksum="2D367B8560239046" modified="2014-05-14" version="1">MESRALTKSPNFARQQLAYPAIAVGADDRESLSVTDHDMPTHGKPSQDESNIVLEFQSRVMSAFISDPAAWLRRERWHLKMDNSTTQPRGIKLDSNASHRTAPPDSVTESQVSSEDLTIENVDENLVSPATIKSRSEHYQLLDSSQEPERDAVYLALDHAGLSSTLLCQEFGFREDLPLEQLAYTDSQQRFCPNHPGQAQMEDCFKVVNTKWLHRTNGDKRSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBP6</accession>
    <name>X0BBP6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979564">
        <property type="protein sequence ID" value="EXK76233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBP6"/>
    <dbReference type="HOGENOM" id="CLU_059956_0_0_1"/>
    <dbReference type="OrthoDB" id="4161428at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="33526" checksum="1A6F4AA6BC49100A" modified="2014-05-14" version="1">MSSNSMADLVNEYVSVALKYHEKAIAMLRKQLEYSKPDTRTREDVTQIVEMLEKSTIERPLTAEEALRLRPSGSLSKKLVVCSEDDARKIFDKGPPCFPVLVVESRTPQHISIDWFLDILETRANLDVHDFGKNIKNKGRVAERIPSSSAIDMFKSRQKMQRNGSQIYPLNFLNLNGIKDNAVPGFLANRKDFKILELSREENGKREYRTESTDLDESTSFHLLASQGAVHLPHVDHHYVYTTIFNEEGHKLWLMWPGLGIDGLQTWRETGQVPDGGIPVYIAPGLFDDRDNALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBZ3</accession>
    <name>X0BBZ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_16053</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979348">
        <property type="protein sequence ID" value="EXK79306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBZ3"/>
    <dbReference type="eggNOG" id="ENOG502RUUF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019101_1_0_1"/>
    <dbReference type="OrthoDB" id="3903189at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF166">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="22"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="273"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="331"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK79306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="363" mass="41356" checksum="881A1921E711B90F" modified="2014-05-14" version="1">MEDPTLFIHWFFSCLSLLIMGVRLIWRKVAKQKFVLGDYLTMGAILCCAVRLALIHVVLTWGTNNIKPSLREKMVFTDEIIYRREIGSKFAITNRVFYNSFLWLQKLVLLDVYRRLLLNLRYEKTVMYSFLLVFFGTYVAVQVTTFSECVPFHLYWQVVPDPGTCSKAQLQLIVVGVLNIVTDVMLLAVPIPLFFSLKTSWKRKLKLYVLFTLGIFIVAITVIRLPINAMNKDSQVNRTTWASTELLTATIVVNAPTLYGFWNKKKQGTGYVYSHSQSNGTGMRSRKNTRATGTLGDDPTTETFALGTVRHSRQPSEGILRTQEITVTEYIDSRKNSKGTGSRTDETEVASNSSQLSILRDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC17</accession>
    <name>X0BC17_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658731">
        <property type="protein sequence ID" value="EXK76368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC17"/>
    <dbReference type="HOGENOM" id="CLU_090709_0_0_1"/>
    <dbReference type="OrthoDB" id="5090817at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="197" mass="21802" checksum="361A7AD6F3D08F4D" modified="2014-05-14" version="1">MTLDKKTTKRENMPNGDEANDSMDDAMRNATTQRTELPSDMPQLGGTREEENNETTAKLFCTPSSSPSSSPRRFFTPSGSYAREKLVEHQSRRAEARSEIVEKDRKRVEAGMIKQAIAESLKTTTITQACTTVQKTDQPKPLSSLKDPLPHDEKDNSSSSFPREVASPAGSEDSDEGAWLDELPHEELINNGMTSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCU6</accession>
    <name>X0BCU6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylosidase/arabinosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_18955</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979548">
        <property type="protein sequence ID" value="EXK76299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCU6"/>
    <dbReference type="HOGENOM" id="CLU_114415_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052176">
        <property type="entry name" value="Glycosyl_Hydrlase_43_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772:SF2">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK76299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="15666" checksum="8E6E28C3A0D78AF7" modified="2014-05-14" version="1">MISLKAGTWHKITGLEDFREGLFVNYRDGTYHLTYSIDDTRSENYRVGYATADNPIGPWTYCGVILQKDESLDILGTGHNSVINIPGTDEWYIAYHRFHIPDGGGFRRETTIDKLPIDKDTGLFSSVKPTLESVGPRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCX6</accession>
    <name>X0BCX6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_15781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658466">
        <property type="protein sequence ID" value="EXK79646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCX6"/>
    <dbReference type="HOGENOM" id="CLU_023132_2_1_1"/>
    <dbReference type="OrthoDB" id="422206at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049680">
        <property type="entry name" value="FLVCR1-2_SLC49-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 49 MEMBER A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK79646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="469" mass="50571" checksum="56630D8B211E5EE2" modified="2014-05-14" version="1">MKSQDVKVVDGGALAAVDTTTSVHEGIIDQQSIKPKVYKRRFIGMAMLFALNLCSSMAWIDMASVVDFAAKHFSTSTSAINWFSTSFLFVALAANWPASRTTRKSVKLSMIISSAIMIAGTWVMYGGTHIKSFGLSLFGHCIIAVSQPFVLILPALLSEAWFESGSRATATAVSSIANILGSTVGQFIMTAWVKSEEDVTHGILYQSILLTVVGCIVVFVPSKPPTPPELVVAHERTLSQRQELQVLLTRVEFYLVAIPFGMLSGIFNALSFLIFQMCIPYGFTADQCTIAVCLVIVPGLVTSLIVCRAADIYRCHKWVLKTLTVITGAGFLAFIWVPPSGSIAFLYCISIIISIGVVGSGPIAVEFVAEIIYPLGPELAIAIMWAMGQLFGGVLTIGEGYMTDKNGGLQPGIYLQTALALFCVPFTVSLGLWGRHKYVQLNRTRAEEARQNPNNGGADDAILASKATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE95</accession>
    <name>X0BE95_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658683">
        <property type="protein sequence ID" value="EXK76789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE95"/>
    <dbReference type="HOGENOM" id="CLU_1917164_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="128" mass="14201" checksum="5225F102A73F1F4B" modified="2014-05-14" version="1">MVMGSQSSFEEFVSLRAYGCVAARNDMPSCLLYWSDDGQSVGWGQGVEISMGQFRALTEYLIKEVNSLCNSLMFGLEPDIDLSQIKDDMTNNDNGYSFVTDPKEQIDISLPGPPHARLHSPARVSFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGP0</accession>
    <name>X0BGP0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Frequency clock protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979379">
        <property type="protein sequence ID" value="EXK77639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGP0"/>
    <dbReference type="HOGENOM" id="CLU_007103_2_0_1"/>
    <dbReference type="OrthoDB" id="2536795at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018554">
        <property type="entry name" value="FRQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09421">
        <property type="entry name" value="FRQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="523"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="727" mass="80994" checksum="69A04372E576AA77" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI79</accession>
    <name>X0BI79_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13734</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI79"/>
    <dbReference type="HOGENOM" id="CLU_657294_0_0_1"/>
    <dbReference type="OrthoDB" id="4476201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="159"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="3">
        <location>
            <begin position="238"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="418" mass="47188" checksum="9C3B5770E0AE00B0" modified="2014-05-14" version="1">MASINAPPIDFTNFSYTNLPSPSSIRLLSFIKRPRQLSPPSILGEPLLECILETVDINETPDFDLISSTWGNPDSADPGDTDEYGPMHRYPIAINGKLMFLPKNIYEALKMSHKVNDPVEQRNELFLETELMTAVENNHRPKVQRLLEQGAHIHAQDCFGKTAIHHAAQLGHFDIINILLDYGASMKVIDSHGKTPMDYITYTKPKDWENVEEIAYKMQKTPAERELVPIPEVVRVGRPMWIDAICIDQSNSEERSNHGSLIAQIYCRANSVIAWVGVQNDYTKLATEAILSILRADGKDVDETMSDETLSVANAGCSYIPSEEEKSSIIRFLRRSWFEREDLMHEVAFGRAITVYCGMDALPFSSTMEFLRRKAYSGTFLPPDLQVWSLLGSTGSKKRSSLGSRSRRKRMRRDSISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI85</accession>
    <name>X0BI85_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979355">
        <property type="protein sequence ID" value="EXK78573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI85"/>
    <dbReference type="HOGENOM" id="CLU_921473_0_0_1"/>
    <dbReference type="OrthoDB" id="5410365at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="302" mass="33609" checksum="CD28C1A20857DE7F" modified="2014-05-14" version="1">MPWFKKDPNRPAFVLLESSVPFKSKARFLLGSVVADIRNPTDDFEPDGKSETVFRDYTLNALDTDYSAFLKGNDAHNLSTKVGHLAGVSSNNSSEISTNIKSSVVRTKSLMQHYKVFEQLISSEAKSDIITLMKRNDRKAFLVVGLKSVLDASHVQKFNTEESLNVNIKVPVGKGAEAASHGTVHLGDTVDPEINYTNSSGQKVEIESTMTGERIFAVRYRLITLSRNKPNYGDVVRVKFGTGVFGDKKETEVVFDEGDEEEAQGRDPVVISNDTDEISLSQRYFEDDIELLGLENELEVVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJ40</accession>
    <name>X0BJ40_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658494">
        <property type="protein sequence ID" value="EXK78893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJ40"/>
    <dbReference type="HOGENOM" id="CLU_2704871_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="73" mass="7727" checksum="4D81F40699952AFD" modified="2014-05-14" version="1">MASGLAADAVTSHRSNAAYQVSIDSGPPTILETPTPSQSAKRKRNAQTEPIAKPALQEAGRPKQASQIRYPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJ41</accession>
    <name>X0BJ41_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979359">
        <property type="protein sequence ID" value="EXK78489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJ41"/>
    <dbReference type="HOGENOM" id="CLU_963278_0_0_1"/>
    <dbReference type="OrthoDB" id="5101995at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="272" mass="27753" checksum="7FE282332B1C38CF" modified="2014-05-14" version="1">MGVAASPCKPLTSASVVSSATLTSSVAEPTVSTSVESAVTETSTSAESLVTDALTSTTALTTTSADSTTIFTTETSAATTDFSSTETSADTTTADTTTTTSDAPAEITTFSIIAGSGPAADNNLRSDNNFGSPLYFGSRVTLPAQHYNIDAATGQIKAGTKSICAWFHNSDTTKAYITACTSDNENPNKGVVFLNCQVPTEGSVLQCSVPVLSCIQQGGGEQTCAATTDTLSHFSMEGDDRMVYIVGDGFTGINQTPVDLVIDQAAVAAPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK48</accession>
    <name>X0BK48_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK48"/>
    <dbReference type="HOGENOM" id="CLU_2223337_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="91" mass="10036" checksum="99D04F33EDB288D0" modified="2014-05-14" version="1">MIPLTLSSAIGVTAAKYIVSMPYCYEPREYSQTTGGHDDWAMVTFPGALYDFIFVPISVGQASGPFRHSRKPRLISSDTKINFLFTNEGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK49</accession>
    <name>X0BK49_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK49"/>
    <dbReference type="HOGENOM" id="CLU_2171188_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938627" evidence="1">
        <location>
            <begin position="20"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="133" mass="14791" checksum="64FCF821DA7A7427" modified="2014-05-14" version="1">MKAFSFYILLGALFSRTDAAEQKHIDEACSDVWGVINCDSSITYPNYPRPVNDINGIQIDTEIVPKEVNICDAVRDALGSDDFVNNTETYCTCLSNAVYWGSSSNAKPSFDSQINAHITGPYLDWIHKDETLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLF7</accession>
    <name>X0BLF7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658463">
        <property type="protein sequence ID" value="EXK79713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLF7"/>
    <dbReference type="HOGENOM" id="CLU_037339_0_0_1"/>
    <dbReference type="OrthoDB" id="5062519at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="520" mass="59004" checksum="8F6C7757126B7826" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLL6</accession>
    <name>X0BLL6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658460">
        <property type="protein sequence ID" value="EXK79783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLL6"/>
    <dbReference type="HOGENOM" id="CLU_071337_0_0_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="256" mass="29857" checksum="43334BD2885B5E1F" modified="2014-05-14" version="1">MADNCQYCPTRYRGGRKNPDNVYYSRKWGYTVYRTYYNKESDEAWEMLLYSLEHQTKLALGGFGEEGVDEDDVHVDPDNIQRLKNFLTIEGREDPSQFEGLDAQGIRDFWNAEELKLEQNVVQIPGQRHRLTSRPDEILAMADWVHRFVLLADEATLKDIANGEFIVKAVSLQLPAGNSWPGAWMRIPTGYLLDLWFVLCDWSSSTEKALRFRGSEEELHSWIWPGDDNRSGTGEYSEIRGFPHYNNQTYLEKTWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLN3</accession>
    <name>X0BLN3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Choline transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_15995</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979347">
        <property type="protein sequence ID" value="EXK79389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLN3"/>
    <dbReference type="eggNOG" id="KOG1289">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004495_2_1_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF27">
        <property type="entry name" value="CHOLINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK79389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="56296" checksum="DBB74C8AC3568500" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNI9</accession>
    <name>X0BNI9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNI9"/>
    <dbReference type="HOGENOM" id="CLU_1165873_0_0_1"/>
    <dbReference type="OrthoDB" id="5069028at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="238" mass="27027" checksum="3B36952920D201B8" modified="2014-05-14" version="1">MSDPSLLCIQHSVRNNDSPVHSQAQEKDTLSKFMPIKEHELAQAGGPASNPVSVGDKSEYRTGKHSLKSFMTWNLIGDIDHAECHKEKINQPPSIREDRNGPECDSEFCEQDETTDSPTTSTSHSAARDGVYTSLFEFNRIPSAHRLSLRAHRTQGKVQRVSLLTGRTRRPLHKIQKRLSKESKPLQKDNTIMELMPLAASRNRFLDTDGDIILPSIKEFCEMNESDKEEWQRARSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQG7</accession>
    <name>X0BQG7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sphingoid long-chain base transporter RSB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_14827</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658438">
        <property type="protein sequence ID" value="EXK80694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQG7"/>
    <dbReference type="eggNOG" id="ENOG502QU4U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033465_6_1_1"/>
    <dbReference type="OrthoDB" id="4521223at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF9">
        <property type="entry name" value="SPHINGOID LONG-CHAIN BASE TRANSPORTER RSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK80694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="34138" checksum="26B28A5D045794CF" modified="2014-05-14" version="1">MATFDRNLCTLATCSVEKFGWYHYVPNLGANAFYLAVFAIFAIIQLYLAIRYRVWGTFALGLVLGCVTEAIGYAGRVMQARGDGIFKKKYFVIQLVCLTIAPALISAPIYLSLGRVVKAYGRQFSLMSPRTYAVIFICSDVVSLILQAMGGGLAATGKTQKKVDTGVHILVAGLAYQVLSLAVFIGLATHLWSRVRRMGTKEANPRFTELRASRQLKSFIWALSIATITITIRCIYRVVELSGGFKSEAANDEPSLMVLDGPMIMAALLALTVCHPGPLFFGDWKRLGQDSGYPEIGEEIKQVKQDVERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRR4</accession>
    <name>X0BRR4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRR4"/>
    <dbReference type="eggNOG" id="ENOG502RQ2V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035126_0_0_1"/>
    <dbReference type="OrthoDB" id="10253919at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="527" mass="58907" checksum="B93B3DB86BA6F705" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSS2</accession>
    <name>X0BSS2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658426">
        <property type="protein sequence ID" value="EXK81539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSS2"/>
    <dbReference type="HOGENOM" id="CLU_008809_0_1_1"/>
    <dbReference type="OrthoDB" id="5340195at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF3">
        <property type="entry name" value="FORMYLMETHIONINE DEFORMYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="588"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="672" mass="74666" checksum="E86FF7B34545BEDF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BT52</accession>
    <name>X0BT52_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Inner kinetochore subunit AME1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11011</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BT52"/>
    <dbReference type="eggNOG" id="ENOG502SGUR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019416_0_0_1"/>
    <dbReference type="OrthoDB" id="5377952at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048743">
        <property type="entry name" value="AME1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20994">
        <property type="entry name" value="CENPU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inner kinetochore subunit AME1" evidence="3">
        <location>
            <begin position="436"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="516"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="272"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="638" mass="71509" checksum="C0633D5EF7CA6837" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BU64</accession>
    <name>X0BU64_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-alkyl-2-acetylglycerophosphocholine esterase</fullName>
            <ecNumber evidence="1">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_10530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.47" evidence="1"/>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BU64"/>
    <dbReference type="eggNOG" id="KOG3847">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026278_0_0_1"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF14">
        <property type="entry name" value="PAF ACETYLHYDROLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936693" description="1-alkyl-2-acetylglycerophosphocholine esterase" evidence="5">
        <location>
            <begin position="17"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK85441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="360" mass="38973" checksum="B4FCD6DDD6EF6090" modified="2014-05-14" version="1">MQFSLLFLSLVGAGNAILLPKPSGPYGTALRIEGMTDKSRIDPYDPKKGHRQVLASIFWPIDSSSCSNKVVPYMPPATAKAYGQQVAQLGLSNDTFSALEFQVCKTPVSQKGCASEKKSFPVAVFSPGAGNSRLIYSLMARSLASYGNIVVLIDHPYDPPVVEFPDGKIIKGGNIPDDAKSNQQLGSVKANDISFTISELQRPSFQKKVFKGLPGSIDNKKIVALGHSLGGASAAIAMLSDDRIRGGMDMDGQIFEPALSKGLGKPFFLIGRPNHSEEDTTWKKFYAKLRGPKKEISVKDTVHGSFTDYPQLLKALDLPEAVMKAAAQLVGTAEPSYLQKFLSKTVVDYMKISFAYKGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUK8</accession>
    <name>X0BUK8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beta-fructofuranosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_13053</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUK8"/>
    <dbReference type="SMR" id="X0BUK8"/>
    <dbReference type="eggNOG" id="KOG0228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001528_3_3_1"/>
    <dbReference type="OrthoDB" id="202537at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18622">
        <property type="entry name" value="GH32_Inu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.115.10.20:FF:000002">
        <property type="entry name" value="Invertase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018053">
        <property type="entry name" value="Glyco_hydro_32_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800:SF2">
        <property type="entry name" value="INVERTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00609">
        <property type="entry name" value="GLYCOSYL_HYDROL_F32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936003" evidence="5">
        <location>
            <begin position="19"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="6">
        <location>
            <begin position="45"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="7">
        <location>
            <begin position="437"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK82628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="546" mass="60171" checksum="8D865B0A9A9D223C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVM9</accession>
    <name>X0BVM9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_13137</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVM9"/>
    <dbReference type="HOGENOM" id="CLU_005767_1_0_1"/>
    <dbReference type="OrthoDB" id="3266505at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF89">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="63"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK82569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="746" mass="82626" checksum="E60940BD9C794D43" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXT3</accession>
    <name>X0BXT3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_12344</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXT3"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_2_1"/>
    <dbReference type="OrthoDB" id="256333at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08254">
        <property type="entry name" value="hydroxyacyl_CoA_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="8"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK83324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="330" mass="34297" checksum="7093E46D151B4B98" modified="2014-05-14" version="1">MKAFSYENPTDSLQLKDLPVPEPDDDSVLIEVKAAGICHSDCHIVSGHGDDYIAKKPIVLGHEVAGMIKNLGRNVSGFQIGDAVTLALLMHPVSERVSGAYVGLSFDGGYGQYVVAPQKILVKIPEGISFAQAAVATDALATSYHAVVGEGSARPGLTLGVVGLGGLGMHGLQFACLKGSTVYGFDVNEAKFDQAKSYGAKDCFMALEDATNADIAFDVIVDFVGHSTTTSTAIKAVKPGGKVVTVGLASSDVTIPSNTGSGYILKGVTIVGSIGASMQDLKDVLTLLAEGAIKPELTEVAFEQIPETIKRLAKGTVTGRVWTDPSKAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BY59</accession>
    <name>X0BY59_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12311</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BY59"/>
    <dbReference type="HOGENOM" id="CLU_003059_2_1_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK83449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="855" mass="95092" checksum="AFA05D8D31ADF4E5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYW2</accession>
    <name>X0BYW2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Stc1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYW2"/>
    <dbReference type="eggNOG" id="ENOG502RJS5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_717826_0_0_1"/>
    <dbReference type="OrthoDB" id="3514033at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024630">
        <property type="entry name" value="Stc1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12898">
        <property type="entry name" value="Stc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stc1" evidence="2">
        <location>
            <begin position="23"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="420" mass="46388" checksum="D1DBDF2525233021" modified="2014-05-14" version="1">MPSNNNKGGYKPKAYEAAPTQFRCASGNEWKPLDMFSKAQQRNTRFLIDSGRKFDPGNTGMICKEHNSTPALEHGCVGCDRTLPYDAFSLNQRRLEDWRCLQCVAWDTVAEPSVVPIPKATGHVSVEEEEMMSQGYLAPVEVAQFFDEDDLPGAPITSPESLGLDPNNEDDNKVFNEVVRGSSKTIHSSTTRNFASTTSSVAGDNMSTTSSRATLPPHLQRLLPERLASLSIDEDSVSSSSKVVLPQVSQMASDFPPHLRGLKIAQRTATSSTTGSVSTATTLHKDQEEAAAARKITFNAWDPMGQRHTASKNPTVMSSSASEVSTTEESDQGAKIADGWDDIPPMKEASTRREDKWGNGKEADLRRQQQANFYTNNKWRKINDRYFTQPNIMDQAEDSPGRQRSGHSMQSRNMFDALSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ38</accession>
    <name>X0BZ38_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ38"/>
    <dbReference type="eggNOG" id="ENOG502QQUZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009044_0_0_1"/>
    <dbReference type="OrthoDB" id="66409at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052809">
        <property type="entry name" value="Actin_polarity_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012860">
        <property type="entry name" value="Afi1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245:SF1">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07792">
        <property type="entry name" value="Afi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08616">
        <property type="entry name" value="SPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="2">
        <location>
            <begin position="131"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="845" mass="95109" checksum="4F98D3FC915C6C5D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZE4</accession>
    <name>X0BZE4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_11842</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZE4"/>
    <dbReference type="HOGENOM" id="CLU_006926_3_1_1"/>
    <dbReference type="OrthoDB" id="3990906at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF6">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="77"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK83889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="719" mass="79423" checksum="E5E31596BD4A5E6A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZG7</accession>
    <name>X0BZG7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">N-alkane-inducible cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_08916</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZG7"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_27_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002974">
        <property type="entry name" value="Cyt_P450_E_CYP52_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF18">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE APDE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01239">
        <property type="entry name" value="EP450IICYP52"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK87575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="59194" checksum="91E428B9A5F93548" modified="2014-05-14" version="1">MSSRLSAISLAAFYGLVILYFLNRLWDHISYSIKTKKYKCGPLKTYPHWDPIWGIDFVLSMSRAFKEHRWLSWMEETWAAQGTKTFKARFLGMRMVYSSEMENMKAMSTSQWEEFVLEPIRVDNGVATPFTGKGVSTADGEFWHYSRGIIKPYFERQAFANVARLKPFTDKMLDLIPTNGDTFDMQVLTRRWFLDTSTEFLFGKSRDCLTYPEREDVMLAMVDIMRGARVRLTMSKFMFLHRDPKWYESIRFVHNFMNEYIDQAYDELHQRKEQGEKFADKPERTDLLWDMVQKIPSEDRILLRDQITAVWVPSNETTSIHISNAIYQLARHPDAWEKLQKEVLDLGDEELTFSKLRGMKYMNWVINETHRTIPNGIQMIRVAAHDTTLPRGGGPDGKQPIFCAKGDIVHCNRYLMHRDPDYWGEDAAEFRPERWDGLRPLWHFVPFGGGPRICPAHILVATETAYVLTRFCQKFKGIEARDERGYVPVMRVGPSSLNGIKIAVTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZZ2</accession>
    <name>X0BZZ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979600">
        <property type="protein sequence ID" value="EXK76112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZZ2"/>
    <dbReference type="HOGENOM" id="CLU_2399785_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10360" checksum="7704F16B1CD38B38" modified="2014-05-14" version="1">MYLRWADESHLTMDSRSIPADSSSRSVEIRAILITFSILSTITVALRIYVRYKVLRSLGWDDRVMAAAQLLAIGSAVAIGLGRLQLDIAFSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0J3</accession>
    <name>X0C0J3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0J3"/>
    <dbReference type="HOGENOM" id="CLU_413898_0_0_1"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF82">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="176"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="703" mass="79744" checksum="E85EA30CF67168D5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1V6</accession>
    <name>X0C1V6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1V6"/>
    <dbReference type="HOGENOM" id="CLU_2049825_0_0_1"/>
    <dbReference type="OrthoDB" id="5071337at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="120" mass="13228" checksum="AC95CCAD82CBA8C2" modified="2014-05-14" version="1">MSSEWKPDYRKEDDGAPVYDQKEEQPGPAYEDNSAEVVFEGGSDSGSGWNTDEANESLSVMCAVLTEISAMRESDETEHAKHIIRNNPVPKKQLSNMIVKSITVTVPVIIVESKKSVIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2Q8</accession>
    <name>X0C2Q8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4484 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2Q8"/>
    <dbReference type="eggNOG" id="KOG4704">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019791_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028115">
        <property type="entry name" value="DUF4484"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018626">
        <property type="entry name" value="LCHN/Anr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053056">
        <property type="entry name" value="Lipid_Metab_Assoc_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153:SF1">
        <property type="entry name" value="DUF4484 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09804">
        <property type="entry name" value="DENND11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14831">
        <property type="entry name" value="DUF4484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4484" evidence="2">
        <location>
            <begin position="424"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="618" mass="68117" checksum="7BD91C1CD7D73B2C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3D0</accession>
    <name>X0C3D0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979400">
        <property type="protein sequence ID" value="EXK77277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3D0"/>
    <dbReference type="HOGENOM" id="CLU_2722302_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="87" mass="9983" checksum="3C5D9F57A4AA7F77" modified="2014-05-14" version="1">MLADAAGDRKFPIRFLLNRGSILIYVKEYCSNMFTKRLDGVLLQFVELIQVNDTSTYGDILNEVDRVECIRESKSILFGLKCPVLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3R8</accession>
    <name>X0C3R8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_10532</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3R8"/>
    <dbReference type="eggNOG" id="KOG1282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008523_12_3_1"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010897129" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK85444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="515" mass="57202" checksum="07E57F67E5837406" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4Y9</accession>
    <name>X0C4Y9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Beta-galactosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_07579</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3 8"/>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4Y9"/>
    <dbReference type="eggNOG" id="KOG0496">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005732_2_0_1"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.20.10:FF:000001">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000065">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000040">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="entry name" value="Beta-galactosidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.390.10">
        <property type="entry name" value="Beta-galactosidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019801">
        <property type="entry name" value="Glyco_hydro_35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="Beta-galactosidase LacA, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01182">
        <property type="entry name" value="GLYCOSYL_HYDROL_F35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937373" description="Beta-galactosidase" evidence="10">
        <location>
            <begin position="18"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase" evidence="11">
        <location>
            <begin position="389"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK89480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1002" mass="110028" checksum="4C564D187CE3D765" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C548</accession>
    <name>X0C548_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">hydroxymethylglutaryl-CoA reductase (NADPH)</fullName>
            <ecNumber evidence="2">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_17429</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="2"/>
    <dbReference type="EMBL" id="JH658564">
        <property type="protein sequence ID" value="EXK77882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_236151_0_0_1"/>
    <dbReference type="OrthoDB" id="5077295at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="587"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1483"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1702"/>
            <end position="1742"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="296"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="373"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="629"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="733"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="792"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1223"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1426"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK77882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="2168" mass="243480" checksum="C832F282EDF8AE52" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C595</accession>
    <name>X0C595_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C595"/>
    <dbReference type="HOGENOM" id="CLU_2979119_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="58" mass="6568" checksum="BD5B863DF781EB1F" modified="2014-05-14" version="1">MSEKSTTLKVLGSYLYQQVIITIITWSQSISRSLKTLTAPSFRQVTYRATCLSTVTHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6P2</accession>
    <name>X0C6P2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cystathionine beta-lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_16917</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658522">
        <property type="protein sequence ID" value="EXK78402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6P2"/>
    <dbReference type="HOGENOM" id="CLU_018986_3_0_1"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000072">
        <property type="entry name" value="Putative cystathionine beta-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000066">
        <property type="entry name" value="Putative cystathionine beta-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF35">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE (AFU_ORTHOLOGUE AFUA_7G01590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK78402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="46613" checksum="93EBEE952F56CAE2" modified="2014-05-14" version="1">MDPVQEDSKSRNFVLTAQALHAALPKMAMATRAIHADDFASPHRAIAPPMQVAVNYRYHRDPEQLVPMENKDHNAPFDSHIYSRYTAPNSTRFETVLHNLFGGAGCVTYASGLASFHAIMVLLTPKRIFLGEGYHGIHRSITLQHRVTGVEQLTLDDLGQLGHGDLLHIETPQNPTGEARNLEYYVAIARKAGAYVSVDATFAPPPLQDPLQFGVDIVMHSGTKYIGGHSDMLCGVLVVSKHRQEWMETLYQDRRVMGSVMGSFEGWLGIRSLRTLHLRVIKQSQTAEKLVTWLHEELKSPESLVGKMVDRVQHASLQEADLNDGWLSRQMPGGFGPVFSIWMKREEHAQRLPSRLFIFQHATSLGGVESLMEWRAMSDKGRDPRLMRVSCGVEDVEDMKQDILQAFESLSHDFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6U6</accession>
    <name>X0C6U6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SulP family sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_07347</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6U6"/>
    <dbReference type="eggNOG" id="KOG0236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_8_1_1"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000024">
        <property type="entry name" value="Sulfate permease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="573"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="606"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK89856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="820" mass="89254" checksum="E0326CCD9ABDE04C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6Y4</accession>
    <name>X0C6Y4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09322</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6Y4"/>
    <dbReference type="HOGENOM" id="CLU_064787_2_0_1"/>
    <dbReference type="OrthoDB" id="2687876at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="31462" checksum="1CACFF6AF3785C8F" modified="2014-05-14" version="1">MTNLQKNSNVRLLACLLDGDDIMQSDYRFLVDGSLVKYVITAPGTFLCDHEDRAFEPILLGNLFPQFPPGDWNNGHVARDPATGEPSFVKTEIVQFPGAQNCWHPLRFNELDFTRQERLRQRVHVSMHPDVNAGKPVLVKFAVWPWEVAYVEAETTAYEWLQNSEVVPTFLGHVTEGKDGRVIGFVTEFIEDTRPAESRDIEECEKALKKLHELRIKMDDTNKFNFLVRDGHDVMIADLETAKQACSQDELDEEMKGLRASLEDTSFLGGEYVVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8A2</accession>
    <name>X0C8A2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06846</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8A2"/>
    <dbReference type="eggNOG" id="KOG0137">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10251155at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052904">
        <property type="entry name" value="Acyl-CoA_dehydrogenase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42707:SF2">
        <property type="entry name" value="ACD11 DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42707">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="6">
        <location>
            <begin position="192"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="5">
        <location>
            <begin position="433"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK90640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="638" mass="70183" checksum="1A98541E00563413" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9K3</accession>
    <name>X0C9K3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9K3"/>
    <dbReference type="HOGENOM" id="CLU_1835277_0_0_1"/>
    <dbReference type="OrthoDB" id="4990560at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="140" mass="16229" checksum="6B98C40FE52C13DF" modified="2014-05-14" version="1">MGKLWRSHSGRTGQRRTSGPVDHLPIQAKPEKGSMFTGNEPTSPTKYETTSSDEQLQLVKEMGMIFSYLNHKGIWPKYCAVYEAIYDHMGDFDTWYSTQQGAGTTIPSLLKEWREYNRLVLDSMAHRARDTETWMYNNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9V1</accession>
    <name>X0C9V1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658470">
        <property type="protein sequence ID" value="EXK79472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9V1"/>
    <dbReference type="HOGENOM" id="CLU_3260615_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="42" mass="4815" checksum="CF6C69F3317174E7" modified="2014-05-14" version="1">MAEFMKNAVPTSGNLTNLDKVVYAPMVEVNILRDRFNIELIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CA41</accession>
    <name>X0CA41_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979346">
        <property type="protein sequence ID" value="EXK79562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CA41"/>
    <dbReference type="HOGENOM" id="CLU_059765_0_0_1"/>
    <dbReference type="OrthoDB" id="5102964at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="262" mass="30416" checksum="34AA0BC4AFE0D4D4" modified="2014-05-14" version="1">MRNIDDIVVILQAPRRGHFVGAFMMMFAKMDDVYFHIYSSSVFRKQQGWHSDAKITIQFTTEGVQSGQSTREAKNFWECRAAETLEDPLRKHMTDQAQMPYFYEYFLVFWARLPSVPTIVYDKLVRSHGHRGYQLPIHNSISGYMRKQFKETLPNFQKNIATYAAKMLVEDVGLVDLEWSDNLAAPDELAWEHINHHTKSIRARYQFLLDNSVGPIGDCMNMLRLHCFKTMFSSRSNYFNRHEWVAGRDSGGLARASSEIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAB5</accession>
    <name>X0CAB5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAB5"/>
    <dbReference type="HOGENOM" id="CLU_031398_0_0_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="21"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="2">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="449" mass="51719" checksum="2624DB07E41DBAC1" modified="2014-05-14" version="1">MRLINTHTLQLEFYPGGSRRYAILSHVWGDDEVTFQDVASGDPEEALHLERYSKLRESCRMARSLKLDYLWIDTCCIDKSSSAELSEAINSMFRWYAESTICIAFLEDVPFSESEEEQRKTFATSRWFTRGWTLQELIAPGKVIFYGRGWQRLGSRSELKEDIKSVTGIDYELLDATHHMAEIRQSQLGEFSVAQKMFWAAGRETTRPEDIAYCLLGIFDINMPLLYGEGQVKAFKRLQEEILKSTDDESIFAWRQPRYRVEGKTYWSLLANSPSAFDLGQTSKDLNGLVPKRSKYLSLRSGSSMSMTNRGLDLELPLTPFPIDTSGTIFLAFLNCEFRRGQTSINPAILLQRAAWDRNSHFVRIRPDILALSMMNSIILPDELLNMIRSGQKDVLQEAIPRQIFVPHNTPDLRYLKGVIFRPEMKGLAKESRMVVRHLVLHLDHYKHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB67</accession>
    <name>X0CB67_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_15540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658454">
        <property type="protein sequence ID" value="EXK79922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB67"/>
    <dbReference type="eggNOG" id="ENOG502RXWW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068979_5_1_1"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF15">
        <property type="entry name" value="BLR5631 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="23"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK79922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="193" mass="20356" checksum="803C6C65990343E1" modified="2014-05-14" version="1">MASATSFRDLVGIPASTASPSDSVLIIIDAQNEYAEGQLKVTNAAESRKVIAGLLEKYRAANGSIVHVVHDTPEGAPVFTPGTKLAEEFDELKPKDGEAVIHKNFPGSFTKTDLQSVLDKTGKKKVVLTGYMAHVCVSTTARQADELGFDVIIPEDAVGDRDIPGVDASQLVKVSLSEIGDAFGTIIKSSSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCA8</accession>
    <name>X0CCA8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRELI/MSF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658448">
        <property type="protein sequence ID" value="EXK80292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCA8"/>
    <dbReference type="eggNOG" id="KOG3336">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067902_1_1_1"/>
    <dbReference type="OrthoDB" id="407630at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006797">
        <property type="entry name" value="PRELI/MSF1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037365">
        <property type="entry name" value="Slowmo/Ups"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11158">
        <property type="entry name" value="MSF1/PX19 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04707">
        <property type="entry name" value="PRELI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50904">
        <property type="entry name" value="PRELI_MSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRELI/MSF1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="184" mass="21093" checksum="BB7256A52EECE0B0" modified="2014-05-14" version="1">MKVFSNKVTYNYSWDEVSTANWTKYGPWNNKSEHVIAVDTLSREVDPATGILRTERLITCKQTVPDWIKTIIGGTGDESFMYEASYVDPINKTVTMVSQNLTWSNLVNVQEEVVYKPLGDHQTQFIQNANITALCGGWQRIKNSIEDTMVSRFRENAVKGREGFERVLMMSRKAFAEEKARQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEK0</accession>
    <name>X0CEK0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEK0"/>
    <dbReference type="HOGENOM" id="CLU_2960852_0_0_1"/>
    <dbReference type="OrthoDB" id="4973636at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="59" mass="6782" checksum="1E5ADF04F3A391D7" modified="2014-05-14" version="1">MPGIIIFHASKDDLERIFDEKLQPIKDKLDAINKMLDRLTNHGLAPKTPPIETDIRSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF73</accession>
    <name>X0CF73_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_05278</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CENP-W/WIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF73"/>
    <dbReference type="eggNOG" id="ENOG502SEGJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159428_1_1_1"/>
    <dbReference type="OrthoDB" id="2543597at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13732">
        <property type="entry name" value="HFD_CENP-W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000075">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052484">
        <property type="entry name" value="CENP-W/WIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="8">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK93060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="78" mass="8741" checksum="7EB4E4B1DF715202" modified="2014-05-14" version="1">MALGKKPYPKATVKKIIKAHSNHNLKKNADVTIFLDYVLFMETLIKEAAIHSKQSGERGLSARSVKKVTRDTLTKFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFA6</accession>
    <name>X0CFA6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_07609</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFA6"/>
    <dbReference type="eggNOG" id="ENOG502S43K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_4_4_1"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="141"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK89514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="610" mass="66719" checksum="954DA6ED761B82A0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CG91</accession>
    <name>X0CG91_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_13935</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658424">
        <property type="protein sequence ID" value="EXK81642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CG91"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF77">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="18"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="512" mass="56440" checksum="53418CF88E95221B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHH6</accession>
    <name>X0CHH6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Chitin binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_07101</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHH6"/>
    <dbReference type="HOGENOM" id="CLU_021264_11_3_1"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939418" description="Chitin binding protein" evidence="9">
        <location>
            <begin position="19"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="49"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="11">
        <location>
            <begin position="127"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="364"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="423"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="442"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK90274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="471" mass="50879" checksum="2C070942DD18DA00" modified="2014-05-14" version="1">MKSLTLLSLAALLSIVFAHGFMVRRKGAEFNIAARHEHASAQSEGLEKRASCGKDIGSCPKGQCCSAAGYCGTTSPYCSSPQCQMDYSNGNCDGSKKPKGGTTANIPRSTTGKVPYNVYITNCTTPGTFALTFDDGPYKYTDQVLDVLKQNNIKATFFITGTNLGKGQIDDETTGWPRILRRMYSEGHQLASHTWSHQDLTASSDEVRQQQVIYNEMAFRNIFGFFPKYLRPPYGTCNRVSGCLDYATNLGYHVINWNLDPKDFENNTPDKIQTSKNTFSNGVSTNAKANAYIELSHDVQEQTAYNLTAFMIKTIKDRGYRAVPVGECLGDVRENWYVTDPNFQPSMPVYSATPSPSPTAATKDGTCGAKDGGTKCTGSKWGDCCSYNSFCGSTSGYCDGGCQTDFGKCNKWTTGSALIVSANGLCGDKYHQTCKGSTYGDCCSKGGNCGKTSAYCGTGCQSGFGTCTSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHH8</accession>
    <name>X0CHH8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Replicase polyprotein 1a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHH8"/>
    <dbReference type="eggNOG" id="ENOG502S7CI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045844_0_0_1"/>
    <dbReference type="OrthoDB" id="5320532at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008402">
        <property type="entry name" value="APC_su15/mnd2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05841">
        <property type="entry name" value="Apc15p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="39447" checksum="43EF23B2E04F5E77" modified="2014-05-14" version="1">MFTTLPDFTPRDSHSLWYRSSRSPYTPPGPLDDFSGDTHNIQHGANQARQRTKLIERSALARLAADEQCMQRRRLNVQNYGSGWLKPPGVPKTLHQMREEKREQEEHQEAMRREQLAQELAEAEAEGMPGEGTMDDVQLDGAQDLDDEIPDADEEGYAFGDDDDEEDEEEDEEDGEETDDEALRAERQNDLMQARMRMGDDAFREALVRGEPDANDMYGDTEGLEEEEDNGHLLDEEDFAQDDDLGMDMDADLDEDIPEAESGGYEHTDSEAEISSSEQESSNDDEDDDEDDVDVSFAPRSATLPRPMSPTFQGRSSMAHPRASMDLSNLLSQDGSSFMQSSPAGRRARHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHS7</accession>
    <name>X0CHS7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Membrane anchor Opy2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_06960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHS7"/>
    <dbReference type="eggNOG" id="ENOG502RY3X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030352_1_0_1"/>
    <dbReference type="OrthoDB" id="2402916at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018571">
        <property type="entry name" value="Membrane_anchor_Opy2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09463">
        <property type="entry name" value="Opy2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane anchor Opy2 N-terminal" evidence="3">
        <location>
            <begin position="29"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK90818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="430" mass="45532" checksum="E819761063D9F5F6" modified="2014-05-14" version="1">MMERSGYLVARNLDELNHAFQLVPRSKDCVKCDDGAQLECPKCADNEVCQFTVPLDCTMCATSFCEKDSDNSNNSGGGGPNVGAIVGGVLGGIVVIAIATYIVWRFCIKPKRSQIPTSIYIEDTDAIQNEKDAASRGTRPHSTHTVHSIASTVLTRASNIIQIAYIPGVTNRATPTSPNVLVPPVPPIPMHHAEANRGLGHDDQHFFVPGDLRDSTYSGLSGYSDRTSYARTSYAPRSSVASTIYGKQAQVLTPAQTGMRAKPTVVSVKSVGNNSGDMVAPPVPTIDFEKFGGGRPKSGASAFSVGSTFLNSANTATQARAQVVKVGTLKKVDVGSKTESDTSSSTMAPSPPTTPSGRITRDSSITVIEESPSVDQGPFSDPPERSSPQKSNKAPSLGAVMEDSVGEDDKPLTLTRRDSSPFGDKHATKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKJ3</accession>
    <name>X0CKJ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06740</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKJ3"/>
    <dbReference type="eggNOG" id="KOG1696">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083919_0_0_1"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.240:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1650.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="6">
        <location>
            <begin position="17"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="164"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="164"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK91344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="202" mass="23598" checksum="14D7D6DE15EFD46D" modified="2014-05-14" version="1">MNWLQCFLMVSPRIRVNLRTQKRLASAVIGCGKRKIWLDPNEQSEISNANSRQTIRKLISDGLIIRKPVTQHSRSRARELNLARREGRHRGYGKRKGTADARMPSQVLWMRRLRVLRRLLVKYRASGKIDKHLYHELYHSSKGNAFKHKRALVEHIHRAKAEKARETALQEEMDAKRAKNKAARERKQERAAAKRNALLAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMW2</accession>
    <name>X0CMW2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cysteine sulfinate desulfinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphosulfolactate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMW2"/>
    <dbReference type="HOGENOM" id="CLU_062679_1_0_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003830">
        <property type="entry name" value="ComA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036112">
        <property type="entry name" value="ComA_synth_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48413">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48413:SF1">
        <property type="entry name" value="PROTEIN HEAT-STRESS-ASSOCIATED 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02679">
        <property type="entry name" value="ComA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102110">
        <property type="entry name" value="(2r)-phospho-3-sulfolactate synthase ComA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="317" mass="35660" checksum="F1B84A751C87327D" modified="2014-05-14" version="1">MSHVNLLKAARPVWRASTAIPKAAIRPFSVSRQLRTPPILLEDKDKGFGFIRHNKRPPKPRSVGVTEIRGPYYSVMGKRYLQDVLETMGHHVDGLKFAGGSFSLFPEDKLKELINLAHEYNVYVSTGGWMEHVLLQSDPAWAVDQYLKKCKQLGFDVIEISSGFLSIPQDDWLRIVDKVHSAGLIAKPECGIQFGAGGDTEASELSSLGTSDPSKIIHMGKRFIDAGVERIMIESEGITENVKSWRTDVIQQILRELPQEKVMFEAADPKVFNWYVREFGTDVNLFVDHSQIVQLSCLREGIWGQSDTFGSVVNYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNW5</accession>
    <name>X0CNW5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c oxidase subunit 6B-like protein new16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05241</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase subunit 6B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNW5"/>
    <dbReference type="eggNOG" id="ENOG502S7HF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142408_0_0_1"/>
    <dbReference type="OrthoDB" id="5545577at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.140">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048281">
        <property type="entry name" value="COA6_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048280">
        <property type="entry name" value="COX6B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036549">
        <property type="entry name" value="CX6/COA6-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47677">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47677:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02297">
        <property type="entry name" value="COX6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47694">
        <property type="entry name" value="Cytochrome c oxidase subunit h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK93003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="14945" checksum="EF226B14B7426606" modified="2014-05-14" version="1">MGFWPFSSESRADAIRSGDAIPNRQERKICWAARDAYFNCLDAHNIVDATKDPSATKKACPVETADFERDCAAAWVKYFKQWRVADIQKKRRLDELRAQGAQEMTVTTSFAPEGGAGEKGKGVGDIQAMLDQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNX3</accession>
    <name>X0CNX3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11689</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNX3"/>
    <dbReference type="eggNOG" id="ENOG502SFBR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4226666at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF5">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="360"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="797" mass="88769" checksum="E9B8FEAFE1498593" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP59</accession>
    <name>X0CP59_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP59"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937320" evidence="2">
        <location>
            <begin position="22"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="332" mass="35771" checksum="EE5B8BF9E22C1CCF" modified="2014-05-14" version="1">MAGDGIAFFIFRLFILNQILGRVPRPTASFEGKTVIITGANTGLGFEAARHIIKLGAARLIIAVRSTEKGEAAKSVLAESTGCDPAILEVWPVDLASYASVKAFAARAIAELPRIDALIENAGIASEKWSWAEDNESMVTVNVVSTFLLALLLLPKLRETAARYNTRPNLTVVSSDMHYTVDFNEKDAPEGIFNSLNNEKGADMVSRYPITKLLEVFIVREMAARRPVELCPVTINTTNPGLCSSGLGGGEEGLLFKVGSFLFARSAEVGSRNLVYSASAGAETHGQYLDRCKIQEPATIVTGPGGKTTQERVWDELIAKLEKVQPGITGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ86</accession>
    <name>X0CQ86_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Amine oxidase</fullName>
            <ecNumber evidence="11">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_02058</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="11">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="10">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10 11">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="11"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ86"/>
    <dbReference type="eggNOG" id="KOG1186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011500_3_1_1"/>
    <dbReference type="OrthoDB" id="5379943at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.20:FF:000001">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF91">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="13">
        <location>
            <begin position="5"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="12">
        <location>
            <begin position="248"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="9">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="10">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK96615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="672" mass="75048" checksum="FA060ABBF288C259" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQB9</accession>
    <name>X0CQB9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11195</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQB9"/>
    <dbReference type="HOGENOM" id="CLU_000288_138_8_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="3">
        <location>
            <begin position="22"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="4">
        <location>
            <begin position="223"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="693"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="727"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="760"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="793"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="826"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="569"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="888" mass="99418" checksum="A397394658FF1AB5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQK0</accession>
    <name>X0CQK0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TAFII28-like protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02124</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF11 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQK0"/>
    <dbReference type="eggNOG" id="KOG3219">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035243_2_1_1"/>
    <dbReference type="OrthoDB" id="28335at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08048">
        <property type="entry name" value="HFD_TAF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045127">
        <property type="entry name" value="TAF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006809">
        <property type="entry name" value="TAFII28_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04719">
        <property type="entry name" value="TAFII28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII28-like protein" evidence="7">
        <location>
            <begin position="169"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK96690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="320" mass="34829" checksum="C115666948023C57" modified="2014-05-14" version="1">MASPPYATSPSGMSPPYPSPAQIPNKKRPSTLDGSAPPLKRRKPSQTSVSTSSAAHPLRQTSFPPEARSPFPRSPSVDAQSHVSGSAVSTTASGAPKKKRGRKAKNAKPDDAREQTPSLVGGRAPTAVSGQGGEKEDDDEDDEKAEMALEDVVARTQEQKQEEIRLRAMLVEAFDSQQYNRYELWRAAKLADSVVKRVVNATVSQSVPQNVSTAVKAVAKLFAGEIIEAARNVQGEWIHAGEKQSELPTPPPSTNDDPAAAEEEIDLKRGPLRPDHLREAWRRYRLSGESRGVGVQQLWHAQQGDGVERFSTRTGKRLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSG6</accession>
    <name>X0CSG6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Auxiliary Activity family 9 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSG6"/>
    <dbReference type="HOGENOM" id="CLU_032571_1_0_1"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF2">
        <property type="entry name" value="LYTIC POLYSACCHARIDE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939574" description="Auxiliary Activity family 9 catalytic domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="3">
        <location>
            <begin position="31"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK97091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="406" mass="40698" checksum="A0650F45430D7BE6" modified="2014-05-14" version="1">MFAKAFTFASLASLASAHMLMNNPKPYGSPDNSPLDASGANFPCKGAVNDGFVNNVYKQGSTQQLSFTGQAVHGGGSCQVSLTTDKNPTKDSVWKVIKSIEGGCPSRTATGNLGDNAKAENPDKYDFTIPEELAAGEYTLAWTWFNHVGNREMYMNCAAINVEGSGGSKDYLDSLPDMFVANIGNDCETLADTDLKFPNPGKDVSKLKTLLTDAKGEGCQKAGSGGGSGGGSGGDDSQPSAPVAAPTTNVGAQPTQPATTPAPSAGNGSGSGSGSGSNGTPEVPGGAFITVSQPSAPQPTATQAPAAPETPTDGSGSGSGSGSGSGSGGSDSGAGSSGFAAGTACTNEGEWNCIGGSTFQRCASGAWTAAQQLSSGVTCTPGQSADIAMITKRGKRNMRRAKRSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTC0</accession>
    <name>X0CTC0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor TFIID subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02615</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAF13 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTC0"/>
    <dbReference type="eggNOG" id="KOG3901">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076665_1_2_1"/>
    <dbReference type="OrthoDB" id="10266074at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07978">
        <property type="entry name" value="HFD_TAF13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003195">
        <property type="entry name" value="TFIID_TAF13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380:SF5">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02269">
        <property type="entry name" value="TFIID-18kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="109"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK97411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="163" mass="18387" checksum="DC29807E582E3CEA" modified="2014-05-14" version="1">MEPRARAGKNVGKMNFSHAELAQLLYAHGDVQNPLPETVRVLDEILTDFMQSIAFEATRAANYSGRQKIKYEDFEFAFRKNPAFLGKVQEVFEKQKEIKKAREILRDGEDEIMKDAADEEKKREKSDTRTGGAVGAATSRVEEELGEADDDAEAEFDALGKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTT1</accession>
    <name>X0CTT1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Light induced alcohol dehydrogenase Bli-4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02893</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTT1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF236">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK97855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="35209" checksum="846BAC89545C6EF8" modified="2014-05-14" version="1">MTVRTQLFPPSPTFTESSLPSLNFRVYIITGATSGVGLELAKILYSRSAIVYIAARNYSKITSAIKEVQSAFPDSTGRLESLCVDLSDLASIKPAAQQFLAKEIRLDGLVLNAGVMMPPEGSKTEHGHELQMGTNCLGGYLLSRLLEELLVKTTVVADEGTVRVVWLASTPQMGTPKGGLVWDEVKKEPKVVKDQMENYMMSKAGNLLLAHETSQRLASQGIISVAVNPGFLKTELQRHMPGPVSFMMGLMFKAPKYGAYSELFGLLSPDITADNNGVLIYPWGRIGCIPDDIKVSLKNGQEGGTGLSKAFADWCEREARQYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVV1</accession>
    <name>X0CVV1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_09483</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVV1"/>
    <dbReference type="eggNOG" id="ENOG502SJNH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5430750at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF3">
        <property type="entry name" value="ZINC TRANSPORT PROTEIN ZNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="644"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="674"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="328"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="588"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK86607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="773" mass="87273" checksum="4DFF216DAD33CDAA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWP7</accession>
    <name>X0CWP7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pt repeat family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWP7"/>
    <dbReference type="eggNOG" id="ENOG502QQV3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_269727_0_0_1"/>
    <dbReference type="OrthoDB" id="5144858at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="628"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1070"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1112"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1172"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="538"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="754"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="853"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="883"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="935"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="970"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1081"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1172"/>
            <end position="1184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1249" mass="138347" checksum="FBE87FB0F16BA0E4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYG7</accession>
    <name>X0CYG7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar sorting protein Vps3844 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03406</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYG7"/>
    <dbReference type="eggNOG" id="ENOG502S64Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054960_0_0_1"/>
    <dbReference type="OrthoDB" id="5583277at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053065">
        <property type="entry name" value="Archenteron_Induction-Rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024382">
        <property type="entry name" value="Vps3844_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853:SF1">
        <property type="entry name" value="DUF3844 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12955">
        <property type="entry name" value="Vps3844_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938061" description="Vacuolar sorting protein Vps3844 C-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar sorting protein Vps3844 C-terminal" evidence="4">
        <location>
            <begin position="264"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK96328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="368" mass="40033" checksum="7EE43C914DBB4B5D" modified="2014-05-14" version="1">MKLNIGLSAAFAGIAAASQQPAADGTKVYILRGSHHIEPTTSITPSEARLILYQRLAPEGQDFSFRDLTASDDEVRVVSLMNKYGKVPAPLLSDEKTATPRQLAITIDGMPSFEYESFFGWLFNTQPDFTTDISKENGEHPEVFANVLAKMPECPLSQIAALDEKCFNGQSAYASYSRSQDGDHPTTLLNELPKLQKLAESGELQTILVFLPVDVDSEDKSDKDQELRRRQAETVISSIEETAESPAETSTTPAKPSNPIKAVCFTSEDSCMEATGNCTGHGKCLNKYGQSKDSCFACHCQVTKSESGSVTHWGGNMCQKQDISVQFWLFAGFTIALLTILYMAIGMLFSVGEEKLPGVIGAGVSRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYS7</accession>
    <name>X0CYS7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phenylacetyl-CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08955</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYS7"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_2_1"/>
    <dbReference type="OrthoDB" id="1898221at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="49"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="458"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK87617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="61409" checksum="EF10686D7E0F5469" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ62</accession>
    <name>X0CZ62_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ62"/>
    <dbReference type="HOGENOM" id="CLU_536456_0_0_1"/>
    <dbReference type="OrthoDB" id="3513892at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="26"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="529" mass="61905" checksum="0E0387711F993165" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZE9</accession>
    <name>X0CZE9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4419 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02097</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZE9"/>
    <dbReference type="eggNOG" id="ENOG502RPX4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037155_2_0_1"/>
    <dbReference type="OrthoDB" id="9978173at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025533">
        <property type="entry name" value="DUF4419"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31252">
        <property type="entry name" value="DUF4419 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31252:SF11">
        <property type="entry name" value="DUF4419 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14388">
        <property type="entry name" value="DUF4419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="43793" checksum="0F361287B425D6F9" modified="2014-05-14" version="1">MPVTVAIPNREVSSWQGPKAEKTSQLLRGASSQEANGCNQIIQSSFSFNGSLEENHVSASRNGLVWSSFHAYSTHHHLTIRPEDVWFAIVTQISAYINANSEKMRDYFVSHDGQKKLEVIDYATLHTADFGKLSQLMALEIANNIKDPALREWVLPSFSTTTENDRIVGSVLLMGALQKYFSYGMTMLCGIPSVTLLGEVTDYEDILKRLDKLEEMGEEPIQFANLLRPILRNMVLSFTQPSDRAIHTFWNQIADMDRMSGSNKMTGWITAFCYWDDEGKVHPPSRANCTLEGLMYPYVETDNIPCGYVTVPVEVDDNGTLYNCKMLAGSVGIQAIPDPEGYVPTFDPCEKRRRDVEVDEKKLGIKPVTGWMIYEFVERKGPGRRRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0G6</accession>
    <name>X0D0G6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Cytochrome c oxidase assembly protein COX20, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_02387</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the assembly of the cytochrome c oxidase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the COX20 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0G6"/>
    <dbReference type="eggNOG" id="ENOG502S3BD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101495_0_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022533">
        <property type="entry name" value="Cox20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586">
        <property type="entry name" value="CYTOCHROME C OXIDASE PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12597">
        <property type="entry name" value="Cox20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007871">
        <property type="entry name" value="Cox20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK97053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="169" mass="18984" checksum="F7BBC506F9888D27" modified="2014-05-14" version="1">MASNPQDGQSMPGDKTLHVWSKPIEQNEATTVNGEHGATPTNNRPTISEAVSMIKKDDFTNVANTPCARQGFITGIASGAGIGGLRFVLKGNPSSAANWAVGMFVLGSMASYEWCQYLRREERRQMKRHIEVVSENRREQARKIQEARREHDKLEAEKKAVVKPWYKVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2R9</accession>
    <name>X0D2R9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2R9"/>
    <dbReference type="eggNOG" id="ENOG502QWQE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033097_0_0_1"/>
    <dbReference type="OrthoDB" id="5308502at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018830">
        <property type="entry name" value="DUF2434"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10361">
        <property type="entry name" value="DUF2434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="550"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK97863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="581" mass="66787" checksum="AD8F0CC3B9D6102C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3N0</accession>
    <name>X0D3N0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Restriction of telomere capping protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_07915</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in a process influencing telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RTC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3N0"/>
    <dbReference type="eggNOG" id="ENOG502SEU0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030573_0_0_1"/>
    <dbReference type="OrthoDB" id="128308at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039024">
        <property type="entry name" value="RTC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028094">
        <property type="entry name" value="RTC4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391:SF1">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14474">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01312">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Restriction of telomere capping protein 4 C-terminal" evidence="9">
        <location>
            <begin position="438"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK89257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="554" mass="61474" checksum="E6C709127F43E02C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5Z5</accession>
    <name>X0D5Z5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WDR59/RTC1-like RING zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_01434</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0309">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001497_1_0_1"/>
    <dbReference type="OrthoDB" id="311712at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049567">
        <property type="entry name" value="WDR59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049566">
        <property type="entry name" value="WDR59_RTC1-like_RING_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17120">
        <property type="entry name" value="zf-RING_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="212"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="WDR59/RTC1-like RING zinc finger" evidence="5">
        <location>
            <begin position="1307"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="387"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="624"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="733"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="783"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="624"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="735"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="792"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK98564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1451" mass="160354" checksum="E0A0CD69F6DD8676" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0D942</accession>
    <name>X0D942_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dolichyldiphosphatase</fullName>
            <ecNumber evidence="11">3.6.1.43</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_00394</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a di-trans,poly-cis-dolichyl diphosphate + H2O = a di-trans,poly-cis-dolichyl phosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14385"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="EC" id="3.6.1.43"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the dolichyldiphosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.43" evidence="11"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D942"/>
    <dbReference type="HOGENOM" id="CLU_074922_0_0_1"/>
    <dbReference type="OrthoDB" id="302705at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047874">
        <property type="term" value="F:dolichyldiphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03382">
        <property type="entry name" value="PAP2_dolichyldiphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.144.10:FF:000003">
        <property type="entry name" value="Dolichyldiphosphatase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039667">
        <property type="entry name" value="Dolichyldiphosphatase_PAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF1">
        <property type="entry name" value="DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="12">
        <location>
            <begin position="54"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXL00084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="237" mass="26530" checksum="A71D096BE39D0578" modified="2014-05-14" version="1">MDDSSTPLASLSVTHVYYDPNDHISLACAYLALLPQALCVVYATLVLFTREVEVALMFLGQLACEVLNFALKRLIKEERPRRIHGKGYGMPSSHAQFVAFWSVSLALFLLVRHKPPHVHQVRAESGLHRPWSVLERVAVSVAGAAIAAATAWSRVYLNYHTPKQVVVGSVAGVISALGWFLIVATVRQTGWLNWALETPLARAFRVRDLVTEEDMCQAGWEKWEKRRAAARTIKKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0DB14</accession>
    <name>X0DB14_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DB14"/>
    <dbReference type="HOGENOM" id="CLU_3106401_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="51" mass="5918" checksum="AE17FBF3ED1293B4" modified="2014-05-14" version="1">MAEATGPRHPDSSVRGARQRKDQRLLKRFESEILEETLKVYQCQARDDVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0DB39</accession>
    <name>X0DB39_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS transporter, metabolite:H+ symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_06459</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DB39"/>
    <dbReference type="eggNOG" id="KOG0253">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4139357at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000171">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01740)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="487"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="89"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK91787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="544" mass="59432" checksum="B178F582CCA2779E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBB1</accession>
    <name>X0DBB1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Knr4/Smi1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_00605</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KNR4/SMI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBB1"/>
    <dbReference type="eggNOG" id="ENOG502QTAZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024700_0_0_1"/>
    <dbReference type="OrthoDB" id="2305498at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070880">
        <property type="term" value="P:fungal-type cell wall beta-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009203">
        <property type="entry name" value="Knr4/Smi1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051873">
        <property type="entry name" value="KNR4/SMI1_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432:SF1">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017023">
        <property type="entry name" value="KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Knr4/Smi1-like" evidence="3">
        <location>
            <begin position="152"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="469"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXL00420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="519" mass="56906" checksum="6523BC926B47E655" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBC9</accession>
    <name>X0DBC9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SNF2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_00822</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBC9"/>
    <dbReference type="HOGENOM" id="CLU_141739_0_0_1"/>
    <dbReference type="OrthoDB" id="5105430at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXL00854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16500" checksum="9CCDCCDBF1ABB5E1" modified="2014-05-14" version="1">MGLSSSPPRLDICTSKRVLPWRGEVGLILVEASHLIITEPFWAPGREEQVIERTHRLPQKREVHVCRVVSHPSMVDELVNDSRSSQLGQIHKDLYGVLIGKDDEAFDRELLSTRAAPEQEVEVEVKVELLDLEDANDGIMKRINAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCD0</accession>
    <name>X0DCD0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_00782</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the U5 snRNP complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCD0"/>
    <dbReference type="eggNOG" id="KOG0333">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_11_2_1"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17945">
        <property type="entry name" value="DEADc_DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000322">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057479">
        <property type="entry name" value="PRP28/DDX23-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25430">
        <property type="entry name" value="DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="199"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="230"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="444"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="596"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="13">
        <location>
            <begin position="199"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="599"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="620"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXL00770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="634" mass="71201" checksum="10BF2498564E3B6E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0DED2</accession>
    <name>X0DED2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DED2"/>
    <dbReference type="eggNOG" id="ENOG502RJNJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057889_0_0_1"/>
    <dbReference type="OrthoDB" id="3437607at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="307" mass="34350" checksum="13B513663798B8BF" modified="2014-05-14" version="1">MLRLQPTTIKIATRDISDAERRSRYRKHLLSRQKANKRRDDLTQLDQGTVLEDALNTRIVTPTTDSSIGQDTPGSDGRNESDGEEELGSSVPPLDYGTISSEETTYVDVVHGTNRLHRQPDQHRLPFRPRQSLDDHEHADTAPVHTQPHDNVRDGSMTDEDERDTIEQPLAATLDGSTYESEEVNDDLLQTSGELVDPPEDAGELSISPADEGLEPTTPRRHFPVYSDRLPVEEQPQTPRQLPEARHQSRFDGVYTAPVRGRRVRVEIDDAPVTVRRRRAGRNTSPVGLRTPGFQGLYGGSENADDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0DM11</accession>
    <name>X0DM11_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATPase synthesis protein 25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_03981</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial mRNA stabilization factor.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable mitochondrial mRNA stabilization factor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Mitochondrion inner membrane</location>
            <topology evidence="2 8">Peripheral membrane protein</topology>
            <orientation evidence="2 8">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the ATP25 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DM11"/>
    <dbReference type="eggNOG" id="ENOG502RGZN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016140_1_0_1"/>
    <dbReference type="OrthoDB" id="107372at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140053">
        <property type="term" value="P:mitochondrial gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048255">
        <property type="term" value="P:mRNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040152">
        <property type="entry name" value="Atp25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28087">
        <property type="entry name" value="ATPASE SYNTHESIS PROTEIN 25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28087:SF1">
        <property type="entry name" value="ATPASE SYNTHESIS PROTEIN 25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK95407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="644" mass="72294" checksum="D32D575DF69DC45E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0DMF2</accession>
    <name>X0DMF2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_04110</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21992"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:21993"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DMF2"/>
    <dbReference type="eggNOG" id="KOG4534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_511984_0_0_1"/>
    <dbReference type="OrthoDB" id="3361892at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032931">
        <property type="term" value="F:histone H3K56 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016849">
        <property type="entry name" value="Rtt109"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF2">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE RTT109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51728">
        <property type="entry name" value="RTT109_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="307"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="325"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK95547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="518" mass="58492" checksum="A63F53D9463F4133" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0DU67</accession>
    <name>X0DU67_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-14 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02837</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DU67"/>
    <dbReference type="eggNOG" id="KOG4159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF51">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SPX" evidence="7">
        <location>
            <begin position="20"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="430"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="190"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK97777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="58841" checksum="DD7EF2DAECD41D55" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DVW0</accession>
    <name>X0DVW0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DVW0"/>
    <dbReference type="HOGENOM" id="CLU_2386230_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="94" mass="10433" checksum="B8E787A97FA1C280" modified="2014-05-14" version="1">MARPDCQNQYGGPADLAVASCFSSERAKMIALKRAGEDEMAAPCNNVFYRWFNSPQNGCTIEAKRTVVDRYNCDAKRLCDIPNRVSTGARGREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0DWI4</accession>
    <name>X0DWI4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DWI4"/>
    <dbReference type="eggNOG" id="ENOG502QPW5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003596_0_0_1"/>
    <dbReference type="OrthoDB" id="3941926at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="970"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="733"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="750"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="892"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1073"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1111" mass="120066" checksum="7021ADD0D405F833" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0DYE8</accession>
    <name>X0DYE8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Transaldolase</fullName>
            <ecNumber evidence="4 10">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_01784</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transaldolase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="4 10"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DYE8"/>
    <dbReference type="SMR" id="X0DYE8"/>
    <dbReference type="eggNOG" id="KOG2772">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047470_0_1_1"/>
    <dbReference type="OrthoDB" id="2015515at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00957">
        <property type="entry name" value="Transaldolase_TalAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000088">
        <property type="entry name" value="Transaldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004730">
        <property type="entry name" value="Transaldolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00874">
        <property type="entry name" value="talAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF18">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0704">Schiff base</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK99162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="323" mass="35547" checksum="E206299B536A2B1C" modified="2014-05-14" version="1">MSSSLEQLKATGTTVVSDSGDFASIGKYKPQDATTNPSLILAASKKAEYAKLIDVAIDYAKQKGGPIDQQVDDALDRLLVEFGKEILKIIPGKVSTEVDARYSFDTEASVNKALHLIELYGEQGISKDRILIKIAATWEGIKAAEILQRDHGINTNLTLMFSLVQAIGAAEAGAYLISPFVGRILDWFKASTKKEYSKEEDPGVQSVKTIFNYYKKYGYNTIVMGASFRNTGEITELAGCDYLTISPNLLEELLNSNEPVPKKLDASQASSLDIEKKSYINDEALFRFDFNEDQMAVEKLREGISKFAADAVTLKSILKEKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0DYR5</accession>
    <name>X0DYR5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_01846</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DYR5"/>
    <dbReference type="eggNOG" id="KOG0804">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009969_0_0_1"/>
    <dbReference type="OrthoDB" id="273556at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16457">
        <property type="entry name" value="RING-H2_BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12717">
        <property type="entry name" value="RRM_ETP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011422">
        <property type="entry name" value="BRAP2/ETP1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034931">
        <property type="entry name" value="ETP1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047243">
        <property type="entry name" value="RING-H2_BRAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007:SF7">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07576">
        <property type="entry name" value="BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="359"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="8">
        <location>
            <begin position="395"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="38"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="675"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="559"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK99282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="703" mass="78135" checksum="A8B342376FC14724" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3N2</accession>
    <name>X0B3N2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arabinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979457">
        <property type="protein sequence ID" value="EXK76710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3N2"/>
    <dbReference type="eggNOG" id="ENOG502T63H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010779_0_0_1"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08983">
        <property type="entry name" value="GH43_Bt3655-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936682" description="Arabinase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39784" checksum="782A350C0870E9D4" modified="2014-05-14" version="1">MLSILNPSIILSALAVLPILTSASPTRAIRTGAELAKREISCNSNYEGYAFLYFSNRDENIYLAASNGNDALSFTELNNGKPILKSTKGDGGVRDPFILRSHKGDKFYILATDLCIGCGTSWGDAQRFGSRYLEIWESKDLITWSAQRHVEVSPDNYGNTWAPEAYYDDDLKTYVVYWASGIYDNGANPDHDPTAYQRMVYATTDDFITFSKPKVWQDEPPNGRIDSTVIKEDGIYYRFTKATINGCADIVQESSASLTAGLDDWHMIASCIGKNAGTQEVEGPSIFKTNCKDVNGARYILLADEFGGNGYVPLESTDLAGGKWTLRTGYKYPESPRHGTIIPLTLEELEGIQKAFANMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0B408</accession>
    <name>X0B408_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979499">
        <property type="protein sequence ID" value="EXK76491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B408"/>
    <dbReference type="HOGENOM" id="CLU_036632_5_2_1"/>
    <dbReference type="OrthoDB" id="3918601at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38794">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38794:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="2">
        <location>
            <begin position="3"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="189" mass="21320" checksum="3083D0C99E9C7899" modified="2014-05-14" version="1">MFIASVFCCKLSCTVGLRMISRESQRWIVFGFEAVVGGWGASALIVNLFQCQLPTPWIYTNDRKCIDRATFWTYYSIINITTDIGIIILFCENVLKIQIPWSKKILAMSVFGSRILVIPAIAVQIYHSNKAFASTDVTFANWEAAIALQLVQCLSIVTICIPSFRPLLNSLESGQIRIDDLRRRAQCTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4K7</accession>
    <name>X0B4K7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_18605</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979465">
        <property type="protein sequence ID" value="EXK76661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4K7"/>
    <dbReference type="HOGENOM" id="CLU_020030_0_0_1"/>
    <dbReference type="OrthoDB" id="5130013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF8">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK76661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="530" mass="59332" checksum="C5C3DF9CEA31BE57" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9S1</accession>
    <name>X0B9S1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980097">
        <property type="protein sequence ID" value="EXK75573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9S1"/>
    <dbReference type="HOGENOM" id="CLU_2776036_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="69" mass="7666" checksum="C9738FA3323FD214" modified="2014-05-14" version="1">MVFMNTLQQPQFLQKGVNSVNFAFGANTVLKPWPSTFNVNRITLPKSVLVSSKLQAMLIASLESLRLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCT3</accession>
    <name>X0BCT3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_15462</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658453">
        <property type="protein sequence ID" value="EXK79975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCT3"/>
    <dbReference type="ESTHER" id="fusox-w9nll6">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_6_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="2"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK79975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="465" mass="51305" checksum="4DFF6539700D8599" modified="2014-05-14" version="1">MLPVLVWIHGGGLVEGSAIDQRYNLSFVVRQSEAIGMPIIGISLNYRLGALGFLNSDEVAKTGNTNLGFKDQRLALRWVQENIPAFGGDPEQVTIWGESAGAFSVGAHLTAFGGRDDRLFRGAIMDSGNPVFYLPVFPAQYFQPSYEALLKMTGCNNSADGLECLRQVPIAELSKVFHASPSLWSGFTPSKDEDFIQGSGSELLSKGKFVHVPILIGTNTDEGTYFASKDPTPKNISSDAEFISYLQDNQHLPTPFIQEVLRAYPDVPSEGIPGVPTLPASYRPGYPYGSQWRRLAAYCGDSVIIANKRWTSQIWSSAGLCVYSYRFNIVPASIPGVFGASHVQEIPFAFYNHNGIGYNKENMSPWNGTEEPFEDKRADYAEAARLMSSLWVSFVHDQDPNSFGRGGCGIGNRSVPLWPTYTKGGKNGTNFVFSSAFEFYLEPDNFRFNAINLLMSRNEKSHTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEH6</accession>
    <name>X0BEH6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658441">
        <property type="protein sequence ID" value="EXK80565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEH6"/>
    <dbReference type="eggNOG" id="ENOG502SXHQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5358884at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="27944" checksum="9FAA10CA761FA549" modified="2014-05-14" version="1">MSQQQHLPDSEGLQVNTDAEQAAKAPEVAPGYDNGNYYIPPGYHHPQQASSDGVRIPFGLGVWTFAALVALCTAIVVGAGVGGGLGAALANKSSDCSADSASGTAPAATAEPTATSCPTPDNSTSVNDTAPYVPRAADTVSLLELDCPDSKKDETRYKTNKGYEFKWWCGVNAAQGTPAEGGGIVADYAPIYAYTIGDCMEACGNMIDKDAETGNGVKCASIVFSKRMKDELDGLNANCWLKNNSKAQGSNWGFKDDWYAYAELDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEW1</accession>
    <name>X0BEW1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Tryprostatin B 6-hydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_17899</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979391">
        <property type="protein sequence ID" value="EXK77383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEW1"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_10_1"/>
    <dbReference type="OrthoDB" id="6692864at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902181">
        <property type="term" value="P:verruculogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000063">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF187">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK77383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="63349" checksum="82B3193892B11323" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF17</accession>
    <name>X0BF17_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658446">
        <property type="protein sequence ID" value="EXK80406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF17"/>
    <dbReference type="HOGENOM" id="CLU_033726_0_0_1"/>
    <dbReference type="OrthoDB" id="125347at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF1">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="34851" checksum="B8C08DD0FCCB43BE" modified="2014-05-14" version="1">MENAENDQERKARKRAQNRLNQRARRERLRRENEDRNGPGKRPYRVDRWRIGTDANTEEKLKTAPAQDMALSREEKESPSQQLIIANQYNYNSGVVISVDHRLLHLISYNVCRGMMTNKKMMRLFAEFIMAFDFPTLEPQSKTYCDIAVVRPLDREHLPLPTRLEPTQIQMNSPHPCWIDILPFPDLRDNLIRKQLTYDHIQFLEDLVGDFVYILPPAVPSSRCVAPPLKRLEGGYQPKESAGMILWGEPHLSESWEVTPSFMARWSWLIGECKDLVRVSNNWRQSRGEQPLRSVRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFC9</accession>
    <name>X0BFC9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979337">
        <property type="protein sequence ID" value="EXK80521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFC9"/>
    <dbReference type="eggNOG" id="ENOG502SHR0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084275_1_0_1"/>
    <dbReference type="OrthoDB" id="4831122at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936283" evidence="1">
        <location>
            <begin position="18"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="260" mass="28312" checksum="4389FF0699EE2880" modified="2014-05-14" version="1">MIAPKFILLSLAAVASAAPFMTERDLNATLWTPDHILKQDEVILYGEGRMEVVHVSVYEKLLESEGISPITPEIDQDWLDAGSKAVAPRDLEERQSCGSTTSYVTDRTERFVDWDVQMSPVVIGAGRSGIDVSVASSFSISNGVSVSAGLDLKAVKDRLGASFGINYSRTWTTQATVTVRGTVHDGETGVVITRPWTNRRYGRQFRGCVGSMQQTGTWMADAHEEGSYEGVKWVAGAITMCIKRQSGIPLSRCNGGGNFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFD2</accession>
    <name>X0BFD2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979384">
        <property type="protein sequence ID" value="EXK77553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFD2"/>
    <dbReference type="HOGENOM" id="CLU_1245428_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="222" mass="24914" checksum="9506011EE532D01B" modified="2014-05-14" version="1">MEDGSEDGHVALIKELEAAMSKEAARKGQLVTDHPDPEALVEAPRKESTKRNGTAEKASFSVTQIPDLYEPCVIPEEDLEPMPISDMRLKTHHRGKKVLLWVKTAPARVTVVVTIVEDEEGTEVLLALYQQLQENLLTVRHPAQDSVAILKGPFFEQTAEGTYSLQVVHPSDIIWLEDHNERIPEHWRVHRKIKSSAEYRAEGEGLASKEHWLPALHSSVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFG3</accession>
    <name>X0BFG3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979408">
        <property type="protein sequence ID" value="EXK77189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFG3"/>
    <dbReference type="HOGENOM" id="CLU_078562_0_0_1"/>
    <dbReference type="OrthoDB" id="4311043at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF3">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="339" mass="37617" checksum="D1DE062CF08BBA6B" modified="2014-05-14" version="1">MAATIEWFGATTYRLQTNGLTIFLDTWLDKPARMPRYLELADVKEADYIFISHAHFDHLPGADVIAKRTGAIIVANGEAINIMREAGVPEKQLLPVGGGERIPLFTKELHDKAAQSLVELERRPPGAPKSPHPSLAVAAVHVWPSLHAFLPEDHPEIMDTGVRYTGASTDFFCTLNITMGMKHGLLRLKDVIPEDKIDQDTQAFIGYVDDRDKNRFSHYDGGQLMFNILTEGQVLLWSAHLGGYEGVLRDLTPRPDVAIIAAAGRANLNGRPFDGSAAEFLVKKAKWIEEPKKIIWCLHDKSLVKPFSVDTTAATAAIERETQSVIQDLVPGQKYKVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFL6</accession>
    <name>X0BFL6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycosyl transferase 64 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_18038</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979402">
        <property type="protein sequence ID" value="EXK77249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFL6"/>
    <dbReference type="HOGENOM" id="CLU_051555_0_0_1"/>
    <dbReference type="OrthoDB" id="1733656at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015338">
        <property type="entry name" value="GT64_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48261">
        <property type="entry name" value="ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48261:SF2">
        <property type="entry name" value="ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09258">
        <property type="entry name" value="Glyco_transf_64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase 64" evidence="6">
        <location>
            <begin position="88"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK77249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="336" mass="38509" checksum="FFD50BF629C4B493" modified="2014-05-14" version="1">MASYIGALLYRLSRRGAIIFLAVCLSSLFFLSFVSFQAHISRGIQDFAELPGGLQDKHVECSGRQQAATRDIWNAAERKYRDLRDDYFTVAIQTYRRPKELNNTLHLLLGTKIPSLLEIVIIWNDVQIKPPEDFVSPYNVSVRYRVSRRNSLNEKLWPDPNYRTKAILLSDDDVHYNPSDLDFIFQTWRKNGQNRLTGAFARCVSMSSEGQWQYSLCGNMDSYSMILTGLAFTHIAFLDYFSSHDPLMTEIREYIDTTFNCEDIAMNFVASMLTCKGPLQISGAEKPVNVMPKKGISTKPGHMKIRSKCVKDFIEFFGYLPLRNTTEYIARGLIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGM8</accession>
    <name>X0BGM8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658552">
        <property type="protein sequence ID" value="EXK78003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGM8"/>
    <dbReference type="HOGENOM" id="CLU_2399780_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="93" mass="10701" checksum="C3D0477BBB551CEE" modified="2014-05-14" version="1">MYWMSGPSFRTCSLGISQTETASFSINYCRSISVKNGPNEMWRQLRQRGGRIWLTGYCCLKAGVSRAPIRTVVDLRPISGCSKVWRYLYGRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGW3</accession>
    <name>X0BGW3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14494</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979336">
        <property type="protein sequence ID" value="EXK81066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGW3"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_0_1"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF53">
        <property type="entry name" value="ALPHA-GLUCOSIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="60"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK81066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="544" mass="60743" checksum="ECDE6DF267957BFC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHH4</accession>
    <name>X0BHH4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_17029</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979364">
        <property type="protein sequence ID" value="EXK78298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHH4"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF236">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="34846" checksum="D79E49B1328A209F" modified="2014-05-14" version="1">MSLNFGMRCSTVVPNKPPLTEQNLPDQKGKVFLVTGASGGLGKLLVDILYRHNGKVYLAARSQSKTEEVIQEIKSAHPSSTGELHFLHLELDDLSTVKPAANRFLEKEGHLDVLWNNAGVMIPPEGSKTKQGYELQYGVNNIAHFLLTLLLRPALEAAAASAPKNSVRVVWVASSAADAAPNPAVDLTNMDYHREEGAWMKYSRSKAASVIHSAEFARRTKGTGIISLALNPGNFVTNLQQNMSKMELAMFKLISSDPINGAYTELFAGLSDTITEENNGGWVSPFGKVENIRKDFVEPELGSKFWDWTVEQVKPYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHP8</accession>
    <name>X0BHP8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit 5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_16938</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658524">
        <property type="protein sequence ID" value="EXK78388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHP8"/>
    <dbReference type="HOGENOM" id="CLU_085114_0_0_1"/>
    <dbReference type="OrthoDB" id="1262810at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK78388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="225" mass="24205" checksum="438ABBD14D1F0A1B" modified="2014-05-14" version="1">MFSRQASRTVRAATLHPAASLRAGPARNFTGTTNDSRPPVYLYGLDGTYATALYTAAAKMSTLDLTNKAVVNLSNIFIKDTKLTKVLSTPRLTAEDKSAIVAELSKHTGTNVVTVKNLLQTLAENNRLGHLQGVCEKFGELMSAKRGEIEMTVTSAERLDNKTLSRLETAVSKSSYVGQGKTLKVTNKIDPEIIGGLIVAVGDRTIDLSVGARIAKITKVLTDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI59</accession>
    <name>X0BI59_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">nitrilase</fullName>
            <ecNumber evidence="4">3.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_17165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a nitrile + 2 H2O = a carboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21724"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18379"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="EC" id="3.5.5.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.5.1" evidence="4"/>
    <dbReference type="EMBL" id="JH658542">
        <property type="protein sequence ID" value="EXK78154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI59"/>
    <dbReference type="HOGENOM" id="CLU_030130_6_0_1"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000257">
        <property type="term" value="F:nitrilase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07564">
        <property type="entry name" value="nitrilases_CHs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000132">
        <property type="entry name" value="Nitrilase/CN_hydratase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044149">
        <property type="entry name" value="Nitrilases_CHs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044:SF14">
        <property type="entry name" value="ARYLACETONITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044">
        <property type="entry name" value="NITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00921">
        <property type="entry name" value="NITRIL_CHT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="5">
        <location>
            <begin position="6"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00036406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK78154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="326" mass="35354" checksum="55A34FB5BCD3D954" modified="2014-05-14" version="1">MSSRIIKVAVTQAEPVWYDLPATVKKTLHLIAEAASNGARLIAFPECWLPGHPLWIWSNPGDPDLGVNYIKNSPAVDSPEIAAVQACALDNKIAVSLGFSENENNSLYIAQLFIGEDGEIKVHRRKMKPSHMERTVFGDSLAHCLDSVGQLSFARVGGLNCWEHTQPLLKYNSMAQKEEIHVGAWAVNPPHTGGRDLWSTCLEGCHALSSVYAIESGTFVLHCTALISDAAVEKTGTASSLLQFNSGAGASAVFGPDGRRLTELTDPKEETILYADLDMDRILEARMFADPTGHYSRPDLLWLGVDKTFKSVVREGSGAPEVGVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIE8</accession>
    <name>X0BIE8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979365">
        <property type="protein sequence ID" value="EXK78209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIE8"/>
    <dbReference type="eggNOG" id="ENOG502SPQD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048766_0_0_1"/>
    <dbReference type="OrthoDB" id="3759773at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="453" mass="51759" checksum="B85F58FB65C393B3" modified="2014-05-14" version="1">MSSTVDIQSLPSEVLRNILFFVRNEKNGQGSIKECRLVSHCFDNAASPLLLTEVSVCLTSKSFTRLEDICYHPIFSKSVQKVSIVTSYYETELACNRPLFMLEAKARLLRHVETMERSRSYRNKYPHTQAQSRWLSNMAWRTEPEFEQLFSDQVDEESPTPTQRLFLKLYDLYKDLYNDQQQIREGQNHITRLCIALSSLSNLVSLELNDIRNMGGMEHLDVADFAHTGYDHTILQHFSPILRKSRWCGSFKTIHTATPPVEMLGTLCSELADKGLRPRTIRLRLVPPPNMQAWQLSPSQQTGLKNLVAQTTKLALYVDFGARSFELKDNPRHEMLALCSITQSCMSAPHLEDMHVGFIGYPPLNMRPTVSLDDILPVNLSWPRLQSLSLHNQPFTVMELKSLVARHSKTLRDLQLQACWLLEGSWVDIEEVVQGEHAPEKSSIKYPQGGNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIG5</accession>
    <name>X0BIG5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Subtilisin-like serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658534">
        <property type="protein sequence ID" value="EXK78229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIG5"/>
    <dbReference type="HOGENOM" id="CLU_043687_0_2_1"/>
    <dbReference type="OrthoDB" id="5086500at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046536">
        <property type="entry name" value="DUF6601"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414:SF1">
        <property type="entry name" value="SUBTILISIN-LIKE SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20246">
        <property type="entry name" value="DUF6601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="41207" checksum="7796DB9F6CAF9668" modified="2014-05-14" version="1">MADFQNGGGQSPPFSLRLLKLNDGQDAPSSQVDNHQLMLLLPATYRTNSNDLAAPNRHVIDCIKTELALQRLNRVSGWLWVAGRLAPPRPLHHQLLLSREIFITEQIDMHLVWTTGRVFVKPIPRFLLEPCFWTEYLSCGQGCDCSIGEAHSRGSIPECERRELWKCALGFLFSYAALISHESDFLLAKEKNLLPEEVTWPGWISFVEQLDTEHIYPDIDSRFYHGELRLSRLNKIHRLFQTPLHGYMAHWNQYATFFRDNFAWLGGTTVYIAIVLTAMQVGLATDTLAHNDTFQSASYGFTVLSILGPLICAGLIVLAFCFIFIYNWIMTVTQKRERLRHIQRDESRIRHFTAPQATCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJ02</accession>
    <name>X0BJ02_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_13798</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658421">
        <property type="protein sequence ID" value="EXK81816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJ02"/>
    <dbReference type="OrthoDB" id="4456959at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF23">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK81816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="782" mass="87090" checksum="673A5A1E8BF6E91E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BL86</accession>
    <name>X0BL86_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aromatic-L-amino-acid decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_12753</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BL86"/>
    <dbReference type="HOGENOM" id="CLU_011856_0_4_1"/>
    <dbReference type="OrthoDB" id="2161780at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF70">
        <property type="entry name" value="MIP05841P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK82920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="36472" checksum="E85E06B3D5859E04" modified="2014-05-14" version="1">MARHQKLGNDLRARALGVAYISDQAHFCIKKGLHIMGLFPEQIRVLPSDIRGCMKISELRKAVQDDVQKRKLPFLVVATCGTTNTGGIDQLGEIADLAETFGMWLHVDGAYGASVSLCQPRRHLVRDLARADSVAWDAHKWLFQTYGCGIVLARNKAHLRTTFATTAYYIRDLDIQEERPNLLDYSMELTRPARHMKLWFTLQTLGLDVLSSMINQGFETAELFEQHLRQMPSWEIMSPASLAILTFRCHPQGWSDIKTDQLNESISLELRKNNIALIATTKIGDAVCLRACMINNTITSQDIAEICAALDRTAQRCGASPETNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNH1</accession>
    <name>X0BNH1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lignostilbene-alpha,beta-dioxygenase isozyme III</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_12414</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNH1"/>
    <dbReference type="eggNOG" id="KOG1285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016472_6_2_1"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF89">
        <property type="entry name" value="CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK83401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="588" mass="66695" checksum="E0E83E2BE0D01DED" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPM4</accession>
    <name>X0BPM4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658445">
        <property type="protein sequence ID" value="EXK80424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPM4"/>
    <dbReference type="HOGENOM" id="CLU_3014232_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="56" mass="6110" checksum="F337B58B2DBA32B7" modified="2014-05-14" version="1">MGRDLFLRKSNRFLPDYGSFGKGSTYAKLLKVAPSKNSVKKATQTEKGEERASGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQE4</accession>
    <name>X0BQE4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Pisatin demethylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14806</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658438">
        <property type="protein sequence ID" value="EXK80669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQE4"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK80669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="58500" checksum="9BF0AC260B414113" modified="2014-05-14" version="1">MITQSSPTELSYVGTAVVLFAVLLWWIISALTSPLRTYPGPLFAKWTNLWRLYQVRTQKYQWTIQDLHKKYGPIIRIGPNLLDLDYPELIKIIYGTDHRWLKTQFYLNNSSMVDGKIKHNLFSTTSPAEHAQMKKPMAKYYSSSNVLTMEVKMNQVIEELCKQIDNRFLEDDKSFDLAEWLGLYTWDMIGSLTFSQPFGYMKKGHDFDGTIIASALSVDYFAQIGQMPFLDWLLNKNPMVRVGPPDMSHVTHFSIAQLQRRLEQQEQRKSSEEPDFLDYFIDGMKSNPDSVDAKLVLNFLLANVLAGADTTAIALRAIFDFLLQNQHAMTKLKSEILTLGFHDAEAVPYSRARSLPYLDAVIRESLRMHPSVAMPLERYVPNTGLMLPDGSFVPPGASVGLNPYIIGRNEKVWGKNADEFRPDRWLKAEDESEEEYQRRLRNMNGADLTFGGGSRICIGRHIALIQIYKAVATLVSRYDIQLADQNVRMKIISGWFPRQTGLFVRMRKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRD4</accession>
    <name>X0BRD4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_11243</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRD4"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_11_1_1"/>
    <dbReference type="OrthoDB" id="3357846at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015244">
        <property type="term" value="F:fluconazole transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF23">
        <property type="entry name" value="FLUCONAZOLE RESISTANCE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="469"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="129"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK84720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="569" mass="61883" checksum="7FFB388E9D13D4F3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRW4</accession>
    <name>X0BRW4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658428">
        <property type="protein sequence ID" value="EXK81194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRW4"/>
    <dbReference type="eggNOG" id="ENOG502R6VN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042442_1_0_1"/>
    <dbReference type="OrthoDB" id="5598695at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000087">
        <property type="entry name" value="Transcriptional adapter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF21">
        <property type="entry name" value="SWIRM DOMAIN-CONTAINING PROTEIN FUN19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIRM" evidence="2">
        <location>
            <begin position="315"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="417" mass="46668" checksum="F4A3B5279A3DBE8A" modified="2014-05-14" version="1">MQPSTTFDDNTISSVKLQTERTSSLPSIQSLPFHYSPSGPSNSTNNTTTMAANSPHNAQATSAMPPPAHPASTPSKMHINSLMSPPDQAHDSFYYHTGKVDDSSKNASGKPPMSPPISPCNRPMATTETPTNSIQDPVLYPSDEVPSSPAQTPLFPTLEDRDHSRTIEEHMQKNINDKIFVEVQPPTRNDYELVASFQSQLNKNYELNPKAWMLSVNKQARDDNRRIAQAKARARPLAAKAAKISRPRPDNRVQKPTQRFIRAQPTNSPKRPTPQLSANGTAEPKPRAQGPDKDFESLPDFCPPLSTLPDRSTILKVDWKGQPLDNSNDPHRHLLHPDELTLASNLRLDCATYLASKRRIFISRLSCYKRVKDFRKTDAQQACKIDVNKASKLWTAFDRAGWFHKGFMEPFQNTKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BT38</accession>
    <name>X0BT38_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BT38"/>
    <dbReference type="eggNOG" id="ENOG502T60G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1635455_0_0_1"/>
    <dbReference type="OrthoDB" id="4980216at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936562" evidence="1">
        <location>
            <begin position="18"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="157" mass="17396" checksum="BB8F542F8A3B85A9" modified="2014-05-14" version="1">MFAQAVLLIAFACNVSGTPYVVTDPKDLHSTWSSDDYKATHDTHSIRWEFTVKGRNGVPGPGNFAASCHGLQVISDDLDLTGKPDFERCNDTAYEARQYFSGEYTTVEVRRTDYPDLGKEVQISATANYTSTNDNIVNGHLKFGDFQTKFISTPIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>X0BU81</accession>
    <name>X0BU81_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_13575</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BU81"/>
    <dbReference type="HOGENOM" id="CLU_003864_3_0_1"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000264">
        <property type="entry name" value="Zinc finger protein 236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF3">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="588"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK82059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="822" mass="92486" checksum="740020D0AF659F4C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVC7</accession>
    <name>X0BVC7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MACPF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVC7"/>
    <dbReference type="eggNOG" id="ENOG502RMUD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057547_1_0_1"/>
    <dbReference type="OrthoDB" id="4500473at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="31066" checksum="411E0A74504D60D1" modified="2014-05-14" version="1">MVSSTSPKPSYHLCPDFSIAPPPDGHLTLGSVLESLDVDGVAHPLNLNAAIEIPAEHIFPRNGPDSKTGFTRTLKELRSVEASIWAKIFSLQGLGGTFNFLNKRTDDESLTVEEIQTRYFSPTEEYMTKSLELPDVASFVTVTQKKFPVYMVTGLKVAIGAKLSRVESKTKNVKAEIGASDPQGMVSAGGTGGYTSEDVSAMGFDGSTPFVLGIRVRKIWWEKGVRKTSDKVAGVALDNGGAQDKVSPVSGARFVEDFLVDDGEKPPAGKVFANETDDLGIEPSNWALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ49</accession>
    <name>X0BZ49_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">O-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_09257</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Sterol O-acyltransferase that catalyzes the formation of stery esters.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ49"/>
    <dbReference type="eggNOG" id="KOG0380">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018190_2_0_1"/>
    <dbReference type="OrthoDB" id="10039049at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034737">
        <property type="term" value="F:ergosterol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008204">
        <property type="term" value="P:ergosterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF9">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000439">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="447"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="584"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="271"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="294"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000439-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK87465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="607" mass="68900" checksum="0671EDB20AC1B293" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZI8</accession>
    <name>X0BZI8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_08933</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZI8"/>
    <dbReference type="HOGENOM" id="CLU_022435_0_0_1"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07216">
        <property type="entry name" value="Pat17_PNPLA8_PNPLA9_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="234"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="4">
        <location>
            <begin position="238"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="272"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="4">
        <location>
            <begin position="420"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK87595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="578" mass="64315" checksum="F574B6ABA45D0F79" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZQ1</accession>
    <name>X0BZQ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979648">
        <property type="protein sequence ID" value="EXK76012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZQ1"/>
    <dbReference type="HOGENOM" id="CLU_010595_1_2_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="38615" checksum="289DB623D105816D" modified="2014-05-14" version="1">MLGKMATIGADPVIHIDVDDDRDSAAGDDNASSTASVTSSILNYRFENGRTYHGYKDGKYYMPNDETENDRLDLQHNLFLLTFDNKLGLSPPNLPDFKTGRVLDLGTGTGIWAIDFADEHPEAEVIGVDLSPTQPEFVPPNLQFEIDDIDEEWTYSLPFDYIHSRMMNVSVKNWPEYLRKIFENLTPGGYAELQDVDIMMQSDDNTLTQDHALWKWGFFLAKAGQEHGTPFIETNRLKHIMTEIGFVDVKETPFKWPSNHWPKEKRFKDLGAWSNLNTVNLLNGLSMALFTRCLGWTPEEVNVFLVDVRKDLNNPKIHAYWSMYFLPPSVLLSVLILC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C043</accession>
    <name>X0C043_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynactin subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08663</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C043"/>
    <dbReference type="eggNOG" id="ENOG502S7GK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085418_2_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027777">
        <property type="entry name" value="DCTN6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072">
        <property type="entry name" value="DYNACTIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072:SF0">
        <property type="entry name" value="DYNACTIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK87760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="194" mass="20923" checksum="FDCED04273D97DC8" modified="2014-05-14" version="1">MSSKRHSILPAIDRSGPRPPVHFSDSLTISDNAILQGTHSITIQSETVVHPRSKFESNSGSILIGRRCLIHERTHLGTRPVDPDTAQRGGIVLADFVTIEAGSIIEAGNTEIGEGTVVHAGSTIGSGARIGKNCTITQMTKIAPGTILPDNTVVFSNGTRRIDRRNLADQRKIALMKQLAVLRKMIPSNADKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0C085</accession>
    <name>X0C085_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">poly(ADP-ribose) glycohydrolase</fullName>
            <ecNumber evidence="2">3.2.1.143</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_08718</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the poly(ADP-ribose) glycohydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.143" evidence="2"/>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C085"/>
    <dbReference type="eggNOG" id="KOG2064">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013388_5_0_1"/>
    <dbReference type="OrthoDB" id="1937899at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004649">
        <property type="term" value="F:poly(ADP-ribose) glycohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990966">
        <property type="term" value="P:ATP generation from poly-ADP-D-ribose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046372">
        <property type="entry name" value="PARG_cat_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048362">
        <property type="entry name" value="PARG_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007724">
        <property type="entry name" value="Poly_GlycHdrlase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12837">
        <property type="entry name" value="POLY ADP-RIBOSE GLYCOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12837:SF0">
        <property type="entry name" value="POLY(ADP-RIBOSE) GLYCOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05028">
        <property type="entry name" value="PARG_cat_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20811">
        <property type="entry name" value="PARG_cat_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PARG helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="PARG catalytic Macro" evidence="4">
        <location>
            <begin position="231"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK87825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="475" mass="52602" checksum="DE5D85056B3DEA55" modified="2014-05-14" version="1">MSSRPQFFHLPNSVSCRILDRFSDLPDDAEVEEDENGKIPFWPLLKHLLCTPVSSIAQLIDRLQTIAANTETCQDSDYGFLKRFLERGEADILDTIWPKIRDIALALPIYFPDGKLELLQPGHPLHLSRGQVACLVVHQFLCSFTPQRDDEGYQDLGIWFSSEQRHPTAVQMYLEALFTYFGSTLEASALLEDHQVTPNGAHGSVSYELHLGNPVSLEGTKLAKLHVNFLDAHTSDTHNPEVQDEGGAAVVSSNKVIGFGQSATQEEIFVGIAPEAYPVVLVAPQLEVDTVITVSGARAMVDMKGQRRNIEWTIRRTPPSEDFVGWKESWRGGRLVFMDALEMDMLDHSENNGLPDLSPENIDREIDKAANGFSSYQGNSIFTGLWGCGAFGGDPGLKLMVLWLAAGVADVELNLMLGPGEHDLGRKIKEVVKACQDLTATGVRELLSRVPRDLRREGILEWVANEASEAQHDTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0T3</accession>
    <name>X0C0T3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09051</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0T3"/>
    <dbReference type="eggNOG" id="ENOG502QSMN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008599_2_0_1"/>
    <dbReference type="OrthoDB" id="3364175at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="100"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK87711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="697" mass="78188" checksum="2155C455E854B32C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2D9</accession>
    <name>X0C2D9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658659">
        <property type="protein sequence ID" value="EXK76957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2D9"/>
    <dbReference type="HOGENOM" id="CLU_906268_0_0_1"/>
    <dbReference type="OrthoDB" id="5106806at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="307" mass="32109" checksum="C49DE8962E2B0E61" modified="2014-05-14" version="1">MGRAASEPTGLPQQTQPGPTGFRTLTSPPSIPTGNTVKLNLNDAELGPHATFIQIGGEEAILLTAPPNGEANFTLKVKKPLGIAPGSLVRLRASIRVEEIGATNPHVRSLFRRENTGNRLQMIMDEKTIYDKEVKATAGKFEQVQSEKTTFSDNPIVEVVQKAGKNPVALTVRGLSFVKSAGPTKEPTIPPEEPTIPPEEQTIPPEESTFPTGEPTFPAEVTGTESVSGGQETTVSGGTGKSGGGKESGSYSSVSNLESETGTGTPTRPVSPTTPGPVQIIPNEGGHCLIMNTIAVYGVPLIAAILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0C300</accession>
    <name>X0C300_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_10611</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C300"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000023">
        <property type="entry name" value="Sensor histidine kinase/response regulator, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF72">
        <property type="entry name" value="OSMOSENSING HISTIDINE PROTEIN KINASE SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="563"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="1104"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="268"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="452"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="997"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1000"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1011"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1031"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1052"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="1166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK85548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1235" mass="136510" checksum="DE20FA0A04A5A0EE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C341</accession>
    <name>X0C341_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C341"/>
    <dbReference type="eggNOG" id="ENOG502S0HA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022730_0_1_1"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF279">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="37"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="464" mass="50224" checksum="E6C570026E744759" modified="2014-05-14" version="1">MSTSGFPVEGSPQSYWQHEAQQPEIPSNTGPLPNSCDVAIVGGGYAGIATAYHILKTTSPPRIVFLLEAKDPCSGATGRNGGHLRPDYLMGAARNCKKYNASAAAEIVQFEARHLDVIKSLIRSEAIECDFAETESLAVLTTLEQVSMVREAYEGLKQASSFSDTLLDVIEFYEGDDAPQRTGLRDAKGYFSTPAARVSPYKLLTSLLARCVDMGLSLRTQTAVVSVEHAGSDGHTLMMRSGETMTAQKVVIATNAYTSAILPEYASSIVPCKGLACHIIGPKGKPLPKLLAASCAIMEQDSVSNKTGYNYMVQLEDNSIVLGGAHHKYDGNDLGSWYNNVNDTQLIEPARRYFEADYMQRTFVGWEDSGACVDRVWTGIMGYSTDSLPHVGEVPGRDGVFIIAGFHGHGMPVIFLAAEGIAAMTQGLAYEKTGLPSLFKTSRDRLESKRNDILVGRGIRSTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0C346</accession>
    <name>X0C346_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08117</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C346"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="198"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK88830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="268" mass="29156" checksum="E1275E7D76384E11" modified="2014-05-14" version="1">MEELEGCVLFASPKQQETQRLRERNRTAKRASRARQRQREQHNDTTADVATAEATAQDVDVAPPLQPPLHPDSGSGSGSDSVCVRAEASEDFGVWALDGPLDDPTALPWLSSLDEDWPGFSGSLVDTLSPRQLSVSVPGRCNPEPRAPPASSSSLTSNSNDFNSKPLRLLHIAARNGTTGILLSLIKAGADVNSRDCSGTTPLHIAVRFRRASALELLVSHGANMKARDSANMTALEGAVRAQDEEHSLLETDNSFWYPGWQYNWMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C451</accession>
    <name>X0C451_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C451"/>
    <dbReference type="eggNOG" id="ENOG502SNVF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_22_1_1"/>
    <dbReference type="OrthoDB" id="10255422at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009725">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33990:SF2">
        <property type="entry name" value="PHNB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33990">
        <property type="entry name" value="PROTEIN YJDN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021700">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PhnB-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="166" mass="18536" checksum="2406E0E6AADDB266" modified="2014-05-14" version="1">MSFGKLTTCLWFEDQGEEAANHYVSIFAPDSKINSIQRYTPAGQDQHGQEPGRVMVVEFELRGRSFVALNGGPAKWKFSEAISLMIDCKDQAEVDHFWEKLSEGGDEARQQCGWLADKFGVAWQVVPSALKEMMGSEDKAAAGRATMAMMKMKKFDIAELEKAYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C585</accession>
    <name>X0C585_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C585"/>
    <dbReference type="eggNOG" id="ENOG502SQ9B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018058_0_0_1"/>
    <dbReference type="OrthoDB" id="5399183at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="574" mass="63956" checksum="684F33CBFAAA2754" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5M2</accession>
    <name>X0C5M2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5M2"/>
    <dbReference type="HOGENOM" id="CLU_2145950_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="119" mass="13564" checksum="8BFB3DDAAC2557CF" modified="2014-05-14" version="1">MFMWSWNLEMPSRSGPGVGQGASQTVMLCYPVSKPDDMVLLLCVCIFTYLSGRVVHFTVICCPFTVIASDHTKHHNCRIDLIIIQHKNPHQDTKRSPRRTVGLPNHRLTNFSWTDHLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5R9</accession>
    <name>X0C5R9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658546">
        <property type="protein sequence ID" value="EXK78092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5R9"/>
    <dbReference type="HOGENOM" id="CLU_010672_3_0_1"/>
    <dbReference type="OrthoDB" id="2156052at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030277">
        <property type="term" value="P:maintenance of gastrointestinal epithelium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000813">
        <property type="term" value="P:negative regulation of barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052853">
        <property type="entry name" value="Actin_dynamics_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47574">
        <property type="entry name" value="CANCER-RELATED REGULATOR OF ACTIN DYNAMICS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47574:SF3">
        <property type="entry name" value="CAPPING PROTEIN-INHIBITING REGULATOR OF ACTIN DYNAMICS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="589"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="778" mass="89830" checksum="F5D89A9D1E52C9AF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C630</accession>
    <name>X0C630_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658541">
        <property type="protein sequence ID" value="EXK78167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C630"/>
    <dbReference type="eggNOG" id="ENOG502QZKU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065839_0_0_1"/>
    <dbReference type="OrthoDB" id="3596450at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="9"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="338" mass="38528" checksum="375F6ABB6B34BC0D" modified="2014-05-14" version="1">MISRMFDSFHCFTNLPVELQIEIWSSAVRPAKAGVQIFSLSSDHRSQPHEDGAPEAPWVGSYDLTAPRWAFGPKSSRVNGFDEITASWTKNNPSTYLLDSGVWNACRQSNRVMRDVLGPTKPIAIRTKVRCGRSDVEVDAPESDSSQQRSIIVSPSQDLFILQPDGPDMFSRFLFEDVIPNNTAQGLLQIPHVGWQYHPSWASSLHESPRIRSLDSLCYYIVYGARFGGLETIWLINYRIKRKHWVSSKAEFDGPKPKVFKTDEFQLIEVEIDNDIRSSEQLSWDEVVERGDPYTLDDFLAFVRQLRQLVTHTLLSTPAPYTGRHAMSIKVLAYEDFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6S9</accession>
    <name>X0C6S9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6S9"/>
    <dbReference type="HOGENOM" id="CLU_180198_1_1_1"/>
    <dbReference type="OrthoDB" id="4971741at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="77" mass="8699" checksum="7FCD08E011EBB756" modified="2014-05-14" version="1">MPMINRIREDTEVWKCMRTKSDGTICPGATEPAQMLCEKCGLKRTVGSIANNEDGKKIGELKKVEDTGIEHWEFNDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7C1</accession>
    <name>X0C7C1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979354">
        <property type="protein sequence ID" value="EXK78622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7C1"/>
    <dbReference type="eggNOG" id="ENOG502SRGH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067182_1_0_1"/>
    <dbReference type="OrthoDB" id="5620at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="253" mass="28389" checksum="7A9C944221AF73A6" modified="2014-05-14" version="1">MPRNFQFVTVSNPTEPVPSHVRSLTHSHAVRQRHAKERRLRIQKHQEDMSRNAERTSLNKLLGYGRDPFDALPKQLLSHENFLLDHYVRVVVPYNVKTCRLFNQMNDHEAKVMRDWVGLAITDSDLLCSIIFLGACRHILISNPKSGLTQVALQYKYNGLKALRHAVSGASPIVSALTIAKACAMALDEVNFGEATVARQHIQGVFAMIEAAGGSECLDGTGLLKRMYLRFLEMREGPGLQLPKGIAYSSHCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7Y4</accession>
    <name>X0C7Y4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658500">
        <property type="protein sequence ID" value="EXK78822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7Y4"/>
    <dbReference type="HOGENOM" id="CLU_035253_0_0_1"/>
    <dbReference type="OrthoDB" id="21416at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="564" mass="63569" checksum="AE3CC884AAB7DF81" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C807</accession>
    <name>X0C807_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C807"/>
    <dbReference type="eggNOG" id="ENOG502SHP9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_13_3_1"/>
    <dbReference type="OrthoDB" id="5819582at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF125">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="68"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="501" mass="57938" checksum="35BC13B356DEEECA" modified="2014-05-14" version="1">MSPRTSGLLDSDDWDEVKTDSSSDWTLAKSYSSWKPAAAGGKLKHIINTTRAAIRARTRPLENLRPTAYLDGLRGFAALLVYFHHHELWVRDVVGQKPILENSFGYGGKHYFASFPFIRHFFTGGHYAVSTFFIISGYVLSLKPMGLIQSGEHAQLGDVIASSLFRRWIRLYLPIIMSMLVYITLLHMFGVWVRIMTQQKSWYDELWAFYYEFKNFSFVFKEGGEPWLTYNRHLWSIPIEFKGSVVIFTAQMAFSRCSKNARLWCETGLIFYFMYIADGSFYSMFTAGMLLCDLDLLASKGDLPRWMARLEPAKEFIFYHLLIFSLFLGGVPSENRNVEQLAKNRGFYYLSWFKPQAVFDYKWFYLFYASVFLVASVPRIFWLKSFFETRFCQWLGRISFALYLVHGPVLWTIGERFYVAAGWQNEEIMKNIPHWANKLALPMSGPLGLEISFLLPQLILVPLTLGLADVVTRFIDTPSVKFAAWFYKKALGDPTSKQAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C812</accession>
    <name>X0C812_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_09333</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C812"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF1">
        <property type="entry name" value="ALLANTOATE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="461"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK86969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="58217" checksum="A29FC3559BD6144F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C887</accession>
    <name>X0C887_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribonuclease P protein subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_07147</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C887"/>
    <dbReference type="eggNOG" id="KOG4046">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078577_0_0_1"/>
    <dbReference type="OrthoDB" id="124041at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.210">
        <property type="entry name" value="Ribonuclease P/MRP, subunit p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016848">
        <property type="entry name" value="RNase_P/MRP_Rpp29-subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036980">
        <property type="entry name" value="RNase_P/MRP_Rpp29_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002730">
        <property type="entry name" value="Rpp29/RNP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01868">
        <property type="entry name" value="RNase_P-MRP_p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027081">
        <property type="entry name" value="RNase_P/MRP_p29_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00538">
        <property type="entry name" value="POP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="Rof/RNase P subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="33"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR027081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK90331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="228" mass="25368" checksum="410C71C832BF243E" modified="2014-05-14" version="1">MASAPQQATQNLLARAHSPDSVNRIYSEKIQHRSLILRPTSPPPSTINARAARRKARQDKKEKQKQRPKPLSSREKRSLGLHDIPKDGQKYHIYEPLSQMWLGYARELLGNDLSTGGPSAAAKLASAEFHGAPIQVVRSHCPSRVGIQGVVVRDRKFVFEIITKKRGVKVVPKEGTIFRVEITINDGASDGESGQNKKFACEVLGDQMMLRAADRANKKFKAHFLSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9P7</accession>
    <name>X0C9P7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">N-alkane-inducible cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_08910</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9P7"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_27_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF18">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE APDE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0349">Heme</keyword>
    <keyword evidence="8 11 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK87569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="58948" checksum="1CBC5BB6DEBAE9DA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB27</accession>
    <name>X0CB27_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alcohol dehydrogenase (NADP+)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_15555</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658455">
        <property type="protein sequence ID" value="EXK79877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB27"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_0_1"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000007">
        <property type="entry name" value="NAD(P)H-dependent D-xylose reductase xyl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="338" mass="37509" checksum="8333698821300B8E" modified="2014-05-14" version="1">MSQGKTFTLNTGAKIPLLGYGTWQASPGEVGQGVYEALKVGYRHLDLAKVYGNQPEIAEALKKSFAEIPGLKREDVFITSKLWNSQHDPKQVEAALDDCLQELGLEYLDLYLIHFPVSFKNSGAPIGQDLFPLTGGNQPDGDVVIDDSISIVDTWKAVTELPKSKARAVGVSNHTKEHLEAIIKGTGVVPAVNQIERHPLLIQKDLIDYCKEKNIHVTAYSAFGNNMVNAPLLFTYPEIKAVAERLTKEKGQPVSPTQVLLAWAQVGGHSVIPKSVTPKRIAENFQEIDLSEDDIREIEQVGKEQRRYNVPYVANKPRWDVNIFGHEDEKPATHQVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBC1</accession>
    <name>X0CBC1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBC1"/>
    <dbReference type="eggNOG" id="ENOG502T154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076163_1_1_1"/>
    <dbReference type="OrthoDB" id="5289641at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39697:SF2">
        <property type="entry name" value="CYANOVIRIN-N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39697">
        <property type="entry name" value="RICIN B LECTIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="166" mass="18904" checksum="21351B2C39F7B3FE" modified="2014-05-14" version="1">MSKEMDLIDTMSMASTVDSQGTPTHTTTTEHCRDYTESVPYPGAIFIIRHRDSGKVITIVNGDLRLCEGFNPRGGFHWECIERDRWLGFRNCVSGTIIGHNERKKFIARVDKHQSHEYFTLRPSPQGGYELLMRHGQELWSMAVGDDGSELVEVRGEGALWDFLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CC67</accession>
    <name>X0CC67_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08098</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CC67"/>
    <dbReference type="HOGENOM" id="CLU_063916_3_1_1"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="WSC" evidence="7">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="7">
        <location>
            <begin position="82"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK88808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="200" mass="21918" checksum="8B11B3B29CD9CFE5" modified="2014-05-14" version="1">MTLESCASFCSGFIYFGTENSRECYCGNQLNFGSIQALNQKDCSATCAGDKTDYCGGTLRLQLYKAGAKTTTTPSVDQGNKNFTSYSCVSEPFLGRLLPQLVMSDGNSMTIDTCLEKCWMYKYAGVENGRECWCGNNINWQGLLPNFGQGKNVSMTDCNIGCPGNNLAYCGGLARMNLYINKSSALAFLKKHKRRHAKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCF6</accession>
    <name>X0CCF6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent DNA helicase CHL1</fullName>
            <ecNumber evidence="18">5.6.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-dependent DNA helicase chl1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Chromosome loss protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19 20">DNA 5'-3' helicase CHL1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">FOQG_06491</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21">ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="18"/>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCF6"/>
    <dbReference type="eggNOG" id="KOG1133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006515_2_0_1"/>
    <dbReference type="OrthoDB" id="267079at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034085">
        <property type="term" value="P:establishment of sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001372">
        <property type="entry name" value="ATP-dependent DNA helicase chl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002774">
        <property type="entry name" value="ATP-dependent DNA helicase chl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF41">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE DDX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="24">
        <location>
            <begin position="14"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00044998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00045008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00045702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="EXK91826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="864" mass="96309" checksum="8B1EBEB1D7270BD6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDL5</accession>
    <name>X0CDL5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YCII-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDL5"/>
    <dbReference type="eggNOG" id="ENOG502S8X0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110355_2_4_1"/>
    <dbReference type="OrthoDB" id="5519740at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1060">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051807">
        <property type="entry name" value="Sec-metab_biosynth-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606:SF3">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII-related" evidence="1">
        <location>
            <begin position="38"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="140" mass="15750" checksum="953D48A693116361" modified="2014-05-14" version="1">MNSRLAFSLSRARITPRFTTFRTMASSSVTVPPGKYEFLVVVHDKPNVREKRLEVRGTHFKNMVPNVENGSWKMGGAILNSVPKDDSVDSLDFAGSTLVCIAESVEEVREQLSKDIYATSGVWDMDKVQIYPFKAAFRMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CER8</accession>
    <name>X0CER8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658429">
        <property type="protein sequence ID" value="EXK81132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CER8"/>
    <dbReference type="HOGENOM" id="CLU_009785_0_0_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="912" mass="103225" checksum="96922F9B61A9DD57" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFE7</accession>
    <name>X0CFE7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 16">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="6 16">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_07649</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. Both L- and D- forms of purine and pyrimidine nucleotides can be used as substrates, but the activity is much lower on pyrimidines. Negatively regulates the biosynthesis of acetyl-CoA from pyruvate in the mitochondrion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 17">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="6 16"/>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFE7"/>
    <dbReference type="eggNOG" id="KOG1367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025427_0_0_1"/>
    <dbReference type="OrthoDB" id="275353at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1260:FF:000003">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1260:FF:000019">
        <property type="entry name" value="Phosphoglycerate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="entry name" value="Phosphoglycerate kinase, N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406:SF0">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="11 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00016471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK89554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="516" mass="55983" checksum="6535EE7CFD04BFC6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CG20</accession>
    <name>X0CG20_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_13993</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658425">
        <property type="protein sequence ID" value="EXK81577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CG20"/>
    <dbReference type="eggNOG" id="ENOG502SMIC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_0_1"/>
    <dbReference type="OrthoDB" id="5417887at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF147">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="41"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK81577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="425" mass="49172" checksum="2A50B30D7BEB5086" modified="2014-05-14" version="1">MKLRLRDDQDDGPVHTFVNPYVELNAGLWSLFAGATFFLWLRLYVKITRRHGMWYDDYILLVSWFILLANNSLIIWEFNNGYVLKDSSQQWDDRMHILINVSSCGTLIGQALTKTAFAVTLLRMSNRWQKWILWFCIASMNAYMIVKVFFQWAKVCGKPTYDNWYRFDFCLDSKFRNDFKEGGNIYNIIMDFVFACFPWLITRGLEMKKAEKIGLCFTMSLGMIIAIVSAIRVSWKDQGNGRDAYYIWRNGMSQVWYSSEVAGTIMVQCIPILRPILKKFHTSYTSRRLDSQTGERKGSGWTWTRSSKHISTGPLTPGHPPILNNNPDGMELRNIPEEQEPAEFDFWGKNDPPSPDDLEDGRPDIKYKFNREEMKFTRDDSWPLGGESESAKSARSIELAHSNMGLAVEHEAAQQGLSPPPPRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CG89</accession>
    <name>X0CG89_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07088</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CG89"/>
    <dbReference type="OrthoDB" id="1939603at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="266"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK90248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="419" mass="45654" checksum="48D8FF43430475AA" modified="2014-05-14" version="1">MSLVPTQQPHTFVDNHASLHSASNIAKLGSEATLDTLLSSPNSMERSATEYSQSGLPSPYPSNFGDTNSEGSRADHASAAQYPVKQEVNYSTSATPTSEYGVYPQSARSGSFPEHVQRSYHPASSTSTGGMAQQQNSPSMPQQDGRSHQTHPVKSDNDVPIDPSIAAPSPTYASYGQHSPYAPNPDMTHSYSHPGGGMYAQPRPDWAGYPQHGGAPLTPGHPVYAQNPASAPPQARPNQVYSFVPIPGAQQHKRPRRRYEEIERMYKCGWNGCEKAYGTLNHLNAHVTMQSHGQKRTPEEFKEIRKEWKQRKKEEEANRKAEEERQRQAAAAAAAQNGGGDPQGPDGTPTSSYPGRTVQLPPIGYQPAQYPPPPSGVPQQPLPDYNNSHMYSNYQPHSPYAQPSQGIPYQSNGGQPPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIA9</accession>
    <name>X0CIA9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ER membrane protein complex subunit 7 beta-sandwich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_05081</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIA9"/>
    <dbReference type="eggNOG" id="KOG3306">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073620_0_1_1"/>
    <dbReference type="OrthoDB" id="27095at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019008">
        <property type="entry name" value="Beta_sandwich_EMC7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039163">
        <property type="entry name" value="EMC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605:SF4">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09430">
        <property type="entry name" value="EMC7_beta-sandw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939429" description="ER membrane protein complex subunit 7 beta-sandwich domain-containing protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 7 beta-sandwich" evidence="9">
        <location>
            <begin position="34"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="185"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK93921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="242" mass="26226" checksum="0E5A7115EDB05C93" modified="2014-05-14" version="1">MRFTFETSAILALLPLALADSLTLYLPSNPNPFSIPANTHATLSSAGVHFSAPLSSANTFVFHNVTPGSYLADVHCPTDAFHPLRIDVQLAEDGEEGIVRAWETYRGNDWGNKGEVVQVKEGSKGRGFELRAIGGKNYFMERPQFSVFAILKNPMILMALVSLVLMVGMPKLMDSMDPEMRAEFEAQRKNSPLSAAMTGQSSGDNPLTNFDMAAYLAGSKPKESTPANNGGNGNTKNQGVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CID8</accession>
    <name>X0CID8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06563</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CID8"/>
    <dbReference type="eggNOG" id="ENOG502T6FV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026318_0_0_1"/>
    <dbReference type="OrthoDB" id="5217604at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="31"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK91043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="58753" checksum="71C9684D9F725CB8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIE4</accession>
    <name>X0CIE4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658415">
        <property type="protein sequence ID" value="EXK82347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIE4"/>
    <dbReference type="HOGENOM" id="CLU_013866_3_1_1"/>
    <dbReference type="OrthoDB" id="2991872at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF11">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="570" mass="64455" checksum="02FDC8E4565BAC15" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJ75</accession>
    <name>X0CJ75_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TAM domain methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJ75"/>
    <dbReference type="eggNOG" id="ENOG502QSKG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_0_0_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="42344" checksum="77D216958AC59364" modified="2014-05-14" version="1">MSTPPAAAASPKSEKSPAKNTAKSPSKSPSNSPPQHAQVNVGDTGILEPTHWQQLAEEENVNQDDDAHSLSEESLASSTDSVTSSIFEYRKLHGRTYHREIGSSQYWAANDERQSELLDINHHCLTLGIGGKTHLAPLDTEKITKALDIGTGTGIWALDFADEYPNVEVIGTDVSPIQPSWVPPNLQFEIEDCTQEWTFAPNSADYIHIRWLIGSIPDWYKFFREAYKTCKPGGWVESFEPSGIITSDDDTVKESSALGQWGKLFIEGAKKLGVSFTVYEEELQRKAMEAAGFVDIQQFEYKTPIGGWPKDPELKELGQFGKLAFLADPEGFVLFVANTIGWTESEIHVFLAHARREIHSGKHHPYYKQRVVWGRKPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CK18</accession>
    <name>X0CK18_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NIPSNAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_04581</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NipSnap family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CK18"/>
    <dbReference type="OrthoDB" id="10262843at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000004">
        <property type="entry name" value="NIPSNAP family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000037">
        <property type="entry name" value="NIPSNAP family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012577">
        <property type="entry name" value="NIPSNAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051557">
        <property type="entry name" value="NipSnap_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017">
        <property type="entry name" value="NIPSNAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017:SF17">
        <property type="entry name" value="PROTEIN NIPSNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07978">
        <property type="entry name" value="NIPSNAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIPSNAP" evidence="3">
        <location>
            <begin position="149"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="NIPSNAP" evidence="3">
        <location>
            <begin position="255"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK94536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="354" mass="40310" checksum="D4BF2F6CBF2EC6A1" modified="2014-05-14" version="1">MLSRQFARAAAVTPLAGVRALSSTAILNGRTPSLGDVNPTHAEVDKFSQKQKEFRDHLVEAQKKREASSLPSHPQSANVPFNASVEGSQNDHVGRSEEVKEPEPARKAGPLTNLIYGTKEGRELDAQLEASFSQVLARGKYVHSIVLHQVKPEKVDEYVDLVGKWYPKMANAPENKVNLVGSWRTEVGDCDTFVHIWEYQKYEGYHQSRYSITHHPGFADFDNKLKGLINSKNVSLMQEFSFWPTTPPRSLGGVFELRSYTLHPGNLLEWETHWRRGLKARREVMEGVGAWFVQIGDLNTVHHLWQFANLEERRGRREQSWQVEGWSDTVHKTVPLIQSMKSRILVPMPWSPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKN3</accession>
    <name>X0CKN3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_03738</name>
        <name evidence="14" type="ORF">FOQG_10008</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the histone H4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKN3"/>
    <dbReference type="SMR" id="X0CKN3"/>
    <dbReference type="eggNOG" id="KOG3467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109117_2_3_1"/>
    <dbReference type="OrthoDB" id="3919494at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000007">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0488">Methylation</keyword>
    <keyword evidence="10 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="13">
        <location>
            <begin position="28"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK86374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK95000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="103" mass="11370" checksum="9392CDB8AE0C52E2" modified="2014-05-14" version="1">MTGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISAMIYEETRGVLKTFLEGVIRDAVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN61</accession>
    <name>X0CN61_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN61"/>
    <dbReference type="eggNOG" id="ENOG502SS9Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114608_0_0_1"/>
    <dbReference type="OrthoDB" id="5068067at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="22964" checksum="7B76219989A3DF23" modified="2014-05-14" version="1">MPTMLGLTNDRSPHGLNAEESKFGGPSSQRGMELTPRQQNGSIVSGIEGSDFFNGGGKQKEHDADEESDEENLKTIKGRNLSAVKEMETLLWRALCDKPKTALKYIAKDAVMSNRFLFGDPVPRTADSDPSLEEEIKHCEEWLAYKMHDPQPVEIGLMAAAIGYKVTLFRQLDQGDGNFGMQTVQATCSSSWRQLASGDWELTSMFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN90</accession>
    <name>X0CN90_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN90"/>
    <dbReference type="eggNOG" id="ENOG502RPTM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_507178_0_0_1"/>
    <dbReference type="OrthoDB" id="5093989at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="537" mass="60744" checksum="A44E64B9872B0B79" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNA8</accession>
    <name>X0CNA8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNA8"/>
    <dbReference type="HOGENOM" id="CLU_043054_0_0_1"/>
    <dbReference type="OrthoDB" id="5103079at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="451" mass="50905" checksum="7482BD5E0CC1413D" modified="2014-05-14" version="1">MTDDIRNHYDIRGPKADIVAAILEGRPPQFSNRDARPGFDCLIVVLRRIFSHIMLGPVPVMDWLAASEEENPILRFAWGLFGDGKAEVESAMQARYRVFDDLSSKGLDHQGSFEELCNSSLMNKTFWSQPEFRLTGILVDLDTRMAVVVSKDELADTSLLKLNHVEHPGQPLQEVVNQFFGVIIKNGKKLLSPPHNPRIVRVVYTASPDDAIRFGYDKLRGLHVPTMEFDPNNPIHHVVKGWNGYSLMAVVRLKDEKYPTEFVRTYGDQGDNLVGEREPPSIVNNRWSINDQHGKYMLFYGIQPNDRKLKSTRFPEISLPRMTENDAKTMKRMERFLDSMMDKDSHQQLQLTPPTSSARKLQLTQGIQGGQRTDSRNAGQPVPSSQLEPEISHPASGDTGDGEPQPTQDGEIKKRKRKRANRKRRRDAQEDEAEGRQPPGPPQGPAPSATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPJ8</accession>
    <name>X0CPJ8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPJ8"/>
    <dbReference type="eggNOG" id="ENOG502T36W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061601_0_0_1"/>
    <dbReference type="OrthoDB" id="5236058at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="387" mass="44502" checksum="754C56C50A6AAC63" modified="2014-05-14" version="1">MSSRTSLRSILRAWFASDNSSDSEPDVRIESVRGECHQPNQNRRRQKREKNNPFRLPKKRTYCSHCHGANGYGDNDFSRREAKSKSHKDQHASGGQQHRLSEQLKPLPVVPRQRPPQARGQQSPSEDTSLHSQGHNQKHKRSNVVDTQINASKQLNQKKHGIHTLYQQEQEQGSNEAIFLSDDRSMNREAVSEVVDMIALRFSHIPYAVSGLAAMVYYGYEARPYKVSIVCPEHTRENQKCWAKAQGMIPIPRQRHVWGVATSDGIIQQIRVRFPYDFNEMHALKIGTAGSNPVSMLSLAGLADELARTYVNELKHSDHDRQENLAHEMIWILKRIIQCRLPEHALRPERIPHLIRETFWLPFTLSYPESVPLFAKAGWSIPNEGWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPY6</accession>
    <name>X0CPY6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPY6"/>
    <dbReference type="HOGENOM" id="CLU_120090_0_0_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609:SF1">
        <property type="entry name" value="RFEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609">
        <property type="entry name" value="RFEG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="196" mass="22353" checksum="9AAD44F5B690934F" modified="2014-05-14" version="1">MTQSTSQYQRHVGRHQEQLALFALPTVESDEKNEGGSESDSSAESMDMISNQDERGDNNIQPDEPTTSSSMHRTDGITDAPWPRYSPNTRMKNNQNEYFAPRDGIDREVITADIHLHLGRDALVRPGVYEDPETGQEIQGYYIMASRNLTSAMIEDLKADSAQWEQEVRAVPRNRLGQGRYRDSQIHRNRVVYGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRD3</accession>
    <name>X0CRD3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate system cyclin PHO80</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRD3"/>
    <dbReference type="eggNOG" id="KOG1674">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023749_0_0_1"/>
    <dbReference type="OrthoDB" id="337735at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF117">
        <property type="entry name" value="PHO85 CYCLIN PHO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="348" mass="37918" checksum="22EC0F77683F75FE" modified="2014-05-14" version="1">MLKTSPALSASANASPTAFRYATSSPQHSSKPSPALRRRPSTRSDTPSSADAMKSSPIQRPRQYVANDSGIHGSPEVQRPPSSISQKASAHPAQSPAPSRPSQDQTVQQGQALSGVSPTKRRSSPTPTNPDAVAATNSSPQTSKRAKPATPPPKVLPDRYELCAIEDMVELVAHMLAELIATNDAIRISNGGLTRFHSRTAPGISVRDYLHRLARHATLTPPLLLAMVYYIDRLCAMYQEFTINTLTVHRFLITAATVAAKGLSDSFWNNTTYARVGGVRVAELKLLELEFLYRVDWKIVPNPEVLVAYYKGLVERTPGYVLESDGSDDEDEDEDDDAEDGENEPLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS03</accession>
    <name>X0CS03_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative phospholipase</fullName>
            <ecNumber evidence="4">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_10649</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30909"/>
            <dbReference type="ChEBI" id="CHEBI:36707"/>
            <dbReference type="EC" id="3.1.1.47"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the serine esterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.47" evidence="4"/>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS03"/>
    <dbReference type="eggNOG" id="KOG3847">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022501_3_0_1"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016715">
        <property type="entry name" value="PAF_acetylhydro_eukaryote"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF11">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018169">
        <property type="entry name" value="PAF_acetylhydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="460"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR018169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR018169-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK85277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="615" mass="68416" checksum="540DAF09FCA2CDCF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSG0</accession>
    <name>X0CSG0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_10539</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSG0"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="72"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK85452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="427" mass="48439" checksum="3424CB2F61EC9293" modified="2014-05-14" version="1">MVSANLLRAARIRISVPSIAVAFFPTYVRQYHGGQTPAQEYRCDVDAEPMHRCRPGGYHPVALGDSLSDGRYKVLHKLGWGSYSTTWAAKDQTHDRYVALKITVAEARRSRDTEIFQSLAASPRNHEGSCYVNQMWDQFTLIGPNGSHDCLVLDLVGPNIADIIDSHCRGDRLPSHAAKSISRQVLQGIDYLASNGIGHGDLHTRNIALEIPELHLLSERDFITRLGEPEMGLVTRRDGKSLPSNIPTCIVRPSSFRHKDVQRLLSSPSIKTIDFGEAFFNYDALNTLHTPLPVRAPEIVFGDRLDNRVDLWSTGCLMFELVTGQPPFDVVMLTPPMLVQQMIELIDDELPSRWQVKWKEMEGEGLQQQDAWKLQSWMEEVYFHNNKHVEFTRDELRAIAKLIARLMRFEPSTRATPSELLADPWFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSP1</accession>
    <name>X0CSP1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Glutamate synthase [NADH]</fullName>
            <ecNumber evidence="19">1.4.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">FOQG_05056</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="27 28">54005</strain>
        </source>
    </reference>
    <reference evidence="27" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21">Forms L-glutamate from L-glutamine and 2-oxoglutarate. Represents an alternative pathway to L-glutamate dehydrogenase for the biosynthesis of L-glutamate. Participates with glutamine synthetase in ammonia assimilation processes. The enzyme is specific for NADH, L-glutamine and 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="24">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="24">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.14" evidence="19"/>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_8_0_1"/>
    <dbReference type="OrthoDB" id="4327079at2759"/>
    <dbReference type="UniPathway" id="UPA00045"/>
    <dbReference type="UniPathway" id="UPA00634">
        <property type="reaction ID" value="UER00690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019676">
        <property type="term" value="P:ammonia assimilation cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097054">
        <property type="term" value="P:L-glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000160">
        <property type="entry name" value="Glutamate synthase (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000006">
        <property type="entry name" value="Glutamate synthase (NADPH/NADH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000031">
        <property type="entry name" value="Glutamate synthase 1 [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000017">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000022">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.60:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="entry name" value="Glutamate synthase, alpha subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012220">
        <property type="entry name" value="Glu_synth_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008730">
        <property type="entry name" value="PRK11750.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000187">
        <property type="entry name" value="GOGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="Alpha subunit of glutamate synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18 24" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0288">FMN</keyword>
    <keyword evidence="17" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="13" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="15" id="KW-0408">Iron</keyword>
    <keyword evidence="16 24" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="26">
        <location>
            <begin position="54"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="961"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="23">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1184"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1190"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1195"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00024383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00057049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00068518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="EXK93884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="2113" mass="233587" checksum="666FD6A26AFB6619" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT42</accession>
    <name>X0CT42_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidoligase enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT42"/>
    <dbReference type="eggNOG" id="ENOG502T5XN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_655585_0_0_1"/>
    <dbReference type="OrthoDB" id="4940520at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022025">
        <property type="entry name" value="Amidoligase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847:SF1">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12224">
        <property type="entry name" value="Amidoligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="475" mass="52261" checksum="78CC39094E13684E" modified="2014-05-14" version="1">MELSAINRNPLGAPASSGCSTASLLSSLRNYHHIQVDKHFHLREKTPAIPASPEPSMPIPQSISVGIELEFMVALQIPNSDAVTGEARWACPTTPEAFLGLVMGDYKDIEPSCIHKVCELIANSGVSVSCSLIPPSPISPAQIPGTAILPLTDNSGDIRAWNNESVSGPVSKTDFWFIVPERHITRDCVSKSGMTPSNKYDWYGTELNSPILTRPEEFSQGLPTLRKCLAAVQGGMVVGLNSGCGLHLHVNDAGSMQLETALRLASLVWLLEDSLLYPLCHPFRSTSPYSARISVESRIAMERGEPTVYGEGAALVEALGEVMRQLHWRKKVDRGLLGSMKRLWSETSLASLGIALRKFDEGSLHTTTRCALVVSKYDTIEFRYPESTFDVDFIAGWADLVRHLYAVAMRPQVEFHQILCRVYELVTRDQMPGWSAMLGAIGFQGDASRWQRHINEYGDTLSNLDKQGILQNIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTM2</accession>
    <name>X0CTM2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTM2"/>
    <dbReference type="eggNOG" id="ENOG502T876">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1046000_0_0_1"/>
    <dbReference type="OrthoDB" id="2896390at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="262" mass="29277" checksum="58335C6599ADAB42" modified="2014-05-14" version="1">MGDSRDTKAAVLSAVTDFFNISPKSPKDARNHLLETSYVIQSTPDTIEQTTLGELFLSDKKQKGHLEWAIDEPQELFIHEKLAAAWTGWSICADDGTIISHKKGILGLAYTDGRWKISGLASTERSLETPDPEDESTLTQEIMKPINALLDDFSHPDWDVLKQWFLPNAGVTLYRPPAEPAPMTMEQSIVRLQGMIKSGITIQEKLHDIQVRKHGDIALVWAPFVVEINGVPKHDGVNAFTLLRREGRWVFSGCQDYGVALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU47</accession>
    <name>X0CU47_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">DNA replication ATP-dependent helicase/nuclease</fullName>
            <ecNumber evidence="22">3.1.-.-</ecNumber>
            <ecNumber evidence="22">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="29" type="ORF">FOQG_04488</name>
    </gene>
    <organism evidence="29 30">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="29 30" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="29 30">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="22">Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21 22">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="22">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="22">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 22">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="22"/>
    <dbReference type="EC" id="3.6.4.12" evidence="22"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1805">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001666_2_1_1"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071932">
        <property type="term" value="P:replication fork reversal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18041">
        <property type="entry name" value="DEXXQc_DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22318">
        <property type="entry name" value="DNA2_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000789">
        <property type="entry name" value="DNA replication ATP-dependent helicase/nuclease DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001170">
        <property type="entry name" value="DNA replication helicase Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.320.10:FF:000001">
        <property type="entry name" value="DNA replication helicase Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022765">
        <property type="entry name" value="Dna2/Cas4_DUF83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026851">
        <property type="entry name" value="Dna2/JHS1_DEXXQ-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048459">
        <property type="entry name" value="DNA2_Rift"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014808">
        <property type="entry name" value="DNA_replication_fac_Dna2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF433">
        <property type="entry name" value="DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01930">
        <property type="entry name" value="Cas_Cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08696">
        <property type="entry name" value="Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21123">
        <property type="entry name" value="Dna2_Rift"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 22" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="22" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 22" id="KW-0227">DNA damage</keyword>
    <keyword evidence="18 22" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 22" id="KW-0235">DNA replication</keyword>
    <keyword evidence="16 22" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="12 22 29" id="KW-0347">Helicase</keyword>
    <keyword evidence="11 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14 22" id="KW-0408">Iron</keyword>
    <keyword evidence="15 22" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 22" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="20 22" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 22" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19 22" id="KW-0539">Nucleus</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Dna2 N-terminal" evidence="25">
        <location>
            <begin position="507"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="DUF83" evidence="24">
        <location>
            <begin position="721"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2 rift barrel" evidence="28">
        <location>
            <begin position="881"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="26">
        <location>
            <begin position="1074"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="26">
        <location>
            <begin position="1177"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="27">
        <location>
            <begin position="1250"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="269"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1525"/>
            <end position="1552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="297"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="23">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="23">
        <location>
            <begin position="1532"/>
            <end position="1549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU367041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF08696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF21123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="EXK94399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1578" mass="177053" checksum="A83AB0EBC3B49990" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUG6</accession>
    <name>X0CUG6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUG6"/>
    <dbReference type="HOGENOM" id="CLU_1562932_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="171" mass="19323" checksum="3BF7CAFDF40FE6CA" modified="2014-05-14" version="1">MRVLACQSSVSVQRIRKNGIKDIVARRLCGNLRVAPLCLLWSQRDEGNPVQHHPAYSRTRAMVNCGHTHMLAFETLSCQPPIIANMSPWRAHQGCSEERLVFQPRHAARLPQCHGQGKRGKLGEPLPRGQVITSTTTHQFKVLWASETGHHVKRPTNETWKNELLSSAREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CW36</accession>
    <name>X0CW36_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CW36"/>
    <dbReference type="eggNOG" id="ENOG502S8NV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129819_0_1_1"/>
    <dbReference type="OrthoDB" id="2147008at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009732">
        <property type="entry name" value="DUF1304"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38446">
        <property type="entry name" value="BLL0914 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38446:SF1">
        <property type="entry name" value="BLL0914 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06993">
        <property type="entry name" value="DUF1304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="121" mass="13029" checksum="B616125C9EBC8466" modified="2014-05-14" version="1">MGAIGLTASGLVGALHSYILVLEMFLWTKPRGRKAFRLTPEFAEQTKTMAANQGLYNGFLSAGLIWSLLHPNPEFSKQLQIFFNGCVLVAGAYGGLTANKKILYIQAAPAALSLGLVLLDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWE0</accession>
    <name>X0CWE0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Signal recognition particle 54 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_04168</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes. SRP54 interacts with the scR1 RNA and mediates the association of the resulting SRP-RNC complex with the signal recognition particle receptor (SR) via its alpha subunit SRP101. Both, SRP54 and SRP101, are locked in their GTP bound forms in the SRP-RNC-SR complex, which dissociates upon transferring the signal sequence to the protein-conducting channel (translocon). After signal sequence transfer, SRP54 and SRP101 act as reciprocal GTPase-activating proteins (GAPs), thereby resolving their association.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Fungal signal recognition particle consists of a 7S RNA molecule (scR1) and at least six protein subunits: srp72, srp68, srp54, sec65, srp21 and srp14.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The M domain binds the 7SL RNA and the signal sequence of presecretory proteins.</text>
    </comment>
    <comment type="domain">
        <text evidence="13">The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit srp101. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWE0"/>
    <dbReference type="eggNOG" id="KOG0780">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009301_6_1_1"/>
    <dbReference type="OrthoDB" id="10250817at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006616">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17875">
        <property type="entry name" value="SRP54_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.30:FF:000003">
        <property type="entry name" value="Signal recognition particle 54 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000022">
        <property type="entry name" value="Signal recognition particle 54 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.140:FF:000001">
        <property type="entry name" value="Signal recognition particle GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006325">
        <property type="entry name" value="SRP54_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01425">
        <property type="entry name" value="SRP54_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="14">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK95618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="521" mass="56413" checksum="BF8645031E92DB08" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWX9</accession>
    <name>X0CWX9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWX9"/>
    <dbReference type="HOGENOM" id="CLU_093913_0_0_1"/>
    <dbReference type="OrthoDB" id="5124663at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="244" mass="27970" checksum="C9DA1A784B9A77FA" modified="2014-05-14" version="1">MTTTQVLPGIKLLRSIPSPNYRLYSSTTQILRQHTKDHPQGNPNRPRQSPNRNGTKGRPKPLRIFIPPSNDHVLPSGKLLTTPEVWSFLQETGIEYDNSKARRLHLGPDEQKVKALFNCLIQYSPRYILHPFHLQHLRPGIAPMLPVIMSNYRRKLEEEPLWTYTICRGGSSNVVRHLMVKRLTGAFWTAMKDLGYSMNGPRGTLIVTIHDPLKVAQAPAHIFGEAVAKQLKQTWEKYRLEKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXS1</accession>
    <name>X0CXS1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_09090</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_27_5_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000055">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000066">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002145">
        <property type="entry name" value="ABC transporter (MsbA subfamily)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="470"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="828"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="869"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="940"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="965"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1052"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="261"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="563"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="831"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1142"/>
            <end position="1373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK87247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1373" mass="151598" checksum="87A57F2A30C56FBA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY73</accession>
    <name>X0CY73_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01998</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY73"/>
    <dbReference type="HOGENOM" id="CLU_065853_1_0_1"/>
    <dbReference type="OrthoDB" id="2101473at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007396">
        <property type="entry name" value="TR_PAI2-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802">
        <property type="entry name" value="PROTEASE SYNTHASE AND SPORULATION PROTEIN PAI 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802:SF1">
        <property type="entry name" value="PROTEASE SYNTHASE AND SPORULATION PROTEIN PAI 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04299">
        <property type="entry name" value="FMN_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010372">
        <property type="entry name" value="PaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="253" mass="28376" checksum="94EC8C0A4A402E2D" modified="2014-05-14" version="1">MILSSAHVETRIPVLRRLIRDNALGVLTTAIPSDKHPHIQVSHIPFILDVQDEGSDTELGVLRGHIARQNPQSQAMIETLENSGSNVLDQEVLVLFTATSHHYVTPKFYTETKPTTAKVVPTWNYAAVQAYGRATVHYDSKSETSSKFLQKQLEDLSEHTETSIMNYTGKGDRPGPWKVSDAPERYIELMKKNIIGIEISIHRLDGKFKMSQEMRKGDRDGVIQGFGSMESDACQVIATMVQERSDLKEAQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYE3</accession>
    <name>X0CYE3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYE3"/>
    <dbReference type="eggNOG" id="KOG0867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_14_0_1"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10291">
        <property type="entry name" value="GST_C_YfcG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="20"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="112"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="267" mass="30748" checksum="C2D18A19E70F5A31" modified="2014-05-14" version="1">MTSRITQLGKQLFTMAQKTKTDITLYTTNTPNGIKPSILLEELNLEYKVYPIKMTENEQKEEWFLKINPNGRIPALTDTLDGKQIRVFESGAMLQYLVDRYDKDHKLSFPHGSAEHWEMTSWLMWQMGGLGPMQGQANHFKRYAPEKIEYGINRYTNETRRLYRTLDTHLAQTSSGYIVGDKVTIADISIWGWVSSAKWAGVDLSEFPHLEKWLYKLLERPGFEAGRHVPTRHTAFELAKLSEEELEAKASASKAWVQSGMKEDAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZU8</accession>
    <name>X0CZU8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_00378</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZU8"/>
    <dbReference type="eggNOG" id="KOG0293">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="972532at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051350">
        <property type="entry name" value="WD_repeat-ST_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838">
        <property type="entry name" value="WD REPEAT PROTEIN 26-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23627">
        <property type="entry name" value="LisH_WDR26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CTLH" evidence="5">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="278"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="320"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="505"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="532"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXL00056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="589" mass="64926" checksum="C3C8359605475248" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1H3</accession>
    <name>X0D1H3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_00707</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1H3"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_11_2_1"/>
    <dbReference type="OrthoDB" id="5141738at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000082">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF74">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="54"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXL00621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="503" mass="55229" checksum="3B499DFA5A2A06EB" modified="2014-05-14" version="1">MGGNETQLFGSDATMAVSPNVDVEKRHDSSDESGWSDTESWNPLNLSPVRKLHIVIAGFTCTFNGNFGSSMPSGALDIIAEQFSITNPVHLILLNSLYMVGYVLGPLLFGPLSEYIGRRPVLIGTYLGYIVFMLACSGAPNYAALLVFRFLGGINAAAPTTVIGGLYADILDDPSTRGNAMALYMTVTTIGPLIGPIVSGFSSPVSWRWPFWIAGMMAIAGLPLILTIPETYAPVLHNKMVKAHIKRREKENKKNKTEPTDEEPLELKPFNVRKIFLRPMKLLFTEPILTSTSVYLTLAYSVFYLMFQAYPRVFQGFYGLSPGMAGLAYIPFCVGVILSLGVFAIYTRYHDRQTAAGADWTKNHIYRRLPLACIASPCMVISLFWLGWTVWDSMSPIIPSLGGIFFGLGFQLLFMGMTNYLTDVFRSHSASALGAAAMLRSIGATTLPLAADSMYNNLGFHWAPSVLAFTALAMGVIPFVFIRYGERLARSSKTAREAFAIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4U6</accession>
    <name>X0D4U6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ATP-dependent helicase C23E6.02</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_01458</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4U6"/>
    <dbReference type="eggNOG" id="KOG1001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16449">
        <property type="entry name" value="RING-HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF16">
        <property type="entry name" value="ATP-DEPENDENT HELICASE ULS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="426"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="774"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="968"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="56"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="173"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="846"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="903"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="326"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="857"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="908"/>
            <end position="920"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK98598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1134" mass="127353" checksum="4D582618C545D9E4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0D679</accession>
    <name>X0D679_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D679"/>
    <dbReference type="eggNOG" id="ENOG502RJ7T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022607_0_0_1"/>
    <dbReference type="OrthoDB" id="5032844at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK90142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="613" mass="67977" checksum="DE7C8340D16F9B17" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6U1</accession>
    <name>X0D6U1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6U1"/>
    <dbReference type="HOGENOM" id="CLU_2096962_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="116" mass="12637" checksum="A7E56C894572CC86" modified="2014-05-14" version="1">MPILFAPSPGPSGFHFPFPRPNRPRFPPGIHHSPPILFPRTLTTVHTNLVSELAGGVFGSLISLQSWGLSIALPSESGDRLLSIQFPSQRILVGVQTAERSITIPKGERDLLVFSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8P7</accession>
    <name>X0D8P7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transporter SEO1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_00007</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8P7"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_4_2_1"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF15">
        <property type="entry name" value="TRANSPORTER SEO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK99524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="55173" checksum="1034099AED0D6D10" modified="2014-05-14" version="1">MSELHARKWYHWYSPTDTPEEKKLILKLDLLLVPYAFVLYWVKYVDQTNINNAYVSGMAEDLGFHGNELVQFQTIFVVGNVVGLLPFIYLFPRVPMHILVPSLDLGWGIFTLLQYRATSYAEIMAYRFLVSIFEASYFPGVHFVLGSWYRSDEIGRRGGLFYIGLTLGTMTAGLLQGAATQYLDGHNGLAGWRWNFIINAIITLPLAFVGYFLWPGTPDKPNRLVMKKSEIALAKERLERNGSKVRSTPFSWTLLRRIFTSWQFYILVFWDILFFNTSANTAAFLLWIKSLDRYNTTKVNQLGSISPALGIFFVLFINFSADLWIGRPAAITLASAINFTGLVILAVWNVPEAAKWYAYSVGYSAVAVSSVLYGWANTILRHNNEERALTLILMTAIATSTQAWIPLLVYPTVEAPRFPKGYVYSAVMVVLLVAMTQVIRIVYGSHGEKVRARRGSLSDESEDGEIQAPHGLRIDKDAGKHIQPSTVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0DAT9</accession>
    <name>X0DAT9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 5A</fullName>
            <shortName evidence="8">eIF-5A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_06366</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the eIF-5A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DAT9"/>
    <dbReference type="eggNOG" id="KOG3271">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102600_1_0_1"/>
    <dbReference type="OrthoDB" id="9975114at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006452">
        <property type="term" value="P:translational frameshifting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04468">
        <property type="entry name" value="S1_eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000007">
        <property type="entry name" value="Eukaryotic translation initiation factor 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000034">
        <property type="entry name" value="Eukaryotic translation initiation factor 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020189">
        <property type="entry name" value="IF5A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019769">
        <property type="entry name" value="Trans_elong_IF5A_hypusine_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00037">
        <property type="entry name" value="eIF_5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01287">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003025">
        <property type="entry name" value="eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01376">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00302">
        <property type="entry name" value="IF5A_HYPUSINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0385">Hypusine</keyword>
    <keyword evidence="10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Translation initiation factor 5A C-terminal" evidence="9">
        <location>
            <begin position="89"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK91672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="164" mass="18024" checksum="5B2E429CE4E8D746" modified="2014-05-14" version="1">MAAPNDAEHEMTFDSADAGASLTYPMQCSALRKNGFVVIKNRPCKIVDMSTSKTGKHGHAKVHLVATDIFTGKKYEDLSPSTHNMDVPNVSRREYQLLDISDDGFLSLMTDDGDTKDDVPLPDNEVGQKITKLFKEEEKDTNVIVLTSMGEECAMEAKEAPNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCP5</accession>
    <name>X0DCP5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Required for respiratory growth protein 7, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCP5"/>
    <dbReference type="eggNOG" id="ENOG502S6ZS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060368_1_1_1"/>
    <dbReference type="OrthoDB" id="20734at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018828">
        <property type="entry name" value="RRG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133:SF1">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10356">
        <property type="entry name" value="RRG7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="28704" checksum="309AC213CF4F30C7" modified="2014-05-14" version="1">MMPILLRGFFNVSRHVNQSTKWCRAINGAKLMSKRKAEAPKPFELIYPDAPTKEHSDLKSFLSYVERVSLNKRSTVYRGTHYEYTVADTLSQYGFFLKRVGGQSDRGMDLLGIWTLPSTTQTFKVILQCKAGARSASPMYVRELKGAMAAAPPGWRGNDVLGLLVGEKPATKGVQGEMHSADVALGYVCCSKEGDVLQLLWNIKAQAMGLDGVTVGLKYGEDNNKLVLLRGGEMLPLLEKAETEGEDVVVDVSAIEIEGSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0DDB8</accession>
    <name>X0DDB8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ubiquitin-activating enzyme E1 1</fullName>
            <ecNumber evidence="4">6.2.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_05647</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.45" evidence="4"/>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DDB8"/>
    <dbReference type="eggNOG" id="KOG2012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10252231at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004839">
        <property type="term" value="F:ubiquitin activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01491">
        <property type="entry name" value="Ube1_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01490">
        <property type="entry name" value="Ube1_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2660:FF:000001">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12550:FF:000001">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000015">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.180:FF:000001">
        <property type="entry name" value="ubiquitin-like modifier-activating enzyme 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.60:FF:000002">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.80:FF:000001">
        <property type="entry name" value="ubiquitin-like modifier-activating enzyme 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.180">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, FCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.80">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12550">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2660">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, SCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.60">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, UFD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032420">
        <property type="entry name" value="E1_4HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032418">
        <property type="entry name" value="E1_FCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042302">
        <property type="entry name" value="E1_FCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018965">
        <property type="entry name" value="Ub-activating_enz_E1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042449">
        <property type="entry name" value="Ub-E1_IAD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038252">
        <property type="entry name" value="UBA_E1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042063">
        <property type="entry name" value="Ubi_acti_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018075">
        <property type="entry name" value="UBQ-activ_enz_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01408">
        <property type="entry name" value="Ube1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF4">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16191">
        <property type="entry name" value="E1_4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16190">
        <property type="entry name" value="E1_FCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09358">
        <property type="entry name" value="E1_UFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00985">
        <property type="entry name" value="UBA_e1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-activating enzyme E1 C-terminal" evidence="12">
        <location>
            <begin position="901"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00073786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK92537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1034" mass="115506" checksum="09A72989EAC9F2D0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0DEZ8</accession>
    <name>X0DEZ8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_05298</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000799_1_1_1"/>
    <dbReference type="OrthoDB" id="7326421at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000577">
        <property type="entry name" value="WD domain G-beta repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034605">
        <property type="entry name" value="PGC-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15528:SF11">
        <property type="entry name" value="FI18188P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15528">
        <property type="entry name" value="PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="356"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="413"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="497"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="634"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="722"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1147"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="371"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="515"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="634"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="774"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="795"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="832"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="845"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="923"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="957"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1046"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1101"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1168"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1234"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1251"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1280"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1330"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1344"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1402"/>
            <end position="1412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK93087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1412" mass="154111" checksum="FA333BE4EC0B8F23" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0DRY9</accession>
    <name>X0DRY9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mediator of RNA polymerase II transcription subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Mediator complex subunit 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MED9</name>
        <name evidence="9" type="ORF">FOQG_02379</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Mediator complex subunit 9 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DRY9"/>
    <dbReference type="eggNOG" id="ENOG502SW8C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097220_2_0_1"/>
    <dbReference type="OrthoDB" id="5414694at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011425">
        <property type="entry name" value="Med9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07544">
        <property type="entry name" value="Med9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0010">Activator</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="49"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK97037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="148" mass="15792" checksum="582DBA4B48123B54" modified="2014-05-14" version="1">MSPSSASAPASASGPHPLALPPTFSPDTLDALSELSLVLARVRAGIQSSAGITTEPAPGTTGHNASGPTLSFKDVPGATDGLKHKLQRARAQVRELPDMDRSIAEQNDEIRDLENRIEKQRALLQRLRDEATGRDRKEEVSAGDKMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0DTH1</accession>
    <name>X0DTH1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RAD50-interacting protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DTH1"/>
    <dbReference type="eggNOG" id="KOG2218">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015529_1_0_1"/>
    <dbReference type="OrthoDB" id="2189254at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070939">
        <property type="term" value="C:Dsl1/NZR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060628">
        <property type="term" value="P:regulation of ER to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007528">
        <property type="entry name" value="RINT1_Tip20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520:SF0">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1 RINT-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04437">
        <property type="entry name" value="RINT1_TIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51386">
        <property type="entry name" value="RINT1_TIP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="813" mass="92523" checksum="2FDC6BD5C348269F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0DWF9</accession>
    <name>X0DWF9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DWF9"/>
    <dbReference type="eggNOG" id="ENOG502T65R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132180_0_0_1"/>
    <dbReference type="OrthoDB" id="5131008at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="140" mass="16055" checksum="3D92D97C6FC685E4" modified="2014-05-14" version="1">MEAWPVTDLDKIAKGWKIAMKCSKERLQRVHDLAADELDDAINDGHLVLETVCLFVHACIKHNQYKLPLSFWRVLHAEYGIIVYPTAFTEDIDIQGLNIDVTFTEAYNGHIMMYGGARGIKYPPRCPLELIREPPPVYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0E079</accession>
    <name>X0E079_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Multifunctional methyltransferase subunit trm112</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eRF1 methyltransferase subunit trm112</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00166</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRM112 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E079"/>
    <dbReference type="eggNOG" id="KOG1088">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086140_0_0_1"/>
    <dbReference type="OrthoDB" id="2187549at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000021">
        <property type="entry name" value="Multifunctional methyltransferase subunit trm112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039127">
        <property type="entry name" value="Trm112"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773:SF0">
        <property type="entry name" value="MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773">
        <property type="entry name" value="UPF0315 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00069342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00083044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK99742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="127" mass="14066" checksum="C988FB5E78969A82" modified="2014-05-14" version="1">MKVLSLNFLTCAVKACKSSKDSYPLHPKDAELVQDDIELNPDMILNVLPRLDWTALCTTASELGFPQLPEQPPTAVELRADEKTLKDLHHLLLETQMSEGKLVCGNCGHEYAVKEGIANFLLPSHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0E1S0</accession>
    <name>X0E1S0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E1S0"/>
    <dbReference type="HOGENOM" id="CLU_3032417_0_0_1"/>
    <dbReference type="OrthoDB" id="5005310at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="55" mass="6070" checksum="317309B12E71C6A3" modified="2014-05-14" version="1">MEDLRVHFEGDQMEGAGQDSAENHSPQTKVAEGKGIDVKMTDAEVDEARYMSQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0B0C5</accession>
    <name>X0B0C5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980081">
        <property type="protein sequence ID" value="EXK75580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B0C5"/>
    <dbReference type="HOGENOM" id="CLU_2941848_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="60" mass="6949" checksum="343EFC2D76051795" modified="2014-05-14" version="1">MSSSIEEGGSGPQYMVTLWFPVTILNIQQPFKVAYYYTAFHGQFHGPRRRFAIPYSLFTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B0Z9</accession>
    <name>X0B0Z9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979819">
        <property type="protein sequence ID" value="EXK75780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B0Z9"/>
    <dbReference type="HOGENOM" id="CLU_044860_0_0_1"/>
    <dbReference type="OrthoDB" id="3485856at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="404" mass="45461" checksum="85FE35AFE7480F6D" modified="2014-05-14" version="1">MEDTHPTSPDSSPKRFSHPPKSHRKITPPERKSLPSPPASGERNRASTADELPQSLVEFKRKVETAGDVSPLTSFHLSKADFTRLHAKLEAHFRRFDYEPRHQRIIFRMPSRTHDHFAQFIYDDIFNAISEHARDSEQVRSFSANIKKAGTADIILYDSDDKSKDPVPLKRSPDAQFLYVDTAFPSVVVEVAYSQDGKQLSKIAKQYIHYSDGNIKAVLCFDLNKGSESTISVWKPRFIPEQDSDEFKMEIEQVVQSQPFRTADGSPINQDHALVLDLHDFALDELCEGYPNPSISIPYSKLYDSLVMAERLAKSVTTGMRSKRGVKRGRLSTSSVESMTSEDKKKWKDNDHAVKKKQNAEDGEYEGVDDGASPAKKRAQLARQCTRPSVLDSDSDSDGTGVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0B270</accession>
    <name>X0B270_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658753">
        <property type="protein sequence ID" value="EXK76180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B270"/>
    <dbReference type="HOGENOM" id="CLU_017783_1_0_1"/>
    <dbReference type="OrthoDB" id="2142759at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="2">
        <location>
            <begin position="236"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="527" mass="58553" checksum="DDB49ABBA63545F2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-09-13" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2J5</accession>
    <name>X0B2J5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier protein] reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979533">
        <property type="protein sequence ID" value="EXK76335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2J5"/>
    <dbReference type="HOGENOM" id="CLU_2638180_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8145" checksum="06C9D7BD757F31E4" modified="2014-05-14" version="1">MPMLNMSRPLQSLLSTFAGNANGPVTEDITQATEAAITIGRIVDPFDVADAVLFLADPARSLLSGAEIRDDGDRSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2S9</accession>
    <name>X0B2S9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979511">
        <property type="protein sequence ID" value="EXK76430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2S9"/>
    <dbReference type="HOGENOM" id="CLU_025948_0_0_1"/>
    <dbReference type="OrthoDB" id="4129906at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008782">
        <property type="term" value="F:adenosylhomocysteine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008930">
        <property type="term" value="F:methylthioadenosine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46832">
        <property type="entry name" value="5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46832:SF1">
        <property type="entry name" value="5'-METHYLTHIOADENOSINE_S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="346" mass="37828" checksum="8BB83E0A01CBD793" modified="2014-05-14" version="1">MPYYVTSSSRQGIQTFGVEAATLFSVLKPRYALHVGVCAAISGQNIAVEDVIFGERALNYEEGKWALKDDQVVFKPDVKVAEVKDAAMGGFIAQADQPLYKYGDFVSGCAIHMDASFIFDRVKNTTLRNVAALDMEASAFLQACEFTGVRSLGVIKGVSDMGDGNRGLGPNDKHYKSALLRAARAVKRFVSYRWEDMPPKEAMDRSKQPGAVITRGYFDNFVARVMDKLSKTGYKASTEIKVEGLKVVLPKGNKAVSFDANRGALTHHIQAHGLQDVILPGPPKPTPAHLKGSYLVDLPTTLAGTLENEPGSEAQVELFGKVLAERVEEAYEGFVEVITWEKFTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5A1</accession>
    <name>X0B5A1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MUC1 Extracellular alpha-1,4-glucan glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658662">
        <property type="protein sequence ID" value="EXK76941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5A1"/>
    <dbReference type="HOGENOM" id="CLU_019363_1_0_1"/>
    <dbReference type="OrthoDB" id="2890403at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936142" description="MUC1 Extracellular alpha-1,4-glucan glucosidase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="555"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="681" mass="70391" checksum="FE739498A4C89B75" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0B727</accession>
    <name>X0B727_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17723</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658592">
        <property type="protein sequence ID" value="EXK77576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B727"/>
    <dbReference type="HOGENOM" id="CLU_107716_0_0_1"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01443">
        <property type="entry name" value="Cdc25_Acr2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF50">
        <property type="entry name" value="REDUCTASE (ARC2), PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13400)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="41"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="154" mass="17247" checksum="37DADCC5A7E34829" modified="2014-05-14" version="1">MTSTDAATPWHAAYPPPLNKTPAAMTRQEVLEMMKDSKNIAGRNYVLIDLRRTDHEGGNIRGSINLPAQSLYPTIKTLYGLFKSAGVQKIIWYCSSSRGRGSRAAGWFKDHLDEQGDSHMESMILFEGITGWAKAGGEFVEWMDEYDATVWDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7P4</accession>
    <name>X0B7P4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658574">
        <property type="protein sequence ID" value="EXK77776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7P4"/>
    <dbReference type="HOGENOM" id="CLU_141747_0_0_1"/>
    <dbReference type="OrthoDB" id="5020773at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="157" mass="18271" checksum="E308D88BBE4FF4DF" modified="2014-05-14" version="1">MQEVRSLNSDQRRDLIEVGSPQIKACITVSPVGNLSVRRGFSLYLLVVHYGLKAVLYKSDPEKNLRMVHSIEMGWFILDKYYAFIESTPVYAAAMLLDPSKRKYYLLQNWPEEWRQRLSILLIRSGRRNTRFSLMNHSLPLLLLLISIRAIHPRGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB40</accession>
    <name>X0BB40_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658489">
        <property type="protein sequence ID" value="EXK78996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB40"/>
    <dbReference type="HOGENOM" id="CLU_2250290_0_0_1"/>
    <dbReference type="OrthoDB" id="5107616at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="104" mass="11893" checksum="A7F5BD224E92A5F4" modified="2014-05-14" version="1">MQLNDFKYTGCLLAFALITYAIEYTCRKLLFFFRLALVFASFAVMTKQRPATQQIKRWLETAGIEEIPRMALFKDIQKAATTGLQAVTMLFERGGAQDTSIKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBS7</accession>
    <name>X0BBS7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979684">
        <property type="protein sequence ID" value="EXK75964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBS7"/>
    <dbReference type="HOGENOM" id="CLU_3359756_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="36" mass="4185" checksum="E49416A86FAECA1F" modified="2014-05-14" version="1">MLFSGLKPWTATVRRSMMNCISTASILVRTHMEMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBV2</accession>
    <name>X0BBV2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucans biosynthesis glucosyltransferase H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_18961</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; osmoregulated periplasmic glucan (OPG) biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 2 family. OpgH subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979549">
        <property type="protein sequence ID" value="EXK76293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBV2"/>
    <dbReference type="HOGENOM" id="CLU_015730_1_2_1"/>
    <dbReference type="OrthoDB" id="3717264at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050321">
        <property type="entry name" value="Glycosyltr_2/OpgH_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003962">
        <property type="entry name" value="PRK05454.2-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867:SF5">
        <property type="entry name" value="GLUCANS BIOSYNTHESIS GLUCOSYLTRANSFERASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="446"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="500"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="13">
        <location>
            <begin position="205"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK76293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="595" mass="67573" checksum="B36181A20BCB6B8D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD08</accession>
    <name>X0BD08_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658692">
        <property type="protein sequence ID" value="EXK76683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD08"/>
    <dbReference type="HOGENOM" id="CLU_041953_0_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="165" mass="18535" checksum="C7CDB509C3E963ED" modified="2014-05-14" version="1">MDEFAQQFKAQQIEHMPLKEPMKDEDSSMWNRTERASPSKLYHSNIEHDYQEAAFSYINTIALSPQNSISSAGLNFLSLPPVVDSSTLLPSPAMSNFAAWPMAKPQPTDLDLTFQQRNGMMANMNFLNQGHVEFEVDIIKPDDLLHTSPEALGMDDSMLYSGYTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEI8</accession>
    <name>X0BEI8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658628">
        <property type="protein sequence ID" value="EXK77243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEI8"/>
    <dbReference type="eggNOG" id="ENOG502SCX2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162806_0_0_1"/>
    <dbReference type="OrthoDB" id="2559882at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="101" mass="10901" checksum="A66352BB290BC61D" modified="2014-05-14" version="1">MSDLNTQTTVQNGRGHGPPHTTGHSKAQEKAPQGLEEHLPDSVHRTGPEPGQFTHKTHAKDGGKASIVPQKLQEKLPESIERAVPNAIHNTDDAGGLHRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF03</accession>
    <name>X0BF03_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658646">
        <property type="protein sequence ID" value="EXK77064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF03"/>
    <dbReference type="HOGENOM" id="CLU_002467_1_0_1"/>
    <dbReference type="OrthoDB" id="5369347at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="610"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="672" mass="78514" checksum="816709D7C2812DD7" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF09</accession>
    <name>X0BF09_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658645">
        <property type="protein sequence ID" value="EXK77069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF09"/>
    <dbReference type="HOGENOM" id="CLU_2527561_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="84" mass="9191" checksum="3C55A6300E178ECB" modified="2014-05-14" version="1">MSGQAFLPQVDSGVLEPGVSIAKLIYWDAGVEQGCLQKAIGLNFKAGNLHGQTTKLIRETKPAKTPTPGLPTRRERLLYLSRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFS2</accession>
    <name>X0BFS2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK81015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFS2"/>
    <dbReference type="eggNOG" id="ENOG502RVZ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_576227_0_0_1"/>
    <dbReference type="OrthoDB" id="5023749at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935697" evidence="1">
        <location>
            <begin position="19"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="475" mass="52647" checksum="3E27C3F6EE8FEC69" modified="2014-05-14" version="1">MMKLQLLLFALFASLAQAQWKGCSSPWPNITPGKEFTLKDKCRTLAGYPKKFEEANTEVTVTYTQQWSRLPSKTKTAVNPILKESLEKSMEVYRKFAKLPSSIIIILTTESDEDFTAETVYPNLRKPPCQIKLFNRWTTEATTNKPRVLQALAHEIYHCIQDLGKLGNSVDPQWVRDGSANYFSNLVFPDSNAEWPDKKHSGVAYKPNLPIYAHVGKEAYATSIFFQAQRKMDEDAINKFVLATPGGSTGLQERARLSDLSGFADEFFTFAKDFALQQIKDTNGDLIPIDKINPVSASIKFDKAGTTGTATLTSTPFTISVFKITIDPGRTAKIYSSANDNQKLAYRKSDAKSWTDMATDSSSGRTIDLPCNQKNTKQTYIIVFISTQDVKSDKVKITVATSKPKKCGARSGFVLYPLFNPTTSGGYCPKGTHSSRLAIWCCPDGTQLDEHVAQQVSICCPTGQSRVVNVVTLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFU1</accession>
    <name>X0BFU1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_17942</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658618">
        <property type="protein sequence ID" value="EXK77349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFU1"/>
    <dbReference type="HOGENOM" id="CLU_000288_34_14_1"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031352">
        <property type="entry name" value="SesA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17107">
        <property type="entry name" value="SesA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT-NTPase and P-loop NTPases N-terminal" evidence="4">
        <location>
            <begin position="10"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="5">
        <location>
            <begin position="241"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="746"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="853"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="879"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="881"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK77349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="912" mass="102906" checksum="B3642B699D1301B0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFV9</accession>
    <name>X0BFV9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658615">
        <property type="protein sequence ID" value="EXK77369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFV9"/>
    <dbReference type="HOGENOM" id="CLU_021591_0_0_1"/>
    <dbReference type="OrthoDB" id="5077295at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="102"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="328"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="422"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="506"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="717" mass="82165" checksum="45B9095B4D67EDE1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGM2</accession>
    <name>X0BGM2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1446 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979334">
        <property type="protein sequence ID" value="EXK81285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGM2"/>
    <dbReference type="eggNOG" id="ENOG502QS8D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012617_0_0_1"/>
    <dbReference type="OrthoDB" id="10265871at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056362">
        <property type="entry name" value="AtuA-like_ferredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585:SF1">
        <property type="entry name" value="DUF1446 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23544">
        <property type="entry name" value="AtuA_ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="1">
        <location>
            <begin position="7"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="AtuA-like ferredoxin-fold" evidence="2">
        <location>
            <begin position="493"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="607" mass="67244" checksum="6ADFE90B9FA86243" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIH2</accession>
    <name>X0BIH2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1989 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK81975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIH2"/>
    <dbReference type="eggNOG" id="ENOG502R5K1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079904_1_2_1"/>
    <dbReference type="OrthoDB" id="504708at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018959">
        <property type="entry name" value="DUF1989"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31527">
        <property type="entry name" value="RE64534P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31527:SF0">
        <property type="entry name" value="RE64534P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09347">
        <property type="entry name" value="DUF1989"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1989" evidence="1">
        <location>
            <begin position="14"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="202" mass="22136" checksum="7740E14AB256ED87" modified="2014-05-14" version="1">MEDTRQLSDGIIELAPRTGTSFVVNKGQRLTVIDPKGGQVSDLVAFNQHDTDEVISNGRTFDYADTIYLTTNHPLYSNRSNVMLKIVDDTCGRHDFLLTPCSKDTFRIIYGDKEPHHGCFGNLSLALSKYGIAPDRIPCAFNCFMNVPVDGKTGKFTVEPPISKAGDHIDFVAEMDLIVAITACSAGKSNGGSFKPIQYKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK04</accession>
    <name>X0BK04_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_13211</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK04"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF70">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="368"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="72"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK82500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="519" mass="58589" checksum="2A354FC21BE5D457" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BL20</accession>
    <name>X0BL20_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979345">
        <property type="protein sequence ID" value="EXK79593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BL20"/>
    <dbReference type="eggNOG" id="ENOG502T0CM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1115788_0_0_1"/>
    <dbReference type="OrthoDB" id="4820872at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="249" mass="28059" checksum="65E2C67C719ABA7C" modified="2014-05-14" version="1">MSQTSLVESSSSGEAPRNALSLRLEAPLFSQVSISPTKQSFNIQGRYVYETEASPATPTYHISNRNTQAGNPWQLQICRLLPSEVRRLGEATGNDAFIRYDDDLTLYSGEKMNIPFSFAAGLGPTPLIVIRGQKRGTIQGSIVMEKSGRSCKFYHMIPIKRALTKAEEDRMQALMHKRGYRDSDDWKKKLLLTVQENSIKVTEWIDEYESIVAVEKDDKLEFSGEIQAEKKDLVVACWACKGFVLDKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLE5</accession>
    <name>X0BLE5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7703 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_15753</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658464">
        <property type="protein sequence ID" value="EXK79693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLE5"/>
    <dbReference type="HOGENOM" id="CLU_045148_4_0_1"/>
    <dbReference type="OrthoDB" id="405906at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056120">
        <property type="entry name" value="DUF7703"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24802">
        <property type="entry name" value="DUF7703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7703" evidence="3">
        <location>
            <begin position="20"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK79693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="280" mass="31375" checksum="2EE4C3D926FD7879" modified="2014-05-14" version="1">MMIPRSNSPQAREAHLTGPNAFVIACFLAIAMYNFIELNYCILITFQRWGGLYFWSFVAATWGILPYTIGFILKNFRPETNPYIYVTLIVVGWWPMVTGQSLVLYSRLHLVLRHPRILRAVLIAIYVDAVICYVPTTILVYGSNSSNPGPFVNPYSVWEKVQVTIFFLQELVISGLYILATIKFLRVTAITRRDGHGDVMRHLIGVSILIVILDITILAFEYANLYSLQTSYKALAYSVKLKLEFSILNRLVAVMQGRRGSSSTGAARASSSTGVPSSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNG1</accession>
    <name>X0BNG1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658444">
        <property type="protein sequence ID" value="EXK80453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNG1"/>
    <dbReference type="HOGENOM" id="CLU_026661_1_0_1"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="54752" checksum="0146391E8CD3F07E" modified="2014-05-14" version="1">MVSSDASGASIDNDAEETEASDLPGCLATPLNADVRLQQAFEQVLHLKRQNLFNQTVPLDYHIEPEIAKACIENFCTHFQIDTFPSFINIKLMHLIPDIIDMPEVTLEPAVLVLYYSIVYHGSVLIADDLGPQYSNLTQRVYGCCLRVLPAWRERSLGTKTDLISAILLMRASFQQCDFEFSWNMYRIVYQCIKKLNLHNIDQDFSSTFMGQSPDDGTDHDRQGLWALVLVDLFFRLLHDKPAIMTANLTEWRVNLPTINIVLEQPEHMVSTLAFFVKSRLTFLLLRFFDFFAQSSDDEDCIERIEGLCAEIEDLIGEWSIRDSMDANEENASNWWTLYDLTLMASCSMMVMSRKMEALHSEVSRLPFPCYNKPVSVLSVNIARKVLELALLGLEKYTSPLSAAYLFGAFHCHVPYGCLVNHLFVSDPGEPGSTSLSDMLLLEKVAKSMCTIAERDGDLLPLARTLHQLNIAIHATWKGKEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNY4</accession>
    <name>X0BNY4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyrroline-5-carboxylate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11847</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNY4"/>
    <dbReference type="eggNOG" id="KOG3124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042344_1_1_1"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF27">
        <property type="entry name" value="HYPOTHETICAL PYRROLINE-5-CARBOXYLATE REDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="5">
        <location>
            <begin position="9"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="6">
        <location>
            <begin position="192"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK83895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="307" mass="32284" checksum="7E9C9DA1C364408E" modified="2014-05-14" version="1">MAGLSNATLTILGTGNITKPIVKNLLPAIKDGKTDLPFTKIIACVRSEGSESKLNGQFSEYSSILTVCRGDNVKAVQNGDVIVLGVDPADIADVLAQDGIRDALSGKLLISVAAGWTKEKLESTLYGSETTKENASGRAWVIRTLPNIACMVSEGLIAIEKSPTEPQVPAELMDLTKNLFNTIGRTTEVAPRLMNATTAVGGSTPAMWAIICDAFIDASVAVGVPRATAQTMIYQSMKGSAAMLQSGLQPGDLRDQGTSPEGCTIGGIMVLEEAGVRGHLGRALREAVTLARLMETTTHVNDTRPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP16</accession>
    <name>X0BP16_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nitrogen starvation-induced glutamine rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP16"/>
    <dbReference type="eggNOG" id="ENOG502T69Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1102815_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014">
        <property type="entry name" value="EXPRESSION LETHALITY PROTEIN HEL10, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014:SF10">
        <property type="entry name" value="RICH PROTEIN MS8, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="25630" checksum="4047E51AE4349220" modified="2014-05-14" version="1">MSAQDYYSGGGGGYGQQQQQGGGYGQQQGYGQQQQGYPQQQQYSQGSNYGSNQPSYDNRDQSYGQHQGGQYGGGPNQYPDGAGGPGGPGGPGGPDGERGLGATLAGGGAAGWAAHTAGSGLLGSLASAAAGAIGANFLEHKFKKHKKEKNRKHHRDGRPRAFTGDSTSSSDSDSGDERRRRKDDDLAYGKSQYDNSSRHGHGGGSYGGSSSYGGGGYGGRDQGYGGGQSYGGQGGYGGQGGYGQQGYGGTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPD6</accession>
    <name>X0BPD6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11779</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPD6"/>
    <dbReference type="ESTHER" id="fusof-f9g5h7">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1516">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_5_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152108" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="23"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="550" mass="60165" checksum="A8F576854BD1C6C5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ35</accession>
    <name>X0BQ35_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">4-nitrophenylphosphatase</fullName>
            <shortName evidence="5">PNPPase</shortName>
            <ecNumber evidence="3 5">3.1.3.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_11712</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21664"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57917"/>
            <dbReference type="ChEBI" id="CHEBI:61146"/>
            <dbReference type="EC" id="3.1.3.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Divalent metal ions. Mg(2+) is the most effective.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.41" evidence="3 5"/>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ35"/>
    <dbReference type="eggNOG" id="KOG2882">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043473_0_0_1"/>
    <dbReference type="OrthoDB" id="413953at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000039">
        <property type="entry name" value="Phosphoglycolate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006349">
        <property type="entry name" value="PGP_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01452">
        <property type="entry name" value="PGP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00050247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00066659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00069197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK84265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="308" mass="33986" checksum="887F4129E7903DD9" modified="2014-05-14" version="1">MASSPKYISGDAAAVSEFIDKFDVFLLDCDGVLWSGDHVYEGVPETIEYLRSKGKRTVFVTNNSTKSRDEYLKKLTNLGIPSEKDDVFGSSYSAAIYISRILKLPENKRKVFIIGEAGIEHELESEGVPHIGGTDEAFRRDITNDDFKGIADGSLLDPEVGVVLCGLDYHVNYLKYAHAMHYIKRGAIFLATNVDSTLPMHHDFFLGAGSCHIPVVHATGKQPLALGKPSQAMMDAVEGKFQLDRSRTCMVGDRLNTDIKFGIEGRLGGTLHVLTGVNKKEDWEKADAIAVPSHYADKFSDLRLAEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ75</accession>
    <name>X0BQ75_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11568</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ75"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="10"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="303"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK84310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="424" mass="47103" checksum="D278AB582E9D9464" modified="2014-05-14" version="1">MTKLVQDIQKVIIIGGGPAALLAALRLRRKNGVTPTVYEIRQNPTTLGGAIGIPANGLRLLHQLGLYDEAVDKGSLTSRLVLHSLNGCTMGEIDMSSWSKEQTGFGYLRIRRTDIMDILLKAVERESISVQYGRTLTHIEEKNNQVIATFADGKTDIADFLLGCDGIHSAVRKLYVDPDQKPEYTGISNMFSMVQLHEVYTPSGPLKDLNATLTSDGLFAVTPATPTGDILYWFFSREIPLPQSDDGRDGWEARGKAETGAFTSNLLHLLGDQPSEWMDFLHDLVEKTKVVKFYPIYKLPTGRPWFRGRCLIIGDAAHAMPPHASQGVSMALEDVFLFSKMLETCSLPPEDALAAYVAKRKARTEIMLKRAEANGSVRKQTSPWRVRANELAISGGLWLYKLVGLERMGLGQKDWTYDIETEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSK0</accession>
    <name>X0BSK0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_11086</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSK0"/>
    <dbReference type="HOGENOM" id="CLU_019101_0_1_1"/>
    <dbReference type="OrthoDB" id="2988756at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF105">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="21"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="295"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK84846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="385" mass="42092" checksum="FFA66A3EE00C2A96" modified="2014-05-14" version="1">MSDPVVEGWTLYAVGVASTILRFYARMRVDGLRSLQAEDYLMAISIVFYTIQTTLAYNIGILAHGLANNGITDAQRAALSPSDPEYDFRIIGSKIQVAGWTIYSALIWSLKLSMLYFYTRLTTGLGRPYRIRIYVGFGLVIGTFIATMIAIFAGCQPFHKYWQINPDPGNSCQAAISKPIVWVSFAANISTDIYLIAIPLPMLWGSSLKMIKKIASTIVLGAGIFVLVCATLKSVFVLVDPVNGAELAGAWGTREAFVAVMTTNLPILFPLFRVWLTPIFGSVLRSSHKTSYQYPSGFQTIGGGGRSGKSNDPSRRGPPTANPISANMSFNNSEERIVRAEAHRMDDLTDYSASKGIIVSNVVEVIHEDKKGGSSRSREGSEGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BT42</accession>
    <name>X0BT42_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PQQ enzyme repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BT42"/>
    <dbReference type="eggNOG" id="ENOG502SHMI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_756538_0_0_1"/>
    <dbReference type="OrthoDB" id="202289at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF5">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="44626" checksum="207D1F27C2AB2262" modified="2014-05-14" version="1">MEQNTLKRRGVGLTGVDKAKSFGGYTLFGPLTSDTAHLVDIDGNEVHSWKLPGRIGRHARILPNGNLAVNTLRKTELTTKDGGPFPFPFFNKYGGGVMSELDPHGKVVRQFTDDLGHHDQYHYGDGRFLYTGLEALSPEDSAKVIGGVPGSEIDGITYADTINEVDEKGNLVWQWKVSENLPRDEYPLQPHYTREHYPLINSVIPMRDGKHILASLRSVSAVIIIERSTGNTVWKLGPEVLAQQHNATELDNGNILIFDNGAFRNGESITYTRAIEVDRQTKNIVWEYRDRSQMHNFFTPFMGSAQRLANGNTLLCESAFGRLFEVTKDGYVCWEFINPHFAPYPDQATAKIFPGESNALFRAYRYSLEEIPWLKKKLAGTYREGQASGVLGSICKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BT86</accession>
    <name>X0BT86_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thiolase-like protein type 1 additional C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_13963</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658424">
        <property type="protein sequence ID" value="EXK81674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BT86"/>
    <dbReference type="OrthoDB" id="435240at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040771">
        <property type="entry name" value="TLP1_add_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF139">
        <property type="entry name" value="THIOLASE-LIKE PROTEIN TYPE 1 ADDITIONAL C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18313">
        <property type="entry name" value="TLP1_add_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase-like protein type 1 additional C-terminal" evidence="4">
        <location>
            <begin position="441"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK81674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="526" mass="57067" checksum="0435884A46ACB99C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BU80</accession>
    <name>X0BU80_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">High-affinity methionine permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_10481</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BU80"/>
    <dbReference type="HOGENOM" id="CLU_032493_0_0_1"/>
    <dbReference type="OrthoDB" id="5982228at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF353">
        <property type="entry name" value="METHIONINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="534"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="581"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="123"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK85690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="723" mass="80319" checksum="A180424202D8252B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUH8</accession>
    <name>X0BUH8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10246</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUH8"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_38_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="206"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="289" mass="31312" checksum="120AC92EBEBBC1D7" modified="2014-05-14" version="1">MSMVLRDRMFEDMTFQEWEITTRPKAQGTWNLHNASLAAKCPLDFFLLFSSLSGILGQVGQANYASANTFLDAFARYRAGMGLPCTSLDLGAMEGIGYLDENQDLLRKMKGTGWRPVDESELVEALNVALMPPSSPQEYGDAFLLGVAPTVPLGSAESSTRLSKDVRMAAYHNIGRGQSDALPANDGLRAFLSSVKKDPSILNSHESVNTLALEIGKKLASLLLTGDVDLDTSTNTADMGLDSLVAIELRGWWKLTFGFEISTLEMLSMGTLEALGKRTADGLKGLYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVU5</accession>
    <name>X0BVU5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_13054</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVU5"/>
    <dbReference type="HOGENOM" id="CLU_000960_22_3_1"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="49"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK82629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="542" mass="57592" checksum="67B518B17ED47423" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWZ8</accession>
    <name>X0BWZ8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWZ8"/>
    <dbReference type="eggNOG" id="ENOG502TFNQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_758729_0_0_1"/>
    <dbReference type="OrthoDB" id="59675at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="365" mass="41682" checksum="5E03DAD913919CBD" modified="2014-05-14" version="1">MPSFQNLPPEVTIAILKYLNPFDLLSVLQTFNKSLYSAAEVAFRPYKEWARNAQQMVALFPPRSIHSTRRLCPSYPSHIPPLDHDNVSMSEEIPRRDYESLSLELGAGPYIRCSPPDLITWMKLDGSFEWLEPLDEDMADEMLPHNGIEGDRPVAPKADVDALVKQVSDLDLVLPTGFEAFMRSDRLHQRIPSASAWYFRLSKLIKCPAAIDDDQGGYLIRFHFDQQSCAFAYLYLSKSGCHCVLVSTVDVPMCLNEDDEINGEQLDGNNEGDDIDEESIDTSELTKEYFSLAGLSFEEYLVTVYFEGLLSFQAESFEGLEDFVKHVYRSPREVEHLRETNEAIKVFLDAQKWKGVEHYRQNISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXX1</accession>
    <name>X0BXX1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ecp2 effector protein-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXX1"/>
    <dbReference type="eggNOG" id="ENOG502SU56">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098696_1_0_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029226">
        <property type="entry name" value="Ecp2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14856">
        <property type="entry name" value="Hce2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937266" description="Ecp2 effector protein-like domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Ecp2 effector protein-like" evidence="2">
        <location>
            <begin position="36"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="151" mass="15601" checksum="B6FFCD777E7514BA" modified="2014-05-14" version="1">MLVNTSILTLLMAAFAAASPITESSPTLTKRNSVNDCGDSTFENHSSGGSPQVSDCQQIARNIAGGGTWTVGAGGEHHQLVQYGTCAFGAQGAGSNMNAAHIGNQDIIDLINSSIEKFQWEGKVGAAGVMGCQSLTGLVGGVDMRWGLYHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0D4</accession>
    <name>X0C0D4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0D4"/>
    <dbReference type="eggNOG" id="ENOG502R6U9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152681_0_0_1"/>
    <dbReference type="OrthoDB" id="5100876at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937301" evidence="2">
        <location>
            <begin position="18"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="140" mass="15483" checksum="30049F557C968244" modified="2014-05-14" version="1">MKVYHILALSAPLLALAAPMPANSQLSKKAEAESFFLQTDVGWFDGGDKKRAISKKPSTKKRAPADADAESFFLQTDVGWFDGGDKKRTTIDKRTPIVKRDQTEKREPSDAEAESFFLQTDVGWFDGGDKKRATGDARSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0I0</accession>
    <name>X0C0I0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1295 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0I0"/>
    <dbReference type="eggNOG" id="KOG4650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043418_0_1_1"/>
    <dbReference type="OrthoDB" id="201504at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF23">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="356" mass="40874" checksum="508AC532870BAE2E" modified="2014-05-14" version="1">MSLPFVKSIEDCGEYAKTVQPYIPQLYALPRHILDNIASPDGLRQIYVDTNPLISGFAISIALGFVFLVVSEINRNYSQVDRMWSILPNLYVVHLSVWARLAGVPSSRVDLIAAATTLWSCRLTYNYWRKGGYNKGSEDYRWAILQQYVPRFVWFLFNVTFISFYQSALLFSFSCVPAYAILCSTKFEQDVTTADIVFALIMVGLVYSEWVSDGQQWDYHAAKHQYQAEAKVPKKFKYSQADLDRGFNTSGLWAYSRHPNFAAEQMIWFVLYQWSCFATKNIYSYTFTGAAALILLFQGSTWLTELITAGKYTEYPMYQEQVGMFLPKSLTPYKTPGPKVIRTSDIAKRMENKKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C155</accession>
    <name>X0C155_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C155"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646:SF1">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646">
        <property type="entry name" value="YALI0F00814P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="15534" checksum="5854077DED4C749A" modified="2014-05-14" version="1">MRTKTCYCPQSGRHEMKTMHLTDMYRLVEVRAAQRTFEGAYVRTALGQFSFALIILKVFTEEFYAIGALFAVYGVAVMLVAIYRRYEGQNQFFTSESADGSLKRKFRTSGNSVLLLTILSLSAYITLMVLTWRLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1V4</accession>
    <name>X0C1V4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">nitrilase</fullName>
            <ecNumber evidence="4">3.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11256</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a nitrile + 2 H2O = a carboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21724"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18379"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="EC" id="3.5.5.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.5.1" evidence="4"/>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1V4"/>
    <dbReference type="eggNOG" id="KOG0805">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_6_0_1"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000257">
        <property type="term" value="F:nitrilase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07564">
        <property type="entry name" value="nitrilases_CHs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000132">
        <property type="entry name" value="Nitrilase/CN_hydratase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044149">
        <property type="entry name" value="Nitrilases_CHs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044:SF14">
        <property type="entry name" value="ARYLACETONITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044">
        <property type="entry name" value="NITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00920">
        <property type="entry name" value="NITRIL_CHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="6">
        <location>
            <begin position="5"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00036406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK84734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="320" mass="36066" checksum="3B3B8B014DCA14DA" modified="2014-05-14" version="1">MSKSLKVAAIQAEPVWNDLQGGVNKSIGLIQEAAKNGANVIGFPEVFIPGYPWSIWANSPTENAPWINEYFKNSLERESPEMDQIRAAVREAGVFVVLGYSERYKGTLYIAQSFIDETGTIVLHRRKIKPTHVERAIYGDGQGESLTNVADTKFGKVAGLNCWEHTQTLLRYYEYSQDVDIHVSSWPSIFPQNVPEWPYHITPECCKAFSHVVSMEGACFVLLASQIMTEENHEKANVKGYDYTKKSGGGFSMIFSPFGEELVKPLDPHEEGILYADINLEEKYKAKQNLDIVGHYSRPDQLSLRVNRHAARPVFFANDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3F5</accession>
    <name>X0C3F5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3F5"/>
    <dbReference type="eggNOG" id="ENOG502SXT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070615_2_0_1"/>
    <dbReference type="OrthoDB" id="2687452at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="27114" checksum="2798BC3CD313F0CA" modified="2014-05-14" version="1">MGSNYWNNNSWYDASSPQDQASSPSGYSFDYYQSQPLVRYGSSGSNSQASTRGPESPTDGSYYTLHGSPTMDDAVYQQSPSYQQHYTSGQTRAGESSVPRGESGNDWPVSCLHPGCTARPFKRTADLIRHYKNTHAPESSKDVYLCDYPRCTRFREPFHRRDHFRDHLREYHCEDIMKRGATVNEEWLEGRYTPSTWWRCPRCLVRVNISKHGYECPGCKTSCESKRKEKRRSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3Q7</accession>
    <name>X0C3Q7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3Q7"/>
    <dbReference type="HOGENOM" id="CLU_2306289_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="100" mass="11725" checksum="2CABCFD2CDBA47CE" modified="2014-05-14" version="1">MKRNYRHSYYQTCTTSFRSPNRHILWHSIQHHDREAHLDFLGGTNPTPRDILIQAFLFFPSTSLLHLGYPPCWITWLVAKICGLERDCFYGQSPCGIKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3Y2</accession>
    <name>X0C3Y2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein BTN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_08124</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Vacuole membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the battenin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3Y2"/>
    <dbReference type="eggNOG" id="KOG3880">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029663_1_2_1"/>
    <dbReference type="OrthoDB" id="5965864at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003492">
        <property type="entry name" value="Battenin_disease_Cln3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018460">
        <property type="entry name" value="Battenin_disease_Cln3_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981:SF0">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02487">
        <property type="entry name" value="CLN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015974">
        <property type="entry name" value="CLN3_BTN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01315">
        <property type="entry name" value="BATTENIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK88841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="456" mass="49668" checksum="3FBDA15D1E020C77" modified="2014-05-14" version="1">MSGLSPSASGLLPMPGAPSSSWAVYKARAAAMMGHHDTKVIVAFWLFGLINNVLYVIILSAAQDLVGSIPKGVVLLADVVPSFLTKLIAPYFIHRIPYRMRVLIFIVLSVVGMLMVALTPRTQSVAIKLVGVVLASISAGGGELSFLGLTHFYGPMSLAGWGSGTGAAGLVGAGLYVMFTDWWGLSVRSSLLISACFPAIMFISFFVILPLGPLREGTTRKDYDAIPDLEDEDVNQMDQGTASSALLAPGPSVAATAYSAHNTQDTLTMRDRLKKVKVLFVPYMLPLLLVYVAEYTINQGVAPTLLFPLDESPFDEFRDFYPMYGFLYQLGVFISRSSTPFLRIHHLYLPSMLQVANLVLLTFHAVYFFLPSVYIVFIIIFWEGLLGGGVYVNCFAEIMENVPPEDREFSLGATTVSDSGGISIAGLISIVMETKLCNYQVAHGRDWCRRISAQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5B0</accession>
    <name>X0C5B0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_17372</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658557">
        <property type="protein sequence ID" value="EXK77942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5B0"/>
    <dbReference type="HOGENOM" id="CLU_028200_0_0_1"/>
    <dbReference type="OrthoDB" id="5417844at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="38"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="320"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK77942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="376" mass="42472" checksum="D1B3836E09FB4D3A" modified="2014-05-14" version="1">MASQLELSDVEFMTKGYRNRTILVFSICFPLAVLTVSLRFFSRVLAKNPFWWDDWLSLTGLFMTGGFCACVLSCLPSLGLLSGKEPITNELLSHNAKGAYVAEMFYYCNQLSLKFSILMFYWRVFASSTYIRRSIYYIGVCILLWFTSVFIVSALQCVPVHANWDPIAKQRPDVKCVDLNGFFFGTSIPNIVADLVLVVLPIPQVLQLKITLTQKCFVILFFILGGFVVITSIVRLELITKVDFGTFAVNWTVDNSVLWTIVENCCGVISVCLPSLRPIIRFIPWKAFQNAFTRSYSASHESKFQPKSTVRTGTNLFERSRQRSQWSQIESTNEGQSEGHAGIRKHTEIEISSIEMASLSNSSQVRLAGVEDNSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6S8</accession>
    <name>X0C6S8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidyl-prolyl cis-trans isomerase-like 1</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Rotamase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_09638</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6S8"/>
    <dbReference type="eggNOG" id="KOG0882">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10264753at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01927">
        <property type="entry name" value="cyclophilin_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000003">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD repeat-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000450">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD-repeat protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4 10" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="109"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="12">
        <location>
            <begin position="475"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK86898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="621" mass="69624" checksum="F4505412EAF7D3BB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7Q9</accession>
    <name>X0C7Q9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transport protein particle subunit trs85-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7Q9"/>
    <dbReference type="eggNOG" id="KOG1938">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014185_0_0_1"/>
    <dbReference type="OrthoDB" id="203724at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024420">
        <property type="entry name" value="TRAPP_III_complex_Trs85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975">
        <property type="entry name" value="TRANSPORT PROTEIN TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12739">
        <property type="entry name" value="TRAPPC-Trs85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="700"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="757" mass="84109" checksum="0E3CD42C36C47E5A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7R9</accession>
    <name>X0C7R9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07254</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OPI10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7R9"/>
    <dbReference type="eggNOG" id="KOG4067">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084839_1_1_1"/>
    <dbReference type="OrthoDB" id="10248398at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048364">
        <property type="entry name" value="Hikeshi-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008493">
        <property type="entry name" value="Hikeshi-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031318">
        <property type="entry name" value="OPI10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925">
        <property type="entry name" value="HIKESHI FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925:SF0">
        <property type="entry name" value="PROTEIN HIKESHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21057">
        <property type="entry name" value="Hikeshi-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05603">
        <property type="entry name" value="Hikeshi-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hikeshi-like N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Hikeshi-like C-terminal" evidence="3">
        <location>
            <begin position="138"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK90475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="197" mass="20411" checksum="E15A49A85CBDF950" modified="2014-05-14" version="1">MSSPLFGIVPAGQPLITEPSSTPSPTSLLYALPTTKHFSHIVVFMLPGISLPPNTAAAIYLATAADVAAAAQSGGTPNFRFLGGIGPGKESAMFKVSGGGEASDLVIGVSVESEESVGQRLQELAATKSGNSSGGQPSTAILAQRIIQNAFNFLSSFSGTAGPGGVEVVPLKAFENWWRKFESRVRADPSFLEKQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C840</accession>
    <name>X0C840_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_09356</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C840"/>
    <dbReference type="SMR" id="X0C840"/>
    <dbReference type="eggNOG" id="KOG0908">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_14_0_1"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK86994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="134" mass="14403" checksum="B12CAE7517A79334" modified="2014-05-14" version="1">MAAPSSAVVEIKSKAQFDELVKTTPYVALQAHASWCGPCKAISPIFNKQAAEHKSDKYAFAKFDTDDVPDLAFELGIRSIPAFFFFENGDKASDLLGAVPPKLTAAVKTYADKATGGAAEKPAEENTLKTDENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8I9</accession>
    <name>X0C8I9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_08872</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8I9"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_1_2_1"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF13">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939203" description="FAD-binding PCMH-type domain-containing protein" evidence="5">
        <location>
            <begin position="19"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="60"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK87523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="503" mass="54900" checksum="988A4E8586304BAD" modified="2014-05-14" version="1">MHLNSLLASSLFAASALAAPSASTKKACEEISKAIPDRVSQPFTINYNSQSSGYWSTALREIKPACVVTAKSAEDVSKAVTILNKYPDVKFAAKSGGHDPNPTHATAGDGVLISLNEMVGATYDADKKVAYVKPGGEWNDVISQLNKDGVAIVGGRLGLVGVGGLLTQGGISFLSAQYGLAADNVVSWEMVNWNGTIINVDAKTQPELAVALRGSGSQFGIVTQFTVRAYPIGKVWGGIRTYDESKTDELYKAMHEFIPYSNEDPKAAIIVTSLILTGSSRINLLFYFYQGEKPPTTGAFADLLKIKSTLSTTKTQSYPDLLKSNGAGVSLLNSRISFRTATIPYFPDDSSVYAEITDKFVDITSTYFKNLRGLASQCSVDFQPLPSAIGKHTEERGGNAIGFTANDPDRVLLEIQCAWVEKRYDDTVRQFSKDLTAWIEDKLPEWIERNGGSADEYLPLFMNDAMYDQNVTGTYKDYAKFKELQREADPEGVLRERMGGFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8N5</accession>
    <name>X0C8N5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450 monooxigenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_08914</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8N5"/>
    <dbReference type="eggNOG" id="KOG0159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK87573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="58969" checksum="ED278E3A6CEDA48C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8Y5</accession>
    <name>X0C8Y5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sphingoid long-chain base transporter RSB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_09123</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8Y5"/>
    <dbReference type="eggNOG" id="ENOG502S9TD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033465_6_0_1"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF11">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10770)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK87289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="31624" checksum="4FAC62783755CF05" modified="2014-05-14" version="1">MSIADGSYARGDLLNGCKDLIPGLQNAYGYVPSLAAGIVFCLIFAATGIYHIVRSFQKRKATSYLLAISSYIELIGWIGRTWSSKCAYNKIAFLLQITTLVVAPIFVAAAIYVTLGYLIKAVGPQYSVIRPKLYLWIFLVVDVLALLIQAGGGGLASGAANKGKDTKPGANLMVAGIIFQLVSMTGFCILFAIFVLRTRGLELAKGQRFVIYATIISVVFVYIRCIYRTVELLEGWDGKLMKTEGYFIGLDGVCIAVAILIFCIFDPAVLLDHDKQPELSFNELNTVSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0C923</accession>
    <name>X0C923_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Transketolase</fullName>
            <ecNumber evidence="4 15">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_06510</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 15">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="12">Binds 1 thiamine pyrophosphate per subunit. During the reaction, the substrate forms a covalent intermediate with the cofactor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4 15"/>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK90935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C923"/>
    <dbReference type="eggNOG" id="KOG0523">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10267175at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000004">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF2">
        <property type="entry name" value="TRANSKETOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 13 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 15" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="16">
        <location>
            <begin position="356"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK90935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="685" mass="74875" checksum="CCDA063DF87175FF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9U3</accession>
    <name>X0C9U3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_08836</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9U3"/>
    <dbReference type="OrthoDB" id="1076608at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022257">
        <property type="entry name" value="PHM7_ext"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF53">
        <property type="entry name" value="DUF221 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12621">
        <property type="entry name" value="PHM7_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="507"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="556"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="611"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="649"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="725"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="769"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="799"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="11">
        <location>
            <begin position="52"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="12">
        <location>
            <begin position="221"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="509"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="10TM putative phosphate transporter extracellular tail" evidence="10">
        <location>
            <begin position="962"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="289"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="882"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="325"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="351"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="882"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK87983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1061" mass="119896" checksum="42B84082D8EAD6AF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CA93</accession>
    <name>X0CA93_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_08650</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the complex I 30 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CA93"/>
    <dbReference type="eggNOG" id="KOG1713">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042628_0_0_1"/>
    <dbReference type="OrthoDB" id="37721at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.80:FF:000002">
        <property type="entry name" value="NADH dehydrogenase iron-sulfur protein 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="entry name" value="NADH:ubiquinone oxidoreductase, 30kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01357">
        <property type="entry name" value="NDH1_NuoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020396">
        <property type="entry name" value="NADH_UbQ_OxRdtase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01961">
        <property type="entry name" value="NuoC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004733">
        <property type="entry name" value="PRK06074.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="Nqo5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00542">
        <property type="entry name" value="COMPLEX1_30K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <keyword evidence="6 11" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase 30kDa subunit" evidence="10">
        <location>
            <begin position="106"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="256"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK87744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="290" mass="33109" checksum="855EF112B41D1BF2" modified="2014-05-14" version="1">MATSISRSRALASALRPTRPSVQLRNDQAIRGLSSTARQYVAMPKESPNLRKAPRDHPSVLKAPIVNPADKYQSKSDNMHRYGAWLMGTLPKYIQQFSVWKDELTIYISPSGVYPVFSFLKYNTAAEFTQVSTITAADYPTRENRFEIVYNLLSVRHNSRIRVKTYADEASPVPSVTGLFDGANWYEREVYDLFGVFFAGHPDLRRIMTDYGFEGHPLRKDFPLTGYTEIRYDEEKKRIVTEPLELTQAFRNFEGGSSAWEPVGAGQDRTPESFKLPTPKPEEKKEEPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAN4</accession>
    <name>X0CAN4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6594 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAN4"/>
    <dbReference type="HOGENOM" id="CLU_050262_1_0_1"/>
    <dbReference type="OrthoDB" id="3546297at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046529">
        <property type="entry name" value="DUF6594"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20237">
        <property type="entry name" value="DUF6594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6594" evidence="2">
        <location>
            <begin position="66"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="280" mass="31725" checksum="3A5CD29724AE6372" modified="2014-05-14" version="1">MGCFGADNDTNRVDEETAVRGVQVDFSDDRWIVDLELDNIISNISENESWTTSFRRGFQGANDNEQPPNELGKSYRINFAVLQRIQLKQLRTKLAKHAVSLRCEAGEPQGWQDTLKDYIQALQNYEYMERRSLQPEDPFYMSGEKYQDRKLLETIIGGEAHRFEGKKVFPAIGDWQKGPDGSRSVRDTRQDNYQRNWKGGFHQRLAVAAVGGIFLMAPMWLMVLHNTLYTALVSTTVFVAVFGSMAARYLTSLMDVMSSTAAYAAVLVVFVGLITEMHDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAS3</accession>
    <name>X0CAS3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAS3"/>
    <dbReference type="eggNOG" id="ENOG502QTW7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_7_2_1"/>
    <dbReference type="OrthoDB" id="3548654at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="131"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="682" mass="77236" checksum="B017F6B6436E5E1F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBI3</accession>
    <name>X0CBI3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBI3"/>
    <dbReference type="HOGENOM" id="CLU_2542625_0_0_1"/>
    <dbReference type="OrthoDB" id="10385377at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="83" mass="8927" checksum="E24879EEF512EF0D" modified="2014-05-14" version="1">MGSVILWRGLRQHRSTKSQRRSPSDFQSSQTPRRTSRVRQVVGGDSSSGSDGDDEASSDEDLSDDSDESSVINGAVLGVIETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBM0</accession>
    <name>X0CBM0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBM0"/>
    <dbReference type="HOGENOM" id="CLU_198484_0_0_1"/>
    <dbReference type="OrthoDB" id="10273624at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="74" mass="7982" checksum="09535899E04A0D06" modified="2014-05-14" version="1">MRAIMNPLSLILTTSNSLFTSKNNDAGTHVISAIPNSATPNSPPCISSGDRRVLLVTHPYRSVAFEPRQIEGCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCU9</accession>
    <name>X0CCU9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCU9"/>
    <dbReference type="eggNOG" id="ENOG502SV8I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032833_0_0_1"/>
    <dbReference type="OrthoDB" id="2129362at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="302"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="588" mass="66291" checksum="0C82A39EF59BC96B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDA9</accession>
    <name>X0CDA9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Beta-glucosidase cel3A</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Beta-D-glucoside glucohydrolase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Beta-D-glucoside glucohydrolase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Cellobiase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Cellobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Gentiobiase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Gentiobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Probable beta-glucosidase G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">FOQG_14848</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 26">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="JH658439">
        <property type="protein sequence ID" value="EXK80642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDA9"/>
    <dbReference type="HOGENOM" id="CLU_004542_2_3_1"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF12">
        <property type="entry name" value="BETA-GLUCOSIDASE G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 22" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939314" description="Beta-glucosidase cel3A" evidence="22">
        <location>
            <begin position="17"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="23">
        <location>
            <begin position="701"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00039579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00041601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00070030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00078013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00083231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00083611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EXK80642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="785" mass="86107" checksum="4266C7F76CEBD3C8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEJ2</accession>
    <name>X0CEJ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-hexosaminidase</fullName>
            <ecNumber evidence="7">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_07894</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="7"/>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEJ2"/>
    <dbReference type="OrthoDB" id="428480at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016231">
        <property type="term" value="F:beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030203">
        <property type="term" value="P:glycosaminoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06562">
        <property type="entry name" value="GH20_HexA_HexB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000063">
        <property type="entry name" value="Beta-hexosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029019">
        <property type="entry name" value="HEX_eukaryotic_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF58">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14845">
        <property type="entry name" value="Glycohydro_20b2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001093">
        <property type="entry name" value="B-hxosamndse_ab_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937593" description="Beta-hexosaminidase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase eukaryotic type N-terminal" evidence="11">
        <location>
            <begin position="22"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="10">
        <location>
            <begin position="219"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001093-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK89224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="611" mass="68874" checksum="009F8BA3DA6AE80C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEW0</accession>
    <name>X0CEW0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDENN FLCN/SMCR8-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEW0"/>
    <dbReference type="OrthoDB" id="5599713at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037521">
        <property type="entry name" value="FLCN/SMCR8_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021713">
        <property type="entry name" value="Folliculin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037520">
        <property type="entry name" value="Folliculin/SMCR8_longin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441:SF2">
        <property type="entry name" value="FOLLICULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441">
        <property type="entry name" value="FOLLICULIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11704">
        <property type="entry name" value="Folliculin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51834">
        <property type="entry name" value="DENN_FLCN_SMCR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN FLCN/SMCR8-type" evidence="2">
        <location>
            <begin position="246"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="486" mass="51529" checksum="F90C07A965AA9B98" modified="2014-05-14" version="1">MLLTGIPTHRCHITSLPQPHDLKNGPLPLCLAHYCDLHGPTPLMVTEGLPASCTVCFEDGADPADNRPRSSAHASSTALNDALKNLDLSRSASMPASEQEAQAQRAALLRNSSNSGATPTAIDTPPESPRPAPPHPRRDSSFRRTYDETVTKKQGPCDNCAMTLPRQQAGSNSVHLANNTRGPTLRTRAPAERVFGAGGQASPPNSQTSSDTDGERDEDPRARQRITPSVSSRNTSRSSKSGGTGNSTAAERTPFHVHYVDYTSTHDPVLPDSFSLIRASCLRTLSFETLPRAPSTANPTSPVATSSPAFVTTQSAGSAVTGGPIFFGDALAGYTTAYIFRIPDVHARGHKRVYAFLALSTHRERLAMKTFAVVSTAFRELATWIQQLAEAEAERAAENSPIGSSIYGGGYAPPPPTVESSGGPDRNGSSFLTGGSGFTRRMGGGPGASAPKARGLAEIVGQPDIFIELHRRFVHLLFEVGVTLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEZ8</accession>
    <name>X0CEZ8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658428">
        <property type="protein sequence ID" value="EXK81172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEZ8"/>
    <dbReference type="HOGENOM" id="CLU_3087284_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="52" mass="6022" checksum="032B59DA393EAA97" modified="2014-05-14" version="1">MIRFGPPNPEAQARHFPSRCWLRMWRWRVPEADDLGICAEVGTLNLAVERDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CG74</accession>
    <name>X0CG74_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658424">
        <property type="protein sequence ID" value="EXK81627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CG74"/>
    <dbReference type="HOGENOM" id="CLU_100715_7_3_1"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.40:FF:000001">
        <property type="entry name" value="L-PSP family endoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00004">
        <property type="entry name" value="Rid family detoxifying hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803:SF58">
        <property type="entry name" value="PROTEIN HMF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="129" mass="13562" checksum="4F0E3D83563B3494" modified="2014-05-14" version="1">MANRLAINRPGFSSPILSEALIHNGLVYTSGKIGVDAKTGVLVSDDVAEQTKAVLGLLESVLHEAGSGLDKILKCNIYLTNINDFAAMNAVYIATIPNPKPARVCVTVSELGKGAKVEIDCIAIVEKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHK6</accession>
    <name>X0CHK6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05071</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat LST8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHK6"/>
    <dbReference type="OrthoDB" id="10248252at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037588">
        <property type="entry name" value="MLST8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842">
        <property type="entry name" value="G BETA-LIKE PROTEIN GBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842:SF2">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G04300)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="765"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="140"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="861"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="955"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="456"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="867"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="964"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK93910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1035" mass="116219" checksum="28A080F6E0393718" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CI45</accession>
    <name>X0CI45_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cut9 interacting protein scn1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CI45"/>
    <dbReference type="eggNOG" id="KOG3020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031506_3_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053044">
        <property type="entry name" value="Metallo-hydrolase/TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345:SF1">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="407" mass="45074" checksum="56869C34142EFE44" modified="2014-05-14" version="1">MCQHTHNYDEPQQSKPEPAGDQPPFPWHLPICDAHCHPTDTMASVTDIPSMRAAALTIMATRAQDQDLVTDVASNHSNPDLKSLLQGKSEATDTCAIPSFGWHPWFSHLLYDDSADTPTFQSISGSETDNAAKQAHYNAVLQPVPSPDFVASLPSPIAISSFLNATESRLSTSSCALVGEIGLDKAFRLPEPWQPSDHVERDSTLTPGGREGRQLSPYRVKIEHQRDILAAQLRLAAKARRAVSVHGVQAHGILYETLAATWKGHEREVITRRKRRLVASGAEDFSDDDDDDDGSDKPYPPRMCLHSFSASVEVLRQYLNRTIPARIFVSLSTAVNLSTDASRNKTDDVLRALPDDSILVESDLHIAGKQMDSALEDMYRHVCRVKGWNLDEGVKKIARNYEEFIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CI81</accession>
    <name>X0CI81_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4-coumarate--CoA ligase-like 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_06787</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CI81"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_2_1"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000007">
        <property type="entry name" value="4-coumarate--CoA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF424">
        <property type="entry name" value="ACETYL-COA SYNTHETASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="29"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="468"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK90539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="568" mass="62333" checksum="05D6F8A5A99A20C6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIW8</accession>
    <name>X0CIW8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AarF domain-containing kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06673</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIW8"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF19">
        <property type="entry name" value="AARF DOMAIN-CONTAINING PROTEIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="173"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="597" mass="67149" checksum="FC3BEA06A16217DC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJD8</accession>
    <name>X0CJD8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJD8"/>
    <dbReference type="HOGENOM" id="CLU_3068700_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="53" mass="6053" checksum="6606C1F3CFAF902D" modified="2014-05-14" version="1">MPRNGRRHGVRGYLFLTFSVFPHGIQELGFDEEGDDSKHSQASPAQYKPRGYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CL62</accession>
    <name>X0CL62_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyl hydrolases family 39 N-terminal catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_12459</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 39 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658404">
        <property type="protein sequence ID" value="EXK83277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CL62"/>
    <dbReference type="eggNOG" id="ENOG502RXFG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023231_1_0_1"/>
    <dbReference type="OrthoDB" id="3445803at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049166">
        <property type="entry name" value="GH39_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01229">
        <property type="entry name" value="Glyco_hydro_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolases family 39 N-terminal catalytic" evidence="4">
        <location>
            <begin position="160"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK83277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="462" mass="51564" checksum="80DE2F674AE0AEE4" modified="2014-05-14" version="1">MPEEYISMLKSLPSEVDKVKEPVVGVATVDVTLQTGPPRHLASGILYGIPDRPDQIPDHFYKDLGFNYGRGGGSQLPGTKGYAVSLEDYKARFASALSNYRTTRKHGGEFIYLLPAAWGADGGQSENFAYPGDNDDWTSWDAFLERTLDDVKKSDMIEGLVIDTWNEPDLSFFWNRSMEQWLELWTRSFKKIREALPSVRITGPSMSAIPSTSHEWWSAFLSRCKDSLPDQWSWHMEGGDEAVTMASSMASFHDLLSKHDIPLDKAQDVNINEYAIYGEQVPSAGAWWIAGLERENAHGLRGNWAIAGALHDFMAGLLSKPNGSDGSYAIEGQGYWPTAEFQVYRYYASSMKGQRLRTTASSDGLFDAYATVEGDVVRILAGTRSRPGNWTLDVVGLTGDTRVKVKTLAFRVVDGDKFKRVDGPQDLGEREELVKDCKLKLRMKHQDPTTAFAFELAIAWGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMP6</accession>
    <name>X0CMP6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11967</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the 2nd section; belongs to the type-I 3-dehydroquinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the shikimate kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMP6"/>
    <dbReference type="eggNOG" id="KOG0692">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008871_0_1_1"/>
    <dbReference type="OrthoDB" id="4415835at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00502">
        <property type="entry name" value="DHQase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000386">
        <property type="entry name" value="Quinate repressor protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089:SF1">
        <property type="entry name" value="BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="SHIKIMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01100">
        <property type="entry name" value="SHIKIMTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="5">
        <location>
            <begin position="498"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase" evidence="4">
        <location>
            <begin position="630"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="SDH C-terminal" evidence="6">
        <location>
            <begin position="781"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="675"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK83807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="824" mass="92279" checksum="70389F9968557329" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNM7</accession>
    <name>X0CNM7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitinase</fullName>
            <ecNumber evidence="2">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="2"/>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNM7"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_1_2_1"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000677">
        <property type="entry name" value="Chitinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF228">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00551">
        <property type="entry name" value="2SGLOBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="3">
        <location>
            <begin position="18"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK96055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="357" mass="38684" checksum="BB60327145DE43EC" modified="2014-05-14" version="1">MSSSRKSRIASSMSNVMFTNAVYFPNYRIYQGDTPGMLNYSCINHVYYAYASVSADGGVFLSDEWADAGAPVDGVQGGLGSLMHLKQKHPHLRVVLSIGGGNSSEIFPLVASSTLLRDNFARSAKGLVEASGLDGIDIAWEYPCDVQQGYDFLALLAAVRIHLPEEHYVLTAALPAAKSILQFLDLMEIAEYLDFINLMAYDFFGSWTPKAGHHAQLYAMDKEETSASSGVSYLMSKGFPPKKILLGIPTFGRSFLHCTGAGHKYKGVGGAEDGTFEYNQLPRKGCKEVVDKRHVAAHCTGADGGFVTYDNPDTVKIKAGFCKQKGLGGLFYWNGPADSKDKSRSLVAAGFRALHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP86</accession>
    <name>X0CP86_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP86"/>
    <dbReference type="eggNOG" id="ENOG502SRS2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071330_0_0_1"/>
    <dbReference type="OrthoDB" id="3535423at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097:SF9">
        <property type="entry name" value="EPIMERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097">
        <property type="entry name" value="OXIDOREDUCTASE HTATIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="7"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="227" mass="25092" checksum="FC9613200BCB809B" modified="2014-05-14" version="1">MKLIVTGANGYVGSEIIRQSLKLPQVTSVVAVSRKLVSPPAGTIPTRFESVVVQDYGTYPDHVRDAFRGADACIWTVGITPMVYRSLDPAQARKICVDDTLAGLQNIVKSSTNKPFRFLYMSGADAETDQTKTPPVMPEYFLMRGEVENQVMGFAKQHPDEVVACVARPGFIIDDSTDVQALKYRMQKDVTVIRVESVAAALLHQALNGFDKEILWTDDMRSFDETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPG7</accession>
    <name>X0CPG7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPG7"/>
    <dbReference type="HOGENOM" id="CLU_1959689_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="108" mass="12247" checksum="49BDB37987CEC9F4" modified="2014-05-14" version="1">MDLSLPKRNCDSQHCGFFGSELTASRRFLETRLRGKDQGAKQSVADDKRLGRLAARSADLLLRRNLEQYEKRIRNLQHSLPNGEKERATNKEAKDPGNFLAATNTPIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQQ0</accession>
    <name>X0CQQ0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">STE24 endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQQ0"/>
    <dbReference type="HOGENOM" id="CLU_194744_0_0_1"/>
    <dbReference type="OrthoDB" id="5341873at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="74" mass="8109" checksum="F50D5699C4CD8E5E" modified="2014-05-14" version="1">MSTRLDNFMKSKNVVLFFGGVVSMAAAYTIWGNDGQGVFPPQPDPTGDPKTWTKEECQLWLNKASESLTVVDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRG6</accession>
    <name>X0CRG6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRG6"/>
    <dbReference type="HOGENOM" id="CLU_2277653_0_0_1"/>
    <dbReference type="OrthoDB" id="5092449at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="116" mass="13575" checksum="7539115C5F417ABD" modified="2014-05-14" version="1">MSEEARWSSLDDLTMYDEALRKSETDTDSEPVEESDDETEIDYNDEDTNDDPDSEALQEAKAEIEDLYDLIYWKTCEITYLTNLNWSLEEHNLCLEKEVEVLKAKLEAINKEPTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRV7</accession>
    <name>X0CRV7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sodium-and chloride-dependent GABA transporter 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_10868</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRV7"/>
    <dbReference type="HOGENOM" id="CLU_016501_0_0_1"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11554">
        <property type="entry name" value="SLC6sbd_u2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="547"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="576"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="619"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="636"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK85217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="651" mass="71804" checksum="1F54BDBE5F6B40C5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSJ1</accession>
    <name>X0CSJ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">FOQG_04403</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSJ1"/>
    <dbReference type="SMR" id="X0CSJ1"/>
    <dbReference type="eggNOG" id="KOG2788">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029942_1_0_1"/>
    <dbReference type="OrthoDB" id="10262326at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EXK94273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="468" mass="52468" checksum="590E1BD853AD24F3" modified="2014-05-14" version="1">MTTTMMTSLSRSETLTLSTVSAAAFAVLANTLHGDGEPLMASLALSVLAFALCFAMIRWLGPTFMRAGFQGRDMSKANRAEIPECMGAVCAAVYLLSVIVFIPFPFYKDIVAATSGGGNRDVVVELQHVNQGRFLHRFPHNKLASFLGAIISLQTIALLGIGDDLFDIRWRHKWWIPGLASIPLLVVYFVDFDVTSIVLPLQLQPYLGELVDLGFLYYVYMACVAMFCPQSINMLAGINGIEVSQCIVIAFLLVFNDCLYLFTPYPHPATDSHLFSLYFLLPWIGVSFALLLHNWYPAKVFVGDTYCYFSGMVFAVVGILGHFSKTLGLLLVPQIFNFLYSCPQVFGLIPCPRHRLPHFNARSGLMEPSVTPWSPERQPHPLVAQGLHFLNRLRLVKVTTDEKGQFVETSNFTILNLWLVWRGPLREDRLAFEITMLQLVAGFFGLFVRHRLALLVFKEDNWGTAAQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU53</accession>
    <name>X0CU53_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU53"/>
    <dbReference type="HOGENOM" id="CLU_2654539_0_0_1"/>
    <dbReference type="OrthoDB" id="4983377at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="78" mass="8993" checksum="2A7306DA872D2351" modified="2014-05-14" version="1">MQGPKDDNDPYYHVPALEDMLETTWAVVVKSRNAIAEVGDGNANRQMHFERTYQYEFDGRILTADHLVQREAQIRAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUK6</accession>
    <name>X0CUK6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">40S ribosomal protein S20</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03740</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUK6"/>
    <dbReference type="SMR" id="X0CUK6"/>
    <dbReference type="eggNOG" id="KOG0900">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122625_0_0_1"/>
    <dbReference type="OrthoDB" id="10248551at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.600:FF:000004">
        <property type="entry name" value="30S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_uS10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005729">
        <property type="entry name" value="Ribosomal_uS10_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01046">
        <property type="entry name" value="uS10_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="6">
        <location>
            <begin position="20"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="116" mass="12919" checksum="D796FFBC21F5EBD0" modified="2014-05-14" version="1">MSHQKNEKDVGDAPKSHRIRITLTSRKVQSLEKVSAELIERARSKGLTIKGPVRLPTKNLKITTRKTPCGEGSKTWDSYELRVHKRLIDLHAPTEVVKSVIVNIEAGVEVEVTIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXV9</accession>
    <name>X0CXV9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXV9"/>
    <dbReference type="HOGENOM" id="CLU_3159990_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="48" mass="5648" checksum="17B570A03806CD76" modified="2014-05-14" version="1">MRRLANERAKKYLEPRDISWKKWDAFGDDESNGTEAVPTGWYSISRCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY81</accession>
    <name>X0CY81_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_09232</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY81"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_1_1_1"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="45"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK87432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="484" mass="52939" checksum="81E680E5DA9577C2" modified="2014-05-14" version="1">MTTLTPQPSIPQAESLIAAGLEARILTPTDAEFSARQESYWSNSAKIKPACIVQPRTPEEVASVVKALVSAGQRFAVRSGGHTNWAGSNNIEGGVTIDLVHLNHVSFDAATETADIGPGCRWREVYAELSKHGRAVAGGREGNVGVAGLLLGGGNAFFTARQGFGCDNVVSYQVVLANGDIITADEKNNTDLYRVLKGGSNNFGIVTKFTMKAIKSDKVWGGMTFFPKQVIPGAIEALSAFTDNVPNDIHSNLVTIFTHMPDFKDIVVATLYANMEGIEKPPAYEKWLALPEIMNTVKNTTLTEMAFEYNIPANFYDTWFTCCFKNDTRIITKASELHDKLVEELKAFIPDGNFITQCLFQPLPTLFGQRGIEAGGNIMGMDRHKTNGILFLAVVMAQTPEQEAFARPKVQAWIKDVQEFAATIEGGNLEWTYLNYADKSQDPLGSYGAENIKKMKDAAAKYDPEQVFQKLVPGGFKLSDVKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYI0</accession>
    <name>X0CYI0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYI0"/>
    <dbReference type="eggNOG" id="ENOG502RF8N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015502_2_0_1"/>
    <dbReference type="OrthoDB" id="2399539at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="543"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="549"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK87532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="605" mass="66923" checksum="EED022AD8AEF636D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYU4</accession>
    <name>X0CYU4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03224</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYU4"/>
    <dbReference type="eggNOG" id="KOG0718">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019611_0_0_1"/>
    <dbReference type="OrthoDB" id="666364at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024586">
        <property type="entry name" value="DnaJ-like_C11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052243">
        <property type="entry name" value="Mito_inner_membrane_organizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11875">
        <property type="entry name" value="DnaJ-like_C11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="638"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="4">
        <location>
            <begin position="128"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK96039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="812" mass="89557" checksum="38B99551B1FB3571" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0C3</accession>
    <name>X0D0C3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0C3"/>
    <dbReference type="HOGENOM" id="CLU_2722359_0_0_1"/>
    <dbReference type="OrthoDB" id="5071137at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="72" mass="8095" checksum="0C728258334FB996" modified="2014-05-14" version="1">MASAARFEQELKTVGTIKQRLATIDKGNPVIARLREELVKSAEREDLESLAQKVSEEHKHELREARLVGVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2B2</accession>
    <name>X0D2B2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_02510</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1035">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="341578at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004694">
        <property type="term" value="F:eukaryotic translation initiation factor 2alpha kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990625">
        <property type="term" value="P:negative regulation of cytoplasmic translational initiation in response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009893">
        <property type="term" value="P:positive regulation of metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14012">
        <property type="entry name" value="PK_eIF2AK_GCN2_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23823">
        <property type="entry name" value="RWD_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14046">
        <property type="entry name" value="STKc_EIF2AK4_GCN2_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000050">
        <property type="entry name" value="eIF-2-alpha kinase GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000009">
        <property type="entry name" value="Eukaryotic translation initiation factor 2-alpha kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000821">
        <property type="entry name" value="Serine/threonine-protein kinase gcn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000074">
        <property type="entry name" value="Serine/threonine-protein kinase gcn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016255">
        <property type="entry name" value="Gcn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024435">
        <property type="entry name" value="HisRS-related_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF136">
        <property type="entry name" value="EIF-2-ALPHA KINASE GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12745">
        <property type="entry name" value="HGTP_anticodon2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000660">
        <property type="entry name" value="Ser/Thr_PK_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RWD" evidence="15">
        <location>
            <begin position="48"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="268"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="596"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="162"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="213"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="561"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="664"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="714"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="561"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="664"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="675"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="715"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="741"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="821"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="602"/>
            <end position="610"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="625"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="626"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000660-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000660-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK97249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1604" mass="181327" checksum="6B8D1B5435EB4BDD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2M3</accession>
    <name>X0D2M3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein AF-9 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_00905</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2M3"/>
    <dbReference type="eggNOG" id="KOG3149">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051385_2_0_1"/>
    <dbReference type="OrthoDB" id="16041at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16908">
        <property type="entry name" value="YEATS_Yaf9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573:SF1">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="YEATS" evidence="8">
        <location>
            <begin position="10"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXL01021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="268" mass="30263" checksum="5729841B802E9B9B" modified="2014-05-14" version="1">MAPQNQLGKRVKLTQVRRPFIVGSTAKPFSDTNPRPAGVPDTHTHSWQVFVKGLDDTDITYWLRRVQFKLHESIPNYVRMVEGEPGKPFVVEETGWGEFDITIKLYYVNDSGEKPQTLYHYLRLHPYGRNEEEKQAMIASNGEIRAWSYEEQLFNEPYEVFYNLLTQGAVPKGWKPSGGKGKGKTRAPPPFPTDSNEVWEHSAMIPAHNRPGQPFSLETEAAEIRKLADAQTQAEDMAKRILAELKAKEELLAKLKGENQAAAAAAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3W3</accession>
    <name>X0D3W3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF962 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3W3"/>
    <dbReference type="eggNOG" id="KOG3292">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081702_1_1_1"/>
    <dbReference type="OrthoDB" id="2124888at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046521">
        <property type="term" value="P:sphingoid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026:SF9">
        <property type="entry name" value="2-HYDROXY-PALMITIC ACID DIOXYGENASE MPO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026">
        <property type="entry name" value="DUF962 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G05310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="Mpo1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="21098" checksum="E3371737E547519E" modified="2014-05-14" version="1">MSLDLEQHLTFYGAYHHNSVNVAIHMVCVPLILLSGFCMATYTGTLIPTPSWITPPYLDLNLGVIGASLYSLLYLLLEPFAGFLLALFCMGGAALGNYLHQQNPDTTFQGALAIHIVCWIFQFIGHGKYEGRAPALLDNLIQAVFLAPMFVWLEILFKFGYRPELRSRVNKKVQVEIEKFKSKNGKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4B3</accession>
    <name>X0D4B3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polymer-forming cytoskeletal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4B3"/>
    <dbReference type="eggNOG" id="ENOG502T0K4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087646_2_0_1"/>
    <dbReference type="OrthoDB" id="5194604at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL01222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="18058" checksum="F6CBDEF2FCB0DB0C" modified="2014-05-14" version="1">MASYYNTTSSYASPPAFKRSRSIKSDHEIDLNGPIEVVGSVKSGSSISLNGDVIVREKVDAYGSLGLNGSIRCDGKVKAYGNILVNGYTVANDKIKGCGKLRVVGTLEATDLEIYGNVSITGLLKCRRLIVYGTLTLIGSDSSYYVEESEQVAGAVMMRETEPDWDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D651</accession>
    <name>X0D651_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_01473</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D651"/>
    <dbReference type="eggNOG" id="ENOG502QTAT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008220_0_0_1"/>
    <dbReference type="OrthoDB" id="38531at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057688">
        <property type="entry name" value="DUF7928"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408:SF3">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25550">
        <property type="entry name" value="DUF7928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="691"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="730"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="772"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="823"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="855"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7928" evidence="4">
        <location>
            <begin position="79"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="501"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK98619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="884" mass="99053" checksum="423D3DFAFE2FF741" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7H6</accession>
    <name>X0D7H6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phytanoyl-CoA dioxygenase domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_06817</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PhyH family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7H6"/>
    <dbReference type="eggNOG" id="KOG3290">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048953_0_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF15">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK90587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="33840" checksum="68886D343E557425" modified="2014-05-14" version="1">MTTDTPGLSPDQLDTFNRDGYLILPGALSSSTVKSLLDETHNLLETFSLDDHPLTRFSTGEKRDHVGDDYFLTSGDKVRFFFEEDAFDDDGKLTKPKARAVNKIGHYLHALSPPFARLLDHDTSKVSPPAVARSLGFKDPRCLQSMVICKQPEIGGAVPPHQDSTFLYTNPPSAVGFWYALEDATLENGCLSFLPGSHLWAPVEKRLVRKAGNVGTEMVDNDGPKFPAAVGYGQAAPDGQHEYVPGEVKAGDLVLIHGNLLHKSEKNISQKGRIIYTFHIIEGQDRDYDDKNWLQPPNEGFTKLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DE69</accession>
    <name>X0DE69_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab GDP dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DE69"/>
    <dbReference type="eggNOG" id="KOG1439">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021695_0_1_1"/>
    <dbReference type="OrthoDB" id="9446342at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.405.10:FF:000001">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="464" mass="51482" checksum="CAD2B6ED78EED358" modified="2014-05-14" version="1">MDEIAPEYDVIVLGTGLTECILSGVLSVKGKKVLHIDRNDHYGGEAASVNLETLFKKYGNFREGEEPWKQYGRLNDWNIDLVPKFLMSSGELTNILVSTDVTRYLEFKQVAGSYVQQGASNKATVAKVPSDAAEALRSPLMGIFEKRRMKSFIEWVGTFDPKDPATHKGLDINKCTMKDVYDKFGLEATTKDFIGHAMALYLTDDYITTPGQAPEAIQRIRLYGNSVARYGKSPYIYPLYGLGELPQGFARLSAIYGGTYMLNTNIDEIQYEGDKAVGIEATMTGVEEMKFKTKAKMILADPSYFPNKAKVVGHVLRAICILKHPLAGTNDADSAQLIIPQSQVGRKNDIYIACVSSAHNVCPKGYWIAIVSTIAETSANHHVELQAGLDRLGKIEEQFMGPPIPIYEPLEDGTKDNIFISKSYDATSHFETTTDDVKDIYRRATGEELKVEGLREGIQVAEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0DFJ7</accession>
    <name>X0DFJ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cholesterol 7-alpha-monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DFJ7"/>
    <dbReference type="eggNOG" id="KOG0684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018012_0_0_1"/>
    <dbReference type="OrthoDB" id="3366823at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24306">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24306:SF7">
        <property type="entry name" value="AHBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="569" mass="65136" checksum="6C7227BECF8FDFC1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0DJN9</accession>
    <name>X0DJN9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Autophagy-related protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_04625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays a role in autophagy. Functions at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions. Also plays a role in mitophagy and regulation of filamentous growth.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG29 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DJN9"/>
    <dbReference type="eggNOG" id="ENOG502S3V4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027589_1_0_1"/>
    <dbReference type="OrthoDB" id="21072at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2570:FF:000001">
        <property type="entry name" value="Autophagy-related protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039113">
        <property type="entry name" value="ATG29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040666">
        <property type="entry name" value="Atg29_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039362">
        <property type="entry name" value="ATG29_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40012">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40012:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18388">
        <property type="entry name" value="ATG29_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Atg29 N-terminal" evidence="9">
        <location>
            <begin position="6"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="87"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00060351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK94612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="412" mass="44138" checksum="C0AD90EE11072FB2" modified="2014-05-14" version="1">MAEPTYTIFVRVPMPRGDFVDPPPVNWDSVKDEALWKILSGAAKKQIDWDEVADRFEVPVDFLLQQVAYLTERHASQVRAQVRKATAAVRGSVQSPVPGGDSAGPGHQRTHSALSIRKDSPMPRAEAGSGTGTPLNASIRPIVSRNPSTNTTVLRDMTGGSASPRPGTGLASRTGERRRLSSLPISSVPDRSPDRVAQPEPAPDERSPSPGPAEDSSPTSSEDESSPAQSRIIRRPPRFQQPDGGQYEDDDDDESEPAFQPYTSPSNQTSAQDLGSTLRGDGRSSGKRHHRPHGKSAIHQSHTSDSSASSAAMVQKPDKSDKTTEQRTPGPLSPRRTAELAGRSPGNQSKGYSREGSDGTPSMGSSYSDLDDASVTQSALEEALASHMNRGAGSRFSISQAFRSRYNPGPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0DKE6</accession>
    <name>X0DKE6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DKE6"/>
    <dbReference type="SMR" id="X0DKE6"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025000_1_2_1"/>
    <dbReference type="OrthoDB" id="8093034at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043488">
        <property type="term" value="P:regulation of mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12614">
        <property type="entry name" value="RRM1_PUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12619">
        <property type="entry name" value="RRM2_PUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000117">
        <property type="entry name" value="Nuclear and cytoplasmic polyadenylated RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000224">
        <property type="entry name" value="Nuclear and cytoplasmic polyadenylated RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000134">
        <property type="entry name" value="Nuclear and cytoplasmic polyadenylated rna-binding pub1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF5">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="84"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="174"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="300"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="418"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK94837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="474" mass="51098" checksum="D6782820E8FA13C0" modified="2014-05-14" version="1">MADAGTPSNPGQLPPPPQAGAGAPGFEAGQNGQPMAPPPLHIPQNTNPIPTAITSPRSAADQGGIMSPTSAGGFRRAAPEPNKRALYIGGLDQRVTEEVLRQIFETTGHVQNVKIIPDKNARGYNYGFVEYDDPGAAERAMQTLNGRRVHQSEIRVNWAYQSNTTNKEDTSNHFHIFVGDLSNEVNDEVLLQAFSAFGSVSEARVMWDMKTGRSRGYGFVAFRDRPEAEKALSSMDGEWLGSRAIRCNWANQKGQPSMAQQQAMQAMGMTPTTPYGHHQFPAHGVASYEVILTQTPSWQTTVYVGNLTPYTTPNDVVPLFQNFGFVVESRFQADRGFAFIKMDTHENAAMAICQMNGYNVNGRPLKCSWGKDKTPSAQGAFDPAQPYSPQSAQAPGFPGTPTYYPQYGAQYGGQPGNYGGPQTGSPAGYAGSPMGYAAPQSAGGYGRGQQPPNAEWAQPRPGQNFNNGFGGYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0DLH7</accession>
    <name>X0DLH7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">LON peptidase N-terminal domain and RING finger protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_03843</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DLH7"/>
    <dbReference type="eggNOG" id="KOG4159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="264917at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16514">
        <property type="entry name" value="RING-HC_LONFs_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF42">
        <property type="entry name" value="LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN C14F5.10C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="250"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Lon N-terminal" evidence="7">
        <location>
            <begin position="337"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="449"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="491"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK95197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="611" mass="68258" checksum="7327C0211C0F341A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DS59</accession>
    <name>X0DS59_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Argininosuccinate synthase</fullName>
            <ecNumber evidence="3">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_02427</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the argininosuccinate synthase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="3"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DS59"/>
    <dbReference type="eggNOG" id="KOG1706">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032784_4_2_1"/>
    <dbReference type="OrthoDB" id="1688907at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000053">
        <property type="term" value="P:argininosuccinate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000050">
        <property type="term" value="P:urea cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="ASS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000019">
        <property type="entry name" value="Argininosuccinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1260.10:FF:000003">
        <property type="entry name" value="Argininosuccinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="entry name" value="Argininosuccinate synthetase, chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048268">
        <property type="entry name" value="Arginosuc_syn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048267">
        <property type="entry name" value="Arginosuc_syn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001770">
        <property type="entry name" value="PRK00509.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587:SF2">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20979">
        <property type="entry name" value="Arginosuc_syn_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="Argininosuccinate synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arginosuccinate synthase-like N-terminal" evidence="12">
        <location>
            <begin position="5"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Arginosuccinate synthase C-terminal" evidence="13">
        <location>
            <begin position="178"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK97107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="415" mass="46442" checksum="FDECC826160D7615" modified="2014-05-14" version="1">MSKGRVCLAYSGGLDTSTILKWLILEGYEVVCFLADVGQVEDFDAVEKKALALGAERMIIENLQKEFVEQIVFRAIQCNAIYEDRYLLGTALARPVIARAQVRVAEKYNCNLLSHGCTGKGNDQVRFELAFKACNPSIKVIAPWRLPEFCEKFQGRQDLLKFAAENNIPVSSTPKAPWSQDENLVHCSYEAGILEDPDHTPPKDLWTQTVDPLEAPDKPLDFTVYFEKGLPVKVATPDQEATDSVELFKLLNKIGHDHGVGRIDIVENRWIGLKSRGCYDTPGLTIARLAHVDLEGLVLDSKVRKLRDQFVTIEWSQCLYNGMYFSPEREWLDEAIVSAQKGVNGQVRLRAYKGNVYVLGRSSETSSLYSQEDASMDSLDTFSPMDSTGFIAIQSIRLEKYGAQKAKDGQPLSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0DVY7</accession>
    <name>X0DVY7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BPL/LPL catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01291</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the biotin--protein ligase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DVY7"/>
    <dbReference type="eggNOG" id="KOG1536">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006150_1_1_1"/>
    <dbReference type="OrthoDB" id="10250105at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin--[biotin carboxyl-carrier protein] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03144">
        <property type="entry name" value="GATase1_ScBLP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019197">
        <property type="entry name" value="Biotin-prot_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835">
        <property type="entry name" value="BIOTIN PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835:SF5">
        <property type="entry name" value="BIOTIN--PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09825">
        <property type="entry name" value="BPL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="388"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK98357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="669" mass="73658" checksum="36E442191D23E7A3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0E0X4</accession>
    <name>X0E0X4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00336</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E0X4"/>
    <dbReference type="HOGENOM" id="CLU_2197126_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="108" mass="11780" checksum="2906EC480EC9E62A" modified="2014-05-14" version="1">MARVANPTTSQALMDEVVHSIVLLKFVANKTAFQQSLVDLEFVGNVRRQGGTGGHKSEDAHSGQGDYQSGVICFNPLSLAGVPIDDRLFHGRRFGQAWIKLHKLAACF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-09-13" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1R4</accession>
    <name>X0B1R4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658769">
        <property type="protein sequence ID" value="EXK76070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1R4"/>
    <dbReference type="HOGENOM" id="CLU_1704314_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="17716" checksum="308E1EB84870300C" modified="2014-05-14" version="1">MAEVMELGVPRCTDSQTMQELKRRIRWSLFMADYWQGAIKGSSLLCTAKELGKCEILHTKVGQGVVIDSSALLHTALFGKEDETVEAQSSLQSNFEVLQELALYRPSLELTVRRFTVFQRGCMQRAFSDLHQFDKRALAFLQEHHLTLDERFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2E3</accession>
    <name>X0B2E3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979553">
        <property type="protein sequence ID" value="EXK76275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2E3"/>
    <dbReference type="HOGENOM" id="CLU_028279_1_1_1"/>
    <dbReference type="OrthoDB" id="3499148at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="392" mass="42678" checksum="7013E0DA8F4BAC0B" modified="2014-05-14" version="1">MTGQAPSQAGPDISISEPCSISDPNKTIDAITKKLSVYLAAKHSPPFTAPAGFDDALNALESPDHIVQVFLSRGFWCWLAYFLATKDPKTQPPLSLSGIPYDTLSVIAGLVSEAPVDDTLVKRIQSTLWVARRGSTRRSDLSKAGISGFPPRPSTMPVSHPEANSLKRPRGQFFEDPDEPAQVAQRPRLNNTILDTTIPVSLPAAGQPTQELHSLDHISQPMLKVNPPDGYKWPDARRIPSVFPPELGDMIARNGHKASVFALFPPDAAKCRLLLNIEAAKVSPLVMRLYGIQIVEIEQQRALALPGGVNAIISGSVQFTKTKLSLWGELFGDLIIQGVQNSRGYLDEVARGIMLSKCLSMEVPSATDHPAKITITINEFALNDIITRLWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6J4</accession>
    <name>X0B6J4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Benzoate 4-monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_17571</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979377">
        <property type="protein sequence ID" value="EXK77735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6J4"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF29">
        <property type="entry name" value="BENZOATE-PARA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK77735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="56862" checksum="4796982130D071DC" modified="2014-05-14" version="1">MSTDSMLLSPWAPLAVLLCGLLFYIIPYFYTYRHLRGIPGPLLARFSDLWLLYICRQSKRSYTVYDLHERLGPVVRIQPNHVSIVDERAINLVYGHGNGLEKSSWYDSSISLTRSIFTARKRAEHARKRRYIAHSFAPKSSRAAEGPIADKVELLVSKWDEIIDKGPQFDGLTQLECRRWFTYLSFDITGDLLFSEPFGMLENGSDLVKIDSKPGSYVSMMNSLAQRSAAVATLGVLPWLKPHAHHLPDPFFHRGMDGLQNLLGVTSAHVKERMAAAQDNHDDWLSLLLRARDDQGELLKFEELASESLTLFMAAIETVSNTLSAMMYYLATSPSSLQKLQAEVDSIDIPGTVPPFTNVRALPYLDAVLNETMRLHSVLGIGLPREVLPGSKGVHLDSFYFPPGTVLSVPIYAIHRSRDIWGQDANMFRPERWDKLSKRQKTSFIPFGHGPAACVGRNLAEVEMKIIAATLIRRYTFHMVDSEIESTEGTTRKLIKVNIGIKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0B724</accession>
    <name>X0B724_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_17365</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658557">
        <property type="protein sequence ID" value="EXK77935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B724"/>
    <dbReference type="HOGENOM" id="CLU_044876_3_3_1"/>
    <dbReference type="OrthoDB" id="9974981at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF1">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK77935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="305" mass="32834" checksum="C87C2BE1C70309F7" modified="2014-05-14" version="1">MAHEIKNVALAGASGSLGSHILQALVKAGRFNVTILTRKVNDNVPSGTAVKVVDYESASDLASALKGQDALVDATSVPDPSLAIRLMDAAVSAGVYRIVPSEFSSDPTNSKGRSLPPFQGKAKALEYVQKLADTGKITWTAISNHAFLDWGLRMSFLGVDLQNKNIKYLKPGTTIIPMTTLESVGTAVTNALIKAENTKNRICYICSTQKTQKDLAELSKQALGEEGWKSKDVDTEDAFNKAMAKLQAGQVDMQVIGDIIRFSISTPGYIDRLEKTDNDLLGVKAMSDEDVKELIRKIALETTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB15</accession>
    <name>X0BB15_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658474">
        <property type="protein sequence ID" value="EXK79350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB15"/>
    <dbReference type="HOGENOM" id="CLU_093226_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="261" mass="30110" checksum="22D9D4734BCDB632" modified="2014-05-14" version="1">MAPVFGKMNESESVTTADEQERIISYLNRKQAEIRLLNEKEAEIVIPTETSNEIFTADPCLDLIDRLNWIHQTTEAWRFVSCELCFIIKGGPEPNHGLDRCEQWPASKHAKRILQWLTTLKIPRYYNVRGACSMCGHGWFVCDEMGQGELARREARSQRSSSGKANLVKEYDAASDHDGYCMNKPVVRRIVAALCAYDDQILGKVLTKMALDHEGIDLTSESQARLWLEQRIQSQDDYWVSRLIYVLDQLIMAYDFRRSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBE8</accession>
    <name>X0BBE8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Vacuolar import/degradation Vid27 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979805">
        <property type="protein sequence ID" value="EXK75804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979805">
        <property type="protein sequence ID" value="EXK75805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBE8"/>
    <dbReference type="HOGENOM" id="CLU_2573949_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013863">
        <property type="entry name" value="VID27_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08553">
        <property type="entry name" value="VID27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vacuolar import/degradation Vid27 C-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="81" mass="8801" checksum="89EDBC7DC429EE4D" modified="2014-05-14" version="1">MTQLPVLSDGVTDIDVSTEGRWILGTTNNYVRCGARVTPTIRGGQALPTGPSRLQLQLRRRITVTLASSITTTSTFLAELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD80</accession>
    <name>X0BD80_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peroxidase</fullName>
            <ecNumber evidence="10">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_18805</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O2 + AH2 = A + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30275"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the peroxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JH658718">
        <property type="protein sequence ID" value="EXK76454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD80"/>
    <dbReference type="HOGENOM" id="CLU_025424_3_1_1"/>
    <dbReference type="OrthoDB" id="407695at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070301">
        <property type="term" value="P:cellular response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08200">
        <property type="entry name" value="catalase_peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000004">
        <property type="entry name" value="Catalase-peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000763">
        <property type="entry name" value="Catalase_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555:SF0">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555">
        <property type="entry name" value="HYDROPEROXIDASE I, BIFUNCTIONAL CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00460">
        <property type="entry name" value="BPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 10 12" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="11">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="11">
        <location>
            <begin position="209"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK76454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="492" mass="54100" checksum="DE47DA5053068A98" modified="2014-05-14" version="1">MGMDDEETAALIIGGHTLGKAHGAVSSKNIGPEPMAADLGEMGLGWHNSVNEGNGPDQMTSGLEVIWSTTPTKWSNHFLKSLLGNNWTLVESPAGHKQWEALDGKLEYPDPFVKGKFRRPTMLTSDLALINDPAYLKICKRWHDHPKQMNQAFARAWYKLLHRDLGPIARYLGPEVAKEKFIWQDPLPERKGDIISEDDISSLKSTILSTDGLTVSKLVSTAWNSASTFRGTDKRGGANGAHIALEPQVNWASNNPKQLKQVLSALKKVQKDFNSKSGPKQVSLADLIVLGGVAAIEKAAQDAGFKDVEVPFTPGRVDATQNQTDLVQFGYLEPVADGFRNYGHGTARARTEEILVDRAALLTLTPPEMTVLVGGLRALNANYDGSSNGILTEKKGQLTNDFFVNLLSPAFVWTKKDDRGELWTGTDHATKSAKWTATRADLVFGSHAELRAISEVYSSADAKEKFVKDFISVWTKVMNLDRFDVKTEKETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEX6</accession>
    <name>X0BEX6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="5">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_17889</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 10">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="5"/>
    <dbReference type="EMBL" id="JH658612">
        <property type="protein sequence ID" value="EXK77398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEX6"/>
    <dbReference type="HOGENOM" id="CLU_001103_9_1_1"/>
    <dbReference type="OrthoDB" id="5148578at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF154">
        <property type="entry name" value="RECQ HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="199"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK77398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="432" mass="48357" checksum="459A2C1477C4C58E" modified="2014-05-14" version="1">MMNKSPIVVIMGTGTGKSLCFMLPAASCPGGLTVVRVPLVSFQGDLMDRCQKLKISCAEWRSDRVPGDVSIVFVTPESAMTKRFLDFLESRRVMAKVDRVFADECHTIMEGSLSFRPKLRELGTLALVRVQMIYLTAKLPPADEPAFFSLINARHEDAVMIRARTTRGNVVYSVRSVPASTVEGAVAAIVEQAKVTIVQKLEGYPWLAKIIAYCQRVEATEHLAAKLGCDAYHREVATRDGKAERLKFWMSGTKHEQYGGGRVIVATNALGLGMHIPDIRAVVHVEMPYRMADYAQQSGRAGRDGQRSEAIVIRLDVQGSSRRPRPLVSEHAATDSYISGDVCRRVVLDSVMDGRNDQEGCEEGEELRDFCQCRVDEENRENEGGMVEDREESDMRQRELEVEHARYRAVTLVAQEHQDFLDYKKEARRSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFK6</accession>
    <name>X0BFK6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3295 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658588">
        <property type="protein sequence ID" value="EXK77618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFK6"/>
    <dbReference type="HOGENOM" id="CLU_135141_0_0_1"/>
    <dbReference type="OrthoDB" id="5054775at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031930">
        <property type="term" value="P:mitochondria-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021711">
        <property type="entry name" value="DUF3295"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053043">
        <property type="entry name" value="Ras-cAMP_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28014">
        <property type="entry name" value="NEGATIVE REGULATOR OF RAS-CAMP PATHWAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28014:SF1">
        <property type="entry name" value="NEGATIVE REGULATOR OF RAS-CAMP PATHWAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11702">
        <property type="entry name" value="DUF3295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3295" evidence="2">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="168" mass="18579" checksum="1C09858C0AB91A1A" modified="2014-05-14" version="1">MLAQNDRACTPGNHASQSTSAIPQSPMAIDPSPGASPNDADEAPLMMKGMRGSGVKPIHKVPRSSAQPIRTGPNHIQPQAALSPRTTRRNMLATELTESLRRHLLWERQVKSSTANAVLKRRHTSHDVANLKQYPEKPCMKKSEDVNASSWNRYFSKEATDGYHSKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGD0</accession>
    <name>X0BGD0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658434">
        <property type="protein sequence ID" value="EXK80871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGD0"/>
    <dbReference type="HOGENOM" id="CLU_2996569_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="57" mass="5919" checksum="9D819BB241047323" modified="2014-05-14" version="1">MESLTPTSEQGNLEGTLINGCLKDTGKPTNEWSGKDDDCADEEGGHAAADLLSCGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHV1</accession>
    <name>X0BHV1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658519">
        <property type="protein sequence ID" value="EXK78443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHV1"/>
    <dbReference type="HOGENOM" id="CLU_205454_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="67" mass="7706" checksum="DD6A263D84D7F872" modified="2014-05-14" version="1">MAAYPCSIEFRSCLSIRHIRILNIVFGYITLERENICDDEIGQIQVAINHERTVKQKSSRGDFVPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJ19</accession>
    <name>X0BJ19_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979360">
        <property type="protein sequence ID" value="EXK78464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJ19"/>
    <dbReference type="HOGENOM" id="CLU_585313_0_0_1"/>
    <dbReference type="OrthoDB" id="5410873at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="51525" checksum="838A182FF678F7B8" modified="2014-05-14" version="1">MAALDTLPIELITNVASYLSPRDVKTLSRTNWFMRHAVVGVLFRTLYIPCPLASTRALEVLIHKYQNFISRVHLHVYFQPNIEEKPHDGPMPSVWGAASTDTLKRIVRGDTLSNVSSFVVEFNARDFEHDGWWGETASWLDPNMLGSIVDNEENWDQTLQQEREIIWRAQYNDVMQTISTNQNITNLKISNLIPRNASAWETPEWESFLGRLQVLEIGVFGGDDGDCWHTKAEFADFIGNLPHFVMRHARNVRHLTLEASPDGLFGGASTNYCIPLPLKEDHFLFLHSLTLKNIMIGPELVEFLTSRVDSFEELELYDCMCDGPDWEYGSDRELDPVTWAGLWKAIRESNTRLFKVSVVQSRTPPLMWREGDSKEFETIEDSVEAARIRKMLEEDSHLVLWRYARVDYKYGWVVDLSDDNVKYFEAGEDQREYVKLLKVLEERNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK35</accession>
    <name>X0BK35_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK35"/>
    <dbReference type="eggNOG" id="ENOG502T3NE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024198_0_0_1"/>
    <dbReference type="OrthoDB" id="4763081at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="585" mass="65854" checksum="B4E2815A0B0BF366" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKT3</accession>
    <name>X0BKT3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658468">
        <property type="protein sequence ID" value="EXK79508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKT3"/>
    <dbReference type="HOGENOM" id="CLU_032055_0_0_1"/>
    <dbReference type="OrthoDB" id="3886018at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="14"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="607" mass="69808" checksum="088B5F56BD48C859" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLH3</accession>
    <name>X0BLH3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_16032</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the secreted LysM effector family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658474">
        <property type="protein sequence ID" value="EXK79329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLH3"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF16">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936386" description="LysM domain-containing protein" evidence="5">
        <location>
            <begin position="25"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="221"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="272"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="475"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="434"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="434"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK79329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="525" mass="55978" checksum="828AA239FBEC9DC0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLR5</accession>
    <name>X0BLR5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658472">
        <property type="protein sequence ID" value="EXK79419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLR5"/>
    <dbReference type="HOGENOM" id="CLU_010595_0_0_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="49078" checksum="805E9D2D63B0D17D" modified="2014-05-14" version="1">MVSTPQLLSSSGEQLHKLSQQGGLVRAHVSIDMYIPSWPGTHANDSTDLDTDSSTIGSSENSDDGLDHDIYNPMNDEHVSETEYDDSNDEGFSESDTSSTISLSSTVENYFFLCERQYPNKDTGYSYEPIDPKRTELWEEIYLVCSHVSGDLPKVVISEDCQVWVFTFTLWIAPTDHENKLVLDIGTGTGTSINLTLAPFPGLTDGYSGDWAIDLADDNPGIDVIGIDIVPIQPHWIPPNVKFQIDDCEQEWTFKESSIDYIHARGLNGNVNRTRLTRTVFKTLKPGGVVEFDEMAIDFGACEWDLEMETVLGDWKEFFVDAGEKRRSPFIYVNDTTLQQEMRSAGFEDVKAYTYQIPLGTWSRSEKAGKLGELFLKTLTKDMVGSVLRIATEDLEWSEQRAQVFAATVRNKIHLDCNKCKIYTTRTIVFGKKPGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMH3</accession>
    <name>X0BMH3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">P-type Cu(+) transporter</fullName>
            <ecNumber evidence="3">7.2.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Cu(2+)-ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">FOQG_12720</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="17">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.8" evidence="3"/>
    <dbReference type="EMBL" id="JH658407">
        <property type="protein sequence ID" value="EXK83051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMH3"/>
    <dbReference type="eggNOG" id="KOG0207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_0_1_1"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140581">
        <property type="term" value="F:P-type monovalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000001">
        <property type="entry name" value="ATPase copper transporting beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00003">
        <property type="entry name" value="copper ion binding protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF8">
        <property type="entry name" value="P-TYPE CU(+) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00942">
        <property type="entry name" value="CUATPASEI"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-0187">Copper transport</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="598"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="640"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="993"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1021"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="31"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="133"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="215"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00080126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EXK83051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1099" mass="117037" checksum="94E84DC5A7D6BAFE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BN39</accession>
    <name>X0BN39_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin homeostasis protein lub1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12424</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658404">
        <property type="protein sequence ID" value="EXK83241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BN39"/>
    <dbReference type="eggNOG" id="KOG0301">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011791_2_0_1"/>
    <dbReference type="OrthoDB" id="10265988at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.870:FF:000003">
        <property type="entry name" value="Polyubiquitin binding (Doa1 Ufd3) protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000236">
        <property type="entry name" value="Polyubiquitin binding protein (Doa1/Ufd3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.870">
        <property type="entry name" value="PFU (PLAA family ubiquitin binding), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015155">
        <property type="entry name" value="PFU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038122">
        <property type="entry name" value="PFU_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF0">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09070">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51394">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="210"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="238"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="PFU" evidence="7">
        <location>
            <begin position="377"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="8">
        <location>
            <begin position="495"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="466"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK83241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="770" mass="83173" checksum="F8C0F0848D84E2DE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP71</accession>
    <name>X0BP71_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK83990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP71"/>
    <dbReference type="HOGENOM" id="CLU_104705_0_0_1"/>
    <dbReference type="OrthoDB" id="5090716at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="231" mass="26705" checksum="5140F7E79FF37A36" modified="2014-05-14" version="1">MSNKTSNETSMIAEKPPKAPEEKPSEKSVEADNMSAKATTGHGVKGHEKAAPEAKEVRYASYYGDGSGLPLRPGMGPPMTEEEFQESWKKSKARAERLWRMSDEEFYAQFPECNAVKDCYFTEEEAEELLEGEDKDKPRYAHRYGDGSGLPLRPGMGPPRTEKEFEEEYKKIEAEEDKIFNMSEEEFNVEFPEYSKFTKDMPEYFCTEHEAWKIMEGYDEDEDRNHSEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP85</accession>
    <name>X0BP85_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_11735</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP85"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF52">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="42"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="507"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="525"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK84005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="535" mass="59645" checksum="47F3CB47FC30B0B8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPW0</accession>
    <name>X0BPW0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Questionable protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPW0"/>
    <dbReference type="eggNOG" id="ENOG502TH59">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137522_0_0_1"/>
    <dbReference type="OrthoDB" id="2910287at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936591" description="Questionable protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="14854" checksum="13D0B0FB877BB857" modified="2014-05-14" version="1">MKFFTVIATIISAVSISAVPILKERAVGGVLICTGANSTGTCTHEVYTLNKCHQLSEPFLRNVTTFAPDGEYFNCYPRTTGCNDTCMSPTGCTIGPIDFDYKFKFNFTRVGWPKLFNSFDCSLKKTTKGENMFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR97</accession>
    <name>X0BR97_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_14534</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK81009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR97"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF48">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G01000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="63"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK81009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="511" mass="56298" checksum="A201C5A9561DD51E" modified="2014-05-14" version="1">MTARDSDAERGNGKEPWSKEFEHADAHDAAARGHLATDEHGNPIATFDAEAEKKLRRKLDWYIMPSVTILYLMCFVDRANIGNARLAGLEEDLGLAGYDYNLLLTVFYISYIVFELPLNMVCKWIGPGWFIPATSVAFGVASLGTAFVHTMGQACAVRFILGIFEAGMLPGIAYYLSRWYRRSELAFRLAIYVAMGSFGGAFGGLLASGILKLDSFGSLTRWRMIFAIEGICTIGLALIAFFTMTDRPSTARWLSEEEKDLAIARIKSERVGATEVLEKFSWKLARRGISSPVTIGTSTIFLFTNITVQGLAFFAPTIVRTIYPNHSVVQQQLRTVPPYIVGTFCTVTISFLSTRIDKRNIFINLSQLPVIAGYIMFLSTTNPYVRYAGTFLICAGTFANGALSNAQVSANLVSDTARASGIGLNVMLGNIGGLISTWCFLPFDGPNYPIGNGLNLGACSSIFLLTIVLQVYMTWDNRRRAAIEVGQALAGKTDAEIRVMDWKHPGFMWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSB9</accession>
    <name>X0BSB9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11278</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSB9"/>
    <dbReference type="eggNOG" id="ENOG502S05E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019364_0_0_1"/>
    <dbReference type="OrthoDB" id="2152029at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="4">
        <location>
            <begin position="130"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="382" mass="42687" checksum="C6A46438E06DF915" modified="2014-05-14" version="1">MAVLSTLKTAFGYTYAFIITPWLLSRFLFDISLCLVPWLRPNRKWTLNQAVRVRVVRLLLLYWSLTKSGDKMRFDQGKEKNRFEVVAPRSPKLYRGICSDYTVQPAQLGMTWTPARPPPAGIVHPGMVVVLHFHGGGFVIGNGRDEDTGFTAKTLIKHMGATHVCSPNYRLSSSKNGQFPAPLQDALTAYLHLIKTRGIPADQIIFSGDSAGANLALALVRYIHEYGQIDEVPFPRAMALWSPWTDVAGALEQDATQSPNYKTDYLNMHFARWGATTVSGFGAIDPSSPYLSPLRHPFQIEKPFPVYVNAGGGEVLCDDITNFVARYKKNGWPMYLDISEGCPHDIILLGDRIDFTAEAEKAAEHARRFLNHRAGLNLRSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTH5</accession>
    <name>X0BTH5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTH5"/>
    <dbReference type="HOGENOM" id="CLU_107714_1_0_1"/>
    <dbReference type="OrthoDB" id="3468019at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="16998" checksum="40AD0B350AEAD3E7" modified="2014-05-14" version="1">MSSKGQPVLDTIWLSEGVSPEIKILISSFFELADSKDPEAGRQLATSVFTKDAVFVSASGTFQGYQEISKCRDGAWNLVESRQHRVQKAFFSTTDGLELCLLASVKIEFKNGNLIESPFACHVQLEMTGSEEGSLRIRYLQVFADTTPLRAAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BU34</accession>
    <name>X0BU34_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BU34"/>
    <dbReference type="HOGENOM" id="CLU_603514_0_0_1"/>
    <dbReference type="OrthoDB" id="5088000at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="482" mass="54948" checksum="3BCE1E8B29B0960E" modified="2014-05-14" version="1">MELACGCSLGQYLAMFATPGSISDLVDIRRNLRQRSRQRGATSYQASLEQFRSRFMTRLRISDKDLIDRNDVVHQKGLIEMAHEYLCVCKNGSLYWPSTSDDGSLRYSRDRYEIYTNIVWFFLRRNLKDIGKRLRSTRSRTTTAANNGRRSRNPLNILGSESPTPSPPDHDSPNYAAAANEDGDSSSSSESPQSSQTPRQDEAMNNRRPIPYGRAYSPDELAEEGINESLQPIPDAQPRRVSRMQDLQDNLRHIGPDPRPNMGVDHRERGNNPSAHTTSTGTQTGFETDEYRDRDPNAPPPSSMNSNNASQQSQQAYHNNNQPRPRRPRDSIEYGQRSPSPPYGVPRSPSPEPKPNIDLIFSYDVLPGLNLRLAHGEEIFSFPREQVFRLLGWQHDFDWLLISLETPGALFPERIARDDNREFRKVMARFEQIACAMKRDYAEIGRDAVIEVAFVPECKGHSRTVLQDGWRKRLEESRGIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVB1</accession>
    <name>X0BVB1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_10166</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_244430_0_0_1"/>
    <dbReference type="OrthoDB" id="366390at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="5">
        <location>
            <begin position="224"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="675"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="746"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="846"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="879"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1365"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="915"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="915"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="959"/>
            <end position="968"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK86120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1597" mass="176809" checksum="F8B50D7DF7A53CB4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVR5</accession>
    <name>X0BVR5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK85986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVR5"/>
    <dbReference type="HOGENOM" id="CLU_002341_2_0_1"/>
    <dbReference type="OrthoDB" id="443402at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056693">
        <property type="entry name" value="DUF7791"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029498">
        <property type="entry name" value="HeLo_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25053">
        <property type="entry name" value="DUF7791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14479">
        <property type="entry name" value="HeLo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="290"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="943" mass="106959" checksum="E6F96F6A4EC1A545" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVY3</accession>
    <name>X0BVY3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVY3"/>
    <dbReference type="HOGENOM" id="CLU_058857_0_0_1"/>
    <dbReference type="OrthoDB" id="4191440at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="421" mass="48629" checksum="2EC405ECDFCDC6BD" modified="2014-05-14" version="1">MDTLHKAFFSIFMITWGILMIVNIASICGRTARTFGRLRFWSFIPLWLYGPLVVLNPWWRLGHLDRGHQFLGIWLTLWPILSSIIAASHESRGSWDSSQRSRGCFYILCVDWAIILFSIVEVCRNPIPTGSKDWTFGASLGKIMTMFTIILLAGQDFLIFPIAAFPRFISLPAIILRRRFLPIQYKPVKRWPHDINLLSSQKPPGQERSLAIMLQSDNIAERLASHLHYDDLVNLSFTSKLMRTGVFYPSMDPTSRHDRIESLCIASCLKGKKSECWSCERVICDACKAPKQRIRSSRIKDHFAHCYAVCTMCYLISAPGGAAPFNAKWNMQDLEMQHVNCCTFREPQWEDGGRYLCRYCIKLDGEKLTDMKEKRDEFYLSRTLPRNVDCAICMWPIGKGSTRWWFCGKGRHECHWAGHHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW61</accession>
    <name>X0BW61_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_10187</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW61"/>
    <dbReference type="eggNOG" id="ENOG502SHD0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015464_0_0_1"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="213"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK86141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="645" mass="73519" checksum="5F7800DD537402B1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX15</accession>
    <name>X0BX15_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX15"/>
    <dbReference type="eggNOG" id="ENOG502QQXH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_4_3_1"/>
    <dbReference type="OrthoDB" id="2129491at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF12">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="42"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="541" mass="60670" checksum="2E281F0373120295" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXD6</accession>
    <name>X0BXD6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_12118</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXD6"/>
    <dbReference type="eggNOG" id="KOG1430">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045580_1_0_1"/>
    <dbReference type="OrthoDB" id="10058185at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000252">
        <property type="term" value="F:3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF447">
        <property type="entry name" value="HYDROXYSTEROID DEHYDROGENASE_ISOMERASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06450)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="4">
        <location>
            <begin position="77"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK83598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="487" mass="53832" checksum="7B9952B921C99233" modified="2014-05-14" version="1">MAAKLFLVFLGLGVFFVALGLYLRRINRLLKETPPQVGQLRGKPWTPKLLRHTYEVLEKSPINFDGRLPPKLNRRYIVTGGNGLVGGYIVLQLLARGTLPRCIRIVDVRQTERDDLREGLAARVDYVQADITSKAAVGDAFSKPWDPKIASLPLTVFHTAAVIIPGARSKYLYKFTESVNVQGTKNVLAASRAVGADIFSSTSSASISIRPVEAFVAPWVEPKHYWQVMDTQDFDKPLREHEEYFANYAVSKAIAERLVCAENEPSFRTGCIRPGNGIYGHPSDNPIGNLLARDVNQTWVPHIVQNFVHGANVAVAHLYHEAALAKENCTQAGKPFVVTDVGPPITFGDVYTAVEVLSIHPFRNVIVPPLIILLMTHIVEWFILLPHRLPFLKGILPEVKGDLRTVQPGLITICTHLVASDTEARQPISEGGLGYKGLFTTLEGVVSVIMDWNQEHAGEQTREGKKIYQGSLRLAEMLEEAGSSVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXE3</accession>
    <name>X0BXE3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXE3"/>
    <dbReference type="eggNOG" id="ENOG502T5BF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1304895_0_0_1"/>
    <dbReference type="OrthoDB" id="5101420at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="211" mass="24370" checksum="641F7821F2766744" modified="2014-05-14" version="1">MSRRQDHHQRHYGQTYNTESSRNWSEEAVRGSWDSNYQRTTSANTSPRDQSQAWRRPSPQAYDRRQTMVNQWLGQQYSHDPSNVMDAVSDLTTPTTSPAFSDSPTFPSRTQEAPPYQTHAVANDFLAPPLRTSIPHRPHDGHYHNAPPASSRGSTSYRLDNRSVDYRHMEPRSAEQDLRGVGSFADNDRSRREVKYKPLSNWFGLWLPPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXN8</accession>
    <name>X0BXN8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658404">
        <property type="protein sequence ID" value="EXK83264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXN8"/>
    <dbReference type="eggNOG" id="ENOG502TDJF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1586520_0_0_1"/>
    <dbReference type="OrthoDB" id="5092768at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="168" mass="18688" checksum="6100D3023AAAB649" modified="2014-05-14" version="1">MSSQNSSSSSKDTSKKESSELKKLHFVASFEHQKLLEDVSNKAYDLGVKAGREQANPPDDETQALILSLTDRNDELEKQVKDLATDALLNLAKDVRNNVTSAHRAVSSATHADGLTLNYYRILRESCSELSELEDKCKERVDKISRAANKRAGGALKREDLPKRPFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ09</accession>
    <name>X0BZ09_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_12070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ09"/>
    <dbReference type="eggNOG" id="ENOG502S098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006016_0_1_1"/>
    <dbReference type="OrthoDB" id="5093543at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07491">
        <property type="entry name" value="Peptidases_S8_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="193"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="702"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="259"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="261"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK83734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1024" mass="115037" checksum="BFA14B7DEB794941" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZL4</accession>
    <name>X0BZL4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Homoserine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11619</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZL4"/>
    <dbReference type="eggNOG" id="ENOG502QVPA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028760_2_0_1"/>
    <dbReference type="OrthoDB" id="9972683at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005757">
        <property type="entry name" value="PRK07581.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF15">
        <property type="entry name" value="HOMOSERINE ACETYLTRANSFERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="58"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="350" mass="39210" checksum="5D54E3173DE7103E" modified="2014-05-14" version="1">MDVKTFSLGDFELQNGKVLPNAVIAYKTFGEAELPAVLYPSWFSGAISDNEWLIGKDKTLDPERYYIIITALFGNGQSTSPSNSDISPFPDVSFYDNVRAQHQLMGHLGVKHLRAVLGWSMGAAQTFQWATQYPDFMDICVPFCGSAKTSLHNQVFLEGVKSALLAAKGCTSAGSIQGRVETTDGTWTEKEREVGLKAFGRGYAGWGFSQAFYRHELFKKHYGAADLEEFMKNFWEKWALSKDPENLLVMLQTWQAGDVSKQEAYGGDFEKAMKGIKARILVLPSKTDLYFPPEDSEYEVKCMGDNASLDVYPSIWGHWAGGPPGNMEDVKWLDERLRKIFDEAPRRDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZP9</accession>
    <name>X0BZP9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11436</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZP9"/>
    <dbReference type="eggNOG" id="ENOG502SA1Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092860_0_0_1"/>
    <dbReference type="OrthoDB" id="5329332at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="262" mass="29069" checksum="3632215DE6309BF9" modified="2014-05-14" version="1">MVYLSPSQHGDCLKCYLATPFTDDELKAFKAAFELGACSKFAPLMQLKILHAPEDYLGKSHQYIRAKETEAGNKDPFIVVDDEAKSRGAVWYIDQFAEEDQVEDGEAESTDVVFKILTQTEALAVSHINYAIANSSIGEDLDNCAVDLPLTNDFHQPDLNDCGGLDFEQQQWEQDAWVIAEPGEFEESTNPELLNNSSPPPEKVARLKDDVAESIGLVSSWTIPSNAEPIDLEDGTKKEFPEGSVVLQQKCNPEFPWPADLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1E0</accession>
    <name>X0C1E0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MUC1 Extracellular alpha-1,4-glucan glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1E0"/>
    <dbReference type="eggNOG" id="ENOG502QUB2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005577_0_0_1"/>
    <dbReference type="OrthoDB" id="5559380at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051293">
        <property type="term" value="P:establishment of spindle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031578">
        <property type="term" value="P:mitotic spindle orientation checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030473">
        <property type="term" value="P:nuclear migration along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013889">
        <property type="entry name" value="Karyogamy_KAR9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37271">
        <property type="entry name" value="KARYOGAMY PROTEIN KAR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37271:SF1">
        <property type="entry name" value="KARYOGAMY PROTEIN KAR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08580">
        <property type="entry name" value="KAR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="795"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="447"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="638"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="755"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="809"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="857"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="940"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1003"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1033"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1075"/>
            <end position="1085"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1085" mass="117487" checksum="B14D5C78681E3584" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1H4</accession>
    <name>X0C1H4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979470">
        <property type="protein sequence ID" value="EXK76637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1H4"/>
    <dbReference type="HOGENOM" id="CLU_3175424_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="47" mass="5375" checksum="40D51323A4B56D6C" modified="2014-05-14" version="1">MLTIRYSNFQLYVSPRITFGGGIFNTTRTPETMDSSRPKAYNAQSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2Y8</accession>
    <name>X0C2Y8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2Y8"/>
    <dbReference type="eggNOG" id="ENOG502TBCQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1214797_0_0_1"/>
    <dbReference type="OrthoDB" id="5091088at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937337" evidence="1">
        <location>
            <begin position="18"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="254" mass="26462" checksum="E92797EFFEEBD76B" modified="2014-05-14" version="1">MRFALLWSLLAADAAVASVCKPRQSSGSSTAATADIETKTTTSVELSTSIATSTVEDVTITEAATAVDTSTETAASTLTVAETTTSDIAGPLETFILAAKVEGTVSEELSGADRDGSPVVWPTPRFIASGPLIISIDSTTSYLQTSGGFYLCVAYGDGTTPNGVKLCSAESLNNPAFGALTCEQTEDRKIACEAQAGQCISDGENNVCSQLPGTYDQFYYYRGLFNGVYLGIGSAVNTDESQHPVELKARRSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C342</accession>
    <name>X0C342_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Delta(14)-sterol reductase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">C-14 sterol reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Sterol C14-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_08376</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C342"/>
    <dbReference type="SMR" id="X0C342"/>
    <dbReference type="eggNOG" id="KOG1435">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015631_0_3_1"/>
    <dbReference type="OrthoDB" id="10262235at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050613">
        <property type="term" value="F:Delta14-sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018083">
        <property type="entry name" value="Sterol_reductase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF52">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE TM7SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01017">
        <property type="entry name" value="STEROL_REDUCT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01018">
        <property type="entry name" value="STEROL_REDUCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12 13" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU369120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK88581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="485" mass="54817" checksum="127F0E744C325A49" modified="2014-05-14" version="1">MAVKDKQPASEEQHGYEFFGPPGAFVISFFLPILVYVFNFVCNDISGCPAPSLLHPKTLSLDALKHEVGWPSNGVAGLVSWKGTAAVIGYNVLSLILYRVLPAVEVEGTELRSGGKLKYRFNTLYSSTFTLAVLAAGTAAQGAEFPVWTFMSENFIQILSANIIYSYLVSTFVYVRSFSVKPGNKENRELAAGGHSGNMLYDWFIGRELNPRISIPLIGEVDIKEFLELRPGMMGWIIMNCSWCAQQYRNYGFVTDSSILITAVQALYVFDSWWNEPAILTTMDITTDGFGMMLAFGDIVWVPYVYSLQTRYLSVHPVSLGPLGLAGMLGLIGLGFYIFRSANNEKNRFRTNPDDPRISHLKYIQTQKGSKLLTTGWWGIARHINYLGDWIQSWPYCLPTGIAGYQILSAGTHAEGAWVMRDGREVIQGEAKGWGMLITYFYILYFAILLVHRERRDDDKCHRKYGKDWEEYRKIVRYRIIPGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C348</accession>
    <name>X0C348_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sulfate transporter family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_18102</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658633">
        <property type="protein sequence ID" value="EXK77182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_233739_0_0_1"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034490">
        <property type="term" value="P:basic amino acid transmembrane import into vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000012">
        <property type="entry name" value="Sulfate transporter family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029526">
        <property type="entry name" value="PGBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF4">
        <property type="entry name" value="AFR304WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13843">
        <property type="entry name" value="DDE_Tnp_1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1219"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1251"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1309"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1343"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1385"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1415"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1475"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1553"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1584"/>
            <end position="1600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1612"/>
            <end position="1641"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="11">
        <location>
            <begin position="1679"/>
            <end position="1789"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="1896"/>
            <end position="1993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="876"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="917"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1049"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1109"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1051"/>
            <end position="1060"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK77182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2010" mass="226533" checksum="ED75E2904ED8FF2C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3E4</accession>
    <name>X0C3E4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_17997</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the secreted LysM effector family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979398">
        <property type="protein sequence ID" value="EXK77297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3E4"/>
    <dbReference type="HOGENOM" id="CLU_010591_8_2_1"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936152" description="LysM domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="39"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="191"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="370"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="452"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="103"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK77297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="502" mass="55483" checksum="E70F9A928DA4BFCA" modified="2014-05-14" version="1">MRSIALPLLFCWTLLPAVLAQDSKPGAPVHPGQPSNCIAWHTVKQGDDCETVPKKYYITKEEFLAWNTAVSKDCLTNFWLKYAYCVRIDGTSAIYTSAQSTETSKTTVTTKSNDPTSPTSKTTSTKDISSTISTSSKPASGTTSESVVTTSVNTTYSVRNSVSTWNITTPTTDVTWPPKATQSGQPKDCNKWHLVRGRQSCQDVLNIHSSLMKKENFFKWNPEVHEDCSGLFVGYWYCVGVKLNATNNLEWETSTPPFTPPPEPTSYTPTKLTPANSDFTPTPSHGPMPTDCIHYHQAEADESCRDVLKTYSYLSKDQFFKYNPVLKNNCDGLWKDNWYCVGVKSDLLMPPTVTTTPSDIPSESPKDCKAWYYTTGGESCEQLANMFGTFSADEFISMNSAVFEDCSDIEDNTWYCVAGPDTPTTRTADLTTPTQPATAMPTQSNVASDCKEYWLVSKKDTCRSIRRANSISLEKLLAWNPALGSKCSGLKPDSYVCVSAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3I6</accession>
    <name>X0C3I6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08216</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3I6"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_1"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000173">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier protein] reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF127">
        <property type="entry name" value="3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK88980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="29248" checksum="644C18650BB61718" modified="2014-05-14" version="1">MTLRLQTIDNNLKGRLALVTGSSGGIGSAVARAFAAQGCDVGLHYSSSKEKADKLAQELSETHPSQLFVPVHADLSQRESTRALVSSLLSQDVVSSKHKAVSILVANAGLGRRIRDVAEIGEDDWDEMMEVNSRSQFVVTKACLSGMRQQGWGRIILVGSIAARGSGLNGCHYAASKGALTSMGQNLATLLAPEGVTVNIVSPAMIGSTGMIPPPISETWDKGCDLEELKKTDPGLAIAASIPVHRLGSPNEVCEAIIMLARNGYMTGQDILLSGGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3N5</accession>
    <name>X0C3N5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3N5"/>
    <dbReference type="HOGENOM" id="CLU_028684_0_0_1"/>
    <dbReference type="OrthoDB" id="5986190at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="104"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="639" mass="71562" checksum="9CD08F9AA66B8B14" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4H0</accession>
    <name>X0C4H0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10456</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4H0"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_4_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF213">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936942" evidence="3">
        <location>
            <begin position="20"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="673" mass="72536" checksum="AE7A28C4B73915CC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5R1</accession>
    <name>X0C5R1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5R1"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_3_2_1"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF1">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="8"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK86533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="422" mass="47181" checksum="B0957F60F4F408C9" modified="2014-05-14" version="1">MIPTEDQPVLIIGAGISGLLLAQSLSRHGIPFRVFERDTDLETRGVGWGLTLLWTLPALKALLPKPLFDRLPEAYVDREAVTQGLSSSFPFFDLSTGELKASVPKAPEAERVRVTRQGLRALLATGIDIEWSKAVTGVVSTDDSVTASFEDGSSVTGSLLVACDGSHSRVRRSLFPEWKLQDIPVRMLGIKMELSPSQIKPIRDLDPYFFHSTNSRNDTFIYFSVLDAPGNQADTNRPYIGQLCVSWPYREGFLNRPSPIEIPETPEEKYKLVQELTLTWAECFRPLASAVSLDSEMKGLKIQDLTPPRDFQTAGRAVLMGDSLHTMAMYRGEGANHVIFDVKDFVERVVPALSGDGDLRSALDEYERAVITRTRPAVLASRRACLDAHDWKRISKMSPLLTKRMPYIEFEETEEAEVMHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7Q6</accession>
    <name>X0C7Q6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979353">
        <property type="protein sequence ID" value="EXK78742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7Q6"/>
    <dbReference type="eggNOG" id="ENOG502QUMI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017444_2_0_1"/>
    <dbReference type="OrthoDB" id="1911848at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056002">
        <property type="entry name" value="DUF7580"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542:SF3">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24476">
        <property type="entry name" value="DUF7580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="211"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="550" mass="62347" checksum="791EA5E68E676453" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7X0</accession>
    <name>X0C7X0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosylphosphatidylinositol anchor biosynthesis protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_06780</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7X0"/>
    <dbReference type="eggNOG" id="KOG3144">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069429_0_0_1"/>
    <dbReference type="OrthoDB" id="17366at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009580">
        <property type="entry name" value="GPI_biosynthesis_protein_Pig-F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06699">
        <property type="entry name" value="PIG-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK90525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="257" mass="27226" checksum="ED2DB9E7F6CB32E5" modified="2014-05-14" version="1">MPLVDPVTMSTTLVKSGPAAQQPATKAAVPAIPLVNSPAALPASVAHQLLLAGLFYWRFDALVADPVSTLQTGLPVVAAIQAVYLILSLPPAGSSGSSKKPRPGEKRKSDGREAKAIPTAVISLLLALILTPALHLLLVLFGAPFLTHVPHTFLCCAHIAVLAIYPVFYVRGSDPVPLQAVVGVSAPFDQTFGGFIGTVVGAWLGAVPIPLDWDREWQKWPVTIVVGAYIGYIVGSQILGTVFFGKRWEVTPEIKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C831</accession>
    <name>X0C831_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_07098</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C831"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_1_2_1"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF228">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="GH18" evidence="12">
        <location>
            <begin position="5"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK90271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="349" mass="38369" checksum="0708C0AFFFF098CD" modified="2014-05-14" version="1">MSNQYINAVYYPSWRCYKERPPSCLDTASITHIFYAFVGVNEDGTLRSIDDWGDNNKVVDGEKGCLAALRKLKGQHPHIKTLVSIGGGSSSKEFPALAASKAARQTFARQIKEFCDAHHFDGVDVDWEHPQTPEAGKNYVLYLQAIRETMPAPKYLLTSALPTGEYCLKHLNLPVVAQLLDFLNLMGYDFTGGWTDVCGHHAQLLPPSNNLNEVYPTLRKSCQRGVDYLTSQGFPNRKIILGIPAYARYFGQARGPGHPFKGSGEIDYCDLPDEWVAGAKVEESIAAASFVDTKGDKGFVSFDVPSTVCVKARYAKAMCLGGLFYWTGAGDRAGPESLVAAGWKTLHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8P9</accession>
    <name>X0C8P9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8P9"/>
    <dbReference type="eggNOG" id="ENOG502STPP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029371_1_0_1"/>
    <dbReference type="OrthoDB" id="5296720at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="7"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="446" mass="51106" checksum="7F9F104F66BEF216" modified="2014-05-14" version="1">MASLNMQNLPNELVAHILSFLDSESDLQRRIYLDPAKLNRPVSSGPNTPLKNASLVCRLWRSSVIKILFRYVVWPFWRFYKPVAQDVASQIEVLNFIRRNNLSSSVENFTILIDLPLGSGQNRYPDGQFWGVLPPVSHQPETPMSWNLLWSVLNQEDRDAEGSDTRTEEDRAQCFWDNNWLWHTIFDVIDPSRITMISSIDILASLLSRTVDLSSHWAFNSTYYVLSLSRPSRSIAESKRVQILPSHIPGPTNRIPCDLFHIRDWSSVLVNEGSFAPVYSTYEFFHYSAATLLPAIFDSSDPSFDVLCANLHSLSYIATFPLSHHISDHLIPNCPPVEHLYVQLMPKNRDFWESSSLSRVNLSDLWLECDTSYALLVRQMLETVPQPGWQKLKVFETGDTPAEGVWKMNTYDDHINGSNGWREESEGVFVKDDIESSDEQTMVEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8S9</accession>
    <name>X0C8S9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">NADH-ubiquinone oxidoreductase 24 kDa subunit, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_06789</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="9">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8S9"/>
    <dbReference type="eggNOG" id="KOG3196">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054362_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902494">
        <property type="term" value="C:catalytic complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098796">
        <property type="term" value="C:membrane protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000022">
        <property type="entry name" value="NADH dehydrogenase flavoprotein 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1590:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01958">
        <property type="entry name" value="nuoE_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005725">
        <property type="entry name" value="PRK07539.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371:SF3">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01257">
        <property type="entry name" value="2Fe-2S_thioredx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 9" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="11" id="KW-0830">Ubiquinone</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="218"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK90541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="260" mass="28622" checksum="0CA70D1C8FC93BBB" modified="2014-05-14" version="1">MASKLTPLIRSAIRPVCRAARPQSRAAFSLTASRRSDTLMVHRNTEDNNPDIPFKFNEKNQTVIAEILKRYPPQYKKAAVMPLLDLGQRQHGFTSISVMNEVARLLEMPPMRVYEVASFYTMYNRTPVGKYFVQICTTTPCQLGGCGSDVIVKAIKEELGIEQGQTTADGLFTILEVECLGACVNAPMIQINDDYYEDLTPASVKDLLKSLRAQATASDPSTVNVPKPGPLSSRDTCENSAGQTSLNAEPWGTETTRADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8W0</accession>
    <name>X0C8W0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_06807</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8W0"/>
    <dbReference type="OrthoDB" id="38125at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.140.10:FF:000001">
        <property type="entry name" value="SPE3p Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000013">
        <property type="entry name" value="Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002010">
        <property type="entry name" value="PRK00811.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="5">
        <location>
            <begin position="115"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK90571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="396" mass="44591" checksum="4B6C38C614137124" modified="2014-05-14" version="1">MTVPSPVSVSVWAASNFLPAKAMAVSPLILTTGSSCIRRRGRGYLYNRVHQLLQKQWMHLFKKSRLPPFSSPPRNITTSTFGSSLAFTSRRTFSSFYSSNNKMSSEEITHPTIKDGWFREISDMWPGHAMTLRVEKVLVHEKSKYQDVLIFKSTDFGNVLVLDNVIQCTERDEFSYQEMIAHLALNSHPNPKKVLVIGGGDGGVLREIVKHDCVEEATLCDIDEAVVRLSKEHLPSMACGFDHPKSKTHIGDGFKFLNDYKNEFDVIITDSSDPDGPAEALFQKSYFQLLHDALREGGVITTQGSESPWLHLPLITRLKKDCQAIFPVAEYAYTTIPTYPSGQIGFMVCSKDPKADVKTPLRSWTKEEEDAKCRYYSAEIHKASFVLPKFAQKALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C937</accession>
    <name>X0C937_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sorbose reductase SOU1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09053</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C937"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="31743" checksum="C58B88E086F6F3E6" modified="2014-05-14" version="1">MAPGATELPDRDALTARAVPSMVLSDGSTSSLTAPPSNKIAIDPATGAKERFAVRGNFIVTGGTGTLGLASCNALLEHGLEGLAILDVNPAQAKQEVASLQARFPHTRITTMKVDVTDERAVQDAVDETVASLGSVDGLVCFVGVVGCVETLEMSVSQWRKIIDINTTGSFICAQAVARQMVKQGTGGSITFTSSISAHRVNYPQPQAAYNVSKAALLTLKNCLAAEWARYGIRTNTISPGYMDTILNDGDGISGHRKIWAERNPSGRMGAPCELTGAVLLLASSAGTYMNGTDIVVDGGAIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C949</accession>
    <name>X0C949_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658477">
        <property type="protein sequence ID" value="EXK79192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C949"/>
    <dbReference type="HOGENOM" id="CLU_095770_2_0_1"/>
    <dbReference type="OrthoDB" id="2679825at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054208">
        <property type="entry name" value="DUF6914"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21858">
        <property type="entry name" value="DUF6914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="182" mass="20581" checksum="EB3D7294C13D81DC" modified="2014-05-14" version="1">MPSNKDRLYVGLYARGGTAKMPGGEDRYHWALLVAPKVEDSETRGKRFHAKERIYSGMQSVWEFSEQETGTSSTLMILVRIQVAKVLNMKSLEAILRSVPVRGEQRGWNCVEWVREALAALQNDNKALGTSVLDWATVRDTAMWYVEQKAMQHRFDGQAAPGQFDTSRVSTYDLLEGNELVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9H1</accession>
    <name>X0C9H1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Period circadian protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9H1"/>
    <dbReference type="HOGENOM" id="CLU_037529_2_0_1"/>
    <dbReference type="OrthoDB" id="2590867at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39606:SF1">
        <property type="entry name" value="CELL SURFACE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39606">
        <property type="entry name" value="SURFACE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="35063" checksum="E657B9C4A21396E0" modified="2014-05-14" version="1">MSGLINKVKDAIHSDKDKSHEQPTGTHGPHSSRAANAADPRIDSDRDHRANPGTTTGHHTTTGGLGSTGTTGTHSSGLPEGSVGPHSSRAANAADPRVDSDLDSSRRTGATGSHGLSGTTGTTGGLTGGSNYSENMPGHTTGGLGHTGGMGRSENLPEGSVGPHSSRVANAADPRVDSDLDSSRRTGGIGATGGMGGNTYDHTTTGTSGFSSHGAGAHGPTGTHTSGLGGTGSTGTYGSTGTGTGAGLGGAGSGYGTGPGPAPNTAGPHKSDALNKADPRVDSDLDGSKTVGKEKTFQQSNNNFAGRDPTDATQVPPSVLQKHVPTEIAHDDPHSDHSRRHSSTHQETHRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAY3</accession>
    <name>X0CAY3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_15618</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658458">
        <property type="protein sequence ID" value="EXK79832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAY3"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF3">
        <property type="entry name" value="HEXOSE TRANSPORTER PROTEIN (AFU_ORTHOLOGUE AFUA_8G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="41"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK79832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="516" mass="56698" checksum="17F63A756FBDB278" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCC1</accession>
    <name>X0CCC1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Chitin binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_08309</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCC1"/>
    <dbReference type="eggNOG" id="ENOG502QRIP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021264_11_3_1"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936921" description="Chitin binding protein" evidence="10">
        <location>
            <begin position="22"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="41"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="12">
        <location>
            <begin position="118"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="372"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="428"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="343"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="391"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="447"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK88489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="50371" checksum="616AA3D029249655" modified="2014-05-14" version="1">MKTSLPVTLASLLLHAGTVLSGPVFAADDLLSLRDSKLRKRAECGLGIGSCNPGSCCSESGFCGTTGDFCGGSACQLEYSDSCDTFFGPRGSSTEGISRPQLGNVPYGTVITTCTTPGVIALTFDDGPLDYTNDLLDLLDERDVQATFFVAGNNRAKGHIDDSSNPWPAVMRRMFSAGHHIASHTWTHRNLNEVNSTIRRSEIIYNEMAFRNLFGWIPTYMRAPYLECNAASGCLDEMSELGYHVVDQNIDTKDYENDNPALIQISKDRYSSGVSSNSDNNQYIVLAHDVHDQTVHNLTAFMIDTAQDRGYRLVTVGECLGDPQENWYRTVSRGRDVTSTESATPTQTVPPTNVSVTTSTATATGGLVISPNQQCGGNTGYTCQGSAFGSCCSWYGYCGSSESYCGTGCDADFGSCTPSGSDIHDTTNGLCGPGVRASCGNYGDKTCCSQYGFCGNSAAHCGAGCQGGFGECN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCH9</accession>
    <name>X0CCH9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peroxisomal-coenzyme A synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_08183</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCH9"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_0_1"/>
    <dbReference type="OrthoDB" id="3633556at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05926">
        <property type="entry name" value="FACL_fum10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045310">
        <property type="entry name" value="Pcs60-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF5">
        <property type="entry name" value="MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="26"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="6">
        <location>
            <begin position="422"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK88923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="56236" checksum="2091F318EA2CDB31" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEE7</accession>
    <name>X0CEE7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7704 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEE7"/>
    <dbReference type="eggNOG" id="ENOG502SV8Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112091_1_1_1"/>
    <dbReference type="OrthoDB" id="3587182at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056121">
        <property type="entry name" value="DUF7704"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019:SF1">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24803">
        <property type="entry name" value="DUF7704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7704" evidence="2">
        <location>
            <begin position="6"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="152" mass="17098" checksum="765B22E7E3D0A2A5" modified="2014-05-14" version="1">MSELNVNNFYRIWFTWVDPLTVLPTVYALIFTPEFILDGLIPLSMSAYNPDQAFLFHQLAALYAFVAIMLAVLLRVSSNIKVWRVVIGGVLLIDIAILLSVFVSMKQQGRSEFSMFRWQDWGNYLFTGWVAVVRALFLAGVGVGGVNKGKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-05-29" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF27</accession>
    <name>X0CF27_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mediator of RNA polymerase II transcription subunit 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_05816</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Mediator complex subunit 21 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF27"/>
    <dbReference type="eggNOG" id="KOG1510">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094271_1_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.10">
        <property type="entry name" value="Mediator complex, subunit Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021384">
        <property type="entry name" value="Mediator_Med21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381:SF0">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381">
        <property type="entry name" value="RNA POLYMERASE II HOLOENZYME COMPONENT SRB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11221">
        <property type="entry name" value="Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK92791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="15598" checksum="8EF05B1656192E35" modified="2014-05-14" version="1">MGDRLTQLQDAVDQLATQFVACLHYVNKRHDLETLGPNDKVREVKDAPKEVDSLPPDEFRAGMVELSQDLIVKEQQIEVLISSLPGLDNSEMDQERYIKELEEDLKIAEAQRQEAIKEKDQILSELDSVIRSIRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGR3</accession>
    <name>X0CGR3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13854</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658422">
        <property type="protein sequence ID" value="EXK81782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGR3"/>
    <dbReference type="HOGENOM" id="CLU_744022_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="372" mass="38841" checksum="DF981CD766F65D9E" modified="2014-05-14" version="1">MGRLPGGLEPKPSPAPALSGNIARVTAASGTESNAVPDSNAGQGTKWFVKGGTFKFRIQTDFALSYASVAPALIPAEDGAGAEVPVLNGGPHPTKTNIFSRPMQVTTDIVSELSVVIMETVSAKIIGGWTGASFDIKSVPTGTWGKYSTDTDPSQSDASSLLSHDGATVPLPMGLLLSSPAPILALSTIPTFSASDAAKMGVVDLRFIPTMPGTNWFVPGYDPIRKAVPDTSVPGGLNYVAVSPDLNAKSGVIMAPTQVRYTPAELSSKEISETNQQLWDGMGTDWVKYASDKKALVNDTTDGLLVTVKKIFGWAQSFPATSTAAVTSAPSPWQLKGNFPAKLVRSANKDGTVVKGLEATYLALPRHAVVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGU5</accession>
    <name>X0CGU5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ML-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_07455</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGU5"/>
    <dbReference type="eggNOG" id="ENOG502R2RV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004278_0_0_1"/>
    <dbReference type="OrthoDB" id="5312224at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF6">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="434"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="479"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="510"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="622"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="9">
        <location>
            <begin position="108"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="710"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="909"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="961"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="712"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="782"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1017"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1129"/>
            <end position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK90049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1211" mass="131653" checksum="CF94B6291A12A2D4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGZ2</accession>
    <name>X0CGZ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Ubiquitin-like modifier-activating enzyme ATG7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autophagy-related protein 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_06782</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATG7 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGZ2"/>
    <dbReference type="eggNOG" id="KOG2337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="338614at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019778">
        <property type="term" value="F:Atg12 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019779">
        <property type="term" value="F:Atg8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01486">
        <property type="entry name" value="Apg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.70:FF:000001">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme atg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000243">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.100">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.70">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006285">
        <property type="entry name" value="Atg7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032197">
        <property type="entry name" value="Atg7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042522">
        <property type="entry name" value="Atg7_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042523">
        <property type="entry name" value="Atg7_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01381">
        <property type="entry name" value="E1_like_apg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF3">
        <property type="entry name" value="UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16420">
        <property type="entry name" value="ATG7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like modifier-activating enzyme Atg7 N-terminal" evidence="9">
        <location>
            <begin position="5"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="8">
        <location>
            <begin position="349"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606285-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK90528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="695" mass="77848" checksum="6B504345BB6902F8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CH49</accession>
    <name>X0CH49_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP-dependent RNA helicase mtr4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_04790</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CH49"/>
    <dbReference type="eggNOG" id="KOG0948">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002902_0_1_1"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18024">
        <property type="entry name" value="DEXHc_Mtr4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13154">
        <property type="entry name" value="KOW_Mtr4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000003">
        <property type="entry name" value="ATP dependent RNA helicase (Dob1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000083">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000141">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.300:FF:000001">
        <property type="entry name" value="Mtr4 exosome RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF7">
        <property type="entry name" value="EXOSOME RNA HELICASE MTR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="166"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="402"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="369"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK93521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1094" mass="124045" checksum="5939F72CBE1579A1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CI16</accession>
    <name>X0CI16_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Alpha-1,2-galactosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_13439</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CI16"/>
    <dbReference type="eggNOG" id="KOG4748">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039079_3_0_1"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000237">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF8">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 34 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK82197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="41976" checksum="D0077CF2D5F40A18" modified="2014-05-14" version="1">MLQLKRLPWSTAAVALKAVIVLFGILLCYQAYTFYGEWSWPKSFTYGTTQDPVSLVHPHGGSQCLPSLNSSLLLEAKTIRNACRHMPPYPSSDVRIGRVTAHFGSVQEHYQKALRTHVLHSMIHDNDLEVMCTPVVDSLWNKPAFILSLLLDEMVKPAQERLEWLFWVDRDTLILDQCRPLSSFLSPHDVDESDETEDTDDSEPERSNETKHDDIHLLVTNDWNGLNNGVFFVRVNQWAIELFSDIAAFRYYRPNVSLPFTEQSAMEIIMNEPKFKANVQVIPQEWFNTYPKGSPTDFVEKADEDGLEDYHARRGDFLLHFAGRGGRDKLINEWTEMLQGTRSIWPKEEVQRNATTSIRGFWSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJI5</accession>
    <name>X0CJI5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_06552</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJI5"/>
    <dbReference type="OrthoDB" id="5413793at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF108">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="36"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK91004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="416" mass="47012" checksum="BB2E2DCE43C2E21E" modified="2014-05-14" version="1">MVVLERAEFDPRHGNGQSVFDLNVALMVITNILMILRLYVRGIMAKNLGWDDLLAVVAWGLVMTFSCIEIVLLTKGVGYHIQDVPKETLLQFLSLSPVDKLVFILAGGFVRLSILACLPRINRDRSFMTCVYGVFVATIITAVASFLFVLLSCSPVSYVDSFLSLIHYSETELDRDVFNAAKPDRQCVSKYSLSRMRWAHSIMSTILNVVILSLCIWVSASTNKTRAQVIKMTLMLLLGLFAVVSTITRLILLLTTNMNVDMLVNHCRVLRITTDIYYRTYISLRVAPFFSLEINSGLWCGCLPAFQPLFEWTNNHYYNHYNMRKLSRSSAQEPLNDSWNRDYMTANPHVSIHGQPRDLKGNKTASDAESATGFAMLENERGIKLTTEFSVHVEDRVYTGEGSEDIVSRTPAWNAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKF8</accession>
    <name>X0CKF8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_06719</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKF8"/>
    <dbReference type="eggNOG" id="KOG0314">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019105_1_0_1"/>
    <dbReference type="OrthoDB" id="106784at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16620">
        <property type="entry name" value="vRING-HC-C4C4_RBBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014891">
        <property type="entry name" value="DWNN_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033489">
        <property type="entry name" value="RBBP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025829">
        <property type="entry name" value="Zn_knuckle_CX2CX3GHX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439:SF0">
        <property type="entry name" value="CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08783">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13696">
        <property type="entry name" value="zf-CCHC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01180">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51282">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DWNN" evidence="9">
        <location>
            <begin position="5"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="354"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="584"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="370"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="432"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="601"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK91304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="621" mass="68205" checksum="3D10D76E41208ABD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKG5</accession>
    <name>X0CKG5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKG5"/>
    <dbReference type="eggNOG" id="ENOG502RKHX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1489070_0_0_1"/>
    <dbReference type="OrthoDB" id="4367324at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="190" mass="21239" checksum="41976A01BCFE35BC" modified="2014-05-14" version="1">MDQSSILSLLSTRNTTLTNNTRVRSLHLPTMIPMDPENITRWNDFNLININNAYGDLLSKPSNIILGQGDDKHFGNQSKLRNYAFDPLISTLRPLVSESARVLGQRLGFAPTIDWHQDVPLAGPQVVGNALRPSLTIFAATTPRTSLVTSMVYVSSVWCSTDIETDGRESTWPVQHLAKYAQHSGNRYMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLJ9</accession>
    <name>X0CLJ9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLJ9"/>
    <dbReference type="HOGENOM" id="CLU_2263869_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="103" mass="11578" checksum="969D04337497FBE1" modified="2014-05-14" version="1">MRCCQPPAATLRVFEANCCCFYFCCAFLPSFLYCTAPHYTPVFCAALYLPCQHFQNLIASARKESANMEGRGRWGLPAEYLRFNQCLTLQSGRLNGIPISVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMY6</accession>
    <name>X0CMY6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Succinate dehydrogenase cytochrome B subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_04104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMY6"/>
    <dbReference type="eggNOG" id="KOG0449">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094691_0_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03499">
        <property type="entry name" value="SQR_TypeC_SdhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978:SF5">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK95541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="19840" checksum="A65CEC404A219E06" modified="2014-05-14" version="1">MLAQRVGVAALRQGATKPFFAQNIPKAALAAGISTSSPLRAVGSTKVSQQDGHQILVNQRLNRPVSPHLAIYKIEQTWFGSSAWNRITGCTLSATMYGFSLAYLAAPLVGLHLESASIASFAAGLPLAIKGGIKFTLGFPFVYHAISGFKHLLYDAGKGFAKTTIIQADKYIWAASFLGAIGLVAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNB7</accession>
    <name>X0CNB7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Acyl-CoA desaturase</fullName>
            <ecNumber evidence="16">1.14.19.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_05807</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:19721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:57394"/>
            <dbReference type="EC" id="1.14.19.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="16">Expected to bind 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.1" evidence="16"/>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNB7"/>
    <dbReference type="eggNOG" id="KOG0537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027359_3_2_1"/>
    <dbReference type="OrthoDB" id="10260134at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000004">
        <property type="entry name" value="Acyl-CoA desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009160">
        <property type="entry name" value="Acyl-CoA_deSatase_haem/ster-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001522">
        <property type="entry name" value="FADS-1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000345">
        <property type="entry name" value="OLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00476">
        <property type="entry name" value="FATTY_ACID_DESATUR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0249">Electron transport</keyword>
    <keyword evidence="15 16" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8 16" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 16" id="KW-0349">Heme</keyword>
    <keyword evidence="12 16" id="KW-0408">Iron</keyword>
    <keyword evidence="4 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="18">
        <location>
            <begin position="348"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK92778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="475" mass="53316" checksum="7343F70C07189833" modified="2014-05-14" version="1">MATATAAGKNAQPFPDGTKDYVPLRAGGAKKDTNKVHIADTPMTWSNWPQHINWLNTTLVIFVPLAGFISAYWVPLQLKTALWAVFYYVHTGLGITAGYHRLWSHSAYKGTTPLKIYLAAVGAGAVQGSIRWWSYGHRVHHRYTDTDKDPYSVRKGLMYSHMGWMILKQNPKRQGRTDITDLNEDAVVVWQHKNYIKCVLFMALAFPALVAGLGWGDWWGGLVYAGILRVCFVQQATFCVNSLAHWLGDQPFDDRNSPRDHVITALVTLGEGYHNFHHEFPSDYRNAIEWWQYDPTKWSIWCWKQLGLAYELKEFRANEIEKGRVQQLQKKLDQKRATLDWGIPLEQLPVVDWDDFVAQAKAGKGLVAIAGVIHDVTDFIKDHPGGKALINSAIGKDATAIFNGGVYLHSNAAHNLLSTMRVGVLRGGCEVEIWKRAQFENKDITYMNDSAGQRIIRAGSQVTKIVQPAASADAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQC4</accession>
    <name>X0CQC4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQC4"/>
    <dbReference type="eggNOG" id="ENOG502R0VU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027514_2_2_1"/>
    <dbReference type="OrthoDB" id="3251507at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027796">
        <property type="entry name" value="OTT_1508_deam-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14441">
        <property type="entry name" value="OTT_1508_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="518" mass="59435" checksum="E2FFB36C0696848F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQD7</accession>
    <name>X0CQD7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pathway-specific nitrogen regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502SAW3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_277723_0_0_1"/>
    <dbReference type="OrthoDB" id="5369448at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="707"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1120"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1230"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="441"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="825"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="854"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="913"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1120"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1240"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1253"/>
            <end position="1290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1324" mass="147719" checksum="CC0E39F6708565E2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR86</accession>
    <name>X0CR86_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR86"/>
    <dbReference type="eggNOG" id="ENOG502RJ6M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2527571_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939558" evidence="2">
        <location>
            <begin position="17"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK96955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="80" mass="6924" checksum="4F8056B3D5C5DEF8" modified="2014-05-14" version="1">MHASAAVLAFVAVAAAAQTPVAPVATPVATPGAPTNGTKPGSGSGSGSGSGSGSGSTPANGAAALGLSGLAGALAVALAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRZ3</accession>
    <name>X0CRZ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">X-Pro dipeptidyl-peptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10638</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRZ3"/>
    <dbReference type="eggNOG" id="ENOG502QUES">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035441_0_0_1"/>
    <dbReference type="OrthoDB" id="5959877at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361:SF2">
        <property type="entry name" value="DUF885 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="GLR0591 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="605" mass="69567" checksum="8370894133A3AB84" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSG9</accession>
    <name>X0CSG9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_04388</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSG9"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000012">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF201">
        <property type="entry name" value="MFS AFLATOXIN EFFLUX PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="541"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="86"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="573"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK94248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="596" mass="65226" checksum="9F406F0981E625A8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT07</accession>
    <name>X0CT07_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Formin GTPase-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT07"/>
    <dbReference type="eggNOG" id="ENOG502RXE8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008022_0_0_1"/>
    <dbReference type="OrthoDB" id="2155261at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051661">
        <property type="entry name" value="Actin_filament_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47102">
        <property type="entry name" value="PROTEIN BNI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47102:SF2">
        <property type="entry name" value="PROTEIN BNI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06371">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formin GTPase-binding" evidence="2">
        <location>
            <begin position="285"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="749"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK94453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="804" mass="90030" checksum="B16814BD796F0668" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT24</accession>
    <name>X0CT24_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT24"/>
    <dbReference type="HOGENOM" id="CLU_038504_1_0_1"/>
    <dbReference type="OrthoDB" id="5593235at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="448" mass="50882" checksum="CBB455DEE85C2DD1" modified="2014-05-14" version="1">MKPSDLPTSYSRAAARALNCTRGHIGLCAIILMLMMSTLVWRQRDLVAVKLPVMEQRPPTTLDSKAPTIAGINGTLDRFWSSNGESVQDLVHWSKPKGVDKIMGLVFYGRRQSVSILDCYLKRNLAKNGGLLDGVIFVERTKDPHDLALLKKLLESESSYEKWSVEMSGDDNFSSGFGNSYDRVEDHVMYVKIDDDIVFMEDTVIPSIVKKRLEHPEYYIVSANVVNQPLLSWVHWNLGAIRPYLPEVDSEGKAMPSKQSGQKPLDWNPSNLPPWNGPEGFSLDNWEPNDTTHRWLPLDKGGKDHILDTTPIEATEYHPMGRGWTQWTIGAQEHFSFFENLWKKKLSAYKFETWDFQYERMGIQFVALLGRDINRAKPIEADDENHFSCNMPRALGRHAVADGRGVAAHYSFGSQRAGMDRTDIIDRYRSFARNNICTGPMLWAPGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTY9</accession>
    <name>X0CTY9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK85962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTY9"/>
    <dbReference type="HOGENOM" id="CLU_3014192_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="56" mass="5869" checksum="82E94D5369FC2B62" modified="2014-05-14" version="1">MSHLAKSLRISSLGVVPSAVPSLESVPTGQELRSAPSTLDEEDLMDSDAALYALVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVX5</accession>
    <name>X0CVX5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">O-phosphoserine phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_01477</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.3" evidence="4"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVX5"/>
    <dbReference type="eggNOG" id="KOG1615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036368_5_1_1"/>
    <dbReference type="OrthoDB" id="27226at2759"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07500">
        <property type="entry name" value="HAD_PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000143">
        <property type="entry name" value="Phosphoserine phosphatase serb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050582">
        <property type="entry name" value="HAD-like_SerB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004469">
        <property type="entry name" value="PSP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00338">
        <property type="entry name" value="serB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344:SF2">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01137">
        <property type="entry name" value="C1.6.1:_Phosphoserine_Phosphat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01136">
        <property type="entry name" value="C1.6:_Phosphoserine_Phosphatas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00029">
        <property type="entry name" value="phosphoserine_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="114"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR604469-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK98625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="478" mass="53076" checksum="A388198DD28D89B9" modified="2014-05-14" version="1">MADQTSPTKQNVTRPQLGSMRSSSYLSDHQEYRPPRPDSSRQDQLFHGIDTVIEDTSNSPVPQTRPILPFNGIPSEENPPTVVDSGLSHSYSHPNCAPRAGEKTDRLIATLFYKPRGEDQGSRSPVKTTFADSNESLPANLAPTTDPNEYPLEPPTQESEQLDHIYGSYISPLCITSFLHLMSSFPLPQDADEPHSSHRCLDNQEQPRIVELTLSPTPSPEYLSLDDLRKHEMIYRFEQEWNVDVVLQRDTVWRRHPRLVVFDMDSTLITQEVIDLLADHVKDPPDLAARVAEITHRAMMGELEFEASFRERVALLKGLPANLFEGLRPVLDVTKGVPELIKAFKRLGVKTAVLSGGFQPLTGWLAGQLGIDYAHANHVVIQDGKFTGEVEGVIVGKERKRDLLVDIAAKEGIDLCQVIAVGDGANDLLMLDKAGLGVAWNAKPRVQMEANARLNGESLLDLLYLLGFTSEEIDALVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXK7</accession>
    <name>X0CXK7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0507 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502R3ZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030133">
        <property type="term" value="C:transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097422">
        <property type="term" value="C:tubular endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045022">
        <property type="term" value="P:early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000443">
        <property type="entry name" value="Putative vps9 domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051248">
        <property type="entry name" value="UPF0507/Ank_repeat_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G09870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="3">
        <location>
            <begin position="343"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1285"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="540"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1301"/>
            <end position="1314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1314" mass="146622" checksum="65CB1424F14064F4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D090</accession>
    <name>X0D090_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED5</name>
        <name evidence="11" type="ORF">FOQG_00219</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D090"/>
    <dbReference type="eggNOG" id="ENOG502R1HB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004096_0_0_1"/>
    <dbReference type="OrthoDB" id="5322661at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014801">
        <property type="entry name" value="Mediator_Med5_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35784">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35784:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08689">
        <property type="entry name" value="Med5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1002"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK99826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1043" mass="115617" checksum="A0077163DEBE4454" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0Z8</accession>
    <name>X0D0Z8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein SYG1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_02472</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYG1 (TC 2.A.94) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0Z8"/>
    <dbReference type="eggNOG" id="KOG1162">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006116_1_0_1"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14475">
        <property type="entry name" value="SPX_SYG1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF103">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 53 MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="505"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="551"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="583"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="705"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="730"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="775"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="9">
        <location>
            <begin position="1"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="8">
        <location>
            <begin position="664"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="81"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="165"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="860"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="923"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="940"/>
            <end position="959"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK97193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="982" mass="112947" checksum="D2DB4FB84E65EFF1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0D146</accession>
    <name>X0D146_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D146"/>
    <dbReference type="eggNOG" id="ENOG502SYW3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174967_0_0_1"/>
    <dbReference type="OrthoDB" id="3660930at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937571" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10274" checksum="76C74F694775ED26" modified="2014-05-14" version="1">MKPQVLLTAGLATVAVADQWPMAKEKCGRLGPMEWDPNDLPPDVDVMQIRMCADHPMGAGNYWGWGEYLPDWFPRNPFADMEINWLWWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2L3</accession>
    <name>X0D2L3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_02841</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H2B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2L3"/>
    <dbReference type="SMR" id="X0D2L3"/>
    <dbReference type="eggNOG" id="KOG1744">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075666_1_3_1"/>
    <dbReference type="OrthoDB" id="10254238at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000014">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="30"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK97788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="137" mass="14791" checksum="C2C8E23F002BD6EA" modified="2014-05-14" version="1">MAPKAADKKPASKAPATASKAPEKKDAGKKTAASGDKKKRSKTRKETYSSYIYKVLKQVHPDTGISNRAMSILNSFVNDIFERVASEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSSSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0D346</accession>
    <name>X0D346_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02997</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D346"/>
    <dbReference type="HOGENOM" id="CLU_069651_0_0_1"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="365" mass="41353" checksum="1CB8EF1EB9610227" modified="2014-05-14" version="1">MDAALHQLVAFRYKWITTENPETWRFEYLSLLLEADRVLEKRRSLQPDQESILRGEDRKLFQTLVDYQKLEKSLTVKLSVKTGWRPSNTEAAVIHADICQRCNRRRSVTVMTSYRICRYCSAGRNPTDAPEDHDDSTPVLWTECGPCQAQYVVDDDDKEKPPECFYCEGGSAAPTVQCSECLSRIIWPKEIDLKDVDPSNFQCCACVLGVSTIKNRETTVGDLVKHNISSFLRNDDNVIKTPLQGESLFHITRDCDLAHFSSKVEVMPDSNSPLELDGKFIRNQTELKMKLRDIILPQEIKNCAHCLEENSSLQSVCTDTTCVTVMCTDCANELYGESGGRNPQCVFCGSPVSKIRLPMSPVYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0D458</accession>
    <name>X0D458_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D458"/>
    <dbReference type="eggNOG" id="ENOG502RJTV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120086_0_0_1"/>
    <dbReference type="OrthoDB" id="3758478at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="17085" checksum="A7C25A4A44A30855" modified="2014-05-14" version="1">MASSQTKDIKSAIEATVKSYLASFIDARTQNNPSLVNRNVTSDCARSMLPSTLGGGFTMTNDAYLHVFADGLKVGGMHKNTISDLIIDVDARKAAVTTVAELVFNNGEELKLDFSWFLHFNEDGDKICKIVEFVDSDTFKGVKGREAELSGEAQKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0D477</accession>
    <name>X0D477_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_01004</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D477"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000164">
        <property type="term" value="C:protein phosphatase type 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000004">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="9">
        <location>
            <begin position="121"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXL01182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="325" mass="37349" checksum="3676B9050EBE3691" modified="2014-05-14" version="1">MADQHEVDLDSIIDRLLEVRGSRPGKQVQLLEAEIRYLCTKAREIFISQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFTMHGGLSPDLNSMEQIRRVMRPTDIPDCGLLCDLLWSDPDKDITGWSENDRGVSFTFGPDVVSRFLQKHDMDLICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAEKKQKYVPTTLGSTSTPINSPRKKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6I7</accession>
    <name>X0D6I7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_01538</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA1 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6I7"/>
    <dbReference type="eggNOG" id="ENOG502S786">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132216_1_0_1"/>
    <dbReference type="OrthoDB" id="1920692at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017384">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15879">
        <property type="entry name" value="MWFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK98739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="86" mass="9929" checksum="038AB9B2F0268402" modified="2014-05-14" version="1">MPVPFEALLPYAIMIGMFGISGTGLAVIKTWQNEGKRPRYSVDQWDRQMMDRDRRLTGTLRGQTDKPEAPLGFELNNPWKLETRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6Z3</accession>
    <name>X0D6Z3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16 17">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16 17">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_07211</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16 17">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16 17">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16 17">Belongs to the CDS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16 17"/>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6Z3"/>
    <dbReference type="eggNOG" id="KOG1440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10260889at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018269">
        <property type="entry name" value="PC_trans_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14 16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15 16" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR018269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK90422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="455" mass="51534" checksum="3BDC19628116E11E" modified="2014-05-14" version="1">MARPKRGVRFPNRNGSDGRRSSFSSEDGGSPTKLKSQSSGQLETVDEKQPAVSEKQAEYEKKKANFITRTFWTFVMFALFFAALFMGHIYIICIITAVQIVSFKEVIAIANVPSRARSLRSTKSLNWYWLATTMYFLYGETVIYYFKHIILVDKVLLPLATHHRFISFILYVFGFVFFVTSLQAGHYKFQFTNFAWTHMALYLIVVQAHFIMNNVFEGMIWFFLPAALVITNDIFAYICGILFGRTQLIKLSPKKTVEGFVGAWIMTIIFAMLLSSIMMRSKYFICPVNDLGANIFTGLKCDPNPVFLPKTYELPELFFLPDTANFSVTIAPMQIHALNLATFASLIAPFGGFFASGLKRTFKIKDFGDSIPGHGGITDRMDCQFIMGFFAYMYFHTFIAIHKVSLGSVLETAITSLNPDEQLELVKGMGHYLRNQGILAEDAVACIDRLLPVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7D0</accession>
    <name>X0D7D0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_01996</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7D0"/>
    <dbReference type="HOGENOM" id="CLU_013869_2_0_1"/>
    <dbReference type="OrthoDB" id="17255at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF18">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="49"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK99473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="652" mass="72514" checksum="17987844CEFEBAC8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8V0</accession>
    <name>X0D8V0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8V0"/>
    <dbReference type="HOGENOM" id="CLU_106360_0_0_1"/>
    <dbReference type="OrthoDB" id="5069382at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="227" mass="25797" checksum="69D161C48DC56E2B" modified="2014-05-14" version="1">MIKPAIDHMPPEILADICWYLCSHCTNDHLSHYPQPNSLATPKPGKLWGRPSAEDTTGLLSLARTCRVLNKAATPYIYHNIDARGWPEEKITEFLRDRRQLQERSFVRRLTMPGLQLLSLVDRGNSFGQTLASKAQKKLHDLRYLHLKNTHSKAVRDLSTLENLFEMAPNIKTLVIESHHLEWKTDPEGPPMMPLANLTCLKLLNKGSSRNATLLSHSYTYASQHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBF5</accession>
    <name>X0DBF5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBF5"/>
    <dbReference type="eggNOG" id="ENOG502SPGI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_384965_0_0_1"/>
    <dbReference type="OrthoDB" id="4966at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="699" mass="79582" checksum="E60F709FE63F7DBA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBI8</accession>
    <name>X0DBI8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7729 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00864</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBI8"/>
    <dbReference type="eggNOG" id="ENOG502S3AD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042319_0_0_1"/>
    <dbReference type="OrthoDB" id="2564812at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056146">
        <property type="entry name" value="DUF7729"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39460:SF1">
        <property type="entry name" value="C6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39460">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24855">
        <property type="entry name" value="DUF7729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937539" description="DUF7729 domain-containing protein" evidence="1">
        <location>
            <begin position="46"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7729" evidence="2">
        <location>
            <begin position="114"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXL00919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="356" mass="39009" checksum="B8C80CD43B5C3737" modified="2014-05-14" version="1">MASSSWSASTTTCSRPKSTSYRAPRLRIALSFLLLLACLTSTVLAGTETSSSSLRHRRHHAPTINRYELHRRKDEDEVKEIVNKETPSKTEGKSKATTVTIQRAAKTAAATNTPLPEAFDGNLSAELSTTSDSNCPAFLNGILSDPSYETCYPLSMMLQTSRGFFEAQKQLLSIVRVLDATCAANVTYCTDFFDAAARNLTASENCKQEWESGNTIVKQFLYGMKAYEMMYKATCLQTPEDDMYCYANAVTNTTTAANAYFYYLPYNLTLPGSTNPSCSWCIQETMNIFHAAAEDRSQPVALTYESAARQVNTLCGPDFVNSTLPPEETNLAHIFAPSWVGLVLALGSAALVNAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DFP0</accession>
    <name>X0DFP0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_05431</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DFP0"/>
    <dbReference type="eggNOG" id="ENOG502RXKD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048316_0_0_1"/>
    <dbReference type="OrthoDB" id="19981at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021013">
        <property type="entry name" value="ATPase_Vma12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11712">
        <property type="entry name" value="Vma12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738244" evidence="8">
        <location>
            <begin position="20"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK93297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="275" mass="30985" checksum="59A93C67D5495A55" modified="2014-05-14" version="1">MVLLTMTSSILEALSIVEATETPQIEDHDRTEEQESQQPTKEPTLDDPKLGNPISHGQIVDLWKQLKAQGNSNFTLEQLLRGASVYIPPPPPKPEPSPEYKALMARLRREEEARTYERMINPPPQHETFKDHFPSSAAAFAAANRPTSSADLGDDDMAMEEVHKQITLIINFLVSIAGVAGTLWVTARWWSLPARMFLTMGGSILVAIAEVVVYNAYIWKMDQGRKKHGKVKEVREVVESWVLGKDEDEKSVLIKEKDRTEDGVRKRKTEAKVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0DFV5</accession>
    <name>X0DFV5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_05495</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DFV5"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_43_4_1"/>
    <dbReference type="OrthoDB" id="6339427at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF4">
        <property type="entry name" value="SYMPORT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="505"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="118"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="646"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="654"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK93372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="666" mass="74336" checksum="122760C7A2459DC7" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0DIQ4</accession>
    <name>X0DIQ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Meiotically up-regulated gene 154 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_04398</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DIQ4"/>
    <dbReference type="eggNOG" id="ENOG502SE58">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044030_1_0_1"/>
    <dbReference type="OrthoDB" id="3363151at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043007">
        <property type="term" value="P:maintenance of rDNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007096">
        <property type="term" value="P:regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018819">
        <property type="entry name" value="Nur1/Mug154"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28293">
        <property type="entry name" value="NUCLEAR RIM PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28293:SF1">
        <property type="entry name" value="NUCLEAR RIM PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10332">
        <property type="entry name" value="DUF2418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="298"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK94267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="50916" checksum="675F8EC5DC2DF11D" modified="2014-05-14" version="1">MPRLVRRQPLRERIMAAINPMDFLLWLSEELETRDWDSASVGTQMGLAMNFVFLLARANSGSSTPSDDIFSDETSSGWLSFLVYPLVWALIAFSFTNAFYTITRTRKYRLFLAKVDKPLSTPSARRVKVSQSSASPSTPLSYLANLITPESAESRAHPDKTSDVWELSVWDPLPVSLRLACLFGPGHVLVYMIFLPLAPLDPRPSVTVLNTIVLQALISAQLLFFCSRFAQQAKDKAVIQEQVMKEYDTKFVHPRLHPTVRDIGTQFSTDQPDDYQEFVQTGTPTVQIRHGFQVHSNPYTGTDHTPEERSLTPTSNNVMKPHMFTPPTATRRSEAFRPATSQRGTVPRHSLPAGYTSTGTSSGVQGMNFGGNMGIHTHNKSPLKKATSLNELNPQEAASPRNSREMAAYEQRNWGATTPSKKLESRRLTGSRPNGGGNPFAGLGRQQAPSDNRHPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>X0DL30</accession>
    <name>X0DL30_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Guanine nucleotide-binding protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_03786</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DL30"/>
    <dbReference type="SMR" id="X0DL30"/>
    <dbReference type="eggNOG" id="KOG0082">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014184_6_0_1"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000001">
        <property type="entry name" value="Guanine nucleotide-binding protein G(I) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000051">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="175"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="200"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="269"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK95087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="353" mass="41024" checksum="D763C1919E8B50E7" modified="2014-05-14" version="1">MGCGMSTEEKEGKARNEEIENQLKRDKMMQRNEIKMLLLGAGESGKSTILKQMKLIHEGGYSRDERESFKEIIFSNTVQSMRVILEAMESLELPLEDQRMEYHVQTIFMQPAQIEGDVLPPEVGSAIEALWKDRGVQECFKRSREYQLNDSARYYFDNIARIAAPDYMPNDQDVLRSRVKTTGITETTFIIGDLTYRMFDVGGQRSERKKWIHCFENVTTILFLVAISEYDQLLFEDETVNRMQEALTLFDSICNSRWFIKTSIILFLNKIDRFKEKLPVSPMKNYFPDYEGGDDYAAACDYILNRFVSLNQHETKQIYTHFTCATDTTQIRFVMAAVNDIIIQENLRLCGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0E161</accession>
    <name>X0E161_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_00393</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the RBR family. RNF14 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="3"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E161"/>
    <dbReference type="eggNOG" id="KOG1814">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021364_3_0_1"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20354">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23134">
        <property type="entry name" value="RING-HC_ITT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23820">
        <property type="entry name" value="RWD_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000416">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054694">
        <property type="entry name" value="Parkin-like_IBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047548">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22605">
        <property type="entry name" value="IBR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RWD" evidence="14">
        <location>
            <begin position="10"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="186"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="190"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="309"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="508"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="556"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="664"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="508"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="565"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="583"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="619"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXL00083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="684" mass="74734" checksum="371147F86057F487" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0E2D7</accession>
    <name>X0E2D7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor tau 55 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E2D7"/>
    <dbReference type="eggNOG" id="ENOG502RYP8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042838_1_1_1"/>
    <dbReference type="OrthoDB" id="414418at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF51">
        <property type="entry name" value="TRANSCRIPTION FACTOR TAU 55 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="31865" checksum="28861EF04F6A4B47" modified="2014-05-14" version="1">MPLEVIYVTRHGFRSGWSVDPLTGVYTGFIRSPTGIPADPALTSHGVSQSKEMGKHLMTLDPPIDAVYSSPYYRCLQTITPFIELKQQQLKDQPGIRGSAAATIRPEHGIGEFFGAAPFDHPTPASSKRLKELFPAFDENYASAITPSRKGETINDLYGRVAAAVRAIIERCDAEGHRAVVLCTHAAVVITLGRILTGRIPKAVEEEDFHAFTCGLSTYRRRGPGLKRTLMLGPNKSHPPTSDLSPVGEWQCEIDSDCGFLTSGEERGWKFSGDESFPGTGSMSQVDIESKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2C3</accession>
    <name>X0B2C3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_19006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="KI979560">
        <property type="protein sequence ID" value="EXK76245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2C3"/>
    <dbReference type="HOGENOM" id="CLU_017286_3_0_1"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152079" description="Metalloendopeptidase" evidence="2">
        <location>
            <begin position="23"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="3">
        <location>
            <begin position="36"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK76245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="402" mass="45208" checksum="24FEC410CEE1EEFB" modified="2014-05-14" version="1">MGSMSFKTVAILAFTVSQPALGAVFPSNIFNRSEIEAMPLEKRGSMDAYQLWDSAEIPYILQSLPHDLSESIRSAMREWEQSTCIRFLPKTTQSAWANFKKYDDGCFARGLGSPGSGERIINLDYPNAWEKIISVGTYKACLEAGTPSHELGHLIGLTHEHQRPDRDQYIRILTDRIEKDSLDQFTIDTTADVHVPFDYNSVMLYDTKAFAKTNALTPISGSKSLKHTMETITDKKISPWNSPTANDFKAVNDGYSCEEYYTRVIPQCLSGSIPSNSDFSSYSFILDKHTEAYMRANGYTHVAAHQNCRSNRAGQDTDNWGFTPLNGWGPRAQYKVTTNRCKKDFDRHASRYEVALCKSDNEGACDIKCGLRRVCPFDTSGKQVDSKAIDVVDNNLWICHPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3X7</accession>
    <name>X0B3X7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">(S)-ureidoglycine aminohydrolase cupin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979503">
        <property type="protein sequence ID" value="EXK76461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3X7"/>
    <dbReference type="eggNOG" id="ENOG502SBFV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1001327_0_0_1"/>
    <dbReference type="OrthoDB" id="5182387at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008579">
        <property type="entry name" value="UGlyAH_Cupin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40943:SF1">
        <property type="entry name" value="CYTOPLASMIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40943">
        <property type="entry name" value="CYTOPLASMIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05899">
        <property type="entry name" value="Cupin_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="(S)-ureidoglycine aminohydrolase cupin" evidence="2">
        <location>
            <begin position="81"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="(S)-ureidoglycine aminohydrolase cupin" evidence="2">
        <location>
            <begin position="220"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="278" mass="29761" checksum="608622C3C504F644" modified="2014-05-14" version="1">MAQPTTHIIHGGKQASPNSTWTNFEWEEPKLGKQVHGEVTTARAFGTSGNLSSGFWRTSATSPGANSDGSHNLTYSSPLGDETACVIDGSATLTVVSTGAKYKVGPGSIISSPKGLEVYWEIDAPFFKKYWCIWNGTKAVANPPTDLLIGNVSDSPDWVDYNFTEPKEGDLVAGELYFIRNGGSTGSMLSGVWRSGKGIAGSDVDDEGTMTTPYTGTLGDETILLLEGEVDITETESGKKHNFRAGDAIGLTSGMHITWVSKGPFTKKLWVITRDVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4G7</accession>
    <name>X0B4G7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658650">
        <property type="protein sequence ID" value="EXK77035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4G7"/>
    <dbReference type="HOGENOM" id="CLU_011527_0_1_1"/>
    <dbReference type="OrthoDB" id="414774at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45588">
        <property type="entry name" value="TPR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45588:SF1">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="556" mass="62240" checksum="DB788CF6420F5369" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4Q7</accession>
    <name>X0B4Q7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979455">
        <property type="protein sequence ID" value="EXK76716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4Q7"/>
    <dbReference type="eggNOG" id="ENOG502QTTH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038069_0_0_1"/>
    <dbReference type="OrthoDB" id="5819478at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36851:SF1">
        <property type="entry name" value="GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36851">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="61572" checksum="B8352BC2792A52F6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0B551</accession>
    <name>X0B551_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658670">
        <property type="protein sequence ID" value="EXK76881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B551"/>
    <dbReference type="HOGENOM" id="CLU_2885893_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="63" mass="7037" checksum="DDF3D58F2274C429" modified="2014-05-14" version="1">MANPTSSCASKSTKEAVLLMASGTMKPLTTTLWNPRPPEKYRLRLPCSRVAHRIFPRPNRGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAA1</accession>
    <name>X0BAA1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Myo-inositol 2-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_16260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979351">
        <property type="protein sequence ID" value="EXK79095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAA1"/>
    <dbReference type="eggNOG" id="KOG2741">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_0_0_1"/>
    <dbReference type="OrthoDB" id="446809at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000017">
        <property type="entry name" value="Oxidoreductase family NAD-binding Rossmann fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF3">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="4">
        <location>
            <begin position="137"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK79095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="355" mass="38694" checksum="EB7D9161251700D1" modified="2014-05-14" version="1">MAPRKLQVGVAGLGRMGKRHALNFHQNVPRAVLVAVTSPDAAEREWAAENLAPDGVAIYENYSDMIAHVGLDAVCVASATAVHAEQTNAAIAAGKHVLCEKPLGTTVEISQSVVDAAATRPDLKVMCGFSRRFDASYRDAYEKTKSGLIGRPSVLRSQTCDVLDPSGFFVAYAQFSGGIFVDCSIHDIDLALWFFGQQSKVRSVHAVGITAVEPDLRQYDDRDNAVGIVEFYDGRIAYLYASRMMAAGQEDTTEIIGTKGKLSVNLIPVENHVRIYGQEGIRHELPQNYWGRFQAAFTREAIEFTDCVLDDKPVPVELASAVTAVRIGAALQRSMIMGNKILFDESGNEVNRAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCS3</accession>
    <name>X0BCS3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_18979</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979553">
        <property type="protein sequence ID" value="EXK76274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCS3"/>
    <dbReference type="eggNOG" id="ENOG502T6DJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_476519_0_0_1"/>
    <dbReference type="OrthoDB" id="5057644at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019783">
        <property type="term" value="F:ubiquitin-like protein peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="6">
        <location>
            <begin position="249"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="139"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="431"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK76274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="572" mass="65079" checksum="7DF44255522DF101" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEZ1</accession>
    <name>X0BEZ1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658611">
        <property type="protein sequence ID" value="EXK77413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEZ1"/>
    <dbReference type="HOGENOM" id="CLU_013935_0_0_1"/>
    <dbReference type="OrthoDB" id="3549294at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="609" mass="67828" checksum="E573251B0F1F1E2C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFE8</accession>
    <name>X0BFE8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658592">
        <property type="protein sequence ID" value="EXK77568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFE8"/>
    <dbReference type="HOGENOM" id="CLU_2606150_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="79" mass="8932" checksum="A807C99F3D48AFBB" modified="2014-05-14" version="1">MAVPARLFNQCQLGKKTPSSRHWGLASKQSCLPGMETWDTSTSMALRPGRMWQDHSKYDDSGSSSANRYLHHPCLLLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFU9</accession>
    <name>X0BFU9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979394">
        <property type="protein sequence ID" value="EXK77359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFU9"/>
    <dbReference type="HOGENOM" id="CLU_069414_2_0_1"/>
    <dbReference type="OrthoDB" id="2942798at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052396">
        <property type="entry name" value="Meiotic_Drive_Suppr_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="28284" checksum="94F542114250BDBA" modified="2014-05-14" version="1">MENSDGIPSSPTSDILTEGVMQPEDTRFRFGTRTITARGGPADHCHHNVLCLRLQQTFLDRVVQSLFGVLSGAIGPWLQSKFPEWFLPERIVLKSQKPNWEEEFDKELEAYHKLQPLQGTVIPRFYGMIQFNDIRALILSDIGGNCLATPEGAVLDKQDLRPLLEQAFTSLADLGAYHDDIKLDNFHLVTDNGKDKIMVLDLESVGFELSGEDLSRVAKGTPNWLINQYDNHLECMEYDGMILPKRPLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0BG87</accession>
    <name>X0BG87_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_17444</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979374">
        <property type="protein sequence ID" value="EXK77858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BG87"/>
    <dbReference type="eggNOG" id="ENOG502SH7I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2018619at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF23">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="82"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK77858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="689" mass="77080" checksum="332CB20C3FA6A9F7" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGI1</accession>
    <name>X0BGI1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_17697</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979382">
        <property type="protein sequence ID" value="EXK77589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGI1"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_4_1"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF164">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="500"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK77589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="59341" checksum="D3F96DDE91053D00" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI31</accession>
    <name>X0BI31_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_13787</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="JH658421">
        <property type="protein sequence ID" value="EXK81805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI31"/>
    <dbReference type="HOGENOM" id="CLU_000631_11_0_1"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935732" description="alpha-glucosidase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="7">
        <location>
            <begin position="311"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="8">
        <location>
            <begin position="753"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK81805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="978" mass="110710" checksum="6B5F18C616DE9D02" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJP4</accession>
    <name>X0BJP4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJP4"/>
    <dbReference type="eggNOG" id="ENOG502ST09">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054614_3_0_1"/>
    <dbReference type="OrthoDB" id="5343383at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="270" mass="31588" checksum="FE0E496006344809" modified="2014-05-14" version="1">MAPLSENSYSPAEITAILLDFYLFLTTLHYDAQYLKLPPAEGWPGMESLLKSLGSSEMVGQVMKRIPYFDNDCKAFIHYKSRPVDYPTLPKDCFERVMWGRVSGSDEIYSERRQITIDMRDVFPLATGREAWGKYIWLNVRDGEITVEERLMHDLPQVDLKVFFDGLKQDYITLKLIPCRGRITIEADKIKERPGGEIITEEEVIAQEEAWGTALDIQYIRQLYRGFGWPLAFRRDEAFDAVDQLMDKLAEHRDEWEPTEEDWDDDDHWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK27</accession>
    <name>X0BK27_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16543</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658501">
        <property type="protein sequence ID" value="EXK78814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK27"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_4_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF80">
        <property type="entry name" value="GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935780" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="33"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="364"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="667" mass="71489" checksum="02444F1B846AD2E7" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM71</accession>
    <name>X0BM71_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979345">
        <property type="protein sequence ID" value="EXK79579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM71"/>
    <dbReference type="HOGENOM" id="CLU_1635496_0_0_1"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050478">
        <property type="entry name" value="Ethylene_sulfur-biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795:SF39">
        <property type="entry name" value="AMINOTRANSFERASE CLASS I_CLASSII DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795">
        <property type="entry name" value="BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="2">
        <location>
            <begin position="3"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="162" mass="18313" checksum="D3F54F58FCAFE03C" modified="2014-05-14" version="1">MGGLRMGFLVTRNPVIKAAASQAAWFTWLTVASDKFVTRFLQQLDVIQDYLDNYCSRLTEAYRRTTMALNKYKIPFQRADAGLFVFIDLSRWVHNFDAGKMGSPEMQLCRMLIDNGVFLNPGQFAGCDRPGRFRLVYSQDSTVVELAIQRIGQALDTLSAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNP1</accession>
    <name>X0BNP1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979337">
        <property type="protein sequence ID" value="EXK80528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNP1"/>
    <dbReference type="HOGENOM" id="CLU_033726_0_0_1"/>
    <dbReference type="OrthoDB" id="125347at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF1">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="38082" checksum="A500265A8D466F30" modified="2014-05-14" version="1">MEFKDNYSAIAEANKQRRKLQNRKNQRARRQRIKGKDFGIDQVSSSFEIRRWRVDEVDEVDDGCSQDTNTDSTAVSINYHPSCTLPSTTKSVTAVQAPSSTDQLDQVMTIHSTPQPININFPLPSDQLLHLIQFNVYRAFISIKRTINTISLDPTTCPVFGPCLDDTTRYPPNPNIPSSLAPTVLQQTQYHFPWINIMPFARLRDNLIRREGRFDNFELWRDLVGDLMSYTAAPWQRGTPFSFSASTPETEQSRGFMLENYIDTDEITAGRNGLIIWGEPHDMQSWEATPGFLTKWSWAVEGCEELVEVSNRWRIRRGAEPMRLPTSVFGANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNZ3</accession>
    <name>X0BNZ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNZ3"/>
    <dbReference type="eggNOG" id="ENOG502QSKG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_1_2_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="38517" checksum="290E4B20CD72FFA0" modified="2014-05-14" version="1">MAEPTMNAEPDLVPDEQSDEEHDSSMGLSLASTSESLRSSILDYRKENGRTYHRYKDGKYNLPNDDVEKERLDLQHNLFILMLDNKLGLAPPNDPNSKAKRVLDVGTGTGIWAIDYADEHPEAKVIGVDLSPIQPDFVPPNVEFFIDDIEEPWNFSEPFDYVHSRMMTFSIKSWPNLVSSIYDNLVPGGYVELLEIDLFAHSDDNTLTEDHHLSKLIHLLDEASTKIGRPFQDNKKNKDILRDAGFVDIVETVFKWPTNRWPLDKRYKEIGEWNNLNMDSFKGLEALSMAALTRVLGWSQEEVTVFLAKVRRDLNDRTIHAYWPVYSTYGRRPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP91</accession>
    <name>X0BP91_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP91"/>
    <dbReference type="HOGENOM" id="CLU_3392363_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3396" checksum="D6F6CD860F224381" modified="2014-05-14" version="1">MQLGSLTPFSSQLKSTGQAEATVDPDSSTVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPQ3</accession>
    <name>X0BPQ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPQ3"/>
    <dbReference type="eggNOG" id="ENOG502RXU0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033727_0_0_1"/>
    <dbReference type="OrthoDB" id="18110at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23524:SF1">
        <property type="entry name" value="MRH DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23524">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="542"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="572" mass="60833" checksum="B5833EFB57C45B34" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ42</accession>
    <name>X0BQ42_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Ornithine aminotransferase</fullName>
            <ecNumber evidence="4 9">2.6.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_11534</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:13877"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="EC" id="2.6.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="4 9"/>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ42"/>
    <dbReference type="eggNOG" id="KOG1402">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_3_1"/>
    <dbReference type="OrthoDB" id="10261433at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:L-arginine catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010121">
        <property type="term" value="P:L-arginine catabolic process to proline via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000011">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK84275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="446" mass="48618" checksum="F8357003C07B59FA" modified="2014-05-14" version="1">MAPSATSPQLSTSKLSSTPLLSEKTARHVETWSKHIRGGFPTLPVAVESAKDHTITDVDGKEYIDFIGQFAVMNFGYSHPKIAKAAADQVYKMPLSGTAHISPLYVEFAERLTKKFGFDSIATMLSGSEAVESAVKIARKWAYLKKGIPQDQAHILTVDQCYHGLTLSTMPMATVSQKHFGQHLPNIGPYAPTSGKLVPFGDIDVLRDVFEQDGERIAAFFVEPVQGWAGTVVPPKGYLKAAQDLCRKHNVLLVCDEIQAGYGRTGKDLSFHHEPELEPDMVTMAKGITGGYYPMSVIMGKKHVMDLLNKNEVLSTYGASPIALSAALATLDVLEDEKISERSERLGNLLEKTIKELNPPHVKELRGIALFQSLVLDQSIPGVTPRRVQALAAHHGVLVGIGADRLRFSPPLTITDGDLVKALHVIAQCLEEVTRLGDFAGSEFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQR8</accession>
    <name>X0BQR8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS transporter, PHS family, inorganic phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14295</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979335">
        <property type="protein sequence ID" value="EXK81243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQR8"/>
    <dbReference type="eggNOG" id="KOG0252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_46_14_1"/>
    <dbReference type="OrthoDB" id="433512at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17364">
        <property type="entry name" value="MFS_PhT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004738">
        <property type="entry name" value="Phos_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00887">
        <property type="entry name" value="2A0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="516"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="59"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="545"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="550"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="571" mass="61960" checksum="3DD365EC19F02811" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRA8</accession>
    <name>X0BRA8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK81019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRA8"/>
    <dbReference type="HOGENOM" id="CLU_065839_0_0_1"/>
    <dbReference type="OrthoDB" id="3596450at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="4"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="316" mass="36648" checksum="D6975AE16D076D7D" modified="2014-05-14" version="1">MTAFKRFTELPRELRDRIWSLAIRDDHPGVHIFGQYVTGSHRILSWGGTSFDLAAPSWSRYFESLDEHRSDENISTYLIDGGLWTACHESRCIMEKHFKQSKRQSTLRPPNEYQIISSEKEIFKRATSGYFDGAPLEIVTVFPHRDLFILQHDDLDKIDWGSIGYEAALASTREEFHGVEHIAIEYDRAWGNGSSRGDVNYALLHAAVGANYTIWFIDRSLKRKSQASVFKEESDCSWKINAFYASDRKFLEINDTHALLEDWEYIGPVENYWYDHICDSLDFVRQLEIDLTDQYIAGGYEAEKPCTIRLLGWAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRD3</accession>
    <name>X0BRD3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979336">
        <property type="protein sequence ID" value="EXK81044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRD3"/>
    <dbReference type="HOGENOM" id="CLU_1250723_0_0_1"/>
    <dbReference type="OrthoDB" id="406634at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="221" mass="24472" checksum="13027E844E525D57" modified="2014-05-14" version="1">MLLALADRGSNPSNVDKRRRKYQDRRRRAMLPEDDTFGTTSSEHSSISSSLKPLGTLPNSWCGISNEVIEIFGRLLALYRSACDYNQDQTTIGLKIASKALCDIAVARELEIELLSVDFKTIVLLEEPQDFYVDTRDDNTPVSHLLETAEAYRKAGLLQLYLTFDDLVVNASGGQNASASSSDDAKDKASRAKSLIDLTLELVTTLERIPAESGSRFIHPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRQ9</accession>
    <name>X0BRQ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRQ9"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="32712" checksum="3EE8C14540F2CDE1" modified="2014-05-14" version="1">MGPGDPFNPDRDIPSLEGKVILITGGNAGIGKQSALALSKHQPSEIWIAARNAKKAETAIAEIKQQSPGVDVRFLELDLSSFASVKSAAQTFLKSVSRLDILMLNAGIMACPPGQTSEGYEVQFGTNHMGHALLTKSLLPLLTYTASSSPRSDVRVVSVSSVAHKFGPSGGIQFDTLKSTASGMSTTDRYGQSKLANILFIRELALRHTELTPVSIHPGTVKTDLQNSNGGSWMLSAFQKFVVPLVGVSVEEGAKSQLWAATAKEVKAGEYYVPVGVSGNGSQLSKDKVLAKKLWDWTEKELESQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSX3</accession>
    <name>X0BSX3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">Endoplasmic oxidoreductin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">FOQG_10945</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">May function both as a monomer and a homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSX3"/>
    <dbReference type="eggNOG" id="KOG2608">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="269384at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613:SF0">
        <property type="entry name" value="ERO1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613">
        <property type="entry name" value="ERO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017205">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 17" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 20" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935967" description="Endoplasmic oxidoreductin-1" evidence="20">
        <location>
            <begin position="23"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="16">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="90"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="413"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EXK84991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="23">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="600" mass="68393" checksum="78B78E0B69E3CDB8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUI3</accession>
    <name>X0BUI3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_13030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUI3"/>
    <dbReference type="eggNOG" id="KOG1812">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1012083_0_0_1"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045072">
        <property type="entry name" value="MKRN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224:SF10">
        <property type="entry name" value="IP09428P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224">
        <property type="entry name" value="MAKORIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="275" mass="31722" checksum="49FC2FDF1AB3E0A2" modified="2014-05-14" version="1">MGNTLERPTAPGDEFPWLFQQLRIQNHENRRLANALREEDRRRRRPEHRDRQPCRFYAQGFCFHGTDCRYAHDGPVTRTRQPDRRQREPCRFYAQGICTHGEACRFSHEGPRPLQETCRFFAKGFCKRGVSCRYAHDQPNTEWSEEPKHDSHIEKWTRQLGGAWVEFGDGVAVVKITLLSDFSAIQMRHLPSRSSARSVQELLADIGISVSISDINFIKLVKNRNGMAIVKVKDPEFAKSACWKLRTCVRAPDLEVTQIPVPLPEGSSFVVYIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUP1</accession>
    <name>X0BUP1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_13435</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUP1"/>
    <dbReference type="eggNOG" id="ENOG502SI7M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051062_2_0_1"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF7">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK82194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="230" mass="24583" checksum="8AB2A674EABE500B" modified="2014-05-14" version="1">MATKSIEEIRSHSPSPSALGLGQQIGNPSPLAMGTFATTLLTLSLSMMGFRGVETQTIFIGNLCFAAGLCMFVSAQWEMARGNTFGYSALSAYAVFYGGYGVILCPSLGVLESYGGPTPEYHNALGFYVLIWAVLTLFFMLGSAPINLVSFGIFTTIFFCFTLDAASNFAHADGKVEVAKNLMKAAGVFGFVSGLLGYYSCAAVMCADALPFELPCGDTSRFFKKTRKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVW3</accession>
    <name>X0BVW3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine zipper 2TM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVW3"/>
    <dbReference type="eggNOG" id="ENOG502T226">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081633_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="33952" checksum="3F32F0DC7CC6898D" modified="2014-05-14" version="1">MSKDYYEYEEYSRRRRDFSPDNYSGGAPGSQQQGPPPPPPPGAPPYASTSRLDDPYYGGMPPPPRERMTLEPPESQNRPRSVPPNTTMVRRSRSRSRPPSDDEDYDDRRSSRNRSQSPITRARNVVDENFSHSAGGIGAGILGAVVGGLVAREATEAATRRKHKTRGYEDENEDRTRLVSTILGAVAGGLGANALANRVEDSRERDRRRQLDWERERSYVREQEMPRYEQRRSSDRDREDDRRDRDRDRYDRGRALPQNDDDDYDFVYDDPRYEDREPRRRRSEDNYRYRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWE5</accession>
    <name>X0BWE5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Involucrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWE5"/>
    <dbReference type="eggNOG" id="ENOG502S9Q7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019744_2_0_1"/>
    <dbReference type="OrthoDB" id="5328813at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="471" mass="53302" checksum="64536D24FBFCA993" modified="2014-05-14" version="1">MNTSEKRRPGPGTSPAHTLRTGASSNNRNSMPAMPPRAAMASNANANPEETLDTTGGAPLKEKENAVTGSGSTKEKDRDKERKERREKREKKERERELEAALKEKDERIAYLEKEMGIMEREFHRELDKLSQNESETATFWQAKHSALNQQYLRTDTELRLLRAEVEVREGEREELREGWEVLRRELKERDDEIRGLRGQVRGLKEWVSNSTRTDGQECDEVFGDGMARLGNGLQNWVIVNFRKAKINLENLDEATLAEVNDLVPMYEELASTHKVYLLQSIVSKILVEMVFDAYFVGLSEEQTQQFRQLEKLVSSYADSDEAINQWRSSTLSLLRRDGSSLKESTSSVTEAILSRITRILDALCGTSPSEARDSGLRVLVNNSIELARLVAVQKAVLRVNMPTVLPHQRVMFESETMEDLGGEDEESLTGREICCVAFPGVIKHGDEHGGHLQYRNVILKARVLCSPEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX32</accession>
    <name>X0BX32_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX32"/>
    <dbReference type="HOGENOM" id="CLU_1185066_0_0_1"/>
    <dbReference type="OrthoDB" id="4582561at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="229" mass="25951" checksum="F56B16E1AD475F26" modified="2014-05-14" version="1">MHRAGERRFYTLFFVVLSWILMTVITEFQDFNADAFEEHLKQVSTLDAYGGNPGPMSFCQGIKEKNSYDFFNLTLACRFTVHIIVSCLIIDWILHFTKTRMTGDKVKYTQIGGESRTIFSFAETKGARLSLGVFWAAIELLTIIMIFIGLREMVELLDMHSADGGLSTWGFGQLVAVAIWFPVMIKFICLSIFGPRKEIKQKDNTDKPQVLEMVSYPQNKADNTASSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ03</accession>
    <name>X0BZ03_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ03"/>
    <dbReference type="HOGENOM" id="CLU_2223396_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="106" mass="11611" checksum="07DC77631B822E73" modified="2014-05-14" version="1">MNCVRSASECGRPDPAGLCLDPCVNAISCGQLFRPPVIFLPTLEVPRHVIYRSRSRPRSHLLAGEALTLVSWIPKGPYLPVWSNNSSGGQDGSRALVTDHCIEDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ91</accession>
    <name>X0BZ91_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11992</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ91"/>
    <dbReference type="HOGENOM" id="CLU_007201_2_0_1"/>
    <dbReference type="OrthoDB" id="2262349at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009074">
        <property type="term" value="P:aromatic amino acid family catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052780">
        <property type="entry name" value="AAA_Catabolism_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31644">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR ARO80-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31644:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="135"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK83834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="843" mass="94662" checksum="3A65F5658A1A0446" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ97</accession>
    <name>X0BZ97_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11997</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ97"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3160012_0_0_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="48" mass="5614" checksum="C3D6C096E36E9346" modified="2014-05-14" version="1">MTGIENKEFKWYQVREAFTNYKTYLLFIFFLSMNVPKGGLGTFAAQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0H2</accession>
    <name>X0C0H2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7732 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08786</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0H2"/>
    <dbReference type="eggNOG" id="ENOG502S4KZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060392_1_0_1"/>
    <dbReference type="OrthoDB" id="5425547at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056634">
        <property type="entry name" value="DUF7732"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42091">
        <property type="entry name" value="CONSERVED GLYCINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_7G02440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42091:SF1">
        <property type="entry name" value="CONSERVED GLYCINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_7G02440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24866">
        <property type="entry name" value="DUF7732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938988" description="DUF7732 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7732" evidence="3">
        <location>
            <begin position="123"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="286" mass="29621" checksum="F5CEB0048B4D2E4D" modified="2014-05-14" version="1">MRPDFAVVLFTLITSTVASAVDVPRHIKRIESEPSADEHELYKRRGGGGGGARGGSSGGGSRGSSGSGSRGGSSRGSSGSGSSRGSSSSGSGSRGSSYRPGSSGGSGGSRGVGPQPSFAGGRYYPGGSSRPYKSGGSSPGRIAPYALGGAALAFWPGVWLYGAYMYPYSHPYHYHNDTSDEDEERDVLCGCSRYEYCACDDNNSTQYFDELIGNGSYDALNKSIVNVAEVNGTMTILINGTLPNDTALPDENASDNGALSKRAFLTTENFGWVVILSIVLGIVEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0W0</accession>
    <name>X0C0W0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0W0"/>
    <dbReference type="eggNOG" id="ENOG502S46I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_8_1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="1">
        <location>
            <begin position="7"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="210" mass="23133" checksum="FCA1E9FF7BEF838C" modified="2014-05-14" version="1">MSPPTKYAVALFPGFQALDVFGPLDVLNFTSKRQPLELSLLHTSLDPVSTLEDDSPGRIGQSVVPTHTYDNAPEDIEVLLVPGGRGSRNPENVKRVREFVKERYPKLRFLLTVCTGSAIVAQSGLLDGKEATSNKRSFDWVETQGPNVKWVRNARWVVDGNIWTSSGISAGIDMIYAFIAEQYGQEIADDTADGSEYVRNTDPKSDPFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0Z4</accession>
    <name>X0C0Z4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0Z4"/>
    <dbReference type="HOGENOM" id="CLU_2922689_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="61" mass="6848" checksum="599C2D901FF469EE" modified="2014-05-14" version="1">MALCGTGSTSEIDFVPAYWRLGVTLGPQRDNDDRNKNGFVITESYEMLIKKRSVPISVEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1I7</accession>
    <name>X0C1I7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1I7"/>
    <dbReference type="eggNOG" id="ENOG502RZ72">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035633_2_0_1"/>
    <dbReference type="OrthoDB" id="5360701at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="412" mass="44766" checksum="7535B3C6E3449AB9" modified="2014-05-14" version="1">MSRVGTRHIGNICHRCAFTPAPTVANQAFVSGTLLAAIRHGRKTTIKGPRARWAATASTYPDLNIQPADADKVPRQLTDPTQLANIVESTKEKFLATDGIPAKQLTTAALETCLKAAQALQPQIHRAEAQSRTSTSKLMELGAERTGQRPNSMDPQLADSVKKISYSAYAIISQPNVEITPALLELYVAIQASLGRPESLPAVFEMFATKKKPVVKNGVVQYVASNPNAAVKAIEKGVADMALQTAIDAKNLDSALGVVEASFSLPAFKRQKLIKHSTTPALALGSLPFGIFGLASAYAAYWQNTMDISTATGLGVAGISGYFLVVGSMGMIAKLSNKDQMKRVTWAPGTPLRLRWLREEERAAMDKIACAWGFKEPWRHGEESGPEWEGLKEYMGYRQMILDRVEFMEGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0C230</accession>
    <name>X0C230_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="14">Cytochrome P450</fullName>
                <ecNumber evidence="14">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="14">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="14">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_10861</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="14">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14 15">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="14"/>
    <dbReference type="EC" id="1.6.2.4" evidence="14"/>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C230"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070330">
        <property type="term" value="F:aromatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06206">
        <property type="entry name" value="bifunctional_CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11068">
        <property type="entry name" value="CYP120A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000040">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF127">
        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 14" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 14" id="KW-0288">FMN</keyword>
    <keyword evidence="4 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="12 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0521">NADP</keyword>
    <keyword evidence="11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="17">
        <location>
            <begin position="506"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="18">
        <location>
            <begin position="682"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000209-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK85208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1078" mass="120101" checksum="07D56B4E8BB682EF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2H5</accession>
    <name>X0C2H5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2H5"/>
    <dbReference type="HOGENOM" id="CLU_2849813_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="65" mass="7508" checksum="A2186ADDCF49F7CC" modified="2014-05-14" version="1" fragment="single">MDEIIGHTRQTQDQLGKSHLSFVIKTTNHRWDLAKYFDRMVHWLDKFKGIGDVASSFDPVHAALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2N8</accession>
    <name>X0C2N8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Gem-associated protein 5 TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_18224</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658647">
        <property type="protein sequence ID" value="EXK77052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2N8"/>
    <dbReference type="HOGENOM" id="CLU_000799_0_1_1"/>
    <dbReference type="OrthoDB" id="7326421at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034605">
        <property type="entry name" value="PGC-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056421">
        <property type="entry name" value="TPR_GEMI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15528:SF11">
        <property type="entry name" value="FI18188P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15528">
        <property type="entry name" value="PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23774">
        <property type="entry name" value="TPR_GEMI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Gem-associated protein 5 TPR" evidence="8">
        <location>
            <begin position="66"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="321"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="433"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="529"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="681"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="819"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="488"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="538"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="685"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="724"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="738"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="836"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="862"/>
            <end position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK77052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="895" mass="99082" checksum="8061338AC7250F6C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2Y9</accession>
    <name>X0C2Y9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08329</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2Y9"/>
    <dbReference type="eggNOG" id="ENOG502SDAK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_918408_0_0_1"/>
    <dbReference type="OrthoDB" id="5106279at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936147" description="WSC domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="24"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="303" mass="31287" checksum="E52C71C886BE01F5" modified="2014-05-14" version="1">MFSHLLIAAFGVTAALGQTSYGEQFKYWGCATVDAAGFSNPVPLPNGILTPEACQDACAGHMFAAVSPDACRCGDDANAIKSVDEHSCNYPCNQDPNSPMCGGICPEGTPSISNLFIIEPAELPASEPVPQLDNPLNQPMSINAVPPSMAPQASFASDALPVATSSPLPGVPLPQSEAVQQPPVTSVTLPSPTSIPSDPPVASPDQPEQSPPQSTINFPSTLTQPSSVSLLAPAASAPDSTREVPGIPPKSQTEPSTSETLVTETGSLPSVAPSRVDVSESRRFEISMLPTIGGLLFMVIMAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3X3</accession>
    <name>X0C3X3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3X3"/>
    <dbReference type="eggNOG" id="ENOG502QPW5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5243398at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="865"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="841"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="925"/>
            <end position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="961" mass="103274" checksum="293C5692A4FF3977" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5R4</accession>
    <name>X0C5R4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658547">
        <property type="protein sequence ID" value="EXK78087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5R4"/>
    <dbReference type="HOGENOM" id="CLU_2333700_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="98" mass="11044" checksum="46C30BFCB6D3DD21" modified="2014-05-14" version="1">MACGSGPNGNPIPDVHDGVFIMDQILIIAMEWVALNIVPVKTFIVNTMKINYRYPIRTDFIGKCPENRIHCELLDPAVQRMWRQLSDIATSFATSIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C644</accession>
    <name>X0C644_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C644"/>
    <dbReference type="eggNOG" id="KOG2058">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005350_3_3_1"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000050">
        <property type="entry name" value="GTPase activating protein (Gyp3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="639"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="984" mass="108350" checksum="EFB475EE6606D820" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C696</accession>
    <name>X0C696_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C696"/>
    <dbReference type="HOGENOM" id="CLU_1896315_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="134" mass="15163" checksum="EF019856185E7A25" modified="2014-05-14" version="1">MPGSRHRQYTKGSHFTSGHIDTDKCSRRDQTRVPALHYDCAQYSRLPRSRNMVQCYIMYARVSGITGSHVLQHRTVRCTISFNAIVLCRLCSTAMDGWIEANKQGPEQTSGNGAEARAMPTRKVTGRFIRMPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0C819</accession>
    <name>X0C819_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_09164</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C819"/>
    <dbReference type="eggNOG" id="ENOG502RXSB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016574_2_1_1"/>
    <dbReference type="OrthoDB" id="4132249at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF20">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="524"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="642"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="642"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK87343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="669" mass="74570" checksum="586F45B89A4410E5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9B5</accession>
    <name>X0C9B5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sphingoid long-chain base transporter RSB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06554</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9B5"/>
    <dbReference type="eggNOG" id="ENOG502QU4U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033465_2_1_1"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF9">
        <property type="entry name" value="SPHINGOID LONG-CHAIN BASE TRANSPORTER RSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="275"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK91025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="42309" checksum="FFE449839167BE9D" modified="2014-05-14" version="1">MAGDCGSTCPASDGFYSYNPSVGGNAVLLVVFSLLALAAIYFGIRSRTYLFSLALTTGLFLEVLGFVGRILLHSKRDSQGHFFLFLFGTVLGPSLISVAIFIILPHILGIYGEPLCPFRPLVAGLVFWGLAAVTVLFELIGIVFTAYESNGVTRKQGAAITATGLAIQALSLIACTGLHFWFTLSLSTRRGTLDARHSQVYSSSRFKKFLLAMEMASALLIVYSFYRLVEFADGVSGDVFQNEAAFMVVGGLLPFLAAALLTAIHPGNAFADAWAPTSPRGIKRQSRPTPVQSPTPSGHPVHHLYDPDIRKQISPTSPKHRNSAGPPELPQGSMGLPAHPKPVPRPPSPRDPNAPRKGPPAPLNLAAVRASRNSCRAEQRGHAPKDMVPDGELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9R6</accession>
    <name>X0C9R6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">dTDP-glucose 4,6-dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658471">
        <property type="protein sequence ID" value="EXK79432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9R6"/>
    <dbReference type="eggNOG" id="KOG0747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055718_0_0_1"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048269">
        <property type="term" value="C:methionine adenosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048270">
        <property type="term" value="F:methionine adenosyltransferase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05254">
        <property type="entry name" value="dTDP_HR_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="DTDP-4-DEHYDRORHAMNOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491:SF4">
        <property type="entry name" value="METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD-like substrate binding" evidence="1">
        <location>
            <begin position="22"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="309" mass="34560" checksum="10521F4861800593" modified="2014-05-14" version="1">MSGIRTNGTNGTSGLHIRVPNRFLIWGGHGWIAGLLKDLLHHQGKKVYTTTIRMEDRDDVAKALEVFKPTHVLNAAGCTGRPNVDWCEDNKAQTVRSNVIGTLTLADECDKRGIHCTVFATGCIYQYNEEHPIGGPGFKETDAPNFDGSFYSMTKAHVEPILASFKNVLILRFRMPVSDDLNPRNFVTKISKYEFVVDILNSNTILHDLLPASIILAENKDTGVYNFTNPGAISHNEVLGLFKEIVRPGFTWKNFSIEDQARVIKAGRSNCQLDTAKLVKKMVGYGYEIPEIHEAYRQCFERMKAAGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9W7</accession>
    <name>X0C9W7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9W7"/>
    <dbReference type="HOGENOM" id="CLU_199215_0_0_1"/>
    <dbReference type="OrthoDB" id="4973898at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="76" mass="8281" checksum="4CADA4F1E9EB9410" modified="2014-05-14" version="1">MLTSKGDRCSKLPAKQWTGLARLLLEFFSAGFLGATMLGWSPSSSHKPGTQQQPSTMTYDLTATRMLVVDFGAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CA64</accession>
    <name>X0CA64_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_09049</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CA64"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_0_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="55"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="526"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK87709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="549" mass="60690" checksum="73995CA581B17771" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAA3</accession>
    <name>X0CAA3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08529</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAA3"/>
    <dbReference type="eggNOG" id="ENOG502S404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030994_0_0_1"/>
    <dbReference type="OrthoDB" id="4150019at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="130"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="461" mass="49719" checksum="83909250C5858FF8" modified="2014-05-14" version="1">MAIAITSQDCSKLYSLGAGNSWESTSSELPMIGVMSYHYPPLSPADNEMGMPPQGFMPSYTLPSQQLCSMTMVDPHAPSLGQDHGLDMKGSYSAPNNAALLASEAEEQQQNGNLGEKKRNKLGYHRTSVACGHCRRRKIRCITSPNDTQGRCINCIRLKKDCSFFPVDQGSIDDSRSKQTSKSSTGPKGSSATSSPATPINNPVEQPKKTKPPFVPSSKRPGPITVPKITEAEGVKGFPPQTKASGTSPTSMTPPEAGNQHPTSWIITAPEHSPTSSSNLSTPWHTYATGSPMSAQFSPFTSVNHSPSGWPPVNSEPVPQGDMDMAWGQFAPPTRSMSYGGEPLSSGHPSQYPLMAPGRQFERRPSALSDAYTTSMSGMVPGFDGSSMNTAVPFPPNAVPATNYAAWNQTQAYPGYTYVKNQETYGDDWSHERRGQDQQLQANSGQQVINNATMNAYQTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBA9</accession>
    <name>X0CBA9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_15459</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658453">
        <property type="protein sequence ID" value="EXK79972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502RXC9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004989_0_0_1"/>
    <dbReference type="OrthoDB" id="5089701at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF7">
        <property type="entry name" value="NMRA LIKE REDOX SENSOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="5">
        <location>
            <begin position="3"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="978"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="989"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK79972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1423" mass="159116" checksum="68D6CFA7F653BB33" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCV0</accession>
    <name>X0CCV0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_06115</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCV0"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF49">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="498"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="105"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK92230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="606" mass="68099" checksum="0D3F50F81188D1E2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDM0</accession>
    <name>X0CDM0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDM0"/>
    <dbReference type="eggNOG" id="KOG1203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025711_1_0_1"/>
    <dbReference type="OrthoDB" id="10254604at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF50">
        <property type="entry name" value="UPF0659 PROTEIN YMR090W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="10"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="264" mass="28444" checksum="D2ED8AAF85C5B474" modified="2014-05-14" version="1">MASHHVLLLGGHGKIAQLLTPLLLKRSWTVTSVIRTSEQTPAIEKLGAGLPGKLNVLVRSIEDVTSQDKALSILNEVKPDYIAWSAGAGGKGGAERTFKVDRDAAVHFINAAASVPTITKFLLISYLASRRSGASWWPAGEWDEYNEKVNNGVLANYYKAKIEADETLYKVSKKSPTLVGIDLRPGTLTDDPATKVEFGKTKSIAKNGVSREAVAEVASHLLAAYGVKNGWYDLLDGDEDIPAAVERVVRENVDAAEGEAIYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFF3</accession>
    <name>X0CFF3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05176</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFF3"/>
    <dbReference type="eggNOG" id="ENOG502SRJS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095045_1_0_1"/>
    <dbReference type="OrthoDB" id="6329284at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="12"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK92921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="169" mass="18683" checksum="4ED8F43832C90D68" modified="2014-05-14" version="1">MNDNNQDTPSAITGGCLCSAIRYTVNFNEEYPWPPISSACQCTMCRKWTSSLIAQFLVISPKQISPALGTFASFKEYMSSPGRFRGFCGDCGTSLTWRSADYTPIFDLYLGTLDEKYLVGDGVVAKTLATPNGTQYWMQNSIHGVTDVLKEGKKYSEEGPDGLRDENNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHH4</accession>
    <name>X0CHH4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_06876</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHH4"/>
    <dbReference type="eggNOG" id="ENOG502S3QV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043818_0_0_1"/>
    <dbReference type="OrthoDB" id="436519at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="76"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK90688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="359" mass="40644" checksum="C49901BECAB0E65B" modified="2014-05-14" version="1">MSGYLSMLGWAFLPNLATGWLQSIYYGFTIRAGDPKPAPGSARYNSHRRTIHILVVAAYLCYTIFEADYEQRRISSYYADLGVPLDAADREIKTRFRRLVAMHHPDKAGKDAGDSAAFFMHLKVASDTLQDTAKRFAYERFGPEIARWQKCVTIRDYVTRGVVSGILPHYVVAAASIYILGLFGYMEFGKYYRWLVLIALCVFELHTVTRPDFPPFVNAINAILTQFTSSPPYLPFQIISLARRLTITFYIALNQIGPLIAFMITGPEKSEEDDEKAMRQSLHRLEMLTKQLDGDAVRLLDMEMAPFKGDTDATSNLQGKMREWLVQNTIRADPMVRDAMGTSLRKRRVDAPAGAKGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHK8</accession>
    <name>X0CHK8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHK8"/>
    <dbReference type="eggNOG" id="ENOG502RIWF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_295115_0_0_1"/>
    <dbReference type="OrthoDB" id="3486565at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="267"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="300"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="573"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1026" mass="116230" checksum="276D770411E41683" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHL4</accession>
    <name>X0CHL4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHL4"/>
    <dbReference type="eggNOG" id="ENOG502S9K3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060150_0_0_1"/>
    <dbReference type="OrthoDB" id="2530521at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="323" mass="32715" checksum="F8D352F716121D57" modified="2014-05-14" version="1">MADFAPPSGPPPPKAPEVPAGWAVRWNEQYKEWFYVNIYTKQSQWEKPTAPVFPADDAAPAGPPPGYDQGNAPIPTDTKKNPYEDHRDQSAGGPSEDEDAKLAAKLQAEEDARARSGPGGPDVPAGYGASNSPYPQSNSPYPQNNSPYPQQQGGSSYPTELPPRERGAKSGGGFLGKLLGKGKQMAGGHQQGGAGGYGGSQGGYGGGYPQQQYYGQQPQGYPGQGPPMGYGAQPHYGGGYGAPGGYGGYGGAPGYGAPHGGGFGGGGRKPGGGGMGMMGGAALGAGAGLLGGAMIANSFDNDEQDAYQDGFEDGADFGDDGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHV5</accession>
    <name>X0CHV5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHV5"/>
    <dbReference type="eggNOG" id="ENOG502SQ7V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_24_0_1"/>
    <dbReference type="OrthoDB" id="4072826at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="37"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="227" mass="25760" checksum="C212A66B7CD6CDFE" modified="2014-05-14" version="1">MESTKPSSIDFVTVKTTLPVYPLPPNHERSTFRSERLSMRHMTEDDFGFLRALRTDPDGMKWSSQGGPDIEMEQTEKSLSLRLPPKDVERHDWVISLIETGEPIGLGGTCVWSSELGWPALGYIFLKEHWGKGYASEFMKVYLDKWWSLPRNEVELTVDKNTVLEEDGDVKQECISAVTMSENAPSQNVLKKAGFEFVSSWMEADTKDESQELTLHGFVARKGKVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHV9</accession>
    <name>X0CHV9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_04962</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHV9"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_3_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000061">
        <property type="entry name" value="MFS sugar transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="17"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="514"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="521"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK93751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="548" mass="60564" checksum="B75C6DFE342932E2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIE9</accession>
    <name>X0CIE9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIE9"/>
    <dbReference type="eggNOG" id="ENOG502S6F0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_997649_0_0_1"/>
    <dbReference type="OrthoDB" id="21418at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38645">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38645:SF1">
        <property type="entry name" value="YALI0F12243P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="243" mass="26282" checksum="639924761643E96B" modified="2014-05-14" version="1">MEPMRGVSGSMGKQPAQQESPEQLLDVFKAAALSVTKLYKISAAGQSKARADGYQDCLDDLLQFLDKEGMGLGDGEGWKIRKWATERLDGRESSSLNTESEDEVDKAETASSPELTRTAIPPHPANQVRTDSAPPSIPPVAEQPTPIVVPSQDNFTFQSSHPYPNIATLDLSDSRPHDDVPAPTRPTKTRLAGGPSRSCPRGPGHLVQRAGSKRKLNFEEIFDLGSLSGKDPFEKGGKRGRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIG7</accession>
    <name>X0CIG7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIG7"/>
    <dbReference type="eggNOG" id="KOG1695">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003953_3_0_1"/>
    <dbReference type="OrthoDB" id="5135333at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="246"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="796" mass="90581" checksum="9F64C36099F01760" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJA4</accession>
    <name>X0CJA4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aromatic prenyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tryptophan dimethylallyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJA4"/>
    <dbReference type="HOGENOM" id="CLU_1102833_0_0_1"/>
    <dbReference type="OrthoDB" id="5392033at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13929">
        <property type="entry name" value="PT-DMATS_CymD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033964">
        <property type="entry name" value="ABBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017795">
        <property type="entry name" value="ABBA_NscD-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03429">
        <property type="entry name" value="arom_pren_DMATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40627">
        <property type="entry name" value="INDOLE PRENYLTRANSFERASE TDIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40627:SF4">
        <property type="entry name" value="PRENYLTRANSFERASE ASQH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11991">
        <property type="entry name" value="Trp_DMAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00036">
        <property type="entry name" value="Aromatic_Prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="28276" checksum="5B49A657B95B7A88" modified="2014-05-14" version="1">MFWAFDLKESATTNKAYFFPGAVAHSVGKSTLDVVTDAISSAPGCQPESISAFASFARFVNERRYLNLEMDMLALDLVPIEKSRLKIYFRDRRTDFRSVTEMMSLGGRIHGADFDVGMRNLRNLWDTLLGTSGVPDDIPLPHNNHRTAGILYNVELRTNSTIPKVKIYIPVRHYAKNDSQILEALKGFLTDQASKLPDVAIDLNWAKRYSDCLYSIFGEEMLSNGLGVHTYIGCSIQSKGDLRVVAYVNPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJJ5</accession>
    <name>X0CJJ5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_12976</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJJ5"/>
    <dbReference type="HOGENOM" id="CLU_026314_0_0_1"/>
    <dbReference type="OrthoDB" id="2096480at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050631">
        <property type="entry name" value="PheA/TfdB_FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43476">
        <property type="entry name" value="3-(3-HYDROXY-PHENYL)PROPIONATE/3-HYDROXYCINNAMIC ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43476:SF5">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="3"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK82702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="622" mass="69511" checksum="7CFE1389A7277BAF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJR3</accession>
    <name>X0CJR3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJR3"/>
    <dbReference type="eggNOG" id="ENOG502RP7R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124041_1_0_1"/>
    <dbReference type="OrthoDB" id="2947043at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="16178" checksum="381E627906ABE2BB" modified="2014-05-14" version="1">MASASCHVDWTSSLNKYEKGFESIFIGGPETTQADLEGLFTQDYTSIVDGKRIEFPEFVEHIQHLRQVTTAIKVQVTHFLREGNQLAERHFVTAEFSNKPPSKYEVFLFATVDESGRIERLVETLRQTDGLEEHRDLGSARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0CK19</accession>
    <name>X0CK19_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fork-head transcriptional regulator 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_03610</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CK19"/>
    <dbReference type="eggNOG" id="KOG2294">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007090_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22701">
        <property type="entry name" value="FHA_FKH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000030">
        <property type="entry name" value="Forkhead box protein K2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881:SF1">
        <property type="entry name" value="FORK HEAD PROTEIN HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="110"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Fork-head" evidence="9">
        <location>
            <begin position="285"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="285"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="222"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="378"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="535"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="504"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK94765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="66881" checksum="EEEC55FF4B1D3886" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKE8</accession>
    <name>X0CKE8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKE8"/>
    <dbReference type="eggNOG" id="ENOG502SAJJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1740603_0_0_1"/>
    <dbReference type="OrthoDB" id="360540at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="142" mass="15959" checksum="6BC684A75F10880E" modified="2014-05-14" version="1">MHLTQTNYEEVESDCQNVPPTKFNTCFHTVEEIPAHESTNHLSRPSEAPYSFERWLPLVLKTRNLDAKVAQIVKLTRAEAKLVVAASGTSIITGEHNRAYQEDIQEEIIPHLSSLDFPAEGLFMRLDRCSPKDGRQAVPAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLN4</accession>
    <name>X0CLN4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11 12">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 11 12">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_06398</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11 12">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 12">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 11 12"/>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLN4"/>
    <dbReference type="SMR" id="X0CLN4"/>
    <dbReference type="OrthoDB" id="2115822at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.180:FF:000001">
        <property type="entry name" value="Endo-1,4-beta-xylanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018208">
        <property type="entry name" value="GH11_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033119">
        <property type="entry name" value="GH11_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF3">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00776">
        <property type="entry name" value="GH11_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00777">
        <property type="entry name" value="GH11_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 11 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11 12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0843">Virulence</keyword>
    <keyword evidence="5 11 12" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937270" description="Endo-1,4-beta-xylanase" evidence="14">
        <location>
            <begin position="20"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="15">
        <location>
            <begin position="34"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="217"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="226"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="241"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="270"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK91719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="295" mass="30858" checksum="CA441056DCD3C104" modified="2014-05-14" version="1">MVHFTSVFAGLSLVAGSLAAPSKEGLFSKITKRAGTPNSSGTNNGFYYSWWSDGGADATYTNGEGGSYSMEWKDGGNVVGGKGWSPGKARTISYEGEYKPNGNSYLSVYGWTRNPLVEYYIVESFGTYNPSSGATKKGTVEADGSTYDIFETTRTNAPSIDGTQTFQQYWSVRQQHRSTGSVDTGLHFDAWEKAGMKLGTHDYQILATEGYFSSGSSHMTVSEGASSGGGAGGSTGGDASQGGDSQQGGDVQQGGDASQGGNGQQGGNGNSFQQPGSENQPQQQEIDTGANEPCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLS4</accession>
    <name>X0CLS4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLS4"/>
    <dbReference type="HOGENOM" id="CLU_2306229_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="100" mass="11123" checksum="A9346149D6E0B5C3" modified="2014-05-14" version="1">MPFCTRAHNNATNEKYKEWLVPGGAYNKLGLIDSATAGRGWKSRGNEEWESIDKRFPPRGSGRAFRARPGVAAERPPVRPSLLSTDSWVATLRALQVPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM73</accession>
    <name>X0CM73_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05932</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502S5AI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001575_0_1_1"/>
    <dbReference type="OrthoDB" id="1074at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02656">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37327">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37327:SF1">
        <property type="entry name" value="MICROTUBULE INTERACTING AND TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIT" evidence="3">
        <location>
            <begin position="360"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="265"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="419"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="749"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="856"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="674"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="749"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="764"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="820"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="856"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="934"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="963"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK91929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1305" mass="142594" checksum="228D685540C7661C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN01</accession>
    <name>X0CN01_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YMC020W-like alpha/beta hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN01"/>
    <dbReference type="eggNOG" id="ENOG502QR2T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010834_0_1_1"/>
    <dbReference type="OrthoDB" id="5598028at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058934">
        <property type="entry name" value="YMC020W-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058933">
        <property type="entry name" value="YMC020W-like_ab_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47349:SF1">
        <property type="entry name" value="AER328WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47349">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26147">
        <property type="entry name" value="AB_HYDROLASE_YMC0-YMC35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YMC020W-like alpha/beta hydrolase" evidence="2">
        <location>
            <begin position="483"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="459"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="879" mass="95336" checksum="074F9A4755358E01" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN19</accession>
    <name>X0CN19_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN19"/>
    <dbReference type="eggNOG" id="ENOG502RXWY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057354_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000018">
        <property type="entry name" value="RNase III domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040030">
        <property type="entry name" value="Ribosomal_mL57"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28160">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L15, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28160:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="1">
        <location>
            <begin position="101"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="251" mass="27726" checksum="72F34B288E098E7A" modified="2014-05-14" version="1">MALQPCRSGLWRSRHAARTLMPCVRTYATDSTPESFRTKTPSSSGVVPRWSQTPAAMKAPLQLDWAKNPQNKVWTVNNDPKKLDEVYERLLGPGGSKLLPEELKWLAVTHKSFDQGRRGFNDRLALLGRMTLVMETTKTIVAQSPMGTPNFDDGFDRQPFVHPNLQSVDNLSIKGPKDVVGKERLSGLAAEVGLIDVVRWKPKQVQKLRASGADVVLNGAIMAIIGAISLQHGAVVASQVIRERILSRLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN87</accession>
    <name>X0CN87_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_05777</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN87"/>
    <dbReference type="eggNOG" id="KOG0730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_12_3_1"/>
    <dbReference type="OrthoDB" id="27435at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001025">
        <property type="entry name" value="ATPase family, AAA domain-containing 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF27">
        <property type="entry name" value="ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="258"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="515"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK92743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="753" mass="83081" checksum="AADFA1F8004CE646" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNB6</accession>
    <name>X0CNB6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acetyltransferase BOT5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11768</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNB6"/>
    <dbReference type="eggNOG" id="ENOG502S6KB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029797_2_1_1"/>
    <dbReference type="OrthoDB" id="21502at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051283">
        <property type="entry name" value="Sec_Metabolite_Acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896:SF69">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="60803" checksum="A3C0278E36F5448F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQQ3</accession>
    <name>X0CQQ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_05349</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQQ3"/>
    <dbReference type="eggNOG" id="KOG2839">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_5_3_1"/>
    <dbReference type="OrthoDB" id="2011998at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034431">
        <property type="term" value="F:bis(5'-adenosyl)-hexaphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034432">
        <property type="term" value="F:bis(5'-adenosyl)-pentaphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008486">
        <property type="term" value="F:diphosphoinositol-polyphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901911">
        <property type="term" value="P:adenosine 5'-(hexahydrogen pentaphosphate) catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901909">
        <property type="term" value="P:diadenosine hexaphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901907">
        <property type="term" value="P:diadenosine pentaphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071543">
        <property type="term" value="P:diphosphoinositol polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04666">
        <property type="entry name" value="NUDIX_DIPP2_like_Nudt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047198">
        <property type="entry name" value="DDP-like_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629">
        <property type="entry name" value="DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629:SF0">
        <property type="entry name" value="DIPHOSPHOINOSITOL-POLYPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="6">
        <location>
            <begin position="30"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK93164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="163" mass="18665" checksum="B90EF4ECFDEC0C3E" modified="2014-05-14" version="1">MSSSASGDSGGGRSMESRVGRSKQRYNTKGERLVAGIVPLTPDQNYVLLIQSTRRKGWVLPKGGWESDETCQEAAEREAWEEAGITVQITYDLGDIDEKRAPKSSKDRSRYHFFEGTVTSEYDDWPESHKRERQWFTFTQAWEALSTRPELQEALQRSTVNRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQV2</accession>
    <name>X0CQV2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sialidase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03555</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQV2"/>
    <dbReference type="eggNOG" id="ENOG502SCD5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_287852_0_0_1"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF68">
        <property type="entry name" value="GALACTOSE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00231">
        <property type="entry name" value="FA58C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937849" evidence="3">
        <location>
            <begin position="17"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="4">
        <location>
            <begin position="408"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="369"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="234"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK96551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1051" mass="111795" checksum="9C9CBBB51A7E16C4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS79</accession>
    <name>X0CS79_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS79"/>
    <dbReference type="HOGENOM" id="CLU_133371_0_0_1"/>
    <dbReference type="OrthoDB" id="5424209at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="181" mass="20741" checksum="1D23145C55663333" modified="2014-05-14" version="1">MQQISQGILQNAHTIAKKHKLLYIKDMDDQIYFKMRSGTPTLLVVAPWSSEKTPIWEKAVEGDIHVEIITPELRQTIYFGASNDASLHGNWDWVRAKVHDCLQSFQATRDRLTLIALFQYGVIPDPKGNPLTIYISADFDLDETCWHEGVVDIKNMLQGVEGWGYVQVHMGHNEGWQDLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSK0</accession>
    <name>X0CSK0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inhibitor of calcineurin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RCAN family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSK0"/>
    <dbReference type="eggNOG" id="KOG4019">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050705_0_0_1"/>
    <dbReference type="OrthoDB" id="17212at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008597">
        <property type="term" value="F:calcium-dependent protein serine/threonine phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019722">
        <property type="term" value="P:calcium-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12434">
        <property type="entry name" value="RRM_RCAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000503">
        <property type="entry name" value="Calcineurin binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006931">
        <property type="entry name" value="Calcipressin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10300">
        <property type="entry name" value="CALCIPRESSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10300:SF14">
        <property type="entry name" value="PROTEIN SARAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04847">
        <property type="entry name" value="Calcipressin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="27974" checksum="FA1409CC461B0157" modified="2014-05-14" version="1">METSPQHSRSSSSASRRSNLTLDLSNIPPMTPPTPPSNTLLFTNLTDPAIFLPENLQVIRDLITHSAPIHAFAPLKSFRRIVVSFFDEQAAIAVRQVWDNEAIMGQQCRVYFGMPTPVDKRDEHLALPDAGKLFFISPPPSPPHGWEMRLEDAPNKLVHAEDLADALAKLHHRPGPMDEDQDSPVTPPDSALPGRTRSRSSTLIYKPEDSASTMPAVIVDDMTDEPEEVSPVEQSKPILAHTARPPVELMHHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTC4</accession>
    <name>X0CTC4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTC4"/>
    <dbReference type="eggNOG" id="ENOG502S9CJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014758_0_0_1"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="530" mass="58534" checksum="9117CECDA7B6B9E2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV28</accession>
    <name>X0CV28_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4 13">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_09995</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a quinone + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="4 13"/>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV28"/>
    <dbReference type="eggNOG" id="KOG0042">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015740_4_1_1"/>
    <dbReference type="OrthoDB" id="264015at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.870:FF:000001">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="entry name" value="Alpha-glycerophosphate oxidase, cap domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985:SF15">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00977">
        <property type="entry name" value="FAD_G3PDH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00978">
        <property type="entry name" value="FAD_G3PDH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="5 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="14">
        <location>
            <begin position="86"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-glycerophosphate oxidase C-terminal" evidence="15">
        <location>
            <begin position="500"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK86342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="679" mass="75162" checksum="BD199B7A51817101" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV68</accession>
    <name>X0CV68_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_03832</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV68"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_0_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000017">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF1">
        <property type="entry name" value="GENERAL AMINO-ACID PERMEASE GAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="41"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK95178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="536" mass="57877" checksum="2662DB813C032711" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWM2</accession>
    <name>X0CWM2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Protein FMP32, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_03883</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CCDC90 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWM2"/>
    <dbReference type="eggNOG" id="KOG3156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063283_0_1_1"/>
    <dbReference type="OrthoDB" id="889336at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.340:FF:000018">
        <property type="entry name" value="Mitochondrial protein FMP32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024461">
        <property type="entry name" value="CCDC90-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360:SF1">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07798">
        <property type="entry name" value="CCDC90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="35"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK95259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="29337" checksum="4EA08B6EB3A99306" modified="2014-05-14" version="1">MAVPSVAAAEMLPRFLLPRLSWGAPLSVSRAPRPFASIPSRDQRRSFASIQAGPVPRRRSPQAESPIIKRAFHATTIRQRDHHFDTLKFVKRLQGEGFTEEQSAAMMKVLNDVIEESIQNLTRTMVLREDAAKATYTQKVDFAKLRSELLSADSTESNTTRTAHERLTNDIAKLSNRLRDEISRTQASVRLDLNLEKGRIREEAVGQELKIKETETKIEQEVAALREKLEQVKFQTLQWLMGVCTGFAALLLGAWRLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYC7</accession>
    <name>X0CYC7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYC7"/>
    <dbReference type="eggNOG" id="ENOG502S91F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026999_0_0_1"/>
    <dbReference type="OrthoDB" id="5421421at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="518" mass="58381" checksum="38191E258183065F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYX8</accession>
    <name>X0CYX8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation-transporting ATPase</fullName>
            <ecNumber evidence="13">7.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_00137</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.-" evidence="13"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001828_0_0_1"/>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015662">
        <property type="term" value="F:P-type ion transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07542">
        <property type="entry name" value="P-type_ATPase_cation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000032">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000119">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000057">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000068">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047819">
        <property type="entry name" value="P5A-ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047821">
        <property type="entry name" value="P5B-type_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF8">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12409">
        <property type="entry name" value="P5-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="578"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="614"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1103"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1127"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1167"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1214"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1244"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1283"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="domain" description="P5B-type ATPase N-terminal" evidence="17">
        <location>
            <begin position="196"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="15">
        <location>
            <begin position="432"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="16">
        <location>
            <begin position="1127"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="751"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF12409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK99700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1337" mass="149972" checksum="E4CCDFC4E70EF066" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYY7</accession>
    <name>X0CYY7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYY7"/>
    <dbReference type="HOGENOM" id="CLU_017861_0_0_1"/>
    <dbReference type="OrthoDB" id="4161727at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK96079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="575" mass="65616" checksum="1DCA69AD4DB32936" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ23</accession>
    <name>X0CZ23_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01946</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ23"/>
    <dbReference type="HOGENOM" id="CLU_019706_0_0_1"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058664">
        <property type="entry name" value="ARB_00930-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF97">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26335">
        <property type="entry name" value="ARB_00930_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937524" evidence="1">
        <location>
            <begin position="25"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="99"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-like ARB-00930-like C-terminal" evidence="3">
        <location>
            <begin position="429"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK99416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="574" mass="62189" checksum="9962E0810EF78D97" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0U9</accession>
    <name>X0D0U9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein HID1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0U9"/>
    <dbReference type="eggNOG" id="KOG2226">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007392_0_0_1"/>
    <dbReference type="OrthoDB" id="432953at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000138">
        <property type="term" value="C:Golgi trans cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026705">
        <property type="entry name" value="Hid-1/Ecm30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575:SF12">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12722">
        <property type="entry name" value="Hid1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="655"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="879" mass="98920" checksum="8DC6308EE762827C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0V6</accession>
    <name>X0D0V6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0V6"/>
    <dbReference type="eggNOG" id="ENOG502RPZR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_809012_0_0_1"/>
    <dbReference type="OrthoDB" id="5244495at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="351" mass="39463" checksum="E493A9AA7B56339C" modified="2014-05-14" version="1">MGGKTWSVDEERMLWEVVVPRSVAAANPADRGMSWEQCAQYMNDNAGDIAQRNYTKNMLYEHHYQNIVKGGSSPNAGPFVERHLCLIEWYKNHRSPPPASSSPVPRPPRNPELTALLSEQSKPKRRRDKNAAKTRVAENRNALPTIDEDGPGPGPSGSGTSSVPYVRSFAPYDWAQQQSFEENQSPPDDPRAKYALDFRPLPRTVRAARPGGNFLSRPMEKVEGGLWRLVPETRENENLGESMSMVPRNSNVQARHSRAQEESSWTRPYTGPPQRSPQGPQGGSLPSIRQTFPFINFRQPPNSVPLRETSHQPGKRGYSGGQDQNQAPKRRRLPDHPVPRQSNQQPPSQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1G0</accession>
    <name>X0D1G0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mediator of RNA polymerase II transcription subunit 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_08330</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 22 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1G0"/>
    <dbReference type="eggNOG" id="ENOG502SD63">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109022_0_0_1"/>
    <dbReference type="OrthoDB" id="203279at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.160">
        <property type="entry name" value="Mediator of RNA polymerase II transcription subunit 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009332">
        <property type="entry name" value="Med22"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06179">
        <property type="entry name" value="Med22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK88517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="18296" checksum="4BF45672F6253046" modified="2014-05-14" version="1">MDKHQKIISEILRSYRDLMNCVTVNGMDKEKQGDYEAQANKLNYRDPDTMAAAGLRTQRKFDELYESIKELLALTRTIKELWVFGPVDRADEHRKEKEEQIDRDVAEITTLFNKIDANAMRELAEKNGGTWESQGEAAATAAAAAAAPPATTTAQAPEAPAPTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2C1</accession>
    <name>X0D2C1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">magnesium chelatase</fullName>
            <ecNumber evidence="1">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02518</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="1"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2C1"/>
    <dbReference type="HOGENOM" id="CLU_034390_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.80">
        <property type="entry name" value="Magnesium chelatase subunit I, C-Terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052041">
        <property type="entry name" value="Nucleic_acid_metab_PIN/TRAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11603">
        <property type="entry name" value="AAA FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11603:SF132">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ChlI/MoxR AAA lid" evidence="4">
        <location>
            <begin position="272"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="84"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK97259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="366" mass="39746" checksum="4CFBAF7F13DB6170" modified="2014-05-14" version="1">MADDGLLDKVHALSDLELALLLCLISREHCLVSTPSDAIDDLIQELQLVATKTFGLSWVVIDCTPSTTLEDFASALLLGNAASPSSHSPTASRHPDSYFTSRPSTSHPRTPLSPLTPSGAFTSRIANVVFAKNLDRAPQAVQIQALELLRTRRIFTRTSVQTAPKQFVFIPVLEAASGGEARVTAHLNDFLYIAYWHNPEDGFVNLEEADGGNDADTASTGSVVKRGPGEETSSDPPLIVESDISYLGTLSKEAQVDVEIIRYQMNIVSFLRMHRAVAGGISPTATKHFGQLMRCLAALHRLDFVTPALVGLAARKVYLHRIQLTPPEKERSMQWGSRLEAVEALLEDVGPEDVIEDVLGMVTAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0DA01</accession>
    <name>X0DA01_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <ecNumber evidence="3">3.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3-hydroxyisobutyryl-coenzyme A hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00581</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DA01"/>
    <dbReference type="eggNOG" id="KOG1684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_22_0_1"/>
    <dbReference type="OrthoDB" id="1737613at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000026">
        <property type="entry name" value="3-hydroxyisobutyryl-CoA hydrolase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004127">
        <property type="entry name" value="PRK05617.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="7">
        <location>
            <begin position="70"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL00384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="504" mass="56016" checksum="FBAA7697D43592CA" modified="2014-05-14" version="1">MTFRTLTVRAGASANVASRSSPRIFNMVQQSKILSSSLGARQLSSEATNIREKRNDDPNDVVFESKYGLRTVMLNRPKKLNSLNASMIRKIVPRLIEWEKSDLANVVVMKGAGEKALCAGGDVAALAKLNSESEDGWQKSAQYFALEYKLDHYIATYKKPYIAFMDGITMGGGVGLSTHAPFRIATEKTVFAMPETTIGFFPDVGASFFLPRMNGSVGTYLALTSERLTGPNVFYSGIATHYLHSTSLPDLEARLAELRFRDSDGLPERLALINQTLEEFCTGLPYDQPITLSGEIRQAIDRCFNKHTISEIIAALQAERGPTEEWAQKQLKTLHKRSPTAVHVALRQMRIGGEWDIAETFKREHQIATKFMQHPDFTEGVSALLIRKEAPKWQPESLEAIGGTNVAKPFFEYDSNNELALFTDRTFKEYPHRELGVPSEKEIEQVLSSGTYTQEQLANKIVSSRNGRQGIAEVAGEIIARKTAVDDQGKAVWMADESLPGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCA0</accession>
    <name>X0DCA0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCA0"/>
    <dbReference type="HOGENOM" id="CLU_196951_0_0_1"/>
    <dbReference type="OrthoDB" id="5034517at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL00730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="63" mass="6935" checksum="9687BF54602A0414" modified="2014-05-14" version="1">MVQALNIEGIDSSIVLLVAGSGLAEPGVDILVQQRIARQKRGFRRVGFVLFREPPTTPNHPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0DG40</accession>
    <name>X0DG40_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DG40"/>
    <dbReference type="eggNOG" id="KOG0747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054225_0_0_1"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08946">
        <property type="entry name" value="SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="333" mass="37034" checksum="9743DD65F4593608" modified="2014-05-14" version="1">MAYNVLVTGSSGHLGTALMLSLPAFGFTPLGIDILPSENTTHVGSVSDREFVTSLLQKHPIQHVLHAATLHKPHVESHSKQDFIDTNITGTLVLLEEASKLGAQIESFIFFSTTSTFGAALSPKPGQPAAWIDETVVPIPKNIYGATKVAAEDLCFLVQKQTGMPVVILRTSRFFPEQDDDEDRRAAVSDDNLKVLELAYRRCDIEDIVRAAVCAMKKAREIHFRKYIISAPPPFPNDADTLAMLDRDPKQVFEAVAPECVQVFKDKGWSHLKRMDRVYDSSKAVEELEWKPEFTFKKVVELVGEGKEWKSELTGKVGKRGYHAVSHGVYTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DGE5</accession>
    <name>X0DGE5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">EDC4-like protein pdc1 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_04815</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat EDC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502T19D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003635_0_0_1"/>
    <dbReference type="OrthoDB" id="21128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000817">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055393">
        <property type="entry name" value="Beta-prop_EDC4L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045152">
        <property type="entry name" value="EDC4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598:SF5">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24106">
        <property type="entry name" value="Beta-prop_EDC4L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EDC4-like protein pdc1 beta-propeller" evidence="8">
        <location>
            <begin position="512"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="133"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="294"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="997"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1326"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="370"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="302"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="997"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1057"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1362"/>
            <end position="1375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK93552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1592" mass="175339" checksum="5D9497F217FEC92F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0DPL9</accession>
    <name>X0DPL9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03349</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DPL9"/>
    <dbReference type="eggNOG" id="ENOG502RGNJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016357_0_0_1"/>
    <dbReference type="OrthoDB" id="4115389at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056669">
        <property type="entry name" value="DUF7767"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057940">
        <property type="entry name" value="Tri-helical_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24962">
        <property type="entry name" value="DUF7767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24465">
        <property type="entry name" value="Tri-helical"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Tri-helical" evidence="3">
        <location>
            <begin position="211"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Tri-helical" evidence="3">
        <location>
            <begin position="304"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7767" evidence="4">
        <location>
            <begin position="580"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK96237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="676" mass="77205" checksum="D86C4785C8F1FA0E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0DUI9</accession>
    <name>X0DUI9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial phosphate carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DUI9"/>
    <dbReference type="eggNOG" id="ENOG502SA1K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177926_0_0_1"/>
    <dbReference type="OrthoDB" id="9992270at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40135">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40135:SF1">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9294" checksum="5B3279B388030D53" modified="2014-05-14" version="1">MIITRALSITNFVIAGSALSFQVGVLYPWHKQLDDGFEELKKEHLRVLQAVESKVQQTRDTAVLEESRNSVRGLLGNLAAWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0DWK9</accession>
    <name>X0DWK9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_01442</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 12">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DWK9"/>
    <dbReference type="SMR" id="X0DWK9"/>
    <dbReference type="eggNOG" id="KOG2906">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093932_3_0_1"/>
    <dbReference type="OrthoDB" id="282152at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10509">
        <property type="entry name" value="Zn-ribbon_RPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034014">
        <property type="entry name" value="Zn_ribbon_RPC11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF12">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="13">
        <location>
            <begin position="66"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="10">
        <location>
            <begin position="5"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK98572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="110" mass="12735" checksum="E21331541D9F4834" modified="2014-05-14" version="1">MLLFCPHCANILTVSLTNTRTNRLECRTCPFEHHITEPVFSRRMYERVEKEDVFGGPGAWDNAQKGRVQCPNEGCEGDEAAFFQVQIRSADEPMTSFYKCMTCGHRWREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0E0F9</accession>
    <name>X0E0F9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E0F9"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="322" mass="35614" checksum="115CA9EBBF71F799" modified="2014-05-14" version="1">MSFLLNMIHGRFTTIPPQEEDCTDKVVIITGGNGGIALEAARHFTQLSAAKVILACRSLEKGDHAKKDIEETSGKQNVVEVWHLDLASHDSIREFADRVNKLDRLDVFINNAGLLVFKRELIEGHESMLSINVISTALLTLLVLPALRQTSNRFNIIPHIVIVSSDAAFEGRLPVQEPNFIKALDEQPSVLEHYSKTKLVQLIFMTQLAKAIEASGKGYIVVNGVHPGFCSTPLFDNTPWPFNLIFKGLLALFGRTPEVGSRALLAGAFADESLNGKFMSNGAFHELPKIMQGDEGEEMCRKVWEELISILEEIEPGVTKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0E0Q5</accession>
    <name>X0E0Q5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_00302</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E0Q5"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028814_0_0_1"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000260">
        <property type="entry name" value="Spalt-like transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002157">
        <property type="entry name" value="Transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF142">
        <property type="entry name" value="ZINC FINGER PROTEIN 384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="225"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="255"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="125"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="133"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK99927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="494" mass="55076" checksum="882854C124FCF27B" modified="2014-05-14" version="1">MALAAQSSDAPNWGRWSQQLPGDYTMMASPHMLPFDSRAAGPLQRPVMAPYMVQPSYSSGPVNSLTAPHYQVPNPYQFGGYQGPPTPPHHSTPFKMEYNDRRPMGHDNDHGRMPSYSREMKYTYAEQAPSPARSDSQASTVRSSGTNPSMGSKTITSNETLNPGDQINFETEVDELMKAIQRKADLQVDTVQQPLTPGMSPVSEASFESQGTPGPMDSKTARKRYRCDGPNCQKSFTQKTHLDIHRRTHTGIKPYNCDFPGCDLTFSQLGNLKTHRRRHTGERPFACDKCDRHFAQRGNLRAHLQTHQGLKPFICILDDCNKTFSQLGNMKTHQNNFHKKTLKKLTMKFANIIASGEEVSEADRELFEYFAAHYKNSNKGIKGRGKARTVADRKAKASQSPPANTMTAVPQYPLPQIAPTPVTPHGLPVSGSLASYSVTRGQPGPINHMSRQTHTGGYEVYDIQGHHHIQPPNNNGMLYETGSTREMAYHGRMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B133</accession>
    <name>X0B133_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979791">
        <property type="protein sequence ID" value="EXK75820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B133"/>
    <dbReference type="HOGENOM" id="CLU_2413364_0_0_1"/>
    <dbReference type="OrthoDB" id="5429923at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="92" mass="10439" checksum="7A6F5123227DF5B3" modified="2014-05-14" version="1">MATPWPQDEIWRTDYREHATNLSKYLQKALSAIDSGNGQPIASHGVRVALIGALYLIVKIQSTPDLGHISEIWTGLDREVWSLLERQWTIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2J4</accession>
    <name>X0B2J4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979673">
        <property type="protein sequence ID" value="EXK75976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2J4"/>
    <dbReference type="HOGENOM" id="CLU_150796_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="111" mass="12238" checksum="9DAADAEADDAED54D" modified="2014-05-14" version="1">MKTEFQLELTKLSDRMADEVARATAQVAQELSQVRDQLTQLDTLIKTETPRSSVQTYAEAARMAPTSMSSQSSSAVRSATPEAVFCTVDTSRVREDHIGDATPTMIRKTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0B343</accession>
    <name>X0B343_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylinositol-specific phospholipase C X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979483">
        <property type="protein sequence ID" value="EXK76560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B343"/>
    <dbReference type="eggNOG" id="ENOG502QWJU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031469_1_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF143">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C X DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936125" description="Phosphatidylinositol-specific phospholipase C X domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="59010" checksum="68A09BC9A357FA65" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4Y6</accession>
    <name>X0B4Y6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,5-lactone-forming)</fullName>
            <ecNumber evidence="3">1.1.1.179</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">D-xylose-NADP dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_18458</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22000"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15867"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.179"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.179" evidence="3"/>
    <dbReference type="EMBL" id="KI979443">
        <property type="protein sequence ID" value="EXK76811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4Y6"/>
    <dbReference type="HOGENOM" id="CLU_023194_5_2_1"/>
    <dbReference type="OrthoDB" id="6417021at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047837">
        <property type="term" value="F:D-xylose 1-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050984">
        <property type="entry name" value="Gfo/Idh/MocA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604">
        <property type="entry name" value="OXIDOREDUCTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604:SF105">
        <property type="entry name" value="TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="48"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="7">
        <location>
            <begin position="162"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK76811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="393" mass="43733" checksum="42706EA5B33DD555" modified="2014-05-14" version="1">MAMVLQITTFLQQWLESRPSVKEGPKSSDPVRFGILSTAMINPAGLIHPVETHPNAVIKAIASRDVRNAQKAAKTYKIEKAYGSYEELLADPEIDAVYISLPNGMHAEWAKKALSAGKHALIEKPVSSNGDEAASIFDAAKENNKVAVEAFHWRYHPAAHVVKSLVDSGRYGRVLSTCARMTTPAGSIPKSDIRWQWDLAGGSLMDMTYTVSATRYILGAETPVNVEFAKARPLKGDGRVDEAMEARLQFETDGGLVQSDIKTDMSQSFAGRLVPRVWELPSIRIELEHATIYYYNFMMPHIYHYIQVTDKQTGQTHTQKHYSFGPSWGPRSEPWWSTYRYQLEAFVDKVTGKEPAHWISPEDSIAQMRTLDAIYVKSGLGKRPSTASAAKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBI2</accession>
    <name>X0BBI2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979767">
        <property type="protein sequence ID" value="EXK75849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBI2"/>
    <dbReference type="HOGENOM" id="CLU_1219721_0_0_1"/>
    <dbReference type="OrthoDB" id="4761017at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="227" mass="25762" checksum="D10476D7088C2117" modified="2014-05-14" version="1">MASITCRVTDPAFTGIQGIYASLNCKDHHGNIISRYESFSDDDGNIRYWFRLSLGDMSIDPKPEIVDTLQFPAISMTFLPGIREPCFPWRSIHTELQLVANGQHEFILILNEHSASYQIHHALSSPLEAQMEWERTIKEHEMTALHEEPTRSPSPLRLPSPVITPQTGRGIKRKLFCEGEETSLGSNYIQSTKRRGVTRRNKNSGGVKRRNNAASKRRMTPDSDDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCB2</accession>
    <name>X0BCB2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658472">
        <property type="protein sequence ID" value="EXK79421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCB2"/>
    <dbReference type="HOGENOM" id="CLU_088455_0_0_1"/>
    <dbReference type="OrthoDB" id="5059594at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="315" mass="35277" checksum="611C14916140E9D9" modified="2014-05-14" version="1">MDFDIQLSKLEELRSNLAEDPTLTPSQEKSLSTTIELIKERQADRSKYSEAKRSRRKSARTLLSTIQERLGPVILFLCSTALSINKLYQINSQATTFISELDAWKNNVEFSRDIVDLAERHLTVDLLSCLGSDEAHTRLLKRGAHFDGGTAKRLRTEPSTPKNVTIPTYHGVLELATQQPSTRTPTDAHDGDSHGETGRNKEGSEDSDDSDDSDVGEVESAEALQDHSHSAPKDDGDSPIFVMSQNFPELTRVVQLYANVYQLRDMEVVRVIASQRENFTARLTVPHIPGATPFITIHCPRTLATEYVTRKQVTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD41</accession>
    <name>X0BD41_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658463">
        <property type="protein sequence ID" value="EXK79711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD41"/>
    <dbReference type="HOGENOM" id="CLU_663998_0_0_1"/>
    <dbReference type="OrthoDB" id="4835412at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="414" mass="47258" checksum="B900CAA00A91C2C7" modified="2014-05-14" version="1">MEVNANNSTSKFCFVASNIYEKLHKFQDFPMGTVKKIYLTEIFSEKDPPFHLVFSQDSIKKDDDDRASHCVRARDLSPSLEPERDTQNQSKGQNGDSLPRINLILGKVYIIYWADSEQLFARLLLPFDNPEFVTGESAEQMGLPRNMPSCYQHDTLSKSFSLTLDYEDNGRKCFEPYFPMVFFDGVKFPSKSSVAWAYIDCIQEWDEEKAQTIEHSQQAINYVKEQAKSQTRHYGFDDEILDSETDDGKRSYSLGGLTNMGLCCRDQFSQLPSRLPSTNLQPGAGESDREIILETQEEQEVSIGQEKPASLRGPSKDCLSSIESKDLLNESLDLEQQFLQFEQQVIDNPPASNRHNIIQATQMASICMKGAQEGSQTQQSIITWRLPYREASQYQLSYTDMSRISSLPQKHQMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDH2</accession>
    <name>X0BDH2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658455">
        <property type="protein sequence ID" value="EXK79866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDH2"/>
    <dbReference type="HOGENOM" id="CLU_1384237_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="197" mass="22819" checksum="B1D157FE69FD17EB" modified="2014-05-14" version="1">MVQTVPMFMEYTTGVRHKKHGTRSPSGLTRGTPYNTNTQSHLACGVWVNDFQHGFFAWNNRHKDTPQTSFFKLLGSSSNAKHMVNCEKKLNNLKGTLWDFNEPIGKDNWRDNYSATDDNTIRHALEQLILVKQIFPYLRKDDINTKLKDVNKEVIALLDEFDALYQSQYDANPLGLSTIWKDFIFKLLTNLQQFAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDY9</accession>
    <name>X0BDY9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_18598</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979464">
        <property type="protein sequence ID" value="EXK76664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDY9"/>
    <dbReference type="HOGENOM" id="CLU_009123_7_0_1"/>
    <dbReference type="OrthoDB" id="5062167at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK76664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="279" mass="32146" checksum="8B8382DAE7F67BF0" modified="2014-05-14" version="1">MAVFAHFIDQLGHQQSRLLALRRQSGAHSGENLAGSLVDIVHEWEIEGRVGYAISDNMAANDTCPLDAMLWAHAQSLRASLSLWQRLFEESTAELEVVMNIETRWNSTYMMIERALRKQTDIRAFLFAIQEEENEARRIPADDILSSEDWRVLGEVNEILKPIYLQMMRTQGWGKGDSHGRLWEVLIGMEYLLEHFEDWKVFYSEVAAETVGETHLDAAERIATAPANFRERNSRPSRVRRLPARFDEDEVYALPQRSQPTRFIESALPLHSRVEYSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BET3</accession>
    <name>X0BET3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658618">
        <property type="protein sequence ID" value="EXK77348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BET3"/>
    <dbReference type="HOGENOM" id="CLU_2049789_0_0_1"/>
    <dbReference type="OrthoDB" id="4996284at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13684" checksum="38E7FA6CEA94C199" modified="2014-05-14" version="1">MAIKPECSTVPACNSGRHKPSEAPPRRTIEKRHDTQFNDTFTELRDSISSMRVVMAKEGEESAMKDPQEVTPKLIGDEEAIICMAREYIALLEERNRSLVEEHTVLQSTIAAFEMLFPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF24</accession>
    <name>X0BF24_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979418">
        <property type="protein sequence ID" value="EXK77084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF24"/>
    <dbReference type="eggNOG" id="ENOG502S3UW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066707_0_0_1"/>
    <dbReference type="OrthoDB" id="63935at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF50">
        <property type="entry name" value="UPF0659 PROTEIN YMR090W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936881" evidence="2">
        <location>
            <begin position="21"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="263" mass="29323" checksum="61D989DBEDCBD80E" modified="2014-05-14" version="1">MAVKAAFIGACGATLRHVLAWTLLDGHKAAALVRDHSKLKKILLDLGVSEKIQQSQLIVVEGSSRDVSTVRNLLLNDPEIIFSGITSTWKLRFNPFHPIAMDDASITGDSAAAVMQALKDLVSTNSITNLPIYAPISSTGHGSRRDQPRSLMPLYWWLLKEAQADTAVLERVTREAATQKQSCLGGYVMLRPPLLTDGEMKGTKEVRVGWIWEDDIFRKSDEQETGVKVGYTISRMDLARWMFEELIQGDFRSWNGKCVNVTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFU0</accession>
    <name>X0BFU0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_17614</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658584">
        <property type="protein sequence ID" value="EXK77688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFU0"/>
    <dbReference type="HOGENOM" id="CLU_299968_0_0_1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00306">
        <property type="entry name" value="Peptidases_S8_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056002">
        <property type="entry name" value="DUF7580"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24476">
        <property type="entry name" value="DUF7580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="DUF7580" evidence="9">
        <location>
            <begin position="288"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="764"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="80"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="770"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="810"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK77688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1077" mass="120898" checksum="502E27A383F6BE6F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFX6</accession>
    <name>X0BFX6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_17905</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979391">
        <property type="protein sequence ID" value="EXK77389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFX6"/>
    <dbReference type="HOGENOM" id="CLU_038712_1_0_1"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF22">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G11480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="128"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK77389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="421" mass="47698" checksum="401D79260261B1B0" modified="2014-05-14" version="1">MEATELVENKPTARPFQCGWRSCTKSFKRKSDLQRHYRIHTNERPYACSISGCGKTFIQKSALTVHIRIHTGEKPHQCEHNNCGKRFSDSSSLTRHRRIHTGARPYKCTYDGCSRSFCRKATMDEHQRRSHQHGMNPNDILQDFSSDSEDNEPPLTPQPSAMTWSPRDIVSMDQAIPDGPIHRPPSYADFDQPVHGQHTPHQYDNRHGISSNAPRKSHGQPLLGYHVGAPTPRQTMTTPGQIYHIPERGNPGILTMSNTARPHQQLPHQVERPPTELLYPTLAIAAPTRTSPRTFSTKSVPSSGVQECLCKYLLKHEPEYAQADTQQSIIPFQQYIHNLISQPQQPVTSQAQAIHRLAAKHSPRISAQVQEENWSNYVLSTEATTIRHLPAYGNADYDPYEAKIEFDNPLMQLQSRSLASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BG06</accession>
    <name>X0BG06_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17528</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658574">
        <property type="protein sequence ID" value="EXK77773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BG06"/>
    <dbReference type="HOGENOM" id="CLU_3406451_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="30" mass="3311" checksum="7961E15679483320" modified="2014-05-14" version="1">MNDVVNTSSGFNTCAICLGLMEDKDIIRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGK1</accession>
    <name>X0BGK1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658432">
        <property type="protein sequence ID" value="EXK80946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGK1"/>
    <dbReference type="HOGENOM" id="CLU_115491_0_0_1"/>
    <dbReference type="OrthoDB" id="5096009at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="141" mass="15120" checksum="510157047F144E0D" modified="2014-05-14" version="1">MKATETAVLDFWNSCNDFTQYAVSSFSLADQFTAAGEVSLQGIISMLTGQAYSQPGSENDFEFKGLAQSASEMLLNLSQLANQKASSIQGLTASIASQASKVQTTRKEVDAVVKKFGLLSGDRYISTLDETLSISVSNRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH98</accession>
    <name>X0BH98_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_17099</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979365">
        <property type="protein sequence ID" value="EXK78203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH98"/>
    <dbReference type="eggNOG" id="ENOG502RMHE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015161_2_1_1"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF6">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="77"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="570"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK78203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="653" mass="73993" checksum="ACF369C306FBA078" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHF1</accession>
    <name>X0BHF1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658559">
        <property type="protein sequence ID" value="EXK77904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHF1"/>
    <dbReference type="eggNOG" id="ENOG502RVM5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014954_0_0_1"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="141"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="861" mass="98032" checksum="051664434DC45400" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI22</accession>
    <name>X0BI22_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979358">
        <property type="protein sequence ID" value="EXK78508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI22"/>
    <dbReference type="eggNOG" id="ENOG502RPPQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_813916_0_0_1"/>
    <dbReference type="OrthoDB" id="5090566at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="381" mass="44085" checksum="A837EFC4EEBB7A68" modified="2014-05-14" version="1">MSGKITSKFTLGISANLCSVISIIIYCLFPFFLLAFDTATMDYKDCKLEEHFDDMEIELIHQVDNAKHHLETTASAFWQAYLQRNFPRPWLVLCEQGPDGSLRRVDMKVIYYNSHGRNFSPVMLVEVKRKKGSMHEVEEQGLDAALKAINSQNLTGMYVITAIGLRYRAWYLSREERELQPLHGSIEKASWEYLHVKQQAGVLNLEETIRLIKGEMPMRQAGVVPSQHIELENILRAEASHIQEGYSVEQAGSARDDQGNEAPCYPSTTYYEQPSEQTDAQWSDPMDVEARAESSGEDDEPSQAEDSKGKKPRKERTIVNVRVTLIPHKLRKDECEFRDTKKIKQTTLRSDWKEKHDGSKTYFEFKGKNHRYRCEKFEYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI75</accession>
    <name>X0BI75_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI75"/>
    <dbReference type="HOGENOM" id="CLU_3279489_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="41" mass="4748" checksum="A5C752A6E94549BB" modified="2014-05-14" version="1">MKIEENILYKKTIPSFGTEDGFKKRPSKRHSKERHSKTTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIF4</accession>
    <name>X0BIF4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13711</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658419">
        <property type="protein sequence ID" value="EXK81955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIF4"/>
    <dbReference type="eggNOG" id="ENOG502QPZ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039534_1_1_1"/>
    <dbReference type="OrthoDB" id="507128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935743" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="3">
        <location>
            <begin position="35"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="480" mass="51828" checksum="8E3A947F2E4EAF0C" modified="2014-05-14" version="1">MASILLLANITLLIVIASAQQCNLKTLKTSYPAPVTEDSWDYSIVANELRRPRGILFDSEGALIVIDSGNGIIHFELDDEGGTCLQVRKKTTLLKKDNLNHGIALSKDGRTLYASTSDEVFAWPYDPSKVILRKSSVQTLVSNMTNGGHTSRTLLISQKHPDMLLVSRGSDGNDDAGAEDRDSGRSQIRAFNISSFSSNSDRKPYDYLDGVIIGWGLRNSVGVAEHPETGGIFSVENSADNLHRDGKDIHEDNPGEEMNFHGYLNGSDDQGGNYGYPLCYTLWSTNNFPGLGDLKIGDQFPADRQADGDKATALTDAECKSDYIAPVLAFQAHTAPLDLKFNENGTRAYISFHGSWNRDPPVGYRVSYVDFQNGRPASSSRSTNATTPIIYNKDLSKCPDDCFRPVGLAWDSKGRLWFSSDKTGEVFVLSQESGSGSSGGNGSESGAGNEDDDNDSASLQPGSAAFIITLAALIIGGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK30</accession>
    <name>X0BK30_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK30"/>
    <dbReference type="eggNOG" id="ENOG502SWCQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015773_1_0_1"/>
    <dbReference type="OrthoDB" id="3501032at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711:SF1">
        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="84"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="598" mass="66768" checksum="8181B71B2DFBCDB6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK99</accession>
    <name>X0BK99_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5703 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK99"/>
    <dbReference type="eggNOG" id="ENOG502S39Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009745_0_0_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043757">
        <property type="entry name" value="DUF5703_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18961">
        <property type="entry name" value="DUF5703_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936508" description="DUF5703 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5703" evidence="2">
        <location>
            <begin position="29"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="778" mass="89622" checksum="AEDC439B02EA2375" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BL19</accession>
    <name>X0BL19_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="6">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_12808</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="6"/>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BL19"/>
    <dbReference type="HOGENOM" id="CLU_017779_3_0_1"/>
    <dbReference type="OrthoDB" id="7786253at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000014">
        <property type="entry name" value="D-lactate dehydrogenase (Cytochrome), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF116">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE (CYTOCHROME) (AFU_ORTHOLOGUE AFUA_7G02560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="9">
        <location>
            <begin position="141"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK82840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="568" mass="62220" checksum="D8C80F7731AB90FA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLN1</accession>
    <name>X0BLN1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12589</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLN1"/>
    <dbReference type="eggNOG" id="ENOG502SM08">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040048_1_0_1"/>
    <dbReference type="OrthoDB" id="5088304at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="26586" checksum="F72AA079E67D500F" modified="2014-05-14" version="1">MFFRMSYWTSYLDALIHFCFRHVNRRARILASEPQEYKCVVKHGMEGFRSMLRTRLATHFTFGDMYSALTTETCSLCKNFGDFLFLPTATRCCFACIENAPELRVISLVAFKKLTKVKMKWLTYHIGRVVRTVPGLYSMGEKPARRPGLLLAEVEVARMLSALCLLTPEANEALEVQNEKKNYRFMVSTAYPWYDPNTGQVHSGVSCKGCQIRLETLAVASRDHDGVFSSSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLQ6</accession>
    <name>X0BLQ6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ASCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLQ6"/>
    <dbReference type="eggNOG" id="ENOG502SRGM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103806_2_0_1"/>
    <dbReference type="OrthoDB" id="2149705at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13199" checksum="AE597FA7C473805D" modified="2014-05-14" version="1">MSSPSKAPKRSDMILAMNDPYMQQIIDGVKTYEFRKYNMAGIQRIWFYRTAPHSAITHICPVNEAVTRNPGDQPLPEDGLGNKEYNERDADYEGYDFAYRINAVYEINAEGGQGIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM06</accession>
    <name>X0BM06_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM06"/>
    <dbReference type="eggNOG" id="ENOG502SVRF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168472_0_0_1"/>
    <dbReference type="OrthoDB" id="3489571at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938699" evidence="1">
        <location>
            <begin position="19"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="115" mass="12269" checksum="09A6FCC3F502D17A" modified="2014-05-14" version="1">MQISLFTVALMAISGAHAALHKAAACVSNRVSSPVGGTPFSPSYNWQTTYEVLADATKCACDMYKQRNTGGEMWDTCPDCTFDGTICNSAEGHMGGDEFTYYCEEKCGAQGAEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BND3</accession>
    <name>X0BND3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_12374</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BND3"/>
    <dbReference type="eggNOG" id="KOG3957">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_280613_0_0_1"/>
    <dbReference type="OrthoDB" id="5863171at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050509">
        <property type="entry name" value="CoA-transferase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025496">
        <property type="entry name" value="DUF4387"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48228:SF4">
        <property type="entry name" value="BLR3030 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48228">
        <property type="entry name" value="SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14330">
        <property type="entry name" value="DUF4387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="2">
        <location>
            <begin position="63"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="2">
        <location>
            <begin position="240"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4387" evidence="3">
        <location>
            <begin position="495"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK83356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1127" mass="122303" checksum="987E70B2AB0E4A5C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPN6</accession>
    <name>X0BPN6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_11976</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPN6"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF83">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="491"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="70"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK83816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="552" mass="61981" checksum="0F5D425E987034F8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQW2</accession>
    <name>X0BQW2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979334">
        <property type="protein sequence ID" value="EXK81293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQW2"/>
    <dbReference type="HOGENOM" id="CLU_177156_0_0_1"/>
    <dbReference type="OrthoDB" id="5100176at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="97" mass="10757" checksum="EE4022BA5009B6CB" modified="2014-05-14" version="1">MSSPHYIQVPREGNPTPNIIHQSTTYSEQLNAWLREDHKDIPWHNLDSIVTSSTDTSESGPNTNASHNPATQGSANQASSRPQMPHYVVQQRPAQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRM0</accession>
    <name>X0BRM0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Luciferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658425">
        <property type="protein sequence ID" value="EXK81573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRM0"/>
    <dbReference type="eggNOG" id="ENOG502QSR6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022256_0_0_1"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="entry name" value="Luciferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051260">
        <property type="entry name" value="Diverse_substr_monoxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03860">
        <property type="entry name" value="FMN_nitrolo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011:SF30">
        <property type="entry name" value="XENOBIOTIC COMPOUND MONOOXYGENASE, DSZA FAMILY (AFU_ORTHOLOGUE AFUA_6G01920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="Bacterial luciferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase-like" evidence="2">
        <location>
            <begin position="42"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="484" mass="53635" checksum="6C2027E5CE2C27DD" modified="2014-05-14" version="1">MAPNPATNGNATDNSNNDLKKKIIINAFDMSTIGHLSPGQWKNPVDKSATKRDLQYWIDLAKLLEKGGINALFLADTYGGYDTYEGKLDNCIRRAAQWPMTDPTIPISAMAAVTKNLSFAITASTSFEPPFLLAKRFSSLDHFTRGRIGWNIVTSWKKAAFKAIGLDSPIAHDERYEQADEYLRVLYKLWEGSWADDAISPDPENDSYADPEKIRTIHHHGKFFDLDTRHIVDPSPQRTPFLFQAGTSSAGQTFAATHAEGIFVSSHSPKLLKPKIQAIRKQAAELGRDPQSLKFFATFTPIVGRTDEEAQEKLKELQKYASTIGGLVLVSGWTGIDLSKIPLDQELTSADSLEQHKVQSLLDAFTVTSEHVPKWTPRVIAEKAGIGGLGPVSVGSPQTVADEMERWIEEGDLDGFNVGYVTTPGTFEDLVELLVPELRRRGLYHEIPSEGGHTLRENVYGIGQSGLRDDHTGSKYKYGVFKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSC6</accession>
    <name>X0BSC6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alginate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_13802</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658421">
        <property type="protein sequence ID" value="EXK81823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSC6"/>
    <dbReference type="eggNOG" id="ENOG502QVUY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038125_1_0_1"/>
    <dbReference type="OrthoDB" id="5302720at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008397">
        <property type="entry name" value="Alginate_lyase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05426">
        <property type="entry name" value="Alginate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936641" description="Alginate lyase domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate lyase" evidence="4">
        <location>
            <begin position="62"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK81823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="394" mass="43693" checksum="17077CE1FAE92880" modified="2014-05-14" version="1">MVAKGIVFIVALAVSVTGFVHPGLLHTSRDLERAKNHVLKGDEPWKTDWQLLLNNSRASPTYKPDPQPTIYRGSDGTHAENYPRLYNDAHAAYQLAIRWHIQGDDQYADAAVAILNAWSSTMVAIGGSSDRFLAAGIYGYQLANAAELMRSYSGWSASEQDQMKTFLQDVFFSESYRFLTTHNGQDEYHYYANWDFCNIANIMAIGVFTDNQTMYEYGKNYFLNGDGRGAINNFIYKNYTESGSGKILSQGQEAGRDQGHATLDISLLGVVMQQGYNQGDDLFATLGDAGLHASEYVSKYNVGYDVPYTLYESYEGNQTVISADSRYTHRPGFELVYAHYNDIKHANASWTKLYRDQTNGNSTAGVEGGGGNYGPNSGGFDVLGYGTLLYRLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSM1</accession>
    <name>X0BSM1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_13687</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658419">
        <property type="protein sequence ID" value="EXK81928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSM1"/>
    <dbReference type="HOGENOM" id="CLU_044876_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF4">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK81928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="225" mass="24123" checksum="92EB2AE48EA7ABD6" modified="2014-05-14" version="1">MSTIAVSGGTGGLGRAIVDGLNAAGKSTVVVLSRESTKEKEKELGARMIAVDYNEVASVSAVLEKNNIDTVICTLSAPGPEAELALISAVEKSRVTNRYIPAIWSIPYNSITTTGSKITTRPVSQALGDIPVVLTHTSDVAKFVAAYMERPTWDKEAYIIGNRLTLNELIRLVEEAKGVKFTVTHDSVDDLSAGKVTELPSHPPAYAVFPKESLQGFLAGFDCWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSX6</accession>
    <name>X0BSX6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein pal1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSX6"/>
    <dbReference type="eggNOG" id="ENOG502RB1B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037771_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013226">
        <property type="entry name" value="Pal1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307:SF1">
        <property type="entry name" value="PAL1 CELL MORPHOLOGY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307">
        <property type="entry name" value="PROTEIN PAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08316">
        <property type="entry name" value="Pal1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="46956" checksum="67B5DB33A38C9DB4" modified="2014-05-14" version="1">MKDSSDKQWAKAYILDPLNDIEPNQDTGIGASHNLAAQLRNISLEGSSSNSNSNSNRDRSPERKHRHKPSHSSHRHRQGSYPTPPTSASPTRDSFHSSNPFSDAAAARRQSSAPSVTVSPPDSPPGPSDTRRDPFNSSVNRSASARVPPPRNRPQVSHSRSFSASNCGVSRQRSLIQRYPGDMSHRPLDILRKEARAADRAPHLRRKQMPMADTIDALDTIGGMYHHGGPYDATLASRNRNKMYSPVAAVEDSNREALRATPRENIQDALLKKMPLQGTADIPSGERDISGNTIDYEEGADLMREPDAVGGAYKRWDGIQYHPDDLKGKGEPSYTYEKDLKEQKRFRRGEPVEYELSSNMRGSKRPPFSHNRSFSENPRTTPEFSNGTDIRRNNSTGKHRLSDGIRRRFGSMRRKKVEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BT11</accession>
    <name>X0BT11_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Proline dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_10975</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts proline to delta-1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the proline oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2 5"/>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BT11"/>
    <dbReference type="eggNOG" id="KOG0186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018202_0_1_1"/>
    <dbReference type="OrthoDB" id="5464at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF30">
        <property type="entry name" value="PROLINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proline dehydrogenase" evidence="6">
        <location>
            <begin position="146"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK85036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="482" mass="53333" checksum="1124502D2DD7461D" modified="2014-05-14" version="1">MSSALRRGTAQPLRWATASNAITINTLRPCLTITKTNMVARRHIHSSERRTNTIVEQQQIPDPLPPIAPSKAPLSVLPLIMILRSLATMTVSSSPLLLPPSLHVMGILANTTNPLLNPDKNPLLRYFLKKTFYAQFCAGEKSPEIKKTIDGLKNIGFTGVILNYAKEVVLTKDEGEGLKNGAMETDECIQNEILPWARGTLETVRLAEPGDFVALKFTGAGSIALYQLKDRLPPSPAMYKAIDSICQLAHERGVRLLFDAEQDMLQDGIDDWTLEFTRKYNKGLGEAVIFGTYQAYKKKCPEVLSNHLKLAQIENFALGVKLVRGAYLNSDPRELFHDTKEETDACFDSLAASVLTREWNIDVKGSGEYPAASLVVASHNAESVRRSRAIMEAGRAKSDIAFAQLQGMADEVSCELVEAGQSDKTKILPAYKYLVWGTTGECMKYLLRRAHENKDAVQRTRGSRDALWAELVRRCKSAVGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUD8</accession>
    <name>X0BUD8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13499</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979330">
        <property type="protein sequence ID" value="EXK82114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUD8"/>
    <dbReference type="eggNOG" id="ENOG502SDNF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_604172_0_0_1"/>
    <dbReference type="OrthoDB" id="4842781at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="453" mass="49606" checksum="D031FE51F8488093" modified="2014-05-14" version="1">MPPPPRPSRGRPAFSKQDEDLWKAYAKGLQARFFSNLDTKNEIFYAAPVGLLGIPGGDNITQEITNKGVYEIGDALMQLDAPVFASGGKKYSQRLQEVLGAVRLGRNRDMGAEKRMNDIQTKVRKLNAEYAELSEKAMESYAADEDKGNMPFGQWVSMNYPSFVALSREKQSAAATEASLRAQIAGPGADQLNRQRQRLFNACEPDRDHPGLNMPCALSFGNITNGSSDLSQESGKLPRPAYTIDNSYRDTVGNWTRGSTSENKLNLTFNINDAKSDNWDKFGFVNANANSRFTYFFTATYFQDRQKKEDVITAQDVGSELSVNLSAAEAGVFTVKAGDWDVPNIMEEYRDFQPDAARNIGPAARVDEVILAYKVVLKISLPANVADRVNDLTQKAKSSGGSVSLFGFEVGFGGGSKDEVNISGSSIEIRKDLGYPVLLGVKGKKLPGLQTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVX6</accession>
    <name>X0BVX6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_10105</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVX6"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_4_1"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF147">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK86056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="532" mass="60040" checksum="888A7EB12BEDBD08" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXS7</accession>
    <name>X0BXS7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12051</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXS7"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_27_2_1"/>
    <dbReference type="OrthoDB" id="5086884at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF11">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="35"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="508"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK83698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="518" mass="57433" checksum="8EA7EFDEFA1CF4A5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BY35</accession>
    <name>X0BY35_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Utp8 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BY35"/>
    <dbReference type="eggNOG" id="ENOG502S1FV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013566_0_0_1"/>
    <dbReference type="OrthoDB" id="5330858at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018843">
        <property type="entry name" value="Utp8_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10395">
        <property type="entry name" value="Utp8_b_propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Utp8 beta-propeller" evidence="1">
        <location>
            <begin position="7"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="903" mass="99143" checksum="75F83873BBE2D12A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYK9</accession>
    <name>X0BYK9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF895 domain membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_09335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYK9"/>
    <dbReference type="eggNOG" id="KOG3098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030884_2_0_1"/>
    <dbReference type="OrthoDB" id="196103at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF19">
        <property type="entry name" value="DUF895 DOMAIN MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK86971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="51967" checksum="C4D0DFF0CACAE600" modified="2014-05-14" version="1">MTVVENRHADSEVAPPPKDQLLPVKWYRSTFFNITVLGLCNLSAPGIWVAMNSLGAGGAASPKLINAANALTFCLMVVSCYFSSAMVRYIGIKGALIFGTLGYAPYAAGLYTNNRFGTEWLVLVGAALCGISAGVFWMAEAAIAIAYPEPWNRGKALGYWLTYRLSGQILGGAINLGLNADRNEAGKVSYTVYLIFIALQAVGPFVALLLSKPHQVQRKDGVTVKLEIDKLPSFELKETARLFFTKKFLLVVLFIGQAVFAESVFFTYLALWFSVRSRALGSFLGGIVAVTAGNILGAWLDRTKVSLRFRTRSSFAFLATLQGACWIWATVLVTRFRETRPTYDWVDSGFGHSFAIFLFLTLSFQLNYLFLYFVIHHLANTQDEIIRFSALLRGTESAWQALSYGITSLPLFAEVGGVYFNFALWGLSIFPAWLVLKDFGSHAAPSLESPIQEVDSQNFGSNSGEDSDIKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C146</accession>
    <name>X0C146_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C146"/>
    <dbReference type="HOGENOM" id="CLU_191652_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="86" mass="8773" checksum="25158E7987E8B355" modified="2014-05-14" version="1">MSQGNDPNDSFMTDLRISGMSPVDNSTIRSWSGSPSSVSDKKALASGLWPHTQPETADNTTSVTAASSSSLGANVGFSRAEPAGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1D3</accession>
    <name>X0C1D3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1D3"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_0_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="77"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="316" mass="34526" checksum="4924C756C486C2F2" modified="2014-05-14" version="1">MDTYLDPINRKFADAAAEGPPLYTKTYQEARDILEGIQSYKTASDIKTEEIKVPVNGEDVTTVIFRPASAQGTLNMIFYTHGGGWILGSPTAHGALMEDFARQTGAAVVFPYYTPAPEAQYPVQFEQVYGVLDHFVNNGDKYSLKVDSFGLAGDSVGGHMAIAMTQLAQNRKLPSKIGQIVLLYPVTDTHSKSETYKTFKDGPYLSEKTMDWMIPAFLPNEEDRKLPLTSPLQYAPDEVLAKFPPTTVFLSGADPLIGEGEAFGHRLQQLGVDAAVIKADGQVHDFAMLAPVRVSPTARSVVELASLKLSKAFSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1Q2</accession>
    <name>X0C1Q2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ChrR-like cupin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11192</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1Q2"/>
    <dbReference type="eggNOG" id="ENOG502SNKX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093224_0_0_1"/>
    <dbReference type="OrthoDB" id="4525710at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20302">
        <property type="entry name" value="cupin_DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025979">
        <property type="entry name" value="ChrR-like_cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12973">
        <property type="entry name" value="Cupin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ChrR-like cupin" evidence="2">
        <location>
            <begin position="52"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="189" mass="21456" checksum="D60FD01C8DC0D207" modified="2014-05-14" version="1">MAPAQTQDTSENTQKSSDLLEHPKGESVLTDKDRKALVFTDKHSSPDVYVNSSKDTLWHPWTGTLELKPLRFETRSGSFVIGLRTPVDCWLGKHRHRGTVTAVTLSGNWRYKEYDWAAGPGDYVVENPGTIHTLFMGAGAEVVFTITGSLEFFNDDDSLRETMDIFSFAELYYDHCKEKGVEPNEKLWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2R9</accession>
    <name>X0C2R9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit delta, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">F-ATPase delta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_08445</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2R9"/>
    <dbReference type="eggNOG" id="KOG1758">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084338_0_0_1"/>
    <dbReference type="OrthoDB" id="270171at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.15.10:FF:000003">
        <property type="entry name" value="ATP synthase subunit delta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="entry name" value="F0F1 ATP synthase delta/epsilon subunit, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048938">
        <property type="entry name" value="ATPD_C_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="ATP SYNTHASE DELTA/EPSILON CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822:SF7">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21334">
        <property type="entry name" value="ATPD_C_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="Epsilon subunit of F1F0-ATP synthase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP synthase F1 complex delta/epsilon subunit N-terminal" evidence="14">
        <location>
            <begin position="36"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="F1F0-ATP synthase subunit delta C-terminal" evidence="15">
        <location>
            <begin position="122"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK88670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="165" mass="17733" checksum="F5BEF9013B51A7FB" modified="2014-05-14" version="1">MNSFRVARAALRARPSAIRVPLQRRTYAEAVPDKIKLSLALPHQSIYKSQDVVQVNIPAESGEMGVLANHVPSIEQLKPGLVEVVEESAGSKQFFLSGGFATVQPNSVLSINAVEGYPLEDFSAEAIRAQIAEAQKVANGSGSEQDIAEAKIELEVLETLSAHVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3H9</accession>
    <name>X0C3H9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3H9"/>
    <dbReference type="HOGENOM" id="CLU_152064_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="141" mass="15385" checksum="003FA22D5E946DC3" modified="2014-05-14" version="1">MRTTTAFLTGHGELHSQGALPGKGSWSKAARPAGVQMQPSMTVVSNGKDQSALSGCRSSYWHRRAYRGNGWSLASFHDQARHYVPIDNVTRRTRGLDRAAVTNARLSLPVTHGLKPDSFSAAAAQLRMPSCPLAYKYKTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3K0</accession>
    <name>X0C3K0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658617">
        <property type="protein sequence ID" value="EXK77352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3K0"/>
    <dbReference type="HOGENOM" id="CLU_019833_0_1_1"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="607" mass="68839" checksum="722F00676CEF295D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C431</accession>
    <name>X0C431_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658596">
        <property type="protein sequence ID" value="EXK77522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C431"/>
    <dbReference type="eggNOG" id="ENOG502SY5N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2339123_0_0_1"/>
    <dbReference type="OrthoDB" id="5109581at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="98" mass="10872" checksum="38238ADDA920A2E1" modified="2014-05-14" version="1" fragment="single">MTSRRAPRSTMRTRNTIRVSPASESSRPGASGQDHTPSSMYDSTTVISEKNTLFLPQELKLGGPSNWEQYCPAQKAILRINGLEDAVFGDYPPEEQQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C500</accession>
    <name>X0C500_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_07586</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C500"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="4454541at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF16">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="62"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK89490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="528" mass="58518" checksum="256723009673B8E9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5F7</accession>
    <name>X0C5F7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Nitrate reductase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_10083</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5F7"/>
    <dbReference type="eggNOG" id="ENOG502S5VU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_13_4_1"/>
    <dbReference type="OrthoDB" id="10249365at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02791">
        <property type="entry name" value="MopB_CT_Nitrate-R-NapA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02754">
        <property type="entry name" value="MopB_Nitrate-R-NapA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.90">
        <property type="entry name" value="ADC-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.228.10">
        <property type="entry name" value="Dimethylsulfoxide Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041957">
        <property type="entry name" value="CT_Nitrate-R-NapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050123">
        <property type="entry name" value="Prok_molybdopt-oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF10">
        <property type="entry name" value="NADH-QUINONE OXIDOREDUCTASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105">
        <property type="entry name" value="RESPIRATORY NITRATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53706">
        <property type="entry name" value="Formate dehydrogenase/DMSO reductase, domains 1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="10" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="12">
        <location>
            <begin position="48"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="791"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK86034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="973" mass="108936" checksum="6DBB4A3BE3B9D0E9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5I7</accession>
    <name>X0C5I7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_07516</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5I7"/>
    <dbReference type="eggNOG" id="KOG0253">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_52_4_1"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF4">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="462"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="67"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK89411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="527" mass="56966" checksum="D7F2299A41333D24" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5X5</accession>
    <name>X0C5X5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5X5"/>
    <dbReference type="eggNOG" id="ENOG502QQIF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_797042_0_0_1"/>
    <dbReference type="OrthoDB" id="5097663at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937399" description="WSC domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="34189" checksum="F7ECA218BFC8D70E" modified="2014-05-14" version="1">MVRPVFFASIFAAGIFAQSTADPALTKDGAFQHLGCVAVRPGTFPRQFDLGQAGCTSSCSSNGNIIGFRGNSCVCDRLDLSPGPIAYRVAKVDNALCNQWCDPADRSKGTCGGATIQGWPIYDLYKRNNAQIVYEAFPGATPTPAPTQPIQTGMPIPNPSPNPKPGDVWHECPPNVVNCPYRNKCPNGRCQLKPIVQPCRGCSYNGTGNWTAPTCPPGGCNQGPKPVPVPVPGGNGGSGGSGGNGGNGGNGGTGGTAGNGGNGGNGGNGGSGGSGGSGGSGGSGGSGGNGGNGGNGGNGGNGGGSSGSSGGDGHHGDQPPVIVNSAVTARGESFILALVVISFAFTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5Z9</accession>
    <name>X0C5Z9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09923</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5Z9"/>
    <dbReference type="eggNOG" id="ENOG502S7KB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019703_0_0_1"/>
    <dbReference type="OrthoDB" id="3539644at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="Toastrack_DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4097" evidence="3">
        <location>
            <begin position="316"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK86209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="704" mass="76674" checksum="3171C07A2DC05F2D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6H6</accession>
    <name>X0C6H6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6H6"/>
    <dbReference type="eggNOG" id="KOG1902">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="306690at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990247">
        <property type="term" value="F:N6-methyladenosine-containing RNA reader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057720">
        <property type="entry name" value="RRM_YTH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357:SF3">
        <property type="entry name" value="YTH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25701">
        <property type="entry name" value="RRM_YTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YTH" evidence="2">
        <location>
            <begin position="406"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK90020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="637" mass="69127" checksum="BA6677913747EAA9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C705</accession>
    <name>X0C705_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C705"/>
    <dbReference type="HOGENOM" id="CLU_101435_0_0_1"/>
    <dbReference type="OrthoDB" id="5090804at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="194" mass="20826" checksum="D311B34158FC493D" modified="2014-05-14" version="1">MAPIQVVEHKELKSCSSDFVYGDPKGSYLAAIILAVTLTLMTVISISLCLVASQQKGKLKELQSAQRKASKSSSSTKESTKHVQIVPPTDWQKPGNSPLRHVEPVSPVSSTASSEYEGFSEGAPPSDGYFGSNDQSFTARTERMVAEVRAEQDGSNRVSDKPPQIPRYPFQGSGHKDTAIQDAPSSDSGISVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7T4</accession>
    <name>X0C7T4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LITAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7T4"/>
    <dbReference type="HOGENOM" id="CLU_1147270_0_0_1"/>
    <dbReference type="OrthoDB" id="5599753at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006629">
        <property type="entry name" value="LITAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10601">
        <property type="entry name" value="zf-LITAF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00714">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51837">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="LITAF" evidence="3">
        <location>
            <begin position="150"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="259" mass="28403" checksum="4AD66CC694509E86" modified="2014-05-14" version="1">MRVVSLLIFQVHSSNLNLNFHSLNFFTASSTPVEMSTVSPETTNADIISPPKYTANAESPRDEKIAIEQPKVDDENLPEVVTEQTSPAQMSPPPASEYRPVSTVSPAPESTMNWDGTQSPPILQHPALAQQQYAGHQSMVIPAQQTPQVPPGETVTPLHLLADQADTMDCPFCQRRAETKVKKSASSMTHIYATALFFTTLFGVIFPYACHCAPNISHFCKNCGRKVAFKERGGQMEALGTPDHLREVSKYPAAPPKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAQ0</accession>
    <name>X0CAQ0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAQ0"/>
    <dbReference type="HOGENOM" id="CLU_2440932_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="90" mass="10608" checksum="CCEDCE8B1B9656C0" modified="2014-05-14" version="1">MSRRSRYNVVYGYAVPVLHRSYYAVNRYSKTKNSELETIQRRSFPFSSKESEVEVEVELIKRCYNIANVSLIVRSCMTGWQHRDGLEGMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAS2</accession>
    <name>X0CAS2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="2">6.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_06677</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (L-Gln route): step 1/1.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="2"/>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAS2"/>
    <dbReference type="OrthoDB" id="409189at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000031">
        <property type="entry name" value="Asparagine synthase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000050">
        <property type="entry name" value="Asparagine synthetase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050795">
        <property type="entry name" value="Asn_Synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772:SF2">
        <property type="entry name" value="ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="6 10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="14">
        <location>
            <begin position="2"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="11">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="375"/>
            <end position="376"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="13">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK91201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="586" mass="66520" checksum="85BD428C701DE57F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CC01</accession>
    <name>X0CC01_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CC01"/>
    <dbReference type="HOGENOM" id="CLU_096545_0_0_1"/>
    <dbReference type="OrthoDB" id="5597238at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936304" evidence="2">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="197" mass="19211" checksum="AE6E1E446ABED6FC" modified="2014-05-14" version="1">MRFTSIFVAGAFATMAAAQSKTASVSPAQQSQLDCLDACDAGDVKCQSYCITVPSPDEKNINATTECVAACPKGKGSASDTEKYSVCLQDCIANNYWKTIDGTPQETGAAGSKDKASSAAESAASKATGTASDEGSTATASASESDATATGASETASGSASGTASGSAAQSSETGNAATALVGGVSLLGLVAAVFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD89</accession>
    <name>X0CD89_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Metal ion transporter C27B12.12c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_06063</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD89"/>
    <dbReference type="eggNOG" id="ENOG502QPTQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007127_6_1_1"/>
    <dbReference type="OrthoDB" id="29879at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010961">
        <property type="term" value="P:intracellular magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12829">
        <property type="entry name" value="Alr1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000006">
        <property type="entry name" value="CorA family metal ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044089">
        <property type="entry name" value="Alr1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535">
        <property type="entry name" value="MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535:SF55">
        <property type="entry name" value="MAGNESIUM TRANSPORTER ALR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="596"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="71"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="239"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK92136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="623" mass="70214" checksum="844377D7CDC807B5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CED0</accession>
    <name>X0CED0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF803 domain membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_05663</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CED0"/>
    <dbReference type="eggNOG" id="KOG2922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012349_5_1_1"/>
    <dbReference type="OrthoDB" id="6428174at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF92">
        <property type="entry name" value="SPICHTHYIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="408"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="469"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="496"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="522"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="605"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK92561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="622" mass="68361" checksum="A444A0019C06A6EF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEM2</accession>
    <name>X0CEM2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Neurofibromin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEM2"/>
    <dbReference type="HOGENOM" id="CLU_2133617_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="113" mass="12881" checksum="48B1AAB2567A1F41" modified="2014-05-14" version="1">MLYSCVLWPRFSLTTYARLLPTFHPLSARFATPYQTQSCHGSPMPSTQLWEPSSSYDSFAQLSLLLKSRASCRQHHLKKCGAVYFLLPRSFRTSPITCCLEQKSHTCFPLTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFG6</accession>
    <name>X0CFG6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14218</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979333">
        <property type="protein sequence ID" value="EXK81357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFG6"/>
    <dbReference type="HOGENOM" id="CLU_052361_0_1_1"/>
    <dbReference type="OrthoDB" id="3360610at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004493">
        <property type="term" value="F:methylmalonyl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046491">
        <property type="term" value="P:L-methylmalonyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07257">
        <property type="entry name" value="THT_oxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000034">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000039">
        <property type="entry name" value="Trihydroxytoluene oxygenase (AFU_orthologue AFUA_8G02470)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051785">
        <property type="entry name" value="MMCE/EMCE_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048:SF3">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="164"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="320" mass="36758" checksum="F31E688354221030" modified="2014-05-14" version="1">MTSSPTRRIRLVRLAHVYYSHRDIAKAHQFLEDFGFEQTANLGNKTYYRGTGPEPFVYCAVEGPEDSFGGAAFVVESFDDLTYAANTLPNATPVTKMQSEPGGGYRVTFYDPVDNFPFHLVYGQKEVDPLPKSLPERVINFPTNKNRAGNTFQRFEKGPAPVHKMGHFGMVVTNFEKAFQFYTSRFNFKPSDLVYNESGHDITTFLHLDRGKELVDHHCFFFFEGPKSHVHHSSYETHDFDTQLLGHHWLRERGYENCWGVGRHVMGSQIFDYWFDTSGFIMEHYVDGDLVDDTYPTNRQKASPDNLHVWGPDVPPTFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHE1</accession>
    <name>X0CHE1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PUL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHE1"/>
    <dbReference type="eggNOG" id="KOG1216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_266878_0_0_1"/>
    <dbReference type="OrthoDB" id="5119629at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052824">
        <property type="entry name" value="m6A_RNA_Methylation_Regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13585">
        <property type="entry name" value="CHASCON, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13585:SF19">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="520"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="577"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="601"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="631"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="666"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="827"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="970"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1141"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="841"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1145"/>
            <end position="1173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1209" mass="138425" checksum="55E38EC1225C757B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CI75</accession>
    <name>X0CI75_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CI75"/>
    <dbReference type="eggNOG" id="ENOG502RMTI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3368498_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="35" mass="3794" checksum="4CCCE4F525655126" modified="2014-05-14" version="1">MAATDSAGGGREGLNKRATGRLLEGEKTPHWKWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJ17</accession>
    <name>X0CJ17_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phospholipase D1</fullName>
            <ecNumber evidence="3">3.1.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Choline phosphatase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Phosphatidylcholine-hydrolyzing phospholipase D1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_06693</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14445"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phospholipase D family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="3"/>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1329">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="14911at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01254">
        <property type="entry name" value="PH_PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09138">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09141">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.870.10:FF:000011">
        <property type="entry name" value="Phospholipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF76">
        <property type="entry name" value="PHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00614">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="12">
        <location>
            <begin position="914"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="12">
        <location>
            <begin position="1218"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="518"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1321"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1427"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1584"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1636"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="164"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="541"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1361"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1380"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1396"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1427"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1584"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1636"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1657"/>
            <end position="1672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1676"/>
            <end position="1687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1734"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1757"/>
            <end position="1769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00074658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00079280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK91253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1825" mass="205075" checksum="AF7757EAFEC4F91B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJ72</accession>
    <name>X0CJ72_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_04537</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJ72"/>
    <dbReference type="eggNOG" id="ENOG502SNQY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027371_0_0_1"/>
    <dbReference type="OrthoDB" id="5229455at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF7">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK94485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="436" mass="48975" checksum="1A5FE391F04EEF6F" modified="2014-05-14" version="1">MQSSESAASAQLGSLADSDTSTVVTKRRPIPRKGHTKSRAGCSSCKRRRVKCDLTTPECGACERLGLECEYLNKTRHGSQNSAVVISQPLRTDPVMFDYNDLNFFRHFLFEAYPPLPIDGFTVWQMASQRSHSYDFLLHSMLGLGASHLSLLTPHGYEKAALKHRVLAISALNKHLAKPGLTNQDAEAAFGAMLNLTFQSAYMNDGLIDFLTMVRGCWLVGTQPYVDLDHTIFKTFGRVSYLERIKALIQDGHETNHYLDKVIAEGFCQSVQKLGPLCHSVAELKYLAHMQRIATLASTNPAESYHELTFLYDGLGNLSSNDFASFIDPTNHASQLVILHMLVLEFVMSRKSVEGDMRSALGKKGYHCRKAMSKVWVQQILRKLPVEYYEYGEWPLRFINSLNYSFDDEDQVWKPFFLSNGRTVVPAGETLSLAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJC1</accession>
    <name>X0CJC1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Btz domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_06509</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CASC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK90934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJC1"/>
    <dbReference type="HOGENOM" id="CLU_018142_0_0_1"/>
    <dbReference type="OrthoDB" id="5413466at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018545">
        <property type="entry name" value="Btz_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044796">
        <property type="entry name" value="MLN51_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46837">
        <property type="entry name" value="PROTEIN MLN51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46837:SF5">
        <property type="entry name" value="PROTEIN MLN51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09405">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01044">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Btz" evidence="14">
        <location>
            <begin position="135"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="202"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="545"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="598"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="598"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="634"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK90934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="722" mass="78558" checksum="510F11DD7D203F4A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJR6</accession>
    <name>X0CJR6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_06281</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJR6"/>
    <dbReference type="eggNOG" id="KOG1485">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013430_2_2_1"/>
    <dbReference type="OrthoDB" id="78296at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1350:FF:000003">
        <property type="entry name" value="Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000005">
        <property type="entry name" value="Putative Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF12">
        <property type="entry name" value="CATION DIFFUSION FACILITATOR 1 (AFU_ORTHOLOGUE AFUA_1G14440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="8">
        <location>
            <begin position="170"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="9">
        <location>
            <begin position="378"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="65"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK91533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="454" mass="50634" checksum="E3C0B0CB9C67C0A9" modified="2014-05-14" version="1">MTPDNSNHVAHHPQAIHLQSLERARSSSRHSTTRNGSSTAFEPATADENETIARNVSHMTDVESQLTATGRRQPSCLDHDPYGLSRGYKTESDLEQIKANTSRKRDSLPGRKTVSGEVGPKTKARKLQGFYKNQNAAIDRMLKSVEEHRDEARDQHGEDQVKFRIAVWGSFAANVALSGVQLYAAISSKSLSLFTTMADSIFDPLSNLTLILSARAIRHVDSRRFPAGKARLETVGNIVFCFLMIAVSLIIIAFACQELSRGVQEKEFKIAAVISVCCAFATKFVLFLYCWALKDKYSQINILWQDHRNDLFINGFGILTSCGGAKLKWWIDPMGAIILSVLISCIWLHTAFGEFLLIVGVTASVETQQLITYVCVTHDDAVVGIDTVRVYHSGPRLIAEVDIVMDPTQTLQESHDIAEALQTKLEDLPDIERAYVHIDYETTHKPEHAFKKDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKK7</accession>
    <name>X0CKK7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial genome maintenance protein Mgr2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_04685</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGR2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKK7"/>
    <dbReference type="eggNOG" id="KOG4096">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142435_3_0_1"/>
    <dbReference type="OrthoDB" id="5409308at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018450">
        <property type="entry name" value="Romo1/Mgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525:SF1">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10247">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01378">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK94691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="11769" checksum="A5573010E18EF08D" modified="2014-05-14" version="1">MPPVAPINAGQHGPSNVDKLKMGAMMGGTVGVIMGFVFGTVNIFRYGAGPNGIMRTLGQYMLGSGATFGFFMSIGSVIRSDADPKLHEMYMRAQRRPIMLMANPAWRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPA6</accession>
    <name>X0CPA6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_03366</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPA6"/>
    <dbReference type="eggNOG" id="ENOG502QPVP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2341546at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000003">
        <property type="entry name" value="C6 transcription factor (Leu3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF21">
        <property type="entry name" value="REGULATORY PROTEIN LEU3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="133"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="636"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="641"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="663"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK96265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="748" mass="83366" checksum="3B387BCA3143B89F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ63</accession>
    <name>X0CQ63_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_03592</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ63"/>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF6">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="54"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK96590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="569" mass="62693" checksum="998C05BAB2E811E5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS54</accession>
    <name>X0CS54_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_10700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS54"/>
    <dbReference type="eggNOG" id="KOG2615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_54_6_1"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF39">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="83"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="292"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="298"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="324"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK85342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="582" mass="62650" checksum="C86EC3B5AD6A3066" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSD5</accession>
    <name>X0CSD5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Isotrichodermin C-15 hydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_02394</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSD5"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902181">
        <property type="term" value="P:verruculogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000063">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF237">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ATNE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="9 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK97061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="59807" checksum="40ED50D59DA6E451" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTS8</accession>
    <name>X0CTS8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_04693</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTS8"/>
    <dbReference type="HOGENOM" id="CLU_005043_1_0_1"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06595">
        <property type="entry name" value="GH31_u1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF89">
        <property type="entry name" value="ALPHA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="5">
        <location>
            <begin position="193"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="6">
        <location>
            <begin position="507"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK94698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="804" mass="92016" checksum="956B4FF053813E1D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVA6</accession>
    <name>X0CVA6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA polymerase eta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_01108</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVA6"/>
    <dbReference type="eggNOG" id="KOG2095">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012348_7_1_1"/>
    <dbReference type="OrthoDB" id="5723at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009314">
        <property type="term" value="P:response to radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.100:FF:000009">
        <property type="entry name" value="DNA polymerase eta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.60:FF:000008">
        <property type="entry name" value="DNA polymerase eta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000014">
        <property type="entry name" value="Polymerase (DNA directed), eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052230">
        <property type="entry name" value="DNA_polymerase_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041298">
        <property type="entry name" value="UBZ3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873:SF1">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21704">
        <property type="entry name" value="POLH-Rev1_HhH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18439">
        <property type="entry name" value="zf_UBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036603">
        <property type="entry name" value="DPol_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51907">
        <property type="entry name" value="ZF_UBZ3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UmuC" evidence="13">
        <location>
            <begin position="46"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="UBZ3-type" evidence="14">
        <location>
            <begin position="604"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="496"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="641"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="653"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK98096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="683" mass="76186" checksum="66966696A7CB6DEE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVB0</accession>
    <name>X0CVB0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03626</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVB0"/>
    <dbReference type="HOGENOM" id="CLU_1081970_0_0_1"/>
    <dbReference type="OrthoDB" id="25131at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00413">
        <property type="entry name" value="Glyco_hydrolase_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121:SF5">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937983" description="GH16 domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="27"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK94799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="298" mass="32985" checksum="2C576B0D6F0A3BF9" modified="2014-05-14" version="1">MIFSLTHLLVTARLVSGACECGYSIKNPQGDSPIVFTDRLETKFSQLHKISEGHDWVAQNFTVSAADGRGNFSKAFLPTNVNTRGTKSGDDSGLELRYFNDTQEIDIEFLSQEFDHDNGIYPINLVVQSKKSLEAGYDASRTGSFKRVRLDFDPTDAFHEYRFDYLPGQVLFYADGKLLARMKGGDMPSSGGHLILQHWSNGNPLWSGGPPKEDATVTVSFVKAYFNSSNSERQSQLVQQCHKSSEETSGCAVYDSDNDEIDNAAASTRRVAQGNFVCVLIVGLIMPFLQLSHVFLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVB7</accession>
    <name>X0CVB7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MET18/MMS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVB7"/>
    <dbReference type="eggNOG" id="KOG1967">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="342900at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039920">
        <property type="entry name" value="MMS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024687">
        <property type="entry name" value="MMS19_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029240">
        <property type="entry name" value="MMS19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891">
        <property type="entry name" value="DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891:SF0">
        <property type="entry name" value="MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12460">
        <property type="entry name" value="MMS19_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14500">
        <property type="entry name" value="MMS19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="MMS19 N-terminal" evidence="6">
        <location>
            <begin position="65"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="MMS19 C-terminal" evidence="5">
        <location>
            <begin position="760"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1164" mass="128138" checksum="413C18F0AE30BE76" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVN6</accession>
    <name>X0CVN6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Quinate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_09816</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVN6"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="508119at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF34">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0672">Quinate metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="12">
        <location>
            <begin position="29"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK86547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="534" mass="58523" checksum="55F0C025F6E3C85B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVT4</accession>
    <name>X0CVT4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03986</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVT4"/>
    <dbReference type="eggNOG" id="ENOG502T9FE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_792359_0_0_1"/>
    <dbReference type="OrthoDB" id="3692311at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="363" mass="40313" checksum="01D612FB2287F21A" modified="2014-05-14" version="1">MSDYDPVKDLGLTCPYGGILYICADDPDRFIGCCTINPCGARKGLCPDQNLRSASFNATLQHEFLPQACINDNVDVSWYTCAGNALPFLGCCAVDPCLRGVCPQGDLRAAKLSDKAKNAQEFLDGSPEYMPRPTSSVLDPGLGISSTSLCASPTTAMTTMISSFINSFATETTIATITSARTTLPSEAPDAPPAGPKEHGSNRRLTWLLMLLFAAVFLVLYLAHHFWGHPCCPECGDKPSKVKLEQRHEQEHRHDQQQQEYEHNPNMPPYPDTDETRTSDDFRNMRERSSRNSSRTVHEHPQNMQGQQHENDSAIKDGTSRDNKENGILDLHRDSNQQDLYAYVLGTVPNRKPLPRTNTQPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVX7</accession>
    <name>X0CVX7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_04027</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVX7"/>
    <dbReference type="OrthoDB" id="7396853at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF1">
        <property type="entry name" value="AROMATIC RING-OPENING DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G00640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="6">
        <location>
            <begin position="8"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="291" mass="32753" checksum="7FC1A810A26C4EC2" modified="2014-05-14" version="1">MKANLSPVHFFSHGSTMMLGEDSESADYWKKAGDQALANNIKGVIMMGAHWDAEGDRMQVAMNPKPGKSPVAYVHPSKYVDYELNPDLETGERCISLLKDAGFNASGNTEFDWIHDTYLILVRMFPNGCPPTTLISMNARFDPHYHMRVGETLRPLRKENYLIIGSGGAVHNLYRNIWAPILYYSDNFAQEKPPEAWALEFRQAVEDVIKNNSGPRLRRAMARLMKHPLYRDAHATDDHFMSALFVAGAIGDEEDEGVYGELKAETWELTNMCNSQFTFGSWPRTLATAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWI6</accession>
    <name>X0CWI6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rad21/Rec8-like protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_01410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWI6"/>
    <dbReference type="eggNOG" id="KOG1213">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025342_0_0_1"/>
    <dbReference type="OrthoDB" id="5427633at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030892">
        <property type="term" value="C:mitotic cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21790">
        <property type="entry name" value="Rad21_Rec8_M_ScRec8p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21789">
        <property type="entry name" value="Rad21_Rec8_M_SpRec8p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="entry name" value="Structural maintenance of chromosome 1. Chain E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039781">
        <property type="entry name" value="Rad21/Rec8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006909">
        <property type="entry name" value="Rad21/Rec8_C_eu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006910">
        <property type="entry name" value="Rad21_Rec8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585:SF70">
        <property type="entry name" value="RAD21_REC8 N TERMINAL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G02900)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585">
        <property type="entry name" value="SCC1 / RAD21 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04824">
        <property type="entry name" value="Rad21_Rec8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04825">
        <property type="entry name" value="Rad21_Rec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Rad21/Rec8-like protein C-terminal eukaryotic" evidence="4">
        <location>
            <begin position="629"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="414"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="483"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="305"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK98531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="685" mass="74631" checksum="80568865AC33FADB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXJ6</accession>
    <name>X0CXJ6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXJ6"/>
    <dbReference type="HOGENOM" id="CLU_125557_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="185" mass="20531" checksum="A87743013E75F3AE" modified="2014-05-14" version="1">MNQTANTYATYKPRAMVADILGYFRRSLMSKNTITRHRIVESPLSSTIPISESYTTRPTIAMIQCRAHQRLYLTSLCTFNLFTGVTSFVGSYRPMSGMSVRDVSPHSTRATTSRCGTLGLCVRLDQGPPFPGTAKMQRRGAPVIPGQGCFIQHKYSKRLIGTTSPARSSASTVVRGRTLRVKTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY83</accession>
    <name>X0CY83_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA repair protein RAD57</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_03088</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY83"/>
    <dbReference type="eggNOG" id="KOG1564">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013059_1_1_1"/>
    <dbReference type="OrthoDB" id="1861185at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061982">
        <property type="term" value="P:meiosis I cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19491">
        <property type="entry name" value="XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047348">
        <property type="entry name" value="XRCC3-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF66">
        <property type="entry name" value="RE19845P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="8">
        <location>
            <begin position="79"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="265"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="297"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK95809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="439" mass="47236" checksum="379F8B55D6AD548D" modified="2014-05-14" version="1">MTDLLQILPSFPLRPFAALIPTIEQQALTTTDLLTLHPADIAKQTRLPILDLKRLIAAIQASLSDDLSPQQPLLQPAEEPKVISTLDEGLDAALGGGVPVGVITEITGESGAGKTQALLSLCLAVQLPPPHGLGREALYISTEAALATSRLAQMLNSNPILQQYDDPETRPSLDAIHSAVTPDLETQDHILDFQVPVLLSRHKIGLIILDSVAANYRAEFERQGSHGSNMAARSAELVRLGALLRDLARRHNLAVVVANQVADRFASSSTPRHAPPRSSGVAYESPLASRSMPPPSSTNLPGTPSSSLPFALQDPDGPPPPPALMLDHQQRWFTGWGDDPHASYSLKTPSLGLVWSTQIACRIALFKRPVYGRIRQAAPVTAEDDSDLAAPTLRGWRRWMKVVFAPHAPQTGQGLDGAVEFEVTMGGLKSTKIQKAKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZM6</accession>
    <name>X0CZM6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZM6"/>
    <dbReference type="eggNOG" id="ENOG502RQ3U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_943486_0_0_1"/>
    <dbReference type="OrthoDB" id="5096204at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="266" mass="29204" checksum="CCF82114DF12E5E7" modified="2014-05-14" version="1">MPKSAPPRQGNFRSNPYGTWISPGFAGSQNTYYPSPSSRFDDPPFGMQQRAWGPPSLGSPERPYDVIIPPPELNRSQRVAPVPPPPPYSTETTEQRSKHGFLGGPPTSAAAENPGAQDFKPAQQFWSPQTQLFERQKQPLKQVDSMVLQAVTRNSRWGKEAPDLRVISNSKGGGTQCNVYSKVPSVAKTISFNVDDEEALLKAYRHVKAMNPSAPVGGIMFSIGAKGDRSQVDNISWNSFAGRSGLGRSFSMNLNGDNIQVFRPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZW3</accession>
    <name>X0CZW3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZW3"/>
    <dbReference type="eggNOG" id="ENOG502T0H9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041042_0_0_1"/>
    <dbReference type="OrthoDB" id="4366798at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="401" mass="45723" checksum="55204963417DBFC1" modified="2014-05-14" version="1">MDDPGWSWPAWKFGMKRDDLFHTLHEKYNTFTFNLQDPEAFHHDVYEISRDADTVDDFHRLLDERKQQRIHELHESLESLAVEIIANPKLMDSEHWQYALQLFRTKSFDSIVRYFASYLPEQYLDHNDRDHDAISIASLSSFSETNSVKTESTTASSVDDASSFFDDEPILTKGPLSIHTDIRPSSVVQAPPSPPHSEAAHGDESSVSSPTSMESHEYSTPPSRSMSFSGSETAAAISDLTRSLVHDEDETSQFDDGDFAVASDSDCAESQSSLDVMDDGEQSNDKYEDDLEEEDDFPTTQFPEDASDGCDFYDDTPNFDDTPTPRQESIAPCYIEYKSVAAWRIPSPRRSPSPSPRSHHPYRREGSSLKDIRRSPEESMSKIQKPMHEQRKRPTFRKRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D079</accession>
    <name>X0D079_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NPP1 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Necrosis inducing protein (NPP1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D079"/>
    <dbReference type="SMR" id="X0D079"/>
    <dbReference type="eggNOG" id="ENOG502S1MP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062263_1_0_1"/>
    <dbReference type="OrthoDB" id="89086at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936736" description="NPP1 domain protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK96963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="24704" checksum="43FF5EC9B9ECE314" modified="2014-05-14" version="1">MVLITQLLSGLALASGILASPIERRAVINHDAVVGFPQTVPSNTAGSLYLKYKPYLKVFNGCVPFPAVDSNGNTGGGLATSGSSNGGCSSSPGQVYVRGGTYNGRYGIMYSWYMPKDSPSPGLGHRHDWENAVIWLSGESTSATVVGMAVSQHGGYDKRTSGTFSGNSPLVGYTAIWPTNHQMIFTNDQGGQQPLIAWESLTAAARTALTNTDFGSANVPFKDGSFESNLDKAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0U7</accession>
    <name>X0D0U7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0U7"/>
    <dbReference type="eggNOG" id="ENOG502RJF0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_792358_0_0_1"/>
    <dbReference type="OrthoDB" id="5090201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="413" mass="47273" checksum="C02DE612BDC8109F" modified="2014-05-14" version="1">MAVPSITVSSPKTTSESPMTRAATSPIEWDHYYSGARFSENRDIAMNGPQGGEYDSVYDVEEEGLDENFVYGRLSPVPAPRQDTRTLSDMNGYLPGYRFVGNRDIEMDKVDLEYESSFHEFTFEHPFRHAEDFEGFSGCWCEDDYEADVSESCFEESSEEYTEFDGSWEEDNVSNAYEDAPEYSVCESPAGFKGNDSGYYVSTEYEESIDDLSGNDREHNDMTVEEAVYTVPRRLANMEDTNWGLRKRKFDEYEEGQIEEDEFYEDESDDVQIEEPYPEVEDDYGTLSDVDMCMEHVLECGVCSDLDFNSTDAPQDHENSPEAYTFQDGDVEFEEFPQRLPTILEVDEPTSPFPPGYADYVPEDTYVDGCFGLEDEFYPDEAGLPVEEEGKDYNGPYFNDAQLDLAEVKYTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0X4</accession>
    <name>X0D0X4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P-type Ca(2+) transporter</fullName>
            <ecNumber evidence="2">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_08627</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="2"/>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0X4"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000040">
        <property type="entry name" value="Calcium-transporting ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000028">
        <property type="entry name" value="Calcium-transporting P-type ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="929"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="963"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1000"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1032"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="15">
        <location>
            <begin position="61"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK88337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1070" mass="116150" checksum="124DC88A6F8310F9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2P0</accession>
    <name>X0D2P0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcription factor MST12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_00918</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Transcription factor that may function downstream of PMK1 to regulate genes involved in infectious hyphae growth. Is not essential for vegetative growth, conidiation or appressorium formation. May be involved in the regulation of the expression of the cell surface sensor MSB2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the STE12 transcription factor family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2P0"/>
    <dbReference type="SMR" id="X0D2P0"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025505_0_0_1"/>
    <dbReference type="OrthoDB" id="1095242at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990526">
        <property type="term" value="C:Ste12p-Dig1p-Dig2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990527">
        <property type="term" value="C:Tec1p-Ste12p-Dig1p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000243">
        <property type="entry name" value="Probable transcription factor steA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000390">
        <property type="entry name" value="Transcription factor stea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003120">
        <property type="entry name" value="Ste12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052127">
        <property type="entry name" value="STE12_transcription_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47427">
        <property type="entry name" value="PROTEIN STE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47427:SF1">
        <property type="entry name" value="PROTEIN STE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02200">
        <property type="entry name" value="STE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00424">
        <property type="entry name" value="STE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="556"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="586"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="213"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="402"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="602"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="630"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00054208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00074197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXL01041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="696" mass="76591" checksum="5AD0F4BB9D521CDE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2Z0</accession>
    <name>X0D2Z0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vesicular-fusion protein sec17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02674</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SNAP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2Z0"/>
    <dbReference type="eggNOG" id="KOG1586">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046329_1_0_1"/>
    <dbReference type="OrthoDB" id="9984275at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15832">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000049">
        <property type="entry name" value="Alpha-soluble NSF attachment protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF8">
        <property type="entry name" value="ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00448">
        <property type="entry name" value="NSFATTACHMNT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK97494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="33028" checksum="9987DD85E5E62AB8" modified="2014-05-14" version="1">MAQDPRALLQKAQKQLQSAGGGFSFFGGREEKYQEAADLFTQAANAFKMQQQNLEAGKAFEQAAQVQTDKLKEPDDAANTLVDAFKAYRKDDPQAAARCLNIAVDRYCAKGNFRRAASHKENLGELYEVELGDAKSAIECYELAATWYEGDNAAALANKLWLKVADVAAIEGDYYKAIEKYERVAEQSINNNLMKYSVKDYLLKAGICHLASGDLVAAQRALEKYRDMDPSFGAQREHQLLTDLCEAIEAKSQEQFTDRLYQFDQISKLDKWKTTILVRVKNQIEEEEDEEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3K4</accession>
    <name>X0D3K4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxin 26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3K4"/>
    <dbReference type="eggNOG" id="ENOG502S0P1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046457_0_0_1"/>
    <dbReference type="OrthoDB" id="3981028at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22265">
        <property type="entry name" value="UDM1_RNF168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXL01007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="461" mass="51359" checksum="2E11CF020F2DFE38" modified="2014-05-14" version="1">MTFNNHAAYSPTTMSSSTGPSGLPNSLLSTSISSLASSTSSRHPSQISKTYRQASTLFLTRRLPEALTTLLPLITPPEHVDDGEPAPVARASRTTRIKVWSLYLTILNGIVELEPEEGKDAFGNQEWRALCTKVREGEIWDEVVTNGYHGVEGDVDSDVVINLATILLAHARDQKLNQHKLEAYLAASNTPNLDVAGRLAESTSSPMSNRYRSPAKGASGANTPRDLNARVKILELYTLHVLLRNNEWDYAREFISVSSVLDEERREAFLQALQSLHDEQQEQERLENEERQRQENELKREIEEAKRLRAENEEKERKRIEEERLKREGSEVDYGIDDTASHTGSTRPRKARAPSSSSSRQSRPRGTNQAGPKANGKAVSQAPTLTSRASMVIAQLRTIIEHLGSSLNSNPMFLVKFLAFVMGLILMLSNANIRERVKRILAVFWSKVKGTAGMGVKVSYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7I5</accession>
    <name>X0D7I5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7I5"/>
    <dbReference type="HOGENOM" id="CLU_007383_10_5_1"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051604">
        <property type="entry name" value="Ergot_Alk_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162:SF1">
        <property type="entry name" value="PRESTALK A DIFFERENTIATION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="9"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="304" mass="33439" checksum="609F6BC4FCDCF6DE" modified="2014-05-14" version="1">MHVAIAPASNKTSSAAISSLLSQNREIQVRGLYRDLKKVPNEFSSADNFEAVQGDVGDGNTLDFSGSDAVLMVLPPAYDGRDIIEHAQRISNNVKTAIERAGSVRRLVLLSSVGAEFSEGVGELKTNHISEEVLKTTDIPEIIIIRCSYFMENWTMSVETLKGPNPFFFSTITPLDFKIAMVAIKDIGEAMATQLTRDWTPPTKPYVMELHGPEPYSPLDAQKAFSQALGKDVEIKAVEKEDLSEFYGKIFAPQIVNEWVEMSTCFLPGGIAEKDLSKPSDVDVIHGKTTLTEALREATAELRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0D841</accession>
    <name>X0D841_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D841"/>
    <dbReference type="eggNOG" id="ENOG502SN25">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006594_0_0_1"/>
    <dbReference type="OrthoDB" id="3870679at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="962"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="413"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="964"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1013"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1013" mass="113400" checksum="1D38A4186EC37FE2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0D925</accession>
    <name>X0D925_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_00385</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D925"/>
    <dbReference type="eggNOG" id="KOG2732">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3763at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07387">
        <property type="entry name" value="MPP_PolD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.430:FF:000002">
        <property type="entry name" value="DNA polymerase delta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.50:FF:000006">
        <property type="entry name" value="DNA polymerase delta subunit 2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040663">
        <property type="entry name" value="DNA_pol_D_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041863">
        <property type="entry name" value="PolD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18018">
        <property type="entry name" value="DNA_pol_D_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA polymerase delta subunit OB-fold" evidence="12">
        <location>
            <begin position="47"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="11">
        <location>
            <begin position="226"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="190"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXL00069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="503" mass="55753" checksum="A173A2A36F7DE4FA" modified="2014-05-14" version="1">MVTLEDVEGSLLRKPSETSHQVPSRSASVYKPLQSFVLDKQRSYQQQYGDMYFLRLTKIKPAVDKVAAEAWTGTKIGEEEAQRVERVLDVRQGELCWVTGTVYMEMPLKPNILEDVSKDRWISAPILTPKYFSKDDQVMLEDESGRIRLVGDVLKTVNLVTGCIIGVMGTENANGELEVIDIKFPDLPPQPDRWSLSKPNSEKAKTKDEDEDMADASEAKKGNSKIAIVSGLSFSGTDASHALELELLSEYLLGEAMTPLSQIDVSHISRLVIAGNSISTTDRKPPAADEALPEKKAQKKYGYDASAYNPLPSQLFDAFIAELLPSIPITMLPGAQDPANASYPQQPVHPAMFPSARAYARDPAAPATQPGWFDTVTNPWEAELEGWRFLGTGGQNVDDVFKYVGSDDRLGMMEAMCRWRCCAPTAPDTLWSYPFQDDDPFVMQTCPHLYFVGNQPHFTTKVIHGPEGQSVRLVTVPSFAETKELVLIDTETLEVERVKISAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0DAY4</accession>
    <name>X0DAY4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DAY4"/>
    <dbReference type="eggNOG" id="ENOG502SZWN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052692_0_0_1"/>
    <dbReference type="OrthoDB" id="3641178at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="398" mass="43954" checksum="B549EED5207465FF" modified="2014-05-14" version="1">MAALLPQPIHTATSSPWPSRTSSLSMSPRMETCRASVTETNSPEWLPQALSETLHVLPYTSTEWAKVISDVKREYLNRRYRPCATRCSEILDNLKDFSIVEPAYLIYLHFYAANSQEMLARALHQAAPARTTLLNQARDHYQRASTLINAADSTVGPALLRRPSGTTTTLPSLHSADSSVSSHVSSTWTSSHGISPASSISSIQSVPTSKRKKKRVTFSDVPVELLERPDSPTLGLGSFLGPARSISPELSAGDSSAVLAPLRSLTQAPRSILTPRSAQNEVSPSTDAELDPFRHARSVHRYSALLTSLQRQVFRHLNFIETELGQQHTTPPYEDTPPSPTTVNMVTSVSATPNADKTRSPELQARIERLRAKGWERKRFDARRYAELRESASADMND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBS4</accession>
    <name>X0DBS4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_00891</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBS4"/>
    <dbReference type="eggNOG" id="ENOG502S0WX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009353_1_0_1"/>
    <dbReference type="OrthoDB" id="3921198at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF15">
        <property type="entry name" value="PRNA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="527"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXL00999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="762" mass="85495" checksum="825A2D82ADB6DF68" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBX2</accession>
    <name>X0DBX2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="4">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_00703</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="4"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBX2"/>
    <dbReference type="eggNOG" id="ENOG502QWBM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031468_2_1_1"/>
    <dbReference type="OrthoDB" id="3609at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF30">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="5">
        <location>
            <begin position="6"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="6">
        <location>
            <begin position="197"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXL00615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="330" mass="36094" checksum="922911E8F37E102F" modified="2014-05-14" version="1">MDKARILLVGCGGIGCIAALNLEFGGRAEVTAVLRSSYQIVKERGFTIDSVDHGQIRGFRPTEILPSIPDVSKSGISPFDYVVCATKNIPVISTPVADIIRPAVTPGYTTILLLQNGLNIQVPVQEAFPDNVILSGISMCGSSEPKSGTIEHNLHDELRIGPFEDFGNAAERAKDLVARFNAGGRCTCHYDDNVTFSRWKKLLYNAVYNPVGALTRLDTGDMQLCPGLVDEVIRPGMKEIQAAAAAYGQELTDEMIEATIVTEPIDAHVSPSMLIDVRKEQYIEVENLLGEPLRAAQARQVPTPILQNHYSLASSYQWKLHSKKDISEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0DQC3</accession>
    <name>X0DQC3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mannose-P-dolichol utilization defect 1 protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_03519</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the MPDU1 (TC 2.A.43.3) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DQC3"/>
    <dbReference type="eggNOG" id="KOG3211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053568_0_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000006">
        <property type="entry name" value="mannose-P-dolichol utilization defect 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016817">
        <property type="entry name" value="MannP-dilichol_defect-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226:SF2">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023381">
        <property type="entry name" value="MannP-dilichol_defect-1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="256"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR023381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK96507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="288" mass="30460" checksum="464771DEA81F5FDA" modified="2014-05-14" version="1">MEALKSAITPITHNLPAPIRDLGVSIIGETCYKSLLLDVNIEDADCIKFAVSKALGIGIIAASSIVKVPQILKLLNSKSAEGVSFLSYLLETTSYIISLAYNFRNGFPFSTYGETALIVGQNVIISVLVLNYSGRASLAAVFVAVLAGTVATLFAENVVDAQTLSYLQAGAGVLSVASKLPQILTIFQQGGTGQLSAFAVFNYLAGSLSRIFTTLQEVDDKLILYGFVSGFVLNAILALQMIFYWNAPSEKAKGKQPAAPIAAKPATLTPSSSTTATPKKSPTTRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0DSI6</accession>
    <name>X0DSI6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DSI6"/>
    <dbReference type="HOGENOM" id="CLU_019987_0_0_1"/>
    <dbReference type="OrthoDB" id="3941134at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="844"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="543"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="724"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="844"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="918" mass="99178" checksum="B47438044FF49D1C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0DUH3</accession>
    <name>X0DUH3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Gluconate 5-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DUH3"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF115">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK97882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="300" mass="31700" checksum="4DDD8ABB8912C847" modified="2014-05-14" version="1">MSDPTAREDLTKRQLPSMTLANGIESLPSAAQARTASTSDDSSTRFQVSGVAVVTGGLGTIALTVVRALLQHGVTGLMLLDLDVTSESAISKMDDLRKDFPKRKIEAASVDVTDEGAVGQVMASTVEKLGGLDYLLCFAGIVNCTHSLELSPKVFRKLLDVNTTGSFICAQAAAKEMVKANTGGRIVFIASISAHRVNYPQPQVAYNTSKGALLMLKSSLAAEWARYGITVNSISPGYMDTILNEGEGLADARRSWAERNPSGRMGMPEELSGMVVLLCSKAGSYINGSDMVVDGGGIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DXT0</accession>
    <name>X0DXT0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DXT0"/>
    <dbReference type="HOGENOM" id="CLU_3359706_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="36" mass="4276" checksum="153BE0B0185379CF" modified="2014-05-14" version="1">MQYRYGMAARLWHNGVNGDLHEHSVSIFNVHRSDNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2G8</accession>
    <name>X0B2G8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Alternative oxidase</fullName>
            <ecNumber evidence="17">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">FOQG_18947</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16 17">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="16 17">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the alternative oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="17"/>
    <dbReference type="EMBL" id="KI979544">
        <property type="protein sequence ID" value="EXK76305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2G8"/>
    <dbReference type="HOGENOM" id="CLU_041974_3_2_1"/>
    <dbReference type="OrthoDB" id="16906at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098803">
        <property type="term" value="C:respiratory chain complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009916">
        <property type="term" value="F:alternative oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010230">
        <property type="term" value="P:alternative respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01053">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.140:FF:000002">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.140">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002680">
        <property type="entry name" value="AOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038659">
        <property type="entry name" value="AOX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803:SF3">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01786">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005229">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 16 17" id="KW-0408">Iron</keyword>
    <keyword evidence="14 17 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 17" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 17 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="303"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR005229-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EXK76305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="341" mass="39160" checksum="F0BE1E171E04D60F" modified="2014-05-14" version="1">MGNAAAFGFVRSAPLRFFLLRSSAVPRVTGAAAQLRQIQPFSSTPAARLRDFFPAKDTTRIKTTRPAWPPHSYTYEEMTSVIPGHREPRGTADWAAWKVVRFARYCMDKATGMNREQQVDKNNPTTSIVAQKPLTEAQWLTRFIFLESIAGVPGMVGGMLRHLSSLRRMKRDNGWIETLLEESYNERMHLLTFMKMCEPGWFMKVMIIGAQGVFFNGLFVCYLFSPKIVHRFVGYLEEEAVHTYTRCIKEIEEGHLPKWSDPSFRIPDIAIQYWNIPVERQTMKDLILYIRADEAVHRGVNHTLGNLNQNEDPNPFVSEFKDREAPKPALQPSGYERTDVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2R5</accession>
    <name>X0B2R5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979514">
        <property type="protein sequence ID" value="EXK76415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2R5"/>
    <dbReference type="HOGENOM" id="CLU_2158539_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="111" mass="12965" checksum="B9BF655E8441331C" modified="2014-05-14" version="1">MIRPIVEVPREINHRVSLRIESFEGRGKFLDWGRRHGSPRCPGNMAHRRRRILNPRAFIDTSCLRRGALKMMSRVIRRRLATLRSFDGMRHPLSGLSSPSNQYLKTLNEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0B377</accession>
    <name>X0B377_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658701">
        <property type="protein sequence ID" value="EXK76590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B377"/>
    <dbReference type="HOGENOM" id="CLU_162806_0_0_1"/>
    <dbReference type="OrthoDB" id="2559882at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="100" mass="10509" checksum="48FA8DC946ACAEBD" modified="2014-05-14" version="1">MSGINQNEHGQGASHASAPSKVPEGVQRQAPQGLEESLLDSVHPTGSEPGQSTNKFHAKSGGEASIVPQKLQEKLPESVERAVPNAIHDTGDTSGLHRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7T7</accession>
    <name>X0B7T7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YesU protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979375">
        <property type="protein sequence ID" value="EXK77831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7T7"/>
    <dbReference type="eggNOG" id="ENOG502SIFZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1238456_0_0_1"/>
    <dbReference type="OrthoDB" id="4264714at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015305">
        <property type="entry name" value="DUF1961"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09224">
        <property type="entry name" value="DUF1961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935564" description="YesU protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="25915" checksum="454117985F653021" modified="2014-05-14" version="1">MRSLLLYPLLAASAMAEKLLYRNTFNSTEAIADWVAEGPVKATVSNNTLELAAPGDFVYWVPEVFPERIRITWEFSPIEEPGLAIIFFGAAAAKDGGSIFDKDLKPRNGSYPQYHSSDIRTLHASYFRRRWPEERAFHLANLRKSPGFHLVAQGADPLPNVEDTQGAYYKVEVIHDKRDVKFSINGLELFSWEDVDRSTGPVIRGGRIGFRQMNPLVARYRNLEVWKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9Q7</accession>
    <name>X0B9Q7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658495">
        <property type="protein sequence ID" value="EXK78885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9Q7"/>
    <dbReference type="HOGENOM" id="CLU_202045_0_0_1"/>
    <dbReference type="OrthoDB" id="3920481at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="56" mass="6243" checksum="7D44A1609CC6312B" modified="2014-05-14" version="1">MDSIQLPIASVEVLRCMRCARSVEATSTDDIGAMGMVRIAHNLYYCERCAKMVGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9V8</accession>
    <name>X0B9V8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16417</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658491">
        <property type="protein sequence ID" value="EXK78940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9V8"/>
    <dbReference type="eggNOG" id="ENOG502QS99">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028622_1_0_1"/>
    <dbReference type="OrthoDB" id="202545at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044:SF2">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="47478" checksum="C611CCD3EE174170" modified="2014-05-14" version="1">MTSKIRSTLCTLGSYIAGTLLTFAMKVFVAAGDTQVVDAILQAINRSLEAMTQSLSGAALIWKAIFTNDINKPSLNFILNHLPELGQFLYDLIRPGTVLGRFPSTDGPPESLDAEFPGIDNPYNELDLWLPENRNAVVCQAQRVALTIVAILKLGRGKMPNGLDDVQLNVSLRSDFDANANPPSPTYISALHGGPPSPPNEKWLFINGIANEFFWFQRSCDKIRDTFNREVTGVYNRSDGILWDFIECCSERRDGEPNTLIKGTQSSKAAQKALEQELRAALWPAAAKVPDKVVMIAHSQGCLILRLALQTLVTETPKGSPQRRIIKERLRIFTFGNPSIDWKVIDGTEQPLSKYVYTTEHFANKTDFVAMLGVVMHRDDKGSGYDPNMVFYSKTGKAHLFGAHYSLGVDAYHGGENSQLLKAVNGTEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAS3</accession>
    <name>X0BAS3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979708">
        <property type="protein sequence ID" value="EXK75923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAS3"/>
    <dbReference type="HOGENOM" id="CLU_2776044_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK75923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="69" mass="7403" checksum="4658619EC5E42F5A" modified="2014-05-14" version="1">MSWTTLAETGTPNKDHLTRGEGSRQPGGAQVDQGIGVSSFIAALSSGFAIFMLQLLLFLLLRNKLGRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAV0</accession>
    <name>X0BAV0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658475">
        <property type="protein sequence ID" value="EXK79270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAV0"/>
    <dbReference type="HOGENOM" id="CLU_000288_6_10_1"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="183"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="681" mass="76503" checksum="C832E6E5CC20BDCD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB60</accession>
    <name>X0BB60_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PD-(D/E)XK nuclease-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658487">
        <property type="protein sequence ID" value="EXK79016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB60"/>
    <dbReference type="HOGENOM" id="CLU_027219_0_3_1"/>
    <dbReference type="OrthoDB" id="5094484at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046797">
        <property type="entry name" value="PDDEXK_12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20516">
        <property type="entry name" value="PDDEXK_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PD-(D/E)XK nuclease-like" evidence="2">
        <location>
            <begin position="156"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="418" mass="46784" checksum="2A68D2AF0827A2F6" modified="2014-05-14" version="1">MNHPIDEWIRQVSRANGAGADDVIQQQDLNILRKRVYLSPDNITPRAPILPLRNVTSPVPSISPSKRSVTSSQASSSRASSSRQKLSDLQIEDEGIQIRHLESPLDPQLPEPIKDALVVLIYLQRGQHVFSPTLDKNAVAGITEAYLLDEATVFSPSQNSGSPLSPSEADHVLTHAKTCFKENEDESVWNVEVHQRLLEKVLRRSGSNRLLDFRICTTAGIIREYLPSTTSDRKIDFCFCIDTAKDATYASKAIALRQSLPGSSLNHSNKVALQSRLLPVSIETKRASIDFEGAILQISVWQAAHWKMLRYVLAQPWPTSRSGLSQQDYVNKALAELGALPGILIQGHQWYYVASSPDLKNDEGNNTARTSLWLQKPIGSTDNALIIHQIAAFLEFPRRWSLETYWPWFKGHFFDTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBV3</accession>
    <name>X0BBV3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sterigmatocystin biosynthesis monooxygenase stcW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_15780</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658466">
        <property type="protein sequence ID" value="EXK79645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBV3"/>
    <dbReference type="HOGENOM" id="CLU_006937_6_1_1"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF12">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK79645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="561" mass="63642" checksum="82D5B7F8E0D6EBF2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC32</accession>
    <name>X0BC32_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658463">
        <property type="protein sequence ID" value="EXK79695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC32"/>
    <dbReference type="OrthoDB" id="10469074at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="337" mass="38747" checksum="2C4DE84FD6975584" modified="2014-05-14" version="1">MSQEKESTCLSLLRCIRRLTLDFELDLDLKEICSYTRSLSTEIGILQGWKNTIKTIESDKECTDLLKNLRGYLKLLFGNEKGNVRRKDVIDKLKGLSFDITVLVGLSCPDTRKIDLSVCEAIVNLYPDFKRYFTLISIFGRKNVRGKILSETITYAEKIHDGRIGFDELRDFKEAGPQTSRKHGRNDSEQTEIEFAERPLKMRPKPSHGHGGSISENDQRLTQSDYVEEEDDVEEEHNDKTNNNDGGNNKQSNKDPTGDVYELDKLSLIDLVFEPKLVTSIMLTIRPPNEDPTKASFLTIWAERELGDELAKKHVLEEVWLLPRRCSKPRQEKEGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC44</accession>
    <name>X0BC44_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979612">
        <property type="protein sequence ID" value="EXK76079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC44"/>
    <dbReference type="HOGENOM" id="CLU_3406470_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="30" mass="3283" checksum="98E728FD3357F850" modified="2014-05-14" version="1">MFSGLYGSSCFSARKKTPTALSPFTTVRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCN2</accession>
    <name>X0BCN2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase family 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979480">
        <property type="protein sequence ID" value="EXK76583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCN2"/>
    <dbReference type="HOGENOM" id="CLU_034303_0_0_1"/>
    <dbReference type="OrthoDB" id="549336at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="46141" checksum="A5C2101586CA1FC5" modified="2014-05-14" version="1">MFASRPASRYLTVAACTLLLLAFYQFSLLTTSGSPFASKKVKVSVIESKGCHDEVSASYLSALGQLSECNSNVFLAAQRFGIDSIYKLIPGADNRKLVTDNEFRPQYFESEIAAEPDIVLSVTSEYDLIDAKLKPAFAHLLHNTSSILFATVHHGNEWTDDRRFQAVKPWIKAKRLRFITLSDHVTNYMTGIVKHWVTKMEAHDVPISTFPPVFTIPTAPMKNEATLRFAMQGDLVVDRRPNRDYEGTFKRFAKLNSTDQAIELHVVGNGGLLKVPDEAKDRIKFHRGLPYPEFYEVLHSTTAMLPAFASHEYVESKASSTIAASLIVGSPLIADDVLLNAYRFLRRDDVYYRERGEDEIDVVERIAKLPKQDRLAKAEGLREKNELLTKQGGDLFRQWISESRKCLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDJ1</accession>
    <name>X0BDJ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_15564</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658455">
        <property type="protein sequence ID" value="EXK79886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDJ1"/>
    <dbReference type="HOGENOM" id="CLU_026673_20_2_1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="9"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK79886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="331" mass="35838" checksum="12A443B066DA9D46" modified="2014-05-14" version="1">MSLITVYRGTRSGRVQEGTVPSPGPPKTHQVTVRITHSGLCGTDEHYKCQDMVLGHEGVGIVESIGSSVVTLKVGDRVGWGYCHGSCLNCEYCDQGQELYCEQRQFYGFDEFDQGSFATYATWNEHFLFRIPESIPSAEAAPLMCAGAAVYSALRSAGVQWHHRVGVLGLGGLGHLAVQYAAKMGCHVTAYSHSSGKEEAARNLGASDFQVLGDTSTSSRAVDCLLLTGSQQSDWSQALSLVRRGGVISAVTVDSSELRCSYGEVLMNAMRIQGSLPAAPNVQREMLNFSALHGIKPIIEAFPFTEDGINEAMEKLRQGRMRHRGVLAMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE21</accession>
    <name>X0BE21_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979458">
        <property type="protein sequence ID" value="EXK76704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE21"/>
    <dbReference type="HOGENOM" id="CLU_2922737_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="61" mass="6725" checksum="07235753B8B33D56" modified="2014-05-14" version="1">MAGQPKSRWTSLALLASATSSMLLRRGKMRLQTSMNSFSNLAEKSSFLPCSPWLLACQSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEL2</accession>
    <name>X0BEL2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979430">
        <property type="protein sequence ID" value="EXK76929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEL2"/>
    <dbReference type="HOGENOM" id="CLU_2687940_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="74" mass="8196" checksum="EFB8D166C99EFAA8" modified="2014-05-14" version="1">MTTSRTSRVMVPSALCETTMGGFSQHCNRHYNVSTLRSHKYNTSLQKVALKSTYNSQAGNGLSGYRGKETHAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFK8</accession>
    <name>X0BFK8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable glucan endo-1,3-beta-glucosidase eglC</fullName>
            <ecNumber evidence="5">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Endo-1,3-beta-glucanase eglC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Laminarinase eglC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">FOQG_14551</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Lipid-anchor</topology>
            <topology evidence="3">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 22">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="5"/>
    <dbReference type="EMBL" id="JH658432">
        <property type="protein sequence ID" value="EXK80940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFK8"/>
    <dbReference type="SMR" id="X0BFK8"/>
    <dbReference type="eggNOG" id="ENOG502QQE6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028820_2_1_1"/>
    <dbReference type="OrthoDB" id="1293114at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF13">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE EGLC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0134">Cell wall</keyword>
    <keyword evidence="17" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12 24" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0964">Secreted</keyword>
    <keyword evidence="11 23" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="23">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936289" description="Probable glucan endo-1,3-beta-glucosidase eglC" evidence="23">
        <location>
            <begin position="24"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00025152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00032134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00032906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EXK80940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="302" mass="33552" checksum="79679C9D613EEB6E" modified="2014-05-14" version="1">MKLFGSIGAVAAALMLLPGQALAGQYKGFSMGANRADGLCKYTADWKKDFQTIKSWNKGFNAVRLYSADDCNTLVKAVPAAKQTGMKILVGVWATDDAHFGRDKAALLKVIKQYGTDWIAAISVGSEDLYRKDISPDKLAQQIYDVRGMVRQFNKNLKVGHTDTWTAWVDGRNDVVTKACDIAITNGFPYWQGVPIKDALRLKTFQNSYWNVQKHVKAVNSKAAVWVGETGWPTKGPNYQKAAATTASLQSYYNNVGCWLWQQKDASGFWFTAFDAPLATPEVEKYFGIANKDRKLKFSLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFX8</accession>
    <name>X0BFX8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sterigmatocystin biosynthesis monooxygenase stcW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_14498</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979336">
        <property type="protein sequence ID" value="EXK81070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFX8"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_6_1_1"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK81070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="67909" checksum="F9992A5932D21D4D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIZ4</accession>
    <name>X0BIZ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fucose-specific lectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16904</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658520">
        <property type="protein sequence ID" value="EXK78439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIZ4"/>
    <dbReference type="HOGENOM" id="CLU_028617_0_0_1"/>
    <dbReference type="OrthoDB" id="4696326at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.70">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89372">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936953" description="Fucose-specific lectin" evidence="3">
        <location>
            <begin position="25"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="54379" checksum="8CDC45E91971902C" modified="2014-05-14" version="1">MMTSMRVLLLVFVFLLAEPVVGLAAWWTRSSEDIITPHFAYQDPKSGEILHSSCNSIGSAAFSTLKPKVFPISDNIPFKSQPKFSTALAVAGWWDDDLNTPMASVFYQAVDNSIVKALFQCDNKTGYYTFDTNGKTVVSEIAGAPSVYKETGLAAVKLESPGEYQLHYHDEQRLVNLLSSTNETDWHYNGPVSLMSLDNTALASVHTGSTNISVIWPHRGDYGITVANFKEDNEDKWSLESFPSPFPRSGLTNNSDARDFASRAGEPPPLDPPSSWESWRVNLSIAANLDSQLSVFYIGEDAQLHEYLQQTNGSWIEQASPGANKWPKADDQFGRSAAASPPNFDDMWIYYESGNDVVELYRDRRGLWKDAQITRLTTARNVDPDSGSNGNDGSSGTSSSSEAGETENLTRGAKIGIGIGASVGVLVIAIATWFLLRKRRQTTATTETHEPPELQDTGKVELSDTAKFELSDTAKFELSDTARYELPGDSSFQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJG1</accession>
    <name>X0BJG1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658415">
        <property type="protein sequence ID" value="EXK82280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000570_3_0_1"/>
    <dbReference type="OrthoDB" id="1262810at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052957">
        <property type="entry name" value="Auxin_embryo_med"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32387:SF0">
        <property type="entry name" value="PROTEIN NO VEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32387">
        <property type="entry name" value="WU:FJ29H11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1336" mass="152583" checksum="E974E1144AB14203" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJU2</accession>
    <name>X0BJU2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658508">
        <property type="protein sequence ID" value="EXK78699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJU2"/>
    <dbReference type="HOGENOM" id="CLU_1454485_0_0_1"/>
    <dbReference type="OrthoDB" id="4990927at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="213" mass="24575" checksum="B6BE3E067DA47BCD" modified="2014-05-14" version="1">MNDSQPLLVVVVHKAQHRDSSRSLYIRTIIQHAKAEMSNPIFLPATESMQNLCQQQREKEVQSERGPLREYKATITDTKILCKFENEHAHNIRRQALHKGKIISKARNYGPRELDKGTIASPERTITVFIPLATQTADTQRVPKVLYQPDKDKAEFRQPLPWDIGNHIQIPGNSRIVVEEGPVGFDMVQYDWEPAEGQESKDEQRNRAETIWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK68</accession>
    <name>X0BK68_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_13129</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK68"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="59"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK82560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="479" mass="53669" checksum="2FF17C5568865C50" modified="2014-05-14" version="1">MSDFEFAGDDSADDASSVASDESCRFETVQISDTEEPELYRKGGFHPVHIGDHLDERRYRIVHKLGHGGFSVVWLAYDSLESIWVALKIVAASDSSMMEEKAVMWHNIISKMNDERFVTYKRFFHIKGPNGRHLCLVLPPCGPSCNTLSQYLQSRIHPWLARRVAFQATKAIADLHSQGLCHGDFTPSNIVFRIRNLDHLDDKGIYQLFGEPQRDGLRTISGEPTGAEAPRYIVGNLDFTSAEDLIRDDICLIDCDQAFLIPAPPRKPLGTPPGFLAPEVAVGKSASLASDVWALGCSILQIRSGSSPFSIPNVDSPANLLGWVSEYIGRMPTSWGEPLFDDDGLPTTDTTNGESLGEILENTRSLKQWISDIWDQPDNLEELQSTSTAPDRVKDENKPYLECYSNKFWKPAAIRIDDIYLGAYSDKVDKIIESLQKISTHEADLLYDLTSKIFVYEPAQRVSARDILAHPWFHMDDMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BL25</accession>
    <name>X0BL25_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Antigenic thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979345">
        <property type="protein sequence ID" value="EXK79598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979345">
        <property type="protein sequence ID" value="EXK79599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BL25"/>
    <dbReference type="eggNOG" id="ENOG502SP7Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144311_0_0_1"/>
    <dbReference type="OrthoDB" id="3682664at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006771">
        <property type="entry name" value="CetA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04681">
        <property type="entry name" value="Bys1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738190" description="Antigenic thaumatin-like protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="16492" checksum="5A8AB43D3EE83CB9" modified="2014-05-14" version="1">MKFAAFTALAAVFGSAAAANKANVINDCTNTIYVQSFPYGGGAPGPLTTVKPGQRFSEDLRASGSTIKIATTRTLTKPLFFGYSSESQPNNVYYELSTEFGNPFADKHNILSPGEGCEKFDCQPNDAKCYSTPSMKKVYGCPSPVNLYAKVCAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BL58</accession>
    <name>X0BL58_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_15816</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979344">
        <property type="protein sequence ID" value="EXK79633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BL58"/>
    <dbReference type="eggNOG" id="KOG0067">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_2_1"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12168">
        <property type="entry name" value="Mand_dh_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF281">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="3">
        <location>
            <begin position="82"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="129"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK79633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="346" mass="38198" checksum="5C765C2AB147912C" modified="2014-05-14" version="1">MPSAEKPIVLHIGDPIKYNHDLYKKLESKFTIIRPSAEERQRGAFLEALRQKKWGDFQAVMRPFWITGGEMGRWDNGLIPLLPKSMKVYASAGAGYDWADVDIMAENRILYCNGAAASTEAVSDMALYHIISVFRNMQWSNMAARGSEEEFRDAHAHTQLTAFNPRGHTLGIIGLGNIGYQIALKTHKALGMRIAYYDPFPKPPEQEAAIEATNYPKLEDMLAIADCIVIAAPGAGGNKILGREEISKMKRGSRLVNVARGSLVDEEALADAMDSGHLFAVGLDVFEDEPRPNPRLQKMRNATLTCHTAGGALDTSIGFERLAMENVMAVLEGKDAITPVNKHLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLF6</accession>
    <name>X0BLF6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLF6"/>
    <dbReference type="OrthoDB" id="6079484at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34706">
        <property type="entry name" value="SLR1338 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34706:SF1">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="549"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="579" mass="64839" checksum="90E185662E6CE950" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLU8</accession>
    <name>X0BLU8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_15924</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658470">
        <property type="protein sequence ID" value="EXK79454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLU8"/>
    <dbReference type="HOGENOM" id="CLU_011226_14_2_1"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF3">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR URE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="62"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK79454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="24550" checksum="EF110C4BF881238F" modified="2014-05-14" version="1">MCYIHYWFRPLLNSEAFKSINPNAKTPAIEDPNTGIKLFEAGAIILYLLDTYDTSGSIHSLSGPQKYLELAWMQFQATEQHMYYSQQAWFLYKHPEHVKSALERYEWTIKRTIGMLEEHLNKTGKTYLTGDEITFADLCFVVTNELIPQLLPGYDPSKDFPHYSKWNSALVNRPSYQKIAADRAALGQPLGQVDQKHIDDHIWRNDPDHKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMP0</accession>
    <name>X0BMP0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658463">
        <property type="protein sequence ID" value="EXK79714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMP0"/>
    <dbReference type="HOGENOM" id="CLU_028279_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="339" mass="38218" checksum="1420ADCF642BA0BC" modified="2014-05-14" version="1">MTFSLDEIVNTVVKHSLSNRRPRGEKKALAVAEKAPNDSTDSIILKHGKDVWSAYYAATHATHLQQGFGGKADLTSKLRFLEKQDVDTRETFANRLAQKMNEPDTNEPDTNEPTRSPAKRPRTTDHNITDSIQPRTTTNGTDTLSDIVRAYDPQQIPDHNLPIGDVYLGASLEEAKKLFNKDFWDTIKRVPSKENPHELTADVSIIFHQDFNLHMFGCQVEIGITNVMLSHTVLKLYDASIRCVGGFVSALLPGGCLIEPGDGGFTLRRCRRDLSVIFEGDLYQGVCSSPIYMKEGRQARDYTEAVSIRIQRREEHGATIIVHVAEFWATRMMQNLYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNE3</accession>
    <name>X0BNE3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_15417</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979342">
        <property type="protein sequence ID" value="EXK79994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNE3"/>
    <dbReference type="HOGENOM" id="CLU_006926_1_2_1"/>
    <dbReference type="OrthoDB" id="3266505at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF6">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK79994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="698" mass="76439" checksum="BE8259BFDB94BD7B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP08</accession>
    <name>X0BP08_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658450">
        <property type="protein sequence ID" value="EXK80169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP08"/>
    <dbReference type="HOGENOM" id="CLU_3392394_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="4003" checksum="BD0582A2B026E851" modified="2014-05-14" version="1">MFLSYHGANKEHPEQLRQMWHPNFRIHWLGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPY8</accession>
    <name>X0BPY8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_14505</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK80983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPY8"/>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="OrthoDB" id="5212574at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF130">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="333"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK80983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="46613" checksum="6AEC6C93CA17A6B3" modified="2014-05-14" version="1">MDLESSESDDCSPFARFAESVSLRVSDETSQEEEEPGWCRSTLIVLSSHFVVMNTSGFTNCFGALQSYFIGEFGEPSSAVSWIGSMQIFLYFFIGAFSGRLTDAGYFRVTFFTGSLAHVVGIFTASFGSELWIMFVTLGLGVGLGNGLMSCPMLAVMSQYFTKRRGMAVGITMCGSCTGGLIYSSILRQLISSLGFPWTMRVIALIQFVTLAFANICLRPRTSAKSISGWVDWTAFRDVRFNHYAIATFMSLLGLYISIFFIVDFSRTSISPSLSYRNGLSLLMIFNGVNAIGRFGSGLAADKFGVLGVFVPVLVATSLTLFTWISVRTVPSMYVWTVFCGIFCGGIQSLFPAGLGYLTAGTEQPGTRMGMVFGLGSIASLIGSPIGGALVGAMDGNYLGAQVFGGATMALSALFLEATRRADKRMVRCSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQA3</accession>
    <name>X0BQA3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQA3"/>
    <dbReference type="HOGENOM" id="CLU_2740096_0_0_1"/>
    <dbReference type="OrthoDB" id="5576763at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="71" mass="7852" checksum="42AB5275E4BDE284" modified="2014-05-14" version="1">MQSYNWNNSITNHDYSKQPFSQVFFGNPTSKTKGASGGKITLIYEAGECVKKLNLKATQTGKGYQIQAGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQJ0</accession>
    <name>X0BQJ0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658437">
        <property type="protein sequence ID" value="EXK80729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQJ0"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057148_3_0_1"/>
    <dbReference type="OrthoDB" id="10017101at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053173">
        <property type="entry name" value="SAM-binding_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45128">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45128:SF1">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RV2258C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="76"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="299" mass="33384" checksum="6876A31D6E5D51B1" modified="2014-05-14" version="1">MFPNYHVSQTARAVQRIMHQRAGVFPSGPYGKPMANAVRSMASKPSYTSNQMYNFDECFAHRNIGYNSPHIASYVKENTRILDVGCSTGAITLSLAKHNPSGYVLGIDHEPGAIALAKQHAKEEGITNVEFRVTNAEDMDDIQDESFDIAHAHQVLLHVTYPITVLKEMRRVAKTGGIVATRDNCHVFRHPEHPLLEQHVNKFIARSLARGAHPVGSHLNHEWVNEAGFPWECIEMGAGSWDWSSPENKRNWTSGVLAGGLGPIEGIDRAALEKEVEEWVRNPRTRIIALDSWVIGHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR70</accession>
    <name>X0BR70_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Hydroxyquinol 1,2-dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_11177</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR70"/>
    <dbReference type="eggNOG" id="ENOG502QWDJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046727_2_0_1"/>
    <dbReference type="OrthoDB" id="5238185at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018576">
        <property type="term" value="F:catechol 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009712">
        <property type="term" value="P:catechol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03461">
        <property type="entry name" value="1_2-HQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039390">
        <property type="entry name" value="1_2-HQD/HQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF7">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="8">
        <location>
            <begin position="32"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="7">
        <location>
            <begin position="111"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK84655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="36756" checksum="752AA23D226107E5" modified="2014-05-14" version="1">MLIMAAPVNLKDLTIDNITENVHAINSQCSNLRLKYILERVVTHLHDLARETRLTTDEWMTAIQFLTQVGQICTDVRQEFILLSDVLGLSLLVDSIDHPKPKGSTEGTVLGPFHTHEAEHVKEGSLISQDTDGEPLLVLCTLKDVNGSPIPGAKIDVWETDSKGFYDVQHADRTGPDGRAVLTSDDNGDFWFKAIVPVPYPIPHDGPVGKLLKVLGRHCYRPSHMHFMFKKDGYDPLITALYLKDDPYETTDAVFGVKDSLIVNIKKVEDEEMAKKYGVKIGSALMTYDFVLVSDEAAAKLRREKAEEAMAKLGRNFRFIDDLPVPDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRA3</accession>
    <name>X0BRA3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK81014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRA3"/>
    <dbReference type="HOGENOM" id="CLU_3125148_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="50" mass="5792" checksum="5E33BC9D6515E70E" modified="2014-05-14" version="1">MIKMVKVTRKQQYWSHIKLISTQVAVRSSSTTGADPKSRAERHSARIHWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS39</accession>
    <name>X0BS39_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-ornithine N(5)-monooxygenase [NAD(P)H]</fullName>
            <ecNumber evidence="4">1.14.13.196</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_14260</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-ornithine + NADH + O2 = N(5)-hydroxy-L-ornithine + NAD(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41512"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-ornithine + NADPH + O2 = N(5)-hydroxy-L-ornithine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41508"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.196" evidence="4"/>
    <dbReference type="EMBL" id="KI979334">
        <property type="protein sequence ID" value="EXK81299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS39"/>
    <dbReference type="eggNOG" id="ENOG502SJUF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_307548_0_0_1"/>
    <dbReference type="OrthoDB" id="76038at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025700">
        <property type="entry name" value="Lys/Orn_oxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38663">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38663:SF1">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13434">
        <property type="entry name" value="Lys_Orn_oxgnase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK81299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1002" mass="114123" checksum="904117836712DF17" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSC3</accession>
    <name>X0BSC3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-asparaginase II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979332">
        <property type="protein sequence ID" value="EXK81384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSC3"/>
    <dbReference type="eggNOG" id="ENOG502S95P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062004_0_0_1"/>
    <dbReference type="OrthoDB" id="2588474at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010349">
        <property type="entry name" value="Asparaginase_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42110">
        <property type="entry name" value="L-ASPARAGINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42110:SF1">
        <property type="entry name" value="L-ASPARAGINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06089">
        <property type="entry name" value="Asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="39383" checksum="AC6A5C4E17E3ADF0" modified="2014-05-14" version="1">MTRTTLLDRDCVVTDRGGIIENTHGVHIAVTDTEGNILFSAGNPSRVTHSRSAAKPAQAVAVIETGAVDKFGFDETDLALMCASHSSEDFHIARAKNMLSRIKAEEDDLRCGGHPAVSEEVNREWIKTGFEPTGICNNCSGKHVAMMAGAEALGADVKDYHLPDHPMQLEVKRVVDDLAHDPKQVEWGVDGCNLPAPAYPLFYLARKYATFADAADAVEASSPTSQRTQNFARIFNAMTKHPEQVGGTGRFCTVLMQSYQGQLFGKVGADASYGIGVRESEDTRRLGAKGGLGIAAKIEDGNLEILYAVVPEILEQLGIGTLEQRGRLDGFHHLQRRNTMNEVTGRVRFNFKVRPFGDRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTG0</accession>
    <name>X0BTG0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_13434</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTG0"/>
    <dbReference type="HOGENOM" id="CLU_2757820_0_0_1"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF99">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK82193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="70" mass="8069" checksum="BAEBAEED5FEBFA70" modified="2014-05-14" version="1">MVDEAHERTTNTDMLLALLKKLIQQRKHLKLVIMSATINLEKFCQYFGTTNVFETKCCPHKASEDTTNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTV5</accession>
    <name>X0BTV5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NADP-dependent mannitol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10393</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTV5"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="31768" checksum="8143B0BF27657517" modified="2014-05-14" version="1">MSPSALDTPTAVPANGDTTAAPASTPDAAAETSPTFLSTQPGPDHHWRVTLKDKVIAITGANRGIGLGIAEVCLANDAAAVFSLDLFEPGDEFLALQAANPKRLGYIHCDVTSEESITSAIDAIISKRGAIHGLVANAGMTKHQPALDFDRAQLDKLFNLNVFGAYFCATTVARRFIELGIKGSIVFTASMTSYRPNRAAPSAPYGATKGAVRNMAHTLAMEWAKHGIRVNSISPGFVKTAMTYFVDQAPDWDLKMQYYGGMPRLADPKELGGAYVYLLSDGGSYTTGIDIPVAGIVGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BU96</accession>
    <name>X0BU96_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BU96"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK82074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="33854" checksum="902D29FD4ABD6D74" modified="2014-05-14" version="1">MFWTKEQDFNPKDMPSLEGKVILVTGATAGLGKEAVLQFAHHNPQRIYLCGRNLQKSQLAAQYIKHHVPSASIRLLHLDLCSFASVKEAARIVLSECERLDILMLNAGIMFVPLGRTADGYEIQFGTNHMGHALLTKLLIPLLNKTTRIPGSDVRVVCLASHGHVYLNKGDINYDTLKTDGESVGLYQCYYQSKLANILWARQLAKKFPHFTVSAIDPGLVNTELLVKATGMVWYLYAVVRCMLITPVAKGVRNQLWASVSKGVVSGEYYEPVGKHGLATEEGRDDELAEKLWEWTESELATVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV60</accession>
    <name>X0BV60_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_13263</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV60"/>
    <dbReference type="eggNOG" id="ENOG502SI33">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004083_5_3_1"/>
    <dbReference type="OrthoDB" id="2269373at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK82394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="621" mass="70153" checksum="514C631C6814759F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVJ3</accession>
    <name>X0BVJ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10324</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVJ3"/>
    <dbReference type="eggNOG" id="ENOG502RMBE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2121293_0_0_1"/>
    <dbReference type="OrthoDB" id="4964965at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="115" mass="12881" checksum="84397EEED917B1CD" modified="2014-05-14" version="1">MCTYSFQRMVCCCAKGPECPQMTRGRAIIGGEAFHYIDMFYAVDDLGSACDYQRRLFGRNAGPTMHCPRYAFDDKRIIKGSFRKSELACVKCAETCAPPSCSWQAPRAEGKEEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVZ4</accession>
    <name>X0BVZ4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVZ4"/>
    <dbReference type="HOGENOM" id="CLU_2386258_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="94" mass="10201" checksum="BE4FD1FF991FBF0F" modified="2014-05-14" version="1">MMPGPSGVACIKGPVLHEDAWLKRGTAPHDGSAELGCPQWKLTETLSLGRVNVLMMSIDRSMNDCLFNDIKSVGLGLDCAGVDMQRRMEKKKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWE2</accession>
    <name>X0BWE2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12939</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWE2"/>
    <dbReference type="eggNOG" id="ENOG502QT50">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079101_0_0_1"/>
    <dbReference type="OrthoDB" id="1915122at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040153">
        <property type="entry name" value="Rcf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28018">
        <property type="entry name" value="RESPIRATORY SUPERCOMPLEX FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28018:SF3">
        <property type="entry name" value="RESPIRATORY SUPERCOMPLEX FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="6">
        <location>
            <begin position="88"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="228" mass="25670" checksum="B510A59096154F76" modified="2014-05-14" version="1">MKILTKEEEEAHYAEVVKGGLIGGTLFLGLGLGGVYYASKRYPTFRGLTLPFRAFLVTSTGTFGAIVNAERWSIAYQIAQDPKRNYQDQAARTAQLIRENESAYERFKSYAKENRYPIVFASWLASMGIAFAIVSRQPMNTANKIVQARVYAQGLTLAVLLVSAVFEMNDLKNGDSRWQTIRVVDPNDPTKIIEKKIHKEEYEGQDLWKDMVAAEERRLAAKKQAAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWK2</accession>
    <name>X0BWK2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_12845</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWK2"/>
    <dbReference type="eggNOG" id="ENOG502SIF1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_3_1_1"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="5"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="318"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK82884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="469" mass="51706" checksum="FBE0530E9C69A015" modified="2014-05-14" version="1">MGNFRVCIVGGGLAGSLLANGLINNGVDTMVFERDEETLKREGYQIRLGDPALTGLASCLTDSQLESIVQKLGRYSGSSKTAPSICNTKFQTILDLSALPTYSKSSAINRVVLRDLLLDPVIAEGRVKFGKHFSHYEIIEDGPSGNESVKVNFTDGSSEYCDILVAADGSGSKINKQIGAKNLVDIKSHVSFLSKGNATKERLRQLPPRLLNGPILVFKNGISLYYALYLPASQQKNGDQDQDDDFDFDENQASFYWSLSVPRELCPFDNPSDIPDRRQVCLDIVRDWAPEYHVMLSAGAGDEDNITVTRLRASTKLSKDWRRRLQAHNGNVREEGHPRVWLVGDAVHAMQPTRQVGIRGMGGNQAMRDIADMLPQLLELKRAAEAGPPLSTREIETRCNAYEKNMIDRSFAWVAKSGGTSQPIEELESADFLKTIDLDGLLGRVISFLAGLLLPVATILYKTAKRSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYI0</accession>
    <name>X0BYI0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYI0"/>
    <dbReference type="HOGENOM" id="CLU_104266_0_0_1"/>
    <dbReference type="OrthoDB" id="4589291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="206" mass="24027" checksum="2F8B33A5ADACE593" modified="2014-05-14" version="1">MASQTQNPPPPPSYQEVTSTKLWKVDLWFGSDPDLVRETIPQVKLNIGWQAHLELSTTDIVGLMREGLYVCQENVIVQESCMTVRPYQQEHQTYYYDRHFALTGPNWKGNLVVTTLSCPVATNFRVEHLSADKIFRSYASDISRTQCWVYHFMINNPKVNANYILDDTPLKGLWPWPRNEHIIQGREEEREQTKERIEEGDMLDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1A0</accession>
    <name>X0C1A0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_10925</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1A0"/>
    <dbReference type="eggNOG" id="KOG2204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003818_0_0_1"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF89">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936707" description="alpha-1,2-Mannosidase" evidence="10">
        <location>
            <begin position="33"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="464"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="550"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="383"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK84963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="560" mass="63478" checksum="D6D3FBB6F1F0170A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C286</accession>
    <name>X0C286_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C286"/>
    <dbReference type="HOGENOM" id="CLU_3299394_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="40" mass="4389" checksum="5245F4FD8626FF0C" modified="2014-05-14" version="1">MRLNAYGKVPLKNADKTLSPWGSTASHRTNWLASRGSGMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C422</accession>
    <name>X0C422_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658597">
        <property type="protein sequence ID" value="EXK77512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C422"/>
    <dbReference type="HOGENOM" id="CLU_2979143_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="58" mass="6655" checksum="B3CE8946B1E37490" modified="2014-05-14" version="1">MQTDRRPNQIDHSDLLPDESVTPVLQGFTKGNPEVTCSTRWTQGSEKQWQIDIKAQNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4X9</accession>
    <name>X0C4X9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_17486</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658568">
        <property type="protein sequence ID" value="EXK77817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4X9"/>
    <dbReference type="HOGENOM" id="CLU_009665_2_1_1"/>
    <dbReference type="OrthoDB" id="10016252at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="11"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK77817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="442" mass="49054" checksum="41CFF19C5FA8C04A" modified="2014-05-14" version="1">MVTAATPLPAVVIVGGGPVGLLLALLLAQKGIRSAVLEKDEALNKSPRAVAFSGPIHHVFQEVGIYDTILHDAAQTPGFCWRKLAEDDGEGGKRLGEKVAEWRLGEPNESGIYNPGEYVLQYPQDKIGQLLLHRALETGLVTIHFGMELYAVNESKDGVVAHVRSKKGNLEVQGQYIVGCDGGRSVVRRLMGVKMLGHSWPERFMTTDIVRTPPVVEEVNIDYIVNPDYWAISTPLERARPGKRALWRYSMAITDDDIPDEEVIKPEFINQMLLKHVDGPRPADFEVLRVNLYRMHQLLASTMFRNRCFLAGDAAHLTNPIGGLGLCTGMLDADALAQTLDLALNRYSCEPEAQEECFTAYTSARRRVFQTVVHPTSSAAKTRLQCGNPDDIAKEDWYMRTLCKGNRSAIDQLHDGLINHWRTNMAAELMDSKDQAHSTVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5G0</accession>
    <name>X0C5G0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5G0"/>
    <dbReference type="eggNOG" id="ENOG502RR72">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064039_0_0_1"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052358">
        <property type="entry name" value="Aro_Compnd_Degr_Hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563:SF2">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936185" description="Amidohydrolase-related domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="41"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="326" mass="36113" checksum="8D7034C6F6D72709" modified="2014-05-14" version="1">MLIHLFVANCLFISQVLARVTSSSNVCSSKPDSRMPNGSWDSHLHVLDPVRFPPIPGSYEFGTYTAWDATIEETRLGCSHMVLIQPSVYGNDNTLLIDTLKAFGPNRALGVIVFDVANTSAAQLQEWNDLGVRGVRLNFQSTGDAPPAKELRDMMQRYADAIRPFSWVLQIYIAMKDIPTIEPVIPTLGVKVVIDHLGHPDIPKSNGSGTALDPHTLSGFDSMLRLLKGGNTWVKVSAVYRLSQAPGPLYTDLDPIILEFSTAAPSRLVYASDWPHTRFEGLDIKPWTSHLLDLTGERTELRNKLFRDNAQELWIGNQTASNSAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5W2</accession>
    <name>X0C5W2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5W2"/>
    <dbReference type="HOGENOM" id="CLU_2740065_0_0_1"/>
    <dbReference type="OrthoDB" id="5099377at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="71" mass="7410" checksum="1F0CCA9BA9837881" modified="2014-05-14" version="1">MAAVSGRELLLSRLGFSGSLLCVEGPDGQQQVAATQTSRPRSAPKSGARAISSASAVVLNVGRHRWMVCDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>X0C882</accession>
    <name>X0C882_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Elongation factor 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Eukaryotic elongation factor 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_07141</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C882"/>
    <dbReference type="eggNOG" id="KOG0062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1242">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002848_0_0_1"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18626">
        <property type="entry name" value="CD_eEF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000076">
        <property type="entry name" value="Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.990:FF:000001">
        <property type="entry name" value="Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000193">
        <property type="entry name" value="Probable Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015688">
        <property type="entry name" value="eEF3_ABC2_chromodomain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040533">
        <property type="entry name" value="EF3_4HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047036">
        <property type="entry name" value="EF3_4HB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17947">
        <property type="entry name" value="4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 18" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="repeat" description="HEAT" evidence="15">
        <location>
            <begin position="96"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="15">
        <location>
            <begin position="176"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="17">
        <location>
            <begin position="435"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="17">
        <location>
            <begin position="678"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="986"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1032"/>
            <end position="1043"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00050030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00050045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK90326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1055" mass="117125" checksum="B0F0EB0EDC85087D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8V2</accession>
    <name>X0C8V2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_08971</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8V2"/>
    <dbReference type="eggNOG" id="ENOG502RNUK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_0_1"/>
    <dbReference type="OrthoDB" id="5417844at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="41"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="289"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK87633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="359" mass="40554" checksum="0F58B66D2EC19968" modified="2014-05-14" version="1">MVVDGGNVTYDEAFLNESRQNEVYATQIAFFALMMIIVPCRFFSSRLTKKTLSWDDWLAYFAAFNTVGVFITSMLWLRFGLGRHLAWVMQDDSKNIENFFKAIVANEILYTTALACARLSLVAFFYHIFGVSSMRYFLHGFVAFIIVWAISTYVPSIRTCWPISSFWDGTNQNCIDLSKFYVGVAIGGIITDVGLMIIPLPYIWALKVPLYHKILIAIMLVFGSFACFVTIIRLTKVITVDLTDPTWGTVDLMIWTGMEVYSAVICCCLPTMRPLIKLFWKKLGLKQLSSTGNTDPSKPVSNGTGMWGNKSRQNSRHLTDGVPASNADEMELTKHAYYELHSDNAHGRSQDSITVHQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAE0</accession>
    <name>X0CAE0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAE0"/>
    <dbReference type="HOGENOM" id="CLU_3399406_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="31" mass="3650" checksum="3DB2D98A95DE34B7" modified="2014-05-14" version="1">MQMQMQSRHKPKTMINMWAAVDEGKGIFAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CC89</accession>
    <name>X0CC89_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08119</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CC89"/>
    <dbReference type="eggNOG" id="ENOG502QWBF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013756_2_1_1"/>
    <dbReference type="OrthoDB" id="3026777at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK88833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="55914" checksum="659FDBB8485A9EB1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDG6</accession>
    <name>X0CDG6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDG6"/>
    <dbReference type="eggNOG" id="ENOG502S24K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041456_2_1_1"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF241">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="7">
        <location>
            <begin position="80"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="10"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK88874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="304" mass="34047" checksum="B2A913B608CCD292" modified="2014-05-14" version="1">MLSNLASKLGLASKPGLASKPASQSFLKPRDPSKNMLTKVDYTSNDILIPDSFLSSPPEKPITTHPIDFANSPLPQYDGHTAIVLDNVLSPGECKELLSLAEASVPRPDESAPAWKPALISAGPGWEAPAPGYRESDRIIWNQQTVVDRLWERCMLSEGLRELLAVVPPQPYMKGGKWVFSRFNERMRFLKYSPGQFFKPHCDGPFYYTEGPGKEFETFYTVHLYLNDSVENDPASELEGGATSFLDRKGEKRVDVNPKTGSVLIFQHRGLFHEGATVHKGIKYTMRTDILYEWVPDKETEEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDT9</accession>
    <name>X0CDT9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDT9"/>
    <dbReference type="HOGENOM" id="CLU_2399760_0_0_1"/>
    <dbReference type="OrthoDB" id="10276772at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="93" mass="10985" checksum="9C702AE78B1EA571" modified="2014-05-14" version="1">MQINVPHPLLTFQVPRPIGEPLDLGNEWGDKLTSSDALDLKSEWCSTSLSFAKICCDDDVRCFVWWNSHYTQYVHYHDNSYIVGLRLKMRRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDX5</accession>
    <name>X0CDX5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Salicylate hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_07523</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDX5"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_3_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000115">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF238">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="17"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK89418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="436" mass="48676" checksum="F9100132DBABF7A4" modified="2014-05-14" version="1">MPSSTQPSQAHDDANLNVVVVGAGLAGLAAAISISLSGHNVTVLESAKELLEVGAGLQVTPNCTRILQKWDLPDRLWQSAAEPTSLVVHRYSGRTLAIEPDFHKHIRKKYGAPFIDLHRVDLQLALYDKAKELGVQFKLGDRVQDIDFSIPEVSTEAGARYTGDLIVAADGLWSKCRSKFLGSEDKPMPTGDLAYRVVLDAKDIHDPELREWVEHPTVHFWIGPGAHAVGYSMRGGQMYNVVLLVPDDLPSDVSRQAGSVEEMRELFNDWDPILARFLSQVDKVDKWKLMHREELDSWINDDSNFVFVGDACHPMLPYLAQGANSAVEDGAVLGLLLGHVKSKHQLPKALSMYERLRKSRGEAIVRETFKQRESFHMPDGPAQEARDETFLSQLGAEELKGPFPSRWTCPQVQPWLYGYDAFEVVEDAVKRDPFTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE82</accession>
    <name>X0CE82_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658432">
        <property type="protein sequence ID" value="EXK80947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE82"/>
    <dbReference type="eggNOG" id="ENOG502SIBV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035510_0_0_1"/>
    <dbReference type="OrthoDB" id="640151at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="554" mass="62010" checksum="95E73D0ECDF8DE51" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEQ1</accession>
    <name>X0CEQ1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658430">
        <property type="protein sequence ID" value="EXK81117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4405280at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36519:SF9">
        <property type="entry name" value="EB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36519">
        <property type="entry name" value="FIP (FUNGUS-INDUCED PROTEIN) RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="629"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1187"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1256"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="447"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="640"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="671"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="766"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="787"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="873"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="888"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="913"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="957"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="983"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1042"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1053"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1064"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1083"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1738" mass="165062" checksum="1A8C49D57A85B357" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF36</accession>
    <name>X0CF36_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH-ubiquinone oxidoreductase 21 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14361</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658428">
        <property type="protein sequence ID" value="EXK81217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF36"/>
    <dbReference type="eggNOG" id="ENOG502S1BF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087364_0_0_1"/>
    <dbReference type="OrthoDB" id="196140at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053229">
        <property type="entry name" value="NADH-Q_oxidrdct_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024549">
        <property type="entry name" value="NADH-UbQ_OxRdtase_su21_C_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019721">
        <property type="entry name" value="NADH-UbQ_OxRdtase_su21_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34062:SF1">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 21KDA SUBUNIT N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34062">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10785">
        <property type="entry name" value="NADH-u_ox-rdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12853">
        <property type="entry name" value="NADH_u_ox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 21kDa subunit N-terminal" evidence="2">
        <location>
            <begin position="22"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 21kDa subunit C-terminal fungi" evidence="3">
        <location>
            <begin position="116"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="188" mass="20854" checksum="B0A28C931BA0B77C" modified="2014-05-14" version="1">MAETATKQSTPSFVGTSKVVQTEYPLIDNDPHFKRVVGYARTSDYIAGTVAAAFAPAALYALEKFAPSHVGKGGFPKAMRLAGGVGLLGGFLYFYQRSALRFYGATENAREIEMDMREMVDKVKKGEPLYGVSRLSPHLQGVAARQSRYSALFLSTIPWFNFVNHNQHGVDTAKYYQQAERELEAERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF98</accession>
    <name>X0CF98_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_07599</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF98"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006909_5_2_1"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK89504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="530" mass="58548" checksum="DBF54C989A6199B1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFA0</accession>
    <name>X0CFA0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">5'-3' exoribonuclease</fullName>
            <ecNumber evidence="17">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">FOQG_05132</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Possesses 5'-&gt;3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.</text>
    </comment>
    <comment type="function">
        <text evidence="15">Possesses 5'-&gt;3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II. Essential for vegetative cell growth and chromosome segregation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Interacts with RAI1; the interaction is direct, stabilizes RAT1 protein structure and may stimulate its exoribonuclease activity. The interaction also stimulates RAI1 pyrophosphohydrolase activity, probably by recruiting it to mRNA substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="17"/>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFA0"/>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1050:FF:000002">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000003">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000005">
        <property type="entry name" value="5'-3' exoribonuclease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017151">
        <property type="entry name" value="Xrn2/3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF41">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037239">
        <property type="entry name" value="Exonuclease_Xrn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10 17" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 17" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 17" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0806">Transcription termination</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="18" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="20">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="413"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="507"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="861"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="540"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="19">
        <location>
            <begin position="867"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="907"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="19">
        <location>
            <begin position="983"/>
            <end position="994"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00046137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00046943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR037239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EXK92866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1005" mass="112959" checksum="8A26B364E95EBA7B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHL6</accession>
    <name>X0CHL6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TPR repeat-containing protein P27G11.02</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHL6"/>
    <dbReference type="eggNOG" id="ENOG502RZH4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027223_0_0_1"/>
    <dbReference type="OrthoDB" id="10050400at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031942">
        <property type="term" value="C:i-AAA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24145">
        <property type="entry name" value="Mgr3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040201">
        <property type="entry name" value="Mrg3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142:SF1">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK90743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="58454" checksum="797887AC55E81E45" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKS0</accession>
    <name>X0CKS0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658405">
        <property type="protein sequence ID" value="EXK83142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKS0"/>
    <dbReference type="eggNOG" id="ENOG502SJHH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037349_0_0_1"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="372" mass="41912" checksum="8EA4AB3CB1465A0D" modified="2014-05-14" version="1">MMDGDQILMIYHTSGSTSGAPKLVPITARWMECLIKKFSSFSEFLPLPRAMVKVAIGSSTHMGSTMLFLESDLQGGCFIIPTSIPYPTSELVDMIDNHGLTRLDMFPVFLSQLFRQARHDPLLFRSLCLLDHIAYGGYPLDPYEEAWAHGHNFYLISAFGFTEVGLNLISYGAKEVALGPVSPSIFEFVPLGDDQNAQEHLVELAVPPESPDCPHYSLRDATDGKFHTGDLFLKIALGEYAFRGRDDDWVKMEMALRCDANSIEVDALQCCGDDLIHAVVAIGVGRPSPAIVLGPKHDDVLESTEKTRELQLKVLQRITPFHRRRHKHERIEDVNLIFVVPQRSLPRTDTKGNIRRLKVEEQFKQKLDEMFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKY4</accession>
    <name>X0CKY4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKY4"/>
    <dbReference type="eggNOG" id="ENOG502RMFR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_634675_0_0_1"/>
    <dbReference type="OrthoDB" id="5099851at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="372"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="430" mass="47559" checksum="FE5A4B7B46283E8A" modified="2014-05-14" version="1">MGKNKKKNKNKTKNGEQQGEGSKNAAASQKGTPTTTEDVQAAPDMDCPPYSLSPPPNIPLAVQYHRNMVYHLLQANITLEDKERSVSDTFVTTRNASERVAMERIATFFGISPGVKKSTVSDGSEQDLNENIRAFIRKGVQSGHITEQDIESFVTEQIVPFEGPTSYAAFSQIQTYLAQCGVPFVHHRTSVSSGSAPGCSVRSYMAQKVPSKIIEVNESPNTYKITNAKEEDSQTGSMVDNPVHKSDKSVEEEVEVAESDQLEHSNPEDTNSINANCSGYQAQKKVDDRSPVSDVASKEKVDEGDGHGSQTTEAPQLDDLDAQDTEPAVVGEDESRGNEPRSDTIGESDYDAYERKTLESCEAAVEQSSFHKQRAQEQLEHATSKISQCDEVAQHAAALRRLVKQRREMENQMDYHEREIQDLRISIQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLL4</accession>
    <name>X0CLL4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell wall integrity and stress response component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03931</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLL4"/>
    <dbReference type="eggNOG" id="KOG4157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2537459at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936483" evidence="3">
        <location>
            <begin position="28"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="27"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK95330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="368" mass="38751" checksum="D9C10A1529C9568D" modified="2014-05-14" version="1">MSPLSRHAQQAGLLVLIASSWAPLAAALDIEYCASYNTGETPRNTSIYQTNGLCHDFCIDDWAFAITQDKLCWCSNYAPVKSTQEDNSKCDTPCPAWPDEVCGGNGVYGYVSLGKVEPSGSRGPSPSSTKAKPTTVAVSRVTETIQNTVTLKPSSTSISTSTSTSSSEPETTSTTEDETSATSTAEDESTTSSSRTSVVQTVTAGGTIRTVTVAAPTETGGTTASENTNGSTTEKSGLGTGQVVGIVVGVIAAVIGAAALALFLWFRRKKQQNEQEAYQDDPSVRDSSSGIARPDMSMAGSPIASAAAGSRNSTLQVDPRMDPFKQGLYVRSASHESINTLRDDHDYSRRIQAPKVLRATNPDPTPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMY8</accession>
    <name>X0CMY8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMY8"/>
    <dbReference type="HOGENOM" id="CLU_128317_0_0_1"/>
    <dbReference type="OrthoDB" id="3262926at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="180" mass="20109" checksum="3FC11B5A94F3C784" modified="2014-05-14" version="1">MAMSKPASEQELAEKRRRELKASIILTELAKRHRRKLEGPLDTTEAVAQAAGISSPNGCAISATDSSGKVGSFFKINAINKTTIEAYLRAKPSLTTFVPIFIPCNPARKSLSSHSLHPTLGIETTLPHRRLEHLHDEPRPAQNEYPVWYFVYGDLAEGDVLFDLLGCERHSEILRLLEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CND0</accession>
    <name>X0CND0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CND0"/>
    <dbReference type="HOGENOM" id="CLU_035151_1_0_1"/>
    <dbReference type="OrthoDB" id="4636359at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="461" mass="54246" checksum="6E841154AB141641" modified="2014-05-14" version="1">MDPFQKLPAEIRIKILGSIPSHATTARLIRASPIMLAQYKTTESANLLEYLSQLVGTNINDHELLQDALAIIYFSRTHGIDPICDLMRDWKAKTLPLPFHRGGKGMITKLRLLFERMSEFIDDYLSKATAQNTVEAYLQPPRVTYMDTVDPQRITLHDLNSQERLRLFQAFIKFEVLCKLNSQRVHSALTTIPLKLVPELNSWEEKALMSVYEYMRASYSAIFAQCAGVQAFKQYKKTCDHLRRTKREESFFLETMCFDPHYPFLRHQFPAYSVAYPEVLPWCGFDVLSHLMMEAKKAKRTPIWIARMCSRYDRRSYDWAQHTIRKIVENLSWEEERAQLNNRLARQSNRTDTEANQATRTQRTIYQQRAWEFFDDARFCPGQEAHFPTEEEIKTEIARLKNERMMETRRQWKEYFDKKRSSPPWYKSPTKCESYTAVMKLEEDREISDGGLTAPPFFALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNM3</accession>
    <name>X0CNM3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">26S proteasome regulatory subunit rpn-8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05156</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M67A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNM3"/>
    <dbReference type="eggNOG" id="KOG1556">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027018_3_0_1"/>
    <dbReference type="OrthoDB" id="10256771at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08062">
        <property type="entry name" value="MPN_RPN7_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000004">
        <property type="entry name" value="26S proteasome regulatory subunit rpn-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033858">
        <property type="entry name" value="MPN_RPN7_8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF7">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="16"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="298"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="328"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK92898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="344" mass="38314" checksum="57A47990D4CB3BA3" modified="2014-05-14" version="1">MPTTTAETLSLVTRNVTVAPLVLLSAVDHYNRTVSTKTKRRVVGVLLGQNDGNDVRVSNSFAVPFEEDEKDPSVWFLDHNYVESMNDMFKKVNAREKLIGWYHTGPKLRASDLEINELFKRYTPNPLLVIVDVQPKESGVPTDAYFAVDEIKDDGTTTARTFVHTPSVIEAEEAEEIGVEHLLRDIRDVAAGTLSTRVTNQLQSLQGLHLRLRDIGTYLQKVLDKQLPVNHAILGNLQDVFNLLPNLSTPEGDGKSGGGELAYAMSVKTNDQLMAIYLSSLIRAITAFHDLIENKIQNRQQQEEKEAKKEEINGKDEKKEGANGSSGDSKEGAEKDKENKETKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNM6</accession>
    <name>X0CNM6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05160</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNM6"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039068_1_0_1"/>
    <dbReference type="OrthoDB" id="506498at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="PiNMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF11">
        <property type="entry name" value="GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="5">
        <location>
            <begin position="94"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif I" evidence="4">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="4">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK92903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="329" mass="36546" checksum="7544ED39D114FA13" modified="2014-05-14" version="1">MAAAAVSDQTTDLSKQYDTPLGLAHSTMQVLKDRIKLHYDLASDYYLSLWGEHIHHGYWPTPESEATQTKEEAQANLIQLLLDISNLPSDSSVLDVGCGIGGTSRYLASKHGSSVTGITISSKQVEIANRLTKAAIEDTSSSDVSDDNGFTKLGEGKVKFLELDAEKMGDFFSDQQGTFDAVWISEALSHFPNKALFFENVMKVLKPGGKLVLADWFKDEDVDDTTFINDIKPIEDGMLLPPLCTQQGYVDLAKKAGLKVLSEPKDISQQVRKTWDITWSLVQNPSLWAFAFTQGRDGIAFLQSFRAMRRGYANGSFRYAVMVFYKEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPQ1</accession>
    <name>X0CPQ1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11302</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPQ1"/>
    <dbReference type="HOGENOM" id="CLU_1214796_0_0_1"/>
    <dbReference type="OrthoDB" id="5091869at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.30">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="N1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="160"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="228" mass="24967" checksum="E123E51C76AD943D" modified="2014-05-14" version="1">MSALTSEALRQLDQLNNQGGLPSPSPTQDKWETDSDCSYYSLSDLTLDKWYRQIPASQVRKQAKQIPASPVSSQSIYPRRFHNKEELDLQSSGPWQEYPFCLNKGYVSGSPGPVRIITNSAGSGEFDVVYHPGRTERSACLANYRPKGYQKGAVPKPLPSSELSSQSTSSSSVGGSSLQHSPYIAAHLAGYQQGLSAAYYAQSPPPAYVVPVPLVTYAYLPVYGQYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR60</accession>
    <name>X0CR60_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR60"/>
    <dbReference type="eggNOG" id="ENOG502SQW6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081916_0_0_1"/>
    <dbReference type="OrthoDB" id="4500473at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="284" mass="31483" checksum="22793D81B84F2860" modified="2014-05-14" version="1">MEKVWFKLRQADYPPPPEDAILRGDGDDSAAPLCLGHFISNLKTLDFPLNHGSILPFPTRMRVFCNTTLNFTWDDTRLRSPGTNLAAGAPILAAIGVTAKASLQFAFMKTVESHEAYDRLDTYIVQPTKGYIEDCLEQDQLQAYVKGKISWSVFMITGIKVARAGKREAQEETNVAADIGPELDLPLVATMRATATNKRIASQRVSGEHPGDFIWAIRLAKIHKGLLMKDWSVDPYTKRATFAGGDESELNVESVLRDEGLEGFTIVEDDKLDEVVILDEGPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRJ8</accession>
    <name>X0CRJ8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Eukaryotic translation initiation factor 3 subunit E</fullName>
            <shortName evidence="4">eIF3e</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">INT6</name>
        <name evidence="7" type="ORF">FOQG_02399</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the eIF-3 subunit E family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRJ8"/>
    <dbReference type="eggNOG" id="KOG2758">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031132_0_0_1"/>
    <dbReference type="OrthoDB" id="417252at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071540">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3e"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21378">
        <property type="entry name" value="eIF3E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03004">
        <property type="entry name" value="eIF3e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016650">
        <property type="entry name" value="eIF3e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019010">
        <property type="entry name" value="eIF3e_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10317">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09440">
        <property type="entry name" value="eIF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21357">
        <property type="entry name" value="EIF3E_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016255">
        <property type="entry name" value="eIF3e_su6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01186">
        <property type="entry name" value="eIF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="6">
        <location>
            <begin position="245"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR016255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK97070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="439" mass="49945" checksum="626EDC93DEB38AC8" modified="2014-05-14" version="1">MEDVLNAVSADGSSIMPRLAPHLSRHLLFPLIQFESERAEEQGQDAKAKEILSGKIKLLEDTNMTDYVATLYCELHGVSEAPEQYNKKRQEVLSQLENYEQATAKIADLLTQDEVVNGLRSDKVANLEFLKNQHGVTMEMVNALYDFGQFQFRCGQYGPAADMLYQFRVLSTDNDKVSAATWGKLASEILQTNWESAVDELKNVRENIDSKLFNNPRAQLDHRTMLLHWSLFPLFNWEGAREPILDMFFSAPYINTIQTSCPWILRYLIAAVITGRGRARNSSIQQKQIKDIIRYVRQEAYEYTDPITQFVNALYIAHDFEAAREALSMAAEVCRSDFFLASSADAFVDAARHLICESYCKIFSRMNIRDLSAKLGLNPDDGEKWIVNLIRETRLDAKIDSQDGTVVMNHPPNNVYQQVIEKTKGGFFRTQVLNAAVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS14</accession>
    <name>X0CS14_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L27-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS14"/>
    <dbReference type="eggNOG" id="KOG3418">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067359_0_1_1"/>
    <dbReference type="OrthoDB" id="2365484at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.770:FF:000001">
        <property type="entry name" value="60S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK96936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="135" mass="15705" checksum="379AACC99944F2C0" modified="2014-05-14" version="1">MKFLKVGRVAIITRGRYAGKKVVIIQPVDNGNKPHPFGHALVAGIERYPSKITRRMSKTRQEKRNKIKPFIKVINYNHLMPTRYTLELEGLKGAVSNDTFKEVSQREDAKKTVKKVLEERYTSGKNRWFFTPLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSH0</accession>
    <name>X0CSH0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tachykinin family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSH0"/>
    <dbReference type="eggNOG" id="ENOG502SN1P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_528965_0_0_1"/>
    <dbReference type="OrthoDB" id="4159781at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="58377" checksum="9EBAF8AFFCAEBD1E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSP9</accession>
    <name>X0CSP9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSP9"/>
    <dbReference type="HOGENOM" id="CLU_750146_0_0_1"/>
    <dbReference type="OrthoDB" id="5100771at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="428" mass="48423" checksum="D648C61A713F81EF" modified="2014-05-14" version="1">MPPFAGSVDKDEAVPMAGNPPSESLAGIEEAAPLYLEYITSESTRNDLLSIMPGNNLTTYAFCAVAEGVFQDPCHDSIVPRYLIWSYFEAESDAAKLEILEAITDYFQDPAPGKSRETFIVSPFEDNINFLVRYRAHSHGWSLTVLGPSDLIRDVPAWLVHLLDRIFDIMRLRIPYFEPKGFRWFLHQRFVHFGTDPSNTLFPLMFPRIEEVRSDCFWEFAGKESRSQLYGDGLNLVDCSESMLEDQFAGDEGEGSQVQPRSRDRSRSPPSLRRSSRLKRRRINYSEVSDINVDLRAKSKQSETVELSSPEDAVPDAYGKAPVKTRSTPLVPAFTEADLVFPLTQPDELKLVVLCAGTKLGEAQRCIVFRRRATTGRGAFWPQGCGFRYLRQMLSFLTQTRRTRTVVCWALPRVRPVGKKTCVTCPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU56</accession>
    <name>X0CU56_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU56"/>
    <dbReference type="HOGENOM" id="CLU_2960794_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="59" mass="6332" checksum="84E73F6F771CFC9D" modified="2014-05-14" version="1">MEMDEKKKGLSGRELELEGKTGESGKAKLVGGGGFVGEEKPGVEDRVIPDLKSRTEERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVA4</accession>
    <name>X0CVA4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVA4"/>
    <dbReference type="eggNOG" id="ENOG502S5UU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078844_1_0_1"/>
    <dbReference type="OrthoDB" id="5363135at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="2">
        <location>
            <begin position="73"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK98400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="177" mass="19405" checksum="337B0D355C61E2C3" modified="2014-05-14" version="1">MTEPLSKVDSAVQGLSSSPPAKDDKKTRRQSSAAAPGVYNVNDLEAEGIELELAPETQKTGWKINTSPNTIEDPAILKLHLSKPPVKRIDLHFPLGKEVTARNLKGVTIKDALDAIHKAYKKRADDELDKPYLAGFEWDKEESWTQLVVHLQAQPTSTTLGGPSGGGKKKKNKKQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-11-27" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWV9</accession>
    <name>X0CWV9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tryptophan synthase beta chain-like PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_09326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ACC deaminase/D-cysteine desulfhydrase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWV9"/>
    <dbReference type="HOGENOM" id="CLU_1337570_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019148">
        <property type="term" value="F:D-cysteine desulfhydrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780">
        <property type="entry name" value="1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780:SF2">
        <property type="entry name" value="1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="5">
        <location>
            <begin position="21"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK86962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="205" mass="21411" checksum="2EAD90EC75C6B636" modified="2014-05-14" version="1">MLLKSRENGAGSSSDSELLFPSTGASTHPLGGLGYARWAFELLEQETKLGVTFDVIALVAGSCSTLGGILAGLKLAQKQGITGPKKHLIGFSVLYPKKEDVVEKVLSIAKNAASKIGVSPDEITEADFEIDASYIGEGYGQVNESTADGMKELAKAEGILTDPVYTGKAFNGLLHTAKSGGLKGKNVLFIHTGGQAVLGAYPQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXQ5</accession>
    <name>X0CXQ5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXQ5"/>
    <dbReference type="HOGENOM" id="CLU_2941852_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="60" mass="6862" checksum="2F1F66E5652E6CB9" modified="2014-05-14" version="1">MNTLLMKEHGTSNIMSVILKLWEPPTLNSLDYVCQRQPRVVGFQLMAIRYARQTEASALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXQ8</accession>
    <name>X0CXQ8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tetraspanin Tsp3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03247</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXQ8"/>
    <dbReference type="eggNOG" id="ENOG502SP07">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055673_0_0_1"/>
    <dbReference type="OrthoDB" id="71600at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK96078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32616" checksum="1930B1136FECF76A" modified="2014-05-14" version="1">MLIAILPLGFSCSSTRNNMIHLTVLYLILSLVLLVIAIIVHVRSSNLSLAISPTLSILTVVLPVLGFLNTAFYPSIRRATKSSSSGVAKLAPLIVQVLQALITTILATLLLERAVPSEMMGCMLDKKWMGMFRAHDARSIRYIQDAFDCCGLNSIRDRAYPFPNTAPSNCAETYGRRSPCREPWSGALQKLSLLDLCVVLVVGLIQILGLLLTKKDSSWLSNWRNHDRGQSEQHRDGRRPLLIDRERDVIEEEETAPERPERSSPGYGSVHENESGPRVVPSAVIERNNWTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYF4</accession>
    <name>X0CYF4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYF4"/>
    <dbReference type="eggNOG" id="ENOG502ST1T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082183_1_0_1"/>
    <dbReference type="OrthoDB" id="3880401at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="219" mass="24650" checksum="D0B201F5646D2491" modified="2014-05-14" version="1">MFFIMQNSSELLYHIILTVIDFHLEPSGSQRAIYILGTRATIEAAKDSAFKVLHTLRYKPDDFVEYAVHSRHVGTWDHGDGVLIYAKAPAGQVFLVSIQATPNNELLQADRDGAILLPHGVPSLHYVTQTVIDYNKDRTGCVQQMQIEGTFVHRADARKAAQKLLDPLDYVEYDTPEKMKGEWPYGEDILIHAVAETGENTTIEIKTVVDTHHKHGKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ67</accession>
    <name>X0CZ67_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ67"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_49_0_1"/>
    <dbReference type="OrthoDB" id="294702at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45763:SF46">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45763">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="315" mass="34720" checksum="E3DABC91BF10019B" modified="2014-05-14" version="1">MDDHQDKIATLADGRKVSYAVYGAQDDDAPTFFYLHGFPGSHHEGYVINTTAAQYGVRVIAPTRPGYGDSTFQKNRRILDYPKDILELADILSIKQFAVLGVSGGGPYAIACLKDLPPDRLVGIGTAAGVMPMSFSTQGMLTMTRLMFNIAPYATGILGWITDRVLGNTARDTKHPEKLEEMMDKDISARSASDKDVWETHPDLRKSLGRATREAMKQGGYATAWEARLFGSDWGFKLEDVKVEKGRMIMWHGDLDVNVPIGVSEKAVQLMPGAELRVMKGESHMSLMTRVDEFTVAMKDMILRSGPGPNGRSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ92</accession>
    <name>X0CZ92_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ92"/>
    <dbReference type="HOGENOM" id="CLU_005533_5_0_1"/>
    <dbReference type="OrthoDB" id="2410195at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF8">
        <property type="entry name" value="O-METHYLTRANSFERASE AF390-400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="204"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK96623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="374" mass="41595" checksum="65E46819D0E9382E" modified="2014-05-14" version="1">MGSVGPSTYDIIATLDAVSPSQFGGDEFERLRVRAAARRLLARVETPHERVWGFCFEHPAVFAALQTAIDLGIWKAWTKEGRLFRLLAAFYVVEEAGVDTFKPTPFSYIIGDESTKVRASLEAATYQYISAGQNLPKHLAKIGYKVPTAEDNNYAGSDPDGLNFFGRLQKSPEYYEAFTGHMEAWTSWKTPWTKIYDPSNLIEGADLSKPLVVDVGGNTGIDISHVLKVRPDLPKGVLVLQDLPEIIERADVDEKITAMAHDFFKPQPVKGSRAYFMHAVVHDWPDAQAIQSLQSTKDAMTKGYSKLFVYDIVLPPTGASISQTTMDVQMLSLLSASERTKNQWEELLTGAGLKIVKFWPDPQQYEMLIEAGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZP8</accession>
    <name>X0CZP8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_03407</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZP8"/>
    <dbReference type="HOGENOM" id="CLU_006524_9_1_1"/>
    <dbReference type="OrthoDB" id="5226580at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="100"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="532"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="533"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK96329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="733" mass="81113" checksum="CF91F026C9169786" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0D107</accession>
    <name>X0D107_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D107"/>
    <dbReference type="HOGENOM" id="CLU_3392359_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3696" checksum="34ACF3B90D742FF6" modified="2014-05-14" version="1">MHQLQLHRSYKPEKVVPHSRLDFGSIGQHAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D837</accession>
    <name>X0D837_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinetochore protein mis13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D837"/>
    <dbReference type="eggNOG" id="ENOG502S2VJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021697_1_0_1"/>
    <dbReference type="OrthoDB" id="3364649at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013218">
        <property type="entry name" value="Dsn1/Mis13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778:SF2">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08202">
        <property type="entry name" value="MIS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="364"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="451"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK90777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="57911" checksum="C6F976EF72966CE9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8Y7</accession>
    <name>X0D8Y7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein PBDC1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_00082</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PBDC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8Y7"/>
    <dbReference type="eggNOG" id="KOG4093">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103791_1_0_1"/>
    <dbReference type="OrthoDB" id="10248897at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3560.10:FF:000001">
        <property type="entry name" value="Protein PBDC1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3560.10">
        <property type="entry name" value="yst0336 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023139">
        <property type="entry name" value="PBDC1-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008476">
        <property type="entry name" value="PBDC1_metazoa/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021148">
        <property type="entry name" value="Polysacc_synth_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410:SF9">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04669">
        <property type="entry name" value="PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysaccharide biosynthesis" evidence="5">
        <location>
            <begin position="27"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00061201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00069779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK99614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="163" mass="19182" checksum="C683302B87E50F89" modified="2014-05-14" version="1">MDPLDNMAGAPVPKNFDAENAQNNEDIEKQFAVKVVQHMQTYWSILERVKGSSLRLTKIDDEIMEHLKTDFPEFDPAAKVDEDEMKSKAGKERWRKFMMAYEKKVDDYNFGTMVRDRPDVEYEEDTTIFVPRMQFYALEIARNRAGLNDWIYEQAQAQKNKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9G1</accession>
    <name>X0D9G1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Phosphomannomutase</fullName>
            <ecNumber evidence="5 13">5.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_00450</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>alpha-D-mannose 1-phosphate = D-mannose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11140"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="EC" id="5.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the eukaryotic PMM family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="5 13"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9G1"/>
    <dbReference type="eggNOG" id="KOG3189">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065642_0_1_1"/>
    <dbReference type="OrthoDB" id="10264771at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02585">
        <property type="entry name" value="HAD_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1240.20:FF:000001">
        <property type="entry name" value="Phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005002">
        <property type="entry name" value="PMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043169">
        <property type="entry name" value="PMM_cap"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466:SF0">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03332">
        <property type="entry name" value="PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00445">
        <property type="entry name" value="alpha-phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01143">
        <property type="entry name" value="C2.B.3:_Phosphomannomutase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01140">
        <property type="entry name" value="C2.B:_Phosphomannomutase_and_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXL00179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="271" mass="30333" checksum="F5C76BC6D5432596" modified="2014-05-14" version="1">MALASPPSYTPLQERPLKDTICLFDVDGTLTPARLDASPEILDILQKLRSKCAIGYVGGSDFAKQQEQLGKPAGQPVTALFDFCFSENGLTAFKLGEPLESNSFIKFIGEEQYKELANFVLHYVADLDIPVKRGTFIEFRNGMINISPVGRNASTQERNDFEAFDKDAKVREKFVAVLKERFGHLGLTFSIGGQISFDVFPTGWDKTYCLQHLENEAKKPDGIAYKTIHFFGDKTFEGGNDYEIYTDSRTTGHSVTGPEDTMRILKELFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBB7</accession>
    <name>X0DBB7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBB7"/>
    <dbReference type="HOGENOM" id="CLU_3242173_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL00425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="43" mass="5168" checksum="6F0447095D795D31" modified="2014-05-14" version="1">MRLLYLEDQKGCHRYDALTEEAPYYGYRPVQSPVAEKEKKVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBF7</accession>
    <name>X0DBF7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Alpha-dioxygenase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_05905</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBF7"/>
    <dbReference type="eggNOG" id="KOG2408">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033051_0_0_1"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031408">
        <property type="term" value="P:oxylipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09818">
        <property type="entry name" value="PIOX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034815">
        <property type="entry name" value="A_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF11">
        <property type="entry name" value="ALPHA-DIOXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 14" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0925">Oxylipin biosynthesis</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-0611">Plant defense</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK91902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="668" mass="75612" checksum="EC6DA0D15683F8EB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBI1</accession>
    <name>X0DBI1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Translation factor GUF1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_05931</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GTP-binding elongation factor family. LepA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBI1"/>
    <dbReference type="eggNOG" id="KOG0462">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009995_3_1_1"/>
    <dbReference type="OrthoDB" id="1074at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097177">
        <property type="term" value="F:mitochondrial ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03699">
        <property type="entry name" value="EF4_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01890">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000078">
        <property type="entry name" value="Elongation factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000015">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000007">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2570:FF:000001">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000004">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="entry name" value="Elongation factor 4, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512:SF7">
        <property type="entry name" value="TRANSLATION FACTOR GUF1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="TRANSLATION FACTOR GUF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="61"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="70"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="135"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="189"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK91927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="660" mass="73745" checksum="71E1B1F79A120E2E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCJ3</accession>
    <name>X0DCJ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribose-5-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-ribose-5-phosphate ketol-isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoriboisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_06148</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCJ3"/>
    <dbReference type="eggNOG" id="KOG3075">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056590_0_0_1"/>
    <dbReference type="OrthoDB" id="1555531at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006014">
        <property type="term" value="P:D-ribose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000014">
        <property type="entry name" value="Ribose 5-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934:SF0">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75445">
        <property type="entry name" value="D-ribose-5-phosphate isomerase (RpiA), lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK92272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="392" mass="42287" checksum="9B03279DAE2A1A55" modified="2014-05-14" version="1">MKWLSHLSTRKSPALVGTASFLPTNSLMKHYIIPKPSILSSASTYHTFHSTTTLAPGARFFSTQLPYTSPRYLPTTPRHPHRGVLHIPPTHIRSYKQTQGLSLTYRSNPRAMSSAANLVESAKKLAAYQAVNDHLDASYKFVGIGSGSTVVYVVDAIVSKGPEFYKEMTFIPTGSQSKGLIRAAGLNLVNLDERPVVDGLPVPLDVAFDGADEVDEDLNLIKGGGACLFQEKLVAIAAKKFIAVADYRKQSPRLCTTWKTIPIEVLPLSAPDVLTRLRAMGSANPVVRSGLPSKAGECVTDNGMWLIDAPFSPLLLPKDIRSEGDGRGKDGAWEVNALAEELVRTPGIVEIGLFHGFNGSEAVKLGKQLQAQKPIAAYFGLANGEVQVQNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0DE31</accession>
    <name>X0DE31_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DE31"/>
    <dbReference type="eggNOG" id="KOG0199">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006696_0_1_1"/>
    <dbReference type="OrthoDB" id="635774at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="330"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="753"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="718"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="755"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="816"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="859"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="894"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="905"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="943"/>
            <end position="959"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="968" mass="107522" checksum="7E96AD6C76779E55" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0DGA7</accession>
    <name>X0DGA7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inorganic phosphate transport protein PHO88</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DGA7"/>
    <dbReference type="eggNOG" id="KOG4554">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099163_0_0_1"/>
    <dbReference type="OrthoDB" id="18139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008756">
        <property type="entry name" value="P_tr_PHO88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21156" checksum="49E1DD32F6B2A46B" modified="2014-05-14" version="1">MALSPQITNLIIILGMMQVSKRVPFDDPFVLNVVRAVYLASNVIIAALYFYTQLKINKKKDLTTLKYVEPAPMGSTEEGKLVTTTIHAYDNQQIRTAFRGQAMGIAMMAFMHIYMKYTNPLLIQSIIPLKSAFENNMVKIHIFGQPAAGDLKRPFKQPQGFMSAMQGGPAQSDKKAVEAAERAGRGGAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0DMR0</accession>
    <name>X0DMR0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DMR0"/>
    <dbReference type="HOGENOM" id="CLU_1283319_0_0_1"/>
    <dbReference type="OrthoDB" id="4754366at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="215" mass="23835" checksum="30E52B021323EDCA" modified="2014-05-14" version="1">MFKQIQPAAQVDSMIPSPELPIRKAFTAFPRPPSQQMPVMAPGLDPGQGKLSRAAFCPRNSVLIDHPFNPPKTYRYERTTRQARGHEPSTISTPSKRTHVDEDDDDPSDEALAHAKHLFHRRRPVSESTTADNVERITQPTPEGWSAEDETVVSGSWDGSSAKIYSAKINQGQHAAFLALFKTSIRVLGLAPITMISPIHCLRYQPVSRDNSGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0DP07</accession>
    <name>X0DP07_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DP07"/>
    <dbReference type="eggNOG" id="ENOG502S6PS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_7_1_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="40313" checksum="3C704271011B8B78" modified="2014-05-14" version="1">MPETDSHSFSIISEPGIETIYTPTDQDTDEYELVFDDARSECLQQDDDSSCCTSLAASIFDYEHSHGRRYHAYLAGRYPLPNDEGEQCRELAEHFLMQQLLNGKLFLSEVDKDAKKIIDLGTGNGAWVIDMADEYDKTSVIGTDLSPIQPKSMPSNASMFVEDCEDPYWANGKDFDMVHLRGMVGFLLDLDTMVVNVHEHLKEGGWIEFQDFDYTVRCDDGTMQKDDPLRVFFDTCAQGIRKYGCTNFGKKDVRKSLIAAGFTRVQAVSEKVPISCWPQDEGTKDLGKLMEANIMDLIGSMSVKPLNALGIPEEKRKEMVSQAYKSLGNDKAHRYMNCRIIYGQKNGDQGSVASLGFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DTI5</accession>
    <name>X0DTI5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">pH-response transcription factor pacC/RIM101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_02716</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the pacC/RIM101 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DTI5"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000504">
        <property type="entry name" value="C2H2 transcription factor swi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000340">
        <property type="entry name" value="zinc finger protein 473 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="482"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="512"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="96"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="184"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="576"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="684"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="96"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="603"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="691"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK97557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="806" mass="89079" checksum="37271C6C85FC63B3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0E042</accession>
    <name>X0E042_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E042"/>
    <dbReference type="HOGENOM" id="CLU_181953_1_1_1"/>
    <dbReference type="OrthoDB" id="531564at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044980">
        <property type="entry name" value="NDUFB2_plant/fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6593" checksum="31E35F8664185E0F" modified="2014-05-14" version="1">MAGHGHHSFNGPPKPPVAHVPRIYRFTATALGAGMWFFLMYRAKKDGAVLLGLKHPWDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1Q5</accession>
    <name>X0B1Q5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zygote-specific protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979618">
        <property type="protein sequence ID" value="EXK76060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1Q5"/>
    <dbReference type="HOGENOM" id="CLU_166294_1_0_1"/>
    <dbReference type="OrthoDB" id="10063670at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37475">
        <property type="entry name" value="ZYGOTE-SPECIFIC CLASS V COPY B GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37475:SF1">
        <property type="entry name" value="ZYGOTE-SPECIFIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936104" description="Zygote-specific protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="7874" checksum="DEBF46136D052242" modified="2014-05-14" version="1">MKLLSVVTTLAILSTTVSTGPVAYGICQAGCAGVVMACYGAAGYTWGATVGATAPATIIACNSAFGTCSAACAKVALLAPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B533</accession>
    <name>X0B533_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979406">
        <property type="protein sequence ID" value="EXK77200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B533"/>
    <dbReference type="HOGENOM" id="CLU_164178_0_0_1"/>
    <dbReference type="OrthoDB" id="5104950at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="13709" checksum="AC2A1833484EB8FF" modified="2014-05-14" version="1">MRAITGRGLNEHQFRALRELWVDGIWQSEGPADMDRTDNQDGRQSMKSDESDDDEEDEGEDESECEESDEQDKSEYDSQSSVAIEAGGLSDPESTPASSLVNQEQLFQASAADILLHPEMLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6A6</accession>
    <name>X0B6A6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658587">
        <property type="protein sequence ID" value="EXK77655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6A6"/>
    <dbReference type="HOGENOM" id="CLU_1012076_0_0_1"/>
    <dbReference type="OrthoDB" id="5057964at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="275" mass="28984" checksum="F59D2EFA451C97F3" modified="2014-05-14" version="1">MLKRLKACFSLAAHITLAIVLIAVGTTFLNDSKNEKEGIFKVELGRNLLHRGLSIPTENIPSQATQVVKGADGVAKQATVAVAQATHVVQDIQSKVTSAITAGETLLNKFVPEALAVGTTTGCVEYGDGHSDCVSFPLGDDKTFNIISNLSNEAGSLVNQLHRLPSLKSLFIAGLVCFAISCAYAVVNAVVMILPIASNGLPLKSLICIILSICTCGIFTCFMTLVIIIWFSGRGLAELPKASFHSGPAFWVSIVALVSSASHLVCVVLEKFLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0B834</accession>
    <name>X0B834_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_17043</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JH658530">
        <property type="protein sequence ID" value="EXK78285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B834"/>
    <dbReference type="HOGENOM" id="CLU_014819_3_2_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF13">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK78285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="519" mass="55527" checksum="8DFE257CE76B5FF1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8P2</accession>
    <name>X0B8P2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_16794</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979357">
        <property type="protein sequence ID" value="EXK78525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8P2"/>
    <dbReference type="eggNOG" id="KOG2171">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003794_1_1_1"/>
    <dbReference type="OrthoDB" id="7862313at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="8">
        <location>
            <begin position="386"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK78525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1098" mass="120628" checksum="944E9861E65C0995" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8Q9</accession>
    <name>X0B8Q9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_16785</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979356">
        <property type="protein sequence ID" value="EXK78545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_261687_0_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF1">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE EPSILON SUBUNIT HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935577" evidence="3">
        <location>
            <begin position="20"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1239"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1267"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="185"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="841"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="981"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="845"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1017"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK78545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1298" mass="148076" checksum="44D851EAFA5010BE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BA10</accession>
    <name>X0BA10_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979354">
        <property type="protein sequence ID" value="EXK78606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BA10"/>
    <dbReference type="eggNOG" id="ENOG502RAED">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1686739_0_0_1"/>
    <dbReference type="OrthoDB" id="5066017at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="154" mass="17168" checksum="22A9904EB4175813" modified="2014-05-14" version="1">MSDRTQLPSNEETSPSHAQLFIAVSPPLDFKPKIDFQVPSRWMFAALNPITTTWLTAQGRQNEARYALVKYDGPPAHSKFFEVASIPISELGDVEARVRSVLPEENPQGEAAFNRQYVRDILKNLVDGGILGEDRARDALLAVETFTKLQLKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAA4</accession>
    <name>X0BAA4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658510">
        <property type="protein sequence ID" value="EXK78675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658510">
        <property type="protein sequence ID" value="EXK78676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658510">
        <property type="protein sequence ID" value="EXK78677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAA4"/>
    <dbReference type="HOGENOM" id="CLU_197719_0_0_1"/>
    <dbReference type="OrthoDB" id="3889179at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="78" mass="8662" checksum="24E6CF027F019A8B" modified="2014-05-14" version="1">MQTASSPSDETTNGEFVSIDKRIFKPSKQDRLMSWQAGSGRINIGGTFRSAATGQENIMLPKETYLAVEGTIFKLEYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBG7</accession>
    <name>X0BBG7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9 11">Alpha-glucuronidase</fullName>
            <ecNumber evidence="2 9 11">3.2.1.139</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">aguA</name>
        <name evidence="15" type="ORF">FOQG_19407</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases 4-O-methylglucuronic acid from xylan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9 11">
            <text>an alpha-D-glucuronoside + H2O = D-glucuronate + an alcohol</text>
            <dbReference type="Rhea" id="RHEA:20005"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:58720"/>
            <dbReference type="ChEBI" id="CHEBI:58899"/>
            <dbReference type="EC" id="3.2.1.139"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9 11">Belongs to the glycosyl hydrolase 67 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.139" evidence="2 9 11"/>
    <dbReference type="EMBL" id="KI979783">
        <property type="protein sequence ID" value="EXK75829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBG7"/>
    <dbReference type="HOGENOM" id="CLU_007125_2_0_1"/>
    <dbReference type="OrthoDB" id="6501611at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046559">
        <property type="term" value="F:alpha-glucuronidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02795">
        <property type="entry name" value="CBM6-CBM35-CBM36_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1330.10">
        <property type="entry name" value="Alpha-glucuronidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037054">
        <property type="entry name" value="A-glucoronidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011395">
        <property type="entry name" value="Glyco_hydro_67_aGlcAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005154">
        <property type="entry name" value="Glyco_hydro_67_aGlcAse_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011099">
        <property type="entry name" value="Glyco_hydro_67_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011100">
        <property type="entry name" value="Glyco_hydro_67_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39207">
        <property type="entry name" value="ALPHA-GLUCURONIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39207:SF1">
        <property type="entry name" value="ALPHA-GLUCURONIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07477">
        <property type="entry name" value="Glyco_hydro_67C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07488">
        <property type="entry name" value="Glyco_hydro_67M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03648">
        <property type="entry name" value="Glyco_hydro_67N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029900">
        <property type="entry name" value="Alpha-glucuronds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 11" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="Alpha glucuronidase N-terminal" evidence="12">
        <location>
            <begin position="10"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 67 catalytic" evidence="14">
        <location>
            <begin position="143"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 67 C-terminal" evidence="13">
        <location>
            <begin position="464"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR029900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR029900-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK75829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="834" mass="92557" checksum="2C7EDEFF06CFCB84" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBU5</accession>
    <name>X0BBU5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_19254</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979667">
        <property type="protein sequence ID" value="EXK75984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBU5"/>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="OrthoDB" id="6509908at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="50"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK75984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="443" mass="47407" checksum="DD82CBD1E7C77FEA" modified="2014-05-14" version="1">MSVIDLNFSNAPEVASPRETETKPPMSDSQSSEELETPAPLPPPSNGGIVAWSQVVGAFFLFFSSWGVVNTFGAFQTYYKRTLIPSYSSSSISWIGSVQGFLLFLFGGVTGPIFDKGYLHTLILIGMFAVSFGLMMTSLATEYYQLFLAQGICVGIGCACLFVPSIAIVSTYFTTKRAIATGITASGGSIGSVIFPILFRKLVDRVGFGWTTRVIGFIVVGVLLVSLSVMRTRLPPPKHARSLFDASAFKERPFIVLSAGLFLAFAGLYFPFFYLPTYLSVGLDANKNLSSYSLAILNAASVFGRITPGLVADRIGSLNTLIPMAVLASVFVAAWIGIKNVAGTIVFAVLFGFVSGAIVSLPPTVVARMTPDVSLVGTRMGMCFTFAGLGLLIGNPIAGSLLNLEKKLFWHAQLFSAVMLGAGAVCFIYLWLLLRKPGAGWKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC07</accession>
    <name>X0BC07_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979528">
        <property type="protein sequence ID" value="EXK76358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC07"/>
    <dbReference type="HOGENOM" id="CLU_338898_0_0_1"/>
    <dbReference type="OrthoDB" id="5084805at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="761"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="547"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="774"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="790"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="839" mass="96798" checksum="C367CC56DC0E59A8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCV0</accession>
    <name>X0BCV0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979546">
        <property type="protein sequence ID" value="EXK76304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCV0"/>
    <dbReference type="eggNOG" id="ENOG502R1AU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005513_3_2_1"/>
    <dbReference type="OrthoDB" id="5584477at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="1">
        <location>
            <begin position="127"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="606" mass="68642" checksum="9B95146DF13B9186" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEG9</accession>
    <name>X0BEG9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658670">
        <property type="protein sequence ID" value="EXK76884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEG9"/>
    <dbReference type="HOGENOM" id="CLU_141140_1_0_1"/>
    <dbReference type="OrthoDB" id="5104281at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="89" mass="10071" checksum="21E1D68BEA3F883B" modified="2014-05-14" version="1">MEEEVGRLRRGKKRKATPNPNEKFMTLADALVSCETISEPNQAIQEARAVEDVIEVEGMEEEESSNSEAEELLAVRTHTGHEDKTPRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEI3</accession>
    <name>X0BEI3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979433">
        <property type="protein sequence ID" value="EXK76899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEI3"/>
    <dbReference type="HOGENOM" id="CLU_168414_1_0_1"/>
    <dbReference type="OrthoDB" id="8115477at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936874" description="Hydrophobin" evidence="1">
        <location>
            <begin position="19"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="9531" checksum="44A3980202FC95CA" modified="2014-05-14" version="1">MKTTALLSALTMAAVAIAAPAEIEARGGGGGGGGGGGGGGGGSGGTCNSNNHQQVCCNGGGLLGLACTVGILSTGCNQGTYCCESGSAFGGLVNIHALNCVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF63</accession>
    <name>X0BF63_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658600">
        <property type="protein sequence ID" value="EXK77483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF63"/>
    <dbReference type="HOGENOM" id="CLU_073365_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="26530" checksum="B58AB38DE7FBFF71" modified="2014-05-14" version="1">MENNSPLGADYVHQPHTWEDWWSANHSIPLGTPGDGSRMTNCAYTHANPLYESSVYNYDANSMNPTLDSTYSWNGFDFTTEYASPLLTPTHIVTKELPAPQAHSYLPLAAEYPNQQQNHDPEDLSICKPARRRYFIHENLNPGPKNKRQSTPCRTRSDSSSGSHSTQQSSDRVKKVQEQNRIRASKSRIQQREEVSSLMSRTQELARIRRELSTCVTDLSLEEAPKSRLHNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFI0</accession>
    <name>X0BFI0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658441">
        <property type="protein sequence ID" value="EXK80571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFI0"/>
    <dbReference type="HOGENOM" id="CLU_013866_3_0_1"/>
    <dbReference type="OrthoDB" id="2991872at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF13">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="512" mass="56605" checksum="42BB18B179799591" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIA7</accession>
    <name>X0BIA7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658425">
        <property type="protein sequence ID" value="EXK81576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIA7"/>
    <dbReference type="eggNOG" id="ENOG502S94E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039068_3_0_1"/>
    <dbReference type="OrthoDB" id="61390at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="38312" checksum="27BF7EE37F505B18" modified="2014-05-14" version="1">MFFDQDSFGLGFAAGLITALAIAGIIALVVMRMSDIYGLGHWKLNITTRPPSMWMNVGYWKTHTGEPIDTLPAAASALLEQVVSAAGLSGDAPGKASPRGSLAILDLGFGCGDQTWQLARTATEQGWRDFRYVGLTLNDAQVQTSRRRIYRELSEAGTAFDAEAFSLFRADAAKPQTWSPQIKEAVYSLADEKYTERWLLALDCIYHFSPSRKPVLSHAAKELDANYMAFDLLLNEKASTKDIWRARLIGKMMGCPLKTFLSETEYRDQLVECGYDRNEITIKEITDDVFSGLVKFLDRQDKLLAEYGITMGGFKLAGRLFNWFDKSRVVRAVVVVARTKSKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJR5</accession>
    <name>X0BJR5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_13267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJR5"/>
    <dbReference type="eggNOG" id="ENOG502RXAX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_1_1_1"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051704">
        <property type="entry name" value="FAD_aromatic-hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865:SF7">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865">
        <property type="entry name" value="OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="4"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK82400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="425" mass="46289" checksum="46045E552EA274FA" modified="2014-05-14" version="1">MSTLKVLVVGGGIAGPSVAHWLSRTGAEITLIERSPKARTTGQQLDLRHQGVAVMKKMGIEPAIRAKHVHEVGTQLIDTNGRTKAFFPTIESGTGNQSVTTEYEIMRGDLVNILLGLTEGKKNVKHRFGTSVASLTQDDESDPNGKVHVGFDDGQKDDFDLVVAADGTGSRTRQLMLGPDAPDPRHFLGGYIGFFSALSKPHDTNRFTFCHLPGSRWLGTRKDNPEMTRVYMNIQSQNEGLAAAHKSGKLDDLKAAWADVFADGKWESGRFMDALKNSPDADDLYSTPCQEVRLPPGSWSKGRVVTLGDAAHAQTANGFGTTWGIVGSYILAGEVATLYSQDPSKGVVQGVKRYEEVFRPIATSLQGDQSAFARMVFAPKTQFGVQILHTLARMASWFKLDQGMGLDSKIANWQLPEYPVLNADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKB4</accession>
    <name>X0BKB4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658416">
        <property type="protein sequence ID" value="EXK82271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKB4"/>
    <dbReference type="HOGENOM" id="CLU_933959_0_0_1"/>
    <dbReference type="OrthoDB" id="21416at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="357" mass="39403" checksum="9E478CC0B3B59C07" modified="2014-05-14" version="1">MVHETPARYRVRNGTINLVEEHINMDLFCCRYLSSRPFTTGKSQSISADIHSGYFGFLNYAAAHYIVHIREVETSEVSTYSASRLEAVKAAVVGLAKANCKAISLQAEQSDKANKDLNLAIQGNVLTVRALIGLQQEKSETAIFDATEGPKRHKCHKIQCSKFATGCSNETAPKEQLAVHERPFRCPHTDCFAHAVGYASSKRLENHNEAFHHTTSKAKAKAVFPAELETGEWNLYEACKAGNLDEVKSFNREGADLNSTHPEAVSPFCAAVEAGPGHVCRYFIDNGVDPFRQVCNKMASRTAVASAIYREHLEILEFFLHSGSSPDDSDLVENITYAVHSNRSAALNMLLTARQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLF5</accession>
    <name>X0BLF5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658463">
        <property type="protein sequence ID" value="EXK79708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLF5"/>
    <dbReference type="HOGENOM" id="CLU_2133608_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="113" mass="12634" checksum="7B2CD34B9ED39E57" modified="2014-05-14" version="1">MHYRPLLHETAESTFAFASILHGPHTRQKLSPCASHFLGVASTIPTRLLCSLAFFLSSLKPKEPQTTLTVPSLRFRYGKLHIGSCCVTSWPRRGQLGSLDSPSRTMPTRRLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMB7</accession>
    <name>X0BMB7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658407">
        <property type="protein sequence ID" value="EXK82996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMB7"/>
    <dbReference type="eggNOG" id="ENOG502SV71">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014150_0_0_1"/>
    <dbReference type="OrthoDB" id="4850028at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937028" evidence="2">
        <location>
            <begin position="22"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="814"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="824"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="870" mass="89738" checksum="5DA3BADBDA5B0EBB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMW1</accession>
    <name>X0BMW1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMW1"/>
    <dbReference type="eggNOG" id="KOG1212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_9_2_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF3">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="6">
        <location>
            <begin position="89"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="3">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="242"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK83535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="561" mass="61256" checksum="8405545B824460FF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNE6</accession>
    <name>X0BNE6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protoporphyrinogen oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNE6"/>
    <dbReference type="eggNOG" id="KOG1611">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_1_1"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="27804" checksum="0FA4AF56CCD063A1" modified="2014-05-14" version="1">MSNTAGTPATWVVVGASRGIGLEYVKQLLQAGNTVIAVARNPDASGLSAVIKAHGSPGNCIVEQCDVASSESIDNFAARMRALVRKGIRLDNIVMNAGVLRYPNRATELSYDNFKFHMETNAIGPIICAQKLVNLNPDSPPSKLIFISSDSGSTANFLAYEDGFAAYAASKAALNQMLRHMAQELKRRGGRWAEMCVLALHPGEVHTDMNSGEVGTWDVGTLLEPDESVSGMLKVISEKDHNDSGTFWCWDGRAYPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNT4</accession>
    <name>X0BNT4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14923</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658441">
        <property type="protein sequence ID" value="EXK80568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNT4"/>
    <dbReference type="eggNOG" id="ENOG502RNQ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1777608_0_0_1"/>
    <dbReference type="OrthoDB" id="4994015at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="146" mass="17171" checksum="5F4DEDAB09B0F315" modified="2014-05-14" version="1">MTTFDAETFAFLSSIKKPALDDGATRTRLLNMMENLEAPHPYGILQWLQMAEFRAFAFDNLRVDCVKTWAGYKTQVHPLWIFLLLGRFIATMLGQEKFECTVGGNRYQCPRPEEEKMELEYRYDEWAYETDDVSIDRPYEYGDLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQH3</accession>
    <name>X0BQH3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14836</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658438">
        <property type="protein sequence ID" value="EXK80704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQH3"/>
    <dbReference type="HOGENOM" id="CLU_032655_0_0_1"/>
    <dbReference type="OrthoDB" id="4981596at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF20">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="76"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK80704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="587" mass="66278" checksum="0EAFEE0300AA1862" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR15</accession>
    <name>X0BR15_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR15"/>
    <dbReference type="HOGENOM" id="CLU_125078_1_0_1"/>
    <dbReference type="OrthoDB" id="4934395at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="110" mass="11442" checksum="A2C1A844BFE308BE" modified="2014-05-14" version="1">MAVPRASVNLLRCGIRPVTRAAPVLQVRQQSGVSSDGDIGGPGSQQTPPPNPGFRETLNRNWRSIAGAGLLVVAALSYMSSSKGRRAPSDADLKAASSTEIGMSPSQKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR58</accession>
    <name>X0BR58_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR58"/>
    <dbReference type="eggNOG" id="ENOG502RQ7N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025462_0_2_1"/>
    <dbReference type="OrthoDB" id="497541at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021848">
        <property type="entry name" value="HODM_asu-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11927">
        <property type="entry name" value="HODM_asu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="387" mass="44826" checksum="5B5E430EB5CAEF4B" modified="2014-05-14" version="1">MSSLLESMGLRQEVILVAFAAVGLCLFAVYEWMRKGKPAVKTDIEWKTPSPKPLVDFDLDAKKPELYRPCRHGPNHVTMGIRKLDWNNWIEMDSNFLWYHDLKVSELEKDIDAHVQYVDNAVTRDACFEVLQELTAYLTARYPKIFQLSNGILRNTLTKEEFSYPANTPKEAMATAAKLVQDDLVIMVEEDDGQYHLDAGAVCLPGFWRLSEKFRMSLDTLHIEAKVPHYQTKLQKSMNRFFKTMQPDKAVIRNNFFIQLDDGLHWSHRMGDQDSNEVASWETANDKGLTINDLYFRSERQSLRRLPRSKALLFTVRTYFEPITTIAQEPHVPGRLAEAIENWDEAASKYKGKHHWADILLPYLHEQDELQKKSGVLEKIPEGSFPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRX4</accession>
    <name>X0BRX4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658424">
        <property type="protein sequence ID" value="EXK81658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRX4"/>
    <dbReference type="HOGENOM" id="CLU_079105_0_0_1"/>
    <dbReference type="OrthoDB" id="3485856at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="225" mass="25097" checksum="7C5A561E2B9685B7" modified="2014-05-14" version="1">MIETALPSPSECPEDEHKGDGAEAQAPKKIWSRQPDLQIGERNTQFPGCVVEVACSQSSADLEPLAYDYFSNTSFGVQLFIFVNIKENARISVLRGNAGVVTWGMQQVEFQTADKHPANINLALELNVKDFVLSTEVGQYPDLAIRIPFQELHEMLRQALRDSLVKKGRGGNIRRPNKFDGEMVLPANFRTKKDPVAKGDGQFNGNQTTDEVTERQGAYGFRPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS02</accession>
    <name>X0BS02_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fumarylacetoacetase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979335">
        <property type="protein sequence ID" value="EXK81249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS02"/>
    <dbReference type="eggNOG" id="KOG1535">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_2_1_1"/>
    <dbReference type="OrthoDB" id="411064at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000002">
        <property type="entry name" value="2-hydroxyhepta-2,4-diene-1,7-dioate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="80"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="292" mass="31444" checksum="B4020910B2992361" modified="2014-05-14" version="1">MSSNLFKRLVRFAPRSNTSGILIGQPVKDDIDVGLALRNDTEVQVDVFSGTSVLNPGQSTGKVEIIHKIFSPLAANEVGTIRCIGLNYKRHADEVSMELPPIPTMFMKPSTALGDPWPTPTLIPKISQKDGTSDFESELAVILGKTAKNVSEAEAMEYVLGYSACNDVSSRESQLAQSQWSFSKGFDGACPIGPTLVSKDLVPDPTKFKIRGSKNGKVMQESELDDLIFGIPQLIAFLSQGTTLPAGTIIITGTPAGVGMGRTPKERLDAGDEFHVEILPHIGTLVSIFQNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS10</accession>
    <name>X0BS10_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">26S proteasome regulatory subunit N7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_10940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS10"/>
    <dbReference type="eggNOG" id="KOG0130">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_18_0_1"/>
    <dbReference type="OrthoDB" id="15688at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12324">
        <property type="entry name" value="RRM_RBM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008111">
        <property type="entry name" value="RNA-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033744">
        <property type="entry name" value="RRM_RBM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45894">
        <property type="entry name" value="RNA-BINDING PROTEIN 8A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01738">
        <property type="entry name" value="RNABINDINGM8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="40"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="117"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK84980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="153" mass="16946" checksum="8FAB45B43BB27A4D" modified="2014-05-14" version="1">MADVEMDVDVEAGSPPPPARNESDMQTHTKATAVRSIEGWIIVVTNVHEEADEEALQDLFGEYGEIKNMHLNLDRRSGYVKGYALIEYTTLEEARAAIDGAHNQKLLDQTISVDFAFVRPPPGKPGRGRGAGGRNRGRSRSRSPEGKDREERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSG0</accession>
    <name>X0BSG0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Branched-chain-amino-acid aminotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_10770</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSG0"/>
    <dbReference type="eggNOG" id="KOG0975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031922_0_0_1"/>
    <dbReference type="OrthoDB" id="1732691at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF69">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK85110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="42726" checksum="56A34F632CB62B0E" modified="2014-05-14" version="1">MTTGHLGAQLDASKLELTHAPTSKPVPDPDSPEVATLKDGTDRMIVVSWTSQQGWEAPRVVPYGPVSLMPTASALQYATQCFEGMKVFRGYDGRLRLFRPLYNCERLRNSASRIALPSFDPKELLKLIHRLCALESPKWLPKDKPGAALYIRPTLIGSDPSLGFKAPEEVQLYIFMIYWPSPKTTGLQGTRLLASSESVVRAWPGGTGAAKVGGNYAAALVEHVQAKARGFDQVLWLYGPDRQITEAGAANIFIIWKTTSGSLQMVTSPLDENNLILAGNTRRSIIELSQAMFDSEDAEDGLRCEVLERKITMIEVEEAAHEDRLLSIFSVGTAYWIQEIAEINIDGRIINIGLGKRPHVALLRNRMSDIMFGTQESEWADVVLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSR4</accession>
    <name>X0BSR4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Indoleamine 2,3-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_10890</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSR4"/>
    <dbReference type="eggNOG" id="ENOG502RZ6X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010089_0_1_1"/>
    <dbReference type="OrthoDB" id="540174at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033754">
        <property type="term" value="F:indoleamine 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657:SF10">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00876">
        <property type="entry name" value="IDO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="379"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="413"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="4">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600898-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK84926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="425" mass="47600" checksum="EC51650836D228BB" modified="2014-05-14" version="1">MSPHAVTYQLPRIKLTAELKEFAVTSNAFLPEHSPLKQLPDSYYEPWELVVQHLPALIKYFDIRRAVDTLPVLSTERLRSEAEWRRAYSILAFLTHAYVWGGEKPAQILPPQITVPFLAVSKHLELPPVLSYAAANLWNFSSSSNDFTDLDHLDTLHTFTGTESEKWFLLISVAMEARAGTIIPKMMEALEAVKTRDYDVIISALEQLKSCIDSVGVLLERMYEKCDPMTFYYKIRPFLAGSKNMEAAGLPKGVFYDEGDGRGEWRHLRGGSNGQSSLIQFFDVVLGVEHITSGNNTEKAGERSYHDIVKDYMPGPHRRFLTHVARKGSIRELASQTPSSPAQERLQAAFTAATEALTVFRNKHIQIVTRYIILPARSGRKDGPQNLASSSSKKNGEELTGTGGTTLVPFLKQSRDETSEAGRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTT1</accession>
    <name>X0BTT1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose 1-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTT1"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029940_1_4_1"/>
    <dbReference type="OrthoDB" id="3162524at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF2">
        <property type="entry name" value="HYPOTHETICAL POLYSACCHARIDE DEACETYLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="337"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="631" mass="68825" checksum="DC7E78B7A0436F79" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV11</accession>
    <name>X0BV11_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxisomal short-chain alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658415">
        <property type="protein sequence ID" value="EXK82344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV11"/>
    <dbReference type="eggNOG" id="KOG1611">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_8_2_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="33494" checksum="1075B7A2E17EF1C6" modified="2014-05-14" version="1">MSLPILNQYHKKPYQAIDPALPALQQTGRTVIVTGGNSGIGYAIARGFVKANAARVIILGRRKDVVTSAAAKLQEEGRQFGSGTDVQGRTCDISDLASTENLWKALESEGISVDVLVLSAASYGATETILDGGLSKVWGDFESNVRSTLDMTGRFYKQKTTDSGQTKFLVNISSCAAYMWSTMGPDRPTYGLTKNASTLLLQQIAQDTRPTDMQIVSFHPGGVLTDSAKRVGGDNLKGLVFDDENLPGHFSVWAATPEARFLHGRFVWANWDVDELKTGPVREQIDTDEHFLKVGVEGLSEKMGGMVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV13</accession>
    <name>X0BV13_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Choline transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12871</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV13"/>
    <dbReference type="OrthoDB" id="4476201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF14">
        <property type="entry name" value="GABA PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="57283" checksum="ABBEBC4D554F42D5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVB6</accession>
    <name>X0BVB6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6603 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502R9QD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001050_1_0_1"/>
    <dbReference type="OrthoDB" id="5352492at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052159">
        <property type="entry name" value="Competence_DNA_uptake"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046538">
        <property type="entry name" value="DUF6603"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30619">
        <property type="entry name" value="DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30619:SF1">
        <property type="entry name" value="RECOMBINATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20248">
        <property type="entry name" value="DUF6603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6603" evidence="1">
        <location>
            <begin position="1496"/>
            <end position="2006"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="2202" mass="241906" checksum="9EA1D5B170907C78" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW45</accession>
    <name>X0BW45_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW45"/>
    <dbReference type="HOGENOM" id="CLU_126107_0_0_1"/>
    <dbReference type="OrthoDB" id="5036533at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="184" mass="21133" checksum="A3BF7BAC20EA5A70" modified="2014-05-14" version="1">MLSDDRTDNDLYSLYNLGHILAVIRDLPNHIACMDLMRLALRIARAEYTRAVASYEAEDIQMEIAMAKGETFIRSFLSLSDEPKTAFFWCDGCRADITFASEIWTCLSESGSIQLDDKYYKKLKEGIQGPVCSKEHEHYWVPKRNMEEIDAVPVGSVELGEEVISFEAWKEKIREQYVRSCIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWE8</accession>
    <name>X0BWE8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658404">
        <property type="protein sequence ID" value="EXK83238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWE8"/>
    <dbReference type="eggNOG" id="ENOG502T38K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1023234_0_0_1"/>
    <dbReference type="OrthoDB" id="5135153at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="272" mass="29853" checksum="5DBDC909B98E6134" modified="2014-05-14" version="1">MASSSPEAKPDRAAREAEYQALWQVCDRATRKHEYIYADDRLKRSLLEDACDSIMLKRQKVGKAPCGTDISAMVSLHLQREVTGRLLATARMGVPTPSPNPMPYMSSGPAFNAPQDAYPANPSTFNGNPGPYNGNAAAYNVTQAPLHAIPQPQARVSPPDFDFSIPNSTEELREDMDKVINTLREYARRIAALENKLDKFTQERDMWKAGTIGMTNADMSKAASVPPGMFHCPIEGIEGLSAVAYSHPRPLTPRSQTQGRDEEGEGTYQPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXS6</accession>
    <name>X0BXS6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09368</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXS6"/>
    <dbReference type="eggNOG" id="ENOG502RHJM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038732_9_0_1"/>
    <dbReference type="OrthoDB" id="2349068at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF34">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="364" mass="38955" checksum="8D2BBF52351E95B9" modified="2014-05-14" version="1">MSTAHAIAKASKARFLSQFPWTISPFIIGAPMRVMSGPHLALAVSKAGGLGFIGPGAKPEDTSKDLDTVRELLRSSPPQTLPSAFPSKDTLPVGVGFQLWNGDLKSAVNAVQEHRPCAAWLFAPRRGQEELDEWTSQIRKAHPEIQVWIQIGTVQESIEAANSAHRPDALIVQGAEAGGHGRATDGLGIMTLFPEIADQVRESGMSLFAAGGIADGRGVAAALSLGATGIVMGTRFLAATETRISKGYQQEIIRAKDGAQCTTRTMLYNHLRGTIGWPEQYSPRGIINQSFHDHQAGVEFEELKKRHDEALKSGDKGWGPEGRLATYAGAAVGLIHDVRDAENIVKGVQGEAKVVIAELANDTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BY54</accession>
    <name>X0BY54_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12306</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BY54"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_6_1"/>
    <dbReference type="OrthoDB" id="2585655at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF160">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938957" description="Major facilitator superfamily (MFS) profile domain-containing protein" evidence="7">
        <location>
            <begin position="17"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK83444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="483" mass="52733" checksum="FAF9F87F0B19573A" modified="2014-05-14" version="1">MMGNLSFFVMMGQVLGASIPPMLLPLVKDMHVSSTKISQLASWGTLCIGLGNVWALPTVAYIGSRYTILIGLAVFTAGFFWQARAQSYESLLAARVIGGLGGGVVEALGPVVVVLLFPREYVARAMSVYTWALGAGAVFGPMITGYAVDNLGSWRYPNYIFGGICALNLLVMILMFPEPLTNIRVPGDPEPSDISIESIDEEQVGEPKEPLEEVGNAQQYETRPASVATFEPCNLGALWFRRSFFLTLRHNHPPPNFFYLVVEPFRILVSPAVIITVLLFGFSIAGTIATSILASITFSQPPWLWTSGQVGLYNIAPLLGLLAGMPFGGAGADWLAERHLRRNGEFKPESALPILLPFAIATPIATTLIGVGFQRGWHWAVVGLFWAILNANLTGGCNVMISYCTESYPKKAIQIGVVVNVIKNVIGFGVSYSTLDWWMKDKYFMFLTVALVIFVLFVAAVPLWISGPSITRKTKTWAGYEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYT6</accession>
    <name>X0BYT6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979923">
        <property type="protein sequence ID" value="EXK75687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYT6"/>
    <dbReference type="HOGENOM" id="CLU_3092935_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="52" mass="6131" checksum="80A067033D314709" modified="2014-05-14" version="1" fragment="single">MVKNQPPYSPDHNPMEYLLDSVQNRTRKRCLVDEDLTQGDLKSYLEMQAYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZX5</accession>
    <name>X0BZX5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979607">
        <property type="protein sequence ID" value="EXK76092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZX5"/>
    <dbReference type="HOGENOM" id="CLU_1855379_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="138" mass="16145" checksum="1908DC8A4D0D555D" modified="2014-05-14" version="1">MATYDTSLGHVQHPLNQMRRFKQHQTEVTPMHNFICVLSRMIPRKVSARRQTCFAKIRVFYWKYRTVTSLCRHFKSAALIDRYFGKQGMLTSRTATVDHGLTKAILAFEMRLRVGTSHRALKSDPLRSMHSRTLKHIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0G8</accession>
    <name>X0C0G8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0G8"/>
    <dbReference type="eggNOG" id="ENOG502R6TJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120571_0_0_1"/>
    <dbReference type="OrthoDB" id="5015552at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="194" mass="22400" checksum="D7040BB03F0ACB00" modified="2014-05-14" version="1">MAYARCIVSHETTLPSTLALQFSHTKYAKLYSMSLNKRIQDTDSCTFIYDQNKAIKMIFTISWTNEGDDFIFQNEPDAKFWERVVRLCRTVLPLQKCIITELEGTVFREMLEISDQDWSETWRAAVLAPMPENTPQNQPHVSTTTVVQEGARIRRSVARFGSRFGIRVRFPRFSRKKKKKGQNEEVANEATPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0S0</accession>
    <name>X0C0S0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658724">
        <property type="protein sequence ID" value="EXK76402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0S0"/>
    <dbReference type="HOGENOM" id="CLU_056399_1_0_1"/>
    <dbReference type="OrthoDB" id="10288519at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="283" mass="31769" checksum="E833C64436A79C1C" modified="2014-05-14" version="1">MPEGLDVCRIDVCRIAATHLPPASVPLGPTSDNSTLGNGDTDTPGKDEIAHANPQEDPITIPDSLDDSPPSPSIEGSAVKDVQSPSAQPISFPRSLNAFLSHEPLNERTGEKRKRPTEGAALLAVKAFQELWPRKNFFNDIKWLSSEQGDAYVFRDSDLLINARVYILADRNICKSLIHTSLYHLKGALQCYVLEKITSLMEVVRVLYGGTRQNDPARILVSAYIGCFYERIRHLEPFEEVYLEEADFRHDLQNWLDLRLAGGGEGFEVFNRQHEQRCRLALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0U2</accession>
    <name>X0C0U2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0U2"/>
    <dbReference type="OrthoDB" id="3210378at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="672"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="841" mass="93767" checksum="443AAD1304131DC8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C115</accession>
    <name>X0C115_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658712">
        <property type="protein sequence ID" value="EXK76487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C115"/>
    <dbReference type="HOGENOM" id="CLU_118674_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="199" mass="23136" checksum="0735D3A62582C3E0" modified="2014-05-14" version="1">MSRHSGSWPLVEWKSNPYALYDRLNTRDVLHETYDKKYLTSYILKMDWIYRSTSKGCFVWALIDSPEEYRVEALRQFKECLRQEYDEAISMIAALQKGNDTSTLEILFQCVAVSEYVRTLPSSAQRCSSCGQATPEGVDIIRRRCQKHIFFTTCYDEYSSKSLKSIYSWCPCFDPIGLGYIGMYETFPVNSLLRLGLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1P7</accession>
    <name>X0C1P7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1P7"/>
    <dbReference type="eggNOG" id="ENOG502SIR3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038297_1_0_1"/>
    <dbReference type="OrthoDB" id="9978720at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12809">
        <property type="entry name" value="Esterase_713_like-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF4">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936128" description="Secreted lipase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="43073" checksum="C8EA2C5F898B0F41" modified="2014-05-14" version="1">MARFVLNSLLFLGGALASPVQERKVDCTGTNAISMHCRSNEVPYTRDFFYIGGRSAKGTSGTITVDQIYVEKLTPTKQWTQKHPLVFFHGGGLSGSTWLNTPDNREGWASYFTKKGYVVYLVDNNAIGRSAENAIASFPMAAGSATETVMKFFTSPENYETYPQAKLHTQWPGTGADGDPVYDQFKKSLIPLTTNFVGQENALRAGGCELLSLLGEKAFLISHSLGSRNPLLLSNDCPEYIAGSINLEAATSPFWSYAEGLGGFAGSPWGLTNTPVTYDPPVSDPSELESESVGEETLAHRNCYLQVEPARKLPQINKVPYLLLTGEASVHITYDHCVIDFLKQAGGKPEWIKLADWGIKGNGHFLHVEKNNMQIAGIVDAWIQKKSFNGTKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1U0</accession>
    <name>X0C1U0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphatidylglycerol lysyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11237</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1U0"/>
    <dbReference type="eggNOG" id="ENOG502S16U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032338_0_1_1"/>
    <dbReference type="OrthoDB" id="5421852at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016755">
        <property type="term" value="F:aminoacyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055091">
        <property type="term" value="P:phospholipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024320">
        <property type="entry name" value="LPG_synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051211">
        <property type="entry name" value="PG_lysyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34697">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL LYSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34697:SF2">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL LYSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09924">
        <property type="entry name" value="LPG_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Phosphatidylglycerol lysyltransferase C-terminal" evidence="6">
        <location>
            <begin position="85"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK84714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="434" mass="48689" checksum="88B4F7613D4422CC" modified="2014-05-14" version="1">MERHDMLYSDVESASSSTYQHSQTDISVVSASTAPSTVVPDEGIISRTYDAAKTLSHIKCPHRLRREHQRNSPNNTAARAAFKHDYQSYAQTSHMGILDPAYKVFVSKKGYGSLIYKLHARTVVVAGDPLCSEFHRKALFSELRRYRWARGLSLAFVGISEEFAKYAQQQGWATMHFGHEAVLNPLTNKVLRKQAGKRTIAQNKQLLDPKRGGISVSFYSPAVNETDPELERQLQDLYDDWREDRNRKHGDGSQAFVTVYNLFSLPESTIFLYTSDRDGKINGLATLRELGAERGYHLDPCIASQDAPRGISDLLIVTAMELLKASDVGYMSLGIEPLDEVQEVTGSSKLVSRLWKDGYNQMIQSVPVTGKAAYFKKFCPDESLTSKLFICIPSKGIPVRRSIALLQFANMSPGQLFTQIHLGDRHKEKHTPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2L0</accession>
    <name>X0C2L0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methylmalonate-semialdehyde dehydrogenase (CoA acylating)</fullName>
            <ecNumber evidence="2">1.2.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_08644</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.27" evidence="2"/>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2L0"/>
    <dbReference type="SMR" id="X0C2L0"/>
    <dbReference type="eggNOG" id="KOG2449">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_10_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000002">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase (Acylating)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000003">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase [acylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866:SF3">
        <property type="entry name" value="METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="83"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK88381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="570" mass="61065" checksum="5BCF785EDF44A452" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C334</accession>
    <name>X0C334_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C334"/>
    <dbReference type="eggNOG" id="ENOG502RXKN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017444_4_1_1"/>
    <dbReference type="OrthoDB" id="1911848at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029498">
        <property type="entry name" value="HeLo_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14479">
        <property type="entry name" value="HeLo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="254"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="564" mass="63556" checksum="25B4F5A93524C488" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C443</accession>
    <name>X0C443_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7702 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C443"/>
    <dbReference type="eggNOG" id="ENOG502SRJ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064985_3_0_1"/>
    <dbReference type="OrthoDB" id="2560628at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056119">
        <property type="entry name" value="DUF7702"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G00100)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109">
        <property type="entry name" value="UNPLACED GENOMIC SCAFFOLD UM_SCAF_CONTIG_1.265, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24800">
        <property type="entry name" value="DUF7702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7702" evidence="2">
        <location>
            <begin position="2"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="264" mass="28623" checksum="E818511E28EFDE74" modified="2014-05-14" version="1">MTDSISVAKLAIYIILLQPALYCLFKHGKTGFIGWLYVQIFCVLRIVTGSIGLHETNSSTGSIILNSIGLSPLLLAASGILHEARRGTNPRLSRKLDIILEIKYHGLVGAAMALIIVSVVGLQNGDSVSTNKTLLKVASALIALAWLLLAIWALWSLGKCQKSSTNNRVSSFRGGKLLLYAVFINLPLLGLRLAYGIAYLQLKISHPTSGFLTSKAVQVCLSVVPEMLITTIFLLVGVMTRNLKHEIKKLDSALPVGDGYEIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4L8</accession>
    <name>X0C4L8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07972</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4L8"/>
    <dbReference type="HOGENOM" id="CLU_3384767_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="33" mass="3895" checksum="9DCE84C20B0F9268" modified="2014-05-14" version="1">MMKCPDIAVHFGGFGRISGDMYRLCRRYSALWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C512</accession>
    <name>X0C512_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SMODS and SLOG-associating 2TM effector domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C512"/>
    <dbReference type="eggNOG" id="ENOG502RJMA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_969934_0_0_1"/>
    <dbReference type="OrthoDB" id="5398270at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041622">
        <property type="entry name" value="SLATT_fungi"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033635">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793">
        <property type="entry name" value="SLATT_FUNGAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793:SF1">
        <property type="entry name" value="SMODS AND SLOG-ASSOCIATING 2TM EFFECTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18142">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="SMODS and SLOG-associating 2TM effector" evidence="3">
        <location>
            <begin position="93"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="294" mass="32256" checksum="F5C11197CDD461F2" modified="2014-05-14" version="1">MAEIDSTVPQTSMDPTQNFGHYMNGADQSSMENGPGQKKHKNVRYRFLSPTEWAILARGVGGIIDIEHNKPVHPTSSLWPPNGLPQGLYRDCVYRRTISSYSFHFIGFVRAILFVLQLMIGASITALSSGGFDDTAITILAASNTVIAGLLALLHNSGIPDRYRYDKSEFQKVEDHIREVLATGIVRADQSVQEALAKCYDRFDHARRTVEANMPSAYAPSQSTPSSRRGSQPQHQPLPPMPMPIPIPARAPTTVASTPTHTRAATEPITPPRKKSLNTEAAQEEKGPTTKPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5E6</accession>
    <name>X0C5E6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10073</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5E6"/>
    <dbReference type="HOGENOM" id="CLU_605565_0_0_1"/>
    <dbReference type="OrthoDB" id="5183255at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="452" mass="50194" checksum="1836DE3065FF1842" modified="2014-05-14" version="1">MPTSIPYDSSLTLMSVVNQDALKSVEAIAELQAPVDAAQDALDEELKKLNVAVEAAAGAYATAKMAAEPQITGIRTSTLFISRLRSRLIICANSATYSAQIASYVSGAVSSVFGAKQLIKIGNTASRQVRRQVISHSIEGTLVLSTINVGAWFAKAEGKVCVDSKFASNMKNLLSQQNIQSYVIVLTMGVILLMVANEVATASMAEASRTTGQASEMRGKYIESSLSALATIDGEENKILDVNSMMTALDDYLKKAADGKAGIFSTSQNIENLQKFFLAERDLNGTDEDITGTLNILCNDFPKPILWDTENTSNSFGTFVIEFTDKDLEFMKEEGFHSKPYIKSRKDTLILEEDKKQMLVLARDFPFIVYSIQYELPADFQSRIFPVEKNEKMKCFVPFFPFRRPFYHRAEAILDDLVFKELYGKAEKESEVVSLRQPLDIRYLRDEILGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5F2</accession>
    <name>X0C5F2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5F2"/>
    <dbReference type="eggNOG" id="ENOG502RE1J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_270856_0_0_1"/>
    <dbReference type="OrthoDB" id="3235083at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="713"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1200" mass="132534" checksum="81D1237BCA9AAD61" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5L9</accession>
    <name>X0C5L9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_17257</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979368">
        <property type="protein sequence ID" value="EXK78047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5L9"/>
    <dbReference type="eggNOG" id="ENOG502T5B7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_10_0_1"/>
    <dbReference type="OrthoDB" id="5273647at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF92">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="25"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="283"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK78047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="366" mass="41496" checksum="E073FC6D6BDE0C77" modified="2014-05-14" version="1">MAIGPSTLLITEWTLIALSTVVIIARIYLRLVIQKRKLIDSDIWMILAWAAGITVASFCVTYVHMGVMEPWVDGTLKDYDGNREDKEFILKLLWICALPFFTAFYLCKAALLAVYRQVIPVHMHKRRMFLWATALYVALSYIVTMVLPFCVCIPVTRFWSLEPDNKCPHNAANMFLKTSWALHFAGDVFIFILPWLIVPDLMIKGWLRVGVYLTFLLGIINMVISIVRFNELFIAGANRKVSIVEAHFWNTLDLYLGLVIACLPSLRPYFNLAANSRAFSSIRGKGTSQGSRYTTDSIQKPEAARLAQDQSGISPSRPVRRSSHSSRDFDLESCADSSDSHEDAKNKAFEIELARVRTRAREASDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6N7</accession>
    <name>X0C6N7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_16931</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658523">
        <property type="protein sequence ID" value="EXK78397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6N7"/>
    <dbReference type="HOGENOM" id="CLU_001265_0_2_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF81">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="63"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK78397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="278" mass="30867" checksum="5B21C43686B645AE" modified="2014-05-14" version="1">MADKTSQLAVAETKLPPLPSKLGREETDSESIAQHGFTTEYLNELVLDREKNKRLVKKVDMVLLPLMAGTYVLQFIDKQALSYSAVFDLLEDTGTTLKQYSWFGSIFYLAYLVAEYPWSFLAQKTLMAKVVAGCIIAWGSIMMITAASTNFAGLAVCRFFLGIFEAPITPVFMMIVGMWYTRQEQPLRAGVFYSCNGIGLMLGGLLSFAIGQVEGFKVWKAIFIICGGITVLFGGLLLWKLPDNILRAKGFSLEEKALLIGRARLAKTGILNRTIKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7D6</accession>
    <name>X0C7D6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7D6"/>
    <dbReference type="eggNOG" id="ENOG502T2TZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006938_0_0_1"/>
    <dbReference type="OrthoDB" id="3497519at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1114"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1217"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1218"/>
            <end position="1256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1256" mass="142803" checksum="D2A7A5C98327AB84" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7K5</accession>
    <name>X0C7K5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endo-chitosanase</fullName>
            <ecNumber evidence="10">3.2.1.132</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_07203</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin. Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endohydrolysis of beta-(1-&gt;4)-linkages between D-glucosamine residues in a partly acetylated chitosan.</text>
            <dbReference type="EC" id="3.2.1.132"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 75 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.132" evidence="10"/>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7K5"/>
    <dbReference type="eggNOG" id="ENOG502S39Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046555_0_0_1"/>
    <dbReference type="OrthoDB" id="4756206at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016977">
        <property type="term" value="F:chitosanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009939">
        <property type="entry name" value="Chitosanase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061">
        <property type="entry name" value="ENDO-CHITOSANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061:SF6">
        <property type="entry name" value="ENDO-CHITOSANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07335">
        <property type="entry name" value="Glyco_hydro_75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152119" description="Endo-chitosanase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK90410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="284" mass="30233" checksum="0D9193409BD69859" modified="2014-05-14" version="1">MGSLRFLLFASIATLVSCRDVPDNIKVFKESIIKQGSCNDTLAEGFHSADGDDGSYVYCGDHLKDYNVIYLQGTKGKLVNMDIDCDGVQGSSADDGRCGSSGDTQSVTSFQDQLKSYGTDQKDLDANIHPYVVFGNVGTKKNWPTFDAQKHGIKPLSVMAVVCGDKMFYGIWGDENGDDGDEAMVGEASISLATACFGDDMNGDNGHDEDDVLYIAFPGSDAVPGEDGADWDAKNFKDFEESLGGVGDKLVARIEDTDSGASCLWPGTWGMGLLVASAMAAMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8W9</accession>
    <name>X0C8W9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8W9"/>
    <dbReference type="HOGENOM" id="CLU_2740092_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="71" mass="8439" checksum="7DE0E2C69D5D3AB6" modified="2014-05-14" version="1">MDAETGLFFGRFAKYRSPTTRATMIWALDLLKNIENVLFLFEQEVFDALCHRYAAKRQWSIKKSNRYAMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0C943</accession>
    <name>X0C943_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Lysophospholipase</fullName>
            <ecNumber evidence="2 10">3.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_09178</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the lysophospholipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="2 10"/>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C943"/>
    <dbReference type="eggNOG" id="KOG1325">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014602_0_0_1"/>
    <dbReference type="OrthoDB" id="4084751at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1090.10:FF:000010">
        <property type="entry name" value="Lysophospholipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002642">
        <property type="entry name" value="LysoPLipase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728">
        <property type="entry name" value="CYTOSOLIC PHOSPHOLIPASE A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728:SF33">
        <property type="entry name" value="LYSOPHOSPHOLIPASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01735">
        <property type="entry name" value="PLA2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00022">
        <property type="entry name" value="PLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51210">
        <property type="entry name" value="PLA2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9 10" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6 9 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152138" description="Lysophospholipase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="PLA2c" evidence="12">
        <location>
            <begin position="61"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="38"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK87364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="648" mass="70259" checksum="4DDA36C6715AA322" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9B9</accession>
    <name>X0C9B9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PI-PLC X domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9B9"/>
    <dbReference type="eggNOG" id="ENOG502RUV2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037358_2_1_1"/>
    <dbReference type="OrthoDB" id="7984201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF146">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012542614" description="PI-PLC X domain-containing protein 1" evidence="1">
        <location>
            <begin position="16"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="32236" checksum="CE244A8AF10AC71D" modified="2014-05-14" version="1">MQLSLILAFATATSAACNGHDELCRRKYSVITFIGTHNSAFVGKLPVHNQYISVAEQLNLGVRFLQAQTQDKDGDIQMCHTHCWELDAGPLQDCLEEISEWVGKNPDEVVTIFLTNIDALPIEKFDEAFSSAGLKDLVFRPKTKLSRDEWPTLQKLLEDRTRLVVFMDYNMDEGRVDYILDEFDYFWETPFGESNSSFPTCEVDRPEKGDPTQLMGIMNHMLNHDVLGIVIPNQADAKKTNSEYSIQKQIDLCEDNWGRRPNVVLLDWVNVGEAMDAQISLNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9P8</accession>
    <name>X0C9P8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MADS-box MEF2 type transcription factor MIG1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_08789</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Transcription factor acting downstream of the MPS1 MAP kinase (MAPK) cascade during conidiation and plant infection. Required for overcoming plant defense responses and the differentiation of secondary infectious hyphae in live plant cells.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Interacts with MAPK MPS1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MEF2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9P8"/>
    <dbReference type="eggNOG" id="KOG0014">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024080_1_0_1"/>
    <dbReference type="OrthoDB" id="1898716at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008301">
        <property type="term" value="F:DNA binding, bending"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00265">
        <property type="entry name" value="MADS_MEF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1810.10:FF:000013">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033896">
        <property type="entry name" value="MEF2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11945">
        <property type="entry name" value="MADS BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11945:SF534">
        <property type="entry name" value="MYOCYTE-SPECIFIC ENHANCER FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="11">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="71"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="374"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="581"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="512"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="587"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="606"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00059910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00065556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK87933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="652" mass="70002" checksum="C8337741402E8982" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CC64</accession>
    <name>X0CC64_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CC64"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="28108" checksum="FB97FC43961A9AC3" modified="2014-05-14" version="1">MLNLTNKVALIIGLGQTGTEGWGIGAACAVTLARQGAIIFGGNRTLASTTKTKETIEAEGGTCDIIATDATDSASVKALVDACMKKHGRIDILLTSVGQSQPGDPASMSEEVWDSQMDINLKSVYLACHHVLPIMESQKSGSVICISSIAGLRYIGKPQVAYNTAKAAILQFVKATAIIYAAKGVRLNAVVPGLMNTPYTRSLAERFGKGYEEFCRAREEQVPMERMGDAWDVASAVAFLAADEARYVTGQKIVVDGGITSSTGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD37</accession>
    <name>X0CD37_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_08017</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD37"/>
    <dbReference type="eggNOG" id="ENOG502RYIG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015534_0_0_1"/>
    <dbReference type="OrthoDB" id="3524154at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057026">
        <property type="entry name" value="Znf-C2H2_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24537">
        <property type="entry name" value="zf-C2H2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="473"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="88"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="165"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="217"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="301"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="371"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="392"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK88714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="620" mass="68454" checksum="E754360BC06AF226" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDM1</accession>
    <name>X0CDM1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658437">
        <property type="protein sequence ID" value="EXK80717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDM1"/>
    <dbReference type="HOGENOM" id="CLU_042688_4_0_1"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="391" mass="43793" checksum="1B150DFAFF8DAA8F" modified="2014-05-14" version="1">MDNTKAFGTLTMHIIHTEPSPDPMDGPYLYVPEAKGVVKRTYPLRSFREQVFPDNSQDTLEVGRAFLRQNGCSAFQHTSKLNLFDVKFSNEARTAYYSEIVELVQHITGCAKVFLISSVTRGGDAEDARTSDKAEEAKKEEDNKRPGKDKANLTEHEEAGRKMASVDNLQPYHLPTTIKPSRIPHMDYTPLGARQLIRSMRSDVHHYADAEAGIIDYENKLCASAGNGISADKENSDEFLFQNYNKPDQPGPRYAIFSIWRPLKLCTQDPLAFVKRSDFDAACGGSDNDLEYWRYNLRTPGFKGDWCWNLAMVRAREGTDEGSGKLMAGPVWNYIPEQRPDEVLFIKHFDSASLGPNGTEVPGVPHASPDLGSAGYGDARESIETRVIAFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEN9</accession>
    <name>X0CEN9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_05151</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEN9"/>
    <dbReference type="SMR" id="X0CEN9"/>
    <dbReference type="eggNOG" id="KOG1749">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115574_0_1_1"/>
    <dbReference type="OrthoDB" id="1713912at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03367">
        <property type="entry name" value="Ribosomal_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000007">
        <property type="entry name" value="40S ribosomal protein S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_uS12_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003254">
        <property type="entry name" value="PRK04211.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK92890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="145" mass="15744" checksum="DC1C34DDF77BD2A7" modified="2014-05-14" version="1">MAGGKPRGLNAARKLRTNRKDQKWADLAYKKRALGTAYKSSPFGGSSHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVGLLALWKEKKEKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CG02</accession>
    <name>X0CG02_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658426">
        <property type="protein sequence ID" value="EXK81557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CG02"/>
    <dbReference type="HOGENOM" id="CLU_014424_0_0_1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00306">
        <property type="entry name" value="Peptidases_S8_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056002">
        <property type="entry name" value="DUF7580"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24476">
        <property type="entry name" value="DUF7580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="DUF7580" evidence="9">
        <location>
            <begin position="183"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="683"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="689"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="726"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="885"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="970" mass="110241" checksum="9B6F78C3793DBC08" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGZ5</accession>
    <name>X0CGZ5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGZ5"/>
    <dbReference type="eggNOG" id="ENOG502SJIB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061836_0_0_1"/>
    <dbReference type="OrthoDB" id="5340195at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="272" mass="30563" checksum="30D1F3E267DBAEE8" modified="2014-05-14" version="1">MTRREFFDHRFRIHGSISDAIVDKDQKPYKYIQTQVFDSAFESRPGGPLNANHNWVGRDDTTELFFRDWDHVQKCFSSDYVKTTIAPDGPFFADFEPSVVLMAYEKTIPLQTAAARKRAEVVTGAMDSGDSTVAMYFISAPDDKKDGESLEPTITPRLVDAIKSCCQDQACGLIGNTGAVSDQFDLNSYFGGANMPRYALVYKIFLTGLESVPLVRKAQAQFEKDTQSIIDLHKSFILFSQEALVMDVKKGVRFSRNRQPVFKDLPGSSHLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CH47</accession>
    <name>X0CH47_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cutinase</fullName>
            <ecNumber evidence="2">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_13686</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cutinase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="2"/>
    <dbReference type="EMBL" id="JH658419">
        <property type="protein sequence ID" value="EXK81927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CH47"/>
    <dbReference type="eggNOG" id="ENOG502S3AW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040058_2_2_1"/>
    <dbReference type="OrthoDB" id="2975078at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050525">
        <property type="term" value="F:cutinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF2">
        <property type="entry name" value="CUTINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00129">
        <property type="entry name" value="CUTINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="8">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="74"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="207"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="245" mass="26238" checksum="108D50834D4CFA2F" modified="2014-05-14" version="1">MSIYGHSSVSSKTHLNVKKYAARIDELFQNITIELFPQSTTPDPNMADTSRLWQQLFSEFTVNSQEDALNQTRCADITVVFARGTNEGGNVGAVAGPPFIDALREKAASLSVAMQGVEYAANVTGFALGGDPNGSLRMAFDIAAVAVKCPKTKITISGFSQGAQLAHNAAKYLPSVILERVSSAVTFGDPLQPSPLKGLEDRSLVICNSGDDICAKGSKVTLPHFAYPGRVYEAADYVLKKAKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHS2</accession>
    <name>X0CHS2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16 17">Ketol-acid reductoisomerase, mitochondrial</fullName>
            <ecNumber evidence="5 17">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15 17">Acetohydroxy-acid reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14 17">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">FOQG_06957</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="17">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17 18">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="5 17"/>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHS2"/>
    <dbReference type="eggNOG" id="ENOG502QQBF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033821_1_2_1"/>
    <dbReference type="OrthoDB" id="10255643at2759"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000003">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000005">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000013">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000167">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016207">
        <property type="entry name" value="KetolA_reductoisomerase_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371:SF1">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000119">
        <property type="entry name" value="Ilv5_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 17 18" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 17 18" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="21" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 17 18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 17 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 17" id="KW-0521">NADP</keyword>
    <keyword evidence="11 17 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="19">
        <location>
            <begin position="65"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="20">
        <location>
            <begin position="256"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00072637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR000119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EXK90813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="405" mass="44924" checksum="9C90688C3AF92F36" modified="2014-05-14" version="1">MASRNFTKALRGPARQLASAPRVQQRTFVAAARSAARVGAVARPVAAGPVQQQVRGVKTIDFAGHKEDVYERADWPQEKLLEYFKNDTLALIGYGSQGHGQGLNLRDNGLNVIVGVRKNGKSWKDAEQDGWVAGKNLFDVDEAISRGTIVMNLLSDAAQSETWPAIKPQLVEGKTLYFSHGFSPVFKDLTKVEVPSNIDVILCAPKGSGRTVRSLFREGRGINSSFAVYQDVTGKAEEKAIALGVAIGSGYLYKTTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGANGMDWMYEACSTTARRGAIDWSPRFKDALKPVFNSLYDAVKDGSETKRSLEYNSQPDYREKYEAEMKEIRDLEIWRAGKAVRSLRPENQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJ51</accession>
    <name>X0CJ51_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_13025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJ51"/>
    <dbReference type="HOGENOM" id="CLU_001265_1_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF230">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="258"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="456" mass="49467" checksum="01B8076E23EDFFE1" modified="2014-05-14" version="1">MERSRSTSPTLFREDAATPDIESAPTSVPPSQIDLSTGQDNEKEPEKKDIESDVGAWLCVFASMLFLISSYGFMNSLGTIQSHLTLNELKGYSVSQVGWISGTYLFLSLIFNFQIGSILDRYGPQILGPIAAAFSTVTFLLLAECTQYWHFILCLGLFGSIGSGIGAVTAIGVIGKLFTRRRGLAMGIAVMGTSLGGIIYPMMLRATFGKLGWAWSMRLVALVIACITSLGVLCYLPFRRLTEGQQTVQKPQRFSLDLSAFKSLSFVVTALGICMVEFVNYGISGLLPTIARGAGFSTEDGYTLLSILGACSCLGRFSIGFVGDKVGPFNAMITTMFVILVFISSIFIPFSTTSASLMYTFTALWGYCSGSFYVLSPLCTGKTCEPQDYARYFGSTNMCVAVALLLANPLSGILLERLGAQLLGCFYLAIIILAAIFFITGRSLLLGKWLVLRRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKM3</accession>
    <name>X0CKM3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKM3"/>
    <dbReference type="HOGENOM" id="CLU_2794035_0_0_1"/>
    <dbReference type="OrthoDB" id="10276141at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="68" mass="7486" checksum="9395E19C4FFEFF3B" modified="2014-05-14" version="1">MAKSKSAPPSSTGWEHATAVTENLPKVPANLESARKRIKLEEGKPSFSADQCIVIDAHIKEERVTRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKN1</accession>
    <name>X0CKN1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKN1"/>
    <dbReference type="HOGENOM" id="CLU_2812470_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="67" mass="7168" checksum="1EAE8B99467042E5" modified="2014-05-14" version="1">MLRFCNIEIILLCIDTKLGDSFSTRANFTFGVNGRPKTDSAGVDPDELLLSLSGVLSLFSASSLKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKY9</accession>
    <name>X0CKY9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="14">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_05964</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 21">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="14"/>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKY9"/>
    <dbReference type="eggNOG" id="KOG0944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009884_1_0_1"/>
    <dbReference type="OrthoDB" id="361536at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02658">
        <property type="entry name" value="Peptidase_C19B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14385">
        <property type="entry name" value="UBA1_spUBP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14386">
        <property type="entry name" value="UBA2_UBP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000086">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000396">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000587">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000235">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000144">
        <property type="entry name" value="Ubiquitinyl hydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016652">
        <property type="entry name" value="Ubiquitinyl_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041432">
        <property type="entry name" value="UBP13_Znf-UBP_var"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF664">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17807">
        <property type="entry name" value="zf-UBP_var"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016308">
        <property type="entry name" value="UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 14" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 14" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="18">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="18">
        <location>
            <begin position="150"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="17">
        <location>
            <begin position="301"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="578"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="640"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="685"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="728"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK91978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="774" mass="85762" checksum="488023C5119FDD78" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMN4</accession>
    <name>X0CMN4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Palmitoyl-protein thioesterase 1</fullName>
            <ecNumber evidence="2">3.1.2.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Palmitoyl-protein hydrolase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_04017</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palmitoyl-protein thioesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.22" evidence="2"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMN4"/>
    <dbReference type="eggNOG" id="KOG2541">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050129_0_1_1"/>
    <dbReference type="OrthoDB" id="10263094at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000107">
        <property type="entry name" value="Palmitoyl-protein thioesterase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002472">
        <property type="entry name" value="Palm_thioest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF8">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02089">
        <property type="entry name" value="Palm_thioest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00414">
        <property type="entry name" value="PPTHIESTRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936503" description="Palmitoyl-protein thioesterase 1" evidence="9">
        <location>
            <begin position="23"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK95446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="333" mass="37702" checksum="35D3FF947EDDE778" modified="2014-05-14" version="1">MSFPSLLRLGLAIGALAGQSYASPFAPIHTRDDLSDTPLPIVVWHGLGDQFNSDGMKSIQALAEDIHPGTFVHIIAIDEDPSQDQMATFRGNVSDQVSKVCEELAKHPILSTAPAIDAIGISQGGQFLRGYVERCNWPQVRSLVTFGSQHNGIIDFRSCGATDWLCKGAMALMRFGTWSKLVQSSLVPAQYYRNPATEADYKKYLENSNFLADINNERELKNEKYKANLSKLTNFVMWMFEDDDLVIPKESSWFEEVNGTEVIPLRARELYHEDWLGLRELDRNGGLRFRSAPGKHLENLYELLNETVTNYCGPWKRTFESDMEDSWDRLELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMW0</accession>
    <name>X0CMW0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_11834</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMW0"/>
    <dbReference type="HOGENOM" id="CLU_011017_2_0_1"/>
    <dbReference type="OrthoDB" id="3862662at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK83877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="673" mass="76879" checksum="6F55D78D06175943" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNN4</accession>
    <name>X0CNN4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chromatin modification-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_03055</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of an histone acetyltransferase complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The PHD-type zinc finger mediates the binding to H3K4me3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ING family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNN4"/>
    <dbReference type="HOGENOM" id="CLU_006204_0_0_1"/>
    <dbReference type="OrthoDB" id="4173905at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF42">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="13">
        <location>
            <begin position="677"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="104"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="259"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="427"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="427"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="462"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="496"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="571"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="593"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="680"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="682"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="693"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="698"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="704"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="707"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="722"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="725"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="679"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="690"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="694"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK95756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="739" mass="78369" checksum="D2DF2FFF07164626" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPU0</accession>
    <name>X0CPU0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_11336</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPU0"/>
    <dbReference type="eggNOG" id="ENOG502RXDV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2158536_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF3">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK84547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="111" mass="12636" checksum="1BE2A4DAEA20EC48" modified="2014-05-14" version="1">MPKTRRERRESPPRPKKTARLTCKNCRARKVRCDGGQPICGICIAYNETCQYDRPPPMTQIRAMADKIAQLEQTIKDLQNKDGTSTAPLQASAAVLAKLRNRSTNRFDRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ02</accession>
    <name>X0CQ02_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ02"/>
    <dbReference type="HOGENOM" id="CLU_3242189_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="43" mass="4837" checksum="A25854F8A2EE3843" modified="2014-05-14" version="1">MHPERVGVTLDDRHYARLRLRLVTGGALIQGDRRQEGSGSHPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQE9</accession>
    <name>X0CQE9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetylxylan esterase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQE9"/>
    <dbReference type="eggNOG" id="ENOG502SQ4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_737791_0_0_1"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF9">
        <property type="entry name" value="CUTINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937844" description="Acetylxylan esterase 2" evidence="3">
        <location>
            <begin position="18"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK96381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="48367" checksum="059C223B3E27EF70" modified="2014-05-14" version="1">MLLILRYLILFVTFVTCQEYGQPGNASCVSGAHIIVARGSLEPRGPGIIGAVAQQVLQRIPHSEMISLEYPAIYNPYQPSQMEGVAALSVVLAQYVTVCPKTKIILLGFSQGAHVIADVMCGASSIGFLPTKPSPSAMNNNIAAVVLMGDPSTTKGQPFHVGSSVGNGIFPRQKPEGCQCVSDKTVSFCDAGDPFCEAGGHDLRTHMNYVTAYGHVAVDYAFYPTNISAMISFMLVLSFLMVLVSANSTTDAITCAKGAHLIVARGSLEPEGPGAMGILAEEIIKLIPGSDMEALVYPALYNEYVESQTEGVRTMNSVINNYVKNCPDTDLILMGYSQGAHVTMDTMCGASSEGFPGTLSQPSYITDNVAAIIAMGDPSLTEGQPFLVGTSEGSGIFPRNLPIGCNSIASKTVSICDKGDPYCEAGGKDLSVHLSYIKNYGEFTVGHVVKAWKSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQM7</accession>
    <name>X0CQM7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11052</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQM7"/>
    <dbReference type="eggNOG" id="ENOG502SH59">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010508_0_0_1"/>
    <dbReference type="OrthoDB" id="3037908at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="618"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="695" mass="77421" checksum="CE0F1E9CA7DAC0FE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRH8</accession>
    <name>X0CRH8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRH8"/>
    <dbReference type="HOGENOM" id="CLU_3260559_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="42" mass="4692" checksum="88639A8DD339E41F" modified="2014-05-14" version="1">MQGLDGEYDPNVIAGQVKTQWLVERERAGDQHQAADPWVLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRP6</accession>
    <name>X0CRP6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_02431</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRP6"/>
    <dbReference type="eggNOG" id="KOG0926">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_0_4_1"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17982">
        <property type="entry name" value="DEXHc_DHX37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000637">
        <property type="entry name" value="ATP-dependent RNA helicase DHX37/DHR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF99">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="393"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="592"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="95"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="658"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="262"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="670"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK97120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1211" mass="135278" checksum="CD36599F83413D03" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVL9</accession>
    <name>X0CVL9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">O-methylsterigmatocystin oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_09799</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVL9"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_3_1"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK86532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="57897" checksum="67F504989EB3B507" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXC2</accession>
    <name>X0CXC2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXC2"/>
    <dbReference type="eggNOG" id="ENOG502S9NK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013057_0_0_1"/>
    <dbReference type="OrthoDB" id="5226662at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081:SF2">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081">
        <property type="entry name" value="ZINC FINGER PROTEIN DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="392"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="507"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="668" mass="76324" checksum="046DBC564A9B1755" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZY3</accession>
    <name>X0CZY3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZY3"/>
    <dbReference type="HOGENOM" id="CLU_027634_3_1_1"/>
    <dbReference type="OrthoDB" id="204058at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004454">
        <property type="term" value="F:ketohexokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01939">
        <property type="entry name" value="Ketohexokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000072">
        <property type="entry name" value="AT09463p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052562">
        <property type="entry name" value="Ketohexokinase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034093">
        <property type="entry name" value="KHK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774:SF3">
        <property type="entry name" value="KETOHEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774">
        <property type="entry name" value="PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="1">
        <location>
            <begin position="3"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="326" mass="35293" checksum="1026C2A2CFC4197B" modified="2014-05-14" version="1">MKHLIAVGACYLDTILTNVTSTAVPFFPSEDSKLRATSLNIRRGGNCPNSLQVLEQLLSEHDTLKLHLVSPLPAAASSATQRVISSFGAQSNIDFNHCVYREESTEAASSYIIRSEASGSRTLVNYNDLLEMTEDEFGNIARSFNLDQETWWHFEGRIPDTIQSCIGLLRNVLPKATISVEIEKPGREGLPELAAEADVVFYSRSWAESRGHKTPEQCLSAEGHQKASLALCTWGEDGAAGLSRSTGESLHCPALDESGRDISVIDAVGAGDTFIAGMLYGLICHPDDWSMGKKLGFAVRLATLKVQREGFDGLGRDMLGTEIGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0D0</accession>
    <name>X0D0D0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03574</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0D0"/>
    <dbReference type="HOGENOM" id="CLU_1777530_0_0_1"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK96574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="128" mass="14243" checksum="F6D38FEAFC70D9C9" modified="2014-05-14" version="1">MVLHLEANTCESGSDRDSIRGWVWDYYEIHGHWNHDHDDDFDCESCGAYFNMLSALLQHVESRASKVSAACNRVAYDAARKQPTSVPITAVQQYQYPIGPDSSESAAHPSRQFPDYGEDASGAAGFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0D138</accession>
    <name>X0D138_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 15">Aurora kinase</fullName>
            <ecNumber evidence="1 15">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_00653</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1 15"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D138"/>
    <dbReference type="eggNOG" id="KOG0580">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_6_1"/>
    <dbReference type="OrthoDB" id="377346at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032133">
        <property type="term" value="C:chromosome passenger complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051233">
        <property type="term" value="C:spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045143">
        <property type="term" value="P:homologous chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044779">
        <property type="term" value="P:meiotic spindle checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032465">
        <property type="term" value="P:regulation of cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090266">
        <property type="term" value="P:regulation of mitotic cell cycle spindle assembly checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902115">
        <property type="term" value="P:regulation of organelle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072479">
        <property type="term" value="P:response to mitotic cell cycle spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000819">
        <property type="term" value="P:sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14007">
        <property type="entry name" value="STKc_Aurora"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000235">
        <property type="entry name" value="Serine/threonine-protein kinase ark1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="125"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="75"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 13">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="203"/>
            <end position="205"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="252"/>
            <end position="253"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="12">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXL00501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="395" mass="44951" checksum="CB7175D5FE874057" modified="2014-05-14" version="1">MATRTIEARFERMSVNDENDPLGDGSKLYSKTKTMVSSTTSQSIHGASRPNLFKVALQSQSSNTNAAVMLPSQAAQRKVNNAPPSPTRKALPSSSRTSDEAQDERKSVTLPEQISVPKQFHLGMFEIGRPLGKGKFGRVYLARERTTGFICALKVLHKNELQAGRVEKQVRREIEIQSNLRHPNILQLYGHFHDSKRVFLILEFAGKGELYKHLRKESRFPEWKAAQYIAQMASALRYLHRKHVIHRDIKPENILVGIHGEIKISDFGWSVHAPNNRRKTMCGTLDYLPPEMIKPGTSDNFYNEKVDLWSLGVLTYEFLVGEAPFEDTPVMTQRRIARADMSIPSWVSPEATDLIKKLLVLDPEKRIPLEQIQQHPWIIKHCVKGERASNREKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4A8</accession>
    <name>X0D4A8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BCAS3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4A8"/>
    <dbReference type="OrthoDB" id="3938623at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045142">
        <property type="entry name" value="BCAS3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13268:SF0">
        <property type="entry name" value="BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13268">
        <property type="entry name" value="BREAST CARCINOMA AMPLIFIED SEQUENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1101"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL01217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1132" mass="121563" checksum="19FF0BFC91FDD0EF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7K9</accession>
    <name>X0D7K9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7K9"/>
    <dbReference type="HOGENOM" id="CLU_608369_0_0_1"/>
    <dbReference type="OrthoDB" id="5089539at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="422" mass="48669" checksum="E9AF1498A97482F3" modified="2014-05-14" version="1">MLPSTQPKRRGRPPKSSTLGGKLPGSKPRGRPRSTAPRKMSDKRITLTLGWRMRKFTMGKRVGDAARSVYRLSRQWPWDLVAGFVPKKWGVEILESLRRLFRITHQNFTVHDHRNDFQFVKDYLRECAMKHNRRRPHWKNSDIRDACDYFAHDNPARRDVIRRTMTRLRCSISTVVPEDEDGWQDYRGYDHFDDDDDDDDDEYVDIATPTKRSRTPSSPLLSPKRARTAESTEPRPQSITDITNSLQSLHAQKQKELKVETNSLGEITASIQAKEASRTNHVNAKIDRLTSDVKAYESKREKILKIRGFVEQQHEGMMMKADHLLQQYTSRLEECDKLIAQANADVLEELDQMARRDFDLEDEEKRLGGRVKEVLEEVRHCSVVGTLMRLGPSGMAKLLGRLEGNGVELVGMAESIMNETEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0D969</accession>
    <name>X0D969_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D969"/>
    <dbReference type="HOGENOM" id="CLU_1510668_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="178" mass="20671" checksum="6A90FA845D3DE8D8" modified="2014-05-14" version="1">MSVSPTVNQGDARMDSQILLEFALEAYLPGSLELYAPIHKLFEDRNSLVDPRYLVHGSIDLSQCLIEEITAFPQPSSKFGFEFWVIIEEATGVLDQVLYSRVRHKIDENFLTHIFKPHPFIFELVDQSLQFIIVSAASSEYRYPLAPYFECFNRDWYRPQNKACNFKTRHCSEGTKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0DAI8</accession>
    <name>X0DAI8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DAI8"/>
    <dbReference type="eggNOG" id="ENOG502SP6Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053392_1_0_1"/>
    <dbReference type="OrthoDB" id="203796at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848:SF1">
        <property type="entry name" value="SUN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="337" mass="37500" checksum="D7D3037DE725BBDB" modified="2014-05-14" version="1">MEKSAAVTEPEPSSPIAVLTGETPEHHVTLPPYSGPSIPSSAVSAPASQAIAAHKGPARFPGLPRVDYRLYSPPLFKLSNDYKTLSSRAEYLSAKPEALIALIRAQASVPPKPQIHIRGSRGRKVDFDIKLNLMSLLVPDDDNQRLDYLRCVGDGELAYRGGLKPDALPEVGDAGLDEWCRRFVQDPASVKLFTLERVVTNLDTAWLEGQFRSLVAALNYRGVVDVSFVVTHSRVVIQNPDKVNQFFTSVTSLFSGKHKYEVVKAVWPFATAKNGEPDRRCIVQSEETWWREWRDPIKYAISQKRHGWVTVEDKLEALMEGKGHETGIIDWGPENMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBA2</accession>
    <name>X0DBA2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_05865</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBA2"/>
    <dbReference type="eggNOG" id="ENOG502QQA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021993_0_0_1"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000286">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000308">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="59"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK91847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="445" mass="47814" checksum="02F87A7721AEDABE" modified="2014-05-14" version="1">MSSTATQTHEPIELTTLEGCHVRGKELEEQPSPPPDDIPPPYASAQVQRWNYPRGNIAKLAFAFLSFIIAGMNDAAVGALIPYLETYYDLSYTIISLIFLTPFAGYSVAAFTNARIHMKFGQRGVAIMAPICHLITFIALALHPPYPVLVVCNIMSGFGNGLTDACFCAWVGAMDKANTVQGFLHAFYSFGALFSPLIATSMVVSAGLPWYTFYYVMIGISVVEWVGLTVSFWQQTGAVYQAEHAANNSEGSGAGTREALKSKVTWLCALFFFAYMGVEVGLGGWVVTFMLRVRKASAYASGASGTGFWAGMALGRACLGFVTERFGERLCLSIYLLICIGLQLLFWLVPKFIVSAVAVAFLGFFLGPLFPGAVMVTAKLLPAKIHVSAIGFAMAIGGTGGTVFPFAIGAIANHKGVGVLQPIILALITVVAGVWLSFPRIKKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCS2</accession>
    <name>X0DCS2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502SDRD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004484_0_0_1"/>
    <dbReference type="OrthoDB" id="5232836at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="861"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="926"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="940"/>
            <end position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1472" mass="165683" checksum="E6AE3A3AE805A8F4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0DM91</accession>
    <name>X0DM91_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DM91"/>
    <dbReference type="eggNOG" id="ENOG502T40F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_771699_0_0_1"/>
    <dbReference type="OrthoDB" id="5106852at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="339" mass="38046" checksum="93634F1F0292EA42" modified="2014-05-14" version="1">MCEFNDDEISKDPNPFITVPPPSGSSGPQTSITVDLTQTPDSADGRRPKRTTGQKRKRATVTEEAEQLENIPSVKHVQADHDSIPTPFETPSTVDARQDPAVDTPDVAPPSQRSSSPLSPPPWLSDKPQPSTSQRRPSTPPRFSSPPLQRSSRWVGHDQDIPSLSHEPAKVSPRINGLRGLGEALMTNLEKTHERDRHQLIQLVLASSQGEGSCSADNLCLHRRQLIAAMDEPYRIKINWPQIATGEGADRPVELYHVICWDAMIDTERLLPKKLFPKMVENESGDFKKIGLMARQWLKYSGNVFPDRMSKILERLKTIVKPGDDIAEVWRLKFFRQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0DPV2</accession>
    <name>X0DPV2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DPV2"/>
    <dbReference type="HOGENOM" id="CLU_1970653_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="127" mass="14515" checksum="9F53A39B2AD1E41A" modified="2014-05-14" version="1">MWTKTSDTGARPVPSLMILFCPTIALHYVCVRRLLWPEADESNFERQSVIRNSRVQKELGMKRCHSPPRYTILHTHASSCMTTTWKTFIGAEIIAMQHPNMRGCRHLQRSIAMTLGASVETPWCRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0DSG9</accession>
    <name>X0DSG9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Y+L amino acid transporter 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_02457</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DSG9"/>
    <dbReference type="HOGENOM" id="CLU_007946_3_6_1"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF512">
        <property type="entry name" value="SOBREMESA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="557"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK97177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="600" mass="65081" checksum="41EEC7EAD93AC307" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DW96</accession>
    <name>X0DW96_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DW96"/>
    <dbReference type="HOGENOM" id="CLU_2306244_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="100" mass="11579" checksum="A3DC881A98EA86FF" modified="2014-05-14" version="1">MENHDKPARLETPFNFAHQQPRLPLVYRAHLMRRAVPGSGSPWETRLCLCLTRPGNFANVIVNECMETVFCQFEAGCISHFILFHSRLWFFVALSRSTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0DZH6</accession>
    <name>X0DZH6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_00015</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0059">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001640_2_0_1"/>
    <dbReference type="OrthoDB" id="8061355at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000335">
        <property type="entry name" value="ATP binding cassette subfamily A member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="792"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="970"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1011"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1047"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1078"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1114"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1161"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="449"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1226"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="740"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK99532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1552" mass="170314" checksum="64DB15D0116D23E3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0B108</accession>
    <name>X0B108_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="KI979813">
        <property type="protein sequence ID" value="EXK75790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B108"/>
    <dbReference type="HOGENOM" id="CLU_2671186_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="2">
        <location>
            <begin position="14"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK75790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="75" mass="8863" checksum="1819B1FF0C04F406" modified="2014-05-14" version="1">MAKTDDNHENDSIYLVDSIQDHFVDEDGCMYFQVKWQGHESSKEWTWEPQTNLESVACFVPLRSAELTLEIRRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3T2</accession>
    <name>X0B3T2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979515">
        <property type="protein sequence ID" value="EXK76411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3T2"/>
    <dbReference type="HOGENOM" id="CLU_2960824_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="59" mass="6443" checksum="1F75905A5E65C4D3" modified="2014-05-14" version="1">MAITGGPPESPFEEDEWASCHTLATEVAVGTLGLTVVKRLVIRVSFLYWRCPFRCASGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0B528</accession>
    <name>X0B528_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heterokaryon incompatibility protein s</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18092</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979407">
        <property type="protein sequence ID" value="EXK77195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B528"/>
    <dbReference type="eggNOG" id="ENOG502S8GV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058675_0_0_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029498">
        <property type="entry name" value="HeLo_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021084">
        <property type="entry name" value="Het-s_prion_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542:SF3">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14479">
        <property type="entry name" value="HeLo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11558">
        <property type="entry name" value="HET-s_218-289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prion-inhibition and propagation HeLo" evidence="2">
        <location>
            <begin position="6"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Het-s prion-forming" evidence="1">
        <location>
            <begin position="222"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="32312" checksum="B727549665948C7B" modified="2014-05-14" version="1">MAELFGAVAGAISIAGLFNNCVDCFNYVQIARHFGQDFSRYQLRLDVAKSRLARWGASIDINNNRRFSLIEPADPTVISAQDILQEIVARFETARKISRRYETRTEEQGLRIYTEADLGPVSHRLHSRFDGITKQRYKSLGLMKKTCWALYDKSYMGRMIDDIIASIEDLENVFPSTPQLTSQLVQMEIEEINDEQELELIHDVTEGVDPVLSDASKNKSLEIAGKNSAGRITGPGRVNIGNSFLTESFANSQRVRVDTVNHVDEINTAEPSRVYIGNTWGGKGFWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0B701</accession>
    <name>X0B701_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">O-methylsterigmatocystin oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_17736</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979384">
        <property type="protein sequence ID" value="EXK77551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B701"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_3_1"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK77551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="60102" checksum="92F9F6E2FDC10791" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8F1</accession>
    <name>X0B8F1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658521">
        <property type="protein sequence ID" value="EXK78420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8F1"/>
    <dbReference type="HOGENOM" id="CLU_1209879_0_0_1"/>
    <dbReference type="OrthoDB" id="5110227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="199" mass="22889" checksum="A4C853392EA86C8D" modified="2014-05-14" version="1">MHTSQSGSELDFMWTNGIELAFRITVQSNFFRVMDSGPGNLTFQLWTEEFRCALILKVTTSASREQAEMAHNAVQKIRNTERKEESDQALQSQTSTNLQGQSNHLEVMYHRGMFSITDGARQKDVKVDSFGQEEGVYIWIHDGKLIAGGPKLTEELRKIFGIEEKKKQLMKMMQDKDEAAAYWMQSIQQFLPSWYGGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAX2</accession>
    <name>X0BAX2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2,2-dialkylglycine decarboxylase (Pyruvate)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_16445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658493">
        <property type="protein sequence ID" value="EXK78921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAX2"/>
    <dbReference type="eggNOG" id="KOG1404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_0_1"/>
    <dbReference type="OrthoDB" id="10261433at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45688">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45688:SF13">
        <property type="entry name" value="ALANINE--GLYOXYLATE AMINOTRANSFERASE 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pterin-binding" evidence="4">
        <location>
            <begin position="402"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK78921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="456" mass="49489" checksum="251553A8783BF7DA" modified="2014-05-14" version="1">MSSNNQDSNHECRSLYPALDEDELARKSNAYLGNIGVSYRKELIVRSEGRSIWTASGHKFLDWTSGQMSCLLGHGHPEIVKVVAEHAAKLDHLFTGMLSPPVISLAERLCNMLPPGLDRAFFLSTGGESNEAAIKLAKVFTGKFEVVGLGASWHGMTAQALGVQYRYGRQGHGPNMPGMFALPAPNSYRSIFRNHDGSHDWEKEMIHGWSMIDMQSCGSLAACIVECIQSSAGIHVLPPGYLKALKRECEKRGMLLIVDEAQTGIGRSGDLMAIMHEGVVPDIVTLSKTLGNGLPLSAVVTSTEINDLCAKRGYCMYTTHANDPLPCAVGDKVLEIVMRDNLVENVRALGNILHAGLRNLQSKYNCIGDVRGRGLMAGVEIVSNRETKAADVELGQQIAENAFRRGLWANLSSDSYFSGTLRMAPSITSTEEEILEGLRILDEAFATTPGTQGLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBD4</accession>
    <name>X0BBD4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979595">
        <property type="protein sequence ID" value="EXK76128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBD4"/>
    <dbReference type="HOGENOM" id="CLU_3160062_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="48" mass="5590" checksum="87E1D9CE9140005F" modified="2014-05-14" version="1">MESLALAGSWFQRPTLLERSCSNSKFRFTCSKPHYRATGNCHYQVHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBP8</accession>
    <name>X0BBP8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658477">
        <property type="protein sequence ID" value="EXK79196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBP8"/>
    <dbReference type="HOGENOM" id="CLU_000288_63_40_1"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14014">
        <property type="entry name" value="STKc_PknB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053235">
        <property type="entry name" value="Ser_Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361">
        <property type="entry name" value="MITOGEN-ACTIVATED KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="49"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="337" mass="38170" checksum="2ADD008B160ABBF0" modified="2014-05-14" version="1">MSRSTRKDLPHHVRDFKITTRILDNRNVIHFLDDPEAPPFAPKLEQHWEREKHPVGRGGQGRVYLQTCTKGPAKGTIRAVKTLKLQQDNQRQRYVSELSTIARFSHQKYSKYFVKTLGYYESKTKLHIAMDYYPAGDLQDHIQNRPCLPEADVRQIISQVLAGLAVMHKQDYAHRDVKPKNILIQQHPDSTGSGSWWVKLADFGISKSLEVNRGNTSTIMGTPGYMAPELEDRAKRSNINFKAADMWALGVMAFFLSTKHDMFSSIRDVLHYEADPIRLFPNGRLGACQVSTDGQNFIRALTAPKPDGRPDSSIASQLPWIQTSMSDLPDIPDTGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBV6</accession>
    <name>X0BBV6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Laccase-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_18954</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979548">
        <property type="protein sequence ID" value="EXK76298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBV6"/>
    <dbReference type="HOGENOM" id="CLU_006504_5_0_1"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13850">
        <property type="entry name" value="CuRO_1_Abr2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13898">
        <property type="entry name" value="CuRO_3_Abr2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000036">
        <property type="entry name" value="L-ascorbate oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF488">
        <property type="entry name" value="LACCASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936849" description="Laccase-1" evidence="8">
        <location>
            <begin position="22"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="11">
        <location>
            <begin position="33"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="307"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="469"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK76298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="612" mass="67782" checksum="1596EA35249CA4EC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCG0</accession>
    <name>X0BCG0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658469">
        <property type="protein sequence ID" value="EXK79476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCG0"/>
    <dbReference type="HOGENOM" id="CLU_609789_0_0_1"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366:SF8">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="49312" checksum="D66E90EA677D4044" modified="2014-05-14" version="1">MILDGSISRATAEARRMGCFGHILNLVTQAFLYGENTAASALQYEEIRSTSLVRVEYRLRYGIEGQGANAKSGLGLVINAQRGFVLVSRAIVPNSCCNIQVTVADSAVLPASVKCLHPWHHWAIICYGANLVRVPVKSAKLITEDISQGQKITFVGCDGRGEIVEASTSVTKIIAHGLEPLCLRTARLINIDKIEVEAALNNECNTGFPIATDATVQGVWIAPESACLDNHRFGIDSQEIAAIAVKVSQGVDISFWRLPLELQSVKITEVEAMGVSTEWINKVLDERSDRRTSTAKRTWSQMPHQFQVGDILLSLNGKLVTRPSDLNITDPEEVYDVVASREGNEITVRASSTPEHDLETTRLTTFSGLVVHKPHRTMWQFIDKLPSEIWVANIYLGSPAHWYGVPSMCFIIYLDGKPVSCITSLLSVISQIPNNKGMFCAIAFLDTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD56</accession>
    <name>X0BD56_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979340">
        <property type="protein sequence ID" value="EXK80095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD56"/>
    <dbReference type="eggNOG" id="ENOG502RNQE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167710_0_0_1"/>
    <dbReference type="OrthoDB" id="4132874at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="113" mass="11786" checksum="E85C5C71F8E0FCE1" modified="2014-05-14" version="1">MSGSAPNDPAPGGQSRELQQTPFDSNQHGQAQNIIDETKSTGGRVVDANLGASIDATKSGELSSRVDDILNQPTGGRVGGTLSAQRKASEVDEKGFKVGEEGDFHNLAHSKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDR9</accession>
    <name>X0BDR9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979338">
        <property type="protein sequence ID" value="EXK80280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDR9"/>
    <dbReference type="HOGENOM" id="CLU_3175416_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="47" mass="5099" checksum="BA1375F035F03F60" modified="2014-05-14" version="1">MAEEDTRALSGIPEVKGGSRERNNFGALEGPRRHLDVNPSLHGARTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEM0</accession>
    <name>X0BEM0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Srp40 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979338">
        <property type="protein sequence ID" value="EXK80246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEM0"/>
    <dbReference type="eggNOG" id="ENOG502S112">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037040_1_0_1"/>
    <dbReference type="OrthoDB" id="5599646at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039191">
        <property type="entry name" value="Nopp140-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007718">
        <property type="entry name" value="Srp40_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216:SF1">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05022">
        <property type="entry name" value="SRP40_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Srp40 C-terminal" evidence="2">
        <location>
            <begin position="417"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="486" mass="51305" checksum="A12F63BA764694B9" modified="2014-05-14" version="1">MFELQQLSSGRYGTSGASSLPLASVYTSRRVSGESGSGFTLLHWRMSGSKQSPPSWLFSNNPLNPIKPSTDTMGKKSTKAAAPKNDATSAPPPGQLMDLVENFLSDHSFKGAADAFKKQREKKGWKATATTDEEGNPSLVSVYQTWEATKGDDSSKSSKSSKKKSSKKDSSSSASSDSSSDSSDAKEEDVDMKDAESSSDSDSSSDSDSDDEAAKPKASNTLKRKAPVDESSSDSSSDSDSDSSSSDSESDSDKPKAKKQKRAASSSSSSDSSSSSSESSDSSDSSDSSDSDSSSDSDDESAKSDSGSSSSDSSSDSSSDSDSSDSDDEAAAKVPLPDSDSSSSDSDSASSDSDSDSDAKETKKDKKIKKEKEVKDSSDSSVTLDKTSPDFQSNSAYPPLPPDPVVNGNGRKKQNEPFSRIPKNIKVDAKFASNEYVSIAYSQKAHEDLIVTKGKGFTKEKNKKKRGSYRGGAIDIHDKKGIYFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEY7</accession>
    <name>X0BEY7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979390">
        <property type="protein sequence ID" value="EXK77408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEY7"/>
    <dbReference type="eggNOG" id="ENOG502SUJV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5403641at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="165" mass="18589" checksum="20DC4078588B1D98" modified="2014-05-14" version="1">MSDRYDSFPFISLLSGWGVVSGPGLFMLRSLVSGISTATVVGVSSGMVGSMIWGTAGLPFLIGSSLGFAFGSYRWYEVATREAMVQLDLYPALLQMHITSNFPWVPDLHSRKRDWYTAETFRRSWVMKSMLVVGWLSAESSLREIRERREARLVEEYVAAEEESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGI4</accession>
    <name>X0BGI4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGI4"/>
    <dbReference type="HOGENOM" id="CLU_004184_7_4_1"/>
    <dbReference type="OrthoDB" id="3553147at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="58"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="695" mass="79183" checksum="127866D9228B3A03" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHK4</accession>
    <name>X0BHK4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Aconitate hydratase, mitochondrial</fullName>
            <shortName evidence="13">Aconitase</shortName>
            <ecNumber evidence="13">4.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_13943</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 18">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="JH658424">
        <property type="protein sequence ID" value="EXK81650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHK4"/>
    <dbReference type="eggNOG" id="KOG0453">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006714_2_2_1"/>
    <dbReference type="OrthoDB" id="2224430at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000002">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000004">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1060.10:FF:000001">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="entry name" value="Aconitase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006248">
        <property type="entry name" value="Aconitase_mito-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01340">
        <property type="entry name" value="aconitase_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005558">
        <property type="entry name" value="PRK07229.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF3">
        <property type="entry name" value="ACONITATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0408">Iron</keyword>
    <keyword evidence="9 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="14">
        <location>
            <begin position="71"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="15">
        <location>
            <begin position="598"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK81650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="808" mass="87803" checksum="3C8925D10955FAB5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIQ0</accession>
    <name>X0BIQ0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658423">
        <property type="protein sequence ID" value="EXK81691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIQ0"/>
    <dbReference type="HOGENOM" id="CLU_095752_0_0_1"/>
    <dbReference type="OrthoDB" id="5220117at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="264" mass="30026" checksum="1A5CE5835F21F8C2" modified="2014-05-14" version="1">MDECWQQEILSSRAFHNRKSRKFTPQVSSPLSITRILGSYQLQCPKAHSLARTSQCNHSPAKDERGVKHKRHPANSPRFEIHRFTDEEDGLEGDLFLPAVLDASFVMAGSRKKIHEILDRANISEEPDCHAESIAYSPGRRSADDSDADNQQHETCPEQQSSEVSGDEDDRPKEPHDCKTTEELRSDNFEKNTFRQPKFWLSWRGKVLVKPESDVVPEDHSPLDAIQSGIGYMVFTGNKYQKFKGTISCDILGWENVAITGWKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJ22</accession>
    <name>X0BJ22_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_13715</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJ22"/>
    <dbReference type="HOGENOM" id="CLU_021993_3_1_1"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000286">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF16">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="45"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK81846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="449" mass="48989" checksum="552093F366EF0828" modified="2014-05-14" version="1">MATVTQTDTRSETFELRSSPSPTRNVLDDTEPPHSSKPSTRELLKILSAGFSFFVAGVNDGSIGALVPHIIRDYNVTTAIVSSVYGANFMGWFFGAFSNTHLCQVFDLGSMLTLGAVLQVIAHALRSWKPPFPLFTITFWLASLGQAYQDTHGNTYVSGVKGSHRWLAFIHAMYMAGCLVGPFVATGVASAGSTSRWYLFYTFPLGIGVLNVAFVVYAFWDTLRLKRKQPPTERTLEADESPASRNDDAFSLMKETLKNKNVWLISLFFFFFLGATLTASGWVVEYLVEVRNGDINQMGFVPAGFSGGSLLGRLFLAEPTHRFGVRPMIFAFTILSIGLQVLFWLVPNIIAASIAISLLGFFMGPYFATGISVGSKLFNPRIQSTAVAFVFVFAQLGGCLFPIITGLIAASAGVSILQPILCALLVATSVSWLFVPMPKEGDNTTLHQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK96</accession>
    <name>X0BK96_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658495">
        <property type="protein sequence ID" value="EXK78884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK96"/>
    <dbReference type="HOGENOM" id="CLU_164890_0_0_1"/>
    <dbReference type="OrthoDB" id="10497095at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="125" mass="13608" checksum="F8A7F555EFC694C4" modified="2014-05-14" version="1">MRADLRVCDSVLHVSTTEGLRDRYPFGGVNDAALAEAEGVTAPTTRAAPSGSLPHLMLPPPRTSNNSDKILKEELHNVCAVAKWFFRQGVELSKSIMDGQLGKVGDTIRRILDLVVEVRVVQNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKV8</accession>
    <name>X0BKV8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_12885</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006477_0_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="42"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="699"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="732"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="1143"/>
            <end position="1165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK82770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1317" mass="149437" checksum="D3D72C6EE9B0313B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLY8</accession>
    <name>X0BLY8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alkaline ceramidase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_12830</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLY8"/>
    <dbReference type="HOGENOM" id="CLU_063293_2_0_1"/>
    <dbReference type="OrthoDB" id="187171at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187:SF3">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK82866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="38295" checksum="665EA7810328313F" modified="2014-05-14" version="1">MFEKLSLRIPYPPPQEGFWGQPTSTLNWCEEDYVISHYAAEITNTLTNLLFMALGVQGVRTCLKYKHDTVFVIAYLGYLLVGCGSFAFHATLSYPMQLVDELSMIYTTSILCYAIFTHDRSRLFSILLGIGLVVLSISITAYYHYIQDPSFHQNTFSILFLATVFRSLYTMEAILRPTLSNKYANKSRSTSLSDKEALYSPIRIDQAIIREMRWIVAMGFITCAAGIAAWTLDNLRCGDFVQWRHRVGLPWGILLEGHGWWHLMTGLGVNYFITWGIWLRHCLNGLQEQYILHWPHKLFSLPVVVPSAEHARYLKLRHVENDILGGTGLEKKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BN84</accession>
    <name>X0BN84_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658404">
        <property type="protein sequence ID" value="EXK83291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BN84"/>
    <dbReference type="HOGENOM" id="CLU_2740145_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="71" mass="8219" checksum="D80A33B1B65E9049" modified="2014-05-14" version="1">MGLLVARLSTFIVLSIEKTLQHQQNEARSDYIKSPGECDKKRLSYNRSTRFAKRTQRRETSAKSSSTKNDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPF3</accession>
    <name>X0BPF3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658447">
        <property type="protein sequence ID" value="EXK80354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPF3"/>
    <dbReference type="HOGENOM" id="CLU_2941786_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="60" mass="6700" checksum="87FD9A3BB47EE818" modified="2014-05-14" version="1">MDAELSWLGCLTSAGNLSNMELCTSPENLAVLELEKRPWCGLGRLLIVNRKAKRTQRPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQL2</accession>
    <name>X0BQL2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQL2"/>
    <dbReference type="eggNOG" id="ENOG502SSU0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045417_0_0_1"/>
    <dbReference type="OrthoDB" id="5057046at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="265"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="223"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="367" mass="40766" checksum="13B774F36CED2018" modified="2014-05-14" version="1">MSTSPCLDVHFTARAVIEWQSDHESDRTTRILAKPDPKVSSITLTARFDSKGSLFDIHIPLKLKGLDNTSDVTLRACASSVISLDVVKNPTVSSEVEQEFKSPALGLRFQLNRHLDILVPTPALEPICPAGRARSGVVLDAIREFSRATAFTVYIEARNASPKLQSVSDAVSQGFFKTSSSSRFQLASMYAGLGAKIVQLGADETLAPPSYEETEPPPPPPPIDHKPDRKRPRQDTETERAEEIALIWAELQMLKQAKATDWQRIAFLEKENQELRETVAKLQEQYKAFDKSQQDIHHSFGALETAVEKNTQEFEESVGNELAELREDISQLDHQLSFIQEGQVSDESVAKIKDAVLLDITSRLSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQS6</accession>
    <name>X0BQS6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14689</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658435">
        <property type="protein sequence ID" value="EXK80834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQS6"/>
    <dbReference type="HOGENOM" id="CLU_017584_0_5_1"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047536">
        <property type="term" value="F:2-aminoadipate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008793">
        <property type="term" value="F:aromatic-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009074">
        <property type="term" value="P:aromatic amino acid family catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF21">
        <property type="entry name" value="AROMATIC_AMINOADIPATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="156"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK80834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="504" mass="56284" checksum="5CC796ED6FCE1F94" modified="2014-05-14" version="1">MLKSKLSEIDNKRAASQPLPKSSAPYTCSTFFKVRQPGEKPVAKSWDHRFSEDSQRQHTSSLKAAARAAHPDMISLGTARPWAEYFPWKALEIICPGPEGLGSTVSMDCVKGEDEYDLDIVMNYGYAGGSPQVLRWVTEHMELLHDPPYSDWECAITCGTTSAMEIAFRLFCNPGDTILMESHTYTGTLSAALAQGLKIQGVAMDELGLVPEDLNHTLENWDLLKGPKPSVLYMIPCGQNPTGSTQSLERRQAIYRVTEAHDLYIFEDDPYYLIQLAEDSSEDSDKGLDADDYLRSLPASYLSLDVSGRVLRMDTTSKVLAPGLRCGWVTASSQVINKFIAYSEVSVASPSGPSQAMIYKLLGQTWGHEGFIRWAMMLSAQYRRRRDILSTACKAHLPSGICSWRVPDVGMFLWINLNLSYPSLAMNNKDSEWEAYRYMEDTIFSKAQENGVVVSKGSWFITNVTEMRGVSFRLTFAAAQEEGIDRAVERFGRAIRSYLDDPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRD1</accession>
    <name>X0BRD1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14115</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRD1"/>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF103">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="53"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="497" mass="54884" checksum="1D6F0C3B6A194854" modified="2014-05-14" version="1">MAIKDASETMDIKLEDKELDKTDLASVANGAILGRDLTPEEDRRILRKADLHLLPIMAFAYLFQFLDKTALSYTAILGLREDLNLKGEEYGWASAIYYFGFLVATYPIAGVLLVRLPIAKVIAVTMFIWGAILMFTALCRNAKDLLATRFFLGVAETAIAPGLSMIVAMWYKRSEQPLRQGAWFLGNTSAGILGGLISYGFGEINTFSPWKAIFICFGALTIAVSIMVLLFLPDTPANARFLTKDERVQAVARVETNMTGIKNDKWKKEQVMEALCDPNAWLLVVSYLASVIPNNGLLTFNTIVIQGFGFSVLKTLLLNILPSVFQLVFVLISVIGSTYLPNTRLLFMTFNVIVSIVGAVMVREVDPAHKWTRVMGCALGVAFTANFPMTMAMVSSNFAGFTKKSTVSAMVFIAYCAGNIVGPHLFFPSEAPGYKSGFLAVMICLAVSAVLCIILRFYLIWENQKRDNAGDAIEGPLEGINLSDKTDREIPQFRYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSA2</accession>
    <name>X0BSA2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979333">
        <property type="protein sequence ID" value="EXK81364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSA2"/>
    <dbReference type="HOGENOM" id="CLU_1496279_0_0_1"/>
    <dbReference type="OrthoDB" id="626167at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="180" mass="20136" checksum="75CC85ED830C3ABC" modified="2014-05-14" version="1">MERYFQLKVAFRHKVLNGQAFGLIDVSDAPADELYQVPGNGEWVALRLIIDHDGWRAAVARRREQSNPAVWGEAETETIVTARLIGMDKALGWLDQRLPTGPFPPQPRNPGISHACEIKQGLLLFKADRCGSDVNSPWHTQQELEKRDLSELSAICEYLLKQYASVDPGCSAPRKSAARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSD5</accession>
    <name>X0BSD5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSD5"/>
    <dbReference type="eggNOG" id="ENOG502QTW5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068925_0_0_1"/>
    <dbReference type="OrthoDB" id="10010954at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="38059" checksum="22BF73097F2D1FDF" modified="2014-05-14" version="1">MASSPQFDNSFLLYTFCLINCFRLYSPLAIMSDSAHHAHRVFVPKIQIIENNPLSHLLPYGSLILTTSIICIVLLTNCLERWILPAVYKDICQTFERTKDERRRRSFVYFHVGSIILFCVLCSGCYPMMYFLIGDAKFSTPFTKGSSVTIGDSLLVLSEVYSSYYIFEICFRTKFASPLSIAHHTGLLVITQTALSLFADHNKHREATLEFYMCMVWGTFDVIVELPIFLMMIVWRIKRHNTLLLSRMAYTCCVWQVTGAITEVAVTIYLLNRSWHRWGLEWRIITPLVFSLWITTQLYGASRLYQMGRGERQKLKAKDELALTQEESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTB8</accession>
    <name>X0BTB8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydrylase FUB7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fusaric acid biosynthesis protein 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_10801</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTB8"/>
    <dbReference type="eggNOG" id="KOG0053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_4_0_1"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071269">
        <property type="term" value="P:L-homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000035">
        <property type="entry name" value="O-succinylhomoserine sulfhydrylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797">
        <property type="entry name" value="HOMOCYSTEINE/CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797:SF2">
        <property type="entry name" value="HOMOCYSTEINE_CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00071517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00083302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK85146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="433" mass="47096" checksum="07F051DFEE17F604" modified="2014-05-14" version="1">MAEQVFQNFETLQLHAGYTPDPHTRSTAVPIYATSSYTFNDSAHGARLFGLKELGNIYSRLMNPTVDVFEKRIAALEGGIAAAATSSGQAAQFLTIATLAKAGDNIVASSHLYGGTYNQLNVLLPRFGIKTKFVRSGKLEDYAAAIDDQTRAIYVESMSNPDYVVPDFEGIAKIAHEHGIPLVVDNTLGAGGYYIRPIEHGADIVVHSATKWIGGHGTTIGGVIVDSGRFNWNKHSDRFPEMVEPSPSYHGLKYWEAFGPATFITRIRVEMLRDIGACLSPFSAQQLLLGIETLGLRAERHAQNTEKLAKYFESSPNVSWVLWPGSESHPTYAQAKKYLTRGFGAMLSIGVKGDASAGSKVVDGLKLVSNLANVGDAKSLAIHPWSTTHEQLSEDERLASGVTEDMIRISVGIEHVDDIIADFEQSFQKAYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTI8</accession>
    <name>X0BTI8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7357 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502SF1H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5368821at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055781">
        <property type="entry name" value="DUF7357"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24054">
        <property type="entry name" value="DUF7357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7357" evidence="2">
        <location>
            <begin position="5"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="779"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="881"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="977"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1124"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1413"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="521"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="545"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="695"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="712"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="736"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="832"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1084"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1147"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1205"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1273"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1288"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1306"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1378"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1414"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1459"/>
            <end position="1474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1497" mass="165588" checksum="C7AB47D60F0E32C6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTV1</accession>
    <name>X0BTV1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658419">
        <property type="protein sequence ID" value="EXK81924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTV1"/>
    <dbReference type="HOGENOM" id="CLU_880115_0_0_1"/>
    <dbReference type="OrthoDB" id="5108869at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="347" mass="38711" checksum="C497F6ABC0913699" modified="2014-05-14" version="1">MTNAGNKFKYYPSETTDHNNRQTSIPGLPTTANPIQHFPILYRPSGAIVYDGTNAGDVPVFWGPKERCHYSQVPKPLDSLWVKLCYSAGAHADSPDGKRLPALAYALSDDVAKLLLQHGANVNVTHSTDETALCHLMSWGPMENRNWYQESHTLQGNGALKPSHARQDSLSTIKFFIHNAMTYIYVDKFENVSLLQLVVSKRYTEVAELLLAVEASPNLINSDTGQKRFVLVDALKQGRNLPIIQLLLKAGAEAELNEMPDNGLTREEGAELPIMHLTVSGTNPLYAREEVKVAGMVCKRIKRFNTAIDKHLALWHYIIKGRFKCGSSRYFFEACNELIIARVCRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUI2</accession>
    <name>X0BUI2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tryptophan synthase beta chain-like PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUI2"/>
    <dbReference type="HOGENOM" id="CLU_021018_1_0_1"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="1">
        <location>
            <begin position="12"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="334" mass="35179" checksum="234350A2A59B7591" modified="2014-05-14" version="1">MPLNPPKPVSSILDAIGNTPVVKLRHVVPENCADVYVKLEFFNPTGSYKDRMAKSMIEEAEHRGSLRPDMVVVEATGGSTGSSLAFVCSAKGYHFLALSSDAYAAEKLKTMSAFGAQLDITHSPSGKATADLMASMKSRAVELGKGGNYFYTEQFSNRDALIGYAEIGSELVAQFPDGFDVICGAYGTAGMIMGVSSVLRQKMPAARVVLLEPTSAAMLSTGQSGSHSVDGIAPGFISAHVDQHLYDEVRTVTEDESRQMTRRLAKEEGLLVGTSSGLNVAAAIRLAKSIGPGKKVVTVAVDTGLKYLSGSLFGEESTGTKVENGPVVTSSNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUT4</accession>
    <name>X0BUT4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Negative acting factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK85949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK85950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUT4"/>
    <dbReference type="HOGENOM" id="CLU_013866_5_1_1"/>
    <dbReference type="OrthoDB" id="4220372at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DBAG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="50223" checksum="86F5D83E97A64E0F" modified="2014-05-14" version="1">MSFFSNPRLLPVSSNDKQGVSVRPKVHQSKDRSNHYPWFRLAVTPEDQALHFFFHHYVVPESGRSPTHPDCHGIIYKRATGPGYLADLINAVGLAGLAYMRSKPTLISVASQALSRALHGICAALMDPSEASSDQMLVAVMLLAWYETSTFGSNANLSSWSRHVDGALSLIQLRGGGQLRNRIGRSIFLHLRTEILIDCLQRGLRVPKVLTDFMAEARSNETEQEAPAARLADIIVNVCAVVALAKEEITDEMNLSSYVSALLSIDTDLKEWAQNLPVEYEYKTRTHPSAREEAEVFMGRYDIYSSVEIANTWNLQRCARIILRQALVEAISNRLPISSSLSILSSFPVSYTDLLLSSETIIQESSSDICDSVPYILHIDVAGKSSDLRAAHVVHLLWPLYITGTTHTATDALRHWVISTMGDIKDATGIQKAKLIALSLQQRCSEAVTFTCIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVA4</accession>
    <name>X0BVA4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="14">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_13152</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="14"/>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVA4"/>
    <dbReference type="eggNOG" id="ENOG502QVVM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004624_7_0_1"/>
    <dbReference type="OrthoDB" id="1887033at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938892" description="glucan 1,3-beta-glucosidase" evidence="17">
        <location>
            <begin position="17"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="18">
        <location>
            <begin position="88"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK82439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="430" mass="49377" checksum="86D72100138CC30D" modified="2014-05-14" version="1">MHLKLALHLFLAVAEAWTPQSRTAAKANGEKITERWLPNDDKIRGVNLGSQFIIERWMAEESWKNMGCSAYNDEWACVKGIGQDKANAAFKKHWETWITEDDIKQIASLGLNAVRIPVGYWMYEDIIQKGEYWPRGGIWHRDGHRILCNDAALNPSLIWHLDRIVGWCKKHGIYAVIGLHSAPGISSPNEQFTGHSIPNPGFYTAENYERAFKFLEWMTKRIHTNGNYTTVGMLEVLNEPVRAGKWKAEADDMIKNYYPGAYKRIQAMEGYLKVPKADRLHIQYMGKSWGAGDPRQYLPDDDLIFFDAHRYLSFDNRIAGNKKAYIQTACKDNMGQHVFVGEWSLSVNSTLKNTDEFKIEGQETWYKAYWAAQAESFEKSDGWFFWSWKCDGDLGKKDWRWCYQAAVAAGVIPKDASKAKSLSPCARYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWP9</accession>
    <name>X0BWP9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWP9"/>
    <dbReference type="HOGENOM" id="CLU_171963_0_0_1"/>
    <dbReference type="OrthoDB" id="5101596at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="113" mass="12445" checksum="A1578D90D1EA1FD8" modified="2014-05-14" version="1">MADPAQQAHIQNAKEQLKAAYSHAVSAKESAESQFKQQQDAGIADGQDFTNWSLQNAPAYYAALQQYKYAKAGYDAALQNGDREAFSAWDKKYKDAVLANNPAKPDYDALVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BY31</accession>
    <name>X0BY31_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BY31"/>
    <dbReference type="eggNOG" id="ENOG502SIR2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028280_0_0_1"/>
    <dbReference type="OrthoDB" id="68575at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936666" description="Amine oxidase domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="50406" checksum="43C10468A79EF073" modified="2014-05-14" version="1">MVSSKLLFLAVIAAVQAIDVDVAVVGGGGSGGYAAVQLRENYGKKIVVIEKQKQLGGHAQSWYDPVTGKAYNYGVDAFTNITVSIDFFKQLKVPIGPVQFEQVRNLYVDLKDGKTVDYTPPTTKEAADAMGNYRDQWLKYTDILLPTSEHFPRGDKVPSDLLLSWYEFARKYKAEAASPSIWDTVVVDLNTALMIDVWKAWNPSVGSFQPASGDNTEIWQKAAKVLGKDVLYESEVVSAKRSKSGVKLQVRDKDGQAININAKRLLITIGPETINPKYFDLNSEELEVFHSAAGNRYYTGIVSHPSLPAAEITNVVPAAINENYLAYPTVPFQAYFHYKGNSSTGPIHRALAIVPRDTSIEDAKGLIRKSLQNLIDAGTIQAGNSTDLDFRTFSDHGLLYRRWSADQLRGGIFAKANALQGQRSTWYTGAFWMNNDCVMLWNTTNAILKEMLKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZK9</accession>
    <name>X0BZK9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZK9"/>
    <dbReference type="HOGENOM" id="CLU_1525230_0_0_1"/>
    <dbReference type="OrthoDB" id="3435011at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="20431" checksum="ABD2C56823390E64" modified="2014-05-14" version="1">MSASPEPFTLFHKFPPELKLEILNFCSRNDLVCLSLTGPDMRNLVTPLIPSKPNLTWVDQLGPTPDVPSECRDPYHNNIPRRPGCDGAREQEVIYFPTGHRFRRHEYRGCKALTGGKRCEKHQTTIGVVAKDYPTEIDGGENGVHMGLTTRHTSPKTPEDETQESFNRVIYSKRDPILLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZS7</accession>
    <name>X0BZS7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xaa-Pro dipeptidyl-peptidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZS7"/>
    <dbReference type="HOGENOM" id="CLU_015590_3_0_1"/>
    <dbReference type="OrthoDB" id="2578740at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF10">
        <property type="entry name" value="COCE_NOND FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="2">
        <location>
            <begin position="341"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="616" mass="69358" checksum="443BB9F99EBA43DE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1C9</accession>
    <name>X0C1C9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_10946</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CKS family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1C9"/>
    <dbReference type="OrthoDB" id="440676at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.170.10:FF:000002">
        <property type="entry name" value="Cyclin-dependent kinases regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00296">
        <property type="entry name" value="CYCLINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00945">
        <property type="entry name" value="CKS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00068939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK84993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="125" mass="14799" checksum="19F5AB8D68FC0F00" modified="2014-05-14" version="1">MPFDIDTARRNKTPRPLSDSERARVEEFIDSIHYSARYSDSEYEYRHVQLPKAMLKAIPKDYHDTSKGTLKLLWEEEWRALGITQSLGWEHYEVHEPEPHILLFKYVVMAIPMLGSTLHVSRWLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1T0</accession>
    <name>X0C1T0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="4">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_08638</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + H2O = 2 phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1T0"/>
    <dbReference type="eggNOG" id="KOG1626">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040684_0_1_1"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.80.10:FF:000004">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="64"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="368"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="370"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK88370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="418" mass="45652" checksum="8E20AF888A339990" modified="2014-05-14" version="1">MLQPQSSRLLLLQRSLRTTVTGRSRGTGTTATGTLLYSPSAAPSLSPYRVPGRANYMASLAARSPAAAGPGGSNSAVTSGAPPPPSSSYSHSAATSTSKISSRRTAQIARHFSSSSSPTGPVSKQKPDMASNYTVRKVAAPNTLEHRVYIEKDGQPVSPFHDIPLYANQEQTILNMVVEIPRWTNAKLEISKEELLNPIKQDIKKGKLRYVRNCFPHKGYLWNYGAFPQTWEDPNSVHPETKAKGDNDPLDVCEIGELVGYTGQVKQVKVLGVMALLDEEETDWKVIVIDINDPLASKLNDVEDVERHLPGLLRATNEWFRIYKIPDGKPENQFAFTGECKNKSYALDVVRECAEAWERLITGKTPAGGVSTTNVTVQNSPSRVSPDQLPPLPPNEDVPAEKIDASIDKWFFISGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1T3</accession>
    <name>X0C1T3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxidase FUB9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Fusaric acid biosynthesis protein 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_10799</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1T3"/>
    <dbReference type="eggNOG" id="KOG0538">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_0_0_1"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000056">
        <property type="entry name" value="hydroxyacid oxidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF149">
        <property type="entry name" value="2-HYDROXYACID OXIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="9">
        <location>
            <begin position="18"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="97"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="305"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="328"/>
            <end position="329"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00073420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00083297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK85143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="387" mass="41288" checksum="4DB7E7CC2AAF0C38" modified="2014-05-14" version="1">MSRTNLPIQPAKMSDATSSKPQIFSIQDLKQAASDKMSQMYRDYYNGGAMDNITLASNEAAFDRYLLRPRVLRNVSNIDMTTTLWGTKVALPLGVSPSAMHRLAHADGEVGTSKACAARNVPMILSALSNDTLEDVSGQSSDGSTPYAIQVSPFKNRQITTNLLSRAKAAGYKAVVLTVDAPMFGRRLDDLRNGFSVPPGFSFPNLSAQTQSGSGGLGGGIPDLSFDTAATWEEKIAWMKSQTDLEIWVKGVTSPLDAQIAIEQGVDGIIISNHGGRQLDTTPATIDILREIAPIAKGKTRIAIDGGFRRGSDIFKAVALGADFVFVGRIAIWGLAYDGSNGVGLALDLLINEFKLCMGLAGCSKISDITPAHLSILNAKGVLESVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2E2</accession>
    <name>X0C2E2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2E2"/>
    <dbReference type="HOGENOM" id="CLU_180198_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="86" mass="9818" checksum="E485CE1738E2D095" modified="2014-05-14" version="1">MPDITEVTTPKIRNDHTHWRCMHETDGTECNTRLEMTQECCTECGSSRKEGSYAEAHDGYQLGTLESFEPDGKAIWHYTFIKNGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2N2</accession>
    <name>X0C2N2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBM-cenC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10518</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2N2"/>
    <dbReference type="eggNOG" id="ENOG502RAME">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1102824_0_0_1"/>
    <dbReference type="OrthoDB" id="5102593at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003305">
        <property type="entry name" value="CenC_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02018">
        <property type="entry name" value="CBM_4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936141" description="CBM-cenC domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="CBM-cenC" evidence="4">
        <location>
            <begin position="143"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="18"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="295" mass="30493" checksum="0A4ABA0DF4CFB7A4" modified="2014-05-14" version="1">MRFTHPALLLALCQIASSSPCKPSSSVTSSAPTSTDNESASSATETSTAISVETGSSTISHDTTLAASETASASELSISTTLVSTSSAEPTTTLEATTDLSTTLDETTTTFESETTSGSATLISTTTAEASTTTSAAPEIPSNRVLNPGFEDNSVVPWQSMSGTLSPSSSEVHTGSQAGFFSGTTPMSAMMGSRQFINPTWITPGKSYKFSAWVKITNTVNCGYRTIVCGHGAGQGTTSSVGFITETGDFSLASVTCSWTQAQWEAGPSVQIRSYCTGLSFFVDDATLEEVETLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C304</accession>
    <name>X0C304_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arginase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10614</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C304"/>
    <dbReference type="eggNOG" id="KOG2965">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_888765_0_0_1"/>
    <dbReference type="OrthoDB" id="9992747at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004053">
        <property type="term" value="F:arginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782:SF3">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="34579" checksum="1A2DDF24C9EF6DBF" modified="2014-05-14" version="1">MAASRSVSVTYVPADCGSIIPGKSKAPQAFRDVGIVSKLRDAAVPSVSEHHALKAPATFSATTFSAGGARNEDINISVCEDVERTISNNFKSSSKQPEFQLVLGGECCMLPAILSAFWKHADSQSQPKRVGLIYIDADTDLTSPTDPSSIGTFAGMNMAHLVRLSGALPRMEQFSRSSGEPVCDASNTVFFGTNMSLPGNKPEHFKYLFDNNFKVVSSASVAKDPEQRARETLEFLQDKVDIIMVHLDVDSIDPGTFPLANVPNFTGVEFENMMRALKVLLGSEKVGGLTVAEVNPDHDPGLKMTERLTSHIVEMLAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C392</accession>
    <name>X0C392_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10628</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="2"/>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C392"/>
    <dbReference type="eggNOG" id="KOG4127">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031404_4_0_1"/>
    <dbReference type="OrthoDB" id="445695at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01301">
        <property type="entry name" value="rDP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="388"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="414" mass="45962" checksum="56C1BA8FD7EFA043" modified="2014-05-14" version="1">MASTHPYQVLPIDEGVKRVLATTPLIDGHNDLPQQPRACFHGQIHNNEKFDLEKGFERGMTDIPRLKQGAVGGQFWSVCVPCLRSAENFTTPEYSDMARDAIEQIDLTLRLVESYPETFQLVSGPSEVMDVYAGGKIACSIGIEGLHMAGNSIGIIRAFYRLGVRYCTLTHVCNNAFADSSTSTIGPVHGGLSDLGRAAVKEMNRLGMIVDLSHVSEDCASQVLDLSRAPVMFSHSNAKGVFDCPRNVPDYILDKVPVNGGIVMVTFVPEHVTTRRRDAKMEMVIDHLFYIANRIGWDHVGLGSDFDGIASVIPGLEDVKCYPHLLKAILDRGATEEQLAMVVGENTLRVWAGVEKVSDEMKAEGVLPVEDVFKDRKWWRYDGYYQMEDPDPEDKLGLDWYGKPPPDEGLYLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>X0C484</accession>
    <name>X0C484_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_10051</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK85993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C484"/>
    <dbReference type="eggNOG" id="ENOG502S6QC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010813_1_1_1"/>
    <dbReference type="OrthoDB" id="4116913at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="6"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK85993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="622" mass="70325" checksum="484BC80FCB35E9C4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4T3</accession>
    <name>X0C4T3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4T3"/>
    <dbReference type="SMR" id="X0C4T3"/>
    <dbReference type="eggNOG" id="ENOG502SYF8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1806250_0_0_1"/>
    <dbReference type="OrthoDB" id="2131701at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="10"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="167" mass="18280" checksum="3C96E303C8AF6772" modified="2014-05-14" version="1">MSMISAHDLEGKTVAFVNFATGTAIDLKDGFTSPPDGTPCIGWQAHLNENQQWKCVKYQHGPDDQPQFRLQNIRASGRAMDLYNGGTSDGTEIVGWQYSGFGGHQLWCIRPVGYFPAHGTIVKIENIPAGTFVTLQGGSAQYGTRIVGSHGSLNDLRTDQLWILKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5C9</accession>
    <name>X0C5C9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_09655</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5C9"/>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07105">
        <property type="entry name" value="ALDH_SaliADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF6">
        <property type="entry name" value="CYTOPLASMIC ALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="28"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK86383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="482" mass="51597" checksum="80A1B7B560AF57E2" modified="2014-05-14" version="1">MTVPTESGTGASVPLIIGGHPIITESLFDVISPNTKKVIHQSSNAETTHALAAVSAAAKAFETWSQTTPTQKRAIFLKAVEVLDKRTDELKGYMLTETGSDEGWAVFNVHLARECLLDTASRITALEGRVPTLQDPSAGAIVVKEPFGVILAIAPWNAPYALGFRSVAWAIAAGNSVVFKGSELSPRTLWAVGSVLQEAGLPDGVLNFLTCTPQNAPSVTKTLIENQEVKKINFTGSSGIGRVIARLAGDNLKPILLELGGKAPAIICEDADLDVAAKQCVLGAFMYSGQICMSTERIIAHRSILAELEEKLKQTVDDIFSSGNDAPILIADRAVDKNKDLVKNALSMGAKLVYGNVDAVERTPSRLRPIIVSGVKPGMDIYATESFGPTVSVIEFDTEDEALKIANDTEYGLSAAVFSKDLRRALRLAKRIETGAVHINRMTVHDEAVLPHGGAKSSGFGRFGTGMGLEEWVRTKNITYDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5V5</accession>
    <name>X0C5V5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_17192</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658544">
        <property type="protein sequence ID" value="EXK78127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5V5"/>
    <dbReference type="HOGENOM" id="CLU_024810_2_0_1"/>
    <dbReference type="OrthoDB" id="18453at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF22">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05462">
        <property type="entry name" value="Dicty_CAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="320"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK78127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="364" mass="40764" checksum="2DD4BA818F9EA07D" modified="2014-05-14" version="1">MADSFIREPDGAGCQTQAFLLHTFVGADALWTLAMAINVNLAFYYRFDAQRLRKMELPYLILCYGIPFLPAFIFIFIRNGDGDRVYGSAVQWCWIVPSWDALRIATFYGPIWGVIAITLAIYIRSGGTIYRKRQQLLKAQASGSGSGGLSYANQSTINNMKTTEVTITREAAGETNAVELQSMGHQASVHVIRDDTRSGESRTAQVTTHTSSTTSQPTVPRPPGRVSNDVYRAAWAYTKVAMLFFAVILITWIPSSANRMYSHIHPKEVSKPLQFMSAIVLPLQGFWNAVIYAVTSWASCKALLEERGFWGSRTRINEPANWEAEESRSNRRSKLKTMLKSRTEDSESLRELAYPTKSDDGRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C639</accession>
    <name>X0C639_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_07705</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the polysaccharide monooxygenase AA14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C639"/>
    <dbReference type="HOGENOM" id="CLU_030284_1_0_1"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054497">
        <property type="entry name" value="LPMO_AA14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22810">
        <property type="entry name" value="LPMO_AA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936979" description="Proteophosphoglycan ppg4" evidence="12">
        <location>
            <begin position="17"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK89616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="32043" checksum="56F984C6938F55AF" modified="2014-05-14" version="1">MYTSTLLLTLVASASAHIASWNKGMYCKGGNDSSVDNANTNLAVNPLYDLPKSKWWMQADRGCDAVPPPKGEFLELPAGKSFMTELANNRAFTTLSYKGELTTEWQDGKNRSMPWRGPEGGCLMDGGDGSGGELHTKNIESTGGTAWAISYESDISKVTMDNLVVFSVRYYSPFFRETWYDVPADMPACPEEGCYCAWLWIPDGCGQPNMYMQNHRCKVTGSTSTKKLGKPKPPVYCRDNPTKCVPGPKQMMAWNQAEGNNVNPPNGKTPTYNQRMGFMDGAQDDIFVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-01-24" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C642</accession>
    <name>X0C642_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C642"/>
    <dbReference type="HOGENOM" id="CLU_2812413_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="1">
        <location>
            <begin position="30"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="67" mass="7751" checksum="9818B3AB151158FF" modified="2014-05-14" version="1">MSSLLPVLAPRLPGCPPAVDDRTYTKEHTEEEWESMRNVIRKLYIQENRKLNETMAILQARYGFAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6U5</accession>
    <name>X0C6U5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658518">
        <property type="protein sequence ID" value="EXK78452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6U5"/>
    <dbReference type="HOGENOM" id="CLU_1896313_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="134" mass="14962" checksum="6B6D349C927E228E" modified="2014-05-14" version="1">MSFSDPSEPSYPPPGQGDQLLGSIPTQSDSTCNSDPSSAWRAGQEPGPSHGSQYLSEIRQLHEIMCEVQQDIGELKRDFHDFRNQIKRKRYLKQANASRPLSITTRRKMRNACCGKRKSSLRAIPSTGTPDIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7G7</accession>
    <name>X0C7G7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Cytidine deaminase</fullName>
            <ecNumber evidence="4 13">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 13">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_09559</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 13">
            <text>cytidine + H2O + H(+) = uridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="4 13"/>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7G7"/>
    <dbReference type="eggNOG" id="KOG0833">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="414540at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055086">
        <property type="term" value="P:nucleobase-containing small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072527">
        <property type="term" value="P:pyrimidine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01283">
        <property type="entry name" value="cytidine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000069">
        <property type="entry name" value="Cytidine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050202">
        <property type="entry name" value="Cyt/Deoxycyt_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004064">
        <property type="entry name" value="PRK05578.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644:SF2">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="28"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="69"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK86739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="166" mass="17623" checksum="5D574289DC17C354" modified="2014-05-14" version="1">MMETPETISRGDTAKTAEVCSAHGITPKEFSELRERAVAAKATAYCPYSQFRVGATVLSSEGELTSGANVENASYPVGTCAERVALGTAVTSGHRGFRAIAVATDIAPPASPCGMCRQFIREFCTLDTPIIMFDKNEDVVIAKLRQLLPMSFGPDQLPPPGAPGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-09-13" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8K3</accession>
    <name>X0C8K3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8K3"/>
    <dbReference type="HOGENOM" id="CLU_171236_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936227" description="EthD domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="113" mass="13282" checksum="C13D0FCEBEAFFD8D" modified="2014-05-14" version="1">MPPFALIFKFAIFFICRAMALLSPRDAIHINDLERYDTFMKTMAGTQYLHLYPGNQVIKLDVYEYPSDELVKSGEFKPSAKADAYWGKEDEFEKEFLGRQECHKEDELELKMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C967</accession>
    <name>X0C967_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable Xaa-Pro aminopeptidase P</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_06537</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK90980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C967"/>
    <dbReference type="eggNOG" id="ENOG502SKA5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052604_0_0_1"/>
    <dbReference type="OrthoDB" id="9995434at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01066">
        <property type="entry name" value="APP_MetAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050659">
        <property type="entry name" value="Peptidase_M24B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46112">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46112:SF2">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase N-terminal" evidence="3">
        <location>
            <begin position="37"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="2">
        <location>
            <begin position="194"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK90980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="419" mass="46944" checksum="5917741C294A3FEE" modified="2014-05-14" version="1">MANFDWHAERTDLSDLALLDRAPESEGIDLKAVRLYRLDRTRSQMVKYGLDAAIISDPVNIRYVTGTRNMQVFTARNPPTRYLLLTATRSIMFEFAGCLHLAQGYETVDEVRTAKSVTFTSSGPKVHDKERKWAQEMADLVESLIGKRNATLGLERMNANVAITLKELGLNIVDAQQAIEMARTIKSPEEVKCIVASLRATEVAVGKLRDAVSPGLTENQLWSVMHKSVIEQNGDYVETRLLGAGPRTNPWFQESASYVIQKNDLVALDTDVVGCHGYYSDFSRTFHAGPDPPTEEQKELYRTALAQVNHNMSILRPGLTFREYADLAWDIPEQYWANRYFVSAHGCGLTGEYPYLYHRGDFPDAGYDGVIEPGMVLCVESYIGKEGGTQGVKLEQQVLITETGIQVLSKFPFEEAMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAJ2</accession>
    <name>X0CAJ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAJ2"/>
    <dbReference type="eggNOG" id="ENOG502SI3S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017444_4_1_1"/>
    <dbReference type="OrthoDB" id="1911848at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056002">
        <property type="entry name" value="DUF7580"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029498">
        <property type="entry name" value="HeLo_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542:SF1">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24476">
        <property type="entry name" value="DUF7580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14479">
        <property type="entry name" value="HeLo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="260"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="559" mass="61954" checksum="4DEE9EA5751863CE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBS1</accession>
    <name>X0CBS1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_05876</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBS1"/>
    <dbReference type="eggNOG" id="KOG0908">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1503488_0_0_1"/>
    <dbReference type="OrthoDB" id="19690at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="39"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK91860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="179" mass="20089" checksum="0A3449FC04B1F4D1" modified="2014-05-14" version="1">MRKRRQRENRDINTSQPQQRQDYSHQLPKLNRLSSHRISKLSSKTLPISVDQYQQKNKMVHHITSNDELQKLLSSTTYVAVDFFADWCPPCKAIAPVYEQLATKHSVDNVLAFAKVNVDHVQDAARQYGITAMPTFLFFKEGKQVAVNGQVEIKGADPRSLGAAAEKLGGLAQKRVSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCS0</accession>
    <name>X0CCS0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anaphase spindle elongation protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCS0"/>
    <dbReference type="eggNOG" id="KOG4302">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013892_0_0_1"/>
    <dbReference type="OrthoDB" id="642895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990023">
        <property type="term" value="C:mitotic spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051256">
        <property type="term" value="P:mitotic spindle midzone assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007145">
        <property type="entry name" value="MAP65_Ase1_PRC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19321:SF41">
        <property type="entry name" value="FASCETTO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19321">
        <property type="entry name" value="PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03999">
        <property type="entry name" value="MAP65_ASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="383"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="225"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="568"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="579"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="607"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="632"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="678"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="695"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="772" mass="87506" checksum="08FF21955078873E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD97</accession>
    <name>X0CD97_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658439">
        <property type="protein sequence ID" value="EXK80632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD97"/>
    <dbReference type="HOGENOM" id="CLU_048775_0_0_1"/>
    <dbReference type="OrthoDB" id="5081174at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939312" description="Peptidase A1 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="43884" checksum="0120A5BD1D3F46B9" modified="2014-05-14" version="1">MQQRLVRRLFWAFTYLSWIAAAGPYSGYDVSALIPFDDQTNPTWTKHVHVKMKVGSTSGDMLRLWIDTGSTGVVLPGKDIAGFSQNDCTWRNRGFHYLTSSNILYLGCWITKDLYFFNTETTENLVVQSRVPILAVYRRIECDASTDDLYVFSHGDCPDKVSDVLDPSGFGFIGIGWGRMDDGQPDGTSDKNPMINVVNIAGAASTSTLYKGFIIKKEGIQVGLTEANTVGIDFVDLPLHKPPPSGGGSGSSGTPNWGQIPACIWFGSEDPRTDSCQEVSALLDTGIAQSYFRIPTTSGHLPPRVDPTSGDIRVVTNTPVTVSFKPSVSGWLFGLNPSESFKVGVFSGGLHDVTPKEMRAYRKGGYVVATFFNSGMHIFRKYEITHDAQRGRVGFKRWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDE4</accession>
    <name>X0CDE4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Protoporphyrinogen oxidase</fullName>
            <ecNumber evidence="4 11">1.3.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_07896</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:25576"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.4" evidence="4 11"/>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDE4"/>
    <dbReference type="eggNOG" id="KOG1276">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009629_1_0_1"/>
    <dbReference type="OrthoDB" id="438553at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF3">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="12">
        <location>
            <begin position="78"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK89228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="595" mass="65140" checksum="72BCE40BAF4A9804" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDF1</accession>
    <name>X0CDF1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_06089</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDF1"/>
    <dbReference type="eggNOG" id="ENOG502QWTJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008241_0_0_1"/>
    <dbReference type="OrthoDB" id="2563500at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF7">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="104"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="143"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="680"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="721"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="680"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="773"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK92191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="832" mass="92321" checksum="D796532DE81A7800" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE88</accession>
    <name>X0CE88_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Siderophore iron transporter mirB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_05634</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE88"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012970_1_0_1"/>
    <dbReference type="OrthoDB" id="4078873at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF107">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="548"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK92516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="64800" checksum="E3A33A5077BFE517" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CED6</accession>
    <name>X0CED6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK81002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CED6"/>
    <dbReference type="HOGENOM" id="CLU_1332034_0_0_1"/>
    <dbReference type="OrthoDB" id="5100925at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939331" description="Apple domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="22084" checksum="10B41B16FAB060B2" modified="2014-05-14" version="1">MIFPNSLAVAFVAFAGVNAGPCRPSSSATSSEATTTITSNVESVATASTSVQDTTETTTATSAESDVSTTIILSVSETSTAIESDTTTLFTATSQDLPTTITTTTAAMITYEAPDAPAPQCADLDNPYFADDEIEYELYCNWRFDGYEDIGYQQDSTMEKCIMACGQLGACNYAQFETENSLCILIATGFDYSSNKPGFAVAARQRPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF54</accession>
    <name>X0CF54_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="9">1.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_07563</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-proline + NADP(+) = (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="9"/>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF54"/>
    <dbReference type="eggNOG" id="KOG3124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042344_0_1_1"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000105">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="10">
        <location>
            <begin position="9"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="11">
        <location>
            <begin position="174"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="73"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK89464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="281" mass="29365" checksum="755C6262D71F1053" modified="2014-05-14" version="1">MTPSLQDAKITFLGGGNMAAAIIGGLLAKNISKSNIYVSEPWDVNRNKMADLGVKTTADNKEAAADADVLILAVKPQVAKGVCEELSSAWAKRDSLPVVISIAAGITLESIAQWFKGDAGKAPHIVRVMPNTPALVGEGASGLYAADDVTKEERELTSALLGSVSKATEWVDKEELLDVVTGISGSGPAYFFAFVEHLISSGIGLGLSEEQATRLATQTCLGAGKMLVESSDEPSQLRKNVTSPNGTTHAALVSFENSGLKEIVDKAVKAAADRAKELGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFI3</accession>
    <name>X0CFI3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979333">
        <property type="protein sequence ID" value="EXK81377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFI3"/>
    <dbReference type="HOGENOM" id="CLU_3032402_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="55" mass="6465" checksum="A23BFE3503C0DCC4" modified="2014-05-14" version="1">MIDLQPPIDFAEVSGQRAKTEHKRYARLAADFVYFRHEERRNEEQLNIDLAGYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFZ9</accession>
    <name>X0CFZ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Pisatin demethylase / cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_05462</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFZ9"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK93335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="59515" checksum="2CE5B85871F63C64" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGG6</accession>
    <name>X0CGG6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_05411</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGG6"/>
    <dbReference type="eggNOG" id="KOG2246">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF43">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="12">
        <location>
            <begin position="189"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK93266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="504" mass="58436" checksum="9928BD811268B61F" modified="2014-05-14" version="1">MPSSWSSSSRRLMLNKRFSRMAIAGLCTVVFLILVFWGAIHGSYGVSQYYSFSTTSSFRPVSVDPEGKTTQDLCATFPKHLLQTIQPVLKMGHADTKERLDAQFDSVSACFGKDELLVISDLDESVHDHQAIDVLADLPAIYYHDNPDFVNYMWQKEMRANGTLDVDLEATARIQGWRMDKFKFLPMIERAWKMKPNKDFYFFFETDTYVFWDNAFRFLQTFDPDAPLYMGSPSPGTHDVKQDIKTWFANGGPGFVLSRGAMRALLVRKTTPYGQYVEPPATEKWLPMLRDDCCGDSVTGWALWNVSVPLRGYWPLFNPHPLHSIPFSDKYWCQPVMTLHKSSPKDMVDVWRWEFAQRQLGRPLLYSDVWKFHHPGDREVAENWDNGKWDFTVAPPEAKIDSFEACGKYCKDSSDCLQYNWRGRDEKKCVTSKSFRVGEPRQPEKIIEPEVKDDKGNVIPPPPDRQDRWVDFKSGWLTERIEQWRSNRNCSEVQWVGPSTKRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHD1</accession>
    <name>X0CHD1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHD1"/>
    <dbReference type="eggNOG" id="ENOG502RKP5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066904_0_0_1"/>
    <dbReference type="OrthoDB" id="4939498at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1160">
        <property type="entry name" value="Vasodilator-stimulated phosphoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="385"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="256"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="421" mass="48217" checksum="1E29FEE143D7B231" modified="2014-05-14" version="1">MPLHQRTSASPSKRSSSSVRSTVSARSTNSSSSSKSRALTVQDHDYEYEFDIESELRDDLQKANTELNKANAENDKLSAQNDKLKATIEQLTRKLNESKTSLEETTRKLNESTISCRELKAQIEGVRSEADVLREDNRRLNTDFEELKGDKRRLNNECEELKEEKEALKEENERVKFEHHDLEQRFIGLQAKHENLTMRHNAVSSQAPSSAMTSPMSSPMPSPLPAPLQEGRKNPSRPSSKASSKASSKVSTKSSSKREPREDRHREQEDRHQSEREESSREEHTRERRHREDRERRDRDREDRGRPQRSEKPKDKERFEAKERLSKRFDERPAVAPRQASFIEPWGPGGWSPRYDAPPSDFDAYGHMATGRKAASVVSSGAYSNVPRTTSIVNGHFSSDSSAYDDERYEDGSYHAYPIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHX0</accession>
    <name>X0CHX0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mannan polymerase II complex ANP1 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_06990</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHX0"/>
    <dbReference type="eggNOG" id="ENOG502QVDT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017872_4_2_1"/>
    <dbReference type="OrthoDB" id="204164at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000017">
        <property type="entry name" value="Mannan polymerase II complex ANP1 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF4">
        <property type="entry name" value="N-GLYCOSYL-TRANSFERASE (AFU_ORTHOLOGUE AFUA_4G06870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK90868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="404" mass="46290" checksum="81A79FF5ADB6ACFC" modified="2014-05-14" version="1">MLLPGGGLNWKAAKAQMPPSRVLRSNLTRSRLLLLIGVTGIVMLLYRTFRAPPPGPQNVRCWGPNKSPMEMTPNEHALWNAHMQTPVLFNHHKPLKVESPSIQHIDLNPITSSPQALIRNERVLILTPLKDAAPFLKNYFKLIAELTYPHRLIDLAFLISDSKDDTLAVLASELDHLQKRKDEVPFNSITVVEKNFHFHLSQDAEQRHGFEVQAPRRKAMAKARNYLLATALKPEHSWVYWRDVDIEQAPRRIIEDFVAHDRDILVPNIWFHRFEKGVDIEGRFDYNSWIESDKGRKLANSLPKDTVIVEGYKEFDTGREYMCKMGDWRENKDVEVQLDGIGGVNILVKADVHRSGINFPAYAFENQAETEGFAKMAKRAGYQVIGLPNYIVWHYDTQEKGGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CI62</accession>
    <name>X0CI62_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CI62"/>
    <dbReference type="eggNOG" id="ENOG502S4MP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041458_1_0_1"/>
    <dbReference type="OrthoDB" id="3886346at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="389" mass="43249" checksum="795B5877154108FA" modified="2014-05-14" version="1">MAMDALKNLVNNVPDWLQRLDDLSGQIDRRQAELAAVAAAEGKSAETKSLRNKGSTESLKPKDDPPVVHAEVPANEDILEDGAGDNTAQTPVKPETPKVHTPSPGSIRQQQEIIKAAQARARAQVRKKPKSPSMMSNEDAPAAYRTRSMIIVYYDSYVQSFFDDLVRFVSSSRNLMRKAKMAARVAQIKKLAEQDVSEDGSNDDALPSLRYMSSRRFGPMSISRPGAGDQPPDVYDKLDKGLEFVQSMCEHGAHQFLRDGDCNDEISKVQKRLTEVLEMAKTEMERVEREEPELAKETGEMGKVRTRRPISMRRDMAVGLKESSPTPTKEENKLEPAKLEAAEPIIAADPMAPMAVDPNIMEADEGIDVEMELPKLQYRSTRAMRSRGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIC3</accession>
    <name>X0CIC3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">GPI inositol-deacylase</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_06557</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIC3"/>
    <dbReference type="eggNOG" id="ENOG502QQNH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015737_0_0_1"/>
    <dbReference type="OrthoDB" id="5592486at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GPI inositol-deacylase PGAP1-like alpha/beta" evidence="4">
        <location>
            <begin position="131"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK91028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="330" mass="36691" checksum="83193D345CAF5CDB" modified="2014-05-14" version="1">MNKSAIWRNAPASPLSRQLYRAQCHRSFACSTYLGREHDPRIKALGREISDDYAIIREKYETPKYPIVLAHGLFGFAELRLSPYFPAVEYWHGIRDALTAQGATVLTPTVPPSSSIADRATALRSALEALAPMPEAVTIVAHSMGGLDTRYMLSHLAPLPVRVAAVVTVATPHRGSAFADYLLDEEVSPLHHYLPQLYQTFEKAGLGTAAFSQLTRRYMAEEFNPSTPDQPDVRYFSYGAAVERPALLSPFRHPHAVMTQAEGPNDGLVSVESSHWGTYKGTLLGVSHLDLINWSNRVGWTVREWMGIKKNFNAIAFYLDIADMLAKEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIQ0</accession>
    <name>X0CIQ0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIQ0"/>
    <dbReference type="HOGENOM" id="CLU_1098557_0_0_1"/>
    <dbReference type="OrthoDB" id="5428040at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="253" mass="28742" checksum="146D7B3BE0F4D9E7" modified="2014-05-14" version="1">MAIPSEPTVEWQRNGPWKSSQQLRKQLGIGVFNKDYRRRHIMQLEIGVHDSKYSKSMAEYKNFALEQALLGYPPQGGWAMTNYKDLYEEDWIAWWAAHAVHVSLIQDILRATGDPALAIQALAFRFHSMIFYDSMADFDLQKPVTTINSAEMLLPVRWKGLAVVLGLALVHLLLLCSTMVLFQFKTRASSLGNAWQATAQVVSTETRAVVEEASAVRDKEVEAWARSSGVSRRSYTVMMSDVRNRTEIVDQKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJB7</accession>
    <name>X0CJB7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6594 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJB7"/>
    <dbReference type="OrthoDB" id="5342093at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046529">
        <property type="entry name" value="DUF6594"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502:SF4">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20237">
        <property type="entry name" value="DUF6594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6594" evidence="2">
        <location>
            <begin position="58"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="335" mass="37196" checksum="984613320B3D8957" modified="2014-05-14" version="1">MPGHQTSYLYSPSSCHSFPDMVSECFGIFSNNNGAASETADVEKHGGQDIQQGPLGFAALSSLMASDGDQELLIFRRFDDISARNLLYLQCELLSIEDRLKKWDRNVLRSRNTKLEEIAYRWEEMVKQAKEGKDEAKEMMELVYQLRSKIKEYHEALELQSRVARLHPPDKRALKVARNELWGGPLETDGLKPSPIVGGRAKDYLDRESDLVSVKAPVETDLLSKTLRAVWPGKEETSRDGLSRISRFDERSVAITVATINIIFAIILLVGPITSLSYVSSRAAVLGMICTFTALFAISLGLMTKAKRAEIFAGSAAYTAVLMVYVSNGDFSSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJC0</accession>
    <name>X0CJC0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">SHO1 osmosensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_04576</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Forms homooligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJC0"/>
    <dbReference type="eggNOG" id="ENOG502QW7A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043316_1_0_1"/>
    <dbReference type="OrthoDB" id="5983572at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007232">
        <property type="term" value="P:osmosensory signaling pathway via Sho1 osmosensor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11855">
        <property type="entry name" value="SH3_Sho1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000213">
        <property type="entry name" value="High osmolarity signaling protein SHO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035522">
        <property type="entry name" value="Sho1_SH3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="264"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK94530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="323" mass="35035" checksum="D127642A31591ECB" modified="2014-05-14" version="1">MPSYSLNSPSLQKMDHSRMYGQRKGIQMSNILGDPFALATLSISTLAWFITFVSCIIGRIQQNSDADLAKNDPFPTFVWWSCIYCLCLIVGVFVVIGSDAVHTYHVAVTGYLAAGIVLVSSGINQLLYSNSGAREAASAGFILLAMVIVIWTFYFGSSPSSTPRAFLDSFALAKESTTIHRSTMNAYGGRPETSNSVQPPQMYTSAQLNGFENPSPVGGISQVGGARGSAVPQSFTNSVMQQQPPQAKPNNSPGNDTEVVPPTEYPYRAKAIYSYEANPDDANEISFSKHEILEVSDVSGRWWQARKESGETGIAPSNYLILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJZ8</accession>
    <name>X0CJZ8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Membrane protein TMS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_06333</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TDE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJZ8"/>
    <dbReference type="eggNOG" id="KOG2592">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029574_2_0_1"/>
    <dbReference type="OrthoDB" id="5963193at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005016">
        <property type="entry name" value="TDE1/TMS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383">
        <property type="entry name" value="SERINE INCORPORATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383:SF9">
        <property type="entry name" value="SERINE INCORPORATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03348">
        <property type="entry name" value="Serinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937245" description="Membrane protein TMS1" evidence="7">
        <location>
            <begin position="20"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK91613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="475" mass="51568" checksum="FCECC2581B78BD69" modified="2014-05-14" version="1">MGALLSLPLLAVPSIGTIASFAASCCGAATCSMVCSACGKCGNSIATRIAYALLLLVNSIIAWIMLTPWAIKKLQKLTLDYVTINCPTGECHGWFAVHRINFALGLFHLILAGLLFGVATSKNPRAAIQNGYWGPKVIAWLAFVVLSFLIPDNFFLFWGNYIAFAAAMLFLLLGLILLVDLAHNWAEYCLAQIEDTDSRVWRFVLIGSTLGMYIGSLAMTIVQYIFFARGSCSMNQAVITINLILWLGISVISVNPTVQEFNPKAGLAQAAMVAVYCTYLTMSAVSMEPNNECNPLIQGQGTRATSIVIGAIVTLLTIAYTTTRAATQSLGLGNSNGIQLPDDDEHGLVTQQPSARREMRAEALRRAVEEGSLPADALLSDDESEAGDAPAGDDERNRTQYSYSVFHIIFFLATAWVATLLTMNFDESTKDGDFATVGRTYAASWVKIVSAWVCYGMYTWTLVAPVVLPDRFDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN43</accession>
    <name>X0CN43_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05746</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN43"/>
    <dbReference type="SMR" id="X0CN43"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903475">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="9"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK92693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="147" mass="16377" checksum="344388292154EB2C" modified="2014-05-14" version="1">MSSNKFDSQASTNYKEAFALFDKRGNGRVTVDSLGDLLRACGQNPTLAEIQDLEKNVGGEFDFETFQRVLNRPGGFRDPGEPEEYCRGFQVFDKDMTGFIGVGQLKYILTNLGEKMTDEEVDELLKAVDTSSGQVNYTDLVRTILAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPW5</accession>
    <name>X0CPW5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPW5"/>
    <dbReference type="eggNOG" id="ENOG502QU7D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_398504_0_0_1"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="769" mass="88066" checksum="C4C8816FFEF1B644" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ54</accession>
    <name>X0CQ54_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11167</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ54"/>
    <dbReference type="eggNOG" id="ENOG502TDGS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_2_0_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="30520" checksum="1561F8E66F16E0CD" modified="2014-05-14" version="1">MSRSSLDDLESHESHDRLLKNGDGHLNDSRDWETHIEQSSKQRVPNYMSAIAFTSILLNLLLIISSLCLWARTRSPLPPWPDTLYSPAQSAVEYEIVTFNSDFPEDHSGTTDFYGASPEAEEAWRNLMKPYLVRIPGQEASRLSRPTSQISRDPDYYITSLDVYHQLHCLNDIRKMVRDFNSTEGGLGRLQTMHKFHCIDSIRQSLMCNADLSLIHWYWAPQVGKNFPNATTTHICRKWSLIEEWAMNYRLDQDDYDPRTHID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQR4</accession>
    <name>X0CQR4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQR4"/>
    <dbReference type="HOGENOM" id="CLU_3384770_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="33" mass="3502" checksum="C6ADF9383546F4D7" modified="2014-05-14" version="1">MENDAELLECEPPLKQVVHGHRGLFVIGGGGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTQ6</accession>
    <name>X0CTQ6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">COP9 signalosome complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_04385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M67A family. CSN6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTQ6"/>
    <dbReference type="eggNOG" id="KOG3050">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027018_2_0_1"/>
    <dbReference type="OrthoDB" id="1378at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08063">
        <property type="entry name" value="MPN_CSN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033859">
        <property type="entry name" value="MPN_CSN6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF8">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="MPN" evidence="4">
        <location>
            <begin position="21"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK94244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="418" mass="45818" checksum="07350E77A32473FA" modified="2014-05-14" version="1">MAASTPASPLLSNQKSSELQAVLHPLVLLTISDYITRHTLRQQEGPIIGVLLGQQNGREITVEHAFEAHTRQEPNVQGGYLLDATKFGARLEQMITVHKDRHLDLVGWYTLLPSSGPTPTILPIHNQILEGWNESAILLGFHPEQVLDHSVGGRLPLTIYESNYEVDDPKADNDGEDKKMDDGEPALKLKFRELPYSVETDETEMISMNYVAASGGNAAAAPQKEDKPSLSIESNGKGKRRLVESHDEDHNKAIAQDDEVVLTPEEDETIAALTAKANAIKMLQSRILLLTTYLERLPPSYINGDTADSSSMDADYTTPSATVLRQIQALVSRLDLVIPSDRAAFEREMLHEANDVNLVRLLNGIVQSVGQARDVGKKFHVVENAKASHRRGAPPGPGQDFVIDPAAYNIRGAGDILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV80</accession>
    <name>X0CV80_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV80"/>
    <dbReference type="HOGENOM" id="CLU_1695542_0_0_1"/>
    <dbReference type="OrthoDB" id="5080804at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937981" evidence="1">
        <location>
            <begin position="19"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="156" mass="16684" checksum="31529293AC1AF261" modified="2014-05-14" version="1">MKVTTIASLLLGALPVFASPAAVGDSTRNTVKDLSLTVVEQNSTYVCWTYDYQPGVDLASAADSAALVRRANIRWPGVNERVSVALEYAKVTIIRLAANEIKVIIDNLTQHVVNVLVGWELGDVDDQVPAGATSSTTQRIHQGTSQSISVNAYLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV93</accession>
    <name>X0CV93_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV93"/>
    <dbReference type="HOGENOM" id="CLU_1927685_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="131" mass="14935" checksum="8EDC26C98ECFC169" modified="2014-05-14" version="1">MHPRLAAQRTTTQQKQGTDELPIIEMSEGFRLRPSVAATGTKVYLSGAAPWPLDTRQASLVARNGLPFDIGQCSWCFFGGLLFSYCCWLRFNVLPRRHEFMTPACHRHPFCLVRQKLMLLCDSRAPGYEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-09-13" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CX95</accession>
    <name>X0CX95_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CX95"/>
    <dbReference type="eggNOG" id="ENOG502S8WW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064787_2_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06293">
        <property type="entry name" value="Kdo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="30501" checksum="D0465BE580C14C06" modified="2014-05-14" version="1">MKHNNNVRLLAVLADPESDEKSEYRFLVDGAHVRYVTLDGGLIDPEHRTYEPKLLPQLPVFPPGDWNEGRVGKDGHTGKPFFCETRRSSLPGIGNVWHDVMVDHLELRQIERVRQTLYRVSHPSSKTPVLAKFAQFPWEIPYFAAETTSYEWIHGQGIGPEFLGHIHENGRVIGFLLEEIHNARTAEPEDLAACQRSLQKLHDLGIVHGDINKHNFLIRQDGDAVLIDFETAYKCTDPDILDEEYRHVKESLEDTSGRGGAGMASDSSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXF4</accession>
    <name>X0CXF4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXF4"/>
    <dbReference type="eggNOG" id="ENOG502RWVK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_760865_0_0_1"/>
    <dbReference type="OrthoDB" id="5041041at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="340" mass="38036" checksum="984CEF64840B4281" modified="2014-05-14" version="1">MPDLFTQQVIINCWSVSANDPNLSKRKNKSQNPLQISAILCGRDYGLISKNIVEKLLGTSEKHTSGLPSVVEISWTLSGSEQDLETSQVRVIPGLEQDLVLGDNTEELYQSVHLTPPSHSQGSKPEEHGPSTSCPEALPFQFNTSEDFKSQGIIPKNQQSQEILKQLLGRCRTRAQSPLPHHKTVASEPEQPEGPSKISTDSLCGSFDISSNTSDSDGKWIMPPNDKLHRERTSSLQPSDADSLVDPSEDVAWEVSTEASQALSQSFQFHGWSLVDTASADTHPSTPEWVEDQNITHESQNDDFATHPGHRFWEWDVERQLWRRKGQNGSDERDWFEIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXZ7</accession>
    <name>X0CXZ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein RTA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09163</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXZ7"/>
    <dbReference type="eggNOG" id="ENOG502QURG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033465_3_1_1"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF35">
        <property type="entry name" value="RTA1 DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK87342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33689" checksum="78DFC66360091F8E" modified="2014-05-14" version="1">MAGYIFYNYNPNMVAAVIFIAVFGLSALLHTYQLIRSRTWYFIPFLIGCLFECVGYVGRALSAQEAPDFTKNPYIIQSLLLLLGPALLAASIYMVLGRLIRLLDAGDLSIISPRWLTKVFVAGDVMSFLAQSAGGGMLATAKTKSAVKRGENIIVGGLGIQIIFFGFFMVVTLVFHLRINRNPTQKSQEITTPWKKLLIVLYSASLFIMVRSVFRVAEYVMGKDSELQSKEYFIYIFDALLMSLVVVSLNVFHPSRVINHDKDRKRIVSQDGYALESQPVGGDDRDRRYSLSPVRPKHTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY58</accession>
    <name>X0CY58_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_01984</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY58"/>
    <dbReference type="eggNOG" id="KOG0252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_46_12_1"/>
    <dbReference type="OrthoDB" id="2153661at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000140">
        <property type="entry name" value="Putative MFS phospholipid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="48"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK99460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="506" mass="54753" checksum="048874A2EA27C78D" modified="2014-05-14" version="1">MSALEITSATAGHELDDTKKVKDEDIQDVEIGDVRKPDLYSKVSVYLTMVFSGLALGSDGYNAAVIGNLELLFATLYPEALTSTMRSRLSNAFLIGMIVGMIGFGVVVDQLGRKTGAVMTTLILLLGIAMSAGASGLTSTGLMWMLVIARGVAGVGAGGEYPVSGAGAMEASDEDGQFRKSRGFMFAMVADLSAGLGYTFGALVPLLLLLCVHQRTDRYETVWRVALALGAVPPLSIFWFRLRMRVSTAYRNSALRKQRTPYVLIFKKYWRRIIGAALSWFLYNWISIPFGIFSSVIISRVNASNSLVQNLGWGALINSFYLPGPFIGGYLSDKIGRRKTMALGYTLQAVLGFVLGGANEQIQKVFPLFVVLYGIFLTLGEVGPGSTVVIVATEPFPTSVRGHALGFISAWSKAGAAIGTQVFTAILSSYTDTVKGNQVVFLIGSAFAVLGALNAWFVVQDGEKHLEKEDQIWKDYLLEHGWDASWGDHQTQDPVGTLKDELKPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ31</accession>
    <name>X0CZ31_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03566</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ31"/>
    <dbReference type="HOGENOM" id="CLU_146164_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="150" mass="16784" checksum="630B2B257DD01EA1" modified="2014-05-14" version="1">MDTSPLTWSDKYFPDGESYTSVSHDKGFHAACVEIVGDNLSAKGFLESSTRLHLDAWQHRDSGGPEKEVTLPVFDGQSVWAQYIEIEGRNYFKPLSTIRMNENDTKILVAEPNFSSKMQKSPPVDNITFYLLCLGLSAAHGGSRNRLLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZA8</accession>
    <name>X0CZA8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-fuculose-phosphate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZA8"/>
    <dbReference type="eggNOG" id="KOG3699">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006033_1_2_1"/>
    <dbReference type="OrthoDB" id="3238794at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000009">
        <property type="entry name" value="Class II aldolase/adducin N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF25">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="2">
        <location>
            <begin position="60"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK96638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="298" mass="32806" checksum="41BFB5F87A34D03E" modified="2014-05-14" version="1">MSATTTIQAQSGTLTIAPKPTHGHELKDKTPLQAMSHGDVVLSGIPSHPDFSSQRQWQLEHMAAAFRHWHREGYVEGMSGHISVRDPEFTDAFWTNPLGRHFGLLKVSDMILVNLDGEVIGGNRSRPPNTAGFLIHASIHKARSDVHAICHCHSIHGKAWSVFGKRLEMLTQDVCKFRGDAHSVYDSYGGVVLGSEEGDRIAAAMGPKGKGCILRNHGILTVGQTVDEAAWLYTSMENSCRVQLLAEAAAANGVPKVLIEDEEANFNFDVESDPEICYCEFQVYYDLEDEMSNGAFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZZ0</accession>
    <name>X0CZZ0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_03466</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZZ0"/>
    <dbReference type="eggNOG" id="KOG3904">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018689_0_0_1"/>
    <dbReference type="OrthoDB" id="1695362at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18870">
        <property type="entry name" value="NUDIX_AcylCoAdiphos_Nudt19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039121">
        <property type="entry name" value="NUDT19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12318:SF0">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE NUDT19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12318">
        <property type="entry name" value="TESTOSTERONE-REGULATED PROTEIN RP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="8">
        <location>
            <begin position="56"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="360"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK96434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="387" mass="43593" checksum="2981596891ADF458" modified="2014-05-14" version="1">MSLLFCVTRRSLSRQLFRDTNLTAHRQNFNFVPRVYLPIMTSRNQSSSANKPPPSEPRPSSSVLLVSPVNEVLLLHRVHTSTSFASAHVFPGGNLDPYHDGIIPAEDSPERHHDGLAYRIGAIRETFEETGILLAKKDNELVNLTVEDRDTARKMIHGNQVKFLEWLKSVGAEPDLDGLIPFTRWITPATNTKRFTTQMYLYMLPQSQSDMPSEMLIPTPDNGIEHTAALFAPAESFLARAATNSIILFPPQYFLLSLVARVFQNSKESSDGQRPPQITAQRENLLSFLNRVPTAETEKGQAHKTAMIPWSEKVMSPHNLFIRQQDKRIVLGLDKPGPELRGSERGGDWEHVVLVNFGKGGPTNVEVRRREDALEEERKVKADSEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D184</accession>
    <name>X0D184_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">General RNA polymerase II transcription factor TAF12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502QR8W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_247299_0_0_1"/>
    <dbReference type="OrthoDB" id="3439539at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1471"/>
            <end position="1629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="646"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="787"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="805"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="831"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="902"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="970"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="983"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1127"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1144"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1177"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1239"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1263"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1278"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1330"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1366"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1390"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1413"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1471"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1539"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1573"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1604"/>
            <end position="1613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1629" mass="174763" checksum="0FDBCD698D9DD6F1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2C6</accession>
    <name>X0D2C6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2C6"/>
    <dbReference type="HOGENOM" id="CLU_2359795_0_0_1"/>
    <dbReference type="OrthoDB" id="5050586at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="96" mass="11170" checksum="25EF9B801721C1A9" modified="2014-05-14" version="1">MALSAEAIISIVGTIINLPSCVLAFYHMCKGQKKDHHKDTRDIEQGHKLPQRMTHYSGYHSIWNQHPDYPSPWVSYIVPSRFRGYDRVQRGPAWTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3B7</accession>
    <name>X0D3B7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3B7"/>
    <dbReference type="eggNOG" id="KOG1363">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020031_2_0_1"/>
    <dbReference type="OrthoDB" id="1026733at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UAS" evidence="3">
        <location>
            <begin position="179"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="495"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="359"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="502"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK98068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="518" mass="57971" checksum="5901B3C69FB47D92" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3N7</accession>
    <name>X0D3N7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein FAF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3N7"/>
    <dbReference type="eggNOG" id="ENOG502QVP1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054969_0_0_1"/>
    <dbReference type="OrthoDB" id="5556956at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053030">
        <property type="entry name" value="Ribosomal_biogenesis_FAF1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096:SF1">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL01042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="32827" checksum="BBDA0D0AFC825C43" modified="2014-05-14" version="1">MAILGKRKAEPEPLISEEDAAAIFRRHFEAEFAPLPEAEAAKSKFKKTKHEGNSNDIESEEEEENNDSNGDDGEWGGLSDEDSVTEEEENPTIQVVDHSSKQPPKPAAMSKRELKAFMSSRPPEQTTPKTEQPLSATSSSSNTLPEDAPSLLAQDLELRRLLAESHLLAPTISASGTTIAPKAFATGRTRQKATDLRVQALGSKVSIHKQEKMPMNMRKGIVAAADAREAKRRREAKENGVILERETGKKKGRRDRGRDVAVDRPGVGRLKGAELRLSDKDIKSIEGGRDTFGRRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0D557</accession>
    <name>X0D557_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Regulator of rDNA transcription protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_01505</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D557"/>
    <dbReference type="eggNOG" id="ENOG502QVX4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062645_0_0_1"/>
    <dbReference type="OrthoDB" id="10012223at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005619">
        <property type="term" value="C:ascospore wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005628">
        <property type="term" value="C:prospore membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF2">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK98673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="33918" checksum="35B3E5D68882062C" modified="2014-05-14" version="1">MADTAEVSGADHQQEPAKRNRVVDSVGEKAQEVFKEDYAQAREHVASAAKSRSYLYPIKGIFYFISHRSLWKPFISKLGPLILLSTGVIGGMFFFTYLPQLAVLFFVNGPIAPFSTVLLVLNESTTIINLVSRNYLLQDALLDVFDGTLLARGDTQIVSEGREVKSGADPMQRLGKIIKSPFEKFSPKAIVRYVMYLPLNAIPVVGTVIFILIQGRTRGKGVHGRYFQLKKWSQPKREDWLTKNVGPYTAFGLVATLLEMIPVASMFFTFSNTVGAALWAADIEDKNASMTDGTAPTLRETAKKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0D567</accession>
    <name>X0D567_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Stress-response A/B barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D567"/>
    <dbReference type="eggNOG" id="ENOG502S73V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080664_2_1_1"/>
    <dbReference type="OrthoDB" id="1601230at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044662">
        <property type="entry name" value="HS1/DABB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178:SF10">
        <property type="entry name" value="STRESS-RESPONSE A_B BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="2">
        <location>
            <begin position="3"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK98259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="110" mass="12338" checksum="15DB74E6F24E6969" modified="2014-05-14" version="1">MSITHTVLFQFKDDVDQKDIRKTCDDFLQLKDQCIHPTSNKPYILSLQGGKDNSPEGMQNGITHGFVATFESAEHRDYYVKTDPAHQTFIANVGGLLEKAIVVDFTNGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9R7</accession>
    <name>X0D9R7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EXS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_00521</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9R7"/>
    <dbReference type="eggNOG" id="KOG1162">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024081_2_1_1"/>
    <dbReference type="OrthoDB" id="2159384at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF46">
        <property type="entry name" value="PROTEIN ERD1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="6">
        <location>
            <begin position="190"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXL00294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="405" mass="46014" checksum="D3683044975B761D" modified="2014-05-14" version="1">MDGDPAVDPGLDSFSLAFPLPYRVGFIATLAVWGWGLNLHCLYLFNVDVPQLIRYPGRASPQHIPHHGSTYRLAIALSALFALSVSLFWVCTWGIPERVVAFGWMPLTYLTALIAMFVVPLRNLPSGGRRRFLATLRRVSLGGLAEPQDGKFGDILLADVLTSYAKVFGDLFITLCMFFSAEGSSTQRPDRNCGGTVLVPFIMGVPSLIRFRQCLIEYFRVRRAPYKESTGWGGQHLANALKYSTAFPVLITSAWQRSTEDPGSKAALHKAWLVAVLINSLYSFYWDVAKDWDMTLFSPKQDRESPTHPFGLRDRLVFRYPNLYYLVIGMDLMLRCTWSMKLNGRLDRFSDLEGGIFLIEFLEVFRRWVWIFFRVETEWLRNNSSGLGVDDILLGDYQGKDNEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0DAV0</accession>
    <name>X0DAV0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="10">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_06373</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="10"/>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DAV0"/>
    <dbReference type="eggNOG" id="KOG0787">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023861_4_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF20">
        <property type="entry name" value="[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="298"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="331"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK91687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="481" mass="52966" checksum="87E286B2B1856000" modified="2014-05-14" version="1">MIASSTRLIRRRGPAASTILRSWPCHTSYRCLSQWRGPRQSHWSHGSTRSRLVTRRSLHSPKVSDDEIATLARQHQHPLCLADLVRHGRPPLSSKSLLSSANFALSLLPVRLAHRIQALRNLPYIVVANPNISRIYNNYLHSLSILLPYWHATREGRPISTLEDEIRFTNVLAELVATHTDTIPILAKGFLECRRYISPEEVTKFLDQHLRARIGTRLIAEQHIALHFSSQPHFDPDASPTPCPDDPSYIGVIDTALRPAQIVESCAGFVADICELRYGVRPLLYIHGEPDTTFAFVPMHLEYIVTELLKNAFRATIENKSNEPVIVTIAPEPALTEEPSTTSWSNSSTKDSDLPSKDSRNATNNDAIVPLDDNAPGVTIRIRDRGGGIPPEVSPNIWSYSFTTFSDDMDDFPGDGNGGDGLSAISTASTGGSSIAGLGYGLPLSRAYAEYFGGGIAVQSLYGWGTDVYLRLKGVGNLGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0DDG5</accession>
    <name>X0DDG5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_00985</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DDG5"/>
    <dbReference type="eggNOG" id="KOG0616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_3_1"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF153">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="259"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="515"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="178"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXL01145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="571" mass="64217" checksum="B3F7DD6922A39A07" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DLQ3</accession>
    <name>X0DLQ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DLQ3"/>
    <dbReference type="HOGENOM" id="CLU_1454495_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="186" mass="20228" checksum="F89E6704595B98E9" modified="2014-05-14" version="1">MNLNQSQGDQHGFVLRTAISGGPGPGPERRTKERTPSTSTPLTLNGYSRAEQLVRGISCQSAVHAMYQTVGTRYFLTSKTQNGSVEKMQRHLWECFSASICYCWNLSGATVKPTNRIPQGGCIRKRLLPLIAPVERFLTASARGAKDSLNPFKPRTAIAQRATLLAIAGCLAAHKASTTANLKLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0DNQ2</accession>
    <name>X0DNQ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_03175</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DNQ2"/>
    <dbReference type="eggNOG" id="ENOG502QRKD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028484_1_0_1"/>
    <dbReference type="OrthoDB" id="17415at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12710:FF:000002">
        <property type="entry name" value="Protein arginine methyltransferase NDUFAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF5">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK95967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="504" mass="58620" checksum="96A5EE601151A0C4" modified="2014-05-14" version="1">MDSPIVAQIFRQLFHHRPPGCKGVRNLAGLRNGLRTTIVSHQSRFYVAGRPSSDRGMKKNESRWQQRTNILPQDRSAEFAEYPYISIDELKQRTERPRKVKMLLRDFIDDSLYNPSYGYFSKQAVIFSPGEPFDFNSMRDEIEFQAELGRRYTEFEDILDEREGENPTRQLWHTPTELFRPYYGEAIARYLVTNYRLTTYPYHDLLIYEMGAGRGTLMLNILDYIREVDPQVYARTKFNIIEISSTLAALQNRHLLSTAASRGHADKVEIINRSIFDWDQYVPSPCFFLAMEVFDNFSHDGIRYDVATEQPLQGHVLIDGDGDFYEFYAHELDPLAARYFRVRHAATGGNYPKPYPSNAVLRYLSTKMPFAANLSDPEFVPTRLMQFFDVLEKYFPGHRLVTSDFDWLPQAVKGMNAPVVQTRYHRKMVPVTTPLVHQGYFDILFPTDFRVTEAIYRAITGKLTRVMSHGDFMRKWAYVEDTETRSGENPLISNYRNASVLVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0B235</accession>
    <name>X0B235_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979805">
        <property type="protein sequence ID" value="EXK75806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B235"/>
    <dbReference type="eggNOG" id="ENOG502RYIG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093911_0_0_1"/>
    <dbReference type="OrthoDB" id="3524154at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057026">
        <property type="entry name" value="Znf-C2H2_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24537">
        <property type="entry name" value="zf-C2H2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK75806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="251" mass="28343" checksum="92D834D1BF727BBD" modified="2014-05-14" version="1">MPPVHTSRSNSYISTMSMSVHPAGLATANSFGRQLNPIPRTSTSGCKLILPQTISDASTRTVTEVKKPGGTRMQSFYMCECCPKKPKRFEAIEDLDAHEAEKQYKCSFCGNRFKAKNEAERHENSLHVRRHSWSCSALSEYDKAFQESTNRPGEADICGYCGDEFPRSGCVPGTGTLSGGNAPRQATDQDWDERIRHLEEIHKFRECNSSKKFFRADHFRQHLKHSHASTSGKWTTMLENDCMLDEDTTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAN2</accession>
    <name>X0BAN2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_16525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658500">
        <property type="protein sequence ID" value="EXK78826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAN2"/>
    <dbReference type="eggNOG" id="KOG3178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_5_0_1"/>
    <dbReference type="OrthoDB" id="3340390at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF17">
        <property type="entry name" value="O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="169"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK78826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="392" mass="43976" checksum="4C2ED4B564A27EF2" modified="2014-05-14" version="1">MPPENNLIEALQCLDDKSFNNEAGRLRALEALTLAVSKIQRPWDIVWQHCWVNPATTACTKTLIDAGVFTKWVEAGGGDKTCVELAELTKTDPVLIRRLIRQISGQNLVIEAAEDTYKPTPWVKALAADQALANVYGGLYHFVNVPMFRTLPEYLKQVGYRNPTDSYNCNWQFVNGSKENVFESLVANPVAAREFNDAMESHSKYNLTPWPEIYPTGTLFANYKLDRPLVVDVGGSKGHDLIKFHIRHPGTPAGSLVLQDLPGILSELDIPDIIYVKPHDFLTPQPVRGARAYFMHNILHDWEDNKASQILKHIADAMEPGYSKLLIHESIMNSIKPLARVTTSDITMMACLGAKERTENEWRQLLQSVGLKVLKIWGPFVSMEGIIESELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBG1</accession>
    <name>X0BBG1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979793">
        <property type="protein sequence ID" value="EXK75819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBG1"/>
    <dbReference type="HOGENOM" id="CLU_1156438_0_0_1"/>
    <dbReference type="OrthoDB" id="5571888at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF77">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="63"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="240" mass="27632" checksum="B0468F512E9AFE4F" modified="2014-05-14" version="1">MEDWPRADLKTPAGVSAVYKDLTPLNPVQEEIRVIHLEGGVDSSPIKCTLQKVELNSTPPPIYDALSYTWGDATDTREIILNGYVVDITFNLFQALRRLRQGVDNQIIWVDAVCINQLDLDERSQQVELMRKVYSLCVQAVIWLGEPPDQATPTFATHWFGDERDNENIDWLWDNFYDYATDPDLDSMDEQTVDWTFHGLANLRLLTSGHLSEHPLFVKLFGDDFEWELIERHDGFDTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBY1</accession>
    <name>X0BBY1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979349">
        <property type="protein sequence ID" value="EXK79291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBY1"/>
    <dbReference type="eggNOG" id="ENOG502RMA6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126662_0_0_1"/>
    <dbReference type="OrthoDB" id="5080010at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="183" mass="20801" checksum="583D4B2628D82DB9" modified="2014-05-14" version="1">MPVMSQDVVEYYYKGHRLADSIEDWAEEVSSATEEMEFVEPTKPQAKMPRIGDPSKEIQIAILLERHNEAREIMKLIEEQLLKLGCEIPQGAISKSSSSKHGGLNHQGGPHREYFTEDSEAQGLLSQDTWAYIPLDSASEGSREKKKKRSKRPKTEEEKSRHINKVFIRENGILPLLDPSSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCA2</accession>
    <name>X0BCA2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tyrosinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_15652</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658460">
        <property type="protein sequence ID" value="EXK79775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCA2"/>
    <dbReference type="HOGENOM" id="CLU_035914_0_1_1"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005717853" evidence="3">
        <location>
            <begin position="21"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK79775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="387" mass="42513" checksum="2F46623FFEBE9FA2" modified="2014-05-14" version="1">MQISFGILAALLGASWLVAAAPAEPSASDLVLDLNGQAMFALENAEAQPSKRSGRKICTIANAAVRRDWKTLSKKEKKAYINAVLCLRKKPSKADPAFAPGARTRYDDFVAVHINQTLSIHGTGNFFTWHRYFTWAYEKALRDECGYKGTQPYWNWFETGDFATNPVFDGSETSMSGDGKYVKHNGALSGMQNIYIPSGSGGGCIKTGPFVGAVANLGPPSPGMDGMEATTTPLEYNPRCLRRDLSHYAIDRWMTLPNLYNITLGDASHSIKAMQDEFQGRFADEFLGIHAAGHFVMGGDSSDLFSSPNDPIFFLHHSMVDRIYWIWQALHPKQAKDIAGTITILNMPPSRDTVKSDPLNMGVNARQITIGHALDTLGGSPFCYIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCF1</accession>
    <name>X0BCF1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979496">
        <property type="protein sequence ID" value="EXK76503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCF1"/>
    <dbReference type="HOGENOM" id="CLU_172691_0_0_1"/>
    <dbReference type="OrthoDB" id="5107907at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="119" mass="13528" checksum="71DB804D3D508F66" modified="2014-05-14" version="1">MSDKDQKKSKEELKKQFAQEVENAESKGMTVGFACSKHKHFYYNETIPTSIYKLTCHMMSCKECLGHLTFIPVVLGRAKGFKDGYGVNAVETRNKSGEFVEGEGGEWKEYLKEVYSKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCH8</accession>
    <name>X0BCH8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979581">
        <property type="protein sequence ID" value="EXK76164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCH8"/>
    <dbReference type="HOGENOM" id="CLU_2644656_0_0_1"/>
    <dbReference type="OrthoDB" id="5062167at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="77" mass="8772" checksum="4D616FA6AE010E01" modified="2014-05-14" version="1" fragment="single">PKTVVKQLEEAAVGALPPNPTIENLPKITWKNRRFTQEDLLTRKGAKGRKSWMKSHGTFLVKLNYQDLPIGHVWCCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD69</accession>
    <name>X0BD69_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979506">
        <property type="protein sequence ID" value="EXK76444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD69"/>
    <dbReference type="HOGENOM" id="CLU_096858_0_0_1"/>
    <dbReference type="OrthoDB" id="5105172at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="176" mass="19537" checksum="CE4BCE7CEC6F40B5" modified="2014-05-14" version="1">MAGRVTKSQHPKTKEGSKLSEYIAIYRDRTMPCSRCFRQKLPCVTKGDQSSCCGNCVDAKEICDGAGVASYLTRNMKECKKLEKYEQEAEEALEKAMARLAWIRKMKRRLKQQGDELFARGMQSLEDAEDSAAVQAESLAISDVQSLGAVDLTDWASIFADVPSVVDENSSPVSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDT4</accession>
    <name>X0BDT4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18293</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658657">
        <property type="protein sequence ID" value="EXK76983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDT4"/>
    <dbReference type="HOGENOM" id="CLU_056399_1_0_1"/>
    <dbReference type="OrthoDB" id="10288519at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="8"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="352" mass="40193" checksum="0494F89F36846010" modified="2014-05-14" version="1">MKRAFDGEVVTFYVGKQKKKFFIHKKLLIETTDTLRVALNGTFTEAATLEMNWPDDDELTFCCYRNFLYHGDYDMPEGLDVCRIAATHLPPASIPLGPTSDNSTLGNGDTDAPGKDEITHVNPEEDPITIPNSPKDLPPSPSIERSAVKDVQSPSAQPISFPRSLNAFLSHEPLNERTGEKRKRPTEGAALLAVKAFQELWPCKNFFDDITWVASEQDDADVFRDSDLLINARVYILADRNICKPLIHISLYHLKVALRCYVLENITSLMEVVRVLYESTQQNDPARILISAYIGCFYERIRHLEPFEEVYLKEADFRHDLQNWLDLRLAGGEEGFEVFNRQHEQRCMLALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDZ5</accession>
    <name>X0BDZ5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histidinol dehydrogenase</fullName>
            <shortName evidence="6">HDH</shortName>
            <ecNumber evidence="6">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_15397</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 11">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="6"/>
    <dbReference type="EMBL" id="KI979341">
        <property type="protein sequence ID" value="EXK80046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDZ5"/>
    <dbReference type="eggNOG" id="KOG2697">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006732_3_3_1"/>
    <dbReference type="OrthoDB" id="1703565at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000001">
        <property type="entry name" value="Histidinol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000026">
        <property type="entry name" value="Histidinol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF14">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK80046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="438" mass="47239" checksum="90DD427DD34FB9E1" modified="2014-05-14" version="1">MARTHLKRPASANSTNKATNGSLPDVPRIVKEVIDSIRREGDAAVQRYSEQFDNWSPSNFKLCKEDIDQVMAQVPEQVINDIKAVQSNVRKFAEAQLNSIQEFELEMAPGVFLGQKNNPIDSVGAYIPGGRYPLLASAHMTILTAKVAGVRNVVACTPPAAGEIPLATVAAMHLAGADEIFILGGIQAIAAMAIGTETVPKVDFIAGPGNAFVAEAKRQLFGQIGIDLFAGPTEVLIVADETADPYMIATDLLSQAEHGPDTPAVLICTSAEVAKRAIEYCDEQLTTLKTAAVASVSWRDYGEVILADTVDEAYQIADEFASEHVQILTASPRDALIKMQHYGALFLGPMTCVSFGDKCIGTNHVLPTKHAARYTGGLWVGKFLRTVTYQEVKSAQASGELGQLCGRAARVELFEGHARSGDIRAHRYVGDKFEWIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF64</accession>
    <name>X0BF64_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Sexual differentiation process protein isp4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_18171</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979416">
        <property type="protein sequence ID" value="EXK77119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF64"/>
    <dbReference type="HOGENOM" id="CLU_004965_5_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK77119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="35381" checksum="89FB2855C43EF6D3" modified="2014-05-14" version="1">MFLIMLALAFITCLVWDSQLPWWALVLSLIIPAVWIVPIGMIQAISNIQLGLSVITEFIIGYLRPGRPLGMMLFKSYGYIAMFQGLAFTQDLKVGHYMKVPPKALFWAQTVATFWGSLVQVAVYGWAVNAIPNICEVHQANKFTCPYGNTFFASSVVWGLIGPARIFNPGMIYNSVLWFFLLGLLLPVAVFACSKVWPMSSFFKNINTSLLIGGSGYIPPGTPLSYLSWGAVGFVFNNLIKNRRRGWWMQYNYITSAGLDIGLAICTILIFFAIQLTNTKVPQWWGNVDVFNTLDASVDLNVQKTVTPGETFGPQSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFG7</accession>
    <name>X0BFG7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7732 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658434">
        <property type="protein sequence ID" value="EXK80890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFG7"/>
    <dbReference type="HOGENOM" id="CLU_060392_1_0_1"/>
    <dbReference type="OrthoDB" id="5425547at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056634">
        <property type="entry name" value="DUF7732"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42091">
        <property type="entry name" value="CONSERVED GLYCINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_7G02440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42091:SF1">
        <property type="entry name" value="CONSERVED GLYCINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_7G02440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24866">
        <property type="entry name" value="DUF7732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7732" evidence="2">
        <location>
            <begin position="64"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="218" mass="22935" checksum="BC3BCE7369805C1C" modified="2014-05-14" version="1">MSTITDSLNPKRIGSEPRAETHLLDKRRGSSHGGGRGGTKGSGSKSSQGSPGVGPQPTFADGRYYAGGSVRPFKAGAASPGGIRPYAMAGAALSFWPGVWLYGAYMYPFTDTCSYHNETSDEDEERPVLCGCSRYENCACDDPDSAPYFKELIGSGSYEALNKSIVDVAVVNGTKSILINGTLPNDTALASDKDKNSAPTRCVVGTFGYWPTVAVVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFV4</accession>
    <name>X0BFV4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658581">
        <property type="protein sequence ID" value="EXK77708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFV4"/>
    <dbReference type="HOGENOM" id="CLU_1749744_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="149" mass="15922" checksum="356DFAD4E863037D" modified="2014-05-14" version="1">MSPVEFGPSMDRGLSLGVVDGTHFPGVVLLLRYKAQEADDEALSSKAEEIKMSEDKDEPVVIDEHPKDHDDAAISVSTGSPHLSPKSIDSTAETNEKQQVPPVSGGPPPINIKEDPLPIHPRPAYDSAGECTPRTRTSSCAPSWKAANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGK3</accession>
    <name>X0BGK3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658554">
        <property type="protein sequence ID" value="EXK77978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGK3"/>
    <dbReference type="HOGENOM" id="CLU_043687_1_0_1"/>
    <dbReference type="OrthoDB" id="5086500at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046536">
        <property type="entry name" value="DUF6601"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414:SF1">
        <property type="entry name" value="SUBTILISIN-LIKE SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20246">
        <property type="entry name" value="DUF6601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="357" mass="40601" checksum="9DF44BAA146ED2BB" modified="2014-05-14" version="1">MADPVNDAPFQNKDALNAERLLDPSDHSTRSNPWLTTFHPTPQNETKSINHVPGEPTISLSESGTFLQKELATPVLDELYRNLRWFAKQSSSNIDALHRQIIKGRNIVPTEESRLHLIWQEKRIFIKPIPLCLFNHDFWKYFLRSNLNTTSRLSSATGSNVVSEQSPASGPYRAAALGFLRSYAFLIQHRSDLGLAKEHHLIPKDVDWVQWSKFIAGFRKLTDNDVAKRYRYGQLRLTGLNWVTRIFRPKSAATYWFYEEAHWSTVPYIREAAVPLAFIFASVSLILSSMQVMLALCSDSQFSKGVNKGHLEAVQLTSWRFSIAVLLFSGLCLALLALIPLIVIICQLFWGGLQEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH87</accession>
    <name>X0BH87_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658426">
        <property type="protein sequence ID" value="EXK81540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH87"/>
    <dbReference type="HOGENOM" id="CLU_039184_0_0_1"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="34151" checksum="BE08C0ACC30B2A8C" modified="2014-05-14" version="1">MHPGSLLSSLLSYVPMSDPKCSYKFTFEPGWFVDYPVISHSCPGSKLTTQPNLGLPDDREWTRLTEHVERLNHQDNSDIIHKILLVARHGHGVHNDVMEEVGSEEWKNHWSKLPGDANRTWLDAELVEKGVEQATDLGKMYAEGTRHAGFPVPDTIYTSPLARGLKTTSLIFKEIIVGQGIEFRPIVKEYLRERLTNHTCDKRRTRQWIQASYPDYELESGFAEEDVLWHADQSESNEAHIARTQELLEDVWRHDSGSCIALTTHSFTISTILEVIGAPEFRMGEGAMVALLVKGEKFNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHR5</accession>
    <name>X0BHR5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14236</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979333">
        <property type="protein sequence ID" value="EXK81376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHR5"/>
    <dbReference type="eggNOG" id="ENOG502RP3U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038610_0_0_1"/>
    <dbReference type="OrthoDB" id="3522308at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF20">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK81376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="380" mass="42694" checksum="21C85A7F053AC73D" modified="2014-05-14" version="1">MSPSCRSIKPRFTSLSPSPKFSEGLRKADRACEKCTRTKKKCDKSLPSCSRCKRLRNKCCYDYVYTPSVTTVIRPENAIKSPPHIPGMLKPFLDISSSMILSLLSSRNAIPSYSIQHYLETINPYLTVVHPELFALRTNSTGSDSICDQELQDPATTLLVVCMQLFSHNDDSGIKGEENVDMPIYRAAKQILSILRALDSPSIELIQCSILLAFYEYTHEDLGRAYVSIGDANTMALILHVAPGKYLEDEREALIPYEEEERRCVYWSLFVLDRLVHTDYSLLHMPYQIPPAVVSPPAADDLLPTNHLLWYDEGQSPYYVTQRYPADTAFSVPVGAFQRNCQYAMLYTGTPSPQSHSGPSAYEWAKPTVTSVLPISSLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHW2</accession>
    <name>X0BHW2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658518">
        <property type="protein sequence ID" value="EXK78453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHW2"/>
    <dbReference type="HOGENOM" id="CLU_174953_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="77" mass="8874" checksum="1BA49B050623473A" modified="2014-05-14" version="1">MQRRELLESALNVPMICVQTFHVDDKQLEKILGDSQQASLLVESRIIIHNTTLANNETQSPLQSIMKDRIKYILDHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BII0</accession>
    <name>X0BII0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_17060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658532">
        <property type="protein sequence ID" value="EXK78254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BII0"/>
    <dbReference type="eggNOG" id="ENOG502SQ1G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115019_3_1_1"/>
    <dbReference type="OrthoDB" id="3183782at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935744" description="EthD domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="EthD" evidence="3">
        <location>
            <begin position="41"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="180" mass="19979" checksum="EE9D40D63C8059EB" modified="2014-05-14" version="1">MNQLASIFLLVSAISGNAAASPKGPTSNTGLLQMVTYVKRNPNMTLNEFWQYWDTQHAPKVIPLATHFGIARYQQVRVAGKIVPTNAGATEPVSNNLVDFDGIAMFLYESADVLINMLSHPYYVNVVEPDEHVFIDKSAHGNGMVATYIGEHIDAVDDAKSVWKGDKKTLSKYQKLFKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJ00</accession>
    <name>X0BJ00_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658519">
        <property type="protein sequence ID" value="EXK78444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJ00"/>
    <dbReference type="HOGENOM" id="CLU_033551_1_0_1"/>
    <dbReference type="OrthoDB" id="5552418at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="285" mass="30586" checksum="D0813950EA962979" modified="2014-05-14" version="1">MDGLGRLRRQNEPPVHSNPKLVQSLNDPSQQLHSLAGISNETYPPAFLAATSSIGRGMGAAGSDISFYSESSASFYTANMPRIATAYGSECGHDSRQAETSDRYSTAARKMYHVGQLSTPSTVYDTQNYSSRQAVVMQKMPPDVASGYFGSETGTSVDPSLQQSARGPNGPASIHQQSNAISYASNSIQRMSTLPQTENAANVSMTDDHNYAEGALEEKWVRYQRQLGSMFQDIVNGSLESASETLLSVTSWLLSQVADLGLNIDDANLSTLIVSSYGTTSITLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJ35</accession>
    <name>X0BJ35_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Epidermal growth factor receptor-like transmembrane-juxtamembrane segment domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_13730</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJ35"/>
    <dbReference type="HOGENOM" id="CLU_041702_1_0_1"/>
    <dbReference type="OrthoDB" id="5347452at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049328">
        <property type="entry name" value="TM_ErbB1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF33">
        <property type="entry name" value="MEMBRANE PROTEIN WSC4, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09020)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21314">
        <property type="entry name" value="TM_ErbB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936344" description="Epidermal growth factor receptor-like transmembrane-juxtamembrane segment domain-containing protein" evidence="10">
        <location>
            <begin position="23"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Epidermal growth factor receptor-like transmembrane-juxtamembrane segment" evidence="11">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="333"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK81861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="389" mass="41092" checksum="80E293028A415EF4" modified="2014-05-14" version="1">MYWPALSSSVFLIGTALQAIHASNVAYGAETRHLPDAPARITEAPLGVIDPMNLLLGNGPGLKPRAESEDSALAVTIAPDETCGYVDADKDSPVTCPSSRLCSWAVSSGVGLVACESQIHITCLESSKAVNSTRCDETCQSNEFNLLCTNSDRPFCLTYVYPSGIFDYRCASTTVEELEHVYFTFEGQKSQNLSTLTLTDEASEGLGEPVTVTVQGKATGSPSAVTIYMIPQPPSDSTASSASPSSSSKSTPVGAIVGGVVGGVAVLGLIGLGIFCLFRRRKKNNRQEYMAGQPNMAHPINQNQHPYHPQHWAVPPYTGTSMVPPAPLDARMSMMTGSASPSGQNAHEGEGQLSPSMVQSPAPAYEMAGSEAREPEPVYEMGGDSPGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJ98</accession>
    <name>X0BJ98_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658490">
        <property type="protein sequence ID" value="EXK78953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJ98"/>
    <dbReference type="HOGENOM" id="CLU_1768166_0_0_1"/>
    <dbReference type="OrthoDB" id="5418036at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="147" mass="17084" checksum="39572925573BC253" modified="2014-05-14" version="1">MPYKQPTSNIFNLELAQRRKNLICTDLTTGPPLQLERTKRPKRAGFSSELGGHDDKYYCTLESEIPFTFAYRLMRAYAIEVERCFTLGHTCRLEVRDNESIRWWRYGRKEDVLAPPDQFEPPEGGDEPSGPPIKLFPVETIEFEVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJP2</accession>
    <name>X0BJP2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16263</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979351">
        <property type="protein sequence ID" value="EXK79098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJP2"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_3_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="74"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="331" mass="36985" checksum="B7D5661AB1084F4E" modified="2014-05-14" version="1">MHPLHPEWTAFVTQNPNIIHDDDQRNGDFLSSVDGHKLATQVLTTDTTIPCRDDHQIPVRIYTAKETQPARGVVIFFHSGAFRHGSLETEDVSCRYMALGGPITVISVEYRLCPAYPYPIPINDGWDAFQYIVTALPNLVPRHTEPVNLVISGTSSGGQLAAIVSQRARDWFKVVENAAIPAKITLSGVLLRAPVTVRGTNAAFIPPRFRDMHHSWSVDFETPGLDRPDMEQSHDVLGVPPEDRSCPDAYPLWGDFNGLPRTYIQICDVDILRDDAVCYSRGLQEVGVDVHESLYKDLPHIFWIYGHHLDVSKKAQEDCVQGLKWLLGLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJS4</accession>
    <name>X0BJS4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycolate phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJS4"/>
    <dbReference type="eggNOG" id="ENOG502SJGU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_19_1_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050155">
        <property type="entry name" value="HAD-like_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43434">
        <property type="entry name" value="PHOSPHOGLYCOLATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43434:SF1">
        <property type="entry name" value="PHOSPHOGLYCOLATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="229" mass="24900" checksum="FD7DF9D7A0578044" modified="2014-05-14" version="1">MPAQLVIFDFDGTLFDTHQAISHSIKLTFDTLLPASAPAESEVQKLIGSGLGLKEVLKELHPSPDSFDEGEWTPTYRRFYNDQGQELVSAFPGAKELLKKLHERQIYVAIVSNKGVAAVETALKNNGIDTIPQDLIVGDNTPGATRKPDTGSFENVLLPALKARGLSHVDGLKTLVVGDTEADVKFAANIGAKSVWCRYGYGEKSACERLKPNFTVDSLDEVAGIVERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJY3</accession>
    <name>X0BJY3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_16211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658479">
        <property type="protein sequence ID" value="EXK79163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJY3"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_27_4_1"/>
    <dbReference type="OrthoDB" id="440755at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF41">
        <property type="entry name" value="MFS TRANSPORTER OF UNKOWN SPECIFICITY (AFU_ORTHOLOGUE AFUA_5G09940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="49"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="509" mass="54667" checksum="00A3E40D34BED4E0" modified="2014-05-14" version="1">MKSMNQPAGVSSVINQIEAVGDSQQLPELLRVASTIKLSKTKQYLITFLILICNLTQFISMFSTVAGGYELSKILGKPVGPGQANWMAAAYSLTQSAFVLISGRLGAVYGHQKLLLLGGVIIVSFSIANAFCNTYNSFIAIRALTGVGGGILMPNAVATLTIMVPPGKVRNFTLAIFAASPPVGAGIGSLMIGAFLEYSEWKWHFISVASLGAICFSGLFFVLPPEQPADRSGKIDCIGIITGLGGLVLFSLAWNQAPVDGWETPYVIAMLITSVVLMVIFFFWESKWADEPIMPPSIFRGKSFKALTVVVLFIYMAVGITLWYMVAWQQLIRGWSVLNVAVGWIPYGLGASCAVILAAWLIPRLEAQWILAIGCLTSLTATILLATMPEQQSYWAQVFPSTVFGSFCPDFVYVAAQVIASSSVGKKEQGPAASLIGTLNLYGNSLGLGFAGTIETNIAKSHAGEALGFRSALWFGAGLSAIALLMDLTMVRMEKEDKEGWDSNETELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK20</accession>
    <name>X0BK20_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histidine-specific methyltransferase SAM-dependent domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658476">
        <property type="protein sequence ID" value="EXK79213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK20"/>
    <dbReference type="HOGENOM" id="CLU_2121222_0_0_1"/>
    <dbReference type="OrthoDB" id="5091886at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="1">
        <location>
            <begin position="4"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="114" mass="13385" checksum="EEF29FA4C6F482D5" modified="2014-05-14" version="1">MPGKKVGISYSSTLTDFEPKKLHRILQGWHEVVDQLIVGQHEPVEKKELEISYHTTQFTEFVRGGWDQANRLLGWTEFDDERWKLHGGLSAHNPELRMESIEMLPRWEDQDVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKF2</accession>
    <name>X0BKF2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Salicylate hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_16016</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658473">
        <property type="protein sequence ID" value="EXK79363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKF2"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_3_1"/>
    <dbReference type="OrthoDB" id="5428495at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000115">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF306">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="44"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK79363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="463" mass="51287" checksum="12942806C4CA876F" modified="2014-05-14" version="1">MAKNKITQPAAAYPSRSTSLLERLHHTAEHANGNGHFSGSQVKLQVLVVGAGLGGLATAVALARQGHEVTVLEQAAVLGEVGAGIQIPSNSCRLLLKWGLGPYLEQYAVKPDSMTFRRWENGDPIAYTRLSPDFETRYGAPYFVIHRADFHRALCRRAEDLGVKIVTDSRVTDYDESIPSATTFDGREYRADLVIAADGVKSQARSVVLGGLDLPPQKTGFAAYRATVNTEEMERDEDTAWLLEKPGINIWIGEDRHVMTYSIAGGNSFNMVLSHVDHSSPSTWNAENAIRDMQDSFKDWDPKLFKVIKMIKSTLKWPLMSGSRLQTWISRSQKLLILGDAAHAMVPYMSQGAAMAVEDGAALATAISKIKCKDQLKTALHIFEKERMNRSYGMQSASLVNGKLWHFPDGPLQQARDLGMRAEVEGRQFVESTNQWSDPVTQIWAYGYDAEDAIDELWQSEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKL8</accession>
    <name>X0BKL8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase M24 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKL8"/>
    <dbReference type="eggNOG" id="ENOG502SGBE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052604_0_0_1"/>
    <dbReference type="OrthoDB" id="9995434at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01066">
        <property type="entry name" value="APP_MetAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050020">
        <property type="entry name" value="DddP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050659">
        <property type="entry name" value="Peptidase_M24B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF043017">
        <property type="entry name" value="DimsulpropLyDddP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46112">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46112:SF8">
        <property type="entry name" value="CYTOPLASMIC PEPTIDASE PEPQ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="2">
        <location>
            <begin position="230"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="456" mass="51088" checksum="0774355FBC2F6282" modified="2014-05-14" version="1">MKKKEESVKLSSPCALPAISRRIDPTKPRTSKLKPDGSNHNNDRVDIGPTPLAFTEWEQLGLQSPHLPTMRAYRLQRICDQLIARDLGGILLFDPLNIRYATDTTNMQLWTAHNPARACFIVASGYLVLWDFHGCEHLSSHLPLINEVRCGASFFYFETGNRTDEHAVHFGAQVDELLRKHAGDNRRLAVDRIEVAGLRALEAQGIHICDGQAVTEHARMIKGPDEILAMRCAIASCEAALGEMRQAMRAGATENDVWAALHAGNIRRGGEWIETRLLSSGPRTNPWYQECGPRVLRDGDLVALDTDLIGVYGMCVDVSRTWICGDVEPTVEQKHLYRIAHEHITTNAKMVKPGVKFTELTRNGHRLPESCRAQRYSVMFHGVGLCDEYPCIRYPEDLDSYGYEGELQAGMVLCVEAYVGEVGGKDGVKLENQLLVTDTGYELLTHYPFEESFLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKY0</accession>
    <name>X0BKY0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_13222</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin oxidoreductase frp family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKY0"/>
    <dbReference type="HOGENOM" id="CLU_615451_0_0_1"/>
    <dbReference type="OrthoDB" id="2094932at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="entry name" value="NADH Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016446">
        <property type="entry name" value="Flavin_OxRdtase_Frp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43425">
        <property type="entry name" value="OXYGEN-INSENSITIVE NADPH NITROREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43425:SF2">
        <property type="entry name" value="OXYGEN-INSENSITIVE NADPH NITROREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="FMN-dependent nitroreductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="5">
        <location>
            <begin position="206"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK82511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="445" mass="48993" checksum="2B0F42888D752D1A" modified="2014-05-14" version="1">MLSAANLKAAQQVVYSRALAQRGRSRDASSGIKAPLSVRAAVKNNAGSNKSSVARIIKLLEAANVPDAAAVAFPTMGRPRMLTDEENEAIMAFVIWREGAGLPACKGVKLKMQQIHYASAGTQKRSQSAECGTAASVTIILKWFERLTEAIVNRRINASECWNADQTVVRVGILREHVQCLIMHTKREVRVQVLSPEYRETCTVIVRKFLPDEKLPEGALETLTAASQSASTGSMLQSWSAIAVIDPERKSHVATLAGDQEFIREAPLFILFCADLSRLHDASDYHGRPGDGAGLECIDLFIMATLDAALAAQNVTVAAESLGLGMCYVGAARNNARDLPDYLGLPPYVVGLLVMAVSYAEPKYLNSHKPRLSISEVMYRDIWKDEERAEHIKKYKDTLQNHYKRQNKPGRKVWRVSLANCMSSSDLDGRGKMRSVLDQQGFKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKY7</accession>
    <name>X0BKY7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_13088</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502T2F6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_15_1"/>
    <dbReference type="OrthoDB" id="1577640at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="4">
        <location>
            <begin position="2"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="5">
        <location>
            <begin position="185"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="672"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="738"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1014"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1313"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1346"/>
            <end position="1378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK82516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1504" mass="168109" checksum="7E0100E9B3ECBE9F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLY2</accession>
    <name>X0BLY2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658454">
        <property type="protein sequence ID" value="EXK79913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLY2"/>
    <dbReference type="HOGENOM" id="CLU_2687897_0_0_1"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF3">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G11600)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="74" mass="7943" checksum="BFE1399B43C46EBC" modified="2014-05-14" version="1">MANSGTLIFATVGAKSSIEKMRPYIKGVMGHDEISFEDEPYSNAAKLKLMGNAFALNAITQLAESLTLAEKIGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMN3</accession>
    <name>X0BMN3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_12632</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMN3"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000489">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000012">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF199">
        <property type="entry name" value="MFS EFFLUX TRANSPORTER INPD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="249"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="549"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="624"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="159"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK83111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="656" mass="70933" checksum="1F59F36D2C0CD328" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNS5</accession>
    <name>X0BNS5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Endo-xylogalacturonan hydrolase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_15333</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Pectinolytic enzyme involved in the degradation of xylogalacturonan (xga), a galacturonan backbone heavily substituted with xylose, and which is one important component of the hairy regions of pectin. Activity requires a galacturonic acid backbone substituted with xylose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658452">
        <property type="protein sequence ID" value="EXK80114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNS5"/>
    <dbReference type="HOGENOM" id="CLU_016031_1_3_1"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF9">
        <property type="entry name" value="ENDO-XYLOGALACTURONAN HYDROLASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937064" description="Endo-xylogalacturonan hydrolase A" evidence="15">
        <location>
            <begin position="21"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK80114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="41899" checksum="7FACC124D0AC4178" modified="2014-05-14" version="1">MFKIFLKTVAAANLIGLAAADPIPIVPDRVRLGPRASACTPQAGRSSSVDDVPAIQAAIKACPSGTIVIPSDQTYHINSQLSFAGCSGCTFELNGELLASTDFGYWNGRGEIIYLQNIRGATITGSGTINGNGQASWDYIITNTSYKRPYLIRVDGSTNIKMSEITIKNAPSFHVVTSGNSKDVVYSGLTLYSVSSSSNIAHNTDGFDIGPASYVTVENTKITNDDDCVVLKPGASYVTTTGVTCVGSHGLSIGSLSGGAGSNDIVTNSIFKDCTMIGSTKAAGIKYYPGGSTHGTGSISNVTWQDITCDTCDYAIQISTCYMSTPAACSANPSTGKISGVVFSGFSGTTSGHYKDVVANMDCSVGGTCGIKIEDFTVTAPSGESEVLCAHTPNNLGVVCTSGASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPK1</accession>
    <name>X0BPK1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658446">
        <property type="protein sequence ID" value="EXK80404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPK1"/>
    <dbReference type="eggNOG" id="ENOG502RXCZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_0_2_1"/>
    <dbReference type="OrthoDB" id="190201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046503">
        <property type="term" value="P:glycerolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="28"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="306" mass="33423" checksum="1BDD10F1983CF4DE" modified="2014-05-14" version="1">MNTSPELFAQLTNRLRICYQTFGDPSDPAVILVPGNADSMIVWAEDLIEKLQSSEDGKKYFVIRFDPRDTGLSTEFPVPGGYSIGDMAGDIEGLANHLNLNDPSKGFHIVGLSKGGPVAYTVAARMPQHVKSLSLLYTSPGVSPELPIKGGLDLGFQPMLAGFGDQRETAIKNGMTVYDALTTQPDAEERKEVEKAVRRLVERDIKGGTLYSKAPNHGAASYEKDGWPGVDTLKMIKCPTTVVQAGKDQIFGEIHGEALAKAIPGNVEYVLWDDVGHEMPRRIWSRMAKVLQKNWERGQSADHVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPS4</accession>
    <name>X0BPS4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_15021</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658443">
        <property type="protein sequence ID" value="EXK80479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPS4"/>
    <dbReference type="HOGENOM" id="CLU_006072_1_3_1"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF397">
        <property type="entry name" value="CALPAIN CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="5">
        <location>
            <begin position="49"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="501"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="759"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="522"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="613"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="698"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK80479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="813" mass="92456" checksum="0B29276DFAF5342B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPU6</accession>
    <name>X0BPU6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">4-hydroxy-2-oxoglutarate aldolase, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11843</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPU6"/>
    <dbReference type="eggNOG" id="ENOG502SG3E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_0_2_1"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF47">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="2">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK83891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="36635" checksum="A14EFC023DD94475" modified="2014-05-14" version="1">MGSLNPAPSQQPHVPSPGVWCPAVTFFNHSDDTVDHASQAKYFAHLADSGLNGLIVMGSNAEAFLLTREERYELIALARKTIGPDFPLMAGVGAHSTKQTLELAEDAHKAGANYLLVLPPAYFGKATSMNVVKRFFSEVAKKSPLPVVIYNFPGVTNGVDIDSETIVQIYEESKKSHPSGKSNVVGVKLTCGSVGKITRLAAQIPSSEFSTYGGQSDFLIGGLAAGSVGCVAAFANVFPTLTSKIYALYKESKFEEALKLQQLAALAERPCKAGVASTKYAVAVFSARLAGVEGAEEKLAPRHPYEPVGEAVKASVKSIMKEAGDKEEELLKTWTDRVKGRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQU1</accession>
    <name>X0BQU1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658435">
        <property type="protein sequence ID" value="EXK80849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQU1"/>
    <dbReference type="HOGENOM" id="CLU_1407463_0_0_1"/>
    <dbReference type="OrthoDB" id="5002400at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRAM" evidence="1">
        <location>
            <begin position="52"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="200" mass="22259" checksum="D9413683EA74072D" modified="2014-05-14" version="1">MDLRSDDVLPGEKVLMKKAANAMININDYKLSRFFADDLARLFGKENLEAIGGKLYLTNYRLLFKSHSINRVTGKFSVALPTIIAVEDTSKFLTKRIDVTTSTETFQFVVWGIPELIDKINETRLALEPVEVKRLQSLVLENYKVFGDGMTVAKSIEGINKAFLAARKAGVLTELATRAGNPLEITGILNFLELMGDEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRK7</accession>
    <name>X0BRK7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_11055</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRK7"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_4_1"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015667">
        <property type="term" value="F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140115">
        <property type="term" value="P:export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017985">
        <property type="entry name" value="MeTrfase_CN4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF164">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00093">
        <property type="entry name" value="N4_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="62"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK84810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="533" mass="58300" checksum="2D148892FC4AB2F1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRN8</accession>
    <name>X0BRN8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658429">
        <property type="protein sequence ID" value="EXK81144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRN8"/>
    <dbReference type="HOGENOM" id="CLU_004471_2_3_1"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="673"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="927"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="927"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1007"/>
            <end position="1033"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1033" mass="117351" checksum="A219FA612ECE3DEA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSL0</accession>
    <name>X0BSL0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aromatic-L-amino-acid decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14111</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSL0"/>
    <dbReference type="HOGENOM" id="CLU_011856_3_1_1"/>
    <dbReference type="OrthoDB" id="639767at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1340.10">
        <property type="entry name" value="dopa decarboxylase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF70">
        <property type="entry name" value="MIP05841P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK81474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="492" mass="54645" checksum="B2CB68738A2B4382" modified="2014-05-14" version="1">MDSAQFREAARTAIDEITDYYDNVSSQRVVSDVKPGYLRPLLPSSAPLEGESWTDIHADIESKILPGITHWANPRFMAFFPCSSSYPAALAEMYSNTFNGAHFNWICSPAVTELETIVMDWLAKALGLPECYLSGGSTHGGGVIHGSASEAILTVMCAARDKYLAAVTRDMDEDAVWDVRSKLVALGSAGSHSSTKKAAQVLGVRFVAIPVTEEDGFAMTGRAVAKTVAELRARGLEPFYLTATMGTTDVCAVDDFAGIVEALSPTAGTEKDIWVHVDAAYAGSALLLEENQPLTTPMADFHSFNFNPHKWMLTTFDCSAVWVRSRAWLIESLSIKPPYLRNQFSDNELVTDYRDWQIPLGRRFRSLKLWFVLRSYGVRGLQAHIRNGVTLGESLQTKLASRPDLFTIFTSARFGLVTFRVKGADETEINARTEELYEWVNRTGEFYLTSTIVNDKFAIRVCTGVERVREEHVQRIFDVLVERTEADLGKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSQ9</accession>
    <name>X0BSQ9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658426">
        <property type="protein sequence ID" value="EXK81529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSQ9"/>
    <dbReference type="HOGENOM" id="CLU_1570720_0_0_1"/>
    <dbReference type="OrthoDB" id="5106179at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="170" mass="19906" checksum="8D2486588585E891" modified="2014-05-14" version="1">MSGCHGSDPTRTTQKIPFPIWLIDHRNLQAHLQSLKNLKMLAIQGDAYPPRMNEMFGYNSYYRQDMANAEDFQTARDHPELAPFVQGRGDSKLYWEHAHLYRMLEYARSYRKVLPKLEWILCGRRPMKFVENDQGVVQPHPIGRRQDECKTFIGRVFGLATKIETAHEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSW8</accession>
    <name>X0BSW8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">urease</fullName>
            <ecNumber evidence="2">3.5.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_13669</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Ni cation</name>
            <dbReference type="ChEBI" id="CHEBI:25516"/>
        </cofactor>
        <text evidence="7">Binds 2 nickel ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Carbamylation allows a single lysine to coordinate two nickel ions.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.5" evidence="2"/>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK82028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSW8"/>
    <dbReference type="MEROPS" id="M38.982"/>
    <dbReference type="eggNOG" id="ENOG502QPKB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000980_0_1_1"/>
    <dbReference type="OrthoDB" id="1708534at2759"/>
    <dbReference type="UniPathway" id="UPA00258">
        <property type="reaction ID" value="UER00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035550">
        <property type="term" value="C:urease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00407">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00390">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.150.10">
        <property type="entry name" value="Urease, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.280.10">
        <property type="entry name" value="Urease, gamma-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01953">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011612">
        <property type="entry name" value="Urease_alpha_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050112">
        <property type="entry name" value="Urease_alpha_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005848">
        <property type="entry name" value="Urease_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017951">
        <property type="entry name" value="Urease_asu_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002019">
        <property type="entry name" value="Urease_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036461">
        <property type="entry name" value="Urease_betasu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002026">
        <property type="entry name" value="Urease_gamma/gamma-beta_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036463">
        <property type="entry name" value="Urease_gamma_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029754">
        <property type="entry name" value="Urease_Ni-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009686">
        <property type="entry name" value="PRK13207.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01792">
        <property type="entry name" value="urease_alph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00192">
        <property type="entry name" value="urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43440">
        <property type="entry name" value="UREASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43440:SF1">
        <property type="entry name" value="UREASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00449">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00699">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00547">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01752">
        <property type="entry name" value="UREASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51278">
        <property type="entry name" value="Urease, beta-subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54111">
        <property type="entry name" value="Urease, gamma-subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01120">
        <property type="entry name" value="UREASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51368">
        <property type="entry name" value="UREASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0533">Nickel</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urease" evidence="10">
        <location>
            <begin position="400"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="591"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="7">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="7">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="543"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="631"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="6">
        <location>
            <position position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK82028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="764" mass="81986" checksum="40EAFDF089699EFF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSX9</accession>
    <name>X0BSX9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Fructose-1,6-bisphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_14012</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; Calvin cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FBPase class 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658425">
        <property type="protein sequence ID" value="EXK81599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSX9"/>
    <dbReference type="eggNOG" id="KOG1458">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039977_3_0_1"/>
    <dbReference type="OrthoDB" id="3886144at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023079">
        <property type="entry name" value="SBPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF35">
        <property type="entry name" value="SEDOHEPTULOSE-1,7-BISPHOSPHATASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01958">
        <property type="entry name" value="S17BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="9">
        <location>
            <begin position="54"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="10">
        <location>
            <begin position="207"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK81599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="332" mass="35440" checksum="ACA10B5F323D5EB0" modified="2014-05-14" version="1">MSSTKAPELELAPFLKSALPQENRASLRDSVIPQLLSAIADIGKGLRGSYDVSIVGTENAFGDEQLNVDVLAENIIRDSIAKSSAIKTASSEEDPVEKPARAGETTQADSSAEQYTVAFDPLDGSSIIGPNWSVGTIVGIWDGVTAVGQSTEKQIASVLGVFGPRTLAIVALRAPGSKPVCFEVSLNDTQKFVVARPELRLAEPPFKTRYFAPANLRAAAENEKYMNLVTKFITDKYTLRYSGGLIPDIYHALVKGHGVYISPVTSASKAKLRRLYELLPVALVVECAGGQAIDPETGARVFDTILKGCDDRAGLVCGTSEEVEKVKKALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTC6</accession>
    <name>X0BTC6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTC6"/>
    <dbReference type="HOGENOM" id="CLU_044233_0_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF2">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="499" mass="56331" checksum="3B33A3310FCB2CB6" modified="2014-05-14" version="1">MIGSMRRQSTSVAQLFPKRVSRHAKLISLNRYHFEYKPSVSPLSSHQLHQHNERCSGSVPCSNCVRRRVECTFEQQKPKQIWINQDESGKKVVTRVSAVTCKSQSPRLDLNPTGDQIYYLSHYFETFLRRNSCNTKTDIFTDVIGLMKDQASGTFLHDAVLSLGAMQAVKLNASEGIDPSKTYNLAVHYYSKSVLGLRNALEKFDQEPSARHRILWTTHLLGLFELMTDATGEGWIQHLVHGTSKALVAAGPTSCQSGHGLRFFTEIRIFEVCRAIIFNEPTFLAKADWRCLIREMRAKEQGNADLLDELLDIIVSCSTLRVRAKDLIYYSDADDVNLPKHLDEAFDVAQEGFRLRQALIDWEAKGVPSKQLTAENTSGSFSSLTKAFFAATSIYLSGVFDYEIPYWQDMGIVAPNLSEEEIQMHVINILTHTNSVLYNSSISPLLVLFPLRVAGARSWQGWQQDCIMQNLLVVERTFPVAAAFRADLMGVWARMSPPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUL7</accession>
    <name>X0BUL7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979330">
        <property type="protein sequence ID" value="EXK82164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUL7"/>
    <dbReference type="eggNOG" id="ENOG502SI2J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_1_1_1"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19075">
        <property type="entry name" value="AKR_AKR7A1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="325" mass="35492" checksum="3E7C1E77B11D5542" modified="2014-05-14" version="1">MTSAGKSPLKLILGAANVGDKEADPWARYDTPDEVNAFINVFARRGYTQLDTAAVYSPQAPYSSEPRLGAVNAGERFGIDTKADFMKGHTKENITHDIDNSLKLLKINQINVYYLHIPDRNNPVEPAIEALDQGYRDGKIKAWGISNFRANEVQQVIDICEKRGFVKPAVYQGHYNALVRAGEKELFPILRKNGMAFYAYSPAAGGLFSGSHKSPAPNGRFDTAHKSGSITHSLYIKPSILGAVDKAIEVFAKHDIGGHAAALRWTAHHSILDKKYGDGLIIGASSPQQLESNVDTIEEGPLPEEVAAALNAVYEEVGDEVSYHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVC4</accession>
    <name>X0BVC4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">D-malate dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="4">1.1.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_13172</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(R)-malate + NAD(+) = pyruvate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:18365"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15588"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.83"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.83" evidence="4"/>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVC4"/>
    <dbReference type="eggNOG" id="KOG0785">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_1"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046553">
        <property type="term" value="F:D-malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050501">
        <property type="entry name" value="ICDH/IPMDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011829">
        <property type="entry name" value="TTC_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02089">
        <property type="entry name" value="TTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43275">
        <property type="entry name" value="D-MALATE DEHYDROGENASE [DECARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43275:SF1">
        <property type="entry name" value="D-MALATE DEHYDROGENASE [DECARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="11">
        <location>
            <begin position="6"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK82459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="361" mass="39536" checksum="7AA21C125BC9B168" modified="2014-05-14" version="1">MSKTLKIAVIPGDGIGKEVMPYGVRCLKAAAKKFNISLEFQEFDFASCDYYEKHGKMMPDDWKDTLQNFDAIYFGAVGMPDQVPDNVSLWGSLLKFRREFDQYINLRPCRLMPGIPSPLAGRKPSDIDFWIVRENTEGEYSSVGGIMFEGTERETVIQDTVMTRVGVDRVLRYAFDLAQSRPRKKLTSATKSNGISITMPWWDSRVAEMSKNYSDVAVEKYHIDILTAHFVQRPQIFDVVVGSNLFGDILSDLGPACTGTIGIAPSANINPTGDFPSLFEPVHGSAPDIYGKGIANPIGMIWAGQMMLSHFGYADAAAGMMTAIETVLASSGAEVKTADIGGNGNTQTLGEAIEKEILSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVL9</accession>
    <name>X0BVL9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVL9"/>
    <dbReference type="eggNOG" id="ENOG502S3SW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_637845_0_0_1"/>
    <dbReference type="OrthoDB" id="94039at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="430" mass="48355" checksum="8EE76A1A471874C4" modified="2014-05-14" version="1">MSFDLSTTYERALLRPLVLPPIDPTATNESAGLSEGSKWRASTHIFRGTEDRDETDAWPPAKFNDDPSNIPNDEAYNIPYDTASKKANSSIFKLYSDSGQSNKSNVPPPRLVAKRYIPTNQVNKSGQGVTLLTLTGMGVPKEMFEPMLEDLLPRLRKSGVKVEEVWAIDMPLSGQTAKANSVGYLYANEKDIVRDLLLFLTAYLPVQPGEELPKHLQPRTTTDQAQQPTRQNLHVFSHSLGAQAAILASVHAPNIFSSLMVVDPAMIPAGKINDAMTKLPKEIFCLGLKENFPDRNAVENALRENKRTRNWDERAIRMFTQHGLVPNDKGGVKLIAHPRLDWALWYDKQTPAECYDRFRDISVPLLAIMPKRPFAVPAKMFEADVKKLKERIYVRWVEGTHQVVYERMDDCVGFVGEWLGDIAGEKRAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXJ3</accession>
    <name>X0BXJ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXJ3"/>
    <dbReference type="HOGENOM" id="CLU_1906831_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="154" mass="17222" checksum="1C532B13D1014EAE" modified="2014-05-14" version="1">MSMCSNTARCQHRPSSTANITNAHLLEGLCIHHKKQTAFNIMTLSFILVFPSPDFLRDLRSALAAIPYSDPITPHKYVCILNKSHDVGWTCMPFQLLGYELEGLSPQRPAPAFSVCTYVYTLAHLLDVPMDGSVTRNICSVFDRENEFPTNTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BY44</accession>
    <name>X0BY44_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BY44"/>
    <dbReference type="eggNOG" id="ENOG502RIWD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_891506_0_0_1"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK86781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="316" mass="35007" checksum="222C088D677E3644" modified="2014-05-14" version="1">MGIKPQFFLVRPGAEQITPTGQVLSQPATAVPLIPADLLPEWIEVIGAPRSLSPDETRDMGNLGVIHAELDTYKLRFAPITRDGASTSDKSDTSEERATGFRPGPYAEGASSSHNYYEKPKPTTTTTQLNTPKSKLKPAQGLSSSRHNPANQQQPAHLSPTSHKETPQIPTNTTAPSSQLPSLCRHWCHHGVCKWGRDCHYEHIMPVTAEGLGEVGLTGFPDWWLQARGLMPMPPQALRAADAPNGRRTARKIGNLLRRKQRARILAQRRDVHFRNLEEGSEAEDEYEDEEDVEEEVVKPEPKRGGEEEGILIDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYG7</accession>
    <name>X0BYG7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYG7"/>
    <dbReference type="HOGENOM" id="CLU_880121_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="316" mass="34890" checksum="DC6B9359932A7183" modified="2014-05-14" version="1">MAYLMILNPMRAFMAQVYTRNSPADLLAVRKDAVFYSLKNLDTTTRWADHASHRDARFHFIIFSLFDTAAVLSTAVIKDQDDTIPRKDEIVDSVDNAIRLLKRLKALSKTAKTSHDILVKMVQKMPRRSAPPRETVNRKKQRVAPVSPAAPATNTRHDVVIKPEDGYHPEHVSQESSPSYYASSEGAPSGSTPQSTHSSYDNHENTGYAMNNQVPAEGYAKPQVAYNMGVAPGHMPPQQVPSPSAGIDGIVQGGLYGMPHADHTGGGMVPPTYVDYHPQDLNIDYGLGNITDVDLGDFSQLWDWRSLNLDFIQSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYG9</accession>
    <name>X0BYG9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19647</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658798">
        <property type="protein sequence ID" value="EXK75587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYG9"/>
    <dbReference type="HOGENOM" id="CLU_2812471_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="67" mass="7254" checksum="C8162EF34A8C8E8F" modified="2014-05-14" version="1">MNDLSQSVAIACIASISRSRLQGTTQTSIDDILQGTDAPTTSAAREALPECGVRRRRYGCTGDHWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ18</accession>
    <name>X0BZ18_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979821">
        <property type="protein sequence ID" value="EXK75777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ18"/>
    <dbReference type="HOGENOM" id="CLU_110793_0_0_1"/>
    <dbReference type="OrthoDB" id="27975at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="231" mass="26149" checksum="48F9A58EDEEC9DDE" modified="2014-05-14" version="1">MAVSSEPFSQHLTMCWHQELALRATRFWNTLSTSEQDMRRHTVLMAACRHQDIFYLVIHQLCCLWSIDKAAVHDIFDSLTALQNVDSTFDTIQQILNNDDLSPCGLRWYASFPQPIREALTGSGGKTFATHLVSFMGHFATLWHPLLDQAGLEDQPISGSVLKHDLDCSSPILRYILFVASSLQIGIVAGPDATILDEKFEKDETDKYSIRGESVREVLASEHTRLLHHHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZL7</accession>
    <name>X0BZL7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_19262</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979673">
        <property type="protein sequence ID" value="EXK75977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZL7"/>
    <dbReference type="HOGENOM" id="CLU_004291_1_0_1"/>
    <dbReference type="OrthoDB" id="2154091at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="283"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="19"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="477"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="622"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="688"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="640"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK75977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="877" mass="96704" checksum="CEACD7CB63B57609" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C063</accession>
    <name>X0C063_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11366</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C063"/>
    <dbReference type="eggNOG" id="ENOG502T44N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2090471_0_0_1"/>
    <dbReference type="OrthoDB" id="5024906at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="131" mass="15348" checksum="06C219F1043DB908" modified="2014-05-14" version="1">MSSITNPRKYTIAFKFLETDTIQGNQIAAGNNLFKPIRQKYGDRLEECEVDEWRLFITISQCLHADGEQLYEELLIVLEATELFHQDGIFAEPQLFEWAVFEETEEGLKQSSNHRSATLGLFHTYKWRIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C214</accession>
    <name>X0C214_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_18432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658677">
        <property type="protein sequence ID" value="EXK76837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C214"/>
    <dbReference type="HOGENOM" id="CLU_011226_14_2_1"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF3">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR URE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="93"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK76837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="28968" checksum="209613EABE0EB0AE" modified="2014-05-14" version="1">MQSIKIYHGPPGTGPNPWKVIIVLKELSLPWEFVWIPYSEIYKEPYLSLNPNGRLPAMIDPNTNVTLFESGAIVQYLIDQYDNKHLLSYPVDNLQEKWATNSWLMVQMSGQGPMFGQKMWFTYFHQKRNVETAISRYGEQSRRIMQVINEHLRKRRQELKLDIDSPVWLVGDRCTYGDLSFVPWNILLLTALFPDEELKPEENYPEWFKWHQEMIARPAVAEALKERAHAMETMEDTAAAVLPQRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0C261</accession>
    <name>X0C261_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_10623</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C261"/>
    <dbReference type="eggNOG" id="ENOG502QYWX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004083_5_0_1"/>
    <dbReference type="OrthoDB" id="2269373at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF45">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="76"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK85243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="690" mass="78451" checksum="3FFD917A65EBF371" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2G4</accession>
    <name>X0C2G4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U3 small nucleolar RNA-associated protein 11</fullName>
            <shortName evidence="6">U3 snoRNA-associated protein 11</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_10926</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Nucleus</location>
            <location evidence="2 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UTP11 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2G4"/>
    <dbReference type="eggNOG" id="KOG3237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061887_0_1_1"/>
    <dbReference type="OrthoDB" id="29058at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015952">
        <property type="entry name" value="U3snoRNP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="137"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="203"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK84964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="268" mass="31173" checksum="4A8AF07EEE6F9A6F" modified="2014-05-14" version="1">MSSMRNAVARRPHRERAQPLERRRLGLLEKHKDYSLRAKDFNKKKAQLKNLKEKAAERNEDEFYFGMMSRKGPGSKIQDGKRWSGTVEGDRGNKAMDVETVRLLKTQDIGYIRTMRQVVAKEVARLEEQVVLTRGFDKLDEDEDDEDEGSDSEFDFATAPSRPKEPRKIVFMDDEEQREETILDLEDEDDADKTFEGFDDDKKKEAEFERAKALRRLRRQLENARKKLKALTDAEGELEIQRAKMAKTATSGGTTRKGKKIMVRTRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2Z2</accession>
    <name>X0C2Z2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_10804</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2Z2"/>
    <dbReference type="HOGENOM" id="CLU_028200_0_2_1"/>
    <dbReference type="OrthoDB" id="3648173at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="28"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK85149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="371" mass="42165" checksum="3E5467001BBB5591" modified="2014-05-14" version="1">MKEGDTRAPLILGVVLTLLLLTFSVVLLRVYTRAMLLKQFGADDIWAVLSMASIASCAFSILLGIKYGFGRHQVFLTEEESRNYFKVFYVSIILYLVSLGAIKTTLLCQYYRAFAINKMRTVLLVAIVFVSAWSISQIFLNIFICTPIAAFWDRAIEGKCIPRNPTWYITAAGNIATDIMIIVLPFPVVIKLNLARRQRFVLLGVFCVGFLTCAISMIRMGYLDIKEDLTWVNVESACWSFTELCCGLLCACVPTLRPFVSRYFPSMSSYNRSRKTYATNQPPEPHTANRYHEIELQNGRHIQEDLLQDDSRSTRILCVSEFTVTETRELVNKKHGERESDDEVLLVSHVFADPRPIEKARTRPGRLPATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3C4</accession>
    <name>X0C3C4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658625">
        <property type="protein sequence ID" value="EXK77267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3C4"/>
    <dbReference type="HOGENOM" id="CLU_058336_1_0_1"/>
    <dbReference type="OrthoDB" id="414463at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00730">
        <property type="entry name" value="Rossman fold protein, TIGR00730 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223:SF70">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="210" mass="22658" checksum="E6501EE8394BB143" modified="2014-05-14" version="1">MSSPTPRTKICVYCGAGTGVSPAYMEAARALARVMAANNMDLVYGGGTVGLMGEIAETLVSINGPQSVHGIIPEALVQYERAGSRERHIPDEAIFGRTTLVKDMHTRKKIMAEEVFAGGPGSGGFGTMEEIFKTTTWIQLRIHSRGIVLLNVEGYWDGIIQWLDKATEQGFVKPGNKGLLAVADSAEGAINALLEYKVSDSIYHLKWGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3V4</accession>
    <name>X0C3V4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF521 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10269</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3V4"/>
    <dbReference type="eggNOG" id="ENOG502RQJN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018825_2_0_1"/>
    <dbReference type="OrthoDB" id="2594507at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01355">
        <property type="entry name" value="AcnX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01356">
        <property type="entry name" value="AcnX_swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.10">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012047">
        <property type="entry name" value="AcnX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007506">
        <property type="entry name" value="PMDh-L-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002840">
        <property type="entry name" value="PMDh-S-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36577">
        <property type="entry name" value="DUF521 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G00490)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36577:SF3">
        <property type="entry name" value="DUF521 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G00490)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04412">
        <property type="entry name" value="AcnX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01989">
        <property type="entry name" value="AcnX_swivel_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036630">
        <property type="entry name" value="UCP036630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphomevalonate dehydratase small subunit-like" evidence="3">
        <location>
            <begin position="30"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphomevalonate dehydratase large subunit-like" evidence="4">
        <location>
            <begin position="171"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="63941" checksum="B1855C4B0C699ACC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C444</accession>
    <name>X0C444_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK85948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C444"/>
    <dbReference type="HOGENOM" id="CLU_2184047_0_0_1"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="109" mass="11948" checksum="345774364888FD88" modified="2014-05-14" version="1">MQFDEYLNKTLGATDADMAKRERWRNDGYMMGAGNPVIPMVPMAMPPSAYHAQRQAAAMNYDRDDDSDSKTDSDEEFNDDVKQARKGKSGAAQKEGSATTGETPGDTYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4S0</accession>
    <name>X0C4S0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Epoxide hydrolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_07515</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4S0"/>
    <dbReference type="eggNOG" id="KOG2565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_0_1"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936761" description="Epoxide hydrolase N-terminal domain-containing protein" evidence="5">
        <location>
            <begin position="20"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="6">
        <location>
            <begin position="34"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK89410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="405" mass="45439" checksum="78E3E57462DC3DD0" modified="2014-05-14" version="1">MRSFLSIAFLTSSLFHVDATPTPRDGKGSSFNLKPFTINLSHGVPHMIDLAKRTNLPTNGDYLAPDAGIPLQTLVSLRNELIDNFNWEAEQRKLNKFHHFTADIENQTIHFIHQKSHNPKAIPLVLNHGWPGSFLEFIPLIEKLKDDFHVIIPSLPGFAFSSAPPPTWTIHDTARVFNTLMTKVLGYPKFAAYGTDWGSGVTYSLYANFNTSVRLAHLSFLPFTPLDRTQLAAEDIKLSPLEEFEAKLSEEWAKTGNAYFMEQLTKPNTIGLALYDNPIGQLSWIGEKLIAWSDPRAGSPPSVLDHNEMLKTVALYHLTKTFASSVYIYYSNPAGFMTTYTKANTDAPMLFSAFKYNVGFWPPELVGRVGNLVSYKNHEFGGHFPGLDNPVALAEDLKDIKKYWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6D8</accession>
    <name>X0C6D8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07746</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6D8"/>
    <dbReference type="eggNOG" id="KOG0734">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004471_6_3_1"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="528"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="777" mass="89712" checksum="408864E7348538D6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7H0</accession>
    <name>X0C7H0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Heavy metal tolerance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_09419</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7H0"/>
    <dbReference type="eggNOG" id="KOG0056">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18583">
        <property type="entry name" value="ABC_6TM_HMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000287">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF503">
        <property type="entry name" value="MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="504"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="285"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="602"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="197"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="854"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="873"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK87148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="976" mass="108295" checksum="A3E78C0CEAF7DC1A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7P4</accession>
    <name>X0C7P4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7P4"/>
    <dbReference type="eggNOG" id="ENOG502SZDW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158824_0_0_1"/>
    <dbReference type="OrthoDB" id="4338954at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="103" mass="11941" checksum="A8C7BE16756FFE9B" modified="2014-05-14" version="1">MMRVPRQSFSTAARIHPNIVPHLRPQKRMSFGKLVKPVAAVVAIGYGAKLSLEMAQRRRIAQMEAMERENAAYRERNEALMNMYGDRSSLDELEKAVQYYEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7X7</accession>
    <name>X0C7X7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial import receptor subunit tom-22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_07067</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom22 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7X7"/>
    <dbReference type="eggNOG" id="KOG4111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094333_1_0_1"/>
    <dbReference type="OrthoDB" id="10016939at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22884">
        <property type="entry name" value="TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005683">
        <property type="entry name" value="Tom22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04281">
        <property type="entry name" value="Tom22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="124"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK90211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="16856" checksum="E3A59D280AAAE59D" modified="2014-05-14" version="1">MVTLTEVEDEHFQHPQAGPDIEEDDDDYSDTDSEISNESDYDPSEETLAERLYALRDIVPPTTRSWISGKANTIGNAAWSVLSFSGKGAWVLTTSALFFGVPFALSFAEDQQLTAMEQEYNMRQSGSELLTAGSEQSTADQVGAALDGKPAQPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C844</accession>
    <name>X0C844_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C844"/>
    <dbReference type="OrthoDB" id="4096268at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051176">
        <property type="entry name" value="Cent_Immune-Sig_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 170 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715:SF37">
        <property type="entry name" value="LD47843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="39"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK90590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="691" mass="76115" checksum="6F630CFF9AFF93CF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8B5</accession>
    <name>X0C8B5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658490">
        <property type="protein sequence ID" value="EXK78952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8B5"/>
    <dbReference type="HOGENOM" id="CLU_020129_1_0_1"/>
    <dbReference type="OrthoDB" id="5423360at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058329">
        <property type="entry name" value="Arp1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26053">
        <property type="entry name" value="DUF8016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Scytalone dehydratase-like protein Arp1 N-terminal" evidence="2">
        <location>
            <begin position="62"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="213"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="649" mass="70192" checksum="B41F50F157A11670" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBK6</accession>
    <name>X0CBK6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">glycogenin glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.186</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_06280</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Self-glucosylating initiator of glycogen synthesis. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = alpha-D-glucosyl-L-tyrosyl-[glycogenin] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23360"/>
            <dbReference type="Rhea" id="RHEA-COMP:14604"/>
            <dbReference type="Rhea" id="RHEA-COMP:14605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:140573"/>
            <dbReference type="EC" id="2.4.1.186"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:56560"/>
            <dbReference type="Rhea" id="RHEA-COMP:14606"/>
            <dbReference type="Rhea" id="RHEA-COMP:14607"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:140574"/>
            <dbReference type="EC" id="2.4.1.186"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase 8 family. Glycogenin subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.186" evidence="10"/>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBK6"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008466">
        <property type="term" value="F:glycogenin glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000092">
        <property type="entry name" value="Glycogenin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="277"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="567"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="703"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="479"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="490"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="516"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="575"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="703"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="769"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00057883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK91531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="814" mass="89916" checksum="195E8C5E4B5B9EE6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE55</accession>
    <name>X0CE55_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zinc-ribbon domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE55"/>
    <dbReference type="HOGENOM" id="CLU_131621_0_0_1"/>
    <dbReference type="OrthoDB" id="4161192at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19372" checksum="44FC5173AAF3BEB1" modified="2014-05-14" version="1">MFGRRRRPILGAAVVYGASRAAAKHEVRNQELMASERDREIEREVDLRRREEEEQELRTQRAVDEAMKKAALQEQAAQQSAAAMIPPQPRYDEAYPMMQAQTRDLGVFNPVNDGNTTIQPAPAYQVGPQRGPVQGPVPGSRIHYCTQCGFGCQETDRFCRQCGAKQAAGEIVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF61</accession>
    <name>X0CF61_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF61"/>
    <dbReference type="HOGENOM" id="CLU_2263860_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="103" mass="11521" checksum="C48A5CF62186D92D" modified="2014-05-14" version="1">MDTITSFISMFVTQRQQSKPLPSPDINRYQARWAVSLKVLCIIYRSGLIPALIAIGSSSLLPIMPWSPALDFCFFGVEPVEVLALNRSKLSTNSDRDMSKTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF88</accession>
    <name>X0CF88_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979335">
        <property type="protein sequence ID" value="EXK81272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF88"/>
    <dbReference type="HOGENOM" id="CLU_007526_0_2_1"/>
    <dbReference type="OrthoDB" id="191037at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF1">
        <property type="entry name" value="HAD FAMILY PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="386" mass="43748" checksum="14B1363922DA4AC6" modified="2014-05-14" version="1">MRSHQDTEARSRHDLDDEALGSHLLSSREMPNLKLPVTTSKIGYGQSNPTYYLDDAAGVRYILRKKPVGKAISPVAHQVDREFRVLKALGSVEGFPVPRVFTLCNDSSIIGTPFYVMEFVKGRIITDTDMEELSPDERRQAWFSAIETLAWLHSLDPDKIGLEGYGKKTGFYARHCATWSRIELQQAAVKHVKTGKPLGRAHKRYDEVVRYVRENVPSDRQAIVHGDFKFDNLVLHPTEPRVIAILDWELSTIGHPLMDLVFCISPFFSDYTKSGKSSLSLQDSPYKLEHRARSGIPEPDELLARYAEIVGFDMRQDNRGKDWDTAIIFHYLRGATIAHGIQARSISGQSSSSFSHLYFSKTRQAIEAALRRIQSLKDRQTAESKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHM9</accession>
    <name>X0CHM9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxypeptidase D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHM9"/>
    <dbReference type="eggNOG" id="ENOG502RXXJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080487_0_0_1"/>
    <dbReference type="OrthoDB" id="373498at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035241">
        <property type="term" value="F:protein-arginine omega-N monomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18090">
        <property type="entry name" value="Arginine_MT_Sfm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007364">
        <property type="entry name" value="SFM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517:SF1">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04252">
        <property type="entry name" value="SFM1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="207" mass="23004" checksum="2BC689567A52D32F" modified="2014-05-14" version="1">MAASGKTFIVEHLDPELGPWSELEYLAIARETQATHGSFILSSLPSTFQVPTDLASNPAFTAEQRGVEELYAANKSRVCLLDPSAALDLSPEDGENFDAFLFGGILGDDPPRDRTSELRKKGFEGRRLGPKQMTTDTAVRVTRIVVQDKVPLDQVPYLDFPELKFNEHESTEMPFRYVQGEDGKPIMPKGMVELIQKDADKAVDDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJE6</accession>
    <name>X0CJE6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06525</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK90964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJE6"/>
    <dbReference type="HOGENOM" id="CLU_737800_0_0_1"/>
    <dbReference type="OrthoDB" id="194139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937707" description="Major facilitator superfamily (MFS) profile domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK90964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="38644" checksum="A21F4B0F777600C6" modified="2014-05-14" version="1">MPRDYLLPFLSVCLFVIQLGLSVSDLPSIKLMQDIVCKHVHRIDSPELLPEEKCRDEPVQQRLNFSMMGMQISATISATLVAFPLGVLSDRIGRLPVLGASILSMILSQSYAMFVRWKSDMIPLEAIWCIGVALLFGGGRSVAEAMVFVIIVDTWVVASGLAAQLEGPVLSGELVQSSVWMPLFLSLGLVLGGGIILVSLTPETLKLKQPREDASIGPYDYGLESNMLSLESLKRTSVMVAFKSMFSRPLLRLISVQLASQPFYTYCIFAKLGHTSHPMHTATCHHMYLEQTHTFANSSQMLKSSLREFVAILSWLPLHDDGNKGSLHHCRPGRVGTGLRSTYAMPRHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJL2</accession>
    <name>X0CJL2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Spermine/spermidine synthase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_04470</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJL2"/>
    <dbReference type="eggNOG" id="ENOG502QTVA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017511_2_0_1"/>
    <dbReference type="OrthoDB" id="2016285at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000288">
        <property type="entry name" value="Spermine/spermidine synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037959">
        <property type="entry name" value="MFS_SpdSyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF59">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK94371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="580" mass="63877" checksum="466B85FA4B6FAC12" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJY4</accession>
    <name>X0CJY4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03598</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJY4"/>
    <dbReference type="HOGENOM" id="CLU_2542676_0_0_1"/>
    <dbReference type="OrthoDB" id="10275716at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="83" mass="8945" checksum="D39C8EAD4AB6A41A" modified="2014-05-14" version="1">MADVPLAFLTPSVDSEQRHETASRIKGVFLPEQSMILAQIQGGAQHVQACPPQNYVSKNAPQRFPLGLEAVTAHNSSFLLATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKT4</accession>
    <name>X0CKT4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKT4"/>
    <dbReference type="HOGENOM" id="CLU_2722295_0_0_1"/>
    <dbReference type="OrthoDB" id="4424523at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="72" mass="8276" checksum="244C249E497DF264" modified="2014-05-14" version="1">MDPGLSLQRHRVSKSELYLLDTVLEAVLTKEEIAARQISLDMKGFWDQQSGNAKETRKDNDRQIIEEAMTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM62</accession>
    <name>X0CM62_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CM62"/>
    <dbReference type="eggNOG" id="ENOG502RJ8F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_645645_0_0_1"/>
    <dbReference type="OrthoDB" id="5093448at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="331"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="494" mass="54227" checksum="D1A3F0C1D637427D" modified="2014-05-14" version="1">MAHAEEAAASPAQPSPTPAATPAADLEEIVMPPNFTHNPKEIQSVRRYVRRIEAVIGQKPWECRNLLGDLANLLEEAIKVCDASAIKDHLHERANPPRGGQHKVLRAGDIKAAREFFGATKGANLTRSASKPAAQREDDREIGATDDDDDTMADEHSRRGGLTSILASINSRKLSDAALEHGATADSIVAANHNENTIALAESTSPEEAPATPSPLPYPPTNKRDRSISSTSVNPSNKRVCNEAASSSLQPLQPAAPTPPMMTDQHNSDDHSALIQATDAFHHHLEMHVQDLRKQHEQRLGIVELQQHHINHELEIHQPSLEAYRIAQEYSLQAEAKVENLRADNEKLNTLLKSLADSKDLWMAFSAEKFEAMEQDLVAQLAAKVSALEEAEAELSTAQLTCHQTEEAARPALEFMNKETPQLEEKKTTAERLGLYVTYTEFLQLLVRTSPSAIATFDKLLQEKGSSLQELRAVIERHGQLAQVDGQQADVPMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMF6</accession>
    <name>X0CMF6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flavin-nucleotide-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMF6"/>
    <dbReference type="eggNOG" id="ENOG502S42E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067890_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34071">
        <property type="entry name" value="5-NITROIMIDAZOLE ANTIBIOTICS RESISTANCE PROTEIN, NIMA-FAMILY-RELATED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34071:SF2">
        <property type="entry name" value="FLAVIN-NUCLEOTIDE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="29475" checksum="AABD19BFD827E18D" modified="2014-05-14" version="1">MGRHNLQYPKDSANTIKRYKVHGVYDLETVHSIVNTCPILHISFNTPSQPFPVVLPMIGQLGSFDRPSSSLRDPLELYLHGYVSSRIMNLAQTSTVDGEEIQGMPVCVAASHVDGLVLTLATYSHNYNYRSAVLYGYATTVKSDEEKLYAMELISNSVVADRWNHTRQPPLASEMQSTNILKVKITSASAKISAGSTTDDKSDLENESLVNSTWTGVLPVYQTIGEPIPGPYNKVEVPEHVSTFATDTNDEKKQRSLEAAKGERRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMS3</accession>
    <name>X0CMS3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMS3"/>
    <dbReference type="HOGENOM" id="CLU_2867695_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="64" mass="6781" checksum="8AC888FD2400523B" modified="2014-05-14" version="1">MTAGSSSVTSRELDLFVSKVCSASYTPNPAVAKPRVTTGCGPEAKQPKLQLDTEHLTDTLLFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNJ0</accession>
    <name>X0CNJ0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Purine-cytosine permease fcyB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_05863</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNJ0"/>
    <dbReference type="eggNOG" id="ENOG502QQ8Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026016_2_0_1"/>
    <dbReference type="OrthoDB" id="2116389at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF5">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK92863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="40716" checksum="0E707DC021A42F3C" modified="2014-05-14" version="1">MRQMIQARYSFGLYLGIIPILLNAGTVTGFTLVGSIVSGQAIAAVNEKANISVNVGIGIVCTLSFCLAFLGYRAVHVWQRWQWLPNLLAIVIAVGYGGKHLMNQADHDPASVKSVVGYGSLMAGYFMTFGGTVSDFTVYHDPKSSKLKIFTYVYLGLITPSTPLLILGAAIGGALPNVESWQTAWDNYGIGGVMAEMLAPAGGFGKFVLVVLALSVVGNMVLSNYSVALCLQMLVPAFAKVPRFLFIVATLAIMIPMSIYAAAKWEESLVNFLSVIGYWAGCFDAVVIEELIVFRNMDYHSYDPAIWNQVRRLPTGLAAIGASLVSIGLVVPSMDTPWFTGPIGERISDLGFESAFVVTGIAYYPLRTLEVRLMGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP46</accession>
    <name>X0CP46_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beclin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_03305</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP46"/>
    <dbReference type="eggNOG" id="KOG2751">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024219_3_1_1"/>
    <dbReference type="OrthoDB" id="20368at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043548">
        <property type="term" value="F:phosphatidylinositol 3-kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.40:FF:000005">
        <property type="entry name" value="Autophagy protein Apg6, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041691">
        <property type="entry name" value="Atg6/beclin_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17675">
        <property type="entry name" value="APG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6/beclin coiled-coil" evidence="5">
        <location>
            <begin position="149"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Atg6 BARA" evidence="4">
        <location>
            <begin position="280"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="31"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="152"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK96185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="486" mass="54230" checksum="0C3717C8CCEC8DC6" modified="2014-05-14" version="1">MNCQKCRQPLRLDGSLEDLNPAAYDVLVSSTSPQTLKKSSVTSPPITQPQEQARKSLYETVSRNTGPPTFKRNHGGHPRDSSMSFVLLSESQMTHPSQPPESHAMPTALRRASSARSSGDNVDAPVGNEMDRVNRLFEILSARSDIDHPICVECTEMLVEGLQKKLEVASRERDAYVKHLKEAKANKPSEEDMKAQEEALRKAEQDRATAMEELKKLESEKTSLDEELVALEEESRQLDKEEEKFWRERNEFATKMGEFQAEKDSINAKYSNDSQLLEKLQRSNVYNDTFCISHDGSFATINGLRLGRLSNKPVDWPEINAAWGHALLLLVTVADKLSYRFDGYDPQPMGSTSRIIRYEVPSPSSSRLGSRAVNAPPKKHVLELYSSGDMPLGLTFMHRRFDNAMVGFLELVRQLGAYVHRQTDATGTPLSLPYKIDGDKIGDVSIKLGIAQDDGWTKACKLTLTCCKFLLAHASNVTSNARNGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPZ8</accession>
    <name>X0CPZ8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPZ8"/>
    <dbReference type="eggNOG" id="ENOG502QQDH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_297748_0_0_1"/>
    <dbReference type="OrthoDB" id="2546325at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1079" mass="123440" checksum="135D4A1D89ED4765" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQT5</accession>
    <name>X0CQT5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQT5"/>
    <dbReference type="HOGENOM" id="CLU_143619_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="129" mass="14535" checksum="483A5A8F42A75B3E" modified="2014-05-14" version="1">MIIQSIYLSPTPLQSPEATPLTALLSTIINTRIKVLRRNAPASVTLQCYIATVRPPGPCAKWQGARILCYTIPYVYLFLFATDRCVSTWGIFTKHARETRGPFYCQDIQRSRSWTMHAKSCLHAVAAMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR90</accession>
    <name>X0CR90_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02333</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR90"/>
    <dbReference type="eggNOG" id="ENOG502SVPQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2038168_0_0_1"/>
    <dbReference type="OrthoDB" id="4755094at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="14398" checksum="52954E4D16D21E6E" modified="2014-05-14" version="1">MSMEHRLSSHMTLASKAKELAEDNRVLREQLNDAQSHIFSLQPYRKDLTPEEVGQDYDALVEQIQDWVQKLVNPWLEDCDDDAHAFLTHAKRRKADANGFKSVLKKEKRKIPGSYEWSEFPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRQ3</accession>
    <name>X0CRQ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRQ3"/>
    <dbReference type="eggNOG" id="ENOG502SH7R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053163_2_0_1"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08946">
        <property type="entry name" value="SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103:SF6">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="304" mass="34092" checksum="70C1D398D98E5ABA" modified="2014-05-14" version="1">MSKRIIVTGGSGKAGRYIIEYLLAQGHQILNLDLVPLPVDLSQKVHTLRCDLTDGGQVYSALSSHFRLTEPFREPINDPPDTVLHLAGVARNMLVPDIETFRVNTLGAYNIIEASCRLGVKKVILASSVCVYGVTYAEGDVDFEAFPVDESHDPNPMDVYSLSKICAERTARSFATKFDVDIYALRIGAVVCPHEYNKVFHSYVNDVEKWKVHGWSYVDVRDLGKICSLALSRDDLGYQVFNATNDEITNKRNTTELLKEQCPNIPLTRTMGAREAPISNAKIKEVLGFEADYRWRDLYNGQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS02</accession>
    <name>X0CS02_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS02"/>
    <dbReference type="HOGENOM" id="CLU_2606127_0_0_1"/>
    <dbReference type="OrthoDB" id="10274427at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="79" mass="8797" checksum="EF36ADD96776ECE8" modified="2014-05-14" version="1">MTPHISYFGDDAQLPLSKLAPVEPCLEQATLPYRSDSISLLFQPNLQILVTLSTQPRWRIDNSMNPHPSSSPVEPPIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUN7</accession>
    <name>X0CUN7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trehalose 6-phosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUN7"/>
    <dbReference type="SMR" id="X0CUN7"/>
    <dbReference type="HOGENOM" id="CLU_002351_3_0_1"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1020:FF:000003">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase subunit Tps2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000036">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase subunit Tps2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000131">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF123">
        <property type="entry name" value="TREHALOSE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK97871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="883" mass="99499" checksum="D5454C43C8AAC9E6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV91</accession>
    <name>X0CV91_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV91"/>
    <dbReference type="eggNOG" id="ENOG502T1WI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108099_1_0_1"/>
    <dbReference type="OrthoDB" id="5423884at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK98385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="155" mass="16920" checksum="F90372735E9A1513" modified="2014-05-14" version="1">MAPLSSPQDLGLGAILARALSSPTLSPPPTLVARQNTETVTVTSSGDSGNSAQTLSGGAIAGIVIGSIAGFLLLLWVVRSCLNLGAPPQEREKWYHYKEEPRRHSHHHRSRSRRSHRSSISAPPPIVVRDSRSRSHRRGRSPGYYGTDRGTRYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVA7</accession>
    <name>X0CVA7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVA7"/>
    <dbReference type="eggNOG" id="ENOG502SCDZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF3">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="876" mass="96429" checksum="BFF244422A6A9090" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWP5</accession>
    <name>X0CWP5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_03900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWP5"/>
    <dbReference type="MEROPS" id="T01.010"/>
    <dbReference type="eggNOG" id="KOG0174">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_5_2_1"/>
    <dbReference type="OrthoDB" id="7854943at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03762">
        <property type="entry name" value="proteasome_beta_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000010">
        <property type="entry name" value="Proteasome subunit beta type-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF0">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE SUBUNIT HSLV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 11 12" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK95284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="229" mass="24859" checksum="2D0A30E267578A28" modified="2014-05-14" version="1">MEFGNAGVLNEDGIHVDMDRLKKGEVNLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDTIWCCRSGSAADTQAVADIVQYQLGLFAMTNGKPPMTQTAASIFQEICYANKDRLSAGLIIAGWDERFGGQVYSIPLGGSLHKQSYAIGGSGSTYIYGYCDANWREGMEKDDAVNFVKGALREAIKWDGSSGGVIRMVVLTKDGADRHLYLPDTDYAVRHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYN1</accession>
    <name>X0CYN1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYN1"/>
    <dbReference type="eggNOG" id="ENOG502RJB5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_943466_0_0_1"/>
    <dbReference type="OrthoDB" id="5089074at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="287" mass="30899" checksum="0603E41C812940D0" modified="2014-05-14" version="1">MPTQILLAGNSTNNTTAKAQDYPIFKADKDGITSLAILAAILAFFAGIILRDLLNKRRTGEFKEDKKSCGKFFRTLFCLPCLICSKDNVRRLWIKFTNLFRSKDNQRVVKKSDQNGIEMEERLESGKSVGGFNGAWSPKKAFVSEKTQKSSKGKAIDTTVLPQVPEFSVDHNKDDEGFTSTPVHGAGTRAARNGSTEHDNTLGVYNHGDSSTEKAGSSSANHHHSAGSSSVSAGRSHWWSSGHGHGHGNSYSPSHSNSHSHDYGSHSHDYGHTGSGGFDGCDGGGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZR8</accession>
    <name>X0CZR8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08797</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZR8"/>
    <dbReference type="eggNOG" id="ENOG502SSXE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094698_0_0_1"/>
    <dbReference type="OrthoDB" id="3862662at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF20">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="127"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="159"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK87942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="213" mass="24633" checksum="CBE68E3122448509" modified="2014-05-14" version="1">MANNEASVECEQEAERQLNPIACSHCRQRKRKCDRQLPHCLQCSNDPTNCHYPEQNKRGLPIGFITRLETRLAETEEALFRLVHSIDEPNNNHTSLKPSSQRKDDRIREWDSLPLRNADEIRAWYRNRSEQTHSPAQHDDLMDEDQRTRSIHATPPEPEPVDFPDDAGDDQGETITLQDADDDVMPRNAIHIPEESGGSKAKEMEQKHPNMYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0X9</accession>
    <name>X0D0X9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 19">Mevalonate kinase</fullName>
            <shortName evidence="19">MK</shortName>
            <ecNumber evidence="3 19">2.7.1.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">FOQG_02190</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">54005</strain>
        </source>
    </reference>
    <reference evidence="23" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17065"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:58146"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.36"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:17066"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="18 19">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 19">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 19">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.36" evidence="3 19"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0X9"/>
    <dbReference type="eggNOG" id="KOG1511">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017814_1_0_1"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004496">
        <property type="term" value="F:mevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000027">
        <property type="entry name" value="Mevalonate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.890:FF:000003">
        <property type="entry name" value="Mevalonate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006205">
        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290:SF2">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 19" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 19 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 19" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14 19" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 19" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="16 19" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="13 19" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="15 19" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="21">
        <location>
            <begin position="186"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="22">
        <location>
            <begin position="358"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="10"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU363087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EXK96764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="508" mass="54936" checksum="A1F7D8E581EBEC3B" modified="2014-05-14" version="1">MPSVTPVMVNGLNGSHANGNGNSHGPASDSGSETSGDSSNGSARRRMKLNRKMSSPMAPPFMVSAPGKVIVFGEHSVVHGKAAIAAAISLRSYLHVTTLSKSKRTVSLRFADIDLVHTWNIDDLPWDAFQQPSKKKSYYSLVTELDPDLVAAIQPHIEVVSPNHPEEIRRVHHSSVSAFLYLFLSLGSPSFPPCLYTLRSTIPIGAGLGSSASVSVCLSAALLLQLRTLSGPHPDQPSEEARLQVERINRWAFVSEMCIHGNPSGVDNTVATQGKAVVFQRTDYSKPPTVRPLWDFPELPLLLVDTRQSKSTAHEVGKVAKLKQTHPKLVGTILDAMDKVTDAASELIHDTSFDSNSETDLSKVGELMTINHGLLVSLGVSHPRLERVRELVDHEGIGWTKLTGAGGGGCSITLLRPGVPTDKLQKLEGQLESENYAKFETTLGGDGIGVLWPAVLKNGTEEDDEGGMEIDLEKFLEAEGTEGVEKLVGVHGDTGEREGWKFWRVESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1Q1</accession>
    <name>X0D1Q1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleolar protein 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">Pumilio domain-containing protein NOP9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00554</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1Q1"/>
    <dbReference type="eggNOG" id="KOG2188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008720_1_0_1"/>
    <dbReference type="OrthoDB" id="392571at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040000">
        <property type="entry name" value="NOP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22493">
        <property type="entry name" value="PUF_NOP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="657"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="683"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="724"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="747"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL00342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="759" mass="84939" checksum="A996A3DF319B12D3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2B9</accession>
    <name>X0D2B9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2B9"/>
    <dbReference type="HOGENOM" id="CLU_3377138_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL00921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="34" mass="3803" checksum="36524E93C3DF847D" modified="2014-05-14" version="1">MLVNFDQDRAGINESIKFKSREAHGLNPGNSKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4X8</accession>
    <name>X0D4X8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7703 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4X8"/>
    <dbReference type="eggNOG" id="ENOG502SMNP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045148_3_0_1"/>
    <dbReference type="OrthoDB" id="405906at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056120">
        <property type="entry name" value="DUF7703"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24802">
        <property type="entry name" value="DUF7703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7703" evidence="3">
        <location>
            <begin position="22"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK98633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="353" mass="39446" checksum="AFA7F8F5547DDAC2" modified="2014-05-14" version="1">MSLSRRTDAASKFTSSGRYTPEAMIVITCATISLYNGIELLLLILTSSRRHNDLFSWSLAVASIGVLPYASGWLVRYFDVIGDVANMLINDIGWILLTTGQALVLYSRLNLLFKSITILKVTKWMIILNAIIWHSAVTVLLFAISTQQKLDRNGAFIKVQKVQLAFFCAQDFLLSGLYIWKTMEIIKRKEAENQTPRIIWHLFAINVGIVLVDVTLLAVSFTNNFLWQQGIKAVAYSVKLKVEFVILGKLSDYVHKGGELISAEHPVFGFVEMEPEPPSRKQSTQPSATPDATHLERVRKQSTISAAESSRNREFMSDEIATDRSEGVKRRTLGKGKSKCMDDCCNTGVSASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCB9</accession>
    <name>X0DCB9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ELMO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_00772</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCB9"/>
    <dbReference type="eggNOG" id="KOG2999">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009191_0_0_1"/>
    <dbReference type="OrthoDB" id="28413at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017124">
        <property type="term" value="F:SH3 domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024574">
        <property type="entry name" value="ELMO_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11841">
        <property type="entry name" value="ELMO_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16457">
        <property type="entry name" value="PH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="2" id="KW-0581">Phagocytosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0729">SH3-binding</keyword>
    <feature type="domain" description="ELMO" evidence="6">
        <location>
            <begin position="259"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="267"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXL00755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="715" mass="80018" checksum="2AFAEAE7AAF0A03C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0DG05</accession>
    <name>X0DG05_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Delta 8-(E)-sphingolipid desaturase</fullName>
            <ecNumber evidence="5">1.14.19.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_04711</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.18" evidence="5"/>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DG05"/>
    <dbReference type="eggNOG" id="KOG4232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="260091at2759"/>
    <dbReference type="UniPathway" id="UPA00222"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF30">
        <property type="entry name" value="DELTA 8-(E)-SPHINGOLIPID DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="8 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="18">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="103"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK93417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="550" mass="62959" checksum="844F56EC2C4A7405" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DGI1</accession>
    <name>X0DGI1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DGI1"/>
    <dbReference type="HOGENOM" id="CLU_2210118_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="107" mass="11910" checksum="B84673B805275EBE" modified="2014-05-14" version="1">MICTVLSAQSESQLSSVIQAKAIAELSNIGTVPILCYDYTFELSHYITDDQLTRNHLLDSPSQVHHQKHIHIKITIQPQALNPRSLSPPENQLISNAQTVILILIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0DLM6</accession>
    <name>X0DLM6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DLM6"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13672">
        <property type="entry name" value="PP2C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="100"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="412" mass="44303" checksum="597C81DB5F870B08" modified="2014-05-14" version="1">MAAPYNRLATASLRTLAKGWSHCPYNTRQSAILTVPAPTQSCSRLRAYPHVAMSSCPRSRLYSTSTDAPRFSYHVASSFIAKDRPYDPSTHVFHFNPYNRIQPPRNRRPSARPESGHDAFFVSRINDSGSVAFGVADGVGGWVDSGVDPADFSHGFCDYMALAAHEHQTNSGPPLTARQLMQKGYEAICNDNSLRAGGSTACVAIAGADGNLDVANLGDSGFLQLRLNGVHTYSEPQTHAFNTPFQLSLVPPSVAARMAAFGGAQLSDLPRDADVTQHALRHGDILVLATDGVLDNLFNQDILRIASRVLVSTGAWVMTDAGGVRVADSLEPLVEFPEASEGKRTATLQSALATEIVTAAKRASVNTKLDGPFAKEVHKYYPQENWHGGKVDDICVVVAVVNETTPAVKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B274</accession>
    <name>X0B274_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658751">
        <property type="protein sequence ID" value="EXK76185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B274"/>
    <dbReference type="HOGENOM" id="CLU_2250290_0_0_1"/>
    <dbReference type="OrthoDB" id="5107616at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="104" mass="11921" checksum="A7E3CC454E92A5F4" modified="2014-05-14" version="1">MQLNDFKYTGCLLAFALITYAIEYTCRKLLFFFRLALVFASFAVMTKQRPATQQIKRWLETAGIEEIPRMALFKDIQKVATTGLQAVTMLFERGGAQDTSIKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4F7</accession>
    <name>X0B4F7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CSC1/OSCA1-like 7TM region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979423">
        <property type="protein sequence ID" value="EXK77025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4F7"/>
    <dbReference type="HOGENOM" id="CLU_2885892_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="63" mass="7047" checksum="25C3247B4AA53F8D" modified="2014-05-14" version="1">MAVISIVCSVIAPFVRFWSTIGVGLFYLAYRYNVLYVAEAEIDTRGLIYLQALKQLLSGVYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5U1</accession>
    <name>X0B5U1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658636">
        <property type="protein sequence ID" value="EXK77146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5U1"/>
    <dbReference type="HOGENOM" id="CLU_037030_1_0_1"/>
    <dbReference type="OrthoDB" id="5131365at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="433" mass="49074" checksum="A5AA1E53A605DD96" modified="2014-05-14" version="1">MNDDDSDLFSWATDDEDANHELTSQSAAICDATPLGQIRHGRSRLSLLQLAEWDETLAYDEQPPTCVHYLIEWKVKLNNRCISKDTEPDVVLAPGAYWTKYLWSKVDKLAKKKLPANRIFHVDDIDITVCVNYKGEADLNTRSDGLDVNWKMIESKLQAWSHLLLDGKKLKISLSFNYIETSQSGSVVARGRGGRSATASQLAERAIDIGEEETASAEPAVWRKVYDFFRCTGSPCGLGPHCWVDTVGKKHYKLKTHHLRALIEHVRLGNTVDSHDDVPPDVRDLLYAEEEQSIQRKRKRRSSSTDARPVNITNVMPTRTGHSSDDNDTRTPSGSAEGSRYAPKYLGIPGMRDVNVNKYCIWHCSKNANNVWKMEYKKACDLTLAEGLDLEQIRLDQDAQFFIDKGVKKGIAKRWVSDVEVWFRDVETLEDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6I9</accession>
    <name>X0B6I9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Asl1-like glycosyl hydrolase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979377">
        <property type="protein sequence ID" value="EXK77730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6I9"/>
    <dbReference type="eggNOG" id="ENOG502S2W1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040908_3_0_1"/>
    <dbReference type="OrthoDB" id="43654at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071966">
        <property type="term" value="P:fungal-type cell wall polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000207">
        <property type="entry name" value="Glycoside hydrolase family 128 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF3">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935550" description="Asl1-like glycosyl hydrolase catalytic domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="2">
        <location>
            <begin position="40"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="341" mass="37430" checksum="A197036845B5F147" modified="2014-05-14" version="1">MLVQSSLVALALFATSCIAISKNFYPSSKRGLIYIPNSDFSSDDKVWVQKHSDLTWYYNYKMHPSPVYENSTSLQFVPMLWGAPDGFDDTTFLENVTAQIIGGRNITYVMGFNEPDNSMANGGSDMKPKDAAKYWIKQLEPLRKLGVSLGAPAVTGAPSGFTWLAEFVEACKGNCTFDFIPIHWYGSFDGMASHIAGVLDVFPNKKIWVTEFALDFSSLAATQDYFQTSVKYLDGNKNVTHYSYFGSFRSFTSNVGYNVSMLNSHGQLTDIGSWYLGGDATGVIPGDNVVKPNVTAAKPSTSTYVVPALVTEDSDSLGLMNRPSIPYLGLLCPLLALYITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0B815</accession>
    <name>X0B815_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secondary metabolism regulator LAE1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979373">
        <property type="protein sequence ID" value="EXK77916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B815"/>
    <dbReference type="HOGENOM" id="CLU_010595_1_2_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="37065" checksum="E1BB9D4FEE9D55B2" modified="2014-05-14" version="1">MSAAAEVEVDDYENESGYGDEFSVVTASIDSYILRYEQKHGRTYHSYHQGSYNYPNDEQEQDRLDLVHHAFRLVLQDRLFLAPINLNSSDLRVLDIGTGTGLWAIEFADENPQATVVGVDLSPIQPGWVPPNVQFYVDDVEEDWDEPKHYDYIHCRYMAGAIADWPALVRRLYDHLNPGGWVEFQETINTLYSDDGTLEPNNALVGLMDNLKKVHDKIGRTLDPAPEFKNWVWEAGFHNITEQRFKFPVGPWPKDRRLKEIGACLSMNFTSGVDAFTAKPFRDHLGWSQKEVEVLKAEVRKAAKRREVHAMFHLVVVTAQKPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0B882</accession>
    <name>X0B882_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6603 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16978</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979362">
        <property type="protein sequence ID" value="EXK78345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502R9QD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001050_1_0_1"/>
    <dbReference type="OrthoDB" id="5352492at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052159">
        <property type="entry name" value="Competence_DNA_uptake"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046538">
        <property type="entry name" value="DUF6603"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30619">
        <property type="entry name" value="DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30619:SF1">
        <property type="entry name" value="RECOMBINATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20248">
        <property type="entry name" value="DUF6603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6603" evidence="2">
        <location>
            <begin position="1498"/>
            <end position="1970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="2237" mass="245882" checksum="E3C85C673134DE19" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9E5</accession>
    <name>X0B9E5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_16597</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979353">
        <property type="protein sequence ID" value="EXK78745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9E5"/>
    <dbReference type="HOGENOM" id="CLU_000315_2_7_1"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF52">
        <property type="entry name" value="SINGLE-STRANDED DNA-DEPENDENT ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="83"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="391"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="473"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="617"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK78745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="639" mass="71786" checksum="1AD210B2A1D582CD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC00</accession>
    <name>X0BC00_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979348">
        <property type="protein sequence ID" value="EXK79311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC00"/>
    <dbReference type="OrthoDB" id="3220769at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="497" mass="55505" checksum="F49701AABF238E68" modified="2014-05-14" version="1">MHSSWFSYPITRPFPFRWFTPVAIVGGLILMVLFTIINLASSAFYLKPIFTDDPNGTTTQSVRWFMKAPLNWDNNMKVKCQPKILSVGDRVFSTNLGFQYSVKALTSSDDDSDFRKTYPSIAYLNNTLEDCYLTRVDINLRKSDARASNSWWLSWITTFTDATASCNVMTSEGLVNITLGVEYIGQSDHIYDYVIEDDYKTHASTWWGTRLLNVYFTGILSTMSQTQYLGDDSYWMTGGITFTTNPNIKDIRDPKLFNLAGWFLSSDGFIQNEPLNDTSFIKTDPKNQFVPVVWESLHYTRILHSLIAVDLGNQNAPNLLLDKKDLQYAILPPDDPNRKNGSFLNDSSLTGQATRYAQIPTPGAPLPPTDKNLVLLNETYDRFASEMGPLECNTATVVSQYLCSVPQSKSPGIMLLAILLADLVFLQAAWVIYNWIAGSMLSESQMQTCQGCVESPVQVIEKEGLLGEGKTTVTSGSYVSVSADEGAGSNLLIREAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDS9</accession>
    <name>X0BDS9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979428">
        <property type="protein sequence ID" value="EXK76978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDS9"/>
    <dbReference type="eggNOG" id="ENOG502S00D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052989_0_0_1"/>
    <dbReference type="OrthoDB" id="5233393at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052998">
        <property type="entry name" value="Hetero-Diels-Alderase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060:SF1">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936260" description="SMP-30/Gluconolactonase/LRE-like region domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="35965" checksum="631D67018785715E" modified="2014-05-14" version="1">MLFHSVLSLIAFPAVALGSSFTAKTIGQLPLGTWLENVAVRSNGDLLVTELWPSATVYTVANPADCKSGLEELVTFPSITGLLGIAEVPKSPGKPETFIAVGSEATALSHLTPGTFEAWAIEFPNRRHQPKVKVRKISDMTKKSAFLNGVAAIPGRSDAVLVSDSVAGFVGRLDLSTGVFDDSAFVFPEMAPISADAFGINGIKVRDSYLYFTNSNAVKIYRIAITPAGYPKKGAKPQLVADLSSGVGFLDDFEFDTNGNIYAATNFDNSIVFVDVKTGKWRTVVGGIHEMTVAGSTAAAFSYGKKGEKTLYVSTSGALAKPVDGTKTEGAKVVAVRIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGJ3</accession>
    <name>X0BGJ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">agmatinase</fullName>
            <ecNumber evidence="4">3.5.3.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_17706</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>agmatine + H2O = urea + putrescine</text>
            <dbReference type="Rhea" id="RHEA:13929"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="3.5.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="5">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.11" evidence="4"/>
    <dbReference type="EMBL" id="KI979382">
        <property type="protein sequence ID" value="EXK77599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGJ3"/>
    <dbReference type="eggNOG" id="KOG2964">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_1_1_1"/>
    <dbReference type="OrthoDB" id="288726at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033389">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via agmatine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019627">
        <property type="term" value="P:urea metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11592">
        <property type="entry name" value="Agmatinase_PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.10:FF:000006">
        <property type="entry name" value="Agmatinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF30">
        <property type="entry name" value="AGMATINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938495" description="agmatinase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00050304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00066392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036979-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK77599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="386" mass="41797" checksum="DE3206A39F0A75B7" modified="2014-05-14" version="1">MLYKSLVSLSLASVALAHGDHGHDQEPMSGPHQGLWYNTLPGDGGTQADSVFSGISTFGRLPYQPCLKANSIKYDIAFIGAPFDTGTSYRPGARFGPSGIRQGSRRLNLYGGYNVPLATNPFNSWATVLDCGDIPVTSYDNQWALRQIEEGHYNILSRPPATDADKSGPALKSRTLPRVITLGGDHTITLPLLRSINRAYGPVTVIHFDSHLDTWKPKVFGGSPSEVAAINHGTYFYHAAMEGLLRNDTNIHAGIRTTLSGPSDYDNDGYCGFEIVEAREIDTIGTDGIIEKILKRVGTDRPVYLSIDIDTLDPAFAPATGTPETGGWSTRELRTIIRGLESLNLIAADIVEVAPAYDTNAEHTTMAAADVLYEVMSIISVSNRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH35</accession>
    <name>X0BH35_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH35"/>
    <dbReference type="HOGENOM" id="CLU_927635_0_0_1"/>
    <dbReference type="OrthoDB" id="3836772at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39602">
        <property type="entry name" value="ACW-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39602:SF2">
        <property type="entry name" value="ACW-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936932" evidence="2">
        <location>
            <begin position="23"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="298" mass="29994" checksum="EB79EDE5A99D680A" modified="2014-05-14" version="1">MVSNTRSVIFGLMLSAAQLSSASPAAASDTAFSSPIYPTATDSIPPLPSSTDECLAKCNEARDKCNTAPDANHATCAANYAECVGYYPYDKKGTYVPPTACSHSSKPTATETAKADECVEKCDKAHDACNTAPDANHATCAAQYAECLGYNPYDSGSLVAPTACSHSAKPTGTHSATATASAHADDCLEKCNKAHDACNVAPDANHATCAAKWAECLGYNPYDGPGGSLVEPTACAAATTMASATGKHTGMETSKPTSTEASKPSKSEPAVVVNGAGSLSGKVAGLAGAIGAAAVALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-10-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJC2</accession>
    <name>X0BJC2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6603 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979355">
        <property type="protein sequence ID" value="EXK78564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJC2"/>
    <dbReference type="HOGENOM" id="CLU_1875540_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046538">
        <property type="entry name" value="DUF6603"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20248">
        <property type="entry name" value="DUF6603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6603" evidence="1">
        <location>
            <begin position="2"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="15420" checksum="B5A35EBCAE796AFC" modified="2014-05-14" version="1">MFTASGGINVGVRYTLDLWFVTIYINIQVGATLFLQGPPFQGVCHVNFWVFGFDIAFGPSDAVESPAPIQLLEFYRLTLQMQTATEEDSLKPHIFTCNFGLVSSMNRNRKTPRRLPKCPMILLRILILHPQYGQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJD6</accession>
    <name>X0BJD6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658489">
        <property type="protein sequence ID" value="EXK78988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJD6"/>
    <dbReference type="HOGENOM" id="CLU_064344_0_0_1"/>
    <dbReference type="OrthoDB" id="4922812at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="345" mass="38554" checksum="7E766C2C8CB958B9" modified="2014-05-14" version="1">MEDKGGSGNPAWQQQWVEWTNVLPSSNTQCLLICLGYVIIFAYHGHSHTEKSLALALHILAATFEPKRYYLPSSNTQYLLICLGYVIIFAYHTRHSISAYYGHSRTEKSLALALHILAATFELTRYYFRAFRRTVQPDLFDTAACMIHSITSLRLARTLRRGDKTTRASYQAPAMLRPVLSFAAVVRQDAFAHEACVKLLHAFLYTRLLIFVAKRIGLGKIQSHSTIYARAVTLGAILAIRSSGLPAGVPIYVGAVGLVMVFNQQTPSNLPSSVHLMDGIERRPGTRVIRSTSVKRTKEKVEQAVTKVIQWLGLFEIKGFEMKHLSPTIPAGDIDEYTEQKLAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJM0</accession>
    <name>X0BJM0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrogen regulatory protein areA GATA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658511">
        <property type="protein sequence ID" value="EXK78654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJM0"/>
    <dbReference type="eggNOG" id="ENOG502QSII">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020417_0_0_1"/>
    <dbReference type="OrthoDB" id="5563539at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052292">
        <property type="entry name" value="Glucose_repression_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051:SF1">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="457" mass="51745" checksum="48408F668CC34BF9" modified="2014-05-14" version="1">MFSSIAQEKSYFHEEIDTDNNQETFSSFRSGSSYTISTEDHATSKLSNGILKPGAPEDSECTKDDMAVSSRPSHQVDYLSHDWREEDIWSSWRYVVMRRGDLSDSERLENAVWRTWIKAKYDLTTISPETLNWLKDHDVTWLYGPLHSVPNPFDTTQNELSEVPLPKTDSHVKLDRKPILKKRSMSEEILQRSLSTASISKQARAACKMQETGDCTHISFLSTEDLYLPFSRESSGTISPNGERKRTHFNEQVEQCIAVEVEGIHNDDNDPDTGRYGDDSDPDDGVMVKCRKTRTWPLFERDTPESKLAEGKTIAMLPSTTIKNWEDYPEQGGTASKHSRSPFMPSSSEDNHRPAKQTQIFVVEERDQDSVDDARLSPCKSWPPSPAENTTSGIPSWLSSNSLCEEPVGMRITPSGMLMPYEEEEIPSADGILGRIIDTVKTARDIAHVIWTLGWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJR1</accession>
    <name>X0BJR1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658482">
        <property type="protein sequence ID" value="EXK79118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJR1"/>
    <dbReference type="HOGENOM" id="CLU_015936_0_0_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391:SF7">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="596" mass="67227" checksum="F7C6393D90B062E5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLQ4</accession>
    <name>X0BLQ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_15609</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the nitroreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658458">
        <property type="protein sequence ID" value="EXK79823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLQ4"/>
    <dbReference type="eggNOG" id="ENOG502TE3U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073125_0_1_1"/>
    <dbReference type="OrthoDB" id="2138173at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02140">
        <property type="entry name" value="Frm2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.109.10:FF:000001">
        <property type="entry name" value="Nitroreductase family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="entry name" value="NADH Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033877">
        <property type="entry name" value="Frm2/Hbn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43035">
        <property type="entry name" value="FATTY ACID REPRESSION MUTANT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43035:SF1">
        <property type="entry name" value="FATTY ACID REPRESSION MUTANT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="FMN-dependent nitroreductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="7">
        <location>
            <begin position="9"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="201" mass="23003" checksum="DC29C0421B66B813" modified="2014-05-14" version="1">MADKYLAEIKSRRTCYSIEAKSPISDARIIEIAQEVVKHTPSSFNCQSTRLVVLLKEEHVKFWDMATECFKATMKSGIFAEYEKKLLQRRAGYGTILLFEDLDVVREYQAKFPRFATHLLQFSEHNNAMQTLNLWTALSLEGLGCNLQHINPIIDQTLIGEWDISPQWSLKGQLVFGKPTGGTLHDKTFLPIEDRLFVHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLY4</accession>
    <name>X0BLY4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658468">
        <property type="protein sequence ID" value="EXK79494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLY4"/>
    <dbReference type="HOGENOM" id="CLU_1004883_0_0_1"/>
    <dbReference type="OrthoDB" id="2580841at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019268">
        <property type="entry name" value="DUF2278"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10042">
        <property type="entry name" value="DUF2278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="277" mass="30603" checksum="07A2141C4CA96B02" modified="2014-05-14" version="1">MPLSHPYVVWKARPVEWNMSEARGGDLRSPRGTLSFVGGNGCHKIEINVRSRDTMDHLLIFWTGKLTNETQFGHRIVQALENIGGFSYHQNPPRLDFFRDGFLNIRAGTIHDTNVEGPKNDITDDLDAFFQADLADFERSTLFVWGELIGHGSIHQVHLNQGNYPETAIGTYFFIAFAGQAFETDNNGNLASGDATAMLRDFINAPPPVTPTIPVTPGQASGLWIHSTLVNPEAYLANNRDGVIVLKAVEGAEVHRVSYSSNVPSGRWIFGPTRSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM85</accession>
    <name>X0BM85_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658404">
        <property type="protein sequence ID" value="EXK83275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM85"/>
    <dbReference type="HOGENOM" id="CLU_177978_0_0_1"/>
    <dbReference type="OrthoDB" id="5071263at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="113" mass="13093" checksum="6E9C576F5AA86759" modified="2014-05-14" version="1">MSRYFSSTARSFIRWLGFPKESLTDGFKEAVEFYSENGARKKVGEIESIEILHRNDGSSPIHQSHYNRNDREFIISARITPADGSRPKTHHIYQNGTGTFRVGDQREYSTHRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BN58</accession>
    <name>X0BN58_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BN58"/>
    <dbReference type="eggNOG" id="ENOG502T0MH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139303_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936548" evidence="1">
        <location>
            <begin position="19"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="118" mass="13054" checksum="AE3F2EE8AD42AAD8" modified="2014-05-14" version="1">MHFATIIATAALVMGVTAEPASKDLPFNVISARIWSSKDCGGDNNNGNLGELTTHRDELNECFKFTDKVKSVSQYEHAKGCKLLLFTDSNCKRGQKTVKDDQCRETSSHFSSYKTVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR21</accession>
    <name>X0BR21_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR21"/>
    <dbReference type="HOGENOM" id="CLU_2849751_0_0_1"/>
    <dbReference type="OrthoDB" id="2152029at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="64" mass="7001" checksum="2F47BBAAF59BD0E7" modified="2014-05-14" version="1">MPSRGPELSYESSPDTKMPGVPCPECTTAEKEVWVIPGHSCPYCGMVIHVSMNSTVSIFNTVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR51</accession>
    <name>X0BR51_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979332">
        <property type="protein sequence ID" value="EXK81388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR51"/>
    <dbReference type="HOGENOM" id="CLU_066261_0_0_1"/>
    <dbReference type="OrthoDB" id="4500473at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="286" mass="31125" checksum="550673DBE6E5B1B8" modified="2014-05-14" version="1">MHFGSSGTTKTETLRSTESNFDWNNANDVSHTCERLDTYSIEPTDDYVKDSVKAVASEAVKRRQRLFMVTGVKIARGAVGSFSSLRRVGGGARAGFGGESLGVPFDGGPQFTISKDIYDEETYGESSDFVFAYRVRRIVYPKGGWESMQAGSSIVNYGRCKTDAGASVAIGPSAWPFNSRLELSECDEAEIPGPLLVVYPSTWQDVCESESKGSVHDGRTEHKVAVFPEVSDYARSSGVGNNVSSEIDGPILGDARFVLEEFGHEASSIPFVDDSWEDGLFISFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRJ2</accession>
    <name>X0BRJ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRJ2"/>
    <dbReference type="eggNOG" id="ENOG502S67X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041445_0_0_1"/>
    <dbReference type="OrthoDB" id="3205825at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="41924" checksum="8BD060138BBFA3AC" modified="2014-05-14" version="1">MSATTSDIKIASIAMGFTLGFGLLTVWEAWKQTRRNRNPLRSTYIYMLWGEILANIIIAIIGWIFLDGIIGPTVPVLFFILFFWVFEVQLLMQIIVNRISIIAEHRSTIFKLKWGTALTITLINIAVFAIWIPAHTVPPASQTFVRINEVWDRVSKVLILLVDAGLNWYFLRTVKKRLVEQHRLKKYEPLVGFNAKLMIISILMDGMLIGLMSLPNQVVYIQFHPVAYMVKLNIEMSMAKLITRLAKGENADDYYPSMSHSGHHQSNNQRTNDAPWTQGNNVQLTHRSKVVAGDSDEDLSGTVGRHNGGPGIHRRTEFEVTVETKPQKNPFREGTESLDELPLTSNTGHPKQAIVEEVSRNPSMSSSRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRM5</accession>
    <name>X0BRM5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658425">
        <property type="protein sequence ID" value="EXK81578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRM5"/>
    <dbReference type="eggNOG" id="KOG4754">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039184_1_0_1"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07040">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF54">
        <property type="entry name" value="PHOSPHATASE SPAC5H10.03-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="31152" checksum="0BB8382EF46B767E" modified="2014-05-14" version="1">MSGKIIIHAVRHAQGYHNLGEEFFHLRDPALTPFGQQQCIERRKASFQDQSKFKLIASSPMMRTLHTTSLIFDDAIQTQDILAIPEAQEISDHGCDIGTDPALLREMTLRNEWPVDLSLVPEGWNDKNLYGPNSPVTGACAARARTVRRILREKGMALSRDTNDDIHIALVAHGSFMHYFSNDWENSTTGCGTGWKNCETRRYVFQNDDWDENAWLVETEESRSARGMKGPAPSAEEQRKLYEKTMVGWVDQGLPDIRYLETASVMPMQEHSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS47</accession>
    <name>X0BS47_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658423">
        <property type="protein sequence ID" value="EXK81733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS47"/>
    <dbReference type="eggNOG" id="ENOG502T46X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2171286_0_0_1"/>
    <dbReference type="OrthoDB" id="5093794at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="117" mass="14314" checksum="FAC54382E1B8C477" modified="2014-05-14" version="1">MPNKNYPHVLDIYAFKIHGKAVKETKKQLHKVEFERAKLELDGEYAEKEIKKLERVEKGLEKSRRKVDESEIKEDIRELRMELRNLNMEKENRDREQKNLKETKKRHRKSMAKLQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS99</accession>
    <name>X0BS99_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyruvate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_13865</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2-oxocarboxylate + H(+) = an aldehyde + CO2</text>
            <dbReference type="Rhea" id="RHEA:11628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="EC" id="4.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JH658422">
        <property type="protein sequence ID" value="EXK81793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS99"/>
    <dbReference type="HOGENOM" id="CLU_013748_0_2_1"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004737">
        <property type="term" value="F:pyruvate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000949">
        <property type="term" value="P:aromatic amino acid family catabolic process to alcohol via Ehrlich pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02005">
        <property type="entry name" value="TPP_PDC_IPDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07038">
        <property type="entry name" value="TPP_PYR_PDC_IPDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000019">
        <property type="entry name" value="Pyruvate decarboxylase isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000024">
        <property type="entry name" value="Pyruvate decarboxylase isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012110">
        <property type="entry name" value="PDC/IPDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047214">
        <property type="entry name" value="TPP_PDC_IPDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047213">
        <property type="entry name" value="TPP_PYR_PDC_IPDC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452:SF11">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036565">
        <property type="entry name" value="Pyruvt_ip_decrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="15">
        <location>
            <begin position="6"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="13">
        <location>
            <begin position="205"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="14">
        <location>
            <begin position="413"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR036565-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK81793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="583" mass="64272" checksum="D9A28858DFA31173" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTG5</accession>
    <name>X0BTG5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTG5"/>
    <dbReference type="eggNOG" id="ENOG502T26Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057358_1_0_1"/>
    <dbReference type="OrthoDB" id="2498029at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="277" mass="30712" checksum="5278D1275A2CB50A" modified="2014-05-14" version="1">MSEVPIDEEKLLYFEERNNDQNESIVFLHGGGGSHVEWKLVAPQQSLSSYHLILVDLPMHSGSWDIGRPLTLASAADEVCKVIQKHTHGGKAHIVGLSLGGFIALALTSRHPDVVLSTFATGAYPYRGMFKWFMEHPMAMSIVNSIQSIPGVLEASLRRQGIDYEEWLAEAKKNHSPERSKAMNKELSAFSMEDIKAVADSGVRTCVISGGKMDQIDPVRDMGVILREGGQKKGVKNEAVVVRDAYHPWHLQLPELFAAGIAAWVQEKELPEEFEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUZ1</accession>
    <name>X0BUZ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658415">
        <property type="protein sequence ID" value="EXK82324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUZ1"/>
    <dbReference type="HOGENOM" id="CLU_002639_2_7_1"/>
    <dbReference type="OrthoDB" id="5347061at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="256"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="490" mass="55264" checksum="24EB03D4A993C4C8" modified="2014-05-14" version="1">MASEESAPPKTVLVFSTKSPEEAAIFGLRGSDIQNLRAEPVPGPPATPDEWGFTSPMADGICKYCQLMLHPDPPQLIQHQPNVMHLINSGDTCSTCKWLEISIQRGAASVLAEFQRGNPELCDENNFSRPVTVELTKHEKYIMAVGWVGDRKLYTNGGVPLTISSPSRLGSLATRRFWIPHYELDESEPFKRQDTLKMWLKECESHEQCIKSLHNTKEAKLPTRVLDLTGSSDIPSDPNDIKIKLRETEEGETGTYTALSYCWGANPDLHFKTTSENLQKHKEGISFFDLPLTQRETILATLYLGIRYLWIDGLCIIQDSRQDWEAESVKMGSVYTNAHLTLAATSSDTPDMGLLLPFQGAECVKIHGETVSVRMETHRELDRMSEPLNTRGWTLQEAVLASRIVCFGKEQWLWKCPSRYATEDGLIDGSRDIDGGLIQWADIVQQGPGEDGKNYLRHWYQMVTNYSNRDLTYQSDKWNAIAGLTDMFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWZ4</accession>
    <name>X0BWZ4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWZ4"/>
    <dbReference type="HOGENOM" id="CLU_045009_0_0_1"/>
    <dbReference type="OrthoDB" id="3643156at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013243606" evidence="1">
        <location>
            <begin position="16"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="385" mass="42085" checksum="6237254573C5335E" modified="2014-05-14" version="1">MRLALLFILISGAKASGDYFEPFPTCADCLPASIHDAPGIGFSLSLSSGTAAVHFYNGTVKNIASIPANPEYAALMKRLANSPPPPPLSRWEKLRRSFNKKIGRPATPNVGIIATILVSLRDVTSIAVTSPMDRVAVSHPRIQGLAESDLWDALEYAHIRPWVAAGLPRPKVVLPLPAAGGYPSQLLESYAVFAGHGKGLCKHYKNFWQCAEEQDNVPLETTLVVGITPTDLRGEIIRTRSAFTDLQPRHGDRAFVDLELGLATSEDNPDFWARVTERLQGFCGIVPEGFRLDTILLTGENATHPAFLQALRSALVGNGFLQRESDSGEKISFVHEGGAVIDPVFASARGAAQYARWRQEAPIGCEEQDRCEEERRRQGKHVELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BY85</accession>
    <name>X0BY85_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_12180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BY85"/>
    <dbReference type="HOGENOM" id="CLU_044876_1_1_1"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF7">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="20"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK83479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="338" mass="37487" checksum="1AC37766A1E7DD13" modified="2014-05-14" version="1">MSTQQFAKDQPEGFSNRIERVAIVGAGGRQGAQITEQLLKTGKHTITALTRTGSTSKLPDKIKTIPVHYEDEESIASALKDQQLLIITLAVNVHPEVHHRIVRAAGKAGICYIIPNIYAANVVIENQGSVDDFFPAAPPINLLREIERVGVSSWILLVGGVWFDYSLPSGESFMGFDIDNRKVILFDDGEARINTSTLAQFGRAAAAIASLKEFPDNEDDKSLSIAQFRNKPVYLSSFYISQKDILRSIQRVTNTTDAEWEIKYESSADRIENGKAMGRSGNIMGLVQAYYSFILSPEGQKLKTQSKLHNELLGLPEEDLDEVVKDCVEKAENKFRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYL3</accession>
    <name>X0BYL3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ketoreductases</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_12131</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYL3"/>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_1"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937275" description="Ketoreductases" evidence="5">
        <location>
            <begin position="19"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK83609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="33223" checksum="18AEF95E77C434C4" modified="2014-05-14" version="1">MPQLVWLVTATTSGLGAAVVQNLTARGDKVIATGRGATERLKHLQSDDVYLLDLDVTAPRAEIDEQVKRAWDVWGRIDVLLNNAGISAPKSIEEADDDFVRNVFDVNLFGTVHVTQAILPYFRAQQSGTIAFIGAGVGWGPLPFLGHYAASKAALGAFVECLAKEVRRFNIRCIIFEPGGFPSQLGQPREGSVEGFGKYKPAIDAYNPGFEELMDVFISDIGPNVPGDISKLSERIVDCVKVEGASAGRPEPVRVILGSDALRLIEQKCKEQLELASSWEDVSLSTDRDGHDHVASKGMLRFSSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYX2</accession>
    <name>X0BYX2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYX2"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010578_0_0_1"/>
    <dbReference type="OrthoDB" id="42889at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF146">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="51607" checksum="5C10BC1F102DC3AA" modified="2014-05-14" version="1">MTSSEHASALSKWAHSQGATINPSVEVTHLPETGLSFRAKAPTAPFDTIVSIPSSLTLSYLNTLPGRDDPKPFPAGFLAQTPPHVIGRFVLIKHFLLKGESFWAPYIQALPQPDDHDSWSLPPFWPDEDAELFEGTNIEVGVTSIRANVKREFKTAHDLLAAESWELELLKQFTLPLYQWAYSIFSSRSFRPSLVLGPEDQQRLPEGVKLDDFSVLMPLFDVGNHDMTTKVEWVRNERINGCSLKVEKAYQAGEQVFNNYSMKTNAELLLGYGFMLPETEELHNDYVHVRKRQPAHGEATEEYYISLRPIRDPSSLLARSKQSVQLNDGTPILGAFQHVQHDMVWDIFCTLAPPEQRSTLISEGTEQEQQEKFFSGQVSEDGRMFLQQTAAIIQHKVMQELERLLETDVEVVGGGDLTRNQQLALDYRARCRRVLENTLEAMNMEELFGEDEEGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZK0</accession>
    <name>X0BZK0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZK0"/>
    <dbReference type="HOGENOM" id="CLU_036096_2_0_1"/>
    <dbReference type="OrthoDB" id="3469225at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="40550" checksum="40905A65727F4965" modified="2014-05-14" version="1">MSARTSSMLHFLAVDQEAPVCKLMRELCFALAFADDSAMHLVLARLEIDPERTGGQASQESASSLTHYNASIEILRNQLGVAQLMAHEAIIGVVVNLACYDMFTNNLTRWKTHMSGLQKMIEYRGGVNTLSSQYLQVTTIWMDLTGSMILDQPPHLALYQADLEDEAMDFVQKSHRDTEVLLELLLKLSNLAAGKSEHDLSEDSALLEELQVGVYKTLTLPRYNSPNIDQNSLTPCLLTYEIFRLAVLVYLSGPVTFLAGNRTFNVVTPHLRGRLSRMYREHRLDWTGLEHAELFTLVIGALTEVGQDRQRLIVQIQRTMRVQGLTWNGLVDKLRSMAWVDIVWSAGLDRLHVDLAFMTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0Z5</accession>
    <name>X0C0Z5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0Z5"/>
    <dbReference type="HOGENOM" id="CLU_065839_0_0_1"/>
    <dbReference type="OrthoDB" id="3596450at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="4"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="332" mass="39219" checksum="4B638E220D12A9B5" modified="2014-05-14" version="1">MASFRRFAELPKELQDQIWSLAIRDDHPGVHIFGRYDKSKKNTSESRFLRWDDIRSKTWAAPSWQRYFENLNGDRSDENISTYLIDGGLWTACRASRLVMERRFEQSKRKPYEDTYPRYDRTDEVFEKATTGCFDGTPLHPVTVFPHRDLFVLQSNDLKNVDWFLLGLDASMASFAEGFSGVMHVALEYDPKWWYETRPESRSLCMSDDVWEIMEGAFEMWPNVRKLWFIDRSLKRKKDAPAFKEEADNGYEINAFYASDRRFLEVNCNSWVIMEKEWEYIKPVEDKSIDGFSSSLDFIEELQSDLDDKSHPTSDNYFEPYCDIGLLGWDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1C5</accession>
    <name>X0C1C5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1C5"/>
    <dbReference type="HOGENOM" id="CLU_2291808_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="101" mass="11397" checksum="2A5ABA3966A9FAF7" modified="2014-05-14" version="1">MTPLEASTVFTEEHVLVENTPLRPVATAQIQGKSQSKRLRGTWKEDGAICLCENSGSFSSCETVTLRLGPLFRNTAVPQRARRMTMVNWRFRRLKAIPYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1Q7</accession>
    <name>X0C1Q7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979457">
        <property type="protein sequence ID" value="EXK76712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1Q7"/>
    <dbReference type="eggNOG" id="ENOG502RIXF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052068_1_0_1"/>
    <dbReference type="OrthoDB" id="5343483at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="207" mass="23258" checksum="7A4A51F6FE6B4DF3" modified="2014-05-14" version="1">MEHFQSTTSNPLAATGAAVSCWPVKSSSHRQHITPKRHPVPGSSNSPPERLSQRRLRDLTPDLWFEDPYLVCILLSLAQLQWQRRKTTPEAFFVRLLVTNASDTTHAHVFQADIPSKLLHALDNPTEDKDNLVWPAIQHFQVPFDPHASFSERIAGQLLAGLKTRAEEEMPRGEKRKRDEMDTEEQTQSVKAWDGAVQVAGVPLANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2J1</accession>
    <name>X0C2J1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2J1"/>
    <dbReference type="eggNOG" id="KOG0295">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045005_0_0_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="334" mass="36448" checksum="9B31FBC05356F177" modified="2014-05-14" version="1">MGQSSASPSSSPSRSQTSGARDPTSLMDITRRFSRSCSKAEIASVGISPSTSAVFAIYTAAQTSQSWIDVFDIKTQSGYSKTSGSRAVFSPNGSKLATIRDWTVQFTGGFDFHHSSTVFLRDYVSGKTACELKEAKGEPIAWSRDGRLIAVGEARNRIGVWDVKNGVRVGKVLSHIDAVTHAAFLPDQSLVTISRDGTLRITNTKTCKTIRRLEIDGSNNPRALAVSPDGRRIVSVWGTNVHIWIPSANDLTSYNLNAVRAVEGWPLAISPDCRYMLCRTEDGFDIMDVATGTIMYDEATEEMVMSGAFDEDAKVLVLGRMDGVVEVRDVFDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3Q1</accession>
    <name>X0C3Q1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3Q1"/>
    <dbReference type="HOGENOM" id="CLU_1421463_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="191" mass="21703" checksum="DE6D7CB99B8C7A71" modified="2014-05-14" version="1">MTRWWRCSHQTDRDHGCLITQDISSTCVLEFVDYDGRLSWWSVEKCHHLIRSPGLTIAKHKPIEPCRAEGKCSKIGNNSFTIQFEFRNQEMKHPAQRMRTVRQPLKAKVGEAHRILGPSFNTCKLKLKDTTAMELATSLKIEGVQDSGMVTVCGRDSAWRSETVEALADGGNVMPVPRQMWTGPFDTLKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C460</accession>
    <name>X0C460_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979384">
        <property type="protein sequence ID" value="EXK77552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C460"/>
    <dbReference type="eggNOG" id="ENOG502R8UP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035152_0_0_1"/>
    <dbReference type="OrthoDB" id="4990789at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939091" evidence="1">
        <location>
            <begin position="21"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="522" mass="58570" checksum="6F67FDADA760B40A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4A0</accession>
    <name>X0C4A0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4A0"/>
    <dbReference type="eggNOG" id="ENOG502SRIZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036928_0_0_1"/>
    <dbReference type="OrthoDB" id="3644718at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="485" mass="55852" checksum="7AF085ECBFD57DAA" modified="2014-05-14" version="1">MAQDECHLLRLSTELILQILEYGPTSTYLDVALTCTTLHHQCRNLLDLHREAHAKYRITSDLSPETVIDLLKDTTKARIERWHVRELEIWGSRQDWEDWRPWVPKLPGTCGLADGFPTRYGLDLQDMQRYIRTALELWNFSDFDPEVIQWDLKAGQDGFLKLLLIATCPRLHSLRFVKRGLDPHTTLQWMREVIKDSRRTEDGPHELQGFESLRDIAVGIETDQRSWKDISPRRDARDFAALFYVPNLESLSFNDLHYIEDGNEDYQHFDVVDQYDFPRGTSSVKHLSIDSASEFYPEYYQGRADVSKKLESVVLRVASEQRQDLADVGSLSFSNGKTLQKLIIYNPGGMHGYQCRNYRLDDLDDFGNLKLFTLAVSDIELEELHLMHSSPNAEQLILQESVAAGLKTGVHVCTLMNRDDGGYWKNFPGKPDRFELKTGPCYGERPASWRLNLQSGEWGPDCEGCGECKDCLVVYPAELWKSSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4L9</accession>
    <name>X0C4L9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan synthase beta chain-like PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10179</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4L9"/>
    <dbReference type="eggNOG" id="KOG1251">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_4_2_1"/>
    <dbReference type="OrthoDB" id="7773036at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF6">
        <property type="entry name" value="L-THREONINE DEHYDRATASE CATABOLIC TDCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="4">
        <location>
            <begin position="18"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK86133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="319" mass="33327" checksum="02CDF14A942ADDA2" modified="2014-05-14" version="1">MPTFQEIAAASVQSRSRIRHHIYQTPLIPAKKIGRDLKANVLFKAENFQLTGSFKVRGAMSKLSAQGQGRLITASSGNHGIGCALASQTLSKDLTVVLPEIVIPAKLNAIKSYGVDVILHGAEAGVSEQHAQKLAASGDYTYVSPYNDPDIIAGQGTIGLELLEQCDHIDNIFISLGGGGLVSGIGSVLKANNPRIKVYGVSAINSKSLAASMAAGHVVETEHLPTLAEAVAGGIDENTITLGLANAVVDELIDCNEDDIKEALKELAWSESMIVEGSAALALAGFNKVASKLAGQTSVILLCGSNYDQSAISKIISQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C529</accession>
    <name>X0C529_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">INO80 complex subunit B-like conserved region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C529"/>
    <dbReference type="eggNOG" id="ENOG502S7M7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2021186at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029523">
        <property type="entry name" value="INO80B/Ies2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006880">
        <property type="entry name" value="INO80B_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561:SF12">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04795">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01406">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INO80 complex subunit B-like conserved region" evidence="2">
        <location>
            <begin position="295"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="399" mass="43775" checksum="2C8087967F6F0287" modified="2014-05-14" version="1">MGSRPRRSAATKANEVISVHARWADSPERSERSMSSRRSGRASGVSVSRDDASSPGGDRHLSLTVKLPSNKLRQATRGERGFEGGEIVSGKRNRGAKKSYVVDSSPDEDEEEEEEAEIEVEEDDDDEMDVDAEGEEDAEGDIDMDLAPPTITVSKPARSKPAPRASAAKVIQDDDDDDELSDPADSDAGDETMGFGDETMADDGDEDAEGEEIEVAGQEGDEDDDEEEDEEEDDEGDGGDDDDDDDDDEDGNPDESVDLTKMTKRQRARFEDDNAHQYMKLSDEVQAKKVFTAEELSMRRQEMARRRRNLSEKRNEEVKMETINKLLKKQAPKINRKAAAAGAGGSEDSNKPDPVFVRWVSNKNGVRVAVTEEMLDSPAGQVFKPASKLAPGKMVQEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5H0</accession>
    <name>X0C5H0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5H0"/>
    <dbReference type="HOGENOM" id="CLU_1669440_0_0_1"/>
    <dbReference type="OrthoDB" id="4966095at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="157" mass="17705" checksum="8A7B7CFFD6738550" modified="2014-05-14" version="1">MSSTSNTSSATEYWVAAGDVEVDKKENLNPRRATEANYRLPKREALPENTYESLLAALREALEQAFDYPGSRAPFIPAYKSRDDAVSRAKLLRDHGRDSSKIILVDPRRPELAYYRSLQNYAGIVSYHGPALSSSTSAVYLIWEPLTTDHKKREEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5T9</accession>
    <name>X0C5T9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09832</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5T9"/>
    <dbReference type="HOGENOM" id="CLU_072837_0_0_1"/>
    <dbReference type="OrthoDB" id="2537459at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937395" description="WSC domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="34"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK86563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="330" mass="36328" checksum="AFAE433CE36339BA" modified="2014-05-14" version="1">MVHFIKTAFLFISALSLTEAFLNDQGNRPPRAGKRTHRGCYRGLSDTVDPVVKVKGDKSKNTWTACGQYCLTKGKPMALVQGADCYCSESIPNQRKDVGGFGHYCMDPCPGKPTDLVACGSERFGSYSAINTGLKSELWPDQDPLPDDQIPDCLGCTFRLPSDAVLPGRASGVESCRRTCRHLKSKILMMYDKQCVCTNATVSEHALDRVPEEMCSFRWAKKPCGGYSYSLRSALFSVYDASEPQKPAPDVTTPQDAPSPADAQPTRAAAKSSGSSFREIIEDFETETQLQLLIFEGGVWKAFAWIGRVMTKLVTPSEGHEDDDRELDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5U7</accession>
    <name>X0C5U7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_09842</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5U7"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF53">
        <property type="entry name" value="ALPHA-GLUCOSIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="486"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="61"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK86573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="571" mass="62887" checksum="D3636B6A9DD7FE83" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0C702</accession>
    <name>X0C702_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_09864</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C702"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_7_2_1"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04205">
        <property type="entry name" value="CuRO_2_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13910">
        <property type="entry name" value="CuRO_3_MCO_like_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF414">
        <property type="entry name" value="ADR239WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="98"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="222"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="492"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK86594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="617" mass="68238" checksum="FCDDC83DF17D4073" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB32</accession>
    <name>X0CB32_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-xylosidase C-terminal Concanavalin A-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658455">
        <property type="protein sequence ID" value="EXK79882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB32"/>
    <dbReference type="eggNOG" id="ENOG502S8JK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077442_2_0_1"/>
    <dbReference type="OrthoDB" id="42525at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009784">
        <property type="entry name" value="DUF1349"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332:SF2">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07081">
        <property type="entry name" value="DUF1349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="23332" checksum="341E38F628B80F1C" modified="2014-05-14" version="1">MKFTLFSGVPSQPPLPENPLSEPFELVALPGPDIWRTPSCAGGRDDFSGPIYATPIPLNSFKSAKVTISSDFPGNYSQGGLILFMPESIPMTQTDSQLRLEESPRTWIKAGIEKVDGEFFASVAAAKPYSDWSLVKLSESSATFEMEKAKGSLWIYVTGQDGKRTPVRKLTWVVDVAPANDIWIGVAACMPKGDESQSGGMLKVQFRDFSVSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBN0</accession>
    <name>X0CBN0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Surfeit locus protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_08592</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBN0"/>
    <dbReference type="eggNOG" id="KOG3998">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056195_0_0_1"/>
    <dbReference type="OrthoDB" id="7859621at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002995">
        <property type="entry name" value="Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF1">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02077">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01339">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK88224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33817" checksum="D6ADCA92B3B763B3" modified="2014-05-14" version="1">MSQRFNSGYGLGGPAPYGGSQAADPQQGEGFLEQIRPYTSKIEDALDTISEPIKPYLPAIGRFLIVVTFFEDALRIVTQWSDQLLYLKDYRHIPSGITHLFLLVNIIAMFSCSTLVIIRKHSDYAVAGLMGVVVTQALGYGLIFDLNFFLRNLSVIGGLVMVLSDSWVRKTQVFAGLPQIDEKDRKMYFQLAGRVLLIFLFIGFVFSGEWSLWRVIVSSLGGISCVMVVVGFKAKYSATLLVVILSIFNLLVNNFWTLHEHHPHKDFAKYDFFQILSIVGGLLLLVNSGPGQFSIDEKKKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCG4</accession>
    <name>X0CCG4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Minor extracellular protease vpr</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_08339</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCG4"/>
    <dbReference type="eggNOG" id="KOG4266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003559_3_1_1"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02124">
        <property type="entry name" value="PA_PoS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 9 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936313" description="Minor extracellular protease vpr" evidence="11">
        <location>
            <begin position="18"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="12">
        <location>
            <begin position="156"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="13">
        <location>
            <begin position="382"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="14">
        <location>
            <begin position="615"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK88529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="882" mass="94332" checksum="B9BBF6567FB66209" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCW3</accession>
    <name>X0CCW3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_06129</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCW3"/>
    <dbReference type="eggNOG" id="KOG3411">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108559_0_0_1"/>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000118">
        <property type="entry name" value="40S ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001266">
        <property type="entry name" value="Ribosomal_eS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01090">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01413">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="115"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK92250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="150" mass="16612" checksum="18B5D29C0F7D1C7B" modified="2014-05-14" version="1">MAGGVTVRDVDAQKFITAYSAFLKRQGKLPIPGWVDTVKTGPAKELPPQDIDWFYVRAASIARHVYLRKTVGVGRLRKVHGTAKNRGSRPSKHVDASGSVDRKVMQALEKIGVLEQDEDKGGRRITQAGQRDLDRIAQTTAEAEEEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD01</accession>
    <name>X0CD01_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_14976</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KI979337">
        <property type="protein sequence ID" value="EXK80542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD01"/>
    <dbReference type="ESTHER" id="fusof-f9fiu4">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_6_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152152" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="25"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="32"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK80542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="578" mass="63179" checksum="CBF289828B0B9C7A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDR4</accession>
    <name>X0CDR4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658436">
        <property type="protein sequence ID" value="EXK80762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDR4"/>
    <dbReference type="eggNOG" id="ENOG502RX75">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008809_0_1_1"/>
    <dbReference type="OrthoDB" id="5340195at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF3">
        <property type="entry name" value="FORMYLMETHIONINE DEFORMYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="606"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="639"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="649" mass="72789" checksum="ED1955CAF2037CC8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFG1</accession>
    <name>X0CFG1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFG1"/>
    <dbReference type="eggNOG" id="ENOG502RJDF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055482_0_0_1"/>
    <dbReference type="OrthoDB" id="5293596at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="220" mass="24710" checksum="DAC7DF8067AC6221" modified="2014-05-14" version="1">MGGLEGWLIRRMSLPKHMGSLRKQFYFTLFYTITAVFAFANSTIYFFITRQHKSDDASGEPQPEPQPPNGTASHVWAPYAEKTPAAPFTDIFGEGWFRAFIILSLYAFGSSVMVFEILVLNSIRRPWTVGIHLIGIMFFATAYLGWAAFGHLVTNYYPFFWLDKNEVGSDEAITLYSIGFVFLIPIMYILMQGLIASRESVTRSNSEARAIAAAQAALDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGU3</accession>
    <name>X0CGU3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGU3"/>
    <dbReference type="HOGENOM" id="CLU_1299787_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="212" mass="24072" checksum="7702AE43A31F4764" modified="2014-05-14" version="1">MAVAASVPSRPALRVGILAALGIFFFVILFTFYSDTVRSPVEFAHRKAQQYCDSSQTTIPSFTPTPTPVSTVAPEPTPEPIRNCEDPYRRPGYLYIPKEPKAYRDTQWIPFTEDYLNSEPPEYAAYPPKHEIVFNDTAVEPEYLNAAGNPQQWMRMAVVESRRRRKAVEATVPPTRNKTVNDFVNMKDDNGLGWLWGRRVVMLLFILRSSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHI5</accession>
    <name>X0CHI5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13583</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHI5"/>
    <dbReference type="HOGENOM" id="CLU_3242171_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="43" mass="4940" checksum="2B37B8D8EDB07087" modified="2014-05-14" version="1">MKARDNYRKHYAMIRQVTGVLVEDHAYKAVQDCCLGCQGTIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHY4</accession>
    <name>X0CHY4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_04985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHY4"/>
    <dbReference type="eggNOG" id="ENOG502RNM7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029372_0_0_1"/>
    <dbReference type="OrthoDB" id="4161727at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="315"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="204"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="469"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK93781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="564" mass="63791" checksum="666FD503B98AEEC4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJI9</accession>
    <name>X0CJI9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_04451</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJI9"/>
    <dbReference type="eggNOG" id="KOG1632">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029385_0_0_1"/>
    <dbReference type="OrthoDB" id="436852at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037869">
        <property type="entry name" value="Spp1/CFP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174:SF1">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="119"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK94346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="442" mass="48838" checksum="8742DE28E57859BF" modified="2014-05-14" version="1">MEQTIPTIGQSEDSRSEPVENDTKSETVAGSTPQPPADAHPASSNSPSHPPSTSAELYNMAAHTASKKKGTASAVKKTPKRSKKTGGPRAAKRAKPARSGSTGDAHESAGSELEESDHGPYCLCRGADDHRWMICCENCEDWFHGECINMNKEIGENLIEKFICPLCTNENLTTLYKKTCALGGCKKAARIAQEEKSVFCSNEHAQTWWERMVAKLPKAKGKGGVNDQLTQEEFMALLQGGLSGTDEEGLWRLVKAPFAGTESNGTNGTEKENPDQMHLSAEEKEYLENAAAARFHLAEETVLCHKMLTLLEFAHERRQAAITAGRFKEDICGYDQRLDSISARDAFEAFAKSPEGEAIFKASQLSDPLGEGDEVRGMCERKRCKIHSGWYKMLSLGLKHQIREMATQADEVGEEEKAMRQAAKDRWRRKQSEKNWVEVLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLQ5</accession>
    <name>X0CLQ5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLQ5"/>
    <dbReference type="HOGENOM" id="CLU_1061889_0_0_1"/>
    <dbReference type="OrthoDB" id="5070447at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="257" mass="27570" checksum="42780FC425B4C6AD" modified="2014-05-14" version="1">MPDFRPLFFIAKVLTCCCCCSRRKPENARAADRPYGTSHDQRTGSSSENVSDYSEYSVPPAYPGGPVNLIHPDEFEHPDELDEVHGRDEFSFDLQKSRSLVPCPPTPRPSSPVDSEPGTTRPSTAKSTTTKTISDEPVASPSVIVEITATDSVTEMLLANEPSVTKLAGPVPIRDDPTATKSVATEPEPESEPAEAGPTETKTDRPNFVNVDLVEAGPLKSDIEASEVNNGTTEASSDAVGPTENKDEDKGKKKVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM99</accession>
    <name>X0CM99_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL4m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_04123</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CM99"/>
    <dbReference type="eggNOG" id="KOG1624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041575_4_0_1"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000016">
        <property type="entry name" value="60S ribosomal protein L4, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF6">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK95565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="320" mass="35330" checksum="F6FF0307355D0BB1" modified="2014-05-14" version="1">MAGKGIGCLAEAMGALRVSAKPATLNKAFTRSMATEVSPKQTAENKSPNTPQGILESWKPITTVPVTVHAFPSLEPTSLERWDVNHLYLPLRRDLLHLAVVYEGDNTRQGTASSKTRYDVHGSHRKMRPQKGTGRARMGTKQSPVNRGGGKTFGPHPRDFGTSLTRKVYDKAWRTALSYRYRKGDLIVCEDGMDLVLPTDYELVAGKYLKDGLKEAYLKRYMTGVLGNLGLGRASGRTLFVTGNRREALFGAMEQLPWEGRALDLEDVDVKDLLETGKVVLERSVLKEMIKKHQSDLVSRVVMQGLVKGGPKLGTPVIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CND4</accession>
    <name>X0CND4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CND4"/>
    <dbReference type="HOGENOM" id="CLU_2454442_0_0_1"/>
    <dbReference type="OrthoDB" id="4410170at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937137" evidence="1">
        <location>
            <begin position="19"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="89" mass="9857" checksum="8FE71283448D35AC" modified="2014-05-14" version="1">MQISALITLFSLATGTNAWAQAGNGEWIANNKIYDVTNSGFAKATMEACTYRNTETRVPIGQPCKYWLDGNGRIASGVCREDQYMYYCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNI9</accession>
    <name>X0CNI9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNI9"/>
    <dbReference type="eggNOG" id="ENOG502SW7I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117724_1_0_1"/>
    <dbReference type="OrthoDB" id="5372011at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="139" mass="15836" checksum="72179DE7239E076A" modified="2014-05-14" version="1">MSSSTQHHQPNRSSGWTEEMRDRQARGKNPYSEESDVSDGEPRRLGPRYRSSASRSFSADADSYSPVFETHVERERRGEAMYILDNHAALMAHAQATGDSIAGQRLRFMRQLCGFEDKHDDTSTARSKQSRRVSDKISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPB7</accession>
    <name>X0CPB7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPB7"/>
    <dbReference type="HOGENOM" id="CLU_3242184_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="43" mass="4780" checksum="908B62DEBAB0EFD3" modified="2014-05-14" version="1">MQDLCVLRAFLPVVRLLLRGPSPVRPCGRAPCFLPVVRYLVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPG6</accession>
    <name>X0CPG6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPG6"/>
    <dbReference type="HOGENOM" id="CLU_1749720_0_0_1"/>
    <dbReference type="OrthoDB" id="10370626at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="155" mass="16464" checksum="57C2428DD97CF322" modified="2014-05-14" version="1">MAPKKTTVKSGPAGVAKRNVPSETQSRSASNSSTKSAASSVATPTLTTPAGVKKPSRNDTGTADHATKMVQWHKARASQRQAEKRALEAQIGQLERWIADDVDKAAGWQMTADELAKKEAGSSVEGPFAAALEKKKAEEAKPSDEKTELESKEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ68</accession>
    <name>X0CQ68_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_04757</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ68"/>
    <dbReference type="HOGENOM" id="CLU_033323_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045820">
        <property type="term" value="P:negative regulation of glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043456">
        <property type="term" value="P:regulation of pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051695">
        <property type="entry name" value="Phosphoglycerate_Mutase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517:SF1">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK93473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="27762" checksum="4DF4E01E5C170D5C" modified="2014-05-14" version="1">MRLFLIRHGETVDNVANLYAGSRDSALTAHGVMQAQRLASHLSEHVAIDRIFSSNLSRAVHTAQAILDAQKRAKDLKLIQVPELREKDFGTGEGTKFGAATKHEGSETPQAMRERADVFLDEHLPRLHEDSTVCIVAHGIILGTFYKALRDRTSSSAGPDAELEGRASAFVRPSWSNTGYIEALITRDSSDKHLQMRVVKINSVDHLKGLRKTRGGIGSAKFDAKQKTMDSFFKPTSRKRKLEDEDIVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQM9</accession>
    <name>X0CQM9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQM9"/>
    <dbReference type="HOGENOM" id="CLU_2171136_0_0_1"/>
    <dbReference type="OrthoDB" id="4967971at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="110" mass="13065" checksum="1DDE4F3F04698AFB" modified="2014-05-14" version="1">MTILPMKKTAVLERSRRVSIWDNPPTQSDALNWWIGETVRLGRATDEFWDDLKNPASAIEKTRTAHNLEARGTEQRLINESWEHFVWYFLEEAKRIELHDWAYANGFYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQY4</accession>
    <name>X0CQY4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_02264</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQY4"/>
    <dbReference type="eggNOG" id="KOG0707">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6334211at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:GMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000776">
        <property type="entry name" value="Guanylate kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117:SF13">
        <property type="entry name" value="GUANYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117">
        <property type="entry name" value="GUANYLATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="9">
        <location>
            <begin position="38"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK96855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="224" mass="25296" checksum="A8ECCDF167ADA59E" modified="2014-05-14" version="1">MRWFLGYAKRNSNLLIPSTKPFSQVPKRSFAMASPSDRRPLVISGPSGVGKGTLIKMLFSRHPDIFTLSVSHTTRNPREGETDGVEYHFVTKDAFRDLIAKDGFVEHAQFGSNLYGTSKATIEEQTAKGKVVVLDIEMEGVKQVKASSIDARYVFISPPDTEELEKRLRGRGTETEESIQQRLTRAQDELAWAKNAEFDKILVNDDLEKTYQELDAFVYSEKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRW0</accession>
    <name>X0CRW0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ThuA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRW0"/>
    <dbReference type="eggNOG" id="ENOG502RZ2Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057383_1_2_1"/>
    <dbReference type="OrthoDB" id="3482285at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40469:SF2">
        <property type="entry name" value="GALACTOSE-BINDING DOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40469">
        <property type="entry name" value="SECRETED GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThuA-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="242" mass="26603" checksum="FC3C02FF521A3BBD" modified="2014-05-14" version="1">MASTAPGSIKVLLLTKTCGYRHDCIPTLISAFNSLPFSVSATEDSRELLSLSDYDVVALGHNTGDYLNEEEVTSLLNFVENGGGVVGIHAATSGLKTNARYTKILGEVFNGHPPPQWMTLAVETPEHFINGYESLPGPDSAPEEAHACPVKTESLPASQFPWFDEVYTFRSHPRIEGRTILLSVRGDNEESAESAGFPLSWTQTVGKGRVYYTALGHFDEAYKNAWFMESLRRAVVWTAKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTB8</accession>
    <name>X0CTB8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">General transcription factor IIA subunit 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Transcription initiation factor IIA small chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_04304</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">TFIIA is a heterodimer composed of the large TOA1 and the small TOA2 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIA subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTB8"/>
    <dbReference type="OrthoDB" id="586585at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10014">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10145">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.190:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.18.10:FF:000003">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.190">
        <property type="entry name" value="Transcription factor IIA gamma subunit, alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009083">
        <property type="entry name" value="TFIIA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003194">
        <property type="entry name" value="TFIIA_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015871">
        <property type="entry name" value="TFIIA_gsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015872">
        <property type="entry name" value="TFIIA_gsu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10966">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02751">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02268">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit N-terminal" evidence="11">
        <location>
            <begin position="26"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit C-terminal" evidence="12">
        <location>
            <begin position="77"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00063181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK94124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="127" mass="14019" checksum="AE1ED65D385DA659" modified="2014-05-14" version="1">MSCTVEAGTAPYCYALLCDSLTNMVHCSIGLALTDTLDDLISDERINPQLAMKILSNFDQAITEALQKNVKARLQFKGSLDTYRFCDEVWTFLIKNVTFKMDNGSQSVTANKVKIVSCNAKKPGEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTF0</accession>
    <name>X0CTF0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02798</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the exportin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2215036at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042565">
        <property type="term" value="C:RNA nuclear export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045478">
        <property type="entry name" value="Exportin-5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF3">
        <property type="entry name" value="EXPORTIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19273">
        <property type="entry name" value="Exportin-5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="3">
        <location>
            <begin position="43"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1235"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1252"/>
            <end position="1272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK97695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1293" mass="146045" checksum="D4084DBA5F6D59A5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTW2</accession>
    <name>X0CTW2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Non-structural maintenance of chromosomes element 1 homolog</fullName>
            <ecNumber evidence="4 15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_04427</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the Smc5-Smc6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the NSE1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4 15"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTW2"/>
    <dbReference type="eggNOG" id="KOG4718">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045153_0_0_1"/>
    <dbReference type="OrthoDB" id="185455at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16493">
        <property type="entry name" value="RING-CH-C4HC3_NSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011513">
        <property type="entry name" value="Nse1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014857">
        <property type="entry name" value="Nse1_RING_C4HC3-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973">
        <property type="entry name" value="NON-SMC ELEMENT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07574">
        <property type="entry name" value="SMC_Nse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08746">
        <property type="entry name" value="zf-RING-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="13 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Non-structural maintenance of chromosomes element 1 RING C4HC3-type" evidence="17">
        <location>
            <begin position="230"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="294"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="319"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU368018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK94304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="331" mass="37991" checksum="EEA4D978F8FB59A6" modified="2014-05-14" version="1">MSSHEFNHGDRAFLQAILARGTITFEEARPILAAIFNANRRHSGDEEGDEVRTDQITEEHFQEAIDKASEAASLFDYEIRSTFHQITKKRIWALVNTTSDPQTQLATTYSHEEISFIKRVLDAMFEKFNTPRMEVMAITEMQAIKLARPNRRESQIDVETQTQTTVDKGLKHSEVEAVLANLVEGGWFEKSNEGFYTLSPRALLELRPWLVESYNDPDLGLRDWQRIKFCEACKDPVTIGLRCAEVDCNFRLHEVCEEAFWRTRRDSKCPRCSTEWSSHKFTGERAVTSTDAFQRGRRKNGSGWQRSTLADEVIRDEGGADEVEDEDVDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUF9</accession>
    <name>X0CUF9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUF9"/>
    <dbReference type="HOGENOM" id="CLU_2941853_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="60" mass="6611" checksum="06EC717932EFDDD9" modified="2014-05-14" version="1">MPFYPELAASFIGELTKYIQCQSTLEALKNPPETYTSSPTDILGGLKKNSQYQLLKSVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUH8</accession>
    <name>X0CUH8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUH8"/>
    <dbReference type="HOGENOM" id="CLU_3279521_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="41" mass="4883" checksum="4BB5BB78A56C74E9" modified="2014-05-14" version="1">MVSLKVQNCFPVTAFLPRGLRVYNWKVNQGENRQEDNHVYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVH2</accession>
    <name>X0CVH2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Translation initiation factor 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_03657</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVH2"/>
    <dbReference type="eggNOG" id="KOG2767">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026663_1_0_1"/>
    <dbReference type="OrthoDB" id="10250831at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071074">
        <property type="term" value="F:eukaryotic initiation factor eIF2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11561">
        <property type="entry name" value="W2_eIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000031">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.350:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="7">
        <location>
            <begin position="256"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="163"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK94864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="423" mass="46888" checksum="A598BCB1CB3D42AD" modified="2014-05-14" version="1">MALVNVRRDVSDAFYRYKMERLQTKIEGKGNGIKTVVVNLSSVAASLARPGSYVIKYFGFELGAQTNIDPKDDRWIINGAHDAPKLQDHLDGFINKFVLCKKCKNPETDVVIKDDRILLDCKACGQRTDVDIRLKLSGFILKNQPKKGKKDKAERRAAKKARQNGNAANGTNGQNGAGSDEASENGSNDNGDEDVGSDDEFQKVAAEAAEAAQENEVKEHEWAVDMSEEAVKARQASLPGEFKQKLNIGDDDDEEGEGGPTIYDELGDWIQSQAEEKGSVDKVESIDIYVKAKELGIEGKHRSVLVLVQTIFDKNIVAQIPKRASMLKQFVTSERHEKALLGGTERLVGTLAADHPEMFQSIVKILQLYYHYDLISEEVVTKWGSKASKKYTDISTSKKVRKAAEPFLTWLAEADSEESSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVL2</accession>
    <name>X0CVL2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVL2"/>
    <dbReference type="HOGENOM" id="CLU_1102826_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="253" mass="27966" checksum="B8FCA8F901065849" modified="2014-05-14" version="1">MAATLVLRSTMALVWVVASILRHMHGLVILALVVSLEWHLRLPLIHGGRMWRGGIRNLGWSWACVPMVRGAWIQLNRFMELGKRILGHVHVCKATRSGNGSHRLRRHRHVTHGWHRGRVLGDHVRVGHGRLVHGLLRSNDRLTLGGLLRSNDELALRSSLRGIALARLTTLVTRLVGFTRDRSAAHVLLRCIGSLELGLVQEVALQVLLGQMATSDKASLGLLLPRPLLVWRASALAPGAVVALREVNGRRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVL4</accession>
    <name>X0CVL4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1941 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVL4"/>
    <dbReference type="eggNOG" id="ENOG502S540">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028752_0_0_1"/>
    <dbReference type="OrthoDB" id="8962942at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008709">
        <property type="entry name" value="Neurochondrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109:SF7">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05536">
        <property type="entry name" value="Neurochondrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="628" mass="69719" checksum="505341043EE11EFB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVM8</accession>
    <name>X0CVM8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVM8"/>
    <dbReference type="HOGENOM" id="CLU_2483451_0_0_1"/>
    <dbReference type="OrthoDB" id="4991178at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="87" mass="9812" checksum="FB1436DD9E449BC5" modified="2014-05-14" version="1">MSPLPSNLTLRNTPPGYRLQAQSVAESDYYPSDEYGRADDTARLDWWSNPADATERIAVFAIVTGILCVIIIVLFLRIRKLRMGPIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXX5</accession>
    <name>X0CXX5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rpr2-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_01711</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the eukaryotic/archaeal RNase P protein component 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXX5"/>
    <dbReference type="eggNOG" id="ENOG502SCED">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079140_1_1_1"/>
    <dbReference type="OrthoDB" id="128536at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK99026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="21100" checksum="4AC941C2178F9520" modified="2014-05-14" version="1">MAKGKEPKGVQNRIIYSRASYLYQAASYLTKQSSTGQDAAAKSSTPSHGHSVSPQTRNEERALRNMSRQAISDLRAVTLKAQIRRSPAMKQTICKFCDTLLVEGDTCTSTVENASKGGRKPWADILNINCNTCGNVKRYPVCAPRQKRKHMRKLDHKEGTEYSSNESKVQGPTAQTTPHETPIPTPGQTPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXX9</accession>
    <name>X0CXX9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01714</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXX9"/>
    <dbReference type="HOGENOM" id="CLU_021479_0_0_1"/>
    <dbReference type="OrthoDB" id="5302359at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000424">
        <property type="entry name" value="Meiotically up-regulated gene 72 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF25">
        <property type="entry name" value="PROTEIN PAM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="3">
        <location>
            <begin position="200"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="568"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="662"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="735"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="749"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK99031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="768" mass="83239" checksum="68E29993EBFF09DF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYQ7</accession>
    <name>X0CYQ7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYQ7"/>
    <dbReference type="HOGENOM" id="CLU_2184112_0_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937510" evidence="1">
        <location>
            <begin position="18"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="109" mass="12368" checksum="5106987248EBACFD" modified="2014-05-14" version="1">MNSLLVLALWAAGSCIAFSIANSYWSHLRYDAKRNPQGCQRAPRMPNKYPFAVDFFLAAIKADKEKKFPETIVKRYGKVRHAGAFEHYTLGNHDVSINDPRNVQTVLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0S7</accession>
    <name>X0D0S7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent DNA ligase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00587</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0S7"/>
    <dbReference type="eggNOG" id="KOG0967">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004299_4_0_1"/>
    <dbReference type="OrthoDB" id="2160351at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08039">
        <property type="entry name" value="Adenylation_DNA_ligase_Fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF2">
        <property type="entry name" value="ATP DEPENDENT DNA LIGASE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02430)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="7">
        <location>
            <begin position="384"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="679"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="679"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="734"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL00391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1011" mass="113597" checksum="30B0172CCE9D3245" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D121</accession>
    <name>X0D121_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_00416</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D121"/>
    <dbReference type="eggNOG" id="ENOG502RVVC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4682787at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="34"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="370"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXL00112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="412" mass="45571" checksum="F55428ACF84787A9" modified="2014-05-14" version="1">MATNKDIDLHEENGSVLVATAITLLTLSWFSVGLRTYTRAVLMKSLQLDDWLMLVAQIIFTISCAFILEGVQQGIGKHNDAIKPDEAKVQALMWQALATATYILDMMFIKLSIGVFLLRLCVKRVYVWIIWISLAIISIWSIVLFFWNLFQCKPVEMHWDFRIKDGTCVSADQIVSAAYAISVMTVVSDWLYALLPIPMLWSVKMTKQAKATVIAILGLGIFASVATLVRLRFLADLTDTEDILFAGTDAMVWTLIEPGVAIVASSLATIRPLLRAMRIRGFESTENTYGTGHSAAVRSNANRSKPGILIMPGFGPDDVSLTNMVSQNNTNSLSHPNDIEILPPRHVADGPISPGQASIVKSEILVIQGNSSPPSSWQSRNDRSASSSFDQIHDLEAYSQELERDNIRGRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0D126</accession>
    <name>X0D126_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glutamate 5-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_00651</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D126"/>
    <dbReference type="eggNOG" id="KOG1154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025400_1_1_1"/>
    <dbReference type="OrthoDB" id="409889at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21157">
        <property type="entry name" value="PUA_G5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.10:FF:000008">
        <property type="entry name" value="Glutamate 5-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000020">
        <property type="entry name" value="Glutamate 5-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF3">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="10">
        <location>
            <begin position="330"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXL00491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="454" mass="49524" checksum="A7228C509EBD3FFB" modified="2014-05-14" version="1">MRKMTSESMFQFMRGNGTKSLTIVIKLGTSSIVDEKTHEPLLPILTLIVDTAVKLRKDGHRVVIVSSGAIGVGLRRMDVEKRPKHLAQLQALAAIGQCRLMSLWDSLFTHLRQPIAQILLTRNDIADRTRYFNAQNTFHALLEQGVIPIVNENDTLAVSEIKFGDNDTLSAITAAMIHADMLFLMTDVDCLYDKNPRTNPDAKPIEVVEDIAALQADVSSAGSSLGTGGMSTKIIAARLGTSAGVTTVITRSSNPGNVLNIVQYLQSIQRGNTPPSPDERAEGLSRSASALTLSNLNGAPWPPLHTRFIPANDPIRDRHFWLLHTPHPHGTLYIDSGAYKALVGKAGLLPVGVIDVEGNFAQQEVVRLVAVKRRSTPGPDGKMWEGTPEEVGRALVNYAAAEIARIKGKQSVEIEKILGYADSEYVAHRQHVGFFKRDSRPVSPAREINGAVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1X8</accession>
    <name>X0D1X8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_00773</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PRA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1X8"/>
    <dbReference type="eggNOG" id="KOG3142">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103851_1_1_1"/>
    <dbReference type="OrthoDB" id="63113at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004895">
        <property type="entry name" value="Prenylated_rab_accept_PRA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317:SF0">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03208">
        <property type="entry name" value="PRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXL00756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="176" mass="19478" checksum="FD4F5E00B981EDFA" modified="2014-05-14" version="1">MSRIQIPLDVITSRLNFGDRFQGLRSGPLSGRFSNLRPVGEFLDFKRLSKPANFVEMQSRVNYNLSHYSSNYAVIFVMLSIYALLTNWLLLFDIILVVVGMWFIGKLDGHDLEIGTFRASCSQLYTALVCVAVPLGLIASPFTTLLWLIGASGVTILGHAAFLDKPIDEAFSGEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2U4</accession>
    <name>X0D2U4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial glycine transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Solute carrier family 25 member 38 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_07778</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>glycine(in) = glycine(out)</text>
            <dbReference type="Rhea" id="RHEA:70715"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK88997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2U4"/>
    <dbReference type="HOGENOM" id="CLU_015166_0_3_1"/>
    <dbReference type="OrthoDB" id="1924968at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015187">
        <property type="term" value="F:glycine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904983">
        <property type="term" value="P:glycine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03064">
        <property type="entry name" value="SLC25A38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030847">
        <property type="entry name" value="Hem25/SLC25A38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181:SF3">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10 12" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="30"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="136"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="242"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK88997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="330" mass="35656" checksum="E892F4E355CAEA34" modified="2014-05-14" version="1">MGISIAGSPTQHNGAAVSLPMTEPRASRSANSARHFISGLGSGVTSAVLLQPLDLLKTRVQQSGSSSLSATLRDLRQSSSLVKSLWRGTVPSALRTGFGSALYFTSLNAIRQHAHQTGILGRRLQTQGRSSVLPSLTNSGNLISGAVARTFAGFVLMPLTVIKVRFESSLYSYPSIMSAANDIRRTHGWRGFFSGFGATAFRDAPYAGMYVLFYEMLKSRLGSLASKPVASGEGPTRMQATLASSVNFTSAMLAGAACSIVSNPFDAVKTRIQLQPLEYRNIWHAWYKMVTHEGIRSLWDGLALRMSRKAMSSALAWTVYEELIRRAGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D349</accession>
    <name>X0D349_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D349"/>
    <dbReference type="eggNOG" id="ENOG502S4U3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_685169_0_0_1"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF6">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="349" mass="38541" checksum="C8062B7E789DF303" modified="2014-05-14" version="1">MTENRQRNVLVTGANGYIGSAVCRAFVRAGWNTYGLIRNPQAREELALSEIIPVVGSFTDLSFLETLFVEVNTFDTIVSCTEKIPGYAAHFGEVMACVKRLAEKSNENGVRPLVLWSSGCKDYGKTGLHGTPGLVPHTEASPLNVPEILKERTTNSAKVFNYTELFDAAVIRPTCVFGYSNSYYGAIFDYAADQREKGSEVLRIPGDPNSIMHATHVDDCGRAYVSLAELDDRRAVGCQFFNVSGYRYETLEEVAGAVAKEYGFDRGVQFVPASEAEPSFPPGLHFVFSFSQWVGSDKLRSLTGWKDKRELFSKGIHAHRLAYEAYKGRGNANVAEIQKRIGGNFNAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D453</accession>
    <name>X0D453_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D453"/>
    <dbReference type="eggNOG" id="ENOG502RIYQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027003_0_0_1"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1000">
        <property type="entry name" value="arf6 gtpase in complex with a specific effector, jip4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK97914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="535" mass="60499" checksum="7E0CC447D48299BC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0D494</accession>
    <name>X0D494_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D494"/>
    <dbReference type="HOGENOM" id="CLU_2527508_0_0_1"/>
    <dbReference type="OrthoDB" id="10281466at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="84" mass="9063" checksum="D2F006678952ABFA" modified="2014-05-14" version="1">MSATAPTTDEGPEPGKWVETKAKLENGYKYCAILACVAGFGAIFWFVILPEFCEANATAATGHYARSHPRHLGFLPPKLGPPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4A0</accession>
    <name>X0D4A0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WW domain-containing oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4A0"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_3_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000253">
        <property type="term" value="F:3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051593">
        <property type="entry name" value="Ergosterol_Biosynth_ERG27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43647">
        <property type="entry name" value="DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43647:SF4">
        <property type="entry name" value="KETOREDUCTASE (KR) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="36156" checksum="EEF96BD111EA959B" modified="2014-05-14" version="1">MTGTIIITGANGSLALAYISHLIKIHPSYTILATVRDASPSDPNTAQLSSLLSSHPKSSIEALDLCLLSNVRGFSENTAKRVATGEIPPIKAIICNAFTMSVSEQVYTPDGFERTFQVNHLSHFVLVLKLIGRMASDGRIVMLGSDTHYTTRSHPLFRQRPGIPEDTELLVKPLPDKKGKEYDGGFHRYGNSKLANIMFMHDLNAKLEKNPKLSSITAIAMDPGGMVDSRAHRIQTPFMRFAFSLVLILLPVLRHFTDTMRSAAQSGRELVELSVGERFKGAKGYFMGARREEEDIACKDVHKRELLWNACWKWAGMKEEETVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4V5</accession>
    <name>X0D4V5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4V5"/>
    <dbReference type="HOGENOM" id="CLU_1906813_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="124" mass="13866" checksum="18EE25DD95009FE2" modified="2014-05-14" version="1">MVDHLNTNGSVFVHSDGELKHYIEVHIINTLFESSGLHLATLTANPSFLFNFHIDASVTDCLMFKAQLVLLVAHLLPLLLLLLLLNGNCDVLPYSVNHFDSLPNFIAGLFFRVPYSKLLSQQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7J4</accession>
    <name>X0D7J4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_00021</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7J4"/>
    <dbReference type="eggNOG" id="ENOG502QW6D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011003_0_1_1"/>
    <dbReference type="OrthoDB" id="4060227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF17">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="592"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK99538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="643" mass="71831" checksum="704FC98AF504C5B0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0DFR9</accession>
    <name>X0DFR9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peroxisomal short-chain alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05459</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DFR9"/>
    <dbReference type="eggNOG" id="KOG1200">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_8_0_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF37">
        <property type="entry name" value="CLAVALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK93332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="32124" checksum="826B1FEAC1D39EC7" modified="2014-05-14" version="1">MLSSGRDTQGPVDGYISTEIHNDTYAAISPSNFDFDGVTVLITGASRGLGLAMAISFAKAGASQIAIGARSDLSASSASIVDAASKAGRKRPRILELNMDVSDPVSVDSAAAKIRSEFGRLDIVVNSAGILAGDGKIVDSDPEGWARNFAINSNGLYLVLRAFIPLLLSCDGKKTIINVSSIGAHCVSPTLSGYQISKLATLRLAEFATAEYGEKGLLVYSIHPGSVATEMVLQQWPQSPELSKAFADKPELAGDSIVYLTSEKRDWLAGRYVNVTWDLPELMEKKEWIVAGDRLKLKISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0DGV9</accession>
    <name>X0DGV9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_04909</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DGV9"/>
    <dbReference type="eggNOG" id="ENOG502SM2K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023111_0_1_1"/>
    <dbReference type="OrthoDB" id="258392at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF127">
        <property type="entry name" value="HISTIDINE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738268" description="Acid phosphatase" evidence="4">
        <location>
            <begin position="19"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="457"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="490"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="531"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK93667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="585" mass="63566" checksum="2DEEFBB409615A5A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0DN59</accession>
    <name>X0DN59_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_03058</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DN59"/>
    <dbReference type="eggNOG" id="KOG2189">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005230_0_2_1"/>
    <dbReference type="OrthoDB" id="10264220at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026028">
        <property type="entry name" value="V-type_ATPase_116kDa_su_euka"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001293">
        <property type="entry name" value="ATP6V0A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="548"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="578"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="642"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="754"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="785"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="279"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK95762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="857" mass="97491" checksum="9C400BBFDBF7F714" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0DNE6</accession>
    <name>X0DNE6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03118</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-galactosyl-(1-&gt;3)-1D-myo-inositol + sucrose = raffinose + myo-inositol</text>
            <dbReference type="Rhea" id="RHEA:20161"/>
            <dbReference type="ChEBI" id="CHEBI:16634"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:17505"/>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
            <dbReference type="EC" id="2.4.1.82"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolases 36 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DNE6"/>
    <dbReference type="eggNOG" id="ENOG502QPVE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047274">
        <property type="term" value="F:galactinol-sucrose galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000222">
        <property type="entry name" value="Raffinose synthase Sip1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008811">
        <property type="entry name" value="Glycosyl_hydrolases_36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268:SF32">
        <property type="entry name" value="GALACTINOL--SUCROSE GALACTOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05691">
        <property type="entry name" value="Raffinose_syn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK95862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="891" mass="99754" checksum="DFD575AEAA7B43CD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0DPT2</accession>
    <name>X0DPT2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DPT2"/>
    <dbReference type="eggNOG" id="ENOG502QQCH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020809_0_0_1"/>
    <dbReference type="OrthoDB" id="10253390at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021829">
        <property type="entry name" value="DUF3419"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473">
        <property type="entry name" value="BTA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11899">
        <property type="entry name" value="DUF3419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="840" mass="94534" checksum="388F9EC413CE72A7" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0DRI0</accession>
    <name>X0DRI0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">alpha-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glucosidase II subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_02288</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; N-glycan metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="5"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DRI0"/>
    <dbReference type="eggNOG" id="KOG1066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_7_0_1"/>
    <dbReference type="OrthoDB" id="3237269at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017177">
        <property type="term" value="C:glucosidase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06603">
        <property type="entry name" value="GH31_GANC_GANAB_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000023">
        <property type="entry name" value="neutral alpha-glucosidase AB isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF54">
        <property type="entry name" value="BCDNA.GH04962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937617" description="alpha-glucosidase" evidence="14">
        <location>
            <begin position="31"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="16">
        <location>
            <begin position="98"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="15">
        <location>
            <begin position="387"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="18">
        <location>
            <begin position="724"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5110" evidence="17">
        <location>
            <begin position="836"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF17137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK96882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="963" mass="109369" checksum="C433CEBE00F494EC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DTR1</accession>
    <name>X0DTR1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DTR1"/>
    <dbReference type="HOGENOM" id="CLU_037053_0_0_1"/>
    <dbReference type="OrthoDB" id="5273928at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="378" mass="42333" checksum="7722C8F6ED16A0E1" modified="2014-05-14" version="1">MDGGDDKNLGLYRFRQHICHPGNDLTRYTQPLTAPPSDFITHIVIAGGCTFNTHDLLGLADMPNLGVLEIIQPTERTAFPNISDRLVRGWSEKPDPFPLLRVLRIWGDETTSKASLQWVSKFPSLAMYDVIGARDSWDASKVAAQEHGWEQADAPPHRLDDSLLRYLMLFVPLEETRDRNLRDLAASIDNDLVSLCSDSRCAVKFVQDRQAPLLLNYLCDTAKENTPWWDTDAASREARTCHGVAFEAWAFWLYSFLGQLCSDQDLEARGALPYTYKAVAGPFILPSRPIACLHLGHTSQRGGIDTRPSYISRGLFATRQFTFTRKSVIQTSNGKKPATIPKKGVNLVCSERSAPMLATRKAKRKRVVDVLEDMGLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0DY74</accession>
    <name>X0DY74_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_01756</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DY74"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000065">
        <property type="entry name" value="B-cell CLL/lymphoma 6, member B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001781">
        <property type="entry name" value="zinc finger protein 496 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="370"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="398"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="208"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK99117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="452" mass="47620" checksum="63049E3D02A6B21F" modified="2014-05-14" version="1">MSMEGASFSSRRPAAGALPAMTLPPPTADVPSMAKYPFYPSFTGNSSESFQCSREGESVGYSYPPSYSPLPGPFPDRRISSSPSILTPSPGASDGLSPSLSSVNTGSSQGSQAPGNMYQYAQLPAAWATPSNSSYTVSSATQAQPALGQQHFPGRNHSIYNQGPGMHQYNHPRSSQSPATGGDGLPAPPYDQVHQPFQTAVSGGGGQTTPPGLSTSQQTQGAILTSQSSVATQPPTPSSVSAHVDSYTHSRPPSTPNYYTSSASQPSSYPPYGHQPSPTQHSSSNGGPVPRGLGSISGQPHGAGMAPPGPYRSYAPYQTLPTMGGSVLSNIHQPGSQMSMIPGMPVTAYGHPMLYGGQGQPPPTQSERPFKCDQCVQSFSRNHDLKRHKRIHLAVKPFPCTYCSKSFSRKDALKRHRLVKGCESKANENPGDGNGADRSGEENDSPEVKREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0E018</accession>
    <name>X0E018_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription elongation factor 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_00127</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ELOF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E018"/>
    <dbReference type="eggNOG" id="KOG3214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105983_0_0_1"/>
    <dbReference type="OrthoDB" id="445983at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.190:FF:000001">
        <property type="entry name" value="Transcription elongation factor 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007808">
        <property type="entry name" value="Elf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038567">
        <property type="entry name" value="T_Elf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934:SF0">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05129">
        <property type="entry name" value="Zn_ribbon_Elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="84"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK99677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="119" mass="12826" checksum="678F1255507F6CBB" modified="2014-05-14" version="1">MGKRKSSSKPMGPKKKDPLPTTFACLFCNHENSVSVKLDKKAGVGQLDCRVCGQKFQCAVNYLSAAVDVYGEWVDAADAVAKEDNAEPGYTGTSRAGAGRGNRTAVDEDDDEHYGEDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0E220</accession>
    <name>X0E220_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_00571</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E220"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF84">
        <property type="entry name" value="VACUOLAR MEMBRANE AMINO ACID UPTAKE TRANSPORTER FNX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="444"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="511"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="52"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXL00363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="541" mass="57539" checksum="BCB3A099E5B490A0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0E3T6</accession>
    <name>X0E3T6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E3T6"/>
    <dbReference type="eggNOG" id="ENOG502R8TH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064536_0_0_1"/>
    <dbReference type="OrthoDB" id="5379420at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="219"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXL00938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="360" mass="40612" checksum="9F4805D436E54E05" modified="2014-05-14" version="1">MSTAKLHVKPRNVYQLLRGDFTLPLAPVAQSSPHRAALSTSRISNSVGYQTRSYATPKGARKPLRPPPRAPKLVKTQPSSSLQTDFDLSQISPMDFELAMRASENQVGTLRPDEYYEYASKFSNAIRKGAYPSRVNLSENQIPVEVAHEMACLLWLFRRMKAHSSFSMALWASASELNYNPAVVSLVSQLFASGSWRKITAFADVENRFMKLVAEAKNCNALTVYGEYLFQDGKYDQAVAMLNQALDVDDGVFEWKRKCLTCLAKSYAKLGKVHEAKKTLELLGDPEADAELDQLLRSSDAEMTRQQMYTDAVKGKHDLYSQLAEVEFERETKEMDVELKKNHHLWGLEWSRLADPGAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2I7</accession>
    <name>X0B2I7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19267</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979678">
        <property type="protein sequence ID" value="EXK75971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2I7"/>
    <dbReference type="HOGENOM" id="CLU_077468_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="227" mass="25668" checksum="5B3025616AF013FC" modified="2014-05-14" version="1">MAQPKAPAEELKARLTAMSPESHSKFFREILVTLKPVFVSREPNSSKFGYYVPNVPMQDALAICQAVNEREANSIFYSSNHFNAVDSHITRETSDLKAFLDFLSPCYSSLLSSISISFPILQAEQGQSQERKLSLDGLQCLKLLQTSCTKLKTLELVVHPSNSFGLARNAPIYLRLKDSLSRVNEELRRISLLEKVTVRCFGNLDPEVEKLMKGFDWEVDTDQCKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3W6</accession>
    <name>X0B3W6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_18454</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979441">
        <property type="protein sequence ID" value="EXK76820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3W6"/>
    <dbReference type="HOGENOM" id="CLU_055491_3_6_1"/>
    <dbReference type="OrthoDB" id="9985472at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK76820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="14435" checksum="71870C757CE52454" modified="2014-05-14" version="1">MSSGHCLCGGVKVEVSGDPVAVVLCHCLDCRKTSGSTHGLNWVVPGDLVQLEGPSKTFTKLSKAGNPVTNTFCPTCGTTVFRDGPAAPGIKFVKAGIFDDPELLATIKPQGEIFVSRRPVWMSPIEGASQKKEMME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5I2</accession>
    <name>X0B5I2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979424">
        <property type="protein sequence ID" value="EXK77021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5I2"/>
    <dbReference type="eggNOG" id="ENOG502RNNY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_915378_0_0_1"/>
    <dbReference type="OrthoDB" id="5038058at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="301" mass="34124" checksum="2F57E516F2AD402E" modified="2014-05-14" version="1">MEFPRSLDVYRDDNLIIQDFDGIFALPRPLPPLSTDTLVKCIFDAYRNSIKVRLMALTDITPSLCVVGPIESIEAGMVAMVVASEVEYYKLLRSNPGGGQPQSDALSIFPLYKDSFNLIENAGTVILAWRFYGVDDSLFMDRHGQVLPLKANTHPDLSYPSQQSSTPRGENSDAAEIKTLRLELGQVRAEALNNRILKEYMQVKWLATIHNAEDQVSERRTAELIKKCIAKRFEQAQKKHGKQQKIVRLATEKHVDSKAEEMTNDKDDEATRPFTKYDYDVFLKTLFAAVHAIQKDEEKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5S6</accession>
    <name>X0B5S6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979386">
        <property type="protein sequence ID" value="EXK77485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5S6"/>
    <dbReference type="HOGENOM" id="CLU_1337572_0_0_1"/>
    <dbReference type="OrthoDB" id="5103944at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="23115" checksum="4C652B03AA08EE24" modified="2014-05-14" version="1">MTNRGGRPKLHGIDEYFRPASEEGFTLNRVVCKLCSKAMAKHTSKQLRHLHTQCTAYRQLHEVIPSRQPLINTKLDSVSKASKDALDRQAAVAVFTSGKPYSLYEEPETLKLLQMLNSAYEPPDRNRVASFLDPVYLDYQQRVKALLDEAPHLNVIFDASDDISSNRIINISIEIPSSVAFYWTTIDTKDHDHTALTTLSLNAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8N8</accession>
    <name>X0B8N8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_16814</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the secreted LysM effector family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658516">
        <property type="protein sequence ID" value="EXK78520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8N8"/>
    <dbReference type="HOGENOM" id="CLU_010591_5_3_1"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF18">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936192" description="LysM domain-containing protein" evidence="5">
        <location>
            <begin position="25"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="221"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="272"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="478"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="422"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="422"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK78520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="528" mass="56741" checksum="6E5F508312F38DA5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-10-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8Q6</accession>
    <name>X0B8Q6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-octaprenyl-4-hydroxybenzoate carboxy-lyase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658542">
        <property type="protein sequence ID" value="EXK78151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8Q6"/>
    <dbReference type="HOGENOM" id="CLU_2654564_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046281">
        <property type="term" value="P:cinnamic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033494">
        <property type="term" value="P:ferulate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1670.10">
        <property type="entry name" value="UbiD C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049381">
        <property type="entry name" value="UbiD-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="3-OCTAPRENYL-4-HYDROXYBENZOATE CARBOXY-LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108:SF17">
        <property type="entry name" value="FERULIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20696">
        <property type="entry name" value="UbiD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143968">
        <property type="entry name" value="UbiD C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-octaprenyl-4-hydroxybenzoate carboxy-lyase-like C-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="76" mass="8833" checksum="38326CE4463DB0E0" modified="2014-05-14" version="1">MLMNRILMIEDDVDIHNWGNIMWAYTTRCRPGQDEYVFENVNGLPLTPYMKYGHGNPSKGGKMISNCLFPMEYEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BA39</accession>
    <name>X0BA39_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658486">
        <property type="protein sequence ID" value="EXK79030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BA39"/>
    <dbReference type="HOGENOM" id="CLU_000288_125_3_1"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="385"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="863" mass="96455" checksum="2617F6938BB85EC1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BA43</accession>
    <name>X0BA43_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_19572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979950">
        <property type="protein sequence ID" value="EXK75663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BA43"/>
    <dbReference type="eggNOG" id="ENOG502SFVU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_12_1"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF28">
        <property type="entry name" value="PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="33"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK75663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="156" mass="17604" checksum="E54ADA1CCEDF0443" modified="2014-05-14" version="1">MSGTDNKVSDVSTQTVPSSRGLEEANSWAEDAEYLLVDDNKVNMKLMKHHFDKLGLKYNIAWNGQEVVDMYKAHPEQCKMILLDISMPVMGGMQASLLIRQHESENNLQPAIIVGLVAGDIATENRRMVDEFGMNTTFKKPIRLEGLRELVDNWPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAK9</accession>
    <name>X0BAK9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658787">
        <property type="protein sequence ID" value="EXK75863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAK9"/>
    <dbReference type="HOGENOM" id="CLU_2573963_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="81" mass="9592" checksum="0D042C81DE490E97" modified="2014-05-14" version="1">MSGPLARRHTDNDTWHNSQSRIWKPNKATTSHHTNSRAFVVQVQRHQEHPRALWWPQALRRATKRRRSPSIPDQDHRENGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB55</accession>
    <name>X0BB55_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979913">
        <property type="protein sequence ID" value="EXK75694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB55"/>
    <dbReference type="HOGENOM" id="CLU_095933_0_0_1"/>
    <dbReference type="OrthoDB" id="2402916at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="174" mass="18717" checksum="EDDEA7B9182F9795" modified="2014-05-14" version="1">MGGPRHLTARVLDELIRIVQLVPRGDDGINCGNSTELQCLECPDGERCQYTVPLYCAQCATSASRKDAEAEAEKGGGGLTIGGIVGGIIASIVIILAATYLVWRFYIKPKRSQGPTSIHVEDVDLMQGSKKDAVSRRTSLLSMHTVHSTAPTILTRASNVIQIAYIPALPTERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBH6</accession>
    <name>X0BBH6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pisatin demethylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_16236</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658481">
        <property type="protein sequence ID" value="EXK79131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBH6"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000050">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF190">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="58871" checksum="944D67FC4C694506" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC35</accession>
    <name>X0BC35_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658474">
        <property type="protein sequence ID" value="EXK79346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC35"/>
    <dbReference type="HOGENOM" id="CLU_1434195_0_0_1"/>
    <dbReference type="OrthoDB" id="3621332at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935631" evidence="1">
        <location>
            <begin position="25"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="179" mass="19583" checksum="D2C675133C899915" modified="2014-05-14" version="1">MPSFAKAIPTSLAVIAAYAQWVNALGCYSGGLGFNNLHGGDNNNDLTEEVKKDIHTTCTKAAGKTIKPSEPFWLCTNWERNQSPNPDCFSNCIDGCNALDENVRWGCLLGCDSNCGAIEGGFNHIDWAIEVRDSQAEKAISYEQCSEAFNTELGGCHAGSEQNHFDLWFRIDPNRDACP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCJ7</accession>
    <name>X0BCJ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_15563</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658455">
        <property type="protein sequence ID" value="EXK79885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCJ7"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_353749_0_0_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK79885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="794" mass="87901" checksum="8F28883EBB1B47D5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDF3</accession>
    <name>X0BDF3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_18421</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658673">
        <property type="protein sequence ID" value="EXK76853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDF3"/>
    <dbReference type="HOGENOM" id="CLU_064755_0_0_1"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="263"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="234"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK76853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="383" mass="43477" checksum="A4B23B9CE289C6AB" modified="2014-05-14" version="1">MQFELDYQLDMDDSFSLCSQPMPRPSTTTNFSSASSAYDPFIPTSRRSTPHEFGNMHFGVPYNSVSYRTELTLSSSAMGKFMFGLVKTEPEHMSFRDTLPDTPMKREQLGFEFKYMMDMNVTRHGPMGSLTPSNSFGTYGYSPDASIGAASFMMTPTQSLSGSEAAETGSSWSCANYRPISFFPNKQLFSGFVSFDLDRHSQSPLGYSLHEPMSPSRMRAQREMMVEIQQKSPKLQKPKIQSSRKRSIKSGPGQADVVRRAMCKCDYPGCHKGFRRNEHLRRHKQTYHGEGPNRFSCEFCRKDQFNRQDNLNNHRKLHARPNSRNRGVEFIPAAVPVIEQEERSRKRRACSKPHTTEEAMEGEEDSLQIAGVPCLKANDAQCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE64</accession>
    <name>X0BE64_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658444">
        <property type="protein sequence ID" value="EXK80445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE64"/>
    <dbReference type="HOGENOM" id="CLU_618260_0_0_1"/>
    <dbReference type="OrthoDB" id="10634166at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="443" mass="47748" checksum="23B38A924102124C" modified="2014-05-14" version="1">MPSNGPQEATVAGSGSAQRFYGQSTAQSVQNVQAQSNYISDPIQGHRGGLDGSGQSFSGEQTPSTPSSKLPSGTVFVAEAGIVGAAALTSYLAAIDASSSSDTSDAENAHFNGSREDSAGHWDDEFDGLSSDHQQPDHDNSDIEGVHSAASLTNSDDEEASGHVAEGYNVSQPDSLSHYGEVHRDLFSGFDVQNDLHEHQLQSYENSDNELSHEAMEGNSYKQSSGDGEDDEENVQPHDSDSQEESFDNGVESGPEDGHSVNADFLKPSDDNQLDNFALDIYSDVSSHHSAEVEVLSQDEDQDQDQDNNSSDHGFYNESENEESDQESSPDSEQDMQGDTEDDLDAESSQEDSGHETESEAAQNSDQSQENESDQNSDDGNGSDPQSSYPSEDDPEDSPEEEDDESTEEEQSDPEPDDSEDMSEPEEWSYSDSGGDDNAFYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEH7</accession>
    <name>X0BEH7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658449">
        <property type="protein sequence ID" value="EXK80196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEH7"/>
    <dbReference type="HOGENOM" id="CLU_009782_0_1_1"/>
    <dbReference type="OrthoDB" id="6503935at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF2">
        <property type="entry name" value="B, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="1">
        <location>
            <begin position="396"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="838" mass="96572" checksum="0B43B960F2C1FE4C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEM5</accession>
    <name>X0BEM5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979338">
        <property type="protein sequence ID" value="EXK80251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEM5"/>
    <dbReference type="eggNOG" id="ENOG502RZFD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021587_0_1_1"/>
    <dbReference type="OrthoDB" id="5404323at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="567" mass="63299" checksum="BA9F18D185A401BF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF93</accession>
    <name>X0BF93_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658637">
        <property type="protein sequence ID" value="EXK77144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF93"/>
    <dbReference type="HOGENOM" id="CLU_015634_2_0_1"/>
    <dbReference type="OrthoDB" id="5359231at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="613" mass="69574" checksum="935B16AE54861F1C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFA3</accession>
    <name>X0BFA3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_18131</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658635">
        <property type="protein sequence ID" value="EXK77154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFA3"/>
    <dbReference type="ESTHER" id="fusox-x0bfa3">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_3_1"/>
    <dbReference type="OrthoDB" id="6846267at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="9"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK77154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="565" mass="62130" checksum="026E1186D0570216" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFJ5</accession>
    <name>X0BFJ5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658631">
        <property type="protein sequence ID" value="EXK77224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFJ5"/>
    <dbReference type="HOGENOM" id="CLU_2291772_0_0_1"/>
    <dbReference type="OrthoDB" id="5114000at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="101" mass="11619" checksum="758466353EC38579" modified="2014-05-14" version="1">MDPGYRPSSSLYSDEPFFLENLVFSPPPILLGTDAHTDMELVNKIELLQSEVDSLRTDWTPTYKFFELSAGLACHMELIFEDAKERITLERNKWLANCTAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIX3</accession>
    <name>X0BIX3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658521">
        <property type="protein sequence ID" value="EXK78414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIX3"/>
    <dbReference type="HOGENOM" id="CLU_2210188_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="107" mass="12225" checksum="3F8B87AA50277777" modified="2014-05-14" version="1">MANTGESSITLHPFPGSDRETRPHRNRHPPKKYPHKEIGRCATTGLVLLRKRQYGTKIKTGEGRFLTAFGYGGDRALWGWIVETQPLNCLVAKELEPNWALRHVYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJV3</accession>
    <name>X0BJV3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13153</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJV3"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_0_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF272">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK82440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="328" mass="35896" checksum="B4575302404F00C4" modified="2014-05-14" version="1">MADRYVTIHESPNGPGDSRPTAIQIIKDEGLEGKLSDQTVFITGCSAGIGIETAKALHLTGATLYLTARDLEKAKSALGDLVEDERVHLLELDLESLESVRSCAAKFLSESPKLNILICNAGVMCTPEGRTKEGFETQFGTNHLSHFLLFQLLQPALAKGATSDRASRVIMLSSLAHRFGEVDFDNVNMEGCYDPNKAYSQSKTANLWTANEIERRYASKGIHAWSVQPGGVLTDLGRHLSEEQKSRLAVDPYLKTIWKLPNQGAATSVWAAVAQALEGQGGKYLEDCQIVGKWDPSTPLYARGYGEHACDTEKAARLWDKSLEWVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMM8</accession>
    <name>X0BMM8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMM8"/>
    <dbReference type="HOGENOM" id="CLU_146844_0_0_1"/>
    <dbReference type="OrthoDB" id="437457at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="111" mass="12833" checksum="700D26FB1C076FA9" modified="2014-05-14" version="1">MHPEIDSWKSDMKERYEEQKQRHPEYGRDALIIHALTRDYAIEGKILKHAIRVASWQPPNGIKGHLESFNETVLAHPLGGMLDGRFYGPIVAVTYHLDPEFNYNRVSTADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMX3</accession>
    <name>X0BMX3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMX3"/>
    <dbReference type="HOGENOM" id="CLU_093223_0_0_1"/>
    <dbReference type="OrthoDB" id="5148387at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="231" mass="24950" checksum="0C09783380A1E25F" modified="2014-05-14" version="1">MWVTPGVLTEYMAEATLVAEGTGAAATEGAVEAVAPEVIEAVAANRTFWQSAQAFGKWVAKEAVELSLLQAGARAFEAALDTIAKKNDDKDAERLAKAMPNINEALKKANDCVSDWNLWMSHHFDTRAQYGVIQVDGHKFSLLEVFQAQISTVSLCLTQKAYPATGVASQSMTLNTAKLLVSSLQEYCQKLKVISIRIKDKEQKMVAAGLNDHVGDVDTAITDLVVSANSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNL3</accession>
    <name>X0BNL3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNL3"/>
    <dbReference type="eggNOG" id="ENOG502T4X5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1185051_0_0_1"/>
    <dbReference type="OrthoDB" id="4774241at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938740" evidence="2">
        <location>
            <begin position="18"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="234" mass="24035" checksum="FB76B398BD780C27" modified="2014-05-14" version="1">MKATFFSVFALAISAIASPVPEVQKDTRSVEQVNGAIHSAENIVSKVGVKQIVDEATKSPAKRAAISNPQELITVLKSGVSNINKKTTGLNSIAEKVKAGDLTKDAGATKAIPGFESVHFELTEIVTKLTGAAGLDVADSDVDTVLNLVVVLVSEVLTAVKTIVTVTGLRPQLISILHSVFQILTKVLVLVIGLVSAIVPGLVAGLTPLLAGLGNGVLAPVLLPITGLLASLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRH7</accession>
    <name>X0BRH7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Aquaglyceroporin like protein, other eukaryote</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_11497</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>glycerol(in) = glycerol(out)</text>
            <dbReference type="Rhea" id="RHEA:29675"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRH7"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1080.10:FF:000027">
        <property type="entry name" value="MIP aquaporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="25"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK84481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="388" mass="41940" checksum="2D6D1843DBDD03AA" modified="2014-05-14" version="1">MLDDANPLSVTCLSCIRQTSPLSISRSSSQAHSRMPIPTMNDSISESSVHKSSIPTKVEMSQNEKYSEAPSEPPTIPPPPEQYAWSRVREYCQDAFSEFFGTFILLLFGDGVVAQVVLSRGTKGDYQSISWGWGLGVMLGVYVGGKSGGHLNPAVTLANCIFRGHPWRKFPVYAVAQVLGAMCAAAVVYGNYKSAFDAYEGGPGIRTVIGENATAGVFCTYPAEFMTRTGMFFSEFIASTILQFVIFAMADSANIGAGPLMPLGLFFLIFGIGACFGWETGYAINLARDFGPRLVSYMIGYGSEVWSAGGYYFWVSPTTIPRLSTSTDSEIQIPMVAPFMGCAFGGLLYDVFIYTGPSPINTPGMGLPRLLSPRRSTWSNTYSASSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS90</accession>
    <name>X0BS90_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658422">
        <property type="protein sequence ID" value="EXK81783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS90"/>
    <dbReference type="HOGENOM" id="CLU_943457_0_0_1"/>
    <dbReference type="OrthoDB" id="5104709at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936528" evidence="2">
        <location>
            <begin position="17"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="325" mass="33540" checksum="C5AD991CB15E934E" modified="2014-05-14" version="1">MRFYASFSLAFGLVAASPCKPLTSGSTAVSATFSSSATEISNTFAESATSTVETLATETSTVIESGTSTAIDTTATEASTFVGSTSTETTDATISAPETSSQATSGTALFTSVTSADATTTVTTETSTAETSAATTTTVETSTAMTATTTSEEPGPTDHLLIAGQGSAQGLPLKTTKQNGDYMIFGERSSSWTVGRFVVDPTTGYLTRDGIPVCAKYHYMDRRASLTLCSTEYNLYGTARLTCARNPAAGTALQCSAVKLDCVSSGPGDNQRCSVSTEANWTKFFISVSSDYTVYLGADDLAVSYLASVDIFVDRAPTAAAPTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSE0</accession>
    <name>X0BSE0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSE0"/>
    <dbReference type="eggNOG" id="KOG0590">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002639_7_0_1"/>
    <dbReference type="OrthoDB" id="5125733at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="165"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1121" mass="127562" checksum="BD3009F6301EB9E0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSE3</accession>
    <name>X0BSE3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSE3"/>
    <dbReference type="HOGENOM" id="CLU_007526_0_2_1"/>
    <dbReference type="OrthoDB" id="191037at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF1">
        <property type="entry name" value="HAD FAMILY PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="378" mass="42647" checksum="89575118B1914019" modified="2014-05-14" version="1">MAGAVRQPIDIARLSAYIEQNVDQISLPISLKQFGHGQSNPTYEVTSATGLKFVLRKKPPGKLLSKSAHAIEREYEIIKALEVTDIPVPKLYCLCEDVSIIGTPFYIMAFLDGRIFEEPWLPTLSPEERTLIWKEAVHTLAKLHSVNLTGIGLHSWKRPTSFYTRQIKALSKTSEAQASTASQPGAQNVGKLPYYDQLISFFTDHKTHPPDVRRLVHGDFKLDNLVFHKTEPRVIGILDWEMATEGHPLSDLANLLMPFSWEPQQVPFLTSETLTSELEELQSKFQPCNVAGIPSMEQCQEWYWGGVDWDAAGYLDWGVAFSNFRTAIVMQGIAARIVRGQASGSKAREFARQTLAYASWGYARVEKLQQRLRLRSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BT08</accession>
    <name>X0BT08_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BT08"/>
    <dbReference type="HOGENOM" id="CLU_144283_0_0_1"/>
    <dbReference type="OrthoDB" id="5216128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025363">
        <property type="entry name" value="DUF4267"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14087">
        <property type="entry name" value="DUF4267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14080" checksum="3803B0190FD9A575" modified="2014-05-14" version="1">MSFIYLNRATHVVSLIPALFGINLLTRPEATLQSFQYPIPTDPKARKLVRGITRIYGCRNLVISFLFFNISLTGNRKLMSLGYLGALAMCVTDGLVARNVVGHGEWQHWSFAPLCIGLLIGLNWQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTQ1</accession>
    <name>X0BTQ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trihydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_13743</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cerato-ulmin hydrophobin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTQ1"/>
    <dbReference type="eggNOG" id="ENOG502SUV9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141181_2_2_1"/>
    <dbReference type="OrthoDB" id="4500971at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23508">
        <property type="entry name" value="hydrophobin_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.120.10">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010636">
        <property type="entry name" value="Class_II_hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036686">
        <property type="entry name" value="Class_II_Hydrophobin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341:SF1">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06766">
        <property type="entry name" value="Hydrophobin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101751">
        <property type="entry name" value="Hydrophobin II, HfbII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938850" description="Trihydrophobin" evidence="4">
        <location>
            <begin position="18"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK81874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="10109" checksum="1E6FDE37E451B0AD" modified="2014-05-14" version="1">MQFSLAIVTLLATAVSALPTEEKRQAYIPCSGLYGTSQCCATDVLGLADLDCGNPPSTPANATDFSAVCSAIGQRARCCVLPILDQGILCNTPTGVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUH0</accession>
    <name>X0BUH0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUH0"/>
    <dbReference type="eggNOG" id="ENOG502SKSW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_969932_0_0_1"/>
    <dbReference type="OrthoDB" id="422736at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="272" mass="31543" checksum="36C8CD5C857ABBFC" modified="2014-05-14" version="1">MRRMFRRAKQKIEAMVGEAFPVRSEQGMIGDLIGAQEIWRELQRNNHVSVDVKDFVGKNYEFHAGLDYAQEISVQTFATEISPENNIFDGDFVMLSDREPIKMNSEIRGISPVRVKDVPDDLKPVSSPLVEHGKTVDWSDMPLYTDFFLSTVPAMLHHNEYKERRATWWDRPWYHQKLRGLVKYALLPRGADEPLATVQLEGSRVRYWAASAEEMDRYPRMGKLNANLTAYDRFPKMEPNETCRYGSRKPRESKATWEEEVFRDGGGEFNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUZ7</accession>
    <name>X0BUZ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphotransferase</fullName>
            <ecNumber evidence="11">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_10487</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:16126"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a D-hexose + ATP = a D-hexose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22740"/>
            <dbReference type="ChEBI" id="CHEBI:4194"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:229467"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:22741"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the hexokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUZ7"/>
    <dbReference type="eggNOG" id="KOG1369">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014393_5_1_1"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019158">
        <property type="term" value="F:mannokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.367.20:FF:000004">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF16">
        <property type="entry name" value="HEXOKINASE TYPE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="12">
        <location>
            <begin position="8"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="13">
        <location>
            <begin position="208"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK85696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="456" mass="50629" checksum="2139D520149DA5D4" modified="2014-05-14" version="1">MANLQTYLQELERDFTVDTAKLKHITNHFIDELDKGLSAKGGSIPMNPTWVMQQPTGNETGKYLVLDLGGTNLRVFSVELTEQKSGFKVNQVTHKLPKELRTGPAERLWDFVAGHLEEFLKTADFEAGTNTDLSFIFSFPTTQRTIDEGILQRWTKGFDVADCEGRDVAASLRHSIAKRKLPLKVRVVTNDTTATMMASAYINSETAIGCVFGTGCNGAYFERCQSIPKLDMEGLPAEALMAINCEWGAFDNEHVVLPLTSFDIAIDDASPRKGQQAFEKMVAGLYLGELFRLIMLDVKRRHETFWEGQSVEKMQEPYFMDSSFLSAIEEDTSKDFKTSHDLSVSKLGVSPNVHELEFMRKVATLITTRAARLSSTGVAAICMKRNLKTCHVGVEGSLFEKHPHFKRELSKALGEILGWEKLSPTGKDDVEFMVSPGSGVGAAVIASTLTRSKHEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV75</accession>
    <name>X0BV75_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_13278</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV75"/>
    <dbReference type="HOGENOM" id="CLU_007426_4_0_1"/>
    <dbReference type="OrthoDB" id="9996127at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="626"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK82409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="703" mass="79274" checksum="13E06EB12FF5DC11" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX51</accession>
    <name>X0BX51_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX51"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:001190">
        <property type="entry name" value="Short-chain dehydrogenase/reductase SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF122">
        <property type="entry name" value="NAD(P)-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="283" mass="29116" checksum="D35BF85A6A650922" modified="2014-05-14" version="1">MAEIPTQPPSRSLKDKVAIVTGAGCFGDGIGNGRAISIMLANEGCNVICLDMDLEWATKTADMANQSSASKKAIPAQGNVTDADDCEKAVALALEEFGRLDILVNNVGIAGASGTAIDVDMAKWTMGLEVNVSSMVLMAKYAIPAMAKNDGEIKGSIVNMGSVAGLKGGTPHLLYPTAKGAVVNMTRAMAAHHAKDGIRVNCVCPGMLYTPMMYAKGMSEEAREARKARSLLGTEGTAWDAACAVVFLASNHARWITGAILPVDAGTTAAVGTSLPAGASVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZJ1</accession>
    <name>X0BZJ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein PLANT CADMIUM RESISTANCE 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19288</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979689">
        <property type="protein sequence ID" value="EXK75952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZJ1"/>
    <dbReference type="eggNOG" id="ENOG502S7UD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083147_2_0_1"/>
    <dbReference type="OrthoDB" id="1045822at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15473" checksum="B7E9396FC79BBDEC" modified="2014-05-14" version="1">MSQEWENSLFDCSPCDSCLLSTFLPCILFGRTSHRLQNPSAEPESFNSDCALFCGIQSLTGCGWIFNVMKRGEIREAYGIEGSGMGDCCASFWCLCCALIQQEKEVKSRQLACCETAGYQPMKDGMHVVGQGEADKELQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZJ5</accession>
    <name>X0BZJ5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZJ5"/>
    <dbReference type="eggNOG" id="ENOG502RNHR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013866_5_2_1"/>
    <dbReference type="OrthoDB" id="5429770at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF1">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="47800" checksum="460A4A081CA7D6D9" modified="2014-05-14" version="1">MLTSNELVFRDETRNTMQKVLARRAASWLPSAPQFSPDTSSRNAFLSLYIDTYSCGFYTLQSLLTDSAPNGHLQVSVDAVSLAFMAYQLNCQDLLPLANQRYLAAIRSLGIVMRSSLQANHAANQSLTDETLQSVLLLDLYEKMAYQPHSESEFPGSWLSHVHGALSIVRSRPTAEFSNPTTQQLATRTVIALTLSCGAAGIPIPEALIGLYNDLDSYVRSAKWTFIGLLISLINLRADMNRGKLESSDIVQRARDLYEELSHAEGKIPRSWWPQRRDTSEAVVFGGYYDVYPGHYTTQVINAYRIMRLDVCSIIQKFDPSSEVAETITEVAQAICAAVPQFILPGARSQNTLPFSPLQILECSGLLTPLYAASQNTQDPVMRAWILRTLVYMADNGIKLAQSVAQVIMFLPDMDYWAVFRMVGNCAITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZN7</accession>
    <name>X0BZN7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK83984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZN7"/>
    <dbReference type="eggNOG" id="KOG3968">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_2_3_1"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050287">
        <property type="entry name" value="MTA/SAH_deaminase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006056">
        <property type="entry name" value="PRK08204.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794:SF11">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794">
        <property type="entry name" value="AMINOHYDROLASE SSNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="63"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="478" mass="52496" checksum="E4BEF800630C9C5A" modified="2014-05-14" version="1">MSETSSPNLILIKNATVLTVDPLTGTLANSDILIQDDRIVAIGQAQPNPSEGNVTKIDGQGCIVTPGFVDGHHHMWQQLLRGVATDWSLFDYTVNMRTIYGSLYTPEDVYLSTYVAALSLINNGVTSVLEHCHIINSPDHADAAVRALQDAGIRGTFCYGFYANPPLPDQLDPRGFSHAPRLSDAARIRDKFFGQNDPAEQLLTFGIAPDEPESLPIEETIAQIKQSRELGARIITMHVAMGPYDLARRQVVQNLADEGILGPDLVFSHGSSFTQSELQAIKESGASIVGTPDTELQMGMGFPIVFQASDRGCRTCLGIDITSNQGNDFIAQMRLALQARRAQENEQGFPLSINRKTADVLRMGTLGGAEVMRMEDLIGSITVGKKADLILVRCDDIENTPVGDPVGSVVFHSSVKDIDTVIIDGKIKKRKGKLTVDWERLRKEVIRRADRIKDYAATIDLTEARKRWMEIFHVKDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZV5</accession>
    <name>X0BZV5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZV5"/>
    <dbReference type="HOGENOM" id="CLU_136323_0_0_1"/>
    <dbReference type="OrthoDB" id="5100830at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="166" mass="17733" checksum="D8C8426D990EDC31" modified="2014-05-14" version="1">MIFPETHTVDTTNTATVHVSANTATSTVDTLSAATTSTTDATEITTTADATTAESTITSDLTTSVSVSEPFETFDVLAIGGSINAQYMKGVANEGSVMGWDLTGTGTGHMPPFTIKPGTNYAEVLRNDLYLCIGYGDGSEPNFVASCEPFYQRRPFHRVPHMRVDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0R5</accession>
    <name>X0C0R5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(+) ADP-ribosyltransferase</fullName>
            <ecNumber evidence="2">2.4.2.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_18860</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>NAD(+) + (ADP-D-ribosyl)n-acceptor = nicotinamide + (ADP-D-ribosyl)n+1-acceptor + H(+).</text>
            <dbReference type="EC" id="2.4.2.30"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ARTD/PARP family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.30" evidence="2"/>
    <dbReference type="EMBL" id="JH658725">
        <property type="protein sequence ID" value="EXK76397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0R5"/>
    <dbReference type="HOGENOM" id="CLU_1023240_0_0_1"/>
    <dbReference type="OrthoDB" id="2017365at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990404">
        <property type="term" value="F:NAD+-protein mono-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070212">
        <property type="term" value="P:protein poly-ADP-ribosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07997">
        <property type="entry name" value="WGR_PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.140.10:FF:000001">
        <property type="entry name" value="Poly [ADP-ribose] polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.140.10">
        <property type="entry name" value="WGR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050800">
        <property type="entry name" value="ARTD/PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008893">
        <property type="entry name" value="WGR_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459:SF60">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05406">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00773">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="WGR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51977">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WGR" evidence="11">
        <location>
            <begin position="101"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="31"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK76397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="272" mass="30655" checksum="B2D7483B35D21E52" modified="2014-05-14" version="1">MAYRPSIKSQRLVDRCLFVGEQHTEIDIREKSPEKTKKGVRVKDGVKINSDLTNTSDVTAKPDPKGNVGDRGRPKNVVPKNKPIKRKDVVIPLDEHCTLGTYKVYVDPKTGLIYDASLNQTVSSTNKNKFYNIQVLKDPESSDCKTWTRWGRVGEVGAYAILGNGTVTDAIKQFHKKFKDKSGLAWNNRKDSAKPGKYVFLERRCSPHSDYKGEKSGNKAVKKVAGEQEHEVSPPECSLEKPVKELMELIFNQQCFSNTISALKQAEQENYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1A7</accession>
    <name>X0C1A7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1A7"/>
    <dbReference type="eggNOG" id="ENOG502RYWT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040838_1_0_1"/>
    <dbReference type="OrthoDB" id="5306317at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="348" mass="38624" checksum="4ED12E24DBFB90C1" modified="2014-05-14" version="1">MADAAVPVFFELSWSILMTICMGNVLLGCLVCGITNWTLLAAVPMLSSAAGAVANGLCYYVYYQKHPAMMLAIASVFADIFWLLQEAGLLFYSYIILKRVLRGMRWRVFMSLFWSGIAGICVVRVVIITFRVRSILAGNEDLLATINHIHIAYFGLIASLECLSAYFLIVLFTSAKTSSAEIARNGGLFQYLARSTEMRVALLALQGTLRAVTHSFKTAGQTAENIATQLDRFFYAVFCLYSMVLYIDLLSSKLKFNGTQDYPSSRDRYVHQSSQPGRFTSTQKDDFAQNRTEHVVGVDGGTRTHKTRNDSTDHIIEGGSSQGDGSINLEDMDLKGNVIKKTVEFRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1E7</accession>
    <name>X0C1E7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08825</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1E7"/>
    <dbReference type="eggNOG" id="ENOG502SN12">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006524_7_2_1"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="13"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK87971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="588" mass="66013" checksum="F9B1D6FCEFA6813B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C314</accession>
    <name>X0C314_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C314"/>
    <dbReference type="eggNOG" id="ENOG502SH7Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003772_0_0_1"/>
    <dbReference type="OrthoDB" id="2588159at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053161">
        <property type="entry name" value="Ulvan_degrading_GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36848">
        <property type="entry name" value="DNA-BINDING PROTEIN (PUTATIVE SECRETED PROTEIN)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36848:SF2">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17132">
        <property type="entry name" value="Glyco_hydro_106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936735" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="1026"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1026" mass="113290" checksum="EEEC69A7C7DF6F55" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C602</accession>
    <name>X0C602_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C602"/>
    <dbReference type="HOGENOM" id="CLU_062857_1_0_1"/>
    <dbReference type="OrthoDB" id="3594103at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="195" mass="21651" checksum="519B82A9F34712B9" modified="2014-05-14" version="1">MDPGDTKPPEKSCSELTTAFRAHAAAVDLELTSLQLLASSEMRRLEGESEFSFDIADIEQHRTTTRSVSDNYGKLCIVCHKVISISLREMQREMMNQLGVPENVAMVLANCFLQSKGIGFTQNHDNETGLGDEKALDTSQLAQEERGLLTILQTFDKESSQIYQSTFETGVRQKMARETLARTILETWEAGGGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6H4</accession>
    <name>X0C6H4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6H4"/>
    <dbReference type="eggNOG" id="ENOG502RQU7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050889_0_0_1"/>
    <dbReference type="OrthoDB" id="5040307at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="328" mass="37098" checksum="70149CBD580265D5" modified="2014-05-14" version="1">MSQNRHRSVPKGTGAPLSPPSSQPSANFAPALTASKPFPDVAYSSTQTTPNIPKSEDNQLLKQAEALANMHFELNLHTVFSLASRLEKEVQQLVFRTADDQEFRRQNEERMTKMMIEVQTVKAYMARMGHNHEPATRADIERLQQAMSDTTMEWNNQLEDARTKIDEISGRMINVSRHAGVRGNEPQTSPSLVGIETRAMRKAKTDIISSAHQQQTSPSSSTLESRINDAINSTKRWNREHKTTKMRENQFIISYLKKQGQRDPVLAKVLLQAIRERASNTKTRTSKAKKLPSLEETCRNTSWQDVIDSATEVLVVNKTQTLQFLKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6Y0</accession>
    <name>X0C6Y0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979359">
        <property type="protein sequence ID" value="EXK78487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6Y0"/>
    <dbReference type="HOGENOM" id="CLU_3384795_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="33" mass="3541" checksum="285B199FB9D9965A" modified="2014-05-14" version="1">MRGALDEMISRRACMKVIGRDKACDASISCPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7D7</accession>
    <name>X0C7D7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7D7"/>
    <dbReference type="HOGENOM" id="CLU_2171175_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="107" mass="12226" checksum="9DEB7F7E9E6FA883" modified="2014-05-14" version="1">MNILFSHFPINPPIHRDHTIRSQPRHCTEENKTSSNCITSTTCLFHSTDPSCPLRLLSNGYIRPETLSRHLRIFHDVFVLPSPKTEEILCNQPHCTYSLSLSLPCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8J7</accession>
    <name>X0C8J7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Inositol oxygenase</fullName>
            <ecNumber evidence="4 14">1.13.99.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 14">Myo-inositol oxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_09421</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 14">
            <text>myo-inositol + O2 = D-glucuronate + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23696"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:58720"/>
            <dbReference type="EC" id="1.13.99.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="13 14">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Polyol metabolism; myo-inositol degradation into D-glucuronate; D-glucuronate from myo-inositol: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the myo-inositol oxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.99.1" evidence="4 14"/>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8J7"/>
    <dbReference type="eggNOG" id="KOG1573">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050259_0_1_1"/>
    <dbReference type="OrthoDB" id="5151075at2759"/>
    <dbReference type="UniPathway" id="UPA00111">
        <property type="reaction ID" value="UER00527"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050113">
        <property type="term" value="F:inositol oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019310">
        <property type="term" value="P:inositol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007828">
        <property type="entry name" value="Inositol_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588:SF0">
        <property type="entry name" value="INOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588">
        <property type="entry name" value="MYOINOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05153">
        <property type="entry name" value="MIOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="105"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="164"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="242"/>
            <end position="243"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR607828-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR607828-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK87154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="308" mass="35693" checksum="09283046B5BAABB6" modified="2014-05-14" version="1">MAPGAVVDDFSSHDGQALEVLSDKIDDVNVIKYDETSKFDKEKDKNTFRQYADATDRVKNFYREQHHKQTVAYNLAARNRFYNASRPRAEMTIWEAMEKLNTLVDESDPDTSLSQIQHLLQSAEAIRRDGKPRWMQLTGLIHDLGKLMLFFPELETQGQWDVVGDTFPVGCAFSDKIIYPETFAEGNPDAINPDFNTKYGIYSPNCGLDNVMLSWGHDEYLYHVVKDQSTLPDEALAMIRYHSFYPWHREGAYRHLMCDKDHEMLKAVNAFNPYDLYSKSDGVPDAEKLKPYYMELISEYFPNPVIKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAJ1</accession>
    <name>X0CAJ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_06644</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAJ1"/>
    <dbReference type="eggNOG" id="KOG2740">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017139_0_0_1"/>
    <dbReference type="OrthoDB" id="870at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14837">
        <property type="entry name" value="AP3_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="7">
        <location>
            <begin position="190"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK91146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="539" mass="57465" checksum="41BC0E7979718E2C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB12</accession>
    <name>X0CB12_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658456">
        <property type="protein sequence ID" value="EXK79862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB12"/>
    <dbReference type="HOGENOM" id="CLU_119621_0_0_1"/>
    <dbReference type="OrthoDB" id="3899536at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936274" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="21552" checksum="2260733C3A58F9A5" modified="2014-05-14" version="1">MHFITAALSAHLASAALAVPLNSTPHDNPDSNIFPDFDRYSDWAICKGKITKGRFPNLQAPNRDGGCVRYYRGIDMTGVVTEQHFFFKDGFKTACDCAARCLEEPNKCTNWAWKHTFMPEDGGKRSCTLYSSPNLPTDVTLKYDLANSKGFNLLQAANNPQAGAPAPLTFLDAAGTIPDKFGVSGFMVQDQNGSQFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CC16</accession>
    <name>X0CC16_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CC16"/>
    <dbReference type="eggNOG" id="ENOG502QQ7T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_402257_0_0_1"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WSC" evidence="2">
        <location>
            <begin position="367"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="314"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="768" mass="77561" checksum="E823D1DAA66DAD0B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD05</accession>
    <name>X0CD05_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ahmp1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD05"/>
    <dbReference type="eggNOG" id="ENOG502RQQT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015848_0_0_1"/>
    <dbReference type="OrthoDB" id="3365211at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021369">
        <property type="entry name" value="DUF2985"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11204">
        <property type="entry name" value="DUF2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="409"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="639"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="685"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="735" mass="82924" checksum="8BDFFD28F0461862" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEU7</accession>
    <name>X0CEU7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock protein 78, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_07286</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEU7"/>
    <dbReference type="eggNOG" id="KOG1051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_0_1"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000120">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF176">
        <property type="entry name" value="HEAT SHOCK PROTEIN 78, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="121"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="521"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="9">
        <location>
            <begin position="699"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="334"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK89743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="797" mass="88579" checksum="EAB1A576FCF6644E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFG7</accession>
    <name>X0CFG7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kelch repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_07436</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFG7"/>
    <dbReference type="eggNOG" id="ENOG502RYEQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012508_0_0_1"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019760">
        <property type="term" value="P:glucosinolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435:SF4">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="684"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="75"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="760"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK89983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="841" mass="90523" checksum="D6E88D948249155F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CG46</accession>
    <name>X0CG46_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CG46"/>
    <dbReference type="eggNOG" id="ENOG502RZZS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038616_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="406" mass="43865" checksum="16EDB3EE76D87223" modified="2014-05-14" version="1">MATTQLPSPDTTQLLAPFLPALPPSAISTEPAIGILPLLSPILRQRVKLLSTSSTEPWIRLLCYDKAKIPELIQIAQGGSLEPHPVSGEVEVDWDYDAEVRFRRVDEETLQALVALSTLGLAFQLIYCVGDVEGGGDGWRVGEVTIADKPSPFLQFGGASSIAEAERQFRETQAKKVTNQAKDANGHGHGHGNSLHIPHSGHEEDEEDDDDYWARYDATPSRTPAQKLSPAPPSKSTSQIGGVRASSAEDAYFAQYDSVQPAMDNHDPDEEEAAAQIAPPLGLGRTQESAEATELNETQGAWTLAEIEKSDSSPTQNGDDTERHAALLHPRPASSASSNGSETVAKLEASAGKQTQNEFGVKQHVSRSIRSLFMLSRASGIDRQEFESLVRAELDILGMVEAQEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHB0</accession>
    <name>X0CHB0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosducin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07056</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosducin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHB0"/>
    <dbReference type="eggNOG" id="KOG3171">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053880_1_0_1"/>
    <dbReference type="OrthoDB" id="70588at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008277">
        <property type="term" value="P:regulation of G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02987">
        <property type="entry name" value="Phd_like_Phd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001200">
        <property type="entry name" value="Phosducin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051499">
        <property type="entry name" value="Phosducin-like_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024253">
        <property type="entry name" value="Phosducin_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052:SF1">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02114">
        <property type="entry name" value="Phosducin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosducin" evidence="3">
        <location>
            <begin position="138"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK90184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="290" mass="32604" checksum="32E54E240D7E9161" modified="2014-05-14" version="1">MSTAAQEEFNDLVAKNTYRETLHPEDRDDPDLKNHQDLSEEDVFRNAQIDNAMRMPTVDRLTGAGASEIKLPPVSFDSGRATGVKGVIADARNYEAARKNKWRHRVRTARNSIFGIEAPTPVKSDTESSDDDAKSASDADEEAFLAEWRESRRRELESEASRSVRNRRTSPSVRIYGRLDEVDALGYLDAIEKVGRETTVVVFVYDHECEVSATIESALMPIVKTNPEVHFVKVHYEEIEFDNAAVPAMLGYRNQGDLFANLTGLIEMIPDDETFGTSSLKQLLQKHTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIC0</accession>
    <name>X0CIC0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIC0"/>
    <dbReference type="eggNOG" id="ENOG502S75W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107705_2_1_1"/>
    <dbReference type="OrthoDB" id="5419162at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018824">
        <property type="entry name" value="Conidiation-specific_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052670">
        <property type="entry name" value="UPF0654_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36576">
        <property type="entry name" value="UPF0654 PROTEIN C11D3.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36576:SF1">
        <property type="entry name" value="UPF0654 PROTEIN C11D3.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10346">
        <property type="entry name" value="Con-6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="8979" checksum="A7DD6712AE07E6F8" modified="2014-05-14" version="1">MTDAQAAGGHKATINNPNTSEEAKEHSRQVLENEFNGGEVTGAEDNKDKNPGNVAGGLKATLNNPNVSDEAKKNAKERLDKEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJ80</accession>
    <name>X0CJ80_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJ80"/>
    <dbReference type="eggNOG" id="ENOG502SK3P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072365_1_0_1"/>
    <dbReference type="OrthoDB" id="5282017at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="36458" checksum="49FDC26DBAADC9F0" modified="2014-05-14" version="1">MSQYATTARTLSRAPLAGKAFSPVLPTLGRAAPPYQSKWKRTAPVPLSGKNFLDVLFNRTPVIKQPGFLGREECFAHEKALSHRIAPYRYYTGPLLQRVGCAQFEYQAQAAADFENRKNEKEEYFKVAQSLSGLHQEVADQTGVNAWEKVIGTLRALLPDYEIIRASEGPGKTYFSGNFRALNDSTCLHCDWTPYDAATEDWIINQVTHQAVFNLYMAPVKGGRTWVHDVEWSEECLNFRDPDTYGYRDEIIHGRQNVVVKPEVGDLWVFNSRNMHQVEKVEPEPCPELGLPYRPRLCLSSFIGLLPEHKTGGRPRLILWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CK56</accession>
    <name>X0CK56_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_06359</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CK56"/>
    <dbReference type="eggNOG" id="KOG2571">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012773_0_0_1"/>
    <dbReference type="OrthoDB" id="5321960at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000077">
        <property type="entry name" value="Probable chitin synthase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF46">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="500"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="573"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="705"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK91658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="767" mass="87882" checksum="FFCB70B699223FF1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKY1</accession>
    <name>X0CKY1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_12525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658405">
        <property type="protein sequence ID" value="EXK83172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKY1"/>
    <dbReference type="eggNOG" id="ENOG502RYMZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_13_4_1"/>
    <dbReference type="OrthoDB" id="5819582at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="452"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="3">
        <location>
            <begin position="46"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="3">
        <location>
            <begin position="337"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK83172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="604" mass="68062" checksum="BD8F006FEFB0CDA8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLC1</accession>
    <name>X0CLC1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLC1"/>
    <dbReference type="eggNOG" id="ENOG502T1Y8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123978_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="142" mass="15649" checksum="73439F05172C6D6C" modified="2014-05-14" version="1">MTSNSISQLPTPEQREDITASLADLITAIESHSQWTPPNVDRGLFHVWDFVKRSHYIMTELDNIAAGRKVQHPEQIPKNDGVASGPEAALASYTDVCTRTITINEMIQNPRMLVMLGLSNVDFGSAIQEKSEAVKEAIKSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLG2</accession>
    <name>X0CLG2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_03749</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLG2"/>
    <dbReference type="eggNOG" id="ENOG502QR2H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009768_0_0_1"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF27">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="178"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="88"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="261"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="836"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="851"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK95021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1072" mass="116817" checksum="3C5D90590CBA8AB1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLW2</accession>
    <name>X0CLW2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Uridine kinase</fullName>
            <ecNumber evidence="7">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_06152</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the uridine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="7"/>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLW2"/>
    <dbReference type="eggNOG" id="KOG4203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021278_0_2_1"/>
    <dbReference type="OrthoDB" id="738517at2759"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043771">
        <property type="term" value="F:cytidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002070">
        <property type="entry name" value="Uridine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000010">
        <property type="entry name" value="Uridine-cytidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="8">
        <location>
            <begin position="34"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="9">
        <location>
            <begin position="266"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK92278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="461" mass="52020" checksum="94964AC8FED3A7A6" modified="2014-05-14" version="1">MSASAILEVNGGLESHVTVQKRAYYSPPWADVSIIGVAGSSGSGKSTLSQAIVKKLNLPWVVILSMDSFYKTLTPEQSKLAFANEYDFDSPDAIDFDVLVDKLRDLKAGKRAEIPVYSFAKHSRLDRTTSIYSPHVLVLEGIFALYDPRVLELLDMGIYCEADADTCLSRRLVRDVRERGRDIEGIIKQWFGFVKPNFEKFVEPQRKVADLIVPRGIENRVALEMMVQFVEKKLFEKSRHHREALSRLEAASKDSPLSERVVVLDDTRQLRFMNTILQDIDTDPEDFIFYFDRLASLIIEQALNNAHFEAKNIVTPQGYEYKGLVSTGEVCAVIVLRGGSAFEPALRKTIPDCRTGRLLIQSDYSTGEPELHYLRLPDDIADQESVLLLDTQMATGGAALMAVQVLVDHGVKQDRIVLATYSAGKVGLHRLTSVFPEITVVVCNMLDYQQERWVEKRYFRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMJ6</accession>
    <name>X0CMJ6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="11">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_03980</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the phage and mitochondrial RNA polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="11"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1038">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003364_1_0_1"/>
    <dbReference type="OrthoDB" id="276422at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001018">
        <property type="term" value="F:mitochondrial promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006390">
        <property type="term" value="P:mitochondrial transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000041">
        <property type="entry name" value="DNA-directed RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.280:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="entry name" value="DNA-directed RNA polymerase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024075">
        <property type="entry name" value="DNA-dir_RNA_pol_helix_hairp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046950">
        <property type="entry name" value="DNA-dir_Rpol_C_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00940">
        <property type="entry name" value="RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00900">
        <property type="entry name" value="RNA_POL_PHAGE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00489">
        <property type="entry name" value="RNA_POL_PHAGE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase N-terminal" evidence="13">
        <location>
            <begin position="358"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="517"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1086"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="534"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK95406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1420" mass="159888" checksum="6A129CF644978D6F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMX1</accession>
    <name>X0CMX1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="17">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">FOQG_04091</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 17">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 17">Membrane</location>
            <topology evidence="1 17">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="17"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0206">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000846_5_2_1"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000090">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000172">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF174">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="515"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1291"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1341"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1372"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1403"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1448"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="216"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="19">
        <location>
            <begin position="352"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="21">
        <location>
            <begin position="1227"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="661"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="876"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1499"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="661"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="695"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="712"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="878"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="904"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="944"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="1544"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="14">
        <location>
            <position position="628"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="628"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="628"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="629"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="630"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="630"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="786"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="832"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="855"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1006"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1086"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1087"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1088"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1180"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="1201"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1205"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="1205"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EXK95526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1556" mass="176400" checksum="1127893E0EE6C0FF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN10</accession>
    <name>X0CN10_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_11889</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN10"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07106">
        <property type="entry name" value="ALDH_AldA-AAD23400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044086">
        <property type="entry name" value="LUC3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK83937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="477" mass="51813" checksum="D20256C706EC8BE8" modified="2014-05-14" version="1">MEHFTTFVNTVNGTSVTGKVTQGTDPSTRKKLWDVPVASSEDIENAVSSAKSAFTQWSKTSWSDRQNALLDARDVLIYHKPALAQLITKEGGKPIQFATLEVEHSINFLQFNANQEPLQEQVIQDDDELRLTIREKPLGVIAAICPWNYPLVLSIAKVAAALITGNTIIVKPSPFTPYSILKVVELLQGVFPAGVLQALNGDDKLGPALCQHPGVDKITFTGSTATGKKIAQVAGNLLKPVTLELGGNSASIVCPDVDPKIVAPQVALGSFMNSGQLCVASKRVFVHEDIYDEFLETMVNTVKEWKVAPTSSLEPGIMLGPIQNEMQYNIVKGFFEDSIDNGHCFALGSKPDDSGDAFVIKPAIIDNPPDDSLVVTHEAFGPIVPLMKWKTEDEVIKRANNTLSGLGGAVWSKDVDHAQRLADRIEAGTIWINSFEKPLPQAHLAGHKESGVGGEWGRRGLSVYCQPQVIHCYKSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNK8</accession>
    <name>X0CNK8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNK8"/>
    <dbReference type="eggNOG" id="ENOG502SUJQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047454_1_0_1"/>
    <dbReference type="OrthoDB" id="5359669at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="282" mass="31160" checksum="848D182717EB7793" modified="2014-05-14" version="1">MSYFSSQFSSSPVLTMSPQHAHQSMGMASFGHHTPPRFAPMPSQFAAQPVRPSAAGRKRSRDEASENLEPDMKSLPVEEPEEEWIYGPGMTLIKKSTRYVTDASSQSGTWVEEKKAAEEAAMKEARSLIRNPKLQRVSPTLSSAPAASTSPLQSEVKPATEGPIVDNFTLHLGIGWRRISEEEHIQAAARGWARYIENHFPVSNARILLESNGLQSYLVETNEGFFLFAENLRQGQLVSQTAEGALRNLRCSPPIFDGMEVLSAAESPRPTNAVPDMDMRMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPV3</accession>
    <name>X0CPV3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Prostaglandin-endoperoxide synthase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_05470</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPV3"/>
    <dbReference type="eggNOG" id="KOG2408">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002329_1_0_1"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20612">
        <property type="entry name" value="CYP_LDS-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09817">
        <property type="entry name" value="linoleate_diol_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034812">
        <property type="entry name" value="Ppo-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF13">
        <property type="entry name" value="LINOLEATE 10R-LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK93343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1101" mass="123684" checksum="5B32AB0807E97B0F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPW3</accession>
    <name>X0CPW3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">4-hydroxybenzoate polyprenyltransferase, mitochondrial</fullName>
            <shortName evidence="11">4-HB polyprenyltransferase</shortName>
            <ecNumber evidence="11">2.5.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Para-hydroxybenzoate--polyprenyltransferase</fullName>
            <shortName evidence="11">PHB:PPT</shortName>
            <shortName evidence="11">PHB:polyprenyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_05150</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>an all-trans-polyprenyl diphosphate + 4-hydroxybenzoate = a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:44504"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="2.5.1.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Mitochondrion inner membrane</location>
            <topology evidence="2 11">Multi-pass membrane protein</topology>
            <orientation evidence="2 11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.39" evidence="11"/>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPW3"/>
    <dbReference type="eggNOG" id="KOG1381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034879_2_0_1"/>
    <dbReference type="OrthoDB" id="18170at2759"/>
    <dbReference type="UniPathway" id="UPA00213"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate polyprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1780:FF:000001">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.140:FF:000003">
        <property type="entry name" value="4-hydroxybenzoate polyprenyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01635">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006370">
        <property type="entry name" value="HB_polyprenyltransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01474">
        <property type="entry name" value="ubiA_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00058997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK92889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="405" mass="43768" checksum="46A318440D001079" modified="2014-05-14" version="1">MRLSALPRASAWAQCRGISGQALKVPRQLQTRPSLIRACQGLRQPWHRNQRAVGFHEAKPRSLPLVTQDLDSPSAPTAPAPYKPPETGLLSKLPASWVPYAELIRLDKPAGTYYLFFPCLFSTLMAAPMAMPMATPGSVIGTSLLFFSGALIMRGAGCTINDLWDRNLDPHVSRTRLRPIARGAITPFKGLVYTGVQLFAGLGILLQFPLPCLFYGVPSLLLVASYPLAKRVTYYPQAVLGLTFSWGAIMGFPALGIDLLSHTPALTAAACLYASNIAWTILYDMIYAHMDIKDDVKAGIKSIALKHDAETKQVLTGLAAVQISLLAAAGFAAGAGPAFFVGSCGGAMVTLGIMIKRVNLKDVKDCWWWFINGCWITGGVISLGLAADYTIRYVQGPQDEVKSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQL0</accession>
    <name>X0CQL0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pectate lyase</fullName>
            <ecNumber evidence="10">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_11032</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="10"/>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQL0"/>
    <dbReference type="eggNOG" id="ENOG502RYK9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044863_1_0_1"/>
    <dbReference type="OrthoDB" id="441042at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025093582" description="Pectate lyase" evidence="10">
        <location>
            <begin position="18"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="233"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK84787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="367" mass="37377" checksum="299B228DC9248582" modified="2014-05-14" version="1">MQYRVIMAATLAIGAYAAPAPLITGAPSLSRRQDSESGSGGSGGSSVLDAPMTIAAGESFDGGNAIFDRGVSCTGQVEGGDSDAVFILEKGATLSNVRIGPNQIEGVHCNGGCTLNNVVWDAVCEDAFSIKKQEDGETTTINGGGATGAEDKVIQHNGGGTVIIKDFEVSDFGKLYRSCGNCKEMPARHVEISGGSASNGKILVGINPNMGDTAKISGIQLTNVPKECITFEGVTDGSEPKEVGTCDSNAGSGSGSGSGDSTEAPATPTTPADGSETPAASEVADPVETSADGSQGDDQSGDDQPGDNDDGDNDESDDDKKDDDSDDENKDEQSDNENQDQESESDNQQAQPSQPNFSFGSGGFGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQM5</accession>
    <name>X0CQM5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQM5"/>
    <dbReference type="HOGENOM" id="CLU_1540097_0_0_1"/>
    <dbReference type="OrthoDB" id="4973424at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="174" mass="19956" checksum="7F24699D944AF66F" modified="2014-05-14" version="1">MPSNQDSTEPWDCISRISEDTPSLSSSWQDLGERPEEPESQTAETEGNQQSHEADTDSDVGGVRGPQVQSNHIQNPFRVCGVQVILCLCERSFEEQRPPKDYHIIRLNPELRLAADLFMNGRFGDEQLEKTIHYFRSLRQSLERFIRNPSYDSVSFYCCMAAIERRGESVARGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRZ1</accession>
    <name>X0CRZ1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRZ1"/>
    <dbReference type="HOGENOM" id="CLU_2722348_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="72" mass="8023" checksum="6F9F7272B79828FE" modified="2014-05-14" version="1">MKDRRPRYGKFRGEVKNCERDWSFKLSEAVVKDGVVRIKGQETTAKSSTAMTCTKARVQTSISGQSSPALDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSY2</accession>
    <name>X0CSY2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02499</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSY2"/>
    <dbReference type="eggNOG" id="ENOG502S5J2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063111_1_0_1"/>
    <dbReference type="OrthoDB" id="5284712at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451">
        <property type="entry name" value="MARVEL DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF3">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK97231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="30625" checksum="99AABFC2EFF8153E" modified="2014-05-14" version="1">MRFEIDPDIVPNLKLGLHSFQIIISLVAWCLQIGVFNAKDAEVTGRNGWTFAVCFLSVPAWIFLIMTPRWGRTRRFAQPHAMLAVDAAFTIIWLSAFATQAAYNAAGQCGTACSISKGIVGCGVLVTLLFAGSTFVSAFTLNYYNNHNILPGYDNRQMGSDNIDPDKAAFSMAPHGDEAYERVDMDDHEPSGSAYGGGYNNNSYNSHSRYGDANPYSADDEDPDRFGALPPRNNTLFDNDTEYHSGGAPPSMPASYANPTGGHPYEDVPAQFPAGNYDRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CW25</accession>
    <name>X0CW25_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CW25"/>
    <dbReference type="HOGENOM" id="CLU_004498_8_1_1"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001716">
        <property type="term" value="F:L-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF342">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="126"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="351"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="764" mass="86301" checksum="7D6581376C334D88" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWN0</accession>
    <name>X0CWN0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Heat shock 70 kDa protein 12A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01446</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWN0"/>
    <dbReference type="eggNOG" id="KOG0101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009958_6_2_1"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF79">
        <property type="entry name" value="HSP70 FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK98576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="747" mass="81706" checksum="28CB36357F7DFF77" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXG0</accession>
    <name>X0CXG0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01603</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXG0"/>
    <dbReference type="eggNOG" id="KOG0151">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007957_0_0_1"/>
    <dbReference type="OrthoDB" id="377209at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051485">
        <property type="entry name" value="SR-CTD_assoc_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140">
        <property type="entry name" value="RNA PROCESSING PROTEIN LD23810P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140:SF0">
        <property type="entry name" value="U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CID" evidence="3">
        <location>
            <begin position="461"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="273"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="521"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="673"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="679"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="780"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK98851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="789" mass="86586" checksum="20C34A0B77CEE813" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYN0</accession>
    <name>X0CYN0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cupin 2 conserved barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01819</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYN0"/>
    <dbReference type="eggNOG" id="ENOG502SRGT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158082_0_0_1"/>
    <dbReference type="OrthoDB" id="5270965at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40434:SF1">
        <property type="entry name" value="CUPIN TYPE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40434">
        <property type="entry name" value="CUPIN_2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="10307" checksum="CA09DA905DD684A2" modified="2014-05-14" version="1">MGFGNEYEEQVRAWGFERVFTWSDSPNTHYPPHSHAALTTHLIIEGSITIWYPQEKDSQKQVYGIGSRIDVDAGRIHEVQVGGSGCTMVIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYN5</accession>
    <name>X0CYN5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">tRNA(His) guanylyltransferase</fullName>
            <ecNumber evidence="3 14">2.7.7.79</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">tRNA-histidine guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">FOQG_03180</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a 5'-end ribonucleotide-tRNA(His) + GTP + ATP + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54564"/>
            <dbReference type="Rhea" id="RHEA-COMP:14193"/>
            <dbReference type="Rhea" id="RHEA-COMP:14917"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:141847"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.7.79"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="16">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the tRNA(His) guanylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.79" evidence="3 14"/>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYN5"/>
    <dbReference type="HOGENOM" id="CLU_044271_1_1_1"/>
    <dbReference type="OrthoDB" id="62560at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008193">
        <property type="term" value="F:tRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3000:FF:000001">
        <property type="entry name" value="tRNA(His) guanylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025845">
        <property type="entry name" value="Thg1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024956">
        <property type="entry name" value="tRNAHis_GuaTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007537">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038469">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729:SF6">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04446">
        <property type="entry name" value="Thg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14413">
        <property type="entry name" value="Thg1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028980">
        <property type="entry name" value="tRNAHis_guanylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 14 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 14 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14 21" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <keyword evidence="5 14 21" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0819">tRNA processing</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936701" description="tRNA(His) guanylyltransferase" evidence="18">
        <location>
            <begin position="33"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="tRNAHis guanylyltransferase catalytic" evidence="19">
        <location>
            <begin position="29"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Thg1 C-terminal" evidence="20">
        <location>
            <begin position="133"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="219"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="69"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR028980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR028980-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR028980-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF14413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EXK95974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="282" mass="32556" checksum="10DE8C9063B3F87F" modified="2014-05-14" version="1">MDRGASRWKRVHKVQLNFSLLMSLLTIDRMCAKYGFEKPNDRRALDLMNTAAKAVVTELPEITIAYGVSDEYSFVFHKACTLFDRRASKLVSTVVSTFTANYVYFWSTHFPDSPLSPPLPSFDGRAVCYPSVQNLRDYMSWRQADCHINNLYNTCFWSLIQLGGLDNKEAESTLARTLAADKNEILFSRFSINYNNEPEIYRKGSVIFRDYELVDPNSHNTMQTIDSQAEPVEQSKSQKEKDKKSRAKARVVVEHMDIIKDDFWNQRPWLLSNKPGKIPKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYR8</accession>
    <name>X0CYR8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYR8"/>
    <dbReference type="eggNOG" id="ENOG502T4ZD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1855373_0_0_1"/>
    <dbReference type="OrthoDB" id="5038898at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="138" mass="15894" checksum="FD53C3FCC3F8F014" modified="2014-05-14" version="1">MADPGFLVPDLIEEASKLSIDDLDTDKSASTISRYQEFPYAHFHSSKTKPDPDGMNKTSPEYQEGVRKAIKALEEKYLEVYQDYQASKNDLILLIEEHEEYSWNEFILDPSRVHALWRRGNWRASTLSLAFAISTMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZE7</accession>
    <name>X0CZE7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZE7"/>
    <dbReference type="HOGENOM" id="CLU_008751_2_0_1"/>
    <dbReference type="OrthoDB" id="1577640at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1074" mass="121508" checksum="F415EACF4A817403" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0F2</accession>
    <name>X0D0F2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C-CAP/cofactor C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_02380</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBCC family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0F2"/>
    <dbReference type="eggNOG" id="KOG2512">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="194775at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.70:FF:000011">
        <property type="entry name" value="Tubulin-specific chaperone c, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1250">
        <property type="entry name" value="Tubulin Binding Cofactor C, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027684">
        <property type="entry name" value="TBCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031925">
        <property type="entry name" value="TBCC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038397">
        <property type="entry name" value="TBCC_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139">
        <property type="entry name" value="TUBULIN FOLDING COFACTOR C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16752">
        <property type="entry name" value="TBCC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="8">
        <location>
            <begin position="188"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK97038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="390" mass="43020" checksum="A3D4C2B9D854B3C5" modified="2014-05-14" version="1">METQVQTATHQHDPWAATHQVILQSATMDPKQRFYNHFLESVTVLRDLIDELPSIASVGGERQEAIDHILASIAKLQNEVSDAADYTPSYDRKQYSETIKTLQDKLNETITKITPKSKFQFRRKTDHVDMGAPENDPRLSPGSHSRAKHDTAIASTIASPPSVRKEDTLSELPSKDTYKNYNEEMARPSASSLRKPSFSAAKNISISNHSGLHIILPSSASRATSSGSLTDLKNCIIDMSIPTSSGSAFPGLAIKNVSKSLIVGGRVNGAVHITGVSDSTIVVVARQVRIHECSNVDIYLHCGSHPIIEDCSGMRFSPLPKAYMTDAEEPEENQWDQVDDFKWLKAGHSPNWTTLSENERLSDDLWRSVVPGQPGVSVEESLKKLGIPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0Y5</accession>
    <name>X0D0Y5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Formate dehydrogenase</fullName>
            <shortName evidence="6">FDH</shortName>
            <ecNumber evidence="2 6">1.17.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">NAD-dependent formate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_02458</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>formate + NAD(+) = CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:15985"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.9" evidence="2 6"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0Y5"/>
    <dbReference type="eggNOG" id="KOG0069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_0_0_1"/>
    <dbReference type="OrthoDB" id="418179at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042183">
        <property type="term" value="P:formate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05302">
        <property type="entry name" value="FDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000057">
        <property type="entry name" value="Formate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03210">
        <property type="entry name" value="Formate_dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033689">
        <property type="entry name" value="FDH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005750">
        <property type="entry name" value="PRK07574.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938">
        <property type="entry name" value="FORMATE DEHYDROGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938:SF9">
        <property type="entry name" value="FORMATE DEHYDROGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="8">
        <location>
            <begin position="34"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="9">
        <location>
            <begin position="129"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="175"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="231"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="312"/>
            <end position="315"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="6">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="6">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00071864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK97178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="365" mass="40041" checksum="0C2D0762E6A76985" modified="2014-05-14" version="1">MVKVLAVLYDGGQHAKDQPLLLGTTENELGIRKWLEDQGHTLITTSDKDDEGSTFDKELEDAEIIITTPFHPGYLTAERLARAKKLKLAVTAGIGSDHVDLNAANKTNGGITVAEVTGSNVVSVAEHVLMTILVLVRNFVPAHEQIEAGDWNVAHAAKQEFDLEGKVVGTVAVGRIGERVLRRLKPFDCKELLYFDYQPLSPEKEKEIGCRRVDTLEEMLAQCDIVTINCPLHEKTKGLFNKDLIAKMKKGSYLVNTARGAIVVKEDVAAALKSGHLAGYGGDVWDHQPAPKDHPLRTAKNNWGGGNAMVPHMSGTSLDAQIRYANGTKAIIDSYLSGRHDYKPEDLIVHQGDYATKAYGQREKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0Z9</accession>
    <name>X0D0Z9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rRNA-processing protein EFG1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">rRNA-processing protein efg1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_00638</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in rRNA processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EFG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0Z9"/>
    <dbReference type="eggNOG" id="KOG4484">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066912_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019310">
        <property type="entry name" value="Efg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050786">
        <property type="entry name" value="EFG1_rRNA-proc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33911">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33911:SF1">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10153">
        <property type="entry name" value="Efg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="208"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="104"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="256"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXL00466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="303" mass="34887" checksum="D02DFBBC6248238D" modified="2014-05-14" version="1">MGQKREYSEIGSPEPRNRPSFNGAKKHKSSKSKHRPNEGTSTWAKKRTRTIERLLNRNQELPANVRNDLERELGALKATVSDKSFQKLRSAMISKYHMVRFFERKKASRLAKQLRKKIEETESTETDEIEALKRDLHVAEVDEAYTQHFPHAEPYISLYTSAKSEKEEEDKDDDKLDYTPLKHRGLLHTERPPIWSDIEQAMKGGPHALRNLRERRPTELTQEAQSERRQKKPKATTTNGALKAQPKPQATKEKPAPFAKVKGKAAAAPKNRRERRLQERQAAQPVVKSDDDDSDEGGFFEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1L8</accession>
    <name>X0D1L8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1L8"/>
    <dbReference type="HOGENOM" id="CLU_3368493_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="35" mass="4170" checksum="D9514F45A419FD5B" modified="2014-05-14" version="1">MERNWVGGRSGKTRTKMQKAKKKQSRGFKGWSYCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1T7</accession>
    <name>X0D1T7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3',5'-cyclic-nucleotide phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1T7"/>
    <dbReference type="eggNOG" id="ENOG502RFKK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016658_1_0_1"/>
    <dbReference type="OrthoDB" id="258495at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004115">
        <property type="term" value="F:3',5'-cyclic-AMP phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047555">
        <property type="term" value="F:3',5'-cyclic-GMP phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006198">
        <property type="term" value="P:cAMP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902660">
        <property type="term" value="P:negative regulation of glucose mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07735">
        <property type="entry name" value="class_II_PDE_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000396">
        <property type="entry name" value="Pdiesterase2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28283">
        <property type="entry name" value="3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28283:SF1">
        <property type="entry name" value="3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02112">
        <property type="entry name" value="PDEase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00388">
        <property type="entry name" value="PDIESTERASE2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="504" mass="54939" checksum="A93483064FC1CB78" modified="2014-05-14" version="1">MGAEVEPALQVIVLGSGGGPQESNTTAFLVRSVAQKWHRGSIIAVDAGVHLSAITRIMEESIPSPPPPPPFTLTIGPFAGLELPYSSPSANASHITRSLVDTYLITHPHLDHISGFVVNTAGFPGTRPKKLAALPSTIQAFKNHIFNNVIWPNLSDENNGAGLVTYMRLVEGGSPTLGDGESRGYIEVADGLLIKVWSVSHGHCLEKHSHRGSTSSASTRFSSHDASMPQGPIARSASYYPGSISLHRGSLMIPQNSFSPVTTTLEQEQICVYNSSAYFIQDPTTHREVLIFGDVEPDSISLSPRNLNIWQQAAPKIASGNLKAIFIECSYDESQAEDRLYGHLKPRYVIEELRALAHEVEVERKSHYSEPKKRKRMGSTTDETPRRNPSIANLTSEDPVSPRTIKASTPDYVHPGIETPPTPHLASPTAELTLNPSDSFTSVPRIKRPLEGLKVVIIHVKDRLDDGPNVGNTILKQLHNFESETESPLGCEFIISHSGQSIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0D222</accession>
    <name>X0D222_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D222"/>
    <dbReference type="eggNOG" id="ENOG502RF9B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045142_0_0_1"/>
    <dbReference type="OrthoDB" id="5234702at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="342" mass="38851" checksum="239DAAA855E06659" modified="2014-05-14" version="1">MAAMMSSVNPFTPVTPPPESHSFPKLPAQRPLQNNLKRKASMQEPFSGLAGLNTPTMMAPPPPPTSQPRMSSSPNRSSGPSSSNTPQPSESTTPELPSIAGANLDPKYLAMVSRIAAYYQQRCQAVANYQQQRCQAWANMHRQKCQDMMQASMLVVAWYVRDRIQRRRRREKRHFRSGLRRRTDQNKIARTEVVRRWVKQIPEGPESPNEPINVQIADREEAEFSMDRETQPDKDTKLFEMADNLIKSQYKKIEVPIMGVLNFDESDNDSESDLDEPEPEQYDEMDEAEDLAEDDEYYEVEDDELYDDEDEIEYTGDGASEVVHHGTGTGSGSRNNNLSETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2B3</accession>
    <name>X0D2B3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_02789</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2B3"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_376861_0_0_1"/>
    <dbReference type="OrthoDB" id="2428527at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF1">
        <property type="entry name" value="LOW AFFINITY AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="567"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="605"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="637"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="662"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="702"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="741"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="301"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="178"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK97673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="768" mass="83149" checksum="F3B6CC32982D7F86" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3K8</accession>
    <name>X0D3K8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Life-span regulatory factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3K8"/>
    <dbReference type="eggNOG" id="ENOG502R8KJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1111612_0_0_1"/>
    <dbReference type="OrthoDB" id="3599883at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024368">
        <property type="entry name" value="Ecl1/2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12855">
        <property type="entry name" value="Ecl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL01012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="28828" checksum="B0ACD89D2FB84ABF" modified="2014-05-14" version="1">MHHSRKKSGHGLPNSSATDVRKAVTATDPAKYKRPVMTRRHTPQKLGRSQREREREWTESWEDERESFPQFCMTCEKQFIPHDDMFLYCSDNCRRVDQTTSSQPSSSVCHYASSNYPFHSAGNPEPKDIIPRASPSRPSSMILSSPPATPGTGAPNFQHTSAISALRSLNVRPPSPPSPTGSSSNLWPFSRSAATSPYSSYSRPSAPYLSSTYDGGYYGAGGSGYNYEATSGGMDRPLPSRHPSTYSRPRSIELVTPMVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3Q4</accession>
    <name>X0D3Q4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle subunit SRP14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Signal recognition particle 14 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_02819</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of a fungal signal recognition particle (SRP) complex that consists of a 7SL RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SRP14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3Q4"/>
    <dbReference type="eggNOG" id="ENOG502S9PU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094309_1_0_1"/>
    <dbReference type="OrthoDB" id="19209at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.10">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, srp9/1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003210">
        <property type="entry name" value="Signal_recog_particle_SRP14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009018">
        <property type="entry name" value="Signal_recog_particle_SRP9/14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12013">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02290">
        <property type="entry name" value="SRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54762">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, SRP9/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK97749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="154" mass="16997" checksum="5A832311BAD92019" modified="2014-05-14" version="1">MSTSILVGQHSSLNIHRLLTVSYPITMADSHMSHDEFFAKLGELFNHRKGSDHGAIYLSQKRLTYGQGIPSPSEEEPSPDIHPGKPLPLIIRATNGKGKKDRSNKAKLSTVVNPEDLEAFYVRYADVCKAGMTALKPRDRSKKKAKAKKKKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5M9</accession>
    <name>X0D5M9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5M9"/>
    <dbReference type="HOGENOM" id="CLU_131085_0_0_1"/>
    <dbReference type="OrthoDB" id="5418749at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42030">
        <property type="entry name" value="DRBM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42030:SF1">
        <property type="entry name" value="DRBM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10564" checksum="277135AE9949CDCD" modified="2014-05-14" version="1">MEVQSATPTGPWQDQLDNVCRDAQLRPPVFQIVSDRRGGRTAWSSRVTVHGKTLAARFWYDGKNLNNAREDAAECAVKWLTGSESSSPTQQWGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6F5</accession>
    <name>X0D6F5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-specific glutamate dehydrogenase</fullName>
            <ecNumber evidence="4">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_07068</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6F5"/>
    <dbReference type="OrthoDB" id="184415at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056365">
        <property type="entry name" value="NAD-GDH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016210">
        <property type="entry name" value="NAD-GDH_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055480">
        <property type="entry name" value="NAD-GDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF24">
        <property type="entry name" value="NAD-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23147">
        <property type="entry name" value="GDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23152">
        <property type="entry name" value="GDH_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000184">
        <property type="entry name" value="GDH_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="713"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK90212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1078" mass="120981" checksum="EFD79547F5A72871" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6N4</accession>
    <name>X0D6N4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA mismatch repair protein HSM3 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6N4"/>
    <dbReference type="eggNOG" id="ENOG502S03U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064433_0_0_1"/>
    <dbReference type="OrthoDB" id="4538483at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041335">
        <property type="entry name" value="HSM3_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18795">
        <property type="entry name" value="HSM3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein HSM3 N-terminal" evidence="1">
        <location>
            <begin position="24"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="369" mass="40282" checksum="3546BBDD8403B4A5" modified="2014-05-14" version="1">MSERVVPQNSDGAPVTGLAELLSHLTELHEPGNESAPLNNKLFDDVELQLTPSNIPIIQPTLLPPLMSLLKTTTQDPTSLSVVFSLTTKLLSPFSFTQCLSLGGAESLVSALQSPLPGANLLALNIIQKAASSPAEVDSLASLPEVVEELLRIWLSSPDADVGGRSTRVLGSLLETDCDIIPDTTMSNGVNGASPAETQLIKRRIPGHASLWRLVIWDRHYLELIVSLCRPAIINRQATFAQDRLLRLIPRLTALHPRAMAISPFPDLFPLPEYADESIGHGLLQWAALSMVDTSDVLMHQTLIVFYESFVSIMRIAGDSADKDAIVRNVVKAATSQDQELKQALRTLPDRTIQEEAEPLARYISRILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7X0</accession>
    <name>X0D7X0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Transcription factor Pig1p</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_01815</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7X0"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="177"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK99229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="914" mass="100860" checksum="DDA9587316B0C72D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8Q5</accession>
    <name>X0D8Q5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_00017</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8Q5"/>
    <dbReference type="eggNOG" id="ENOG502S1DJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_5_0_1"/>
    <dbReference type="OrthoDB" id="4570620at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097237">
        <property type="term" value="P:cellular response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050097">
        <property type="entry name" value="Ferredoxin-NADP_redctase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48105">
        <property type="entry name" value="THIOREDOXIN REDUCTASE 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938243" description="FAD/NAD(P)-binding domain-containing protein" evidence="4">
        <location>
            <begin position="25"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="32"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK99534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="387" mass="42913" checksum="791EDA3E18EFAAE9" modified="2014-05-14" version="1">MSVLYISTMLFPLLALLSLTNVIAIAPPQPDYDAIVIGGGPAGLSALSGLARVRRHVLLIDSGEYRNGPTTHMHDVIGWDGVQPAYFRYESRRILSHYKTVKMENGTVTNINPLPGANTRFSVSVDYPDQHRTTKITARKIVLATGLKDILPSTPGIAENWGRGIYSCPWCDGHEYADQPLGLLCPLDKIASHVLNVLSLTTDIVAFVNGTDNDETRRVADEQFPQWEEYLKLHNVTIDNRTITSLERLKDGEEVNKEPWLPSVPKDDLFGVHFTEGEGEPVQRVAFLSSVPNKQRSDIGERAGVELTNGKLRVTDNHTMLTNVPGIYAVGDANSDSAENVPHAMFTGKRAAMFLHATLEREKRDAELAGRLKRDVYLEESSWPENC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0DAW3</accession>
    <name>X0DAW3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycoprotease family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DAW3"/>
    <dbReference type="eggNOG" id="ENOG502SB2Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004045_0_0_1"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="597"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXL00669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1005" mass="110899" checksum="E57D9F194C10B81E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0DB56</accession>
    <name>X0DB56_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMMECR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DB56"/>
    <dbReference type="eggNOG" id="KOG3274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052828_2_1_1"/>
    <dbReference type="OrthoDB" id="24630at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="entry name" value="Hypothetical protein ph0010, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00296">
        <property type="entry name" value="TIGR00296 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016:SF0">
        <property type="entry name" value="AMME SYNDROME CANDIDATE GENE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="AMMECR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="AMMECR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="2">
        <location>
            <begin position="51"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXL00370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="249" mass="27683" checksum="58FDB82F00695744" modified="2014-05-14" version="1">MATRDHCLLCFEALEAHLTHRKALTLEEIQEYSASASDSEPVAPKTLDDPSLRHLAIPDASASSSSSSTSLGASTPATSTSSLPIPPTSAPLFVTWNTMEDGEPVLRGCIGTFEAQDLAEGIPEYALISALQDTRFSPIRKSELPTLQVAVTLLTDFEEVDDIFNWEIGVHGIRLSFYDRGRRYGSTYLPDVASEQGWTKEETLFSLIRKAGWTGSRGRWKDLDLKVTRYQGKKTTLEYADYKKWIDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0DND7</accession>
    <name>X0DND7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03114</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DND7"/>
    <dbReference type="eggNOG" id="ENOG502SCT5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135723_1_2_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_bL36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_bL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_bL36_sp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052010">
        <property type="entry name" value="Ribosomal_LSU_bL36"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18804">
        <property type="entry name" value="RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18804:SF16">
        <property type="entry name" value="RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="Ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK95852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="99" mass="11047" checksum="2589804E9A5EF216" modified="2014-05-14" version="1">MASFLRAFSLSVRSLTPSNAMGAFATRANWSLFASPSTTPISRALGNGLMQQTRGMKVHSSVKKRCEHCKVVRRKAGKRHNGYLYIICKANPRHKQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0DT29</accession>
    <name>X0DT29_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_02620</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DT29"/>
    <dbReference type="eggNOG" id="KOG4463">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057574_0_0_1"/>
    <dbReference type="OrthoDB" id="272778at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013861">
        <property type="entry name" value="TMEM115/Pdh1/Rbl19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF21">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08551">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01160">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK97417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="30784" checksum="3781058BDA1DC5F8" modified="2014-05-14" version="1">MSFTNTPVTRLGVVGLVAGSIIASVLDVKHYFYILIDTHIWRYRQFWRILAYQLCYVNSTEVLFAAMSLYNLRIVERMWGSRKFASFLTVTFFITSIIPPVVSMVLRPLAAGWFNYIPAGPTPIIFAILAQYHAMVPHMYKYRVATSEAPPTDRPFVGLTFSDKSYKYAIALHLALLQWPGSVLGAVTGWIVGYSWREGLLPAALVRWRVPGWVVGLSSHRRSAEFEGLRRRLEDENSTTSVATGAQASTEGQAERRRTMGQQIMDQVREVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0E1N6</accession>
    <name>X0E1N6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit OST2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_00479</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DAD/OST2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E1N6"/>
    <dbReference type="eggNOG" id="KOG1746">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111220_0_0_1"/>
    <dbReference type="OrthoDB" id="445566at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003038">
        <property type="entry name" value="DAD/Ost2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02109">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXL00218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="158" mass="17208" checksum="B45CC9AD06CB47CE" modified="2014-05-14" version="1">MAAKKNVRDITPSAAATTQASTTSAGSVPPQPQPKPVAIAKNEIKGEVQWDKVVQNLYNHYVNNTPQRIKLVDAFMVFLVVVGVLQFINCALAGTFPFNAFLSGFCVTVGQFVLTASLRLQTNEAVKNDCPSVSPERAFADYIVCSLILHFFAINFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0E4S5</accession>
    <name>X0E4S5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 19">ATP-dependent DNA helicase II subunit 2</fullName>
            <ecNumber evidence="4 19">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">FOQG_01041</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 19">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the ku80 family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4 19"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E4S5"/>
    <dbReference type="eggNOG" id="KOG2326">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="30826at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043564">
        <property type="term" value="C:Ku70:Ku80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00873">
        <property type="entry name" value="KU80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.290.10:FF:000008">
        <property type="entry name" value="ATP-dependent DNA helicase II subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000073">
        <property type="entry name" value="ATP-dependent DNA helicase II subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1600.10:FF:000002">
        <property type="entry name" value="X-ray repair cross-complementing protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.240">
        <property type="entry name" value="Ku, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="DNA_bd_Ku70/Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024193">
        <property type="entry name" value="Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036494">
        <property type="entry name" value="Ku_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005161">
        <property type="entry name" value="Ku_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014893">
        <property type="entry name" value="Ku_PK_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604">
        <property type="entry name" value="KU AUTOANTIGEN DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604:SF4">
        <property type="entry name" value="X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03731">
        <property type="entry name" value="Ku_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08785">
        <property type="entry name" value="Ku_PK_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016570">
        <property type="entry name" value="Ku80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101420">
        <property type="entry name" value="C-terminal domain of Ku80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 19" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14 19" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="15 19" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13 19" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 19 21" id="KW-0347">Helicase</keyword>
    <keyword evidence="9 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16 19" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="VWFA" evidence="20">
        <location>
            <begin position="6"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR016570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EXL01233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="716" mass="79490" checksum="6E3CB5DCA2D4CC35" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1T6</accession>
    <name>X0B1T6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658768">
        <property type="protein sequence ID" value="EXK76090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1T6"/>
    <dbReference type="HOGENOM" id="CLU_711816_0_0_1"/>
    <dbReference type="OrthoDB" id="5106185at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936105" evidence="2">
        <location>
            <begin position="20"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="373" mass="42043" checksum="B185A462A951D752" modified="2014-05-14" version="1">MKLHQVTAILAFVAAGVLATPDGYADRGNNNHPAKNGDHGDGGKPNRDGSGYYPHPGSDRGYHGSKSGHGDYNDNHADSGGRDHDKDRGKDRGKDYDKDHDKDRGKDRTDRGKDRGKDYDKDHGDHHGKYPGNRGGKDGHGEKGWGDKCKKYNWDYSKATYSASFNKYKKCPAGDSYKVSGKIAPCDGHGYYGRDEQCLFVTYDDWDKWSAKTAYLGIYATEEKGFKEKKKLNFNKYCKKNKCVVPVKKIPGYPGFKDSVWIGYDDDQCKQQYWGGYGHGGKKNDHGDHEGKHDDDKDSYDNDYDEKKDRRGDKDNNYGEDADNYDSDDNGYGSGHGDYRGSSGYGSRYGRRSSVKYVEVDVHVKYAKKCHKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3N3</accession>
    <name>X0B3N3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979529">
        <property type="protein sequence ID" value="EXK76356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3N3"/>
    <dbReference type="HOGENOM" id="CLU_1917179_0_0_1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="14503" checksum="DBC495E70ACDC6C8" modified="2014-05-14" version="1">MASINVGILVYDYQAIDVVGPVDLLHSANSGFLEVSKVFGPIDDDAISRAPNFIFHHVGITKEPFHLFTSAITLTPTTTVDECPELDIILLGGPNPVGFELHQNSTCLYGSSRWKERNYQPRRVSMGQGELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5H1</accession>
    <name>X0B5H1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658616">
        <property type="protein sequence ID" value="EXK77365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5H1"/>
    <dbReference type="HOGENOM" id="CLU_1896322_0_0_1"/>
    <dbReference type="OrthoDB" id="5104403at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="134" mass="14900" checksum="5CBF0A45283315C7" modified="2014-05-14" version="1">MYFDVQPEPHEAHGSTPELGQRESEHPLLIQPTPPSSNKVSRSGSQVQSQPQPGISDEEERKLPPGLEVISTSSHRSEEQPDEPLGIFEPRPLTALAKATQEKCKRPVQRDYVTAAEKIEAPPWISPLKLGHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7M0</accession>
    <name>X0B7M0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658578">
        <property type="protein sequence ID" value="EXK77746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7M0"/>
    <dbReference type="HOGENOM" id="CLU_2606154_0_0_1"/>
    <dbReference type="OrthoDB" id="5020773at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="79" mass="8787" checksum="81D7E1907647CA59" modified="2014-05-14" version="1">MIPTGYTASTPVHAAALLLDPSKRRNYIERNWQESWHAPAIATTQQIWLGEYNAAPIPESLRVPLDVSSSSGRQRNELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9E4</accession>
    <name>X0B9E4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mitogen-activated protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_16946</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="1"/>
    <dbReference type="EMBL" id="KI979361">
        <property type="protein sequence ID" value="EXK78381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9E4"/>
    <dbReference type="HOGENOM" id="CLU_036828_0_0_1"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="274"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="87"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK78381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="577" mass="64868" checksum="56B39957270D36F2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAE0</accession>
    <name>X0BAE0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658481">
        <property type="protein sequence ID" value="EXK79130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAE0"/>
    <dbReference type="eggNOG" id="ENOG502SV8M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_973470_0_0_1"/>
    <dbReference type="OrthoDB" id="4270785at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="22"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="160"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="287" mass="32787" checksum="12C578C545592616" modified="2014-05-14" version="1">MSSSPDLRIGTKSIRNRADLDDYVYHFNANDKAEYTAYYSKDAVFRFSGFPDRTIDEFLSWVDEIHAGMRETLELKRVVFGQDIVVTEMHTQFRGINGYETDNLAGRWGPVWPGNGPLVKMFVWYTLDEDGHIIQLTEDAYLEKEASRDVIRSHEDFKLYLNAFNTNDFDTFPRYYTSDVTIILDGKQTLHGREEATNFFRNARSQVNEDVNVQSIILDKTGIALKSYIKFTAVANIEDILNFGSGVRQGGGYEAHFLIHYELTPEGKIHYITAAQSGAVKIFNPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBJ3</accession>
    <name>X0BBJ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658479">
        <property type="protein sequence ID" value="EXK79151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBJ3"/>
    <dbReference type="HOGENOM" id="CLU_3242177_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="43" mass="5121" checksum="E50D668ED0972DA7" modified="2014-05-14" version="1">MRATFSWGCYRMEVYITFLKNFIYLRRKASLENIASKGLNEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBY2</accession>
    <name>X0BBY2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979537">
        <property type="protein sequence ID" value="EXK76328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBY2"/>
    <dbReference type="HOGENOM" id="CLU_2573991_0_0_1"/>
    <dbReference type="OrthoDB" id="10298639at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="66" mass="7078" checksum="6EB54E69DB78E57C" modified="2014-05-14" version="1" fragment="single">MTSPCANYYGSAKCRNSVLVFGARCDFCLTAGAGMPINNLLPHPSTPSNEYVKPMNKNVRKNNAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC01</accession>
    <name>X0BC01_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658465">
        <property type="protein sequence ID" value="EXK79660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC01"/>
    <dbReference type="HOGENOM" id="CLU_372158_0_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="541"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="747" mass="83494" checksum="4168E0997231377B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF04</accession>
    <name>X0BF04_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_14832</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658438">
        <property type="protein sequence ID" value="EXK80700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF04"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_1_2_1"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938399" description="FAD-binding PCMH-type domain-containing protein" evidence="5">
        <location>
            <begin position="25"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="62"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK80700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="504" mass="54999" checksum="CFB6B3976ADC5567" modified="2014-05-14" version="1">MLFVMLSSTVLSLLLLAACPATTAKKTESGCDSLKHAFSDKTFYPKDAVYELESQDFWSNNEILEPACVFRPTSAKHVAEAVKLMSTGRTSFGLRGGGHMAIAGANNIDGGPLFVMSNLTTLELAKDKKSVWVGPGLDWGQVYRYLGQHKLAVAGGRLSPVGVPGLLLAGGINFHGNQRGWAADNVLEYELVVSSGKIISVTSKSHPDLFWALKGGSNNFGIVTKFKLATFPSDQIYAGIYSVADIPGFLKAVANFSAFNTDPLAHIVPQVIAVDEETTIGGAILFYDSDSNPEPECFRPFFDLPAISNTFERKTLAQFSDETGQLVTPKINDQFIAGTTTGKTYEEILKGIQIVNDGFLDALPDLYKILPAKDRVLISVDWQPLGSLWTKASKKYNPGGNALGLDVEKEGTYIAWAEVVEWSGDEHNDAVFKWVEDTTWAIANATQKAGIYDPFTYMGDAAGFQNIYDGYGKGNKQKLLQISRKYDPSRTFQKYWPGGFKIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BF43</accession>
    <name>X0BF43_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658642">
        <property type="protein sequence ID" value="EXK77099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BF43"/>
    <dbReference type="HOGENOM" id="CLU_3335617_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="38" mass="4154" checksum="8071C077FB547784" modified="2014-05-14" version="1">MQHLSEVVASLESFEFLVPELAMMTAAQGLERLTTICG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFK4</accession>
    <name>X0BFK4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14623</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFK4"/>
    <dbReference type="HOGENOM" id="CLU_063263_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="372" mass="42154" checksum="C9475B8AA8805E54" modified="2014-05-14" version="1">MAMQMFEKWRLPDMLSDVKLALATAMTSETPGPNHEAAIQILKESLRLDEKRNDVQRQLKKLETIVSLEGCLARADQGDRHKELQNYWMGESERIGERYHNDDSIRQAELFMARGKFKSAEKLLKQRLVKCMDEKGPRRISKCQHLIFSSLFLSFGSSLHPEDNHSQVRAVVDQAAAALAAYRELGPYSAPLEFILHVSQALKSLGQNQDGQESNMVYAEALRYLGIGESISERLRRDLCSSSGLESLRQKQLLVASSTHDDIFNHALALTFALGDAEKMWRWTQRAKASALSDLVGSQLDLYTRQRPPTFVVDDQIVKLLEDEARLVRKLESAVSIDKISTSMELERVRSMMEEHPRLGRLLASRAGKTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BG88</accession>
    <name>X0BG88_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CMP-sialic acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_14681</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658435">
        <property type="protein sequence ID" value="EXK80826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BG88"/>
    <dbReference type="eggNOG" id="KOG2234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021753_0_0_1"/>
    <dbReference type="OrthoDB" id="408493at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK80826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="778" mass="87014" checksum="0C58F0D83815A6F3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGC1</accession>
    <name>X0BGC1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-dependent DNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658562">
        <property type="protein sequence ID" value="EXK77898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGC1"/>
    <dbReference type="HOGENOM" id="CLU_001248_0_1_1"/>
    <dbReference type="OrthoDB" id="5103340at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="41228" checksum="6D9B5DD5980E00F4" modified="2014-05-14" version="1">MVNEQLCRLRGSPQDFRGIPTVLFCGDFHQFRPIQERSILLPSTATSWFEQDSFRVKQRRQHDKAYTLWRRFITVVMLNEQIRAAGDPELRGLLTRIRLGIQYQSDIDLLNSQCYQEGRRIPWESGITVATPLNRNRWNLNMEATLAFQRQHQAAMRIFISDHKWKDGQPTEEEAFMILNHGDDSAIPVPAIFMFVPGMPVVVNQNTHQGLKLVNGASYTALEVIVDKASPGYQVSADTTLHFGPPAGILLSAETTRNFHFVGMPARTILLTPMSIKIECQRKHPWQQHDVTRKGLPCTPAFACTDYKVQGRTLSRVALELRGTRTTNIDGEMVPSQYMGIKSYSQSALCQKVLTQPETAPYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGP9</accession>
    <name>X0BGP9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14521</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK80996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGP9"/>
    <dbReference type="HOGENOM" id="CLU_028200_0_2_1"/>
    <dbReference type="OrthoDB" id="10017208at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="37"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK80996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="346" mass="38176" checksum="A6A8094E125B8922" modified="2014-05-14" version="1">MNMTTEEMAAKAGEGRSGIAIGVSVSLMALSAVMVGLRLWCRRERQMLGLDDVTAVVALACVLGCGSSIVAMTHYGLGRHIYTLSPRQIILYLRCFWISIVFYTYALFAIKLTFLIHYYRIMSVSSMRWLYLGALGFIILWGINQGIGVFLFCIPLQSFWDPHVKGQCFLSRPTMWYVSGIVHIVTDFAIIVMPLPIVWKLQLPRSQKIYLTGIFGLGSLTLAIAILRMQWLDPVADMTWWNVTAASWSMAEIVSGITCACLPTFKPLLVGIKNWFPRLNQGDSTICLRDQGSEGFTGTTLAAFEGHGGVGTGPKVPTSISTYGTQTSISAFQGGKKSKRNQTQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH26</accession>
    <name>X0BH26_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_14102</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_35_0_1"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000054">
        <property type="entry name" value="ABC multidrug transporter atrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="509"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="591"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="618"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="648"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="755"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1168"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1200"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1239"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1281"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1308"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1435"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="140"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="833"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK81465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1467" mass="163744" checksum="9562BE241FB8870D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIT3</accession>
    <name>X0BIT3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006477_0_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF1">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE EPSILON SUBUNIT HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="48"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="699"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1038"/>
            <end position="1058"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK82085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1369" mass="153435" checksum="239239BCA789484B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJW7</accession>
    <name>X0BJW7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16607</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658505">
        <property type="protein sequence ID" value="EXK78734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJW7"/>
    <dbReference type="HOGENOM" id="CLU_024934_2_0_1"/>
    <dbReference type="OrthoDB" id="4937900at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="391" mass="44135" checksum="77737F850673E512" modified="2014-05-14" version="1">MTQAEGSRKPRQGHRKSRNGCTTCKKRHIKCDERRPECANCSISERECHYAAPKKAKIGTSPYETELTLLSSFQPASIFADSPTPSTPDLHEIESDDLFTFGHLNLLYHVQEHMKDWMMVTDKLLPLADGYVTTALKTPYLMNQLLALSAMHLRSIDNPMADSYMQTATHLRHRALRGFNKCIDDTSETNSTAQFFFASLLALHYIAETVTGLVDGDFAVSLNCTLNYFRLHRGARVMGERANSSFNNSPVSQWIINASREGLEEPQINSPGCTMLASMLETSELNEDSRRACEEATDALAFVIRKIEGPNSWGVHAMMAWSNLIPWHFLTLLEKQIPEALVILAHYAVLMHRFRAFWCLNDLGQRLVEGISGVLAGYWANWLPKLEDDVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK78</accession>
    <name>X0BK78_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_16074</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979349">
        <property type="protein sequence ID" value="EXK79278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK78"/>
    <dbReference type="HOGENOM" id="CLU_000022_45_2_1"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="108"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK79278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="690" mass="76158" checksum="2D110149CFB16F1A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM03</accession>
    <name>X0BM03_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979343">
        <property type="protein sequence ID" value="EXK79938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM03"/>
    <dbReference type="HOGENOM" id="CLU_2941755_0_0_1"/>
    <dbReference type="OrthoDB" id="5097476at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="60" mass="6268" checksum="8CC62CF2C9614476" modified="2014-05-14" version="1">MSPISEPQQAAQPADAKASQPVQMSQPRTQQPMSHKGAQILEPIADVLVMIQSAMGAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMC4</accession>
    <name>X0BMC4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMC4"/>
    <dbReference type="eggNOG" id="ENOG502SS8Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133933_0_0_1"/>
    <dbReference type="OrthoDB" id="4153862at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936391" evidence="1">
        <location>
            <begin position="19"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="132" mass="13405" checksum="07FEBB96F6FCFC2D" modified="2014-05-14" version="1">MQFSITAIVLGLAAFASAGIVDTEGVRNAPRSAVLVTRQNGQNGGRPVPSGECCVANTSLKQDACTASNGQAGRCVPGGNNCGGRLSCVAQANLQCDANVIERGKDLCRAKAANGLFDGGNIIQNLSQAKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMH8</accession>
    <name>X0BMH8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PD-(D/E)XK nuclease-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979340">
        <property type="protein sequence ID" value="EXK80103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMH8"/>
    <dbReference type="HOGENOM" id="CLU_027219_4_1_1"/>
    <dbReference type="OrthoDB" id="4161186at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046797">
        <property type="entry name" value="PDDEXK_12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20516">
        <property type="entry name" value="PDDEXK_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PD-(D/E)XK nuclease-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="115" mass="13125" checksum="CFF2BCDABCF6D22D" modified="2014-05-14" version="1">MIDYAFLLRPDKALETRITNFVAELPDVQSFNQSTHEPLCKEPTGVLIETKVESKRQGEGKTQLGIWLASWFGRVAKFEGSKKLPFLSVILVVCENWELYSAFNKEDRFEVCGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMQ7</accession>
    <name>X0BMQ7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658462">
        <property type="protein sequence ID" value="EXK79739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMQ7"/>
    <dbReference type="HOGENOM" id="CLU_158779_0_0_1"/>
    <dbReference type="OrthoDB" id="4737923at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="94" mass="9888" checksum="C6128E3AAB3862B6" modified="2014-05-14" version="1">MTTNSFGGALPRFDFPSQPAPAVSRMARIHKALPVVLVAATVAAVALKTTQEARESHTSIPAMLFSRAPAQGLVPRGQGIIGKQNVDLGEKPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNL7</accession>
    <name>X0BNL7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979341">
        <property type="protein sequence ID" value="EXK80064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNL7"/>
    <dbReference type="HOGENOM" id="CLU_019833_2_0_1"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="374" mass="42523" checksum="5B78E65A7CAFC05E" modified="2014-05-14" version="1">MSMTWTTLGKDKAGRRLQEDSARMAQRMGLYGDSGAFSYHQLDLSDGRVEAAVCATAWGSFNFQMVMSMSYHQEPIPKRTPRFRIPGKTLTAAQHDVPSTDATYTAVCQFWLVVFDMNYLYYFERSVSISSAVAIFQRLLGWADALPAGVGRDEHNPDHVLNIHIWFHTAIIDLFRPFEHEFPQPKLPAFAGVNATPKAVISASIEQLKRLVYQYRAHCESSKYSIIWQSGMLYLVNYILRDLSSNESQFYFLLCMRGYQHLARYMPFVSGIVQSLIVMTNRQGGSLTANTQRLLKEVRDESRRSREFFSAYPVDLEMVARDPFSASLEKLTSRFQEEPSGASQREVSESGTLPDGWKGSVEDLTTTLSKFEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNM2</accession>
    <name>X0BNM2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Aquaglyceroporin like protein, other eukaryote</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_11936</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>glycerol(in) = glycerol(out)</text>
            <dbReference type="Rhea" id="RHEA:29675"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNM2"/>
    <dbReference type="HOGENOM" id="CLU_020019_9_0_1"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1080.10:FF:000027">
        <property type="entry name" value="MIP aquaporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK83775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="328" mass="35192" checksum="6FDE2597C7947422" modified="2014-05-14" version="1">MATEITHSEHSLGKTDCPAKGTEAHGTMSMEEYEASPGALPPVTYWVRVRKLLRDPFSEFFGVMILVLFGDGSVAQVVLGEGNKGDWQNINWGWALGVMLGVYCGGVSGAHLNPAITLANCIFRKLPWRKFPAYLVAQVLGAMVGSLIVYGNYKSAIDVFEGGPGIRTVGLKTSSAAIFCTYPAPFLTKAGQFFDEFLGSGILAFCLFALLDDGNIGAGNLTPLGLFFVVYGIGACFGSNTGYAINPARDLGPRLMSYALGYGTEVWTAGNYYFWVPVIAPFLGCVFGAFLYDAFIYTGQSPINAPSMGLGHLFKRTKLKGSNARSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSQ8</accession>
    <name>X0BSQ8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glyoxalase I family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSQ8"/>
    <dbReference type="HOGENOM" id="CLU_098384_0_0_1"/>
    <dbReference type="OrthoDB" id="5371818at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050383">
        <property type="entry name" value="GlyoxalaseI/FosfomycinResist"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21366:SF14">
        <property type="entry name" value="GLYOXALASE DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21366">
        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="21"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="199" mass="22232" checksum="5B2B3C9EF7619B5B" modified="2014-05-14" version="1">MTFPGIPNFDASYPKVMSPEGLAHVVLRTSDLKRMQEFYTTFLGGTVTYGSEVISFITYDEEHHRIALLEVPDTKVKNPLTCGLEHIAFSFGSLSSLLLAYRQRKAKGIHPIWCVNHGPTTSIYYKDPDGNMLETQVDNFDTVYATTQFMTSESFAENPVGTDFDPEELISAIQKGVPESTLKQRKEIGARPMPDLASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BT25</accession>
    <name>X0BT25_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">beta-glucosidase</fullName>
            <ecNumber evidence="9">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_13937</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="9"/>
    <dbReference type="EMBL" id="JH658424">
        <property type="protein sequence ID" value="EXK81644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BT25"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_4_0_1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="10">
        <location>
            <begin position="403"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK81644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="838" mass="91367" checksum="13DB8537E53C3122" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BT65</accession>
    <name>X0BT65_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_10728</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BT65"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF32">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="46"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="479"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK85370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="501" mass="54654" checksum="6A611776A3D94E55" modified="2014-05-14" version="1">MASQHEPQVDSSIIKTGAEESQSPLPTCDWTDKAEVKLRRKIDFTILPMLMLGLFALQLDRGNVGYAMTTSFTEDLGINNDNVNTGNQLMLAAVVIFEIPFNMVLSRIGPALWLIIQILAWGTIATAQAAVHNKSGFYATRFLLGMWEAGYLAAALTILASFYTRKEMAMRATLVYVGNYCSAGVSGLLAGLIFKIPETSGLKKWQWLFIIDGLFTLVVGFVFILIMPRSTTNTLPLAGIKWFDLFTAEERDILAKRVILDDPRKHVKLSGISPKTALHILLTSFPMWGHFGINAISITPKGGLVFYTPTIIKNLGFGASTASFLAAVSNFGVCILAILVSWVSDKTLSRGPLCLLCGVYSLVFSGVQFAVVGSSDVWMKYAILTLLGSGVAVSQSLNDAWFSINTEDPQVRCIGLALAVAGSNVGGLAGQNIFVKSDAPYYPNGFLKILCLYAASIVLVAGMIFYYWNDNRRMEKSGELEDATETEGSGGVKRRRVRNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW91</accession>
    <name>X0BW91_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW91"/>
    <dbReference type="HOGENOM" id="CLU_2158527_0_0_1"/>
    <dbReference type="OrthoDB" id="5105314at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="112" mass="12534" checksum="B8A2B3B5110E75F1" modified="2014-05-14" version="1">MSAWGVIIDTVVKGLTMAAHAATLVEKGRNFVRWVRGKEKKKDAKSEDLEMGPVGWRAEMEVLRGRVAAVEVENSALREVVNDLHLRFGGPLPSRRVDGVRRRSHVGHPHFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX92</accession>
    <name>X0BX92_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_09789</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX92"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_0_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936057" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="5">
        <location>
            <begin position="18"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="534"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="577"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK86521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="598" mass="64020" checksum="959D5A5371102F65" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXD9</accession>
    <name>X0BXD9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXD9"/>
    <dbReference type="eggNOG" id="ENOG502QSKG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_0_2_1"/>
    <dbReference type="OrthoDB" id="184880at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF105">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="37773" checksum="1630D19ABB8B27BE" modified="2014-05-14" version="1">MSSPKSPGKSPRSPQSPPGAVEAAETPAQQARDGFIQPASLIWPRTDVTDTESLRSSILNYKWVHGRRFHAYGDGTYCHELFRVVLNGKLYEAPIGKNPQNVLDVGCGTGIWAIDMADLHPSAEVIGVDLSPIQPNFIPPNCRFEVDDINKEWTFPENKFDFIHIRYMTGTVPDWTELLKKAQRHLKPGGWIEHVELWGDARADDDTMSPESPLKTWVKIFEQVGEKIGNPFFWNPADEFEKAGLKNITEKKVKVPIGTWAKDKDLKQWGAWNRQFLLQGLEGFSIRSLTELLGWEYEKAQVFLVEMRKELLNPKLHSYVLVTTVYGQKPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYC5</accession>
    <name>X0BYC5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12221</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYC5"/>
    <dbReference type="HOGENOM" id="CLU_026304_2_0_1"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF16">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK83524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="459" mass="51244" checksum="CD8FD30E84AAA8BF" modified="2014-05-14" version="1">MKATSCLQCREAKRRCVKQTIDSPCNTCQRKNLACSSHVSSQTTSASKETHESLPELTAELAIEFVESYLTHLDGLPHSIFHQETLRRQVRDKEIGDALLYSICALGSKFSPKSEHRALENPLTKEAKRLVQADLENVCIENVQTCILLSLLSAGNCHTSSETLFLRIAIGMAEVLQLNFSADGPSIVSETALRTWWSLYILDRWCSSGLGIPRHLDNPHCPDSSPLPIDETSFKCLRPSSSNQNSSRTPGVFAHMVTLIQHFGHIQGVNRVMAKGDMVPKVKCDAIKLIGQKLESWRTDLPENMQMTIQNIYSHQQNDLGGHFIALHLVFHHLSALVYFNSLETKEPSYIGQEDHIALCKSHASSFSSLLHTSRQMSGCQQNYPTVGHMTTVASAVLLHTLLLGEPKDIPKARRELNTNFEALIELRQYWPVTEAMVDDFPEDMPLVDGKSQVGRMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYF0</accession>
    <name>X0BYF0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7025 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980100">
        <property type="protein sequence ID" value="EXK75572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYF0"/>
    <dbReference type="HOGENOM" id="CLU_966580_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7025" evidence="2">
        <location>
            <begin position="124"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK75572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="288" mass="32310" checksum="F417623999BF8152" modified="2014-05-14" version="1">MPLYQFPNGNSLKLLLEKALEVDLASPIVFLKPFKVLVKYDGQIRNLHQQLEKKFSRDCAEPPTSSNTPEPSQTIGSRYSNDDGEAWNSLLDEYGTKQAFRQLSCLVEFMNKDLIPLRSFADSTATKIAFSDLWHIFQAGVTVVTATTPIEAYRVLHVTGGRPYLSPPEDKENDEEATGMNLYKVPAKSSDFIITCYQVGFDGDKFGPIAKSFSIQKYNGFQDIRLLPIYPMSFAEGPEELSKKLSGNGKTFIKLSNVGHVLYRGPNLYEAEEIDSEIIIDFRAALWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYM7</accession>
    <name>X0BYM7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19593</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979973">
        <property type="protein sequence ID" value="EXK75642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYM7"/>
    <dbReference type="HOGENOM" id="CLU_1865212_0_0_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15741" checksum="CEFB6CD022041545" modified="2014-05-14" version="1">MCIFIVVAGMEKTEIFSGRTNLVLAKEETNRLDLFHKFFLVARNNSLFSALLDVKKPLRVLDLGTGTGIWAIELSEKYPHMHVQGLDFNMIQPEMIPRTMEPPEPFDLEGPWDTVGTDWDLIHARTLFGSIRCWSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYQ1</accession>
    <name>X0BYQ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450 3A7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09129</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYQ1"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_25_2_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11070">
        <property type="entry name" value="CYP56-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK87295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="61605" checksum="8E6D1E548B3B57D0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZJ3</accession>
    <name>X0BZJ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08938</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZJ3"/>
    <dbReference type="HOGENOM" id="CLU_1610834_0_0_1"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF80">
        <property type="entry name" value="NAD(P)-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="165" mass="18145" checksum="F6D12F66357165FE" modified="2014-05-14" version="1">MDSSQTYSYQRCSSPCLRTEPAGCQYDTLATRGRTSVDKFLRYDAARWTDLRNAFEQAVAEAGRIDLATSNAGVSEQYDYFSDKSDEWGKLLEPAFGVTDVNFRAVNSGGIVITSSATAHALEHDLPVYDASKLATAELMRSLRSTFIMDDFTVNAVTPADTSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C041</accession>
    <name>X0C041_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C041"/>
    <dbReference type="HOGENOM" id="CLU_2004148_0_0_1"/>
    <dbReference type="OrthoDB" id="5022080at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="13604" checksum="5991B0BD4DED0269" modified="2014-05-14" version="1">MSSPITTDVGSPENSTPSDGMLAWLSAILLPIMALTMMFLVGEAKVFVILWSNIAYHSVIKLFTASGPAAPRLPCSSKNQQRHEVEHHEPCSRLVGCTSLQHDMVCLWTRHHSAPLTNRPLWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0C3</accession>
    <name>X0C0C3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08924</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0C3"/>
    <dbReference type="eggNOG" id="ENOG502RS7T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_1_2_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="36619" checksum="593E9C1731B2C7CA" modified="2014-05-14" version="1">MRDIAPRVRAKQPQTDSESLESLRSSVLRFQEENGRTYHAMSSGKYNFPNDASESDRLDLQHNLWLLTLQGELGLSPKIKEPAKRVMDVGTGTGIWAIEYADLHPEAQVVGVDLSPIQPSLVPPNCVFEIDDLEKEWTWSEPFDFIFCRVMTGSFADMEKFVQNAYDNLEPGGYLEMQDLTYPIACDDGTLPPDCEVLRSGLLSIEASAKAGRAINLAPKYKTFLEKAGFVDVVEKQFKWPINEWPKDKHYKELGKWSYANINNGLEGLLLGLFTRFLGWSADEVRVFCSAMRKQLRDRSIHAYIPVYVVYGRKPLEEPASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0Y5</accession>
    <name>X0C0Y5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0Y5"/>
    <dbReference type="HOGENOM" id="CLU_075107_0_0_1"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF10">
        <property type="entry name" value="MRJ, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="5"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="194"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="321" mass="37683" checksum="2A184035F26F12DA" modified="2014-05-14" version="1">MDFIDYYKILQLTPTANTDEIKTAYRQLAKTTHPDKNREDKQATSNFQKLNDAYSTLSDTEKRRVYDLEYERQRRLNQPRFYTIGRTSESTNKNAAPFPWFSATFYAEPPPFNPEPMRLFVKIRESEDFIRQFKSCVSSTGKEVRRQKRTIQKKEEAVRALKEDILKHGTEKTRKYAHGGGPSNLNRIKESPQIQAKTRRKAEMEAELKEQEEKLVSLERQFLDFSRRLSYWEKERDALGPKFEIACESDPLSSERWPFNTVRRRTKKKKQASPDVQPGTREEFEEAERRRRERKGESSQETHTSFQGESAAQSSNTTSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0C216</accession>
    <name>X0C216_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chromatin structure-remodeling complex subunit sfh1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_08551</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C216"/>
    <dbReference type="eggNOG" id="KOG1649">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014421_2_0_1"/>
    <dbReference type="OrthoDB" id="10258327at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="239"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="475"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="497"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK88166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="580" mass="64479" checksum="0761D2934B252C29" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2U0</accession>
    <name>X0C2U0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ADP-ribosylation factor 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_10571</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2U0"/>
    <dbReference type="eggNOG" id="KOG0071">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040729_9_3_1"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04149">
        <property type="entry name" value="Arf6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000832">
        <property type="entry name" value="ADP-ribosylation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041838">
        <property type="entry name" value="Arf6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK85488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="186" mass="20922" checksum="612AE62FE793D4C0" modified="2014-05-14" version="1">MGGQFSKMMGKIFGSKEMRLLMLGLDAAGKTTILYKLKLGQDVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYFSGTQGLIFVIDSSDRNRMEEARQELHRIINDREMKDSLLLVFANKQDLAEAMKPQEVTEALQLSKLKDKVWYVVPSCATTGEGLLEGLAWLSNNVKAPPTPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2Z3</accession>
    <name>X0C2Z3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2Z3"/>
    <dbReference type="HOGENOM" id="CLU_170482_0_0_1"/>
    <dbReference type="OrthoDB" id="3519400at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="89" mass="10499" checksum="473FA10BD2E9E7D0" modified="2014-05-14" version="1">MAHTTETYYYYVPNLQALDPTAREVDPSAYAWVQPTIIEDEDLTFGGKALSTWYEEDRRRHSSGSDEEERRGRERVRRNYSRSGKSHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C382</accession>
    <name>X0C382_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7704 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C382"/>
    <dbReference type="eggNOG" id="ENOG502S3HU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112091_0_0_1"/>
    <dbReference type="OrthoDB" id="5313995at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056121">
        <property type="entry name" value="DUF7704"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019:SF1">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24803">
        <property type="entry name" value="DUF7704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7704" evidence="2">
        <location>
            <begin position="15"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="166" mass="18821" checksum="8342F68F973B90AF" modified="2014-05-14" version="1">MATPTPRSAQVAFRIHPIYRIFFLILEPISALTGAFYTHFRQDTYLSLLHASSAPAETPKATSVAMSQLANMFFFFALNEALVLRSTADLRVWRTVLLVLLIADLGHLFSMSELGPRIYWDVMAWNASDWGNVPFVYLGMTMRLSFLMGIGLGESRALKKKDWKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3C2</accession>
    <name>X0C3C2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3C2"/>
    <dbReference type="HOGENOM" id="CLU_3384763_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="33" mass="3942" checksum="7A49F59C90CBE6CB" modified="2014-05-14" version="1">MSWADERFSQLTASDIIRRSQPHIERSLKELIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3U5</accession>
    <name>X0C3U5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3U5"/>
    <dbReference type="eggNOG" id="ENOG502SI1U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013296_3_1_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF40">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="234"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="599" mass="66988" checksum="CFB73419AE7EE1BE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5G9</accession>
    <name>X0C5G9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_17308</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 77 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658553">
        <property type="protein sequence ID" value="EXK77997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5G9"/>
    <dbReference type="eggNOG" id="ENOG502S9ID">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039661_0_0_1"/>
    <dbReference type="OrthoDB" id="3763672at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF3">
        <property type="entry name" value="NUCLEOTIDE-DIPHOSPHO-SUGAR TRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="5">
        <location>
            <begin position="122"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK77997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="299" mass="34928" checksum="3363EB691B960BE3" modified="2014-05-14" version="1">MSPTSPPPAKLAENIPQLMHHLWKPFLHDINATHFLTKEGYYYKYPKDTHRWSQPLRKKLLILDVDTRLDTGPGGIMNKTTLNSKGMTGRTAGMMSHYLYAMIHGYDYRFIRAPSYPNRHGTWVKVPMIREALKTHKIVVFLDADAIFMYPQLPFEWLMRLWNITDNTLVAMANDPNSPRNRDANGQVMQNTGFIIAQQSNRTQELFYNWEQCPTDIKYKGCKRWGKVWAHEQAAFSNHVRYDYNSTEEVRVIPCMDGNGAPYIGDKTCGGVFIRHHWFHKDYPIKDMHQLILDAFLYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7E3</accession>
    <name>X0C7E3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_09545</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7E3"/>
    <dbReference type="HOGENOM" id="CLU_004495_6_2_1"/>
    <dbReference type="OrthoDB" id="4476201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF26">
        <property type="entry name" value="OS04G0435100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="495"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK86709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="520" mass="56739" checksum="6C64851382CEB73E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C829</accession>
    <name>X0C829_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C829"/>
    <dbReference type="eggNOG" id="ENOG502SHFS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029538_1_0_1"/>
    <dbReference type="OrthoDB" id="5382058at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853:SF1">
        <property type="entry name" value="LIPASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029171">
        <property type="entry name" value="Esterase_LipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939196" description="AB hydrolase-1 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="139"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="479" mass="51938" checksum="C267139B6DE09215" modified="2014-05-14" version="1">MATLNFKRAFTLLLLSTSCVVAQNPFPDTTTCDKTCQARALNASSWISEQQSDPTFSFYKTPSSFSSKLAPGVVLKTEDVTNLDNYIVPSGLTMSRIIYTTEDLDGKIIPASAYVLWPYAPFSTGPGSTRKGLPMVAWAHGTTGTFKPCAPSSYRALQYHFQVPFALALQGIAVVAPDYAGLGVSEMPNGDTIPHSWVTAPAHANDVAFAVTAARSAFPDLLGSDGPFVAMGHSQGGGASWAFAERQVRKPLKGYRGTVSIAPVTRILDDYAYWTENSIASPGLLAQSAVIDSISKIYPKYNYTGFTSAGYDRWHNVIAKVKGCFPVLALVTMDLAPTDIVKSGWYKDPTAKKWADRVAVGRKTFAGPLLIINGADDHVVRPEGIDAAVKDTCDLAKKTGNKEAVEHATFSGMDHFSAIQASQMKWMDWVKSRLSGKTLEKGCSEELVEGLKTNDTIHTLGPNFFLSYFVTAESWKYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8J4</accession>
    <name>X0C8J4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_16325</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658486">
        <property type="protein sequence ID" value="EXK79032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8J4"/>
    <dbReference type="ESTHER" id="fusox-w9j8t9">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_5_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152137" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="51"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK79032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="566" mass="60985" checksum="A11DFC40FBA9BDC5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9C6</accession>
    <name>X0C9C6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_06886</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9C6"/>
    <dbReference type="eggNOG" id="ENOG502SFKU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_3_5_1"/>
    <dbReference type="OrthoDB" id="5320223at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK90701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="14798" checksum="3A3433062B6F23BA" modified="2014-05-14" version="1">MPLSGHCLCKAVTYKVDDEPLLVGYDHCDDCQRQSGSTYSLVAVVKKDKLTISGPVKTYSGSKGSSGNIVHRLFCPECGSPIAHDPDAAPEIIALKAGTLDTEIKKNLKPDTEIWTVSKLPFCQEHLAKPFSHMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAV8</accession>
    <name>X0CAV8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar iron transporter 1.2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_15643</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658459">
        <property type="protein sequence ID" value="EXK79807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAV8"/>
    <dbReference type="eggNOG" id="KOG4473">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038957_0_2_1"/>
    <dbReference type="OrthoDB" id="73465at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02435">
        <property type="entry name" value="CCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="FE(2+)/MN(2+) TRANSPORTER PCL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="29839" checksum="038A36FE57D889A3" modified="2014-05-14" version="1">MTHITSESTPLLPEPATERSISYQSSHPAYDARPLHPNYSKHEECHVDYSDILRDIIIGFSDGLTVPFALTAGLSSLGSAKVVIIAGLAELFSGMISMGLGAYLAAVTERDAYHSQAGKKEFAVQNRPGDERTGVYDVLEKYSVSRSAAAPLVDELCKNPTEWVRFMMDFELKLEEPNVHRAWISAVTMGLSYFIGGLIPMIPYFVMSRVREALFVSIGITVAVLLVFGYVKNYVAIRNHRAGVWGAVQTLVIGMLAAGTSYAIVRGLDSNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB36</accession>
    <name>X0CB36_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_06737</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB36"/>
    <dbReference type="eggNOG" id="KOG0128">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003925_2_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031766">
        <property type="entry name" value="RRM_occluded"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16842">
        <property type="entry name" value="RRM_occluded"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="600"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="677"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="768"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="896"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="539"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="855"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="984"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="872"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="984"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1065"/>
            <end position="1079"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK91336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1079" mass="120699" checksum="8B4B9ABAC086D1D4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCB9</accession>
    <name>X0CCB9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658448">
        <property type="protein sequence ID" value="EXK80302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCB9"/>
    <dbReference type="eggNOG" id="ENOG502SCQY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127592_4_0_1"/>
    <dbReference type="OrthoDB" id="447346at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052164">
        <property type="entry name" value="Anthracycline_SecMetBiosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33993">
        <property type="entry name" value="GLYOXALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33993:SF2">
        <property type="entry name" value="VOC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="11"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="133" mass="14843" checksum="47FBB0125E9B4562" modified="2014-05-14" version="1">MSEWKPPAFGTPVWMSIPATDVSRAAEFYKAVFNFSFKDSDHKNPDEFRKFDFNPSLGLTGGIQQAPDHTGNFHPGKGGLCVYWFVENVDNIGSIIEKAGGKMLTEKEKEGEFGLYRFFEDTEGSVGAVYQMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDC5</accession>
    <name>X0CDC5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDC5"/>
    <dbReference type="eggNOG" id="ENOG502RF1M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045417_1_1_1"/>
    <dbReference type="OrthoDB" id="5075194at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="289"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="379" mass="42786" checksum="4EF069BDA735F477" modified="2014-05-14" version="1">MATPLCIDIDQTAAIVEWEWEGATRCLATPDPDNVPIRFTIHIDSTHDQHRAHFEIIIPVKFKDKPSSAAVLLRISPLFITCFRFSTNIDPSDSIKKQRFDSAACLEFELGNTVAVLVPSYVKEPISASRPRSGKVLDSLYELSRVTTLRIYIQDSLLSLDQLSSISDRVTKGQLEPFSGPEYDISRMFSGSGAKATKLAPPKPPSYEKATSSQPPSAPSYQRKRPRQDSPQGPDSISQVWDKLQKLESLFHSKVGELTAENAKLRDQKLKPDESQAETTQPTDQSQVIIELRAENARLREEVERLKNRQEDLEAEVASLQTAQRSEKDTEEVAIIEIRDDIESLERRLSWVENGKDEYFMKQIKQEIFDELATRVLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDK9</accession>
    <name>X0CDK9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Transketolase</fullName>
            <ecNumber evidence="4 15">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_14834</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 15">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="12">Binds 1 thiamine pyrophosphate per subunit. During the reaction, the substrate forms a covalent intermediate with the cofactor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4 15"/>
    <dbReference type="EMBL" id="JH658438">
        <property type="protein sequence ID" value="EXK80702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDK9"/>
    <dbReference type="HOGENOM" id="CLU_009227_0_0_1"/>
    <dbReference type="OrthoDB" id="10267175at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000004">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF2">
        <property type="entry name" value="TRANSKETOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 13 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 15" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="16">
        <location>
            <begin position="354"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="115"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK80702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="683" mass="74466" checksum="32CBC31AE96035D5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDU4</accession>
    <name>X0CDU4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05539</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the actin-binding proteins ADF family. GMF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDU4"/>
    <dbReference type="eggNOG" id="KOG1736">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087056_0_0_1"/>
    <dbReference type="OrthoDB" id="3919494at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071933">
        <property type="term" value="F:Arp2/3 complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071846">
        <property type="term" value="P:actin filament debranching"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034316">
        <property type="term" value="P:negative regulation of Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11283">
        <property type="entry name" value="ADF_GMF-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000048">
        <property type="entry name" value="Putative gmf family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011171">
        <property type="entry name" value="GMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249:SF2">
        <property type="entry name" value="GLIA MATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249">
        <property type="entry name" value="GLIAL FACTOR NATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001788">
        <property type="entry name" value="GMF-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="3">
        <location>
            <begin position="6"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK92356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="142" mass="16282" checksum="56ECF9ECA1C91798" modified="2014-05-14" version="1">MASESRLYTFSGESKDHLRKFRLTTSRAKDPQAVIYLIDKNTYEIRQDEDKTVYTSLEEIGDDLPDHAPRFILLSYPLTMGDGRLSVPYVLIFYLPVTCNAEIRMLYAGAKELMRNTAEVGRIIDIESAEDLEEIPDKLKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGP0</accession>
    <name>X0CGP0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGP0"/>
    <dbReference type="eggNOG" id="ENOG502SK6S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5425848at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861">
        <property type="entry name" value="GLYCOPROTEIN 38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861:SF10">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738226" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK89999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="42535" checksum="75BC1B25028DAB88" modified="2014-05-14" version="1">MRSVTRPLLLLAAAALCSAKPLPRDGLHDRGYSYLMHRGCDSPCGSDNQYCCGSGETCQTSNGVANCVAAKGGWVGDYTTTWTETRTYTSTIMTRWEPAPEPTKGVDCVPKNDEQEACGEICCAGWQTCAFMGQCSAKPGYEEPTAVVITTDGKITTQYSAPYRVTGTTTITNSGAPTESETATETESEASATATETSEGAAAGETGTGGGGLSAGAIAGIVIGVIAGVALLLLLCFCCIARGLWVALFGKKDKEKSERVDVYEERYSRHGSRPPPSASAHSRRPRHKGWFGMGRRGSPSSAGDRREKKSDGKKWLGIAGLAATLLALLNLKKDKRPASTKPARSSRGSSRSRYSDSYYSYSDYTSPTGSSSSGGRTNRTRRTRDSRARSYYSRDSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHQ7</accession>
    <name>X0CHQ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Nucleolar GTP-binding protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_05114</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHQ7"/>
    <dbReference type="eggNOG" id="KOG2423">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011106_4_0_1"/>
    <dbReference type="OrthoDB" id="444945at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01858">
        <property type="entry name" value="NGP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000559">
        <property type="entry name" value="Nuclear/nucleolar GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024929">
        <property type="entry name" value="GNL2_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012971">
        <property type="entry name" value="NOG2_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF9">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08153">
        <property type="entry name" value="NGP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="9">
        <location>
            <begin position="222"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="474"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="481"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="533"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="566"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="604"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK93965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="620" mass="68995" checksum="AF2146994E6A54C0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHS5</accession>
    <name>X0CHS5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979330">
        <property type="protein sequence ID" value="EXK82142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHS5"/>
    <dbReference type="eggNOG" id="ENOG502SCX2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162806_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="99" mass="10267" checksum="55A2DC77DE345865" modified="2014-05-14" version="1">MSGYAQNERGQGLSHATAPSKLSEGIQRQMPKGLEHALPESIHPTESTPGSSGGISYAKGGEASLLPQKGQEGLPEGVKRAIPNAIHDTGDKGDANDKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJB9</accession>
    <name>X0CJB9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Diaminohydroxyphosphoribosylamino-pyrimidine deaminase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJB9"/>
    <dbReference type="eggNOG" id="KOG1018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051532_1_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF109">
        <property type="entry name" value="RIBOSOMAL LYSINE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="33768" checksum="949B1DCCA9B1895F" modified="2014-05-14" version="1">MDFVNSLLANLEPEVEDAEEETFMLYSQPIPSMNLGFVDSRAASVDVSVADRDYTIHQSPTVLSSSRAGGTTGAVLWKIAPSFASWLSSPSNPILANTIHSNASILELGCGISPLSALALGPRVARYVLTDQSYVQRLVQRNLDENFSSAFSSGTSTPTSGRGKKKRSGHGHGHGAAQPNIRFTTLDWETDEVTPSLTGSDEARSFDAVVACDCVYNYALVDPFVQACADACRLRLSDDEAFANDEERRPCVCVIGQQLRSDEVFESWLKAFSTSFHVWRASDSVLPAELRPSAGFVVHVGILRDEIKKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJK4</accession>
    <name>X0CJK4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MFS maltose permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJK4"/>
    <dbReference type="eggNOG" id="ENOG502RRIM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011673_1_0_1"/>
    <dbReference type="OrthoDB" id="5408102at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK94610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="552" mass="62066" checksum="6EA8303417A3EBB8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJX0</accession>
    <name>X0CJX0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S ribosomal protein L12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_06317</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJX0"/>
    <dbReference type="eggNOG" id="KOG0886">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074237_5_0_1"/>
    <dbReference type="OrthoDB" id="1478556at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="7">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="6">
        <location>
            <begin position="74"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK91588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="165" mass="17719" checksum="16F01401194AC1A5" modified="2014-05-14" version="1">MPPKFDPNEVKVIHLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVKLTIQNRQAAVSVVPTASSLIIKALKEPPRDRKKEKNIKHNKSVSLDEIIEIARTMRYKSFAKELSGTVKEILGTAYSVGCQVDGKPPQAIIEAIDSGDIDIPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CK37</accession>
    <name>X0CK37_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sexual development protein (LsdA)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CK37"/>
    <dbReference type="HOGENOM" id="CLU_045147_0_0_1"/>
    <dbReference type="OrthoDB" id="5293813at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937739" description="Sexual development protein (LsdA)" evidence="1">
        <location>
            <begin position="18"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="41424" checksum="104EC091FFA4F4D9" modified="2014-05-14" version="1">MKFTQIVVLLSSSIALAHPFGGKPSQPDSSDGYPFPTKEQLREISWRADGTLSNAPPPAKLGDSSKTAFQALAFGEEFEKAYFSSLLYNVTKNIHGYKSHYRYSKSELVKMFTTVVAQEELHAINAINVLKHFQVPAPLPCKYHFPTTNIDDAFSLAESFTMLVVGTLQDVSQTLAINGDNGVVRAIASVIGQEGEQGGFYRSLLGRVPSEKPFLTTSVGAFAFSYIYNNFVVPGSCPFDISIINLPILAKLDVEDASKGFDVKPRDQILTFTSDITGIENAERLITGIENAERLIGGNGDWLFLTYFSGQLLPMSEPISNVKWHKGHITFDAFFPFKENVMQGLTVAALTTSSKFTAPAMITEATIAGPGLIQVNDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CL88</accession>
    <name>X0CL88_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_12492</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658404">
        <property type="protein sequence ID" value="EXK83312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CL88"/>
    <dbReference type="eggNOG" id="ENOG502QV7F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_15_1_1"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03477">
        <property type="entry name" value="Rieske_YhfW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.10.10:FF:000014">
        <property type="entry name" value="Oxidoreductase, FAD dependent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038010">
        <property type="entry name" value="YhfW_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF281">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="453"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK83312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="551" mass="61079" checksum="D0A1CFB7D6DC14CF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLN7</accession>
    <name>X0CLN7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLN7"/>
    <dbReference type="eggNOG" id="ENOG502SQZN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026242_1_0_1"/>
    <dbReference type="OrthoDB" id="5138418at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="466" mass="51143" checksum="706CFF1A2016F4CD" modified="2014-05-14" version="1">MTIPSHFHMSGGFNREGVHPGLFRPPISPSSSTSYGYASPYSTATLDGQATKRKRPCHDISRSQEFRFQDDSDRNGYFGTPVAQMRNEEMRYQLAGQLDTPSSGPFDSGILGESMYSDTDYRKALGSKRTHDDIDHGAGPTQLFNLPPQPMQSQGWGSFAFSTIGGVVGRVWEFCKTGSFRGFQAGGGKAFTMNSGRVEELDQTLFESQHLPGRFPPSQEDYFNQRQPDNADQGGNSGASTPTAPHPKRRHTDTKDELGRNWVMVSDEKPAEPEPKPEPPLRRPSYRPSPRSRNSGPSMTTGRRISAAPSARFSSASTPGQRRSTTNRPTSRLSHAAASPTPRPASTASFASLAPLASPRIESPSRIPQPTRSTRRNTTISSPITKPSSHRRSHSNASVASGRTSAEASPRLTAEAKHLAARRKMEERDADVRINAFNKQLQDMIRQGREALGTTIEVEGNWEDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLS2</accession>
    <name>X0CLS2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_06437</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLS2"/>
    <dbReference type="eggNOG" id="ENOG502S93D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022088_1_0_1"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK91764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="474" mass="53054" checksum="A0429B253E62CF07" modified="2014-05-14" version="1">MPRVVLPDPAALNECLRNPLPTYSAVDNDDLLTRIEAAESVEFPILHSPAGRPTNLQRLTADVDWATYNEAYRVESDIVNAFFSAIEDGHDDIVADFIARGWVSPDTTSRWGETPLNAAVRAGKVPMVSRLVALGASVNEFGRARDGNSTVKAADLPERTPLMVAAERGHLALVKVLIEDYGAKHDLIAPDGAIALRLAAANRHREIVHYLPSIRGGAWKRWAVVHKKQMDRVRRAIDRIVKFVRILIWDLPKLLVWDAPKEICRAVWKRRHRVKTFFKELPGKVKDAVLEIPSTLKRAAKEVWKGIKELPSLLKSLVKAIFKVLWKILTGIPGAVMFVLKWIGSGLKGIGEAILNIFVKIFSLLHTAVMAVVTFLRGITLRDVWNGFCHLVRAIFVDAPKAIGAFFVAFGRTSYDVLKAIFGTLGSCIWFIGAGLLWLIHYIPRRIWTMIEAMGTSLVKAWEELMVFVNPKRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMH4</accession>
    <name>X0CMH4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMH4"/>
    <dbReference type="HOGENOM" id="CLU_2622142_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="78" mass="8472" checksum="2A593BA67EE22355" modified="2014-05-14" version="1">METGATSVRLLWEKPGESTSPLSSPAAPMLTVSSLVTWPCVVLETQLHFIDTPTPAPERNRQQQPRLFVKSALTANGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNK9</accession>
    <name>X0CNK9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_03033</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TBCB family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNK9"/>
    <dbReference type="eggNOG" id="KOG3206">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067577_2_0_1"/>
    <dbReference type="OrthoDB" id="5295208at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01789">
        <property type="entry name" value="Ubl_TBCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045172">
        <property type="entry name" value="TBCB_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF85">
        <property type="entry name" value="TUBULIN-FOLDING COFACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14560">
        <property type="entry name" value="Ubiquitin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="5">
        <location>
            <begin position="177"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK95726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="242" mass="26545" checksum="B89F79057818F356" modified="2014-05-14" version="1">MADVPLVVISEFAQSERRITPSWSISQLKGKLETVTGVPPSCQRLSLKPTAGAEAIAIEAPNEDDTHLSNFPLAPYAELHVIDTRPAASRINLNDTSGVDKYVMPEEEYEKKTDSVLAWKKAQKLGRFDPDAPSHEEAKLQALDREVATRGIAVGRRCRVGGEDTRRGVIQYVGEVKEIPGGLGSWVGVQLDEPVGKNDGSIAGTRYWGEPSELKHGVFVRPERVEVGDFPALDDLEDMEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ52</accession>
    <name>X0CQ52_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ52"/>
    <dbReference type="eggNOG" id="ENOG502SN7R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115501_0_0_1"/>
    <dbReference type="OrthoDB" id="5117488at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="206" mass="23102" checksum="6DC98A3BD1139A9D" modified="2014-05-14" version="1">MAPSWLEKFIVRGDATPDPRRSAEKPALEMHYTALIGHRRILGVNGDKTPRYEVERRAVLEIWGDKCYVKSLRQNAEVAMIDFHSIPPKTEVTFSQQSRTITMKGADGKYTAGGGLGELHWKPTGMVAYGKASWELRDKTGLVMSVTIDDQQINGMICLWKDGLTQEVEEELIMVGTSKIEEYRRLMRNSKVAAVGAVSNAFWLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ77</accession>
    <name>X0CQ77_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_02048</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ77"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF62">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="64"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK96605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="500" mass="55198" checksum="BCBBD14120194587" modified="2014-05-14" version="1">MSDEKPTVGGDDHKEIGSNLNDTPSIVQEKATDAFADINHVARLGMPNAAELEKKIVRKLDMWMLPQLWILYMFNYLNRTNIAQARLNTFNEDLNLGEGDYQTAVAVLTVGYMLAQLPSNMLITRVRPSIFLPVAAFIWSAISALTVLCTSAGGLWGVQFVLGIVEAPLFPGAVFLMSCWYTRREFALRVALLYSGLVLAQAFSGLIAAGVFAGLDGPMGLAGWKWLFIIEGAASGFFAITAFFVLPNYPDSPTGGATRYMTEDMRKLAAARILDDRVEFSEKSSVMHGLKLAVTDLKLYMFLFMNIFITSSYGFNNFFPTIVRGLGFGHNVTSLLMTAPPYVFGTLCTFYVSWDSDRRKDRGLHIIIPLSFSVIGFIVTVATGNAAVRYAMTFLYAAGCFSANTLQYTWAVSTLGQTPEKRAAGGAIVNIFGHLGNVISPYFFPDRDQPRYTMAMILQIVFASLGITLASIIKWHLTRKNKKMKAEADRLGVDFNPFTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQS9</accession>
    <name>X0CQS9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQS9"/>
    <dbReference type="HOGENOM" id="CLU_2236683_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="105" mass="11392" checksum="EE796ED9276CE84C" modified="2014-05-14" version="1">MRNRVWITILHALSSKPCPPLTEYLGTVNRGCVAICTGTSKELKPNMPCTDAALCTAQPHVGESTVICNLAVTFEDQDVPSSSEGRAGLTTTVCRGRLRRAFRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQX1</accession>
    <name>X0CQX1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxalate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11149</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQX1"/>
    <dbReference type="eggNOG" id="ENOG502S8GB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030515_2_0_1"/>
    <dbReference type="OrthoDB" id="10263073at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033609">
        <property type="term" value="P:oxalate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20305">
        <property type="entry name" value="cupin_OxDC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017774">
        <property type="entry name" value="Bicupin_oxalate_deCO2ase/Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051610">
        <property type="entry name" value="GPI/OXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03404">
        <property type="entry name" value="bicupin_oxalic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848">
        <property type="entry name" value="OXALATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848:SF9">
        <property type="entry name" value="SLL1358 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939548" evidence="5">
        <location>
            <begin position="23"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="153"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="331"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK84912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="495" mass="53086" checksum="B8A1A407FDC5BE6E" modified="2014-05-14" version="1">MVHRNTFFKALAASLSVAPGSALPAPQMGDYGENKGPVGGVKPPTPTVTSTSGSLYGDSSLLGGNAPLPDPDQDSAIVKDPKLVNGQAADPKLGLYLDFDGVDVPQPIRGELGATDPGPRTYDYEKLNPDLFAPPGTDAGDVPNAMWPLGLSHNRLGSEAGAGWARQQNQDVLPAATDMAGVDMRLAPNAYRELHCHTANEWALVTKGCLRVAAVNDEGKSFVDDLCEGDVWFFPAGIPHSLQAFDKGVEFLLVFDQGTFSEDETFLVSELFLRNPVSVLAKNFETETTAFDNIPKDELYIFNGTPAPKDIEKQNVTGSAGALTGNGSYTYHWSQQKPHTVPGGSVKIIDPTTFPIAKGFSAALVVVQPGALREIHWHTTSDEWSYFLQGSGRITVFKAASSARTFDFTAGGVGYIPAANSHYVENTGTEDLVFLEVLQAPKFSDVSVAQWLALTPKQIVKDHLKVSDKFLDSLPKEKAFIKTGDVNMTAIADEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSA0</accession>
    <name>X0CSA0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSA0"/>
    <dbReference type="HOGENOM" id="CLU_2740147_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="71" mass="8237" checksum="A0D46288E5829594" modified="2014-05-14" version="1">MRRKRISQPKTHVHATVQKVYRSTKQSRELNWDRFWCGCLAGDQGVFGPLEPGLRYPGSPQRVTVARQRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU63</accession>
    <name>X0CU63_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Epidermal growth factor receptor-like transmembrane-juxtamembrane segment domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_02784</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU63"/>
    <dbReference type="eggNOG" id="ENOG502QQEE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_375996_0_0_1"/>
    <dbReference type="OrthoDB" id="5240840at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049328">
        <property type="entry name" value="TM_ErbB1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21314">
        <property type="entry name" value="TM_ErbB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Epidermal growth factor receptor-like transmembrane-juxtamembrane segment" evidence="6">
        <location>
            <begin position="373"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="110"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="449"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="512"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="675"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="348"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="453"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="602"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="677"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK97666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="738" mass="78476" checksum="EC0595192804E4F1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUD8</accession>
    <name>X0CUD8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitotic checkpoint regulator, MAD2B-interacting-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUD8"/>
    <dbReference type="eggNOG" id="ENOG502S8PK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043185_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018800">
        <property type="entry name" value="PRCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13621">
        <property type="entry name" value="PROLINE-RICH PROTEIN PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13621:SF2">
        <property type="entry name" value="PROLINE-RICH PROTEIN PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10253">
        <property type="entry name" value="PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="40910" checksum="61FE3487B20BB491" modified="2014-05-14" version="1">MGLVDYSDSDGSGSEAEVQAPVKPAPKSSASSKKPFQKVVDRSNPGKIVVSLPQLVNDKPQAEEPPAKRTKTAGGGRFSGFNSFLPAPKNANKPKPVASSSSTARPTFQFKTSAAPGFSRETGGDLNNSNDNADGMSLPTPKAAAQPHIPEGQKPADEVKLVGKPLMFKPLSVARNPQKKKKKLNSGLAKPAPTPTHEQAQLKPAEATPEATPAVPKKVSLFSMHTEEPSEPVENSSSGTYEPMFATAESSLAYDEGAYGDYASHAQAGPSATTLPGSESLDTVVEDLNLTAAQRRELFGRNGLGNQAAKKVINFNMDKEYRHNEEIRAAGEEQTHNPVRAIQGGGKHSLRQLVQNAQSQREALEDSFAKGKNNRKEAGSKYGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVS8</accession>
    <name>X0CVS8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glycerol kinase</fullName>
            <ecNumber evidence="3">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_01448</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="3"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVS8"/>
    <dbReference type="HOGENOM" id="CLU_009281_2_3_1"/>
    <dbReference type="OrthoDB" id="5422795at2759"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07792">
        <property type="entry name" value="ASKHA_NBD_FGGY_GK1-3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000086">
        <property type="entry name" value="Glycerol kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000085">
        <property type="entry name" value="Glycerol kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042018">
        <property type="entry name" value="GK1-3_metazoan-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000756">
        <property type="entry name" value="PRK00047.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF69">
        <property type="entry name" value="GLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 10 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="12">
        <location>
            <begin position="93"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="13">
        <location>
            <begin position="359"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK98580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="606" mass="66653" checksum="B11652E1BE95FA7A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYC4</accession>
    <name>X0CYC4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYC4"/>
    <dbReference type="eggNOG" id="ENOG502T41I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_330381_0_0_1"/>
    <dbReference type="OrthoDB" id="5231758at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="868" mass="92238" checksum="104CD066A65AE726" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0A6</accession>
    <name>X0D0A6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Condensin complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_00448</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the CND2 (condensin subunit 2) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0A6"/>
    <dbReference type="eggNOG" id="KOG2328">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010510_0_1_1"/>
    <dbReference type="OrthoDB" id="362021at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022816">
        <property type="entry name" value="Condensin_barren_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108:SF9">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05786">
        <property type="entry name" value="Cnd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017126">
        <property type="entry name" value="Condensin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="8 11" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="191"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="287"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="595"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR017126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXL00176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="835" mass="91901" checksum="76481866E07E1ADC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0T6</accession>
    <name>X0D0T6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_00591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002333_0_3_1"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.690:FF:000001">
        <property type="entry name" value="Cell wall biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.700:FF:000002">
        <property type="entry name" value="Cell wall biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000100">
        <property type="entry name" value="Cell wall biogenesis protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041093">
        <property type="entry name" value="Dis3l2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17877">
        <property type="entry name" value="Dis3l2_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="3">
        <location>
            <begin position="744"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="600"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1189"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="513"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="537"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="607"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1214"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1241"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1270"/>
            <end position="1286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXL00401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1361" mass="149852" checksum="5AF4FCCE95BE607D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1E3</accession>
    <name>X0D1E3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_02591</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1E3"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="508119at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF21">
        <property type="entry name" value="QUINATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="391"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="31"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="508"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="518"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK97373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="531" mass="58003" checksum="3861E3BE4667DB36" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1U0</accession>
    <name>X0D1U0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_02696</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1U0"/>
    <dbReference type="eggNOG" id="KOG3313">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083737_0_1_1"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23156">
        <property type="entry name" value="Prefoldin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000001">
        <property type="entry name" value="Prefoldin subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016655">
        <property type="entry name" value="PFD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016396">
        <property type="entry name" value="Prefoldin_subunit_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR016396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK97533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="202" mass="23180" checksum="7D3C15217FEF94C7" modified="2014-05-14" version="1">MASKGKETAQSKDATPTNPRGIPYAPFVDKVEDYVSTRDDVEPTLRSFQEMISKYQFMEMNLQKRMGGLKEKIPDIQKTLDSVKFLKLRKDDDEAIDTTFELNDTLYSKAKIPATEEVYIWLGANVMLSYPIDEAETLLSSKLSTAKTSLSNCEEDLDFLREQITTMEVAIARVYNWEVVQKRKDKVEEEEEKKKKGKSQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2T1</accession>
    <name>X0D2T1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2T1"/>
    <dbReference type="eggNOG" id="ENOG502S3UC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115008_0_0_1"/>
    <dbReference type="OrthoDB" id="432412at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="13842" checksum="98D7EDE17969CED0" modified="2014-05-14" version="1">MSRTPSLFNCLIRTHHITSRKKLSRVRRAAQQLNVDWLYVRSGGSPGIMFAEGRDEAGLTEWVSTVQALRYKDFKCVAKPAKAEGVRGKTGFDETESVREFGRVMGEKGLGGWWKKAMGYEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0D379</accession>
    <name>X0D379_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_01012</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D379"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000009">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier-protein] synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005589">
        <property type="entry name" value="PRK07314.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF336">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="2"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="9">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXL01196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="445" mass="47355" checksum="F34AAEBDD77BEDBF" modified="2014-05-14" version="1">MMRRVVVTGLGAITPLGVGIRRTWTRLINNECGIVSVADLEPQARWEELTSTVSGLVPSGDGEGRWRASDWVNANEQRRMSKFTQYAIAASDMALRDSGWEPKNAEQQEATGVCLGSGIGNLDEIYETSLVHHQDGYKKVSPLFVPKILINMAAGHVAMKYGFQGPNHTATTACTTGAHSIGDAARFITMGDADVMVAGGSESCIHPLTFAGFGRARSLSTAYNDNPTASCRPFDADRNGFVVSEGAAVVVLEELEHAKARGAHIYAEIKGYGCSGDAHHMTAPREDGHGAYLAMKKALKSAGIKPSQVDYINAHATATHVGDVAETSAIKRIMLGEEGHQKESDVTVSSTKGAVGHLLGAAGAIEALFCILAIHEVCSFQSRKDAFTDYFQGVVPATLNLQKPDVGAAFNFVPNEAQEKTVGVAVSNSFGFGGTNSSLVFSRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D431</accession>
    <name>X0D431_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Suppressor of anucleate metulae protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D431"/>
    <dbReference type="eggNOG" id="ENOG502RVVP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033919_0_0_1"/>
    <dbReference type="OrthoDB" id="5424793at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="434" mass="49523" checksum="B35A4B150E0FFDEF" modified="2014-05-14" version="1">MGSTGKVALPEHWTELSAARVHRQQCADEVDAIKKTCLSECEKANVVECEKCFPKVLDRMRARYCDAEGREWFSERRAFLNELDVMFTDVKDHKKIDLKSIEDSIASEKEAWYRWVLRMYPQFLSVGDGGADQDELRAMLDDPVKRWEELTERIWEGVGKPANWEADVDSLTDQITVAKNDAASLKQIYINFFFKDSQTGEVVENAQQYLEAYAASDTMSIEQVIDRISQDRKASLMTEPQREHHRNRLDELRRAKMAFEQNRLQNKTRAQASQTPAVSQDLYNLPPCAVCAATVDPKDVLSCSVCQALAHMGGKRELTVWCSDECFEKGAGDHNELEHDCESGDRCVQYEDEDIEMQDWTSNAVACKECIDQKRDTIYCSIGCAASNLSRHRHEKHGLKTAAYEIKKLAVPLWEVVEKTLKEANPGLKYTVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5E4</accession>
    <name>X0D5E4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5E4"/>
    <dbReference type="eggNOG" id="ENOG502T6CC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049059_0_0_1"/>
    <dbReference type="OrthoDB" id="5058264at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="451" mass="50491" checksum="9254E57A92291B2A" modified="2014-05-14" version="1">MNSRPSFWGGTPSASGSRPSLKTGSIPHTESIDSRIESSRVMFGSPENYRLPDISELRSTDAGYFSPDLRHPGEKSLQTAQSSERNMETQEARSVSSPEAVSQSLRQLVESRITSPAGMFGGPEGLQLLSVREFRSQIAGYFSRDFNVPGPQFPEKPHDQCEKMDDVKARYEDLWLSTKLFWDLMLRIQPNSVTSDVEVLRPAVDLVLDVVVGRILPQLRPEYHPVLAESHLQALSRRLSALELRLQTDMGTCGKLPKMLCGCIITIKRPNNKDKLWTRHLTIRKDEKGRSEDQGFKFRDLASLLRLVNFSLASSPAADCGIIHIAIALMDDEIKRFIPKKDYNTADELKAEWIYVLCHGNFRSSIVLAVMGIVSDAVAFSKKDGTQIHGEECDHWAPETVPEPLTTAARLRKLTTFQADPNRGVSPLHPSYGKRNSKSSENTSLSRDRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5G5</accession>
    <name>X0D5G5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ataxin-10 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_01573</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a role in the regulation of cytokinesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ataxin-10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5G5"/>
    <dbReference type="eggNOG" id="ENOG502SC2U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005559_0_0_1"/>
    <dbReference type="OrthoDB" id="379794at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051374">
        <property type="entry name" value="Ataxin-10/CTR86_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019156">
        <property type="entry name" value="Ataxin-10_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255:SF0">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09759">
        <property type="entry name" value="Atx10homo_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ataxin-10" evidence="7">
        <location>
            <begin position="838"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="430"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="766"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="925"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="447"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="766"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="795"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK98798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="965" mass="109212" checksum="49EBD269674DCC7F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5N4</accession>
    <name>X0D5N4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Riboflavin synthase</fullName>
            <ecNumber evidence="4">2.5.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_07419</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.9" evidence="4"/>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5N4"/>
    <dbReference type="eggNOG" id="KOG3310">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034388_1_1_1"/>
    <dbReference type="OrthoDB" id="10258924at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000004">
        <property type="entry name" value="Riboflavin synthase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000006">
        <property type="entry name" value="Riboflavin synthase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006767">
        <property type="entry name" value="PRK09289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009566">
        <property type="entry name" value="PRK13020.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098:SF0">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lumazine-binding" evidence="10">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="9">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="9">
        <location>
            <begin position="102"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="10">
        <location>
            <begin position="102"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK89962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="234" mass="25081" checksum="9EDF2C3454E539AA" modified="2014-05-14" version="1">MFTGIVEEVGVVSNLNTNDSTGGTSLTISIPSGSKLLSDCHDGDSISVNGVCLTVTSFTPEAFTIGVAPETLRITNLGDLKEGSNVNLERAVRADTRMGGHFVQGHVDTTAEILSVEKDGNALTFRFQPARKDMLRYIVYKGFIAIDGTSLTVTKVNDDEAWWEVMLIAYTQERVVVAQKKKGDTVNVEVDMMAKYAEKSLGGVVGSEPGAAASFPFIEKIVERIVAQGFGGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0D646</accession>
    <name>X0D646_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01468</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D646"/>
    <dbReference type="eggNOG" id="ENOG502RP92">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153334_0_0_1"/>
    <dbReference type="OrthoDB" id="4995754at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK98614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="139" mass="16212" checksum="3217D6538317CD8C" modified="2014-05-14" version="1">MPIVNPTATSVPEEPKASESRPMSRLEIGLIVGVSVLFVTLIFSIFLVQALDHRRRKKVLRRMAEDARNRTPEEEMLYRRLAWLQVERIIQSLRCVWVDKDNNPTDPPPEVVEFHRRKGRISYQKPHMPQSEPQSKEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6I5</accession>
    <name>X0D6I5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6I5"/>
    <dbReference type="eggNOG" id="ENOG502RKP2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1643771_0_0_1"/>
    <dbReference type="OrthoDB" id="5077305at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="164" mass="18356" checksum="19D9F6C158F7B4D0" modified="2014-05-14" version="1">MSLTGDKQRLAMCYGYVLVAMAQLSLVIVASVLHKDITPYTTAVCKSYQRATRITSGMAFLLMAVQVYLSVIVTLLDGPKVVIMWFLIAQLVSTVYFCYIPFKYLKGVAPPMEDEWLLADQDDLELKLLSDKMDPSSLNGQSRVADYKTMELVRLSRPGDACRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6W2</accession>
    <name>X0D6W2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">NADPH--cytochrome P450 reductase</fullName>
            <ecNumber evidence="18">1.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">FOQG_01624</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">This enzyme is required for electron transfer from NADP to cytochrome P450.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="18">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.4" evidence="18"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6W2"/>
    <dbReference type="eggNOG" id="KOG1158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_17_3_1"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000036">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000032">
        <property type="entry name" value="NADPH-dependent diflavin oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023208">
        <property type="entry name" value="P450R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF108">
        <property type="entry name" value="NADPH--CYTOCHROME P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000208">
        <property type="entry name" value="P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 18" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 18" id="KW-0521">NADP</keyword>
    <keyword evidence="12 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="17" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="13" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="16" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="19">
        <location>
            <begin position="86"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="20">
        <location>
            <begin position="284"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR000208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EXK98879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="708" mass="78467" checksum="08B1B9746E98D6B8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8C7</accession>
    <name>X0D8C7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein ecm33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_06992</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8C7"/>
    <dbReference type="eggNOG" id="ENOG502QUZC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035846_0_1_1"/>
    <dbReference type="OrthoDB" id="536881at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.20.20">
        <property type="entry name" value="Receptor L-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051648">
        <property type="entry name" value="CWI-Assembly_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036941">
        <property type="entry name" value="Rcpt_L-dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018:SF3">
        <property type="entry name" value="RECEPTOR PROTEIN-TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738237" description="Protein ecm33" evidence="7">
        <location>
            <begin position="21"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="342"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK90872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="42235" checksum="44F239AEB8AC3580" modified="2014-05-14" version="1">MHSVKVLSAIAALSVSAVSAATCTKDVKITEPTQVISCDVVDADVIIDKSVAGAVVINGPKQIKGNFQAKNAGDLISISSTSINSITGKFELNNLEALNNLDFSSLESLGELSFIKLPRLGQLNFGTEGVTKIKSIRITDTFISDLSGLSVASVESFQIDNNRKMNVFNSDLVNVTTQLLIFDNGNDVMEITMNKLETAAEIQISSAKSFKVPALQEVTKSLKLSANPELKSFSAPNLTTITETLSLIDMNKLTNVSFPALEEIGGGFTIQNNTKLEAIDDFPKLEKVTGGIALRGSFEKVELPKLDQVSGSVVVSSTTDIKEFCDYFDNLKKDKKIDGEEKCTSNNKAANEGKDGGEESNGSSGSSNSDDQKDAAGIVSVNMAVLALAGVAAVAQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8K5</accession>
    <name>X0D8K5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Succinate dehydrogenase (Ubiquinone) flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8K5"/>
    <dbReference type="eggNOG" id="KOG2273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007739_1_1_1"/>
    <dbReference type="OrthoDB" id="71672at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06869">
        <property type="entry name" value="PX_UP2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047168">
        <property type="entry name" value="LEC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024554">
        <property type="entry name" value="LEC1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024555">
        <property type="entry name" value="PX-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185:SF1">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12825">
        <property type="entry name" value="DUF3818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12828">
        <property type="entry name" value="PXB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="207"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="876"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="946" mass="108014" checksum="A858F59B334CF4C2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0DA74</accession>
    <name>X0DA74_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7 11">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_06259</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 10 11">Belongs to the peptidase C12 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7 11"/>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DA74"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09617">
        <property type="entry name" value="Peptidase_C12_UCH37_BAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000009">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017390">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041507">
        <property type="entry name" value="UCH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF16">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18031">
        <property type="entry name" value="UCH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038120">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 10" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 10" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="13">
        <location>
            <begin position="10"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 10">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 10">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="9 10">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR038120-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038120-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK91492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="330" mass="36950" checksum="ED3BA2783F27E3D6" modified="2014-05-14" version="1">MIELCLRTVEIGELIRSCQGVFTSLIENLGVKDVQFEELLTLDPSELLSLQPVYGVIFLFKYPTDQPYATPEGPRDGSFDNAASENIFFAAQTIQNACATQALLSVLLNKTKDVEIGEKLGEFREFTMVLPPEFRGEALSNSDLIREVHNSFARSSPFADETDKTGAEAEDAFHFIAYTPINGTLYELDGLQPAPISHGACSSDDFATKVVDVLQRRIARYDTTEIRFNLLTMCRDLRQRARDFGDEELLAREERKRRDWMFENALRRHNFVGFAGEVMKGVVRSKIAEGGDAAYEKWVKESLERRKNAEQAMRGRAGGGHGDGDVDMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0DGH6</accession>
    <name>X0DGH6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">pectin lyase</fullName>
            <ecNumber evidence="7">4.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_04844</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.10" evidence="7"/>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DGH6"/>
    <dbReference type="SMR" id="X0DGH6"/>
    <dbReference type="eggNOG" id="ENOG502QXM6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021980_0_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047490">
        <property type="term" value="F:pectin lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000003">
        <property type="entry name" value="Pectin lyase F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF16">
        <property type="entry name" value="PECTIN LYASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938295" description="pectin lyase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="10">
        <location>
            <begin position="94"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK93587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="375" mass="39371" checksum="3470936668DBBAFE" modified="2014-05-14" version="1">MPSLFQTLFAVAAALPSVLGALPTRAEGFGSSTTGGGNAGAVYPKTAAELVSYLGDSSARVIYLDRTINFIGTEGTASETGCAPWGTGSKCQTAINQNNWCGNYQPNAPKVNVKYDKAGILGIKVGSNKSLIGVGSKGVIRGKGLRIVGSKNVIIQNVHITELNPQYVWGGDAITLDNTDNVWIDHVTTSLIGRQHIVLGNNACNRVTISNSKIDGTTSWSASCNNYHYWGLYFAGSNDLVTFKNNYVYRVSGRGPKVSGNTLLHAVNNFFHDVPDHAFEIDSGSVLAEGNIFQNVKYPVDSKGYQGQLFGVPTSGSACAASLGRNCQLNGFGSSGTLGGTNTGFLSNFKGKTIASASDYNSAKSVMTSAGFGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0DNF0</accession>
    <name>X0DNF0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 9B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03120</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF9 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DNF0"/>
    <dbReference type="eggNOG" id="KOG3334">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068315_0_0_1"/>
    <dbReference type="OrthoDB" id="341924at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07979">
        <property type="entry name" value="HFD_TAF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000069">
        <property type="entry name" value="Transcription initiation factor TFIID subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003162">
        <property type="entry name" value="TFIID-31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051431">
        <property type="entry name" value="TFIID_subunit_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068">
        <property type="entry name" value="TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068:SF4">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02291">
        <property type="entry name" value="TFIID-31kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="201"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="253" mass="26300" checksum="509FB28CD8428989" modified="2014-05-14" version="1">MSSSQPQTNGVPASSAGTSQTVPNTQTTAASSSQPAAAASQNAPPPAPSTTAPRPRDSRLIELLLTSQGVTAYEPRVPLLLLDFAYRHTSSVLSDALHLSGDPYVTQAGSKPSANAGAISAPAGDAAVTANAVKLAIAARLSYQFRGGNAGGGISKDYMQELARERNKVALPKIVPSEWGVRLPSERFVLSGTSWGLKDVWDEEDDEEEDQGGDAMEGIEGPEPEDIGGDGVEGGTVEDMFGEDVDEEMAEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0DT74</accession>
    <name>X0DT74_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DT74"/>
    <dbReference type="eggNOG" id="ENOG502RNMU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130481_0_0_1"/>
    <dbReference type="OrthoDB" id="5231339at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="166" mass="18426" checksum="CB8F742CDAB7D778" modified="2014-05-14" version="1">MPPSEKKWDANAERDLCVAVIMGAQDGERMRFNWPKVHASMATLGYSFTKDAISQHFSKSIMRDFKGRHGDPSTSTPTATPKKATTRRKRSTPAKKKIEILDEEDDDAETMVESPVHKKMKHKNEDEDEDEDLKTSVGVQGKSGGSLSAAEKEAKFENWLANGDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0DY48</accession>
    <name>X0DY48_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DY48"/>
    <dbReference type="eggNOG" id="ENOG502SVPQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059046_0_0_1"/>
    <dbReference type="OrthoDB" id="4755094at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="55"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="423" mass="47395" checksum="7778E34A5FC6ECC1" modified="2014-05-14" version="1">MDPETARHENSQKQAEDHTTKQGSPQTPALKDKLASETHLRRFTENVLDSRQQEIENRESEKGQLAVEAETLRRQLAVTQRQLAEAQDQIFRLQPRRRDITEAEAREAYKILVGNVQRWVENRAAYAIEDLEIGRLAARASSPEGLRLVSLLREQSRRCLSVTQSDEFHITGVIMNYLHVTLFSKSFYCPLDDTEGDGTSRWVDDLENTMSRLPRDTAHCREWRSETLTALTHQPSFRTRRQRFLNFVVDDLTTLLSIIAPKSPPAELHSSVRRSIVEPAADLAHQLHLAPSVYSLKWPARTAATRLEVYQCLNLANGGAILDLSGTKAASQARRGVIYLFDIAPGLFVERVEGGRKLGLKAIVKPTVLVTNSGGDVLQGPTIMSFLWNNTPTSQGTSRSTSRASSSRRPAGSVISASSRQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0E109</accession>
    <name>X0E109_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00362</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E109"/>
    <dbReference type="eggNOG" id="KOG0634">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_5_1"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF1">
        <property type="entry name" value="AROMATIC AMINO ACID AMINOTRANSFERASE, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="279"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="82"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL00028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="622" mass="68798" checksum="E948FCB5A82AE17E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0E3X8</accession>
    <name>X0E3X8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PHD and RING finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00882</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E3X8"/>
    <dbReference type="eggNOG" id="KOG0825">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026721_0_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15545">
        <property type="entry name" value="PHD_BAZ2A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047157">
        <property type="entry name" value="PHRF1/Atg35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618:SF20">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="152"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="346"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="453"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="398"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="413"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="465"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="527"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="545"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="557"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL00983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="75007" checksum="C437E02DC0FFEEFC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0E4Q9</accession>
    <name>X0E4Q9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E4Q9"/>
    <dbReference type="eggNOG" id="ENOG502SFXF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074619_0_0_1"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846:SF1">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="2">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXL01213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="243" mass="28839" checksum="768C7297D358963C" modified="2014-05-14" version="1">MTSKRVSLPCRPRTTTSPMVRLKDDFFRPVPVVKKEPKAPRQRRKFTRLCPEFRNDGDCEQGESCKLFHFVPWELPGKQFTDYPVDLFFANFKEFDYQRTKPFFDEFYRMCDHFGWSDEEATEPWYNFRVSLIQEFNYVVGEDKDNLLHWQNMFNLIGLPKPTSLHEARTTMRVTHVNLVDLVESPRTRQPVEHFKTVQDLSQYSVYEVKIFPKEEAYNGGLLALLLREILGARSGRARRARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1T8</accession>
    <name>X0B1T8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979924">
        <property type="protein sequence ID" value="EXK75686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1T8"/>
    <dbReference type="HOGENOM" id="CLU_2831315_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="66" mass="7480" checksum="908BA2B0421DA26C" modified="2014-05-14" version="1">MTIVWTEMRVMPVTHLLIGPQNVFPLALAASTTIFSFNPLPIFMETLSSRSLTKPVLWERHGPNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3W2</accession>
    <name>X0B3W2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_18815</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979506">
        <property type="protein sequence ID" value="EXK76446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3W2"/>
    <dbReference type="HOGENOM" id="CLU_079101_0_1_1"/>
    <dbReference type="OrthoDB" id="1915122at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="6">
        <location>
            <begin position="91"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK76446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="164" mass="18885" checksum="8300331C94A3E10A" modified="2014-05-14" version="1">MIAQHEEEQYRYYHSILWEGIKTGVFGLVFGITLATGLRRFYSPFRQLPLYVKSTTCICPGMLTISIGANRESHAFHSYLHPELRSYEDEAEAEQEVKRIYAEESAGQRAKDWLYDHQFQVLGGTWVTTMAVALMHMKRDHSTWGARNLVQARVAAGVSTLFFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5S5</accession>
    <name>X0B5S5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658640">
        <property type="protein sequence ID" value="EXK77121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5S5"/>
    <dbReference type="HOGENOM" id="CLU_2722313_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="72" mass="8019" checksum="C5E634168EBC8CEC" modified="2014-05-14" version="1">MASSLRTILMPSAMWPKKSLRGRPHQHHRGRQTTEEISTSCGRIKSASIDPTIPCLPGALWFTFPSISRLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6Y8</accession>
    <name>X0B6Y8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7703 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658562">
        <property type="protein sequence ID" value="EXK77900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6Y8"/>
    <dbReference type="HOGENOM" id="CLU_045148_0_0_1"/>
    <dbReference type="OrthoDB" id="405906at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056120">
        <property type="entry name" value="DUF7703"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013:SF4">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24802">
        <property type="entry name" value="DUF7703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7703" evidence="2">
        <location>
            <begin position="9"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="343" mass="38793" checksum="DA09453405900DBF" modified="2014-05-14" version="1">MAIGEGYRGGVKVAIPIAMTMAAFFGISLYNVIEINVQIFLRFRKRTGLYFWSLMFASWGIAVHSIGFLLQFFQICRNSYVNITIITIGGVSMVIGQSVVLYSRLHLVVDDRRKIRWILKMIILSFFLFTVPPTVLNYGSNSPHPQAFLRPFEIYEKIMLFGFATQELIISSLYMWEARKMMRLLSPNSSETARRVMRHLIYINILVILMDISIIGFELGGAHVIQTTYKSAVYSVKLKLEFPVLNQLRAVVKRGGYTCNCSGPQVSFIADEAMTPRPGYELVPRRHSSMTNTFLSTQQPSIFSGLNLASSLQPIKVRSHNIEHRFISDPPPAQPQDYAAGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7H3</accession>
    <name>X0B7H3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658545">
        <property type="protein sequence ID" value="EXK78110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7H3"/>
    <dbReference type="HOGENOM" id="CLU_033910_2_0_1"/>
    <dbReference type="OrthoDB" id="5324651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="286"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="386" mass="43893" checksum="77C6662F9ABBFB67" modified="2014-05-14" version="1">MDPAVTVQLNDQDVYQATKDIFVGQKARFRKVRPVRKSIESCSRRDDTVRQFVALYGAEAICQIVLRLLSGGVYESPLTASRRFPDLFNPSVVQSAARDILEAEAIRSEQTALEGIVQSQLTDSQETFNWTEIMVALRDSGNNVPNGQTSNSSSLFPVYLPFPTEHLLMERLQKTLELACYEFGARAMPDTLRNRGWDCPESVELSKWTEVLKREGVLKRENTRKTLKELLYSIANIRHTAVHRLRTSSVGLEMFIADAEDLVEVLGDTAYSKSISQLRTNMNSAITELTQNKQFLQLQLEQTRAAIERQRAELDRREQEAIDYAREEDRKYQILAGEKVQQALEVIGNFEVTTNISISPPECFDGIEDMGDDDDDDMDQFEDCDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7T3</accession>
    <name>X0B7T3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979375">
        <property type="protein sequence ID" value="EXK77826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7T3"/>
    <dbReference type="HOGENOM" id="CLU_3351190_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="37" mass="4035" checksum="34E89776B1DC7149" modified="2014-05-14" version="1">MGQQILRLLKESSEDNVGTDLFIGKIAGAVYLREGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-05-29" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9Q3</accession>
    <name>X0B9Q3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trehalase</fullName>
            <ecNumber evidence="3">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_16819</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="3"/>
    <dbReference type="EMBL" id="KI979358">
        <property type="protein sequence ID" value="EXK78501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9Q3"/>
    <dbReference type="HOGENOM" id="CLU_006451_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011120">
        <property type="entry name" value="Trehalase_Ca-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF6">
        <property type="entry name" value="CYTOSOLIC NEUTRAL TREHALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07492">
        <property type="entry name" value="Trehalase_Ca-bi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neutral trehalase Ca2+ binding" evidence="4">
        <location>
            <begin position="354"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK78501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="739" mass="83755" checksum="655318158853828C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCR7</accession>
    <name>X0BCR7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979343">
        <property type="protein sequence ID" value="EXK79955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCR7"/>
    <dbReference type="HOGENOM" id="CLU_2184109_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="109" mass="12357" checksum="C41331B9FA15B9B0" modified="2014-05-14" version="1">MELDAFACSLIHNTWIRDEPDLTETDIRCGKQIAGRVDTVSRQATFLGEYFLRCLIADARKLRTFTVRYRPLSEPEVAIDTVSKACRGKMGVVIGNAESKQTAYRTKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCY8</accession>
    <name>X0BCY8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979529">
        <property type="protein sequence ID" value="EXK76354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCY8"/>
    <dbReference type="HOGENOM" id="CLU_220812_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="34" mass="3920" checksum="65FFD271EEF853EF" modified="2014-05-14" version="1">MGGIEEDERSNSGKEELGVVRTRTGREVKRPRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD23</accession>
    <name>X0BD23_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979459">
        <property type="protein sequence ID" value="EXK76703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD23"/>
    <dbReference type="HOGENOM" id="CLU_476518_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="572" mass="63865" checksum="FBCCFFCC1B4D274F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDN8</accession>
    <name>X0BDN8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">P-type Na(+) transporter</fullName>
            <ecNumber evidence="19">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">FOQG_18334</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="19"/>
    <dbReference type="EMBL" id="JH658663">
        <property type="protein sequence ID" value="EXK76938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDN8"/>
    <dbReference type="eggNOG" id="KOG0202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008554">
        <property type="term" value="F:P-type sodium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02086">
        <property type="entry name" value="P-type_ATPase_Na_ENA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000015">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000020">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000039">
        <property type="entry name" value="Sodium P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000047">
        <property type="entry name" value="Sodium P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="17" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 23" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="326"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="790"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="827"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="868"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="915"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="968"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="1001"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="24">
        <location>
            <begin position="23"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="EXK76938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1072" mass="117739" checksum="B1FE2CE92EAC64AD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE86</accession>
    <name>X0BE86_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658452">
        <property type="protein sequence ID" value="EXK80126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE86"/>
    <dbReference type="HOGENOM" id="CLU_1619100_0_0_1"/>
    <dbReference type="OrthoDB" id="5340195at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18672" checksum="7C2D8230414AF70E" modified="2014-05-14" version="1">MPSKPLMKQIAAGRRKPNLTRKEFLDHRFRIHGQIADAPEDKDLKPQWTALCRFETSISLMAWEKPVEVPTRLASERSNVPLNKDDAIVAMYFISTPDDAREGQQLETTLTPLLIKALEEYSQDEVWGLIANIGIVSERFDVNAYFGGVTMPQYSLVYVVYIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFG9</accession>
    <name>X0BFG9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979407">
        <property type="protein sequence ID" value="EXK77194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFG9"/>
    <dbReference type="HOGENOM" id="CLU_663997_0_0_1"/>
    <dbReference type="OrthoDB" id="5097247at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="336"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="400" mass="45171" checksum="F3FF61C6BFE53C86" modified="2014-05-14" version="1">MSTASAEKPDSGPTLRSSRLPDKSSVLLTDDELRTARDLNPVTRITSHRRLSELEFPREWVEDDGALAIVLRDWREQVEGMKQSNTHATKEKPDQVSDIPTEADIEVDSDVSFLSYPMKREAHWVEKTKELEKKLRQSEQEKQSAMQHNLKLQLELEALQRKAKSLYQALFDPDNRIHEANVMAKVKLHGEIRQLEKSLDAANNKNESLVKKNKDLESCNKDLITENEELVKKSQELESSNKNLVTEKEALAEENRDIDSDNGDLIATSQDLLTKISLARDAAKSYKELLTANNRALESSNKVLAKEITALKTSNQCVVAKSSKLKERFEQSVIAAKSCKERLDKIASKVKELESSKNTLAAQNKDLMDRNSALADMNKRLEESLEKIVTDAKCSLQSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGK8</accession>
    <name>X0BGK8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_17329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658554">
        <property type="protein sequence ID" value="EXK77983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGK8"/>
    <dbReference type="HOGENOM" id="CLU_013929_8_3_1"/>
    <dbReference type="OrthoDB" id="5396311at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF74">
        <property type="entry name" value="POGO TRANSPOSABLE ELEMENT WITH KRAB DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05225">
        <property type="entry name" value="HTH_psq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="HTH CENPB-type" evidence="6">
        <location>
            <begin position="113"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="88"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK77983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="359" mass="39996" checksum="D310FCC84DDA5582" modified="2014-05-14" version="1">MSSPSITHLGSPETPTTTPSHAMLGWLAPILLPLMALTILFLATPSTQAEFSPNLIDGTPSAVVHSNYTEDDVAEAILDITDRGLSQNEAAQKRGVPQSTLSRRLSGQVSRNERIQAHQRISKSQDEAFIRWVLRQESLGYALSHSQLRACVEAILKQQGDNKPLGKHWITRFVKRHPKLSIKLGKCQEAARFDGFTPKAVNWYFDIRENECGWIKPENTVNMDEGGIMAGFGLDSLVIGSSDPKKKAMLKGVQSRTWTSFIEAVTASGRSLKSGIIFKGKELQTQWFLNEFELIADWHYITSPNGWTDNHIALEWLKDVYLPETEPRDASDARLIILDGHGSHAHVSILVFSPQSYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGS7</accession>
    <name>X0BGS7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1479 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979368">
        <property type="protein sequence ID" value="EXK78053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGS7"/>
    <dbReference type="OrthoDB" id="8249012at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010856">
        <property type="entry name" value="Gig2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613:SF1">
        <property type="entry name" value="DUF1479 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G09280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBIU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07350">
        <property type="entry name" value="Gig2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="53764" checksum="5BA3EABE813A95DB" modified="2014-05-14" version="1">MNHSKPRAEKAEGSIGNSFASLAGEKETLLPERYLNLKREIIGDKSNQDALTAAWARLTARLAELSDEIEEKQQRTIPEATYHELVENPSFELVQRIRQCGSVVIRKTVSEEQALKWLDDVREYIKLNPQVKGFPEDDKQVYEIYWSKAQQQARSHSQMLKTQAALLSIFTAAPDCKVSLTSPLVYSDRLRIRNPGDAKFALVPHMDGGSIERWEDPTYRQVYEKILTGNWEEFDAWEMDKRADAVHDLYPGPGSTGLFRSWQGWTSLSETGPTEGTLLVYPFIREHTSYLLMRPLFKPKKPKSEFQDRKAYLSPDNWELDFDTTNFPGSPHHRNQELNDETHPHLELPRTMVCMPKVYPGDSVWWHSDVIHAVESRHNGKNAAAVFYIPAVALTPKNMEYIRDQKATLLSGRPPPDFPGGTGESEFKSRGTGDDLLTVEGKEGIGLVPFKLEDTMSETERLTRQAANSILGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI72</accession>
    <name>X0BI72_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_16775</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH658515">
        <property type="protein sequence ID" value="EXK78558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI72"/>
    <dbReference type="HOGENOM" id="CLU_005513_5_0_1"/>
    <dbReference type="OrthoDB" id="5584477at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="5">
        <location>
            <begin position="271"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="496"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="544"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK78558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="784" mass="88993" checksum="E8294E7F265E7C5E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIB1</accession>
    <name>X0BIB1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_16718</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="KI979354">
        <property type="protein sequence ID" value="EXK78603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIB1"/>
    <dbReference type="HOGENOM" id="CLU_031730_0_2_1"/>
    <dbReference type="OrthoDB" id="6038816at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF11">
        <property type="entry name" value="GLYCOSYLHYDROLASE FAMILY 61-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936335" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="17">
        <location>
            <begin position="20"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="18">
        <location>
            <begin position="262"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="233"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK78603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="298" mass="31244" checksum="3AD622113406E658" modified="2014-05-14" version="1">MKIATSLAAVVALVQSTSAHYIFQQLSVGSTKYPVFQYIRQNSNYNSPVTDLDSNDLRCNVGASGTNTQTVGVKAGDSITFTLDTAVYHQGPISVYMSKAPSSASSYDGSGGWFKIKDWGPTFSGSTSTWPMYLSYTFNLPTCIANGEYLLRIQSLGIHNPWPAGIPQFYISCAQISVSGGGSTVPSNQVKIPGAFKETDPGYTANIYSNFNSYTIPGPAVFSCNGAGGGDGGGNGPTTTLQTSTRASSTQVPPVSTQPSGQCASLWGQCGGSTWTGPKCCATGTCKALNDFYSQCTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJX9</accession>
    <name>X0BJX9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Amine oxidase</fullName>
            <ecNumber evidence="15">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_16600</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16153"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:228804"/>
            <dbReference type="EC" id="1.4.3.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="15">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="14">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="14 15">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="15"/>
    <dbReference type="EMBL" id="KI979353">
        <property type="protein sequence ID" value="EXK78749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJX9"/>
    <dbReference type="eggNOG" id="KOG1186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011500_3_2_1"/>
    <dbReference type="OrthoDB" id="5379943at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.20:FF:000001">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.40:FF:000014">
        <property type="entry name" value="Peroxisomal primary amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049947">
        <property type="entry name" value="Cu_Am_Ox_Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF86">
        <property type="entry name" value="COPPER AMINE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01165">
        <property type="entry name" value="COPPER_AMINE_OXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 15" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="17">
        <location>
            <begin position="6"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase N3-terminal" evidence="18">
        <location>
            <begin position="96"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="16">
        <location>
            <begin position="223"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="13">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="14">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK78749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="671" mass="75522" checksum="DCA825587A44DBB6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKI6</accession>
    <name>X0BKI6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_15971</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658472">
        <property type="protein sequence ID" value="EXK79408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_1_1"/>
    <dbReference type="OrthoDB" id="5086500at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="5">
        <location>
            <begin position="393"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="892"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="926"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="960"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="994"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1062"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1096"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1130"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1164"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1198"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1232"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1266"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1300"/>
            <end position="1323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK79408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1504" mass="168373" checksum="95F5D5E3897004FC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM33</accession>
    <name>X0BM33_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658453">
        <property type="protein sequence ID" value="EXK79968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM33"/>
    <dbReference type="eggNOG" id="KOG4781">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052827_2_1_1"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF1">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="101"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="197" mass="21170" checksum="B79D10A0EB2BAF73" modified="2014-05-14" version="1">MSTEVRPSPTSGSQTTQDLYQRLASIAASHPATLDLQGKINVEVTRSVLSVREEHIQDNLTSTTLAGLHAISPPPFVYKDDAAGGLLAFYHLGHKLSGHSGLVHGGIAAVLLDECMGRASFPRLTGKISVTANLNLNYKSPIEVDSIILIRADVMEVQGRKAWVRGVIENAEDGTVFVEATGLFIEPKWADSLAKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0BME6</accession>
    <name>X0BME6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_12364</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BME6"/>
    <dbReference type="HOGENOM" id="CLU_276082_0_0_1"/>
    <dbReference type="OrthoDB" id="3266505at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF17">
        <property type="entry name" value="SCFA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="548"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="559"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK83345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1154" mass="129277" checksum="4C9238E2729FE0C5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNG7</accession>
    <name>X0BNG7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyketide transferase af380 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNG7"/>
    <dbReference type="HOGENOM" id="CLU_048587_1_1_1"/>
    <dbReference type="OrthoDB" id="2498029at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051411">
        <property type="entry name" value="Polyketide_trans_af380"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751:SF2">
        <property type="entry name" value="DLTD N-TERMINAL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G00380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="27"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="293" mass="32165" checksum="FC4323A6F48A8246" modified="2014-05-14" version="1">MATIRDVDITTYDGLNLKGTFYSVGPKRPCIIMTHGFSGHREHFLPELAAKFNDAGYGALVYDNRCWGESEGLPRCEADPAKQSRDYLDAFNFAAALPDVDPTKIVYWGSSLSGGNAICAASMNKSLAGIISQVPFVSGGSMARITGAPKSVLVSHRIPKSEIPIPIYPNSIEEVQDGTTKAILKDAGAVEFAEEMARRGYSYDKTATLQSMVNTIMHEPTGVIHHISPTPLLMIVADDDVCTYTHLQLEAFEKALHPKTLKVIKGTGHFDLYYGKRFQEVVDVQLEFLKSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNY3</accession>
    <name>X0BNY3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNY3"/>
    <dbReference type="eggNOG" id="ENOG502RKM8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1669471_0_0_1"/>
    <dbReference type="OrthoDB" id="5089136at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="150" mass="16665" checksum="19DFD3B1F3CAE33A" modified="2014-05-14" version="1">MATFPVITVCTVGQLGFWKSSLEEIKETYPLIRANAPRRSPTYLPPPLPVKEKMDEIYRFQWAVDECIVFLRENATNGEKLMVLRVIEWLAAAQRNDTGRIQRAIWTIDPDRFRREMREGHAHGGNGQAIQGPDGGSNVGGDAGGNVGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP41</accession>
    <name>X0BP41_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">beta-glucosidase</fullName>
            <ecNumber evidence="10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_12147</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="10"/>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP41"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_2_0_1"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000003">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF2">
        <property type="entry name" value="BETA-GLUCOSIDASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type III-like" evidence="11">
        <location>
            <begin position="653"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK83626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="751" mass="82132" checksum="2B82F01F6C8F00C0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPQ1</accession>
    <name>X0BPQ1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658434">
        <property type="protein sequence ID" value="EXK80878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPQ1"/>
    <dbReference type="HOGENOM" id="CLU_2049826_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="120" mass="14015" checksum="BD74BDCDED904911" modified="2014-05-14" version="1">MEHRSLTPSERQPFLEDVVKEWILKLNLLKTGDFQTLRDKLPCPTQDQSKYMSQATIDHVHSFREFLVDPEAIVNDKEKIFNYAAGLCETLLLYEILDLLGPEAAMNLYNKWRERATRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPW2</accession>
    <name>X0BPW2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14959</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979337">
        <property type="protein sequence ID" value="EXK80524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPW2"/>
    <dbReference type="eggNOG" id="ENOG502S30A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042179_2_1_1"/>
    <dbReference type="OrthoDB" id="2152029at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF31">
        <property type="entry name" value="STERYL ACETYL HYDROLASE MUG81-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="121"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK80524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="375" mass="41036" checksum="FEA9051A911B7571" modified="2014-05-14" version="1">MKSTTIPRLSLLEKLGLAVKILLVPGTIVGILIRGMPLAIKYKVPLHLWFTCMVGRILLGNFTPRQVQFLSTPTIDVYTAWIKKQRDQGHHTRLNLDIEPLAGPDASIMWIGNRKKASKFVLFLHGGGYVAPPLPGHFTWCWEAYVNGGPGVDKEVAVAVLQYTLAPGGKYPDQLRQASAALNHLLQSGVNPRDLIVGGDSAGGNLTTQLAYHLLHPNPAAPEVKLQSPLAGMFFVSPWLSDRTDTTSFEEYGNVDMLSAGLLQRTSVHSFRSEDLEPKVNGAHPALAVDGDLSWLSDLPAITSALYVTAGRREVFCDAIVEFGKAAQEKCRSIPVQIEVGERECHDFILIENQAEVAGDATERMRKWASGILLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPY6</accession>
    <name>X0BPY6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11894</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPY6"/>
    <dbReference type="eggNOG" id="ENOG502RGY2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_5_2_1"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="113"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="4">
        <location>
            <begin position="439"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK83941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="569" mass="63879" checksum="C0A8BED6AD20266E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR50</accession>
    <name>X0BR50_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR50"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_0_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF272">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="35883" checksum="8B7CDAC59BF3B1DC" modified="2014-05-14" version="1">MTDLYKSVHENPKGPGDARPTAIQIIQDEKLEGKLSSQVVFITGCSSGIGVETAKALYLTGAQLYLTARNLAKAKKALGHLIDDPRVHLLELDLESLDSVRACAATFLSRSSSLNVLICSAGVMTPPEGRTQEGFEIQFGTNHLAHFLLFSLLRPALLAGTTPERASRVVIVASVAHRFGAVHFDNINFEGCYDAMAAYAQSKTANIWMANEIERRYGEQGIHAWSLQPGSVLTDLTRHFSDDQRDGIMSDPYLKSINKFPDQGAATSVWAATAAALEGEGGRYLEDCQIIGPWNPSLPLWGPGYGTHAYDVEQAQMFWEKSRQWVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRE6</accession>
    <name>X0BRE6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_11257</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRE6"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF40">
        <property type="entry name" value="THIAMINE PATHWAY TRANSPORTER THI73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="43"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK84735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="485" mass="52867" checksum="A86208ADCCD7ABE8" modified="2014-05-14" version="1">MTPADNEKIPDIMRPPSVTKGSVQDVISETSLKPITRKVDYHLVPLMLVCYFLQFLDKVLINYANIMGLSENLHFTGNDFSWMATAFFIGFAVAEFPQGVLIQKFPVSKVLGLNVVLWGIVICCSSAAHSFPGMTAARTLLGMFEAVISPALIMITSQWYTRRQATPRTGIWYCGLGIGQTVGGLISYAAQHGSRTSSFQSWRIMFVSVGAFNVMIGLLVLFWMPSSIKDAKFLTEQEQIILQEALDADQGGKSAKIFRRAGIWDALKDIQVWLLFLNTILIVIPSGIITTFSATLIRGFGYDPKQAALLNMPAGVVSVSATLLSTFAILYGFPRWLGLCLLMVPTLIGAGLMSFYSSSQAGSLAGIYLINFDVAPLALIYALVGANVQGYTKKVTTNAIVAVGFSIANIIGPQTFQAKDAPSFIPAKITVFCVCGGSVVVTILTRILYGLRNRKGRVSQDLGQSGEVDPDTMTDRNNPNFFYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSA6</accession>
    <name>X0BSA6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Phosphoribosylaminoimidazole carboxylase</fullName>
            <ecNumber evidence="4 11">4.1.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_14230</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2</text>
            <dbReference type="Rhea" id="RHEA:10792"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.21" evidence="4 11"/>
    <dbReference type="EMBL" id="KI979333">
        <property type="protein sequence ID" value="EXK81369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSA6"/>
    <dbReference type="eggNOG" id="KOG2835">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011534_3_2_1"/>
    <dbReference type="OrthoDB" id="15425at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016301">
        <property type="entry name" value="Ade2_fungi/plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054350">
        <property type="entry name" value="PurT/PurK_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609:SF5">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609">
        <property type="entry name" value="PURINE BIOSYNTHESIS PROTEIN 6/7, PUR6/7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22660">
        <property type="entry name" value="RS_preATP-grasp-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001340">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52255">
        <property type="entry name" value="N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="13">
        <location>
            <begin position="110"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK81369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="594" mass="64839" checksum="2FE685288C047B4B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTL6</accession>
    <name>X0BTL6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658416">
        <property type="protein sequence ID" value="EXK82258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTL6"/>
    <dbReference type="HOGENOM" id="CLU_068089_0_0_1"/>
    <dbReference type="OrthoDB" id="10275431at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="350" mass="40453" checksum="71664AC6D5927265" modified="2014-05-14" version="1">MGTSSCILIYYKGKFCACQIYCQDGGIEGHGAYIFKFLSCPKRTKALKKGLKHTTYISMDQYGSAKWEIGRLLQKGDLLDDIRTWGSFCTEYTSHEPSSLYEAHDHVDACSGPAVLKLISIATAENQVTLVHPAFFSTPTAEKNLEYVHPRFAPESNIHNIDLDELKIEKLGIDHIIMKDFDMDDFDVDDYDYAYMIDLDKSTLKVYEWAFDPVCEYTFAELQRFTEAEFIGHYKKNKGEKNPDNMPKYKVMLAGSLCHNSRVNNSLDLDKRFEVCSAFHQKPTHLVCTSRQFLRRKGIKEIRDAMDNRIPICKYSSSNNEWMNLDKKNNILWHPKYGYMKEWILSNGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTU4</accession>
    <name>X0BTU4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Isopropylmalate dehydrogenase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_10383</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTU4"/>
    <dbReference type="eggNOG" id="KOG0453">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0786">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006714_3_3_1"/>
    <dbReference type="OrthoDB" id="419183at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170034">
        <property type="term" value="P:L-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170038">
        <property type="term" value="P:proteinogenic amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF2">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="7">
        <location>
            <begin position="11"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="841"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1064"/>
            <end position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK85590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1088" mass="118639" checksum="BC273918F7216058" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUE6</accession>
    <name>X0BUE6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription initiation protein SPT3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_10212</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SPT3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUE6"/>
    <dbReference type="eggNOG" id="KOG3902">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038706_1_1_1"/>
    <dbReference type="OrthoDB" id="66982at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22926">
        <property type="entry name" value="HFD_SPT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000023">
        <property type="entry name" value="transcription initiation protein SPT3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003195">
        <property type="entry name" value="TFIID_TAF13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380:SF16">
        <property type="entry name" value="TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02269">
        <property type="entry name" value="TFIID-18kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="97"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="273"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK85770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="320" mass="36705" checksum="2C930AD31DDFACE1" modified="2014-05-14" version="1">MAESRDSKSYKYRQEISQMMYVSGETAEPPVETTSIIEDIVRQQVIELLRNCTELASRRGSKSISINDLIFQIRHDQAKVSRLRTFLSWKDVRKNVKDSDDKGADADIAAGDDPVAAGDNTTDEAAKKNKKAKVGLPWEPSSYYNVEVPEREEEEDEEEEEMNYITLQRLRKADERTKAMTKEEYVTWSEYRQASFTYRKGKRFREWAGFGIVTDSKPSDDIVDILGFLTFEMVQTLTEMALKVKEQEDLVRAQNGGDNVGNAKKRKHEGALFDFPSEGKTPIEPRHVQEGSRRLQQRPKKSRAMLNGTRIAQHTPLNIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUQ4</accession>
    <name>X0BUQ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Catalase</fullName>
            <ecNumber evidence="13">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_10323</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 14">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="13"/>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUQ4"/>
    <dbReference type="eggNOG" id="KOG0047">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010645_2_0_1"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08157">
        <property type="entry name" value="catalase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000001">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF62">
        <property type="entry name" value="CATALASE T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="5 12 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 13" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 13" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="16">
        <location>
            <begin position="35"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="549"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK85915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="578" mass="65482" checksum="887F9D0E7873B5D3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUR5</accession>
    <name>X0BUR5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUR5"/>
    <dbReference type="eggNOG" id="ENOG502RMF4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093917_0_0_1"/>
    <dbReference type="OrthoDB" id="5084929at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="233" mass="26401" checksum="90581A4CB641DCBC" modified="2014-05-14" version="1">MKDRTSDHIHFPQHAHRIPRRSDGVSGYSDLLGRAVLISIINYLADVVDAIEDIKLPKQHKDRTKLKNDKKRMCDTAVRGANTLTALFNSAKGQTKYTDPAPKNLPLYRDEIRGQLLYPLSKAKTSKPSLGKSFTFAPWQQRLTAILSGIEEEVCWWLRLQRPTKTYDKRSTTHSHTTKTYGQRSTASKPYDQYSTRTGKTDQRSSRPKQSKSHSQRGKRSRSPSPSGGCAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV44</accession>
    <name>X0BV44_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_10109</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV44"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF51">
        <property type="entry name" value="ALPHA-GLUCOSIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="56"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK86060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="521" mass="56517" checksum="36C97AE19BBC800B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVU2</accession>
    <name>X0BVU2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVU2"/>
    <dbReference type="eggNOG" id="KOG1576">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_7_0_1"/>
    <dbReference type="OrthoDB" id="5286008at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045290">
        <property type="term" value="F:D-arabinose 1-dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070485">
        <property type="term" value="P:dehydro-D-arabinono-1,4-lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19164">
        <property type="entry name" value="AKR_ARA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044480">
        <property type="entry name" value="Ara2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686:SF1">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="14"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="388" mass="43204" checksum="C067E5A9121CA869" modified="2014-05-14" version="1">MADERKPLSEVIPPLILGTATFNHQYHPDPTHMPYTDIVGRALAHNILGFDTSPYYGPSEILLGDALRKLTPPPPRENYFLITKAGRIAGDEFDYSPAWIRYSVYRSLERLGTSYLDLVYTHDVEFVSPEEVLAAVTELRHLRDQGLVRYVGISGYPVDTLASLAEMILRETGEPLDAVMSYSNFCVQNSQLGNKALLDRFQAAGVDCVPNASMLGMGLLTTRGIDNSPMRAWHPAPEELRDLCARLSSIAQDSGEHLEEVAIRWALENWARVGSRFGTKINPSDTGRLGVSVMGVSSVDELEETWALWTSVVGLVGDEEATQRKVKIESLVREKMWPALGKWKDYAWGSGGPDFVNARRVEDMGVVPRDETAVRWRLIPSAMDTPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVX3</accession>
    <name>X0BVX3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVX3"/>
    <dbReference type="eggNOG" id="ENOG502SB8S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120161_2_0_1"/>
    <dbReference type="OrthoDB" id="78947at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045108">
        <property type="entry name" value="TXNDC17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010357">
        <property type="entry name" value="TXNDC17_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452">
        <property type="entry name" value="42-9-9 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452:SF0">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06110">
        <property type="entry name" value="TXD17-like_Trx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="20"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK86051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="112" mass="12267" checksum="9359FA04D39EB2EF" modified="2014-05-14" version="1">MPLIDANTPPTSTDTHYVVYFASGEPSWCPDCRDALPALNAVFGGASDPTAYIVRVGSREEWRGTPKNKYRNAPYNINGVPTVVKVQNGKEVGRLGDKESQVESSLRKLVDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWH1</accession>
    <name>X0BWH1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">PET8 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_09932</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWH1"/>
    <dbReference type="eggNOG" id="KOG0768">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_3_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000018">
        <property type="entry name" value="S-adenosylmethionine mitochondrial carrier protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="6"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="91"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="192"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK86231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="29663" checksum="C367814EC982A8AC" modified="2014-05-14" version="1">MSANPPTFQSALLAGALAGTTVDLSLFPLDTLKTRLQSSAGFFPSGGFNGIYRGIGSALVGSAPGAAFFFCTYEGVKGFLADKDNTSAPGWKAPLTHMAAASAGEVAACAVRVPTEVVKQRAQAGHHGGSSAAALRAILSRYSSHGFVPMWRELYRGWGITVFREVPFTVIQFPLWEAMKSWGRRRRGGREVTGAESALYGSMAGGLSAALTTPLDVLKTRVMLSKESVSVSDIFGRILREEGSRAFFAGVAPRVTWISIGGAIFLGSYQWAINTMNGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXF9</accession>
    <name>X0BXF9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine/threonine-protein kinase PRP4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_09625</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXF9"/>
    <dbReference type="eggNOG" id="KOG0272">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_20_1"/>
    <dbReference type="OrthoDB" id="540662at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000698">
        <property type="entry name" value="Putative pre-mRNA splicing factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00500">
        <property type="entry name" value="SFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="5">
        <location>
            <begin position="63"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="256"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="285"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="327"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="373"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="480"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK86875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="519" mass="57230" checksum="01852777E9A67660" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXI5</accession>
    <name>X0BXI5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_09639</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXI5"/>
    <dbReference type="eggNOG" id="KOG3989">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081915_0_0_1"/>
    <dbReference type="OrthoDB" id="1898221at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006838">
        <property type="entry name" value="ADTRP_AIG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10989">
        <property type="entry name" value="ANDROGEN-INDUCED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10989:SF16">
        <property type="entry name" value="AT02829P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04750">
        <property type="entry name" value="Far-17a_AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK86900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="235" mass="26532" checksum="3A2A0901C7A7149C" modified="2014-05-14" version="1">MAPRHPLQRLTSPSRDVSLLLHIIGIASFSYNFHFLTVWDTPIARSYGWHMQFLTIIGLSASLIAFVLGALADITLSPTLFQAKNAVAVLATPLEVVISILYWGLRLIDPKLLMPDDFYMHIIPDMGFHLAPAVLLSLDLVLLSPPWAIPAYGVMAISTVIAFAYWYWVELCFSHNGWYPYPLFELLSTTQRVMLFTFSAGLVTVSSSFLKWVYGRVNGYEKAEREAHKPLKKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYI4</accession>
    <name>X0BYI4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980036">
        <property type="protein sequence ID" value="EXK75602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYI4"/>
    <dbReference type="HOGENOM" id="CLU_3392422_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3584" checksum="1AE507DA3ED71B8D" modified="2014-05-14" version="1">MPYCCEELDCDVICPRRCIPGILDIVLSCPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZD6</accession>
    <name>X0BZD6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_11836</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZD6"/>
    <dbReference type="eggNOG" id="KOG3855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_2_2_1"/>
    <dbReference type="OrthoDB" id="2096480at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="5"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK83879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="415" mass="45479" checksum="9AF5B6C320F52EEE" modified="2014-05-14" version="1">MTNQSVVVVGAGPVGLFTALILAQNGIKVTVIEADEGISRSPRAAVQLPCVNLEFAKAGIIEEVFEYGCKSKHGYSWRDGYDTTKVLADFTPPPSDNPNLCAAMIGQDVLSQIFLKHLINTGNAEIIFNHAFTRVEDHGDSVTVHARRVLDDQELSFNCRYVVGADGGKSSVRKCMGLSLEGYTWPDIRLIAVNILYDLEKLGWKHGNFIVHPEDWAIVVKRGPKNLWRVATSVPFAQGADGEPITDKAVFPVIKERLARILPGNTDEIIYLQTAPYTIHQRCVSKYRVGNIMLAGDAAHLNNPVGGLGLTTGLLDAAHLGKALTQVLNENAPETVLDEYAKARRDVYKNVTDPLSTANLLRLKSTAPEDVATREAFFKMMNDPNEKGQLFAHMAKEMGLSTTLNMKDLGPMPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZT6</accession>
    <name>X0BZT6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_11480</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZT6"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="5399138at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="9"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK84443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="475" mass="51176" checksum="37CE384CEB0CBF55" modified="2014-05-14" version="1">MKVPLYASAGVATSCVAFLFGMDTGSIGPITTMASFKDTFGDFSATIHGVIVSTILIPGALTALIAGALAHRFGQVRLIAIGSIIFGVGAAIECGAPYLGVFILGRLIKGMGEGLFLSNVYVQVSEMSPSRVRGIMTALPQVGITSGIVTGYFTCYGTSRLGSSSITWRLPLAIVAFLGVLLSMVAFIVPPSPRWLLSKGRTDEARTVCRQLGIDEAEEKELLAQMQDTPGGLDGETSLWHEIRHTFRDFRCAFSAPYRGRTAFACFLMGMQQLSGIDGVLYYAPILFTKAGLSGEKASFLASGVSAIVLLVATFPATIFADQWGRRMQSILGGVLIVGLMVIMGSLYASGQVHPDHGAGRWVVIVCIYLFAISFNLTWAIGFRTWVVESMPRRTRSSASSLAQSSNWTVNYIVALVTPMLLDESSFGAYYLFAGCSLATTVMVILFMGETKGYSLEEIEKRHGETREKKIPFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZY3</accession>
    <name>X0BZY3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_19138</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979603">
        <property type="protein sequence ID" value="EXK76102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZY3"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000188">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF9">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="41"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK76102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="415" mass="46088" checksum="BEC787A2914557FB" modified="2014-05-14" version="1">MASDDKHKHHESLAFDQENGSQIVVDAAAERSYLRKMDAWLLSYLSVMYFFNAVDRSNLGNAETDGMSKDLNFKGEEFSLLILLFYVPNGLCDLPLNLLLKKFSGRIMLPSLMVGWGSMALLQAACKNFAGMLAIRLLLGAFEAGFFAGAVFYLTLFYQRGELGFRIAIFFGSALLASAFSGLISFGVFQIKVSHIHGWMWLFLIEGTMTVLLGILAFWWLPADPQSAWFLTKEEKHVARQRALRDGSGVIGEDFNLKECFKSWNSWRFAVWCVISLTYPVAFSTTSNFLPLIIRRLGYNTVITNLLTMPPNVAGFLVLLAVTWSSDRNRERTLHIVGSLSTSLVGLLILAIIDAEAHIGVAYFACFMLCAGAYIPSCLVHSWHNNNNLSENSRAATTGLLVAGLPSDQSNQIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1A5</accession>
    <name>X0C1A5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1A5"/>
    <dbReference type="eggNOG" id="ENOG502S0B1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019613_1_1_1"/>
    <dbReference type="OrthoDB" id="27483at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF14">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT FE(2+) 2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="154"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="493" mass="54542" checksum="80951A395E00B211" modified="2014-05-14" version="1">MESPVVTSQPTGDSSSLKGLLSAVSSALDKRAGKDIFAIGGSVGDDGGPSHAASNSITIRWDNKEQVHSRTLKLPLGDDTVTQDAFNTLVADCQPATFGVGSQEVLDEEYRKAGKMNTEDFCTDFNPYEHGIVDTINQVLAQASVTDARGLGVKAELYKLNVYSGPSGKFKPHVDTPRSDRQMGSLVVSLPIEHKGGQLAVRHGGREIVFDWAPKSADTIQWAAFFSDCEHEVLQVTEGHRVTLTYNLFWINYGPASMSDHLRALDQESLHFFDALEKLLENKHIIKEGLVGFSCTHAYPHTSKSSTNNLHHMLKGIDMVVYQALKRILGTAEVAALVDDEKYRHYEQESIPEMIEWKKDHRLKYNPHLPEPKITQAEQDVLDDKLAIGTAPKPALVFRHSYEKRLDPAEVGLQHEYSRKTRGKFYPRRDVTWLNGPPDSEVSKELAVAFITYGNEPGIDAYYTSAVIVAKVNTSPQADESTQSESASDATED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1J5</accession>
    <name>X0C1J5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1J5"/>
    <dbReference type="HOGENOM" id="CLU_2573996_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="81" mass="9563" checksum="FDDDF930F6CFEDF8" modified="2014-05-14" version="1">MQDKNWDNAGEEDRRVRARTMVKHILQNEKWTKSEYAWEADAWKDVFGMMRDDPVLAVDKHLNRPIRAALNSFLGADIYIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1R2</accession>
    <name>X0C1R2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine N-methyltransferase 2</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_08634</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1R2"/>
    <dbReference type="eggNOG" id="KOG1709">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033831_0_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019702">
        <property type="term" value="F:protein arginine N5-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000135">
        <property type="entry name" value="Arginine N-methyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017408">
        <property type="entry name" value="Arginine_N-MeTrfase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051038">
        <property type="entry name" value="RMT2/GAMT_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026480">
        <property type="entry name" value="RMT2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379:SF1">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038148">
        <property type="entry name" value="Arginine_N-mtfrase-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51559">
        <property type="entry name" value="SAM_RMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RMT2" evidence="10">
        <location>
            <begin position="194"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="149"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK88350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="431" mass="47972" checksum="47B4025D0144E5DD" modified="2014-05-14" version="1">MPLIMAPKIDDSMPARISSDCPDEIREVLYHAWGHDRSGLQKLLKTTGKANAQDPKTGETPLHAAIRACGPASGDDDDQEEDGSVEEAKEIVHDLFLRGAIWNDVDSNNETPGCLALRLGRKPLYNLCVEAGVRAELLFALMGDYEALSSGSDDGDEEMEAEQDDEEAPQLVSAEDTAPPPEEPKFIPPDAQEKQVTSEEYLNSKLVYDDAKLVDSDLNGVMMAWETDIMRRSVAALIPDSAPGKRILNIGFGMGIVDGMFADLKPSRHHIIEAHPSVLEHLSKDESKFGPSWENSGPEEGAFKVHKGKWQDIVPKLLEDGEVYDAIYFDTFGEDYSQLRHFFSECIIGIMDQDGKFSFFNGLGADRKICYDVYTKVVEMQCADAGLDVEWEESDVDMSGLEKAGEGEWEGVRRRYWTLDKYRLPICTFMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1U2</accession>
    <name>X0C1U2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Calnexin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_08643</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the calreticulin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1U2"/>
    <dbReference type="SMR" id="X0C1U2"/>
    <dbReference type="eggNOG" id="KOG0675">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018224_1_2_1"/>
    <dbReference type="OrthoDB" id="1938156at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.250.10:FF:000001">
        <property type="entry name" value="Calnexin homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000011">
        <property type="entry name" value="Probable calnexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.250.10">
        <property type="entry name" value="Calreticulin/calnexin, P domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001580">
        <property type="entry name" value="Calret/calnex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018124">
        <property type="entry name" value="Calret/calnex_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009033">
        <property type="entry name" value="Calreticulin/calnexin_P_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073:SF1">
        <property type="entry name" value="CALNEXIN 14D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073">
        <property type="entry name" value="CALRETICULIN AND CALNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00262">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00626">
        <property type="entry name" value="CALRETICULIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63887">
        <property type="entry name" value="P-domain of calnexin/calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00803">
        <property type="entry name" value="CALRETICULIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00804">
        <property type="entry name" value="CALRETICULIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00805">
        <property type="entry name" value="CALRETICULIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="237"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="524"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="525"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="138"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601580-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK88380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="561" mass="62520" checksum="B377753FF71F2E50" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2D8</accession>
    <name>X0C2D8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_10683</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2D8"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033229">
        <property type="term" value="F:cysteine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000483">
        <property type="entry name" value="Related to allantoate permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF63">
        <property type="entry name" value="HIGH AFFINITY CYSTEINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="448"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="58"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK85323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="516" mass="58280" checksum="41BA7F778885F2D7" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C480</accession>
    <name>X0C480_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_07871</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Efflux pump involved in export of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties. Constitutes a self-protecting mechanism of the fungus against critical levels of FSA within the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C480"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_11_2_1"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF186">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="388"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="12">
        <location>
            <begin position="55"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="494"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00054466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK89175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="534" mass="58494" checksum="659984FC43960E3D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C486</accession>
    <name>X0C486_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Arsenical-resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_17724</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658592">
        <property type="protein sequence ID" value="EXK77577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C486"/>
    <dbReference type="HOGENOM" id="CLU_022869_0_0_1"/>
    <dbReference type="OrthoDB" id="187348at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015104">
        <property type="term" value="F:antimonite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000009">
        <property type="entry name" value="Arsenite transporter, ACR3 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057:SF1">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="ARSENITE EFFLUX TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0059">Arsenical resistance</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK77577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="394" mass="43300" checksum="6B7CE8DBC2C10325" modified="2014-05-14" version="1">MEMKNGLSSHEPKPSPPRAGPDNESIGQADQDPEATAATMSHDEQPKQHLSAFKGLGLLDRFLALWIFLAMAIGIILGNFVPETGPALQKGKFVGVSVPIAVGLLVMMYPILCKVRYESLHELFSHREMWKQICFSIFVNWIVAPFLMLALAWAFLPDKPELRTGLILVGLGRCIAMVLIWNGLAGGNDEYCAILVAINSILQMVLFAPMAVFFIRIISHESGTIDISYSVVATSVAVFLGIPLGAAIVTRIVLRKVAGPDWYQQTFLKFLAPWSLIGLLYTILVLFASQGRQVAHQIVSVVRVAAPLIVYFVLIFFVTLWISRLLGFRLSMVVTQSFTAASNNFELAIAVAVATFGPNSDQALASTVGPLIEVPVLVGLVYAVRWMANRWDWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4H5</accession>
    <name>X0C4H5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4H5"/>
    <dbReference type="eggNOG" id="KOG2451">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_5_4_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07103">
        <property type="entry name" value="ALDH_F5_SSADH_GabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000023">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF7">
        <property type="entry name" value="SUCCINATE SEMIALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK86093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="499" mass="54231" checksum="40C12DD8B22A83D1" modified="2014-05-14" version="1">MTRNLPFKLDDPSLLHEESLLDGQWVQSQSGERFGVEDPGSGHIWAASPTNKVSDVDRYVESSHAAFQSYRHVNPRQRAKILLKWHELITNARQDIAKIVVFETGKPMAEAVGEVDYALGFAWWFAGEAERIRGSIAQPAISDRRTFVIKQPIGVCVALVPWNFPVAMIIRKVSAALAAGCTMIVKPSPETPFSVMALADLALRAGLPPGVLNVISTDNANTPSVSETLCKHPLVHKVTFTGSTSVGSIIARHCSGGLKKVTMELGGNCPFIIFDDGDLEQAVAALMILKWRTAGQACTHANRVYVQSGVYDKFAQMMLEATSKIRLGHGAESCSTMGPLTTARGVDKVKKHVQDAVSRGGKILCGGKQPENLNGYFFEPTIISDMTSDMLTTQEEVFGPVLGLYKFETEEEVVQKANDTSMGLASYFFTKDVSRTWRLLESLEAGMIGMNTGNASCAESPFGGIKMSGYGKEAGKDVAIEEYLIQKTGTLTVEDLSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C534</accession>
    <name>X0C534_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L33-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C534"/>
    <dbReference type="eggNOG" id="KOG0887">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100745_1_0_1"/>
    <dbReference type="OrthoDB" id="1166329at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.190:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.190">
        <property type="entry name" value="translation elongation factor selb, chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00573">
        <property type="entry name" value="Ribosomal_eL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001780">
        <property type="entry name" value="Ribosomal_eL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018266">
        <property type="entry name" value="Ribosomal_eL33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038661">
        <property type="entry name" value="Ribosomal_eL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10902">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01247">
        <property type="entry name" value="Ribosomal_L35Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01105">
        <property type="entry name" value="RIBOSOMAL_L35AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK89236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="109" mass="12187" checksum="F776BF4260D00F14" modified="2014-05-14" version="1">MPSEAGHRLYVKGRHLSYQRSRHTTRPATSLIKIEGVDDTNAANFYLGKKVAFVYRGQKEIRGTKIRVIWGKVTRPHGNSGVVRAKFTSPLPTKSFGASVRVMLYPSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C564</accession>
    <name>X0C564_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C564"/>
    <dbReference type="eggNOG" id="ENOG502RMC7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043052_0_0_1"/>
    <dbReference type="OrthoDB" id="5210863at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="57133" checksum="BC3269CCE6CE000D" modified="2014-05-14" version="1">MATFVETINILRFEIIPQLSIRDQLHLCQTSKDLHTATVSVLYRDITITHDVEVPNDPPLSAGKLRRLERLRAARRKRLPWGVGFLFAILSRPALRSHVKSLRFRIENYVHDEHFRDTGLLKPLNIHPLDNEKARQMILDGIDDLSFSETEKLSAAFTGRDFDLILSLTIAACTEIQSLTIDLGYFLYSHKWLLELFKNSLSPQTKSHSLQNVTHFEVANPRGWLGYQQLPRGIHPLSFYLPKVRTLSLESFASHRKGENSALADTNPFWPLSSAPQATFLTTLHLDHCSSNAHNIAAMLAQTPNLKTLFYACYLPAFECDFDVDELRRGLEYVRNSLSKLTLNLIIMQRGLIDFSDHEWPLTHGRIDDLREFLSLTDLEIPLTFLHGHTAPEHWQPLADLLPPNLISLTVKDELMDDYTTFQDLYTETAIRDMMQTFLSYGSRSFTLSLRHVYFYRYPAIWDYKNLSKGPEKEYYENWKPVDDKYGSRWAFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6U7</accession>
    <name>X0C6U7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_09288</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="5"/>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6U7"/>
    <dbReference type="HOGENOM" id="CLU_065200_6_1_1"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK86918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="239" mass="26332" checksum="E8EA1560E94CDEE8" modified="2014-05-14" version="1">MALQLSLSQASLAAAILGSTYGTYLALSPPNPSEHAAPSTGDSVRWLFLTSKHTTKVVLAPLGLLSLHTASLALRYPNIPPPLVHHGIENGLNPDLITWSAATTIPLALIFCAGVPLRLVPYASLGKNFTFALKEPDRLKTTGIYQYLQHPSYTGLAILMIFNVALLGRLDGVLSCWIPPNVYETFCSWAIRLLPFTISGVMFGIWTRVSEEEKMLKRAFGKEWESWHARTARFVPFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C948</accession>
    <name>X0C948_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">5'-nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_09183</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C948"/>
    <dbReference type="eggNOG" id="KOG4419">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005854_7_1_1"/>
    <dbReference type="OrthoDB" id="7722975at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07409">
        <property type="entry name" value="MPP_CD73_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000020">
        <property type="entry name" value="NT5E isoform 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF24">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152134" evidence="6">
        <location>
            <begin position="19"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="8">
        <location>
            <begin position="40"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="9">
        <location>
            <begin position="340"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="539"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK87369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="588" mass="64276" checksum="C8B5886CB59ABDB2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9Q4</accession>
    <name>X0C9Q4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658472">
        <property type="protein sequence ID" value="EXK79417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9Q4"/>
    <dbReference type="HOGENOM" id="CLU_918423_0_0_1"/>
    <dbReference type="OrthoDB" id="10374827at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="304" mass="34541" checksum="68312E8F7FA73307" modified="2014-05-14" version="1">MFLSQPGDTPSEARGHLTEPDDTPTNNADDLSWCQLNFIAQSFSIFISTEEQPSDLGCFMRDLEDRGPQGFLDYIRGRLHKHTNTSSRQDSGDNYEENLTEELKWFKDILTWKNNRTSPVAFTDDKSCDVNDTTLFHRFEVMRQPDVDWRGIPPGDIEIALVLILSYLLGERGEYPELSSGNAIRRALLTTLDKCQNEGRILEETNPSTHRIPPFNVPHAARIGPGLTHLLPPPPPPLLPQPHMASTQNISKASVTFQHSWNIENSMCKSSGSFQFRLPSLPEESWFKVAMIFLLILHSFKLYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBD6</accession>
    <name>X0CBD6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBD6"/>
    <dbReference type="eggNOG" id="ENOG502SGJ9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073635_0_0_1"/>
    <dbReference type="OrthoDB" id="5414285at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="223" mass="23749" checksum="2541283AAF583280" modified="2014-05-14" version="1">MVSTAGGIVIAIIVLLVAGAVGWVVFTQLRARRLGLPPPSLASYLPWHKEDSGYGIQPAPSGIAGWFNDKIRKFKNRNNRSAAGAYEQSGGARGRRGFGPLDPDEAWDSRVGNEADQYGYYEEDVGGRGRDTGYGGGYNMNLAATPGLSGGRGFDEEEDRGRRASRSPASGPGGRNPFDDDAGSSLRGVSPRPIDTGVAKPKNRSGSAESSPTERRSVFRENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBJ1</accession>
    <name>X0CBJ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CNH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06271</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBJ1"/>
    <dbReference type="eggNOG" id="KOG2063">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008225_0_0_1"/>
    <dbReference type="OrthoDB" id="5325112at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF27">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CNH" evidence="6">
        <location>
            <begin position="44"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="242"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="507"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK91516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1193" mass="132128" checksum="8CDA87CB7F92F7C8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCP7</accession>
    <name>X0CCP7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endo-1,3(4)-beta-glucanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCP7"/>
    <dbReference type="eggNOG" id="ENOG502S1W9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019533_3_1_1"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02182">
        <property type="entry name" value="GH16_Strep_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936319" evidence="1">
        <location>
            <begin position="18"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="28"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="281" mass="30834" checksum="5D16FBFB9BEF3035" modified="2014-05-14" version="1">MLNFIPIIAGLASLVSATSAPTRPDLKLIWKDEFTGCQGCSPKTNNWNTALNINSNNELQVYSTSNKNIQLSGGDTLQLVPWKDGKGEWTSGRLESKKAFHADKNKALRVEASIRMGDSARKQGIWPAFWMLGDALRHGTGWPLCGEIDIFERVNGDLTGFGTVHCGHEGGGPCNEPEGLGQRVTIPDNEFHAWSVVIDRRASSWQDEKITWLLDGEPFHSITGKTLNDEGTWATLAHSPMYILLNVAVGGTWPGNPNKATEAGYKNMMEVAYVAVYETTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD49</accession>
    <name>X0CD49_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NIPA-like protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD49"/>
    <dbReference type="eggNOG" id="KOG2922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012349_2_1_1"/>
    <dbReference type="OrthoDB" id="165382at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF65">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="422"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="473"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="621"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="700"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="656"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="712"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK92091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="723" mass="77958" checksum="C71CE9A252217BE9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD51</accession>
    <name>X0CD51_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD51"/>
    <dbReference type="HOGENOM" id="CLU_005132_0_0_1"/>
    <dbReference type="OrthoDB" id="4738706at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057218">
        <property type="entry name" value="DUF7896"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42031">
        <property type="entry name" value="KEY LIME PATHOGENICITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42031:SF1">
        <property type="entry name" value="KEY LIME PATHOGENICITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25438">
        <property type="entry name" value="DUF7896"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="776"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="957"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="984"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="1016"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="1070"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="942"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="698"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="951"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1115" mass="124107" checksum="348856D01A703B6D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDQ9</accession>
    <name>X0CDQ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658437">
        <property type="protein sequence ID" value="EXK80757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDQ9"/>
    <dbReference type="HOGENOM" id="CLU_042091_1_0_1"/>
    <dbReference type="OrthoDB" id="3432781at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025213">
        <property type="entry name" value="Sim4_Fta2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13095">
        <property type="entry name" value="FTA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="30518" checksum="E76DCADAF2B9F457" modified="2014-05-14" version="1">MSPIPEQLPPCEGPKLKKFPYHNSTIQWLERLDENREDDDVTSSQGYVFKARIGSREYAVKVFKFCDPMSTEYAWGPQLGEDTSLDTAAYYTDPFYAECRAYGQIREAIEKSILKKDVAVPCHGFFFLKTKDQETLQNRNIDLGLDLVDMNYQRSAIGGRRARAIVKDLASSNSVITSTSTRKILSKVDLMNKAGIYNMDIRIGNFCDGQLVDFGSSWTEPHALLASLSREAAAESKLADRVMFNHMVENAGLKNCGKVHSMRLRSHIRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFE6</accession>
    <name>X0CFE6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Crossover junction endonuclease MUS81</fullName>
            <ecNumber evidence="14">3.1.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_07420</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Interacts with EME1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the XPF family.</text>
    </comment>
    <dbReference type="EC" id="3.1.22.-" evidence="14"/>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFE6"/>
    <dbReference type="eggNOG" id="KOG2379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014329_1_1_1"/>
    <dbReference type="OrthoDB" id="5963188at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048476">
        <property type="term" value="C:Holliday junction resolvase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048257">
        <property type="term" value="F:3'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21036">
        <property type="entry name" value="WH_MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20074">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000307">
        <property type="entry name" value="Crossover junction endonuclease MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000003">
        <property type="entry name" value="Crossover junction endonuclease MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.110:FF:000001">
        <property type="entry name" value="Putative Crossover junction endonuclease MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033309">
        <property type="entry name" value="Mus81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047417">
        <property type="entry name" value="WHD_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047416">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451">
        <property type="entry name" value="CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451:SF0">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21136">
        <property type="entry name" value="WHD_MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="11 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 14 17" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0469">Meiosis</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="16">
        <location>
            <begin position="290"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="79"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="215"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK89963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="581" mass="65574" checksum="5103E16A226E4172" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFN9</accession>
    <name>X0CFN9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFN9"/>
    <dbReference type="HOGENOM" id="CLU_1165848_0_0_1"/>
    <dbReference type="OrthoDB" id="5275938at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="31198" checksum="15D4BD050AB298E8" modified="2014-05-14" version="1">MPIQTPNPESSTTRPESSQTTPDQEGVSLVDGTPECEQDIVSDGNLVLIVGAGEKRLRITVQAVRVCSRVLAGILDQHNITGADNTGRVYELRLPNDDATAARNAFGSIYPGNPHTDDLRPAEIYDVVMFARKYEMIPEFKKVAPNWFRPRYCSSRFHPVHMFFGLEDCWHLMIAAYYMFLDDPDELPDLRFAFSKLSERLVRDENPYYNARLREPVPDGHGIEVDIYCSIREARRDYGRAMDQHSQFRCMGGAAPCAEPIFRWGYGSFYLCRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFR6</accession>
    <name>X0CFR6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14109</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFR6"/>
    <dbReference type="HOGENOM" id="CLU_036369_3_1_1"/>
    <dbReference type="OrthoDB" id="3647at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051999">
        <property type="term" value="P:mannosyl-inositol phosphorylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051706">
        <property type="entry name" value="Glycosyltransferase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385:SF15">
        <property type="entry name" value="INOSITOL PHOSPHOCERAMIDE MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385">
        <property type="entry name" value="MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="358" mass="41530" checksum="3814DB651A2621D5" modified="2014-05-14" version="1">MALQNIIQHLRARFGKYERLYDEEHFESESPSYKRCVPKRFGFPRFRKLTVYLILINLIILGLLIHSIHPLITLLVRNDELFAINFSVDHAAHPEAFQRPDGRKIPRILHQTAPNSSIPEIWATSQQSCKEAYSDFEYKLWTDDGAREFLKEEFPWYLDTWDNYPFPIQRADAIRYFVLYHFGGIYMDMDTYCNSSFPIDQIESLPGNDHALFKSTLPTGITNDFLISTAKHPAFASAVSRLASFHQTTRLWARLQPYAAIMLSTGPLFLTLAVQQYLLGQPILPSPTIHIMDPEMLLPYMTDFETATWHQSDAQVLKWLGDRPWTWFSLGFIGVIAGVYTFNCVLSRTFTTLYRKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGU4</accession>
    <name>X0CGU4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGU4"/>
    <dbReference type="HOGENOM" id="CLU_880112_0_0_1"/>
    <dbReference type="OrthoDB" id="5076551at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK90473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="316" mass="35959" checksum="68B7CF9A4284999E" modified="2014-05-14" version="1">MQDSFIARIKWHTQSSLGLPSSEPSGSGDGGKPVQIFTRIREKTREWHKLRRAGGKVQNLQAQYLAEQAKIQGTVSPPITISRPAMELQRLPPVPAELPGDNTDIYSRERLERSQSAHQHEAPGSRPVPVTDDSHPPGESGKFILVSDPVLDNAKGSGHQHRDTPHAQRNGTVEYERDLKILLDESCVPQPLIGPSHVVQDDIEILRLETRIQTIRRNCEQLTEIRTELEQQILVAKEFAFKLYCQTHEWGCWSPILQDPVPLLQVLKGLQTTMLWLQARIQWYERKYPGLREQYNTHTGLQNKTSDVVRLEDSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIG3</accession>
    <name>X0CIG3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIG3"/>
    <dbReference type="HOGENOM" id="CLU_2061563_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="119" mass="12924" checksum="D66A0E78DBD262F5" modified="2014-05-14" version="1">MLSAWNRQLVQPCFSSKLTSCPGQTIGLRIYLLDCATFVARISRSIAQSSGDVRGVSIIRVIVHRAAKYLNYMSQLLLATKVAGNLPSTQSLASSGVKPWLKTVGDDLSSELSRSPGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJH6</accession>
    <name>X0CJH6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_06543</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK90994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJH6"/>
    <dbReference type="HOGENOM" id="CLU_008471_0_0_1"/>
    <dbReference type="OrthoDB" id="5297881at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="644"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="842"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK90994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="900" mass="97469" checksum="70E3ACDEA5F177BF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJQ1</accession>
    <name>X0CJQ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_04494</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="11"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJQ1"/>
    <dbReference type="eggNOG" id="KOG1389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_1_1_1"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF8">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14 17" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="15">
        <location>
            <begin position="34"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="16">
        <location>
            <begin position="296"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="13">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK94411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="418" mass="43492" checksum="CA077E3768216AC2" modified="2014-05-14" version="1">MGVTDRIIQIGGQISGNPTAGGREKILQKNPDDIVVTAACRSAFTKGGRGGFKDTPAADLMAGVLKAILDRSKINPALVEDLCVGTVLAPGGGATEMRAASLVAGFPESIAVRTLNRQCSSGLQATVDVANQIKTGMIDIGIGAGVESMSLNYGPGAVSEFSEAFENHPEAANCKVPMGVLSEQMAKDLNVTRAAQDAFAASSYQKAVKAQKAGLFDEEIAPLKVKFEDKEGNTKEITVSKDDGVRDGITAESLGKIRPAFAKDGSIHAGNASQISDGAAAVLLMKRSTAEKLGQKILGKYVCASIVGVKPLLMGQGPWKAIPKALDLAGISKDDVDIWEINEAFASQCLWCANELGIPQEKINPKGGAIAFGHPLGCTGARQVSTLLYELKRTGQKVGATSMCVGTGMGMAAIWVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKE1</accession>
    <name>X0CKE1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKE1"/>
    <dbReference type="HOGENOM" id="CLU_158103_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="93" mass="9600" checksum="A382BB0DC55729BE" modified="2014-05-14" version="1">MCIPLFRKKKHDRVYDYHPQPAMGYSKKYGYNNYGYYNGGKKSRKHGRHYASAAGDLAGAWADYSGGGHHGGGHCDGGGGGGGADGGGGGGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKE9</accession>
    <name>X0CKE9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_06431</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKE9"/>
    <dbReference type="HOGENOM" id="CLU_044876_6_0_1"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF6">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G00280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="2"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK91758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="324" mass="35694" checksum="125551C5FFC0DA5B" modified="2014-05-14" version="1">MKVAILGATGETGASILNGLLNSTEPRYEITALVRPSSLKRPEVLALHEKGIKVVPADLSAPEDELSRLLHGIDTVISAISATGLLMQIPLINAAQAAGVKRFLPCCFATVMPPEGILKLRDTKEHVINHIKKVKLPYTIIDIGYWYQLMLPRLPSGRIDYALPLTLGGIAGDGNTPCAFTDLQDIGRWVARIIADPRTLNKMVFAYNAVLTMNQVYDMLEEASGEKIDRNYVSEATMKAGVVRAETDTPPADSFNYFEVVKYQYFNSLGLRGDNTPEYARYLGYVDATELFPDMKVTTPEAYCQEILSGKAITIYQRLMSAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLW8</accession>
    <name>X0CLW8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLW8"/>
    <dbReference type="HOGENOM" id="CLU_2250222_0_0_1"/>
    <dbReference type="OrthoDB" id="5011924at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="127" mass="14123" checksum="D92A76D752E9B11D" modified="2014-05-14" version="1">MAIGILYTQKPGGPCKTLPESSIMDDQGEGNACQLYIPRICSPIFLRLECHGDISSVVSFDIARPSLTRVSSNRADPSRPSSLPIQIVDGPHGYPIDIRLFRAQDYKDDINRDHALMYDIILLDTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPW8</accession>
    <name>X0CPW8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glomerulosclerosis protein Mpv17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_05486</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPW8"/>
    <dbReference type="eggNOG" id="KOG1944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049109_10_2_1"/>
    <dbReference type="OrthoDB" id="430207at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF113">
        <property type="entry name" value="MEMBRANE PROTEIN, MPV17_PMP22 FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G13840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK93363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="27796" checksum="7EC8C5A4AC9FE434" modified="2014-05-14" version="1">MTILILRPAFKHPLRHLQRRFQTSPPKKDPIPVPATVAPLPLWQRLGPLTTAVQAYARAQNKSPYKTQVATAVVIYIAGDLSAQYVSGNEYDPVRTLRNAVIGCVAAIPNYKWFMFLSHNFNYSSRLLSLATKVTVGQVVFTPIFNTYFFGAQALLSGCDIPGTIERVKDTVPTSIINSCKLWPMVTAFSFSFLSIGWRPLFHGVVAVGWQTYLSFLNRMAEVKERERHESEGKMEVGDRVGYAVAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ75</accession>
    <name>X0CQ75_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ75"/>
    <dbReference type="HOGENOM" id="CLU_2291806_0_0_1"/>
    <dbReference type="OrthoDB" id="10677272at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="101" mass="11264" checksum="F127E4905484D8D8" modified="2014-05-14" version="1">MKESVVAREPRLAAFVVELVKPMICYKKRACNVGMECYVMKRSESKQCYPSCSCSETGQQGLMNRVLGQDGKTGRGQEQDKVAKASQKRESEAWRRKVGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQY9</accession>
    <name>X0CQY9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02268</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQY9"/>
    <dbReference type="eggNOG" id="ENOG502RNV0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075094_0_0_1"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF15">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="208"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK96860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="33400" checksum="1620083EAFC5B93D" modified="2014-05-14" version="1">MDKCVKKIYSPRHDSLLPVWNAAIEIRRELHQFAEQQLKDMKFGLVGDPSTGELGVCQAMVSTMYHHTLLLTFRPFLILRAKLNHDRAAATSAENLQMPPPWLDSACEYCLEAARNSVGFLTGSCATNILCRDIKYHGFFMEGACYALAFDMLQEKKTAHRNLPWIHSGLRCLRSMMGSAGVNAGQLPITIASIEQMVRSAGFELKDPVDTNQQKQPPQSTLPGSPAPVSVAGGMRSEPAFTFPSMPFGFDVTGQMNGSSSSPAGAASEDMADFTAADVGWDIDFGTMNMEAFLSLDSAEAFNFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRB6</accession>
    <name>X0CRB6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02353</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRB6"/>
    <dbReference type="eggNOG" id="KOG1547">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017718_7_1_1"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032161">
        <property type="term" value="C:cleavage apparatus septin structure"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005940">
        <property type="term" value="C:septin ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000921">
        <property type="term" value="P:septin ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043934">
        <property type="term" value="P:sporulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000260">
        <property type="entry name" value="Cell division control 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="7">
        <location>
            <begin position="31"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="309"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK96990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="338" mass="38660" checksum="26DA2134098E3276" modified="2014-05-14" version="1">MAAAPPNTIYPQSHVGFDSITSQIEKKLLKRGFQFNVICVGQTGMGKSTLINTIFASHLIDSKGRFQPDEPIRQTTEIQAVSHNIEENGVRLRLNIVDTPGYGDLVNNDRCWDPIVKYIKDQHSAYLRKELTAQRERYIQDTRIHCCLFFIQPSGHSLKPIDIVVLKKLSDVVNVVPVIAKADTLTVEERQEFKERIKEEFAFHNLKMYPYDNEEFDDEERALNGQIKNLVPFAVVGSEKSIIVNGKQVRGRQNRWGVINVEDETHCEFVYLRDFLLRTHLQDLIETTSQIHYETFRAKQLLALKESSAHGGASSRPISPAADRELSRNSQRMTMNGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRH3</accession>
    <name>X0CRH3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_05073</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRH3"/>
    <dbReference type="eggNOG" id="ENOG502S9HG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109915_0_1_1"/>
    <dbReference type="OrthoDB" id="2117453at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451">
        <property type="entry name" value="MARVEL DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF5">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="8"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK93913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="157" mass="17028" checksum="E2352C17192E158E" modified="2014-05-14" version="1">MSRIAFLSLRALQLALSIASIGLSAYVVNDYNQRSRNSAPSPFTYLMVSSIFSILSVAYLSLTPLFVPRIYHQYAAVVVESVNAALYFAGFIAIAVFIGSLIMCEGTVCSCARADAVVAAGQFTAWITTTAFTAKDLFKKAFQEPKKDDEGREMGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRP0</accession>
    <name>X0CRP0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRP0"/>
    <dbReference type="eggNOG" id="KOG4368">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021915_1_0_1"/>
    <dbReference type="OrthoDB" id="21470at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12323:SF0">
        <property type="entry name" value="CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12323">
        <property type="entry name" value="SR-RELATED CTD ASSOCIATED FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="25"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK96806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="526" mass="58825" checksum="600CBE21AB364B31" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSK4</accession>
    <name>X0CSK4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_02437</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSK4"/>
    <dbReference type="HOGENOM" id="CLU_008279_6_0_1"/>
    <dbReference type="OrthoDB" id="2020758at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02662">
        <property type="entry name" value="Peptidase_C19F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="157"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="547"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="645"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="558"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="645"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK97126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="707" mass="78137" checksum="C8EDF1B2612CFC9D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSM1</accession>
    <name>X0CSM1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_02445</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="5"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSM1"/>
    <dbReference type="eggNOG" id="KOG0786">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="419183at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000006">
        <property type="entry name" value="3-isopropylmalate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004429">
        <property type="entry name" value="Isopropylmalate_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00169">
        <property type="entry name" value="leuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979:SF1">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="15">
        <location>
            <begin position="5"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK97141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="365" mass="38468" checksum="CE24C14F00E9CBF3" modified="2014-05-14" version="1">MAEHNIVVFAGDHCGPEVIAEAIKVIKAVEDISPTAGKFNLEHLLLGGCSIDKTGTPLTDEALAAAKASDAVLLGAIGGPEWGTGAVRPEQGLLKLRSEMCAYGNLRPCFFASDALVETSPLKASVCRGVDMMLVRELTSGLYFGERKEYDGVNAFDTTVYTKPEIERIARLGGYLAKTRGDSRVISLDKANVLATSRLWRSVVDEVYKNEFPDLKVEHQLIDSAAMIMVKNPTQLNGVMIAPNLAGDILSDEASAITGSIGLLPSASLCGVPEVGSKVLSIYEPIHGSAPDISGKGIVNPIGTILSVAMMFRYSLNLAHEAKLVEDAVRAAIDGGLRTKDMGGSTGTAEAGDAIVAELVKALKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTS0</accession>
    <name>X0CTS0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_02723</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTS0"/>
    <dbReference type="eggNOG" id="KOG1061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10254310at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000058">
        <property type="entry name" value="AP complex subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="8">
        <location>
            <begin position="15"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="642"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="707"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="716"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK97566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="745" mass="81611" checksum="1A0E5667EFAF96A6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU18</accession>
    <name>X0CU18_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_04464</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU18"/>
    <dbReference type="SMR" id="X0CU18"/>
    <dbReference type="eggNOG" id="KOG1375">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015718_1_1_1"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097435">
        <property type="term" value="P:supramolecular fiber organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000003">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000009">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="15">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="16">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="429"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK94364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="446" mass="49820" checksum="753554DE6008D7BA" modified="2014-05-14" version="1">MREIVHLQTGQCGNQIGAAFWQTISGEHGLDSNGVYNGTSELQLERMSVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICMRTLKLSNPSYGDLNYLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAHSFRAVSVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGRVAMKEVEDQMRNVQNKNSSYFVEWIPNNIQTALCAIPPRGLTMSSTFIGNSTSIQELFKRVGEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAGIDEEEEEYEEELPEGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWA5</accession>
    <name>X0CWA5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWA5"/>
    <dbReference type="eggNOG" id="ENOG502RMIB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2210152_0_0_1"/>
    <dbReference type="OrthoDB" id="5092844at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="128" mass="14515" checksum="EC4D12B65D0D18E3" modified="2014-05-14" version="1">MNSKHTSGLKRKASDKLETVSMDEFLRRLGPGGRRDWVNKTRGTIDLFEAYESKNPAETTRDNTQLGGNSKAEGTSNTKSSQDMDNIRKIGRLMERVEVLEAENRALKKKNFELEDKQAKVVKLLTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY53</accession>
    <name>X0CY53_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_01979</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY53"/>
    <dbReference type="SMR" id="X0CY53"/>
    <dbReference type="eggNOG" id="ENOG502SJT6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020817_0_1_1"/>
    <dbReference type="OrthoDB" id="412382at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF1">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE CELB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937496" description="Glucanase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK99455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="429" mass="46453" checksum="AAE3B0776EB59C91" modified="2014-05-14" version="1">MKSLSLILSALAVQVAVAQTPDKAKEQHPKLETYRCTKASGCKKQTNYIVADAGIHGIHQKNGAGCGDWGQKPNATACPDEASCAKNCILSGMDSNAYKNAGITTSGNKLRLQQLINNQLVSPRVYLLEENKKKYEMLHLTGTEFSFDVEMEKLPCGMNGALYLSEMPQDGGKSTSRNSKAGAYYGAGYCDAQCYVTPFINGVGNIKGQGVCCNELDIWEANSRATHIAPHPCNKPGLYGCTGDECGSSGICDKAGCGWNHNRINVTDFYGRGKQYKVDSTRKFTVTSQFVANKQGDLIELHRHYIQDNKVIESAVVNISGPPKINFINDKYCAATGANEYMRLGGTKQMGDAMSRGMVLAMSVWWSEGDFMAWLDQGVAGPCDATEGDPKNIVKVQPNPEVTFSNIRIGEIGSTSSVKAPAYPGPHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYU1</accession>
    <name>X0CYU1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYU1"/>
    <dbReference type="eggNOG" id="ENOG502SPQ4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046066_1_3_1"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF13">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="5"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="250" mass="27235" checksum="EFF49489E261DF3E" modified="2014-05-14" version="1">MSPTILAVPGAWHTVESFEPIKKIFTEKGYQFVSQNAPGLHDANATCQDDAESLRTKLLHPLIEDSKDIVVLMHSYGGMYGSQAVRGLSKKEREQAGKKGGVIALIYVSAVTPVEGKTTLDMMGTDAENLPPWVEYNETTGWVKFTGAKETMYHDISDTEAEYYISLLKDQALNSMNTPISYSPLTDENYKGKAGYVICGADRVVPPAGQEMYAAVGGIDRKVTVEKASHAFFATAAEETVDAVLQLVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D078</accession>
    <name>X0D078_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcineurin subunit B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Calcineurin regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Protein phosphatase 2B regulatory subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_00203</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Composed of a catalytic subunit (A) and a regulatory subunit (B).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the calcineurin regulatory subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D078"/>
    <dbReference type="eggNOG" id="KOG0034">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061288_10_1_1"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050801">
        <property type="term" value="P:monoatomic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000047">
        <property type="entry name" value="Calcineurin subunit B type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45942">
        <property type="entry name" value="PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="90"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="131"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK99806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="174" mass="19684" checksum="05BB2F0C5B40E2ED" modified="2014-05-14" version="1">MGNTTSAVLDNLVQGSNFDREEVDRLRKRFMKLDKDNSGTIERDEFLSLPQISSNPLATRMIAIFDEDGGGDVDFQEFVTGLSAFSSKGNKEQKLQFAFKVYDIDRDGYISNGELFIVLKMMVGSNLKDQQLQQIVDKTIMEADLDKDGKISFEEFTKMVESTDISMSMTVDQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0M5</accession>
    <name>X0D0M5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0M5"/>
    <dbReference type="HOGENOM" id="CLU_2740069_0_0_1"/>
    <dbReference type="OrthoDB" id="10476053at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="71" mass="7500" checksum="491C418D70CF5A47" modified="2014-05-14" version="1">MVGGQQERRGAVMVVSCKDRKVGSGLADFGGDSRVKSSINRLRQLENRAMQLTGGGTSADSMEQGSIKCPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1X2</accession>
    <name>X0D1X2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BolA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1X2"/>
    <dbReference type="eggNOG" id="KOG3348">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109462_4_0_1"/>
    <dbReference type="OrthoDB" id="4983at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045115">
        <property type="entry name" value="BOL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735:SF27">
        <property type="entry name" value="BOLA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735">
        <property type="entry name" value="BOLA-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="94" mass="10268" checksum="D0D70D455AF5E062" modified="2014-05-14" version="1">MSQITDESLREAIKQRLEATHVEVTDMSGGCGQAFNSVIVSPQFQGLNSLKRHRLVNAALKDEIAIIHAWTAKCQTPEEYAKTSAANDTAQAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2T3</accession>
    <name>X0D2T3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable enoyl-CoA hydratase, mitochondrial</fullName>
            <ecNumber evidence="2">4.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00944</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="2"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2T3"/>
    <dbReference type="eggNOG" id="KOG1680">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="OrthoDB" id="2018133at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000019">
        <property type="entry name" value="Enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL01081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="290" mass="31481" checksum="86815A5A5C19A6C6" modified="2014-05-14" version="1">MNTFRCMRPVAARVAFQRSTLPRVARAYSSTTYEYIQVSQPKPGVGQVTLNRPKALNALCTPLIKELNQALLEFNVADDTSVIILTGSQKAFAAGADIKEMAPLTFAEAYTKSFIESWSDLTTQVKKPIIAAVSGHALGGGCELAMMCDLIYCTENANFGQPEIKLGTVPGAGGSQRLTRAIGKSKAMELILTGKSLSGVDAEKWGLAARVFPTYEALMEETLKTAETIAGYSKVAVQAAKEVVNKSQDLALRDGVEYERRVFHSLFGSQDQKIGMKAFAEKKKAEWSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3F3</accession>
    <name>X0D3F3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_00878</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3F3"/>
    <dbReference type="OrthoDB" id="10070927at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056513">
        <property type="entry name" value="INO80F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24245">
        <property type="entry name" value="INO80F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="177"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="177"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="82"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="234"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="44"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXL00952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="285" mass="31710" checksum="63D285DB6DED128C" modified="2014-05-14" version="1">MPITLKRKASEADLPPRTPAIPSTLPPSVEEAYRRKCVQLKNRTNEVEDANDAARLRLARIKRQVEKLRIERAFLLEQLAKRTSANVEDSDGSPSPPPTDYQFTIPSELANHQKPKDKPLRTKRGHRKSMMPDSDSKAPVAASFTNTAGSPTSETFSHPPESQPKPAHANGISASDSKKPTSAFELFCLETRPGLESKEKDNEIPVNIEDELTRIWKGLSDGEKDEYEAKFELAMAKSDESKKSPASDKKDDKPAESKQLVQDEDIEMGDDTEDQDTQAGEKVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0D471</accession>
    <name>X0D471_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_07556</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D471"/>
    <dbReference type="eggNOG" id="ENOG502SJKZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010813_2_1_1"/>
    <dbReference type="OrthoDB" id="4116913at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="197"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK89457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="507" mass="57996" checksum="A73619A9B9717494" modified="2014-05-14" version="1">MFFIASDAHDRDPTYLEGLRLLNGNSLFSPQGQQWIKSRTGSTISSNIVDKYRLPYLCSTRLPLANDNHKILQLPDSQIVEELAVRFCSSAQSLVFPLLSLHRFKTRTLPLAYTDGTGSKRYEISAKSCVYGVLIMSDIFGLDSGDDMADTSCWCQRYALEIEGSIPLILREMKINGLESLMMLVIFKYFMGDLESASFLVSVTSCFLFQLGAHIFPSPPDHYDKRNEAHHLRDLFWVCYCIDKDLSHRTGQPPTINDDHCDLTLPPNYVQMQSSNILSSNPCSSRNSSIVPLYPWDIRLSVMKSKIYNDLHSISASRLSETEILRKIRHLDEELEAWRVTLPSDHRPTLSFLEQTPVDAHTNTQAIMLRLSYHHCVILIHQARCRDFQADPSSMNLIDDGHRINFQILVDASRSILIYLEKALPVLAHECFWVIIFYPMTAITTIFSVALLDNRSDPENERLKLLQGFTRLIRQIPIKRLTVAEISHLEFIEELVEEMTRLVSIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4H4</accession>
    <name>X0D4H4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_07651</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4H4"/>
    <dbReference type="eggNOG" id="ENOG502SHWY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002341_6_1_1"/>
    <dbReference type="OrthoDB" id="443402at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056693">
        <property type="entry name" value="DUF7791"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25053">
        <property type="entry name" value="DUF7791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="261"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7791" evidence="4">
        <location>
            <begin position="558"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="76"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK89562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="976" mass="110810" checksum="BE14639B8830C170" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5T6</accession>
    <name>X0D5T6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_07445</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5T6"/>
    <dbReference type="eggNOG" id="KOG0710">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046737_1_1_1"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="41"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="119"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK90007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="214" mass="24238" checksum="EE9A1B18D96A202A" modified="2014-05-14" version="1">MAFFPRNFYNSDASFTPLFRLLDDFDSYSRQGQQNGGTRRSGLTHWQPKFDVRETGEAYELHGELPGMTKDNVHIEFTEPQTMTIRGKTERTYTAGTPPAGLVEGSQSQGAIAEGEGNDENKNSHHAKVEDEAEAKAHESTEVTHHQQSKEVEKKPGDQSKYWLTERTFGEFSRSFNFPTRVDQDNVSAKFKDGILSIVVPKAKKHESRRINVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0D703</accession>
    <name>X0D703_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D703"/>
    <dbReference type="HOGENOM" id="CLU_1503487_0_0_1"/>
    <dbReference type="OrthoDB" id="4430588at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="42"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="181" mass="20867" checksum="EC2654F0497306A1" modified="2014-05-14" version="1">MAFTIYYKHGQMRARLCPTAPFVVPQQLSQVKRDQSALFKTLPNEILLEITSYIEVEDRLCLGLTCKSLFYRLCQSTDFHIISASGHAYSDIPYCSHIKDLLKRMRPLTPKGQPKRTMALCCDCLRYRPKRVTYWKEMISKKDLRSLDLCAANDAAESWCTGESIQCPGCWFKGESDYIMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0DA18</accession>
    <name>X0DA18_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C-8 sterol isomerase</fullName>
            <ecNumber evidence="8">5.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Delta-8--delta-7 sterol isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_00333</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Steroid metabolism; ergosterol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ERG2 family.</text>
    </comment>
    <dbReference type="EC" id="5.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DA18"/>
    <dbReference type="eggNOG" id="KOG4143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085469_0_0_1"/>
    <dbReference type="OrthoDB" id="347124at2759"/>
    <dbReference type="UniPathway" id="UPA00768"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006716">
        <property type="entry name" value="ERG2_sigma1_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10868">
        <property type="entry name" value="SIGMA 1-TYPE OPIOID RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10868:SF1">
        <property type="entry name" value="SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04622">
        <property type="entry name" value="ERG2_Sigma1R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK99989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="235" mass="26092" checksum="B28D0E91621036BB" modified="2014-05-14" version="1">MAKNKSKSKSSAAAASQGSGLNKLLLVLGLLTALLSSVVYFVEQNLNQFYIFDLDHLDDLSKRAIAKHGEDTRSVVQYIVTELNEKVPEHINLKEEWVFNNAGGAMGAMYIIHASVTEYLIIFGTAIGTEGHTGRHTADDYFHILSGTQLAYVPGEYKAEVYPAGSIHHLRRGDVKQYKMPEGCFALEYARGWIPPMLFFGFADGLSSTLDFPTLWDTTRITGREMINNLIKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0DFN2</accession>
    <name>X0DFN2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hypervirulence associated protein TUDOR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DFN2"/>
    <dbReference type="eggNOG" id="ENOG502S40C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077179_0_0_1"/>
    <dbReference type="OrthoDB" id="2131339at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021487">
        <property type="entry name" value="DUF3140"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021331">
        <property type="entry name" value="Hva1_TUDOR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40630:SF1">
        <property type="entry name" value="DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40630">
        <property type="entry name" value="POSSIBLE DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11338">
        <property type="entry name" value="DUF3140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11160">
        <property type="entry name" value="Hva1_TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hypervirulence associated protein TUDOR" evidence="2">
        <location>
            <begin position="248"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="310" mass="34907" checksum="6585D3AFE6BBD433" modified="2014-05-14" version="1">MKGNDEVIQEFNEVVNMTASELEKWLKSDDSNSAGWPKEDENGETVGHDSGRKIVEILKENPKKEPEKYTDEQVQHMRKVVSYCKRHLAQETKANNDKSPEEVKKTKSYASLKNWGHDFLKAQGKENGSEKKEDREDKEEANDDAEDAEEEGDDDEKQTGEKRRATRSQTGSNKKRETRKGESTKSNDEEEEEEEDDDDEKKQGQKKQSNGQSKKSNGSSKKEEDAEEEQDDDEGGDDSGTKKGPKKGETVSWNWGQGQPKGKVLDVKAEDTTITTKNGNEVSRKGDEEDPAVVLDTGKNKAIKKAHELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0DX56</accession>
    <name>X0DX56_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">General negative regulator of transcription subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_01545</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1831">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000286_3_1_1"/>
    <dbReference type="OrthoDB" id="1933107at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20710">
        <property type="entry name" value="NOT1_connector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000012">
        <property type="entry name" value="Ccr4-Not transcription complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.840:FF:000002">
        <property type="entry name" value="Ccr4-Not transcription complex subunit (NOT1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="13">
        <location>
            <begin position="520"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="12">
        <location>
            <begin position="713"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="11">
        <location>
            <begin position="923"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="10">
        <location>
            <begin position="1204"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="9">
        <location>
            <begin position="1818"/>
            <end position="2185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1443"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00074459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK98747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="2189" mass="245538" checksum="38BAC7460A215A75" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0DZT6</accession>
    <name>X0DZT6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">26S proteasome regulatory subunit RPN2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_00094</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the proteasome subunit S1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DZT6"/>
    <dbReference type="eggNOG" id="KOG2062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002323_0_1_1"/>
    <dbReference type="OrthoDB" id="261572at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000017">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016642">
        <property type="entry name" value="26S_Psome_Rpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048570">
        <property type="entry name" value="PSMD1_RPN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040623">
        <property type="entry name" value="RPN2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18004">
        <property type="entry name" value="RPN2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21505">
        <property type="entry name" value="RPN2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015947">
        <property type="entry name" value="26S_Psome_Rpn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="9">
        <location>
            <begin position="51"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="9">
        <location>
            <begin position="240"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome regulatory subunit RPN2 C-terminal" evidence="8">
        <location>
            <begin position="912"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="405"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="964"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1088"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1138"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="407"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="972"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="991"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1152"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1168"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1190"/>
            <end position="1200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK99632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1200" mass="131217" checksum="CAE29C713CDFD2EC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3J6</accession>
    <name>X0B3J6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Asl1-like glycosyl hydrolase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979540">
        <property type="protein sequence ID" value="EXK76316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3J6"/>
    <dbReference type="HOGENOM" id="CLU_1115801_0_0_1"/>
    <dbReference type="OrthoDB" id="43654at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="1">
        <location>
            <begin position="56"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="249" mass="28366" checksum="D594539721D5D659" modified="2014-05-14" version="1">MSPAQATVLGTDDYKADLITDAELVTKPKRGTAFDHFSRCYQARNWVSGIEDRSADLRFFTLSWEAEGDSTTNLSLCMLKVLPGGFKEMVSLNKPDKPDQANMTPEDAVLDHIQYLNAYSVEISIGATSVSNIIQESESIWWLSDLFEVSSRLKPFYKVNFCPDHWSSSDIQFRDQWLPDQLNCEACDGSAMWLLELAVLGNDEIIQLFPGKRNPKEEKLEYTGIFFHFYIKTRYLMLSDACLSPTRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3V7</accession>
    <name>X0B3V7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_18819</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658719">
        <property type="protein sequence ID" value="EXK76441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3V7"/>
    <dbReference type="HOGENOM" id="CLU_000288_182_0_1"/>
    <dbReference type="OrthoDB" id="427518at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="7">
        <location>
            <begin position="20"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK76441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="307" mass="34001" checksum="C16F68CAFA25CCC4" modified="2014-05-14" version="1">MSQYGLTKWHDAEDKAVVDIVFVHGLRGGRESTWTKDGVIWPKELLAKDMPKSRILSFGYDASIVHSDTADVTQGSLVYDARELCSLLDAERKRTNTANRPIVVVGHSLGGLVLAQVVYGGNAAAEGDSINSIAQKVTGMIFLGTPFYGSKIAGWGDAVRRIYDLIRKTDKNTLKNLNLDSARLKGLREGFPEVIRKRNQTSTKIAVVFFFERKTTYGVWIVKEENAAYPGVGEILPMQANHIDICKFDDVEDDGYKKVKAKIKEALQAAEITGDEGSNTYIINNDGKIVNLAQRDIQIDTQTINFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5H3</accession>
    <name>X0B5H3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658653">
        <property type="protein sequence ID" value="EXK77011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5H3"/>
    <dbReference type="HOGENOM" id="CLU_2922736_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="61" mass="6993" checksum="8EBE152DE401CA65" modified="2014-05-14" version="1">MAPPSVPTEVKKQRERERGRKRRQQSRCQGQAERLREADSHESVRLVSQVHHTAAGATDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5N9</accession>
    <name>X0B5N9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979419">
        <property type="protein sequence ID" value="EXK77076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5N9"/>
    <dbReference type="HOGENOM" id="CLU_2263924_0_0_1"/>
    <dbReference type="OrthoDB" id="10268516at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="103" mass="11853" checksum="E340EFA63696D9C4" modified="2014-05-14" version="1">MPVPPSRYESTDLVIFNPEDERNCGMPEAVREYFNSKVVPDCTEPTQEQWKRFTMNKGSGYERTEFLVRQVPFYRYRPNDGAAVICGLSIAVLSSLGWKWIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0B715</accession>
    <name>X0B715_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_17733</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979383">
        <property type="protein sequence ID" value="EXK77566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_6_16_1"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050349">
        <property type="entry name" value="WD_LIS1/nudF_dynein_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44129">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="5">
        <location>
            <begin position="382"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="943"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="985"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1066"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1108"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1150"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1192"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1233"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1298"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK77566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1440" mass="159705" checksum="562FCEE5A6C9F4AD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8E1</accession>
    <name>X0B8E1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dynamin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658522">
        <property type="protein sequence ID" value="EXK78410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658522">
        <property type="protein sequence ID" value="EXK78411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658522">
        <property type="protein sequence ID" value="EXK78412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658522">
        <property type="protein sequence ID" value="EXK78413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8E1"/>
    <dbReference type="HOGENOM" id="CLU_010389_2_0_1"/>
    <dbReference type="OrthoDB" id="3598281at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681:SF3">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin N-terminal" evidence="2">
        <location>
            <begin position="279"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="780" mass="86675" checksum="AB660C63CF1189B4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8N3</accession>
    <name>X0B8N3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979358">
        <property type="protein sequence ID" value="EXK78510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8N3"/>
    <dbReference type="HOGENOM" id="CLU_2638164_0_0_1"/>
    <dbReference type="OrthoDB" id="5003250at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="76" mass="8079" checksum="754B9DFD04298F77" modified="2014-05-14" version="1">MAKVVLPTMSSNEEGGNSPTHSSGSRQSDSTPRNDQPAPADPVNGDDTSSTENSDGNFNTKDFAPIDVTHNHKEDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BA04</accession>
    <name>X0BA04_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658489">
        <property type="protein sequence ID" value="EXK78985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BA04"/>
    <dbReference type="HOGENOM" id="CLU_067863_1_0_1"/>
    <dbReference type="OrthoDB" id="5019664at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF3">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="219" mass="23020" checksum="36633554E572D9F3" modified="2014-05-14" version="1">MPAKPNPTLPSNGGASELPEPSQGAALKHIALGFGIQNYTCADTDTTPTSVGALAVLYDVTHLYPGQSHSSLTQAEWASLPGEVLNTLKVPLNLNENGIGASPIKPFPKKQDLKVRSLSKKISYLGHHYFNSVGVPTFDLDKACQLLIAKKIDGIKAPGSSPSGPDGTGAVDWLFLGDAGGSHGISFVYRVLTASGASHGCKTKGVDSTSYAAMYWFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAY9</accession>
    <name>X0BAY9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979666">
        <property type="protein sequence ID" value="EXK75988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAY9"/>
    <dbReference type="HOGENOM" id="CLU_1610835_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="165" mass="18325" checksum="60145923694BB648" modified="2014-05-14" version="1">MKFGHCGEIATEDKPHAEPCNKPAKCANCYGPAPADHESCPAKPIRKNGKLQRPTKKELSAIRRLGRKQYQAKNLNRTTESGENTNNVIINDEDAHSDHSDTTIPDLPAEKTGEAEDATDRDMDTGPSEVEPLAQETRHRWASRARKPITYTNDPYAFLGNDEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAZ6</accession>
    <name>X0BAZ6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658490">
        <property type="protein sequence ID" value="EXK78946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAZ6"/>
    <dbReference type="HOGENOM" id="CLU_065610_0_0_1"/>
    <dbReference type="OrthoDB" id="5087721at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853:SF1">
        <property type="entry name" value="LIPASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="226" mass="24867" checksum="A3A466388E214384" modified="2014-05-14" version="1">MRHCQQVLAIANAADFETLGTAFDFDFYATADNFSTSKPGDLLKLAAIDSSHLDVPAGMTSFRFQYTSRDLDESPVPSTGFIAFPFAKLTQGRKFSLVAYAHGTIGVFRGKGADGAAYNVQNIFNVLTGQGQAASGQSGATPLVQIWHDQSYDKMYSQDAFILKEYLDDFDKALWWAFGMAGFALACQIIALQDKSTTHEEIQDEVEQLTSQFTANVNEVFETAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBP9</accession>
    <name>X0BBP9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979697">
        <property type="protein sequence ID" value="EXK75939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBP9"/>
    <dbReference type="HOGENOM" id="CLU_528966_0_0_1"/>
    <dbReference type="OrthoDB" id="5369347at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="515" mass="59450" checksum="6D26361AEF21AFC6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCL5</accession>
    <name>X0BCL5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658704">
        <property type="protein sequence ID" value="EXK76568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCL5"/>
    <dbReference type="HOGENOM" id="CLU_028281_0_0_1"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF4">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="152"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="467" mass="52755" checksum="29547D45FCF11BC1" modified="2014-05-14" version="1">MGIDAGFDMVPQLSRTEADHEAWDLLINMVKERYKADERMEINSNYISFNAGEGPILPFEGFKFLRFSSKVSGSTATTTGVWDIIKAVTRIAKSIFGSRVRYWSEAADDYGYYKWDEVHASIESYDKVDGWAVPETTASPSADLTSSEDISSYLCEVQSIPGRGKGLIALRKITMGMRVLIEKPILQTRNAPSALLEPTIARDLKSLTKEKQRQFLSLHNNFPGKYPFSGIMRTNALPCGSGATVGAVYPTICFINHSCRANAHNSWNGNLEQETIHAIRDIEPGEEITISYDHGGPSISRKPWLKEKFGFDCDCPVCRLPLVELEKSDKRRKQIQQLDQDIGDPVRMISRPSASLLNCRSLLQVLKEEFEEDTSILVARANYDAFQIAIVHGDLARGAVFADRAYQVRLICEGEDSSDTERMQRLAEDPMIHPSFGAYSMRWKTKKGQVPRELMGDEFENWLWRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCV3</accession>
    <name>X0BCV3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_18617</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979467">
        <property type="protein sequence ID" value="EXK76648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCV3"/>
    <dbReference type="eggNOG" id="KOG1802">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011668_0_0_1"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="6">
        <location>
            <begin position="198"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="7">
        <location>
            <begin position="502"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK76648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="775" mass="87972" checksum="FE261BDCF63CE5D3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDV5</accession>
    <name>X0BDV5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucan endo-1,3-alpha-glucosidase agn1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979342">
        <property type="protein sequence ID" value="EXK80001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDV5"/>
    <dbReference type="HOGENOM" id="CLU_019141_3_0_1"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051118">
        <property type="term" value="F:glucan endo-1,3-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005197">
        <property type="entry name" value="Glyco_hydro_71"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03659">
        <property type="entry name" value="Glyco_hydro_71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="44471" checksum="3F371B464513C8AC" modified="2014-05-14" version="1">MLGDITEEHAPKDIADTIAMGRDGFFLNVGYPKLDSVPQTLRHLYSYADDLVSKGGKFKLALSLDLYATGTWCYDKKLGNDCGGPKEYETSLKSFLGRDSYLRYGPDNFPFITNFSTGRQTDKDFTAWKKSFANEMYFVPGIDDTPGFWESYPAWWDYWGDLIDGASVWESAWPEAHGTNEGDLSRDIKAMGSSEEEQELMMPSSHQYTSVQERDKLSLNYGANLYRRGEMKVVKRMENILSMDPQLHIIQLLTWNDGPESHHFGNLWPEQNADAQPSQYASPDGSDHTALQPLYSAFIHAWKNGGFMVPAFSKRDEAIPEGALWHKSIFRSTTCPGGESSVKYFQAPNGTDAGQDALHWALVVPANAAGFIVNVISNGERISSKSLQTGLISKRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFT6</accession>
    <name>X0BFT6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_14862</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658439">
        <property type="protein sequence ID" value="EXK80656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFT6"/>
    <dbReference type="HOGENOM" id="CLU_027816_3_1_1"/>
    <dbReference type="OrthoDB" id="655540at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF683">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="49"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK80656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="469" mass="50554" checksum="E3FCAB3DE3A2E3EF" modified="2014-05-14" version="1">MSALNERKIDPEGLSTMPSQGGDVHDSNEIVHDAVFGEISEDGPDYRNVGWIGSSVLMMKIQIGLGVLALPAAFNDVGLIPGVILLSFVGGIVTWTAWVVGGFKLRHREVYGIDEAVQFMFGRVAREAFGFIFCLFWVFAAGSGMLGISIGLNAITSHGACTAAFVGVAAFLGFSIASIRTLGRLAWFAWFGLVCLLAAIFTVSISVSVQDRPDAAPQDGDWVSDYKLVNRPTFTGAMNAISTFLMAYSAIPGFFPIAAEMRNPRLYTRSLILCHTVVSIVYIVIGCIVYYYCGSYVSSPALGSAGKLMKKICYGLSLPGLIVTTVLTIHFASKYIFLRILKGTEHLNKGTLRHWATWFSCTFGCATVSYIIASAVPSFGSLASLIGAFFGTLLCIQPMGCMWLYDNWSAGKQDRSRWWMLQVCWSGFVIVVGTIILVGGTYGSVLSIKEVYGASGGHGAFSCADNSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGH4</accession>
    <name>X0BGH4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658591">
        <property type="protein sequence ID" value="EXK77584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGH4"/>
    <dbReference type="HOGENOM" id="CLU_3068759_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="53" mass="5893" checksum="ACA2AF2587014E9A" modified="2014-05-14" version="1">MQLRHANSEIPPFAFDRDKATRAQADAIATGLPPIDWVKAVTKRAAECDVNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH19</accession>
    <name>X0BH19_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Omega-6 fatty acid desaturase (Delta-12 desaturase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14448</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658430">
        <property type="protein sequence ID" value="EXK81116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH19"/>
    <dbReference type="eggNOG" id="ENOG502QQNB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033094_0_0_1"/>
    <dbReference type="OrthoDB" id="1461976at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="325"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="3">
        <location>
            <begin position="137"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="479" mass="53760" checksum="5436913629C5C4C7" modified="2014-05-14" version="1">MASVSTSALPKQNPALRRTVTSTTVTDSESAAVSPSDSPRHSASSTSLSSMSEVDIAKPKSEYGVMLDTYGNQFEVPDFTIKDIYNAIPKHCFKRSALKGYAYILRDIVLLTTTFSIWYNFVTPEYIPSTPARAGLWAVYTVLQGLFGTGLWVIAHECGHGAFSDSRLVNDITGWVLHSSLLVPYFSWQISHRKHHKATGNMERDMVFVPRTREQQATRLGKMAHELAHLTEETPAFTLLMLVLQQLVGWPNYLLTNVTGHNYHERQREGRGKGKKNGLGGGVNHFDPRSPLYENKDAKLIVLSDIGIGLMATALYFLVQKFGFYNMAIWYFVPYLWVNHWLVAITFLQHTDPTLPHYTNDEWDFVRGAAATIDREMGFIGRHLLHGIIETHVLHHYVSNIPFYNADEATEAIKPVMGKHYRADVQDGPRGFIRAMYRSARMCQWVEPSAGAEGAGKGVLFFRNRNNVGTPPAVIKPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH66</accession>
    <name>X0BH66_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658541">
        <property type="protein sequence ID" value="EXK78163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH66"/>
    <dbReference type="HOGENOM" id="CLU_087345_0_0_1"/>
    <dbReference type="OrthoDB" id="5091810at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="213" mass="23743" checksum="892F314E04E1F7ED" modified="2014-05-14" version="1">MDSPHNPSDRCEATVEVRALESQQKDDMPQMKIIPCLEESEEDRLKCDQSSISPTYHNEHTPKAANTNTGNIPAQSHDRLDTTPESNKTVANLDDISEHKLPNASLSVREKSPKASKSKNEITKKDAISSPTTSKATSLPGIKSFQPDVFMGQKRSHDIQGRPSGIGLRELHERSLQPRFTCGTARWKEMGAQLLPITKDVTQLNAKAEYYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHF6</accession>
    <name>X0BHF6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF2961 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979335">
        <property type="protein sequence ID" value="EXK81241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHF6"/>
    <dbReference type="eggNOG" id="ENOG502SKR2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039495_0_0_1"/>
    <dbReference type="OrthoDB" id="3426554at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021345">
        <property type="entry name" value="DUF2961"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11175">
        <property type="entry name" value="DUF2961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="462" mass="52916" checksum="DBF9A763829329A4" modified="2014-05-14" version="1">MSNPISSLQGGILNNVAKLKTARTARVSSWDHSGLNEDAWVIQPGETAVLADLEGPGTITHLWFVQTCRRIVGPGLIPYSKSGVAMMEVHNALGLNYEVSDPDYYRKVIIKMYWDDSETPNVLAPIGDFFCLGHSMAANFQSLPFTVSVKPSEEKKFGGAAAFNCYLPMPFNKRARIEIENQNDEAYFQYFYIDYELFPEPLSKDTLYFHSHWRRENPTNGWAPENIQTNSLETQVPNLDGKGNYVILETEGAGQYIGCNHSVAHFQGTWWGEGDDMIFIDDDTWPPSMHGTGGEDYFTQGWGMQKNAYPFCGTIIHEEDVPNHQVSYRWHLADPVRFSKKIRVTMESGHANHLRDDWSTTAYWYQTLPGPKLSIQPVEERIPRKPDFPAGKRPEPPNTESLDPKRKAMIQQHQDRMEAFVQDRNQWLERRAKATQERSKKNIEHAKDIRTRFYESLKGDNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIS1</accession>
    <name>X0BIS1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIS1"/>
    <dbReference type="eggNOG" id="ENOG502SQFY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033726_4_1_1"/>
    <dbReference type="OrthoDB" id="5973539at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF8">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="335" mass="38463" checksum="3CE9E43AA5AE1291" modified="2014-05-14" version="1">MRDTVKDGSANRDDAVSRKRTSSKDDDAPPAKRRVLTTARREQNRQAQKAYRERQKQERIRLKQEKAQAQASCGQRLRPLLKREELPSRDSSGKQRSMREINLCDEGFLETVDTSVSTPSSQNNSVKKLEPNFPDLYMNMLQFSPAAIFTSCLTNAVSLGLDPSVIANCGVEHISPFYQPNLSITLDHATLIQAGSNILSRFNNTSIPVHLRPTMAQILIPHHTSLDLIPLPFLRERAIMLSAAMPHVFNNWELKLDIYERGGLTIWRLKHEKGESVRDTYPPWDMKSWEASPWFLKKWCMLMGREYDKMHNQSIGWQVVRDMISSRDIQRLTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK12</accession>
    <name>X0BK12_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_16556</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658502">
        <property type="protein sequence ID" value="EXK78794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK12"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_3_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF123">
        <property type="entry name" value="GMC OXIDOREDUCTASE (AFU_ORTHOLOGUE AFUA_2G01770)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="256"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="491"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="529"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="490"/>
            <end position="491"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK78794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="549" mass="59850" checksum="2659BC7BD9743A47" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK82</accession>
    <name>X0BK82_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_16079</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979349">
        <property type="protein sequence ID" value="EXK79283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK82"/>
    <dbReference type="HOGENOM" id="CLU_024655_0_0_1"/>
    <dbReference type="OrthoDB" id="9930022at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK79283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="410" mass="46937" checksum="2C366458864B4342" modified="2014-05-14" version="1">MSRLGLTRYEVKACKACQSSKRKCTKQQPKCRRCDLRGLDCLYEPLPNTFVYQATQNCGGQASPLAAFPEARLLHSGQDDSWFELVDIEVESHQSTPGTISLEDLKVAWFLDPDSWRTVPIQESNRAHLTTDMIRGLLYQTRDWLSDWTRSGSNVFVHHELYRNSLPDCISDAFTTLSSYLSRTPETNEMVLRIAEQNAERLLVSEDGRRTSGDTLSSLSRVQALLVYCTIRLLDGDLRQRHKAEQHLQTLQDWTKEMMNDALKATNNGDMIMKNHLANVSPQYFTLPLLLGQLSPEQLLWHSWVLSESIRRTWCVSMGLQSGYELLKTESGPCYGTLPITTRKGLWEARSAFTWTKMCAESNIGFMCRNDHEKVMMDMEPGDIDDFALCMMELDIGPDRMARWRSERAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKC3</accession>
    <name>X0BKC3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-arginine deiminase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658493">
        <property type="protein sequence ID" value="EXK78914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKC3"/>
    <dbReference type="eggNOG" id="ENOG502QVJA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015851_0_0_1"/>
    <dbReference type="OrthoDB" id="5102063at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004668">
        <property type="term" value="F:protein-arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004303">
        <property type="entry name" value="PAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013530">
        <property type="entry name" value="PAD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036556">
        <property type="entry name" value="PAD_central_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10837">
        <property type="entry name" value="PEPTIDYLARGININE DEIMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10837:SF8">
        <property type="entry name" value="PROTEIN-ARGININE DEIMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03068">
        <property type="entry name" value="PAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110083">
        <property type="entry name" value="Peptidylarginine deiminase Pad4, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936510" description="Protein-arginine deiminase C-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Protein-arginine deiminase C-terminal" evidence="3">
        <location>
            <begin position="191"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="637" mass="70459" checksum="15C82FBAEB49A4A9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLW0</accession>
    <name>X0BLW0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658455">
        <property type="protein sequence ID" value="EXK79883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLW0"/>
    <dbReference type="HOGENOM" id="CLU_013484_0_0_1"/>
    <dbReference type="OrthoDB" id="5079701at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="585" mass="65228" checksum="804B5931087435D0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLX5</accession>
    <name>X0BLX5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HpcH/HpaI aldolase/citrate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_12809</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLX5"/>
    <dbReference type="eggNOG" id="ENOG502SJZ2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059964_4_0_1"/>
    <dbReference type="OrthoDB" id="2326446at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="27"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK82841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="276" mass="29306" checksum="781D099F211C5E13" modified="2014-05-14" version="1">MLACQNSLKTRVANGQLCKALGVRLITNPQVVQLAKNANFDSLFIDLEHSTLSLDDAGKLCGAGLALGITPFVRVPHQCGNGFIQKVLDAGAMGIIFPHVQNSDEAKAAVAISKYPPQGCRSITGQLPALSLKSYPQADVIRETNEHASTVFVMIENEGAVQRVEEIAAVEGVDVLLIGSNDLAIELGAPADFRSDRFRQALMRVSKACRKYGKVMGLAGIYGTPDIHDWAIHTLGVRFMLCQQDSGLIAGAAAKCLAAVEMVENAPSSKSTNGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMG5</accession>
    <name>X0BMG5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_15368</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="KI979340">
        <property type="protein sequence ID" value="EXK80088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMG5"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000003">
        <property type="entry name" value="Peroxiredoxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF128">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="12">
        <location>
            <begin position="4"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="179"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="10">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK80088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="213" mass="23912" checksum="B335BCDE9BCB7FAF" modified="2014-05-14" version="1">MSSAFVQRPAPDFSATTLFPGGEFRDIKLSDFKGQWVVLLFYPMDFTFVCPTEIIQYNNALDRFREINTTVLGVSTDSHFTHLAWVEKPRKQGGLGPDLELPLVADKSTKISRSYGVLIEDEGIALRGLFIIDPKGVLRQITVNDLPVGRDVEETIRLVKAFQFTDEYGEVCPAGWQEGGKTMKADPKGSLEYFSEQGENDSNETRIPINTRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMZ5</accession>
    <name>X0BMZ5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucose-repressible alcohol dehydrogenase transcriptional effector</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_15206</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979338">
        <property type="protein sequence ID" value="EXK80263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMZ5"/>
    <dbReference type="eggNOG" id="ENOG502SAJ4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027499_1_0_1"/>
    <dbReference type="OrthoDB" id="1517790at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="17"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK80263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="57907" checksum="A4079F06848B00FF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPP8</accession>
    <name>X0BPP8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658434">
        <property type="protein sequence ID" value="EXK80873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPP8"/>
    <dbReference type="HOGENOM" id="CLU_021768_10_2_1"/>
    <dbReference type="OrthoDB" id="5404599at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF58">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="147"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="377" mass="42380" checksum="C3B32A7F53D0F9F7" modified="2014-05-14" version="1">MSGENYSESLRSTLKSRVSKAQSQSTAAQWNMAQYHKLGIALKKDPEASIVDLLSRSYPKQLKSLKDSSSSRCTQNAHLPTGDARSRLVATEPCTILRNLSTEVQELLNSGSLSEALLEVLNQGDILFQTACVMVLKIGESIVVKMTQADTLTEYHSLCYLQQHLPTFPAPRPHGLLQFNGYNFLFMAFIPGIDLEKAWPQLGDDEKQAVSGDLDELFSLLRSIPFSNGTPFGGVSGEGCKDIRRHLRMSPESIYDEEAFQDFVVSGTRSASPLYTNLLRSLMPPTSAKCVFTHGDIRPANIMVKKDLEGKWKVTAIIDWEASGFYPEYWESFKMTNNLTPRDESDWYMYLPAGLSLRQYPVQWLVDRVWDPLMINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQZ7</accession>
    <name>X0BQZ7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQZ7"/>
    <dbReference type="HOGENOM" id="CLU_1230003_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="225" mass="25339" checksum="45192A39CFF8B128" modified="2014-05-14" version="1">MAFTGIGLDDLDKWSRAGCSLGKYLFAQFSKGPSIHLTPELKIYVRAKTFYGLIPLKHMVSKTEVLEFEIWSPEDTDEGSAISSDPRFDNCYVFSPAHKPHGLFDGGIEFRLTTEKGKSTLDLQSRTLFTLDIEELSEKDKRVDYSKPMLADPLAQGTITSIKHWISECDREQAQTHAICSVSEPHFLPSRLIRVRPRGSKCELKLLSGKMLKEEGGRYAALSYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTA8</accession>
    <name>X0BTA8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LITAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTA8"/>
    <dbReference type="eggNOG" id="ENOG502TAYE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1015783_0_0_1"/>
    <dbReference type="OrthoDB" id="5599753at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006629">
        <property type="entry name" value="LITAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10601">
        <property type="entry name" value="zf-LITAF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00714">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51837">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935981" description="LITAF domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="LITAF" evidence="2">
        <location>
            <begin position="161"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="274" mass="29878" checksum="902671AF4F5814C0" modified="2014-05-14" version="1">MLPGFVTCLIFLSLIMDSKDRQLYHVPAGPLPPPSYSEATTTDPLTTDGFVSPMTTTSSPVAFNAAVSPMAMTPITSRSTESFTLPPLTETDLDSRNHSTLEVAHSPRADSDCLPQAVIHDAPELALVEYAPNRDNLPMISTTSQTNIEYASGLEVIPAPPGSNTVTPLHLLGDQPEAIDCPFCLRRSETRVKKKPSSTTHLQAVALLMTTVCGAVAPYMAKWSFDIEHICDNCQNRVMYRARGKDIRICKAPAAWKEESKYPDVKNSMSPVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTD4</accession>
    <name>X0BTD4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658423">
        <property type="protein sequence ID" value="EXK81739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTD4"/>
    <dbReference type="eggNOG" id="KOG0987">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164176_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="88" mass="9786" checksum="98DB1BAC50B1B021" modified="2014-05-14" version="1">MPRMRGPTPPTYPPTPPPLQRKRKASDAVPKSENDHQSQTLPPSPKRTQRELSFISISSGGHEDAQHDQLAPPDDRPVINTEPELSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUP4</accession>
    <name>X0BUP4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_13441</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUP4"/>
    <dbReference type="HOGENOM" id="CLU_567459_0_0_1"/>
    <dbReference type="OrthoDB" id="5086878at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF99">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="126"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="50907" checksum="296239C4C45BBDD2" modified="2014-05-14" version="1">MYLELDKGLQVACTQPRRVAARRVAERVAAEMDVRLGEQVGVHHRDHNNTNEKTRLKFVTEGILLRQYQEDPTLSRYSCVIVDECHERTADADILLALLKKTLVNRPELKNWFPSRDSASSNADSGLRPTRFECREAYPREKSPREHTRLSVQQIQVAVSKLRKGIKDLDVVPLYSSLPQDEQVKAFHSGDKRMYIVATNIAETSLTIEGVAHVVGMATLLPAPISQASAEQRAGRANRTRAHPPGIHKADIKKYILILKSVGYIAVGTFDFLEPHHPEVYVRGLQDLKAMNMIHNNGNITPPGNGSLELPIEQAWYNAFVRGLKLGCLDEIISIAAFSSTRHSIFANPYPQRYAAATEHAQFTNPVSDHMTELNAFYKWRHQCKLGAKEAAVWCHETLLNVEALNEAFKLRKEMLDECGVLLGIESVPALTFDDEEYDIKIRKAIARQTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW09</accession>
    <name>X0BW09_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW09"/>
    <dbReference type="HOGENOM" id="CLU_034311_3_0_1"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF11">
        <property type="entry name" value="D-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="3"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="337" mass="37862" checksum="9C937F387BD7D566" modified="2014-05-14" version="1">MARITIVGAGIVGLAIAAQLSRIHDITVIAKNLPGDDPTLEWASPWAGANFVAGYCSSPRDRKMQRDTFIELWRLANRFPESSVKRIPMEEFFDEERTEDDLWFKDFVPDFRLLEKEELPEGAKGGITYTTIVLNPNIFLPWMRSTLERSGVRFMRLDLHALSDARHLGHDVLINAAGLGPRHLVDVKDPDMLFLKGQIILVKSDYKKCLMRDDGKDYTYVIPRLDGTVIMGGIRDPDISNTEVDLDIDKDITRRVNKSLPAHFSADPADHDIVGHNVGIRPYRSTGMRIEKQIKDGQNIVHAYGITGGGYIFGFGVAREVVKLVNELLYPAGKAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXG0</accession>
    <name>X0BXG0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXG0"/>
    <dbReference type="HOGENOM" id="CLU_010595_7_1_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF31">
        <property type="entry name" value="LAEA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="38062" checksum="2C7D4A3630F0FF4A" modified="2014-05-14" version="1">MSSPRAPEEEVIQPDTGLQSVTDDEAYDNESERSSLTSLTSSILHGKVEGGRTYAVYGKEEYGLPMDEAELDRIDMCHAKYCALIGKNRYLAPLEKPQRILDLGCGTGIWSIEMAEEFPSAEVIGTDVAPTQPDWVPPNCHFEVDDIEREWTWKKDSFDFVFARDLLLAIRDWPALIDQTYTHLRGGGWVEFQAIVGVLGCDDDSIPEDSYLRKFSTMMEQGSAKFGASLTDPMRWKGWLEERGYQNVTERVFKLPFNPWPKDPRMKLLGAWEMENLLSGLEAMVTRMFQKGLGWTDAEVTVFLAFLRKEIKNPRMHGYWPYYVVYAQKPQGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXM3</accession>
    <name>X0BXM3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXM3"/>
    <dbReference type="eggNOG" id="ENOG502SQF6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_399574_0_0_1"/>
    <dbReference type="OrthoDB" id="5362630at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF2">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="187"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="522"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK86945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="689" mass="76916" checksum="AB8F74049CD3A3AC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYK6</accession>
    <name>X0BYK6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="3">FBP aldolase</shortName>
            <ecNumber evidence="3">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2 3">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="3"/>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYK6"/>
    <dbReference type="eggNOG" id="KOG4153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040088_4_0_1"/>
    <dbReference type="OrthoDB" id="2558351at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050246">
        <property type="entry name" value="Class_II_FBP_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304:SF0">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="289" mass="31614" checksum="0A3F3B8EADA108A4" modified="2014-05-14" version="1">MTFTWEPQNNKTCQILKAAEDGGYGVVAPIAYNIEHILAFVRAAEAKRSPLIIQVFPWAITFSSGLLIHAAAHAARNASVPIAIHLDHAQDEAIIRHAADSLPFDSIMVDMSHYEMEENLSKTKELVSYCHARGIATEAEPGRIEGGEDGIADTADLEGALTTAEQVEDFIATGIDFLAPAFGNVHGEYGKRGPVLEFDRLEMIRSRVNGRVRVVLHGTNDFPEDTMKACIKGGVSKVNVNKLVLDDYLIHIKEQASKLNLTTLMEEGVEKAQKLTEWQMDVCGSTGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYQ5</accession>
    <name>X0BYQ5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYQ5"/>
    <dbReference type="eggNOG" id="ENOG502SD7M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099924_0_0_1"/>
    <dbReference type="OrthoDB" id="1193027at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="19224" checksum="2B72C95264705848" modified="2014-05-14" version="1">MPTLQDNFVQCADKTCADGKDGAMAWANEICGKLGKPIDLGGSGGSPKTDETTVVNVPTTSAGGEVKPTTEAEKTTDEVPTTTTEAKTESKVEETSSDKTSEVTSESSAGETTASSVKTTVSKPKETNDASGSAAEATADQTSDDSVVTITGTADTATATPSPTDGSNVANSAGPNFYAAVGVAAAFWQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZU4</accession>
    <name>X0BZU4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">pectin lyase</fullName>
            <ecNumber evidence="8">4.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_11773</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.10" evidence="8"/>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZU4"/>
    <dbReference type="eggNOG" id="ENOG502SJIR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021980_0_1_1"/>
    <dbReference type="OrthoDB" id="1637350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047490">
        <property type="term" value="F:pectin lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF67">
        <property type="entry name" value="PECTIN LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936095" description="pectin lyase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="12">
        <location>
            <begin position="501"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="381"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="382"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="491"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK84044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="548" mass="56574" checksum="1E80AC4DC89A2E46" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C019</accession>
    <name>X0C019_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7908 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C019"/>
    <dbReference type="HOGENOM" id="CLU_008418_1_0_1"/>
    <dbReference type="OrthoDB" id="3563678at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057230">
        <property type="entry name" value="DUF7908"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25485">
        <property type="entry name" value="DUF7908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7908" evidence="2">
        <location>
            <begin position="146"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="517" mass="53496" checksum="3DF6D14FF4A725E2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C052</accession>
    <name>X0C052_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription regulator Rua1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C052"/>
    <dbReference type="eggNOG" id="ENOG502R0SR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018826_0_0_1"/>
    <dbReference type="OrthoDB" id="5595379at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028012">
        <property type="entry name" value="Rua1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125:SF3">
        <property type="entry name" value="TRANSCRIPTION REGULATOR RUA1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14616">
        <property type="entry name" value="Rua1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription regulator Rua1 C-terminal" evidence="2">
        <location>
            <begin position="412"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="609" mass="67995" checksum="643D2E386B728BE8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C170</accession>
    <name>X0C170_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Clavaminate synthase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C170"/>
    <dbReference type="eggNOG" id="ENOG502QRGK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045411_1_0_1"/>
    <dbReference type="OrthoDB" id="438224at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.330:FF:000033">
        <property type="entry name" value="Clavaminate synthase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420:SF1">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="39890" checksum="2D9A2A23A74532FE" modified="2014-05-14" version="1">MVAQAQAVSVSLQDLKDGNIPFETLKEAFGPDSLGILVVKDVPKEFPELRHQALSYASYLGNLPKEELEKLENARAKYLTGWSLGKETLKNGQVDTFKGSYYANCAFYIDPSLECAKPTEEFSIDTFPEYLAPNVWPPENVLPGFKPSVTSLCRLIIDVAVLVARACDRFAQEDIPGYPAGYLEHVVSTSSTTKARLLHYYPQENDPAANGGDEDDWCATHLDHGCLTGLTSAMFIDEHKTSPAVPEVTNLNGASLPPLDELPSSPDPSAGLYIKSRTGETVQVKIPRDCIAFQTGEALERITAGRFKAVPHFVRGVRASVSDGKIARNTLAVFTQPNLGEEVDIKQHLTFGEFARGIVDKNTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1P5</accession>
    <name>X0C1P5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1P5"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_15_0_1"/>
    <dbReference type="OrthoDB" id="566138at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005127">
        <property type="entry name" value="PRK06565.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF11">
        <property type="entry name" value="AMIDASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="686" mass="74191" checksum="5220F802670FB4F0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C210</accession>
    <name>X0C210_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA-directed RNA polymerase II subunit RPB9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_08287</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C210"/>
    <dbReference type="eggNOG" id="KOG2691">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093932_2_0_1"/>
    <dbReference type="OrthoDB" id="282270at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001193">
        <property type="term" value="P:maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase II subunit RPB9-like zinc ribbon" evidence="9">
        <location>
            <begin position="25"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK88460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="186" mass="20660" checksum="8154198B6F2ED76C" modified="2014-05-14" version="1">MATPQSTTSYEGAEGDKKLEQITFRFCSECSNMLYPKEDEDAHKLQFTCRTCQYTEDAKSTCVFRNVLNTSAGETAGVTQDVGSDPTVSHLPPVLCYGCGGVILCTSCGQPDCQMVVSNEKVSQPITGMCQFTLPWEDPFADYDEEMMDEDYDDTRTESDDFLSDASEEFLEEISMCCDSSMKCES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C277</accession>
    <name>X0C277_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C277"/>
    <dbReference type="HOGENOM" id="CLU_2306306_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="100" mass="11528" checksum="E429807E6351B353" modified="2014-05-14" version="1">MNRRTILLASTRNTKKPSYGRGTWLLGRLRISYNIDQQTDSPEQDQRKSLVFLCNAYPAVETGDFPRNCSARIRGLCWTVRDTVCEGCRKSETRVDQTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C344</accession>
    <name>X0C344_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Galactinol synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C344"/>
    <dbReference type="HOGENOM" id="CLU_049943_0_0_1"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="35158" checksum="2EA08980DD1B9CBA" modified="2014-05-14" version="1">MVSENTAALPPKVWATLVTNDDYLKGVLALNYRLRCVKSKYPLLVLYTSTLSQASVDCLKRRSIATFQVPRLAPTTGKEYTDDPRFNECWTKLIAFSLTDYSRIVLLDSDMLPLQNMDELMDLDLDLPAVSGSGDAVSSKRVFAACHACTCNPLRKPHYPSNWKPENCAFTSQHASPEVAQTTGADISTGLGKLNSGLLVINPSKAIFDQIVTKMNEAGLDYQFPDQDLLADVFKGRWVALPYIYNALKTMREPAVHGAIWRDDKVKNVHYILSPKPWDELGPDGTWKGDKPIHKWWIDAYKSMRAEEKTLGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5C7</accession>
    <name>X0C5C7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5C7"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_14_4_1"/>
    <dbReference type="OrthoDB" id="566138at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF37">
        <property type="entry name" value="AMIDASE C869.01-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936961" description="Amidase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="81"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="585" mass="63329" checksum="34C2CAD068ABC527" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6G7</accession>
    <name>X0C6G7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dynein intermediate chain, cytosolic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09582</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6G7"/>
    <dbReference type="eggNOG" id="KOG1587">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012999_2_0_1"/>
    <dbReference type="OrthoDB" id="366230at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010970">
        <property type="term" value="P:transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000414">
        <property type="entry name" value="Cytoplasmic dynein intermediate chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF22">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="508"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK86783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="692" mass="75522" checksum="70595B7EB41801D2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8Q5</accession>
    <name>X0C8Q5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP-binding protein EsdC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8Q5"/>
    <dbReference type="eggNOG" id="ENOG502QVY6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063252_1_0_1"/>
    <dbReference type="OrthoDB" id="5364946at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40625:SF2">
        <property type="entry name" value="GTP-BINDING PROTEIN ESDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40625">
        <property type="entry name" value="GTP-BINDING PROTEIN ESDC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="34336" checksum="4B5BA61143BC9BCD" modified="2014-05-14" version="1">MSAVQLSFSLRVSSGVKTVHLLGSWDGYVGQLPLSKDKSSSKSGSWKGTFRFQNSTLEAGQRYWYYYIIDGYHVAHNPSVTSTIEPTTGRELNVLDVPTDSHKSSSHRSSSSKSSSKSSSSSKSSSKSSSHKSSSSSKSSSHSSKDKESRSSRSSRHSSKLSVDIPKGRPLSISQIQAPKPMSPHATKHILDASYYDNEELEELADRFGSANIEDEFITDFSTSPISSSGSSLSYRSDSSSPNSSLSGYSTPGSDVSSCTCERYGITRKGERVKLDCGGSRCGYDDDSDSICSSGSEDEYEYEASVSRTSSRRHGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAK3</accession>
    <name>X0CAK3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAK3"/>
    <dbReference type="eggNOG" id="ENOG502SPNY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029638_0_0_1"/>
    <dbReference type="OrthoDB" id="5387895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="468" mass="53599" checksum="D892BBD2AF6D3620" modified="2014-05-14" version="1">MYPPSSRFSRLSLESMSPETRSRTRAQSLGRKTEQSHHDESSSDSDTSSDSSGYVDYSSEFDDDDEPSAIRSPTKLTYLVGHLPEETQSIVRDTFKEPPKIALEKCRRIDDTYAFQMTELVTRSVRIRAPQDGTSNLSCSCRDDGQPCQHLLWLLDQIVKQTLYETDLSKPLRMNPVGYAEEMGEVFQNISNFRLDVLAEGLHCHLVTPDSEYNNEPDAFRAQEAREMLSSVYKMDPGDFRPDIFEKVSHRRKIIKRNDLEQTISRMLLDNHHFFHYFRSLSRPQDPIKDVFYKLTQRINRVVRDLDTPGQTSDPDPPRDVIWAASHILGCVRRMRHDIYSRESPISAREALSAARSLVHILDLVVSRNTDHGPIDAPRIDRNLYLRLIGDRDQDFILNVLNLIPEAASQFLHNLEEVLGKIEIYGAPAGYVQRFRAMLGRLRTSSTGSGLKRSVQGQTGGRKTRRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CC20</accession>
    <name>X0CC20_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658449">
        <property type="protein sequence ID" value="EXK80197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CC20"/>
    <dbReference type="eggNOG" id="ENOG502SPEF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042066_0_0_1"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="52095" checksum="110B70BDA3C1AD49" modified="2014-05-14" version="1">MPQTGPSISPALGIRLEGDLHSYSPGDTIIGYVYRKSPVVSPDSSVTISLSGRTKSKIVIHRANSTSTYRGRFNLISESACSQKIFQGPLHIESGGDEQTWPFAITLPKHVDPRYLQGGGQDESFLPLGATDHILPSTYTLRSLGNTEGFIEYFVKATLRATGQGHVNMTEAVLPFNVINLSPDPPIADFALKGSWSRQTMSSYRLVPGMEDVKLSFSQKMKQSFSTSSVPEFFYNLIVDVPTVIQLDNPTPIPFKLRVVPDLNGTSEIIKEIPQKVKLSSVSIRIVSSTEVICEGTLYPHTKEKREEIDLCVESAIGRIKDDIYIPCTDEWPSLDIGDIIDLRLGQLRPGFPHRPGGGYVQFNPTFTTYNIRHSHRLTWKVIGEIAGERFSALGTVALKILMPSDERRRLGEKDSVQRAETEAASDGAPGPSQLQRNESWIQPPDEDDAPPSFTEVVQEDKGAHVAEKSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CC62</accession>
    <name>X0CC62_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CC62"/>
    <dbReference type="HOGENOM" id="CLU_3032420_0_0_1"/>
    <dbReference type="OrthoDB" id="4972297at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="55" mass="5622" checksum="62856CBC1B4E9B5D" modified="2014-05-14" version="1">MSFSNLCKVAPVDAKAPTTINTPVDMANPKCACSCGYNNIVKFTGVAKSDVALGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CC95</accession>
    <name>X0CC95_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_08121</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CC95"/>
    <dbReference type="HOGENOM" id="CLU_000604_21_1_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF464">
        <property type="entry name" value="ABC-TYPE TRANSPORTER CICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="142"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="106"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK88838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="400" mass="43695" checksum="E6079B9E3B0C2941" modified="2014-05-14" version="1">MHLIGCAVGTLAQFLPVLAIMIRFIVYAVVNGSLDPADVSSSLAILYVLRAPTNWLPVSLSLAADAFQSIKRIEDFLLAEEVQAQTVPDITLAPAVKLSNASFTWESPPANEEGESRKYEKKKNRMSRAMRRQRAGHEKKGIEASDTEVLPVRDSDAPFSLSDISLECQRGELVGIIGSVGSVKTSLLSVLAGDMRQTGRILQFAADRAYCPQYAWIQNASVRDNITFGKSLHQQLYSDVVHASALLPDFELLPYGDMTEIGERGVTLSGGQKQRINIARAIYSDAGIVLLDDPLSAVDAHVGTHIFNEAICGLLKDKCRFLATHHLHLLSRLDRIIWMVDGRIDAIGTYEELAESHPAFASLVAKGDSVGLDNTTTKAEVLMQEEAKIVDSVPFSVYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCQ3</accession>
    <name>X0CCQ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pheromone alpha factor receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCQ3"/>
    <dbReference type="eggNOG" id="ENOG502QTV4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035056_0_1_1"/>
    <dbReference type="OrthoDB" id="5402633at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038038">
        <property type="term" value="C:G protein-coupled receptor homodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004932">
        <property type="term" value="F:mating-type factor pheromone receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14939">
        <property type="entry name" value="7tmD_STE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.920">
        <property type="entry name" value="Pheromone alpha factor receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000366">
        <property type="entry name" value="GPCR_STE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027458">
        <property type="entry name" value="STE2_TM1-TM2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28009">
        <property type="entry name" value="PHEROMONE ALPHA FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28009:SF1">
        <property type="entry name" value="PHEROMONE ALPHA FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02116">
        <property type="entry name" value="STE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00250">
        <property type="entry name" value="GPCRSTE2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="380" mass="42257" checksum="E64CFEB5B4813197" modified="2014-05-14" version="1">MSTFDPFTQNVTFLAADGNTTISIPVVLVDEMRRMMVNTVINYATQLGACLVMLVVLLVMVPFSKFRRPFNALQIISLFICSCRMVLLCIWNISKFADFYPFWSHDFSHIPRSGYVPAIAANIISLLLVISIETMLMSQAWTMVKLWPNMWKYIIAGLSLVISLMTICVRIAFTAVQNKAVLDTIPPLHMLWLIKWTVIMNVSSISWWCAIFNIKLIWHLISNRGILPSYKTLTPMEVLVMTNGILMIIPVIFASLEWAHFVDFEAASLTLSSVAVILPLGTLAAQRIAASNANSAHSSGASSGIRYGASGPSSFTGFKAPSFSTNRSGATDRPHVSVYARCEAGTSSRDHINPEDVELGKIDSDHVRVDKAFLQREERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCR8</accession>
    <name>X0CCR8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08412</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCR8"/>
    <dbReference type="eggNOG" id="KOG0908">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_14_0_1"/>
    <dbReference type="OrthoDB" id="19690at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937105" description="Thioredoxin domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="15"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK88629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="161" mass="17252" checksum="0E93BD64ED06BAD6" modified="2014-05-14" version="1">METIYIVFGLLALFMIAQAVFADRSPIPETSGKVYKISAPSELESVLASNTHVVVDFYADWCPPCRAIAPVFSNLADAHASEGQLAFAKVNTDHVKDVAAKYGISAMPTFVFFENGVAKGVQVEGVKSRAVAFTKDGRVDRIRGADRGALEAVVKALASEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDX8</accession>
    <name>X0CDX8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05703</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDX8"/>
    <dbReference type="OrthoDB" id="431626at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056840">
        <property type="entry name" value="HEAT_IPO9_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF9">
        <property type="entry name" value="IMPORTIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25018">
        <property type="entry name" value="HEAT_IPO9_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="5">
        <location>
            <begin position="23"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK92620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1079" mass="119385" checksum="3B6B34B01258F16F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIU4</accession>
    <name>X0CIU4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bacteriophage T5 Orf172 DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIU4"/>
    <dbReference type="eggNOG" id="ENOG502RPP8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_494344_0_0_1"/>
    <dbReference type="OrthoDB" id="3511049at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053006">
        <property type="entry name" value="Meiosis_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 113 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094:SF1">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 113 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10544">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00974">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacteriophage T5 Orf172 DNA-binding" evidence="2">
        <location>
            <begin position="405"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK94350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="603" mass="69481" checksum="6580503AF4EE1406" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CK17</accession>
    <name>X0CK17_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CK17"/>
    <dbReference type="HOGENOM" id="CLU_3377176_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="34" mass="3857" checksum="1078B17855E9F301" modified="2014-05-14" version="1">MTISHGSAEHQLMMSKDWRKHGRQPLTGALLKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CL60</accession>
    <name>X0CL60_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CL60"/>
    <dbReference type="eggNOG" id="ENOG502SHIF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037656_0_0_1"/>
    <dbReference type="OrthoDB" id="4187949at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="397"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="104"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="475" mass="52907" checksum="E20389DD2D11ED8D" modified="2014-05-14" version="1">MSPSPSRSPPPASTPQPDESQLPKGQCRYILMIPELKGQRCGCMGFDHNKSLPGATCNCGHLSCFHVANADTPTPSTNKSEIDAIQQRVRALEELANPQDRDRLSHVVRRISELEETVEKNKDETDTELKGSYRNASAAWALVTQLQQHIKSLEQTLRSQGEQLARTGSEVDDLRNRQLELLDSDECLEERIEKLESAEPLLSPPQDPDPSDATVNTFHLSPTTTVPSQLPLNSTHSLSIEHTASTERPRSWTVHVSLMPSKDTPFPFEKDTTSYKRCLSRGLHRMLAVEGDDAKSVTEAVSRAFEPLLKGRPWVPLQAKLCDAERLQGLPMLRPLEPRLIHGPYDRAFLKQHCAVLDASGKMDSLYIAMEHDSLSWNFLKRSPVYLDGLESAWERDSVLDKKDEQDPSSRDHHGDEGDESPPAGNIVGALTGLKRSMSEISCSSLDDTELPLAKLPRTCKTSQLEMRRGVETAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLX6</accession>
    <name>X0CLX6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_06493</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLX6"/>
    <dbReference type="eggNOG" id="KOG1167">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_118_2_1"/>
    <dbReference type="OrthoDB" id="10020333at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14019">
        <property type="entry name" value="STKc_Cdc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF23">
        <property type="entry name" value="CDC7 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="116"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="312"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK91829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="498" mass="57577" checksum="3E133DC149B92E84" modified="2014-05-14" version="1">MSAVVHQHVEEHFDIHEDLRTEDTEMMAEEERTEEAAPIDEDEHVQSFQQAHQQQHMQQMQHQQHAHRQPQQPQEEPQEEEEEEEEEESEDEAVDRTVQADMDKLQNDFPGFRNRYRLIKRIGEGTFSTVYKAEDIMYDHYDNSWDYEEDSSKWTPPPKATDSPVSHRPRRKARYVAIKKIYVTSSPSRILNELELLHDLRQCPSVCPLITAFRETDQVVAILPYFRHGDFRTYFRDLTITEISVYLRELFTALKSVHDHKILHRDIKPTNFLYDPGTQRGVLVDFGLAEREGSDAKPCLCHESREVRKHRQTNSVWAQNAATPQAGYPKSDTRSSRRANRAGTRGFRAPEVLFKCTEQTTSIDIWSAGVILLTILSKRFPFFNSADDVEAMIEIATIFGTKRMKAAGLLHGCVFETSIPTVGQGGFSMEKIIMWSTCRGEEKPLTGEEKLAINFLEWCMELDPGRRITAAEALNHDFLLLGEIEVERQENEQAMAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP66</accession>
    <name>X0CP66_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription elongation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_03177</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TFS-II family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP66"/>
    <dbReference type="eggNOG" id="KOG1105">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037637_1_1_1"/>
    <dbReference type="OrthoDB" id="44867at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001139">
        <property type="term" value="F:RNA polymerase II complex recruiting activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031440">
        <property type="term" value="P:regulation of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13749">
        <property type="entry name" value="Zn-ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000001">
        <property type="entry name" value="Probable Transcription elongation factor S-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.30:FF:000003">
        <property type="entry name" value="Transcription elongation factor S-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035100">
        <property type="entry name" value="TF_IIS-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003617">
        <property type="entry name" value="TFIIS/CRSP70_N_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006289">
        <property type="entry name" value="TFSII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01385">
        <property type="entry name" value="TFSII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF0">
        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006704">
        <property type="entry name" value="TF_IIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00509">
        <property type="entry name" value="TFS2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="12">
        <location>
            <begin position="7"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="13">
        <location>
            <begin position="148"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="11">
        <location>
            <begin position="265"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="88"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK95971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="307" mass="33963" checksum="C82D5ABF11BE6988" modified="2014-05-14" version="1">MPMDERELGQRIKALTKCVAANEPPENAIKLLETLKKDASPTEEMLRATRAGVFVGKLRSNSNKDIARAAAELVNKWKKLVEQEKHSKLRAKVGSGSPAPAPSSAPASSPAPPPPSSAGASGAKYKGDIEKRKYETDNVNVKRTDSSVRNSCIGLIYNGLAYRSTATENDVITRAVAVEHAAYTKFKGETPDYKKKIRSLFTNLKNKSNRELGRSVLSGEITAEKFVIMTDDELKSEEQRKKELELEKENMKKAQVPMAEKSISESLECGRCKKKQVSYTQAQTRAADEPMTTFCECMACGHRWKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQZ2</accession>
    <name>X0CQZ2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQZ2"/>
    <dbReference type="HOGENOM" id="CLU_038189_0_0_1"/>
    <dbReference type="OrthoDB" id="3481585at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="501" mass="57001" checksum="0CA7AB86AB8B5DFC" modified="2014-05-14" version="1">MEYETPTPLRTGSATVDPTRTSITILSTTPAVIHSYSKLNTSFTLINSTGFRSISGQSSNGAKRTYRSIIKEPQLTDRHYIERLLALECVPEYGGPPLLFTNWHDKPLWNDCNLLATRWACAGCLRLLPYYHFQYKFLAEVIWRKPMLGTPATKTITSWEPTNTPTGGVATTPPADGGGSIQARYNLIVGDILATPPFVLLGQYRAHGLAYFNGITFIDFRQRIIETPNDIRQRLWWNMTLMQNSEFGSNRHYRKCNGCLFKNGVFNDATITSHNGIYGTESFPIISIENHMISSPLDRYFPGILDTMQQGRPFKRFYQGFRKPWTLWMARCPRCEKWQELRAFRIGAGAGEVAGGRPGLEAWEPTMGRLTWDGVILTQEVFEKAYCNACFVAENDRHALAEYLGRWFVFLVEQQPHDVQSELLHEAGKFPRNSGALIDGNKVTAWNWQILDIHFLRCSGQSPWHLSSCFQSLYKDWLDICGENGHAFLDNPNIGSHMQYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR71</accession>
    <name>X0CR71_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR71"/>
    <dbReference type="eggNOG" id="ENOG502SE8I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021652_0_0_1"/>
    <dbReference type="OrthoDB" id="4332097at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="593"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="314"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="395"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="701" mass="78583" checksum="D972DEAC14560E78" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRM4</accession>
    <name>X0CRM4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transformation/transcription domain-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02417</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. TRA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5570127at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05163">
        <property type="entry name" value="PIKK_TRRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046807">
        <property type="entry name" value="Tra1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046805">
        <property type="entry name" value="Tra1_ring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF1">
        <property type="entry name" value="TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20175">
        <property type="entry name" value="Tra1_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20206">
        <property type="entry name" value="Tra1_ring"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAT" evidence="6">
        <location>
            <begin position="2669"/>
            <end position="3226"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="5">
        <location>
            <begin position="3505"/>
            <end position="3848"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="7">
        <location>
            <begin position="3845"/>
            <end position="3877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="163"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2030"/>
            <end position="2055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3235"/>
            <end position="3334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="3243"/>
            <end position="3262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="3313"/>
            <end position="3329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK97095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="3877" mass="443375" checksum="026D37ED52C81425" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSH5</accession>
    <name>X0CSH5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSH5"/>
    <dbReference type="HOGENOM" id="CLU_028627_1_0_1"/>
    <dbReference type="OrthoDB" id="1911848at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542:SF3">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="162"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="501" mass="55865" checksum="2F8299CFA21A4864" modified="2014-05-14" version="1">MEVLGAIVGCTSLALDIFNFATAELEGRGIDSLVLSLKHDVALLKDFARIFNAAAQSEQIPLTDKFLLNEICLALQPSLARIHSTIVRRKMSALTASPARKAVDKVHGFLYGKAEMQGISKDLFQWTERYHVRFGLLPVGLQTRLLAQGTDESLPGDIKALRETFRRLTDRSRSTVVDGLRKSEGMVTLRPGRPSSRMFATMNQRTVIVEFKEHSLSPSVTYMNDFETDVADLAKLLSGTDPLLCRTLKGEGYFHHPSRSAFAFIYQVPKLVVIPDDVTRPTTLLDLIMATRPALSKSGQIELIPPKHALEQRFELARKITSAVMYVHVMQYVHKSIQTSNIVMFAKNDSSPANTEQFPKVLGEPFLCGFETSRYDRGASDGQGDVEWGYNIYRHPKRQGLHPQSRYTMNHDLYSLGVVLLELGLWRPLTAMGLRDPNSVNGSVKDHLKKLAISGLPIMMGTKYRDVVLFCLDIDGDGQISNSTAVEEVLKKVEELAIGMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTI4</accession>
    <name>X0CTI4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_02666</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SDE2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTI4"/>
    <dbReference type="eggNOG" id="KOG2827">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060603_0_0_1"/>
    <dbReference type="OrthoDB" id="547031at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051421">
        <property type="entry name" value="RNA_Proc_DNA_Dmg_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053822">
        <property type="entry name" value="SDE2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024974">
        <property type="entry name" value="Sde2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786">
        <property type="entry name" value="SPLICING FACTOR SF3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786:SF1">
        <property type="entry name" value="SPLICING REGULATOR SDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22782">
        <property type="entry name" value="SDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13019">
        <property type="entry name" value="Sde2_N_Ubi_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sde2 ubiquitin" evidence="10">
        <location>
            <begin position="6"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="SDE2-like" evidence="11">
        <location>
            <begin position="90"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="166"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="210"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="266"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK97481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="282" mass="30903" checksum="676DF5CD53C43049" modified="2014-05-14" version="1">MSPRNVNVLVTSFAGLGLPPTLVLPLASSTTVTELRERIDDRLPTTQSRLILTTLSNKQLPASSDSPISSYLSTAHDEFLSLRLAVPLCGGKGGFGSQLRAAGGRMSSRKKKSQEDHGSSRNLDGRRLRTVNEAKALAEYLAIKPEMEKKEKEKRRERWEQIVQMSEQKEAEIKSGSKSRLDGQWVEDKEESSERTREAVLAAMKAGNYKDNLLGTSHDSSSTQPSNDQSGSDEDKGTSSEQSTPPPAEGAKADKGKGKATTFFGFDEDDEFMSSDDEDEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU84</accession>
    <name>X0CU84_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Myotubularin phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_03665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU84"/>
    <dbReference type="eggNOG" id="KOG1089">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001839_5_1_1"/>
    <dbReference type="OrthoDB" id="271628at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004438">
        <property type="term" value="F:phosphatidylinositol-3-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030564">
        <property type="entry name" value="Myotubularin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010569">
        <property type="entry name" value="Myotubularin-like_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807">
        <property type="entry name" value="MYOTUBULARIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807:SF128">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06602">
        <property type="entry name" value="Myotub-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51339">
        <property type="entry name" value="PPASE_MYOTUBULARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myotubularin phosphatase" evidence="5">
        <location>
            <begin position="136"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="677"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="702"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="740"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="681"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate" evidence="2">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="345"/>
            <end position="346"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="409"/>
            <end position="415"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR630564-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR630564-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK94878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="774" mass="87075" checksum="9C52F58BC77CD9C0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU98</accession>
    <name>X0CU98_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">L-iditol 2-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_01066</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU98"/>
    <dbReference type="SMR" id="X0CU98"/>
    <dbReference type="eggNOG" id="KOG0024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_5_1"/>
    <dbReference type="OrthoDB" id="5363962at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF25">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="9">
        <location>
            <begin position="13"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK98030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="380" mass="40884" checksum="25C9B163EE6982C9" modified="2014-05-14" version="1">MATERVKASVLHGEKDLRLEERELPAPSSNEVQVAVKSTGLCGSDLHYYNHFRNGDIIVREPLTLGHESAGTVVAVGSDVTHLKPGDHVALEVGLPCEACELCGEGRYNICRGMKFRSSAKANPHAQGTLQERINHPAKWCHKMPEHVTLDLGALVEPLSVAMHARDRAALPKGSTVLVLGAGAVGLLAAAVAKADQAKTVIIADILKDRLDFAINNGFADASVVVPMERPQTIEDKLAFAQKVAAMVKETQVNGEAVGEVTAVYECTGVETCVQTAIYATKPGGKVMIIGMGTPVLTIPMSAAALREVDIVGVFRYANTYKEIIELLANPPANMPDVSRLVTQRYKGMENIEEAFKMAGKVRDEQGNLVIKVVVDFNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV41</accession>
    <name>X0CV41_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">DNA 5'-3' helicase</fullName>
            <ecNumber evidence="19">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">FOQG_10001</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the helicase family. RAD3/XPD subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="19"/>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV41"/>
    <dbReference type="HOGENOM" id="CLU_011312_1_0_1"/>
    <dbReference type="OrthoDB" id="272481at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045951">
        <property type="term" value="P:positive regulation of mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.40:FF:000001">
        <property type="entry name" value="DNA repair helicase (Rad3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.20:FF:000001">
        <property type="entry name" value="DNA repair helicase rad15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000135">
        <property type="entry name" value="DNA repair helicase RAD3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000128">
        <property type="entry name" value="Putative DNA repair helicase RAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000381">
        <property type="entry name" value="TFIIH basal transcription factor complex helicase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.20">
        <property type="entry name" value="Bacterial XPD DNA helicase, FeS cluster domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010643">
        <property type="entry name" value="HBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001945">
        <property type="entry name" value="RAD3/XPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042493">
        <property type="entry name" value="XPD_DNA_FeS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06777">
        <property type="entry name" value="HBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00852">
        <property type="entry name" value="XRODRMPGMNTD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="21" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 24" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="17" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0804">Transcription</keyword>
    <keyword evidence="13" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="23">
        <location>
            <begin position="7"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="755"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="21">
        <location>
            <begin position="255"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="22">
        <location>
            <begin position="775"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EXK86357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="789" mass="91071" checksum="2B5307CF277F9C41" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVJ8</accession>
    <name>X0CVJ8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVJ8"/>
    <dbReference type="eggNOG" id="ENOG502SAE9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016938_1_0_1"/>
    <dbReference type="OrthoDB" id="5350396at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="633" mass="71050" checksum="930494754097FC6C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVR4</accession>
    <name>X0CVR4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVR4"/>
    <dbReference type="HOGENOM" id="CLU_2291801_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="101" mass="11220" checksum="49003AFA9A54A32C" modified="2014-05-14" version="1">MRFLFMEIFPLSSVSLGTSIINGLVLLSLVMFSPSSPTPLTVPERRDMRAEPGRTRPEGPCKPPAPKQKKLRMRCDARLRVVPPQGQAESPHSLTFGLHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CW28</accession>
    <name>X0CW28_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_01298</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CW28"/>
    <dbReference type="eggNOG" id="ENOG502S3II">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052684_0_1_1"/>
    <dbReference type="OrthoDB" id="4205486at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029208">
        <property type="entry name" value="COX14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14880">
        <property type="entry name" value="COX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="236"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK98366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="272" mass="30255" checksum="56DC94BC2282F510" modified="2014-05-14" version="1">MASRMGPRSVKDATRFTSTIPHATSKAAQRTPRIPGETPEQRVRRLRQAHLAAQHASISKTDKFIDASRRIFDVAHRWTVGSIVVFTVVAAVVSGYSVWDMIRYNRARRAEWVEAQKLLEADELAMARLAYIKGEATEEQILLVEEANQAAEARGEKLPPLLEAPSHRTHFEEHIKPTFKENTEENVTKPSSGKGVLGIFSGVLGGGEKKEESTQGLQDYQTQSVESGAVKVRLEEAMAAERERQQNGGPLDRLGVEPPAGSTPSKSWWKFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CW68</accession>
    <name>X0CW68_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 12">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_04115</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 12">Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Vacuole membrane</location>
            <topology evidence="1 12">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the beta-catenin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CW68"/>
    <dbReference type="OrthoDB" id="7537227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000011">
        <property type="term" value="P:vacuole inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000243">
        <property type="entry name" value="Putative Vacuolar protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000095">
        <property type="entry name" value="Vacuolar protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="7" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0926">Vacuole</keyword>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="87"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="128"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="169"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="210"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="253"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="294"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="335"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU369097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK95553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="574" mass="62377" checksum="DF7B5D31AD4A4F31" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CW78</accession>
    <name>X0CW78_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase S59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_01530</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin GLFG family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="MEROPS" id="S59.A07"/>
    <dbReference type="HOGENOM" id="CLU_002330_0_0_1"/>
    <dbReference type="OrthoDB" id="3797628at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034398">
        <property type="term" value="P:telomere tethering at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1610.10:FF:000003">
        <property type="entry name" value="Nucleoporin SONB, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1610.10">
        <property type="entry name" value="Peptidase S59, nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037665">
        <property type="entry name" value="Nucleoporin_S59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007230">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036903">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021967">
        <property type="entry name" value="Nup98_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198">
        <property type="entry name" value="NUCLEOPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04096">
        <property type="entry name" value="Nucleoporin2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12110">
        <property type="entry name" value="Nup96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82215">
        <property type="entry name" value="C-terminal autoproteolytic domain of nucleoporin nup98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51434">
        <property type="entry name" value="NUP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase S59" evidence="12">
        <location>
            <begin position="880"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="426"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="545"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="692"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="773"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="862"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="441"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="461"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="481"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="545"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="830"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="865"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK98730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1937" mass="204846" checksum="19D8865128D79C9D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWB2</accession>
    <name>X0CWB2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWB2"/>
    <dbReference type="HOGENOM" id="CLU_3392321_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3339" checksum="B5C306ACFF469CC2" modified="2014-05-14" version="1">MESAANSQKVLASAHYRSGVGEGPCTRGQQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-09-13" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXI1</accession>
    <name>X0CXI1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXI1"/>
    <dbReference type="HOGENOM" id="CLU_013985_13_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="246" mass="27718" checksum="F8B41859F3DB32C7" modified="2014-05-14" version="1">MANQFSFHDASTSFNDAQFMADAMDSTIPHLVAAGNAGQWGTEPLSRKESFMQKMHDAVSKSEQFCETGAGDRERIFIAEVEDDQTSSGSTANGNLSRRVDENGKSFVSVGFVKIVEEQFVSYLKETESLKAQIEPALKKGKFVFLQYLVTDHRVGDRRRGAGAALLQKVKDYTLERGWKTIWLDCWDGGNGQLVQYVPRRTPSTRFIFNGYRYYVDQGFHIMGSFGNDHDDGSSWNGKLFRMDMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY32</accession>
    <name>X0CY32_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY32"/>
    <dbReference type="eggNOG" id="ENOG502QZZN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1372273_0_0_1"/>
    <dbReference type="OrthoDB" id="5034114at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="199" mass="22964" checksum="60B8F7D9F0121F39" modified="2014-05-14" version="1">MPNQRVPDEEARMIAKIYSTDFYRKVSDLARNPSGTVYDPTMGPPPPSPAFKEFRPMPPSSQAPRPDTPRPEDHYGAGMIIPGKAVVNDNWEENLRRVIGPNYGGYRWKSLGDMTMRCWQHVREKGNRTQRGTKWSMDEIERYGRLSVWGVHKDVIGALMGWPVNPQWTREEEDHFEAAVQDELSKNPMKNSERHTIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYR5</accession>
    <name>X0CYR5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ubiquitin C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_01845</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ubiquitin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYR5"/>
    <dbReference type="eggNOG" id="KOG0001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010412_7_0_1"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000016">
        <property type="entry name" value="Polyubiquitin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000004">
        <property type="entry name" value="Polyubiquitin Ubiquitin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="77"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="153"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="229"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK99281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="305" mass="34285" checksum="D634409084EF0BB9" modified="2014-05-14" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0K8</accession>
    <name>X0D0K8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_02413</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0K8"/>
    <dbReference type="OrthoDB" id="2420415at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02666">
        <property type="entry name" value="Peptidase_C19J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025305">
        <property type="entry name" value="UCH_repeat_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13446">
        <property type="entry name" value="RPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="607"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="713"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1221"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="724"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="760"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1244"/>
            <end position="1257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK97088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1270" mass="142347" checksum="CDAEC26D9BB3C4BB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D178</accession>
    <name>X0D178_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_00674</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG101 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D178"/>
    <dbReference type="eggNOG" id="KOG4493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069661_1_0_1"/>
    <dbReference type="OrthoDB" id="10259639at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012445">
        <property type="entry name" value="ATG101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292:SF0">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07855">
        <property type="entry name" value="ATG101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXL00536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="215" mass="24585" checksum="CDB7BE8D0C3CA1F8" modified="2014-05-14" version="1">MIIAHNRLYNSTDNMDQQEPPEFILDVFADPRSVREVVKGILHTIFFNRFFPSIVPQTREVLDTTLPYVDDDELETMIDQRVAALERQIDVQRSSGGANSASIGSGNGGRGQLVVQFFEKRRRKAWLSRGDEEVCWECWTIKVTVAEPRTESERAKVRRAMEQTLSATAMKIVAFVNTHKDHIPPITTQGTNPFPYKINIDQKEAAGWATRMRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1M8</accession>
    <name>X0D1M8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08379</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1M8"/>
    <dbReference type="HOGENOM" id="CLU_2638163_0_0_1"/>
    <dbReference type="OrthoDB" id="10279325at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="87" mass="9554" checksum="AB79A04E6D83BE57" modified="2014-05-14" version="1">MTLDSSESSYMINVSSVFDPNTNAEFHRVLQSTIKGSSEWDSDVQEDSDTMERAPSRCSTKIQCRGLFNLADSEGGEKVEGSTGRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0D227</accession>
    <name>X0D227_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D227"/>
    <dbReference type="eggNOG" id="ENOG502RJ9U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1001329_0_0_1"/>
    <dbReference type="OrthoDB" id="5094920at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="278" mass="31393" checksum="11E73E132339DFC6" modified="2014-05-14" version="1">MPDSNMTSHDGSASCFAFPAPLTALTFFNSDLTDSVLLSDEGFISDDDDPDDEFSVPLTYLTTFPVERFLSPLPESRSTSTSSMSPEPNCSSQYGLSESDPDIGNTEPQMKYPDHDCLSSGSSSSSSESDDDSDILASSRRCFQEGNSPNKPLRTQTIVSPTPRLNTETFSEPDSDLPSYHVHQLDWNQPVHVGKLRKRSDQHNREIKALVWDTYHIFIPTDIPGSSRYRTELKDWRRLRREYIMNKPTAQQQARSQRLLLALSDLIKKRNSFFGKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2P3</accession>
    <name>X0D2P3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2P3"/>
    <dbReference type="eggNOG" id="KOG1470">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016665_3_0_1"/>
    <dbReference type="OrthoDB" id="43460at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052432">
        <property type="entry name" value="PITP/CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="3">
        <location>
            <begin position="314"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK97828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="586" mass="66253" checksum="8BF7FABE83C3FC10" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3P7</accession>
    <name>X0D3P7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable beta-glucosidase btgE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Beta-D-glucoside glucohydrolase btgE</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Cellobiase btgE</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Gentiobiase btgE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_07930</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3P7"/>
    <dbReference type="eggNOG" id="ENOG502QS0R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027285_2_0_1"/>
    <dbReference type="OrthoDB" id="4082933at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF24">
        <property type="entry name" value="FAMILY 17 GLUCOSIDASE SCW11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0134">Cell wall</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938183" description="Probable beta-glucosidase btgE" evidence="14">
        <location>
            <begin position="20"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="250"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK89277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="610" mass="65511" checksum="611205D3D4DC24BE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3U2</accession>
    <name>X0D3U2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3U2"/>
    <dbReference type="HOGENOM" id="CLU_3014250_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="56" mass="5955" checksum="C68B4D8389111F2C" modified="2014-05-14" version="1">MKEGSGLWPVTAATHRHSVSVVVNPEDAVPASLHICIRLSPETEIYRVIGSVVTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3Z1</accession>
    <name>X0D3Z1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3Z1"/>
    <dbReference type="HOGENOM" id="CLU_007003_1_0_1"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="40"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK98278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="683" mass="78122" checksum="C31A55CDF86D02BB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5G8</accession>
    <name>X0D5G8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_07371</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5G8"/>
    <dbReference type="HOGENOM" id="CLU_072377_0_0_1"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="PITH" evidence="4">
        <location>
            <begin position="135"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK89892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="36020" checksum="8F931BA02F3CCDB0" modified="2014-05-14" version="1">MSQNSVVTIDSKRHFDSVLKSSRIVIADFYADWSDSSNQIAPIYERFAKDVAQPNLITLVKVNSDNQPELSQEYKITDLPTFIVFADGKQVDQVQGADPQKLRDTLMKIPALAASLNEKTARENAGSASGGPSWKGMEAPRGYNDITDQIELRDLEVLNADENAGTVRVLFDGSKPSGLGNSKGTSKDYVQSGADDQLLLYIPFQSIVKLHTLQLTSLPPKDDEDVMRPGNIHLYINRTHNLDFNEADDTEPTQAIEISPEDWNEEGTVSLSLRYVKFQKTSSLVIYVQQGEGDGETVRLDRVRLIGEAGAKREMGKLQKVGEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5U5</accession>
    <name>X0D5U5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_01659</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5U5"/>
    <dbReference type="HOGENOM" id="CLU_008455_11_5_1"/>
    <dbReference type="OrthoDB" id="3561359at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140115">
        <property type="term" value="P:export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000082">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF7">
        <property type="entry name" value="DRUG_PROTON ANTIPORTER YHK8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="416"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="98"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK98938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="453" mass="50024" checksum="A5A02B5CF157B56D" modified="2014-05-14" version="1">MSNMDRDIEKTSTNSGTLGPERNDTTFATIQSPQAIRTRSRASASISRCQSQNGYSCNPHNEPSDDEVEKDPFEVGWDGGDNDSLCPRSFHNMKKWLIIIIVSSGSLCVTAASSIYTSTYGQMEDEFGNSREVSILGLSFFVLGIGLGPMFLGPLSEFYGRRLIYVVSWTLYVIFIIPQAVAQNIETVIVSRFLDGFAGSAFLAVSGGTVGDLFTANELQAPMLMFSLAPFVGPSIGPLIGGFINYNTDWRWTHWTLLIWAFVLLLGIVFLVPETYHPILLKNKAKQMRKETGDGRWKAPTEKVQKSATSAIGRSLLRPFQLLIFEPMCLNLCIFTAIVLGILYLFFGAFHLVFGNIYGFNLWQNGCSFLGILVGMLLAAGLDPLWHNIRNKLIRKLSEETGVEGNSQPEFRLPPAILGGILVPVGIFMFAWSCYPRVHWIVPIVGSAIFGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5Z4</accession>
    <name>X0D5Z4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisomal targeting signal receptor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Peroxin-5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_07470</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxisomal targeting signal receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5Z4"/>
    <dbReference type="eggNOG" id="KOG1125">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10006023at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005052">
        <property type="term" value="F:peroxisome matrix targeting signal-1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000218">
        <property type="entry name" value="Peroxisomal targeting signal receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024111">
        <property type="entry name" value="PEX5/PEX5L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130:SF0">
        <property type="entry name" value="GH08708P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0882">Thioester bond</keyword>
    <keyword evidence="9 15" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0832">Ubl conjugation</keyword>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="348"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="459"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="501"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="214"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK90067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="638" mass="71221" checksum="C4F23A4FD227D3B0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6P0</accession>
    <name>X0D6P0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="6">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_07130</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="6">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="6"/>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6P0"/>
    <dbReference type="SMR" id="X0D6P0"/>
    <dbReference type="eggNOG" id="KOG0557">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_2_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000003">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006257">
        <property type="entry name" value="LAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01349">
        <property type="entry name" value="PDHac_trf_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="36"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="9">
        <location>
            <begin position="179"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="129"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK90312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="457" mass="48774" checksum="50117BF3905D458F" modified="2014-05-14" version="1">MLSAALRRRVLAPTHSALRTGFAAHVVRHYASFPEHQVIKMPALSPTMQAGNIGAWQKKPGDSIAPGDVLVEIETDKAQMDFEFQEEGVIAKILKDAGEKDIPVGSPIAVLVEEGTDISAFEKFSIEDAGGDAAKPAAPKKEEKSESKSESASAPEPTPEPQQYQSQGRLQTALDRLPNISASAKRLAREKGISIDGLKGTGKNGQITEEDVKKAISSPAASSAPSATYEDIPISGMRKTIANRLVESTQTNPHFYVTSSISVSKLLKLRQALNSSADGKYKLSVNDFLIKAIAVASRKVPQVNSSWRDGNIRQFNNVDVSVAVSTPTGLITPIVTGVEGRGLEAISSQVKSLAKKARDGKLKPEEYQGGTISISNMGMNPAVDHFTAVINPPQAAILAVGTTKKVAIPAENEAGVEFDDQITLTASFDHKVVDGAVGAEWLKELKQVLENPLELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9E9</accession>
    <name>X0D9E9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CWH43-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00181</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9E9"/>
    <dbReference type="HOGENOM" id="CLU_050573_0_0_1"/>
    <dbReference type="OrthoDB" id="10032492at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050911">
        <property type="entry name" value="DRAM/TMEM150_Autophagy_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324:SF2">
        <property type="entry name" value="EG:22E5.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324">
        <property type="entry name" value="FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="7">
        <location>
            <begin position="9"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="261"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK99764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="300" mass="33964" checksum="706D8752EF70CBCD" modified="2014-05-14" version="1">MAVKGIFSYWWFPVISGLVWLGMLLGLLLEWQVNQHGRRYPTQSIHSDIAYISNVGADRLQPLFIVGCVLTSIFLDAAFLSERWLRHRGRLVPNTTLMEKILSGLSIAFATVGTVGLICLSIFKTGKYSRLHNTFLALFIGGYLISAVFICWEYQRLGISESSLFNGHANLTNKPLDYREHRILRMSFWVKLTFILVELFLIIAFGVCSRVKKRNAAAILEWVISFIFTFYAISFVIDLYPAVRTKSPDARYQKSYYMPSALSDSTSPSNGSRSNFDAAANGRTDVEMAQNGNRVPPRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0DC22</accession>
    <name>X0DC22_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_00952</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DC22"/>
    <dbReference type="MEROPS" id="T01.978"/>
    <dbReference type="eggNOG" id="KOG0183">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_4_0_1"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03755">
        <property type="entry name" value="proteasome_alpha_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000004">
        <property type="entry name" value="Proteasome subunit alpha type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 3 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="238"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXL01089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="269" mass="29206" checksum="BBD4DE6256C635B6" modified="2014-05-14" version="1">MASGYDRALSVFSPDGHVFQVEYAGEAVKRGTCAVGVKGADVVVLGCEKRSAMKLQDTRITPSKIQLLDHHVALAFAGLNADARILVDKARLEAQSHRLSVEDPVTIDYITKYVAGVQQRYTQAGGVRPFGISTLIVGFDNGSDVPRLYQTEPSGIYSAWKANAIGRSSKTVREFLERNYKEDMDREATIRLAIKSLLEVVQTGAKNIEISLMAPGATIETLPTSEIEGYVKEIEQEKQEEAAKKKTGRTPGTGSAAILTRSQDDSAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0DLK6</accession>
    <name>X0DLK6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI anchored serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DLK6"/>
    <dbReference type="eggNOG" id="ENOG502RN1I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1396437_0_0_1"/>
    <dbReference type="OrthoDB" id="5105046at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936924" description="GPI anchored serine-rich protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="19697" checksum="FB5C949A7771FF13" modified="2014-05-14" version="1">MQFSSIMIAAAGASVAAAQGYAPPAPVLDTTTLTSTTTRVITLTQCNPTVTNCPLRTTTSTEVVVTTSTAAPEVPTTSVYVPPTTSVYEPVVNTTSHELPTIISTPTISTTKKAPSAKTTFYPAGNTTTKAGPTAPGSYTTTKLPVPGSSTDVPANPGKPGYEAPSPSTVPTAGASGLIASSGFVGAAMVAAMVALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0DM51</accession>
    <name>X0DM51_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DM51"/>
    <dbReference type="eggNOG" id="ENOG502SN8S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021768_5_0_1"/>
    <dbReference type="OrthoDB" id="5598852at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="50"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="296" mass="33966" checksum="E9998FA8DD1C8E69" modified="2014-05-14" version="1">MASLSEAEQERPEAMESEIEDSEHDTLPKYLKCSYFDAVIGNEIHNYWGNRVLEHTNSNGEVLALKVSSPDGIDRSQANMMHYAATHGVLAPKVRGVYDIVTKRPIARVMVSERVPGVPLVDVWQAMSEDEQRSIKGQLRLQVQHMRTLVQPYIGRINRQPTRNIYNTTFIRHCGPFEDEEAFDNWCLDRLSGGTIQHWRWKKVLERQRRKSTGRFVLTHGDLSPRNIMVDGSTITGIIDWESSGFYPEYVEFAFAIGIGPGMEEWWIPVLKEVLEPCSSEMVKFTGLIEERMSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0DNH9</accession>
    <name>X0DNH9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2079">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="289913at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059070">
        <property type="entry name" value="TPR_VPS8_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025941">
        <property type="entry name" value="Vps8_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23410">
        <property type="entry name" value="Beta-prop_VPS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12816">
        <property type="entry name" value="TPR_Vps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25066">
        <property type="entry name" value="TPR_VPS8_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 8 central" evidence="3">
        <location>
            <begin position="728"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="domain" description="VPS8-like TPR-like repeats" evidence="4">
        <location>
            <begin position="1270"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1499"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="113"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1511"/>
            <end position="1530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK95897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1596" mass="176315" checksum="E9F4B4376F38C863" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0DQA1</accession>
    <name>X0DQA1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acyl-CoA synthetase family member 3, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03503</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DQA1"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05941">
        <property type="entry name" value="MCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF28">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="499"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK96487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="65124" checksum="0839CAE944E5C0ED" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0DR71</accession>
    <name>X0DR71_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTF2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DR71"/>
    <dbReference type="eggNOG" id="ENOG502ST13">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112120_0_0_1"/>
    <dbReference type="OrthoDB" id="25408at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTF2" evidence="1">
        <location>
            <begin position="16"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="169" mass="18881" checksum="7DEC3AF491EDE204" modified="2014-05-14" version="1">MSAPTLATEVQTSSDAAEIFTSNYYQAINRQNNILPFYINSSQRYPIAADISINGAVLPTPADYSKLLEAQGKDAHYEIESFDAHVLNPNFTMGAPENIFDSAKKEKNGDKMSILVTVMGRVQFGKGREAPQKMFNETFVLVPNWESMVKNPPKGVKKWLVMSQNFRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0DS53</accession>
    <name>X0DS53_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DS53"/>
    <dbReference type="HOGENOM" id="CLU_3260580_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="42" mass="4445" checksum="422CE0D800E74007" modified="2014-05-14" version="1">MVREMRSGGGGGLLLIESIPAGAHLEGAEKQPEILILSEKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0DU88</accession>
    <name>X0DU88_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">dihydrolipoyllysine-residue succinyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_02847</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="5"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DU88"/>
    <dbReference type="HOGENOM" id="CLU_016733_0_1_1"/>
    <dbReference type="OrthoDB" id="5391403at2759"/>
    <dbReference type="UniPathway" id="UPA00868">
        <property type="reaction ID" value="UER00840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033512">
        <property type="term" value="P:L-lysine catabolic process to acetyl-CoA via saccharopine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000006">
        <property type="entry name" value="Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050537">
        <property type="entry name" value="2-oxoacid_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004309">
        <property type="entry name" value="PRK05704.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416:SF5">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="14">
        <location>
            <begin position="41"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="116"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="123"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK97797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="430" mass="47259" checksum="5C8C1AAD58D8F5F4" modified="2014-05-14" version="1">MLSRSIATAARMVPATRALRPRSHPLVMLPSMMQTVRTYADSVIKVPQMAESISEGTLKQFSKSIGDYVEQDEEIATIETDKIDVAVNATESGTIKEFLVAEEDTVTVGQDLVRIELGGAPSGDKKEAPKEESKEQPQKSESESKSESKPEPKQESAPEPKKESAPAPSKPEPPRQAEKKDSKPQSAASSGPSMGNREERRVKMNRMRLRIAERLKQSQNTAASLTTFNEVDMSNIMEFRKLYKEDVLKKTGVKLGFMSAFSRACVLAMRDLPAVNASIEGPNGGDTIVYRDYVDISVAVATEKGLVTPVVRNVESMDMIGIEQSIADMGKKARDNKLTIEDMAGGTFTISNGGVFGSLMGTPIINLPQSAVLGLHAIKERPVAVNGKIEIRPMMYLALTYDHRLLDGREAVQFLVKVKEYIEDPRRMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0DXI0</accession>
    <name>X0DXI0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01622</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DXI0"/>
    <dbReference type="eggNOG" id="ENOG502SI6P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008719_1_3_1"/>
    <dbReference type="OrthoDB" id="4525710at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK98877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="653" mass="72276" checksum="F07841BF3D0785FD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0E3D2</accession>
    <name>X0E3D2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATPase inhibitor, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00786</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Inhibits the enzyme activity of ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ATPase inhibitor family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E3D2"/>
    <dbReference type="eggNOG" id="ENOG502SCJG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145563_0_1_1"/>
    <dbReference type="OrthoDB" id="5532350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042030">
        <property type="term" value="F:ATPase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.500">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007648">
        <property type="entry name" value="ATPase_inhibitor_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48417">
        <property type="entry name" value="ATP SYNTHASE F1 SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48417:SF1">
        <property type="entry name" value="ATP SYNTHASE F1 SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04568">
        <property type="entry name" value="IATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64602">
        <property type="entry name" value="F1 ATPase inhibitor, IF1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL00778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="96" mass="11119" checksum="0E8644084D760135" modified="2014-05-14" version="1">MLRTTFRQTAAFRPVRCFSTTPRVMTEGATGSVRPTGGSGDAFQRREKANEDYAIRQREKEKLIELKKKLQEQQQHLDRLSKHIDEITREQGGEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2A1</accession>
    <name>X0B2A1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_19036</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="JH658746">
        <property type="protein sequence ID" value="EXK76215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2A1"/>
    <dbReference type="HOGENOM" id="CLU_049768_1_3_1"/>
    <dbReference type="OrthoDB" id="4966at2759"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00642">
        <property type="entry name" value="GTP_cyclohydro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.10:FF:000003">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000012">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="13">
        <location>
            <begin position="96"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK76215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="284" mass="31270" checksum="1360E2B8B8234BBF" modified="2014-05-14" version="1">MASSKNGSVLSKKRAPNDATVSSPVSDNLTQDGRKRRKKHNLSSLGVTVDSTILSAPDQYKKSPGPVAGSGDPPTKTRTRQGDSQEQAALRLEKMQGAVRTLLECIGEDPGRDGLLDTPSRYAKALLFLTKGYHANVEDIVNNALFHEGHNEMVIVRDIDIFSLCEHHLVPFTGKESSPFPRCMHIGYIPSNTVIGLSKLPRVAEIFSRRLQIQERLTKQVAHAIMDILKPQGVAVVMESSHLCMVMRGVEKTGATTLTSCMLGCFEQKSKTRNEFMHYVGVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2G2</accession>
    <name>X0B2G2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979692">
        <property type="protein sequence ID" value="EXK75946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2G2"/>
    <dbReference type="HOGENOM" id="CLU_109015_0_0_1"/>
    <dbReference type="OrthoDB" id="10266999at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF267">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G06860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="7"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK75946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="254" mass="29147" checksum="D6611FEB386AA68C" modified="2014-05-14" version="1">MQSLPEVISNLNSDAGGLTDFTAYLSKNHCLETLQFTQDASRYRVHYAEIVEDKEIPWEYLRRHYDYLQELWDDLLGTYILPSGHREINIPSEVRARLLGLRSSVLPPHPSELDDVVKIVLELMEDSILPGFLKSYVSLDQPEDRGGDGWMRIFRRLQRKIPTPTPERAYEDSGSRTFGLREDGKATLCTRRRFLGDAPASPHSRLLRPLGEMFDHTVRGVRGMRWLKPPLENDGAADSEIDDKDEQVKAKLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5Z8</accession>
    <name>X0B5Z8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_18116</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979412">
        <property type="protein sequence ID" value="EXK77171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5Z8"/>
    <dbReference type="HOGENOM" id="CLU_036632_5_0_1"/>
    <dbReference type="OrthoDB" id="3918601at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38794">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38794:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="3">
        <location>
            <begin position="35"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK77171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="377" mass="42296" checksum="82A418139E363320" modified="2014-05-14" version="1">MSSNQRIITDNNKSPLIQVLSLMFLVIAILSCFVRTGAKLYMIKALRVDDILIIVATVLAACQTVIVFNACEHGLGQHFEVLSSSDQETFFKSQYATNTMLIASLLCCKLSGTMSLRIMAQKGQKWIIIICEAVVSAWGITALIANFFQCQPPTPWLYGDNDKCINLKAFWTYYSTANIITDIIIVIIMAENVVKIQTSWSKKILVMSVFGSRIFVTPAIVAQIHYSNKAFDSADHSFSIWPASITIQLVQCLTILTVCLPNFKPFLDSLESGQIRVDDLRRQGKTSSNGYPTNKPCYAGYKSKSGQSSRSRAPDHASKTQRSEIHEMEDFTKKPRHDHERSWDGQSRSSHSSQKILIHQTWQVEVETTHDAAARQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0B619</accession>
    <name>X0B619_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979382">
        <property type="protein sequence ID" value="EXK77595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B619"/>
    <dbReference type="eggNOG" id="ENOG502SPMR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054614_3_1_1"/>
    <dbReference type="OrthoDB" id="5343383at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="211" mass="24457" checksum="ADD01C31E2D5D331" modified="2014-05-14" version="1">MLSKSSATFFDSTCIEYVHYKSKLLDHTAFTQKDFEKHRNYHQDWEFWSSEGELMDPSDVVCIAVGHESFSRELWLNVKDCDIFEDFHAGDMLNAVPVGVFFENMKEQYKTLKLIPGRRRITIEAEKVPEHDGRITEKEVTGQTEEWGTDLDIQYARQIYRDHGWPGSFDLETASEAIDKWLEPLGGGLGGGPRGLTWQRSPSDWDETRWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6G3</accession>
    <name>X0B6G3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658617">
        <property type="protein sequence ID" value="EXK77351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6G3"/>
    <dbReference type="HOGENOM" id="CLU_1304919_0_0_1"/>
    <dbReference type="OrthoDB" id="5101988at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="211" mass="24494" checksum="8C3D7D7A5AB02735" modified="2014-05-14" version="1">MYLYLVYIRRLANSLRREQAGRSEIVQKGSDERNERLLFHVNGKAWPTSRLTEILVKATSKIWNQAINVRLYRQLAIAITERHVREVHTPFNRYDDLSSGADRNAVFAWQSGHRPLQRKTTYCLDGAYQFRLQPALLRAYEWASTRWHEFLHQPSKRWSLSDSRIPALLETSMKQRKRNIAMTSQDALALSEEANSSKLCKVASMSGSLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6K5</accession>
    <name>X0B6K5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CRAL/TRIO N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658612">
        <property type="protein sequence ID" value="EXK77396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6K5"/>
    <dbReference type="HOGENOM" id="CLU_2049798_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052432">
        <property type="entry name" value="PITP/CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL/TRIO N-terminal" evidence="1">
        <location>
            <begin position="74"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="132" mass="14986" checksum="15979BE623D46A64" modified="2014-05-14" version="1">MAIYPSALWCYREQSGLPTDASATQEQTVASEAETSKKKRFGMFRNNRAGPKLGTASSDSLAKNGVEDDKYGQTKQFHEAFANNNPETIRATMWAMVKHDHPEALVLRFLRARKRGVYVELETAKYLWMLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0B741</accession>
    <name>X0B741_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979371">
        <property type="protein sequence ID" value="EXK77955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B741"/>
    <dbReference type="HOGENOM" id="CLU_061199_0_1_1"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30897" checksum="E22370BE5E681847" modified="2014-05-14" version="1">MRKSNTESSSPRPHRPLKALCLGLPRTGTTSLAAALSVLGLRDVHQGSTMPWSDFEFFDRAADASFPNLPTYNDKGGLTREEWDALYAPCEAVIEPAGLFAQQLLDVYPGVKVIVSKRPYDVWAASFDQAILRPIFPPLVPVALLQFIQSFLSYKAWSAIYKMVLGKFGAHDYQSVKARLRDVYDEHHAMLRERVSPENLLEFDVVEGWEPLCQFLDVGVPETEFPRVNDREEMKEIRKQEVRRNTTIVLGKVTGGVLLASAAVAMWSWYFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8K6</accession>
    <name>X0B8K6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_16863</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI979360">
        <property type="protein sequence ID" value="EXK78480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8K6"/>
    <dbReference type="eggNOG" id="KOG0475">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003181_2_1_1"/>
    <dbReference type="OrthoDB" id="44789at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF3">
        <property type="entry name" value="CLC CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7 9" id="KW-0868">Chloride</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="503"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="687"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK78480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="742" mass="80661" checksum="DD88273989F75239" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8N7</accession>
    <name>X0B8N7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979366">
        <property type="protein sequence ID" value="EXK78131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8N7"/>
    <dbReference type="HOGENOM" id="CLU_918418_0_0_1"/>
    <dbReference type="OrthoDB" id="5294180at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="275" mass="30875" checksum="FAC30051AA675C43" modified="2014-05-14" version="1">MTTPTTRAPPNLEDSTEYDNKNEVLLNHLMKCVLPTISPIIESGQHCSVRTDLILAALPSNSTYLHCCLRVAAQHLKSHTNTNTSAADIDSDIKHHYCLALEALVETLKRDEDDHEATLEAVLGLILFQSAASRYDDLHDVSWHQYFGVAVSLAQELGFSYRCSFPLWNWLRSSQQSFNPDGFDRNVAWVYLIGGSISVLGSPIRAFFEDRLAQFDGSSKPNTMGRLATVLHEVWLQNDNLLDVSTPGSTTSEGGQLYIHWREVMESKGWDFLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9S0</accession>
    <name>X0B9S0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658494">
        <property type="protein sequence ID" value="EXK78900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9S0"/>
    <dbReference type="HOGENOM" id="CLU_2867706_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="64" mass="6455" checksum="22BB442626392519" modified="2014-05-14" version="1">MASAAQVSDGFQALISPRKRARPAPADQCTVGGSGSRLGETGAETGGEVAVDGGYWTVQAGQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAA5</accession>
    <name>X0BAA5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979852">
        <property type="protein sequence ID" value="EXK75743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAA5"/>
    <dbReference type="HOGENOM" id="CLU_3263224_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="42" mass="4591" checksum="6ED59672D74C56A1" modified="2014-05-14" version="1" fragment="single">LAEAQHAAERQAFKFNNDATTRPALQHKGNQSTSLESGYNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAT4</accession>
    <name>X0BAT4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979350">
        <property type="protein sequence ID" value="EXK79250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAT4"/>
    <dbReference type="eggNOG" id="ENOG502RJH8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_816458_0_0_1"/>
    <dbReference type="OrthoDB" id="5004360at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="386" mass="44866" checksum="066CFCB515D9D360" modified="2014-05-14" version="1">MEQDWEEAKHRAMRGRLHSLRIRLIDLANNLANLTTEQLGIHCGAIVEDLRSFSYDCMVEGRDRLDEAQFQWQVGEIGELMDFSVDEELKNIERDGHHKPRMTREKRRAMLMDLRIDIPFTELCFVPYDAYDFFMNLGKNLKDLVVDELRHRAQNNAMARLQSAKEEQGVSERPLPQRHLHEESITNNVLEQESRELAIRDNVYRCRWAANQIDEYQRYLQLPVTDDVASAAVEEYDDCVELQSPCPPWMSLLVLARAGDWWFAQPVNPSAKKPRSRGPMPNLEAITITRNQLRNDHEFVGDAFKKEVPEVQLSLKKLDIDFEKTIGSQFGIVVAWRFVGGDVWVGRYGHIVPKNVIDESAIHIGRSWSSTREEVRRHPFKLPSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBF5</accession>
    <name>X0BBF5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658468">
        <property type="protein sequence ID" value="EXK79500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBF5"/>
    <dbReference type="HOGENOM" id="CLU_1069746_0_0_1"/>
    <dbReference type="OrthoDB" id="1911848at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542:SF3">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="260" mass="29272" checksum="C7D3B134EB5F0192" modified="2014-05-14" version="1">MSLLRIECSTRFGIVLEYSPTIQISTLETQSRLESLYDALKNGSYRLPATEIRLRFAQNIAASVFQLLSAGWLHKSLRSDNIVLANGLQVIHSASSPEESGTVDFIIAGFEFARLDKPGQVSAGDNRPSKQDLYRHPNATSEKRARHEYQQKGYLKSYDLYSLGIVLSELGFWRRIDELQSSQAAREEWQHAPFPQYLHHRVGCDMPGMMGSRFTRVVLWCLATGQGGMGLSTDQELLAQFEEQVLIPLSQCRRAAAFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBR6</accession>
    <name>X0BBR6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658781">
        <property type="protein sequence ID" value="EXK75954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBR6"/>
    <dbReference type="HOGENOM" id="CLU_052069_1_0_1"/>
    <dbReference type="OrthoDB" id="3364649at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013218">
        <property type="entry name" value="Dsn1/Mis13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778:SF2">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08202">
        <property type="entry name" value="MIS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="230" mass="25852" checksum="95E8F67F3FA24323" modified="2014-05-14" version="1">MKQLLTWCGERALAGRPPHGTPNSNAILGARAIQDQLPKDFAARSEFSDWFNREDDGPNVPVVLRPNPRNMELDEKLAQLEINIKRLQDEKKAWQAIRKPPPEQPPLFSEGETGPIVLPDFDLLDPDEGKIRAFLADETASFDTIRSQTGSRLRTIQSSLEFQVDQLTYNIHRLEQRILVAGKEANNVLSVSALRLRQREEREKASAGTRDMPVIEVLRSLGNIRPEGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBT0</accession>
    <name>X0BBT0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979350">
        <property type="protein sequence ID" value="EXK79231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBT0"/>
    <dbReference type="HOGENOM" id="CLU_1098559_0_0_1"/>
    <dbReference type="OrthoDB" id="5428040at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="253" mass="28029" checksum="897CA47A3B952161" modified="2014-05-14" version="1">MNPLSGWSYGFRYVTLVNSGEVLNGHFESGNTTGRGTLNLEVHSGPDLWMELDGEVSIQSAYLELWVTLVEFSTLGGWSLAGNIVFNDLTTTVIWATHPEHAAMFQKILHETGNPALALQAVMFRVYQILYYDWLPIFEPTHEVTTINAQNVVVPQQWTGFIISIAILIMNFILTALTLVLFAKRTQSSLLGNAWQAVSQLVSPETQDIIRAAGSEGMKDRQVEALARSAGRNREVYALASGVDNGRIELCVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDR3</accession>
    <name>X0BDR3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WGR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658697">
        <property type="protein sequence ID" value="EXK76624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDR3"/>
    <dbReference type="HOGENOM" id="CLU_1468222_0_0_1"/>
    <dbReference type="OrthoDB" id="10504893at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008893">
        <property type="entry name" value="WGR_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05406">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="WGR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51977">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WGR" evidence="2">
        <location>
            <begin position="77"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="184" mass="20064" checksum="DD907F55D5C528F1" modified="2014-05-14" version="1">MPPRTKGPKTTKPKAAAQPTTAAKSKKTAAESKPPAKPKPPAEPKAAATAAKSKKTAAESKPPAKPKPPAEPIPPDPYHIWADPKSGVIYDAYLKKPSEFFRVQVVEDPESSKFWTRTHCGPIGELGSVRFLGNGDREKAVEMFERKFKSHSGLVWENRFVASKLGMYAYVPHYGGDSDTTDHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDZ8</accession>
    <name>X0BDZ8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">L-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="17">1.1.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Cytochrome b2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Flavocytochrome b2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">L-lactate ferricytochrome c oxidoreductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">FOQG_15082</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26 27">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>(S)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:19909"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:19910"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="22">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">In the C-terminal section; belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">In the N-terminal section; belongs to the cytochrome b5 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.3" evidence="17"/>
    <dbReference type="EMBL" id="JH658446">
        <property type="protein sequence ID" value="EXK80375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDZ8"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004460">
        <property type="term" value="F:L-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006089">
        <property type="term" value="P:lactate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02922">
        <property type="entry name" value="FCB2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000009">
        <property type="entry name" value="Cytochrome b2, mitochondrial, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000062">
        <property type="entry name" value="Cytochrome b2, mitochondrial, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037458">
        <property type="entry name" value="L-MDH/L-LDH_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF148">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE (CYTOCHROME)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="6 22" id="KW-0349">Heme</keyword>
    <keyword evidence="12 22" id="KW-0408">Iron</keyword>
    <keyword evidence="9 22" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="24">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="25">
        <location>
            <begin position="99"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00052399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00061137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00061589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00066458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00068515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00075949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00078774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00078938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="EXK80375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="459" mass="51032" checksum="ADD968BB6299CE4B" modified="2014-05-14" version="1">MVLHPAEVAQHNNANSCWLIIHNKVYDLTDFLPNHPGGKKVILKNAGKDSTADFDLVHSNDVLDKWLEPSKHLGDIDTSVAGMSANGTTQSKEPEQSKPKLSQCVNISDFESVAQQIMKKSSWNYYSTGAEDEFTIKENHAAFQRIRFRPKVLINVEHVDISTTMLGAHTSAPIYITATAHAKLGDPDGEVTLARASNKHDIIQMIPLYSSCPLYDITNAREPNRTQWYQIYVKKDRNVTRKAVEAAEARGCKALCITVDNPHLGSREKVLRSQQSESEEDEFEDAPATELDPSLIMNSTLSWDDIPWFQEITNMSIVLKGVQRVEDVIKAAEYGVQAVIISNHGGRQLDYSEAPIEVLAEAMPILRERGLQGKIEVYIDGGVRRGSDVLKALCLGARGVGIGRPFLYAMAAYGQKGLEKAIRIYKDELERNMRLLGCTSIGQLHPGLVKVLGEVRERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEJ4</accession>
    <name>X0BEJ4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658441">
        <property type="protein sequence ID" value="EXK80585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEJ4"/>
    <dbReference type="HOGENOM" id="CLU_1402502_0_0_1"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="194" mass="21377" checksum="B864D3B69F260607" modified="2014-05-14" version="1">MQRPPQPLGRGKYPPISFDFEATVMTICLNSHGQLSANLVRNDYIPPKDVNETEAELTGAPEGTRQLFAGSNVGALLCSDAQAGDKIVKVPVLGGLLVLRNISEESEYDIIGQGLLFSDHSLPLYPSRPPAGGELKEIEAYDESKYASCCKLEVEPIDYMVLERQDRGINGSRVEEKRLERLATKIYGKVKLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFH6</accession>
    <name>X0BFH6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979382">
        <property type="protein sequence ID" value="EXK77593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFH6"/>
    <dbReference type="eggNOG" id="ENOG502SYJU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1343357_0_0_1"/>
    <dbReference type="OrthoDB" id="5099182at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="24089" checksum="FBC942E539E39702" modified="2014-05-14" version="1">METSLSFSSITFIPSGFLCLEMIPLRTIALSCLALAPVAVSAGACKPRSTDLTTAASSTLETALSSEALQSTVTDLTPTIASTVETTVSSIIETTTEASTIETTSEAATTTSSAPCPSYTQIIPPPSGKVCGKEVSRGTLESSPLYLGSQLSTTGLTGCAKYCGDTPGCVSFYAEDYVPGQGAPTFKVCFMFKGYEKDIPFGEGQDGRPTYYEQGCFACVRDEAPQPPIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BG45</accession>
    <name>X0BG45_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979388">
        <property type="protein sequence ID" value="EXK77459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BG45"/>
    <dbReference type="HOGENOM" id="CLU_421528_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="650" mass="71804" checksum="03FD497287A48B6B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH94</accession>
    <name>X0BH94_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658536">
        <property type="protein sequence ID" value="EXK78198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH94"/>
    <dbReference type="HOGENOM" id="CLU_2812472_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="67" mass="7785" checksum="9504F5AAB5308EA7" modified="2014-05-14" version="1">MREQTKEQLKTIREQAAKDLDQMREQVMKELRKTHFQTADNLVSQAGHGLNDPQEQQPLVIKLGDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH97</accession>
    <name>X0BH97_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_17454</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the secreted LysM effector family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658566">
        <property type="protein sequence ID" value="EXK77844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH97"/>
    <dbReference type="HOGENOM" id="CLU_129419_0_0_1"/>
    <dbReference type="OrthoDB" id="1193027at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936311" description="LysM domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="46"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK77844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="143" mass="15832" checksum="0B6354CAE760AF0B" modified="2014-05-14" version="1">MGPSLFMKLSLLGLALINPVQSNDGCQPATWKPSVMDVGGINWRLSTLTGSQIDDNTCALILKKYHITIDTFYDLNHRLNNDCMTIQPNIRYCVEGFPEPLRAYNGLCGPDNGNATCVGTDKQYCNKNTWTCGDTLYVPEYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHA7</accession>
    <name>X0BHA7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_17441</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979374">
        <property type="protein sequence ID" value="EXK77854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHA7"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF7">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="9"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK77854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="541" mass="59275" checksum="DA2DF57D7A71D98F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHD5</accession>
    <name>X0BHD5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_17414</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658563">
        <property type="protein sequence ID" value="EXK77884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_7_1"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1361"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="201"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="3">
        <location>
            <begin position="483"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK77884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1387" mass="160007" checksum="D6D656378EE2E7A9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHE0</accession>
    <name>X0BHE0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_17059</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658532">
        <property type="protein sequence ID" value="EXK78253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHE0"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_4_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF213">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012497658" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="16"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="640" mass="70299" checksum="4AD93B7B14E366AB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHJ2</accession>
    <name>X0BHJ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979363">
        <property type="protein sequence ID" value="EXK78323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHJ2"/>
    <dbReference type="HOGENOM" id="CLU_004471_5_1_1"/>
    <dbReference type="OrthoDB" id="5078945at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="359" mass="41172" checksum="C5703698E50FFF19" modified="2014-05-14" version="1">MVYSLVQSHFRSKNLGVAEAEMQADLIRGKGKGLIVLLHGAPGVGKTSTAECVADLCQKPLYPITCGDLGITAEQVETRLKRIFVQAQKWECVLLLDEADVFLSERTNDVKHNSLVSVFLRILEYYKGILFLTTNRVGRMDEAFRSRVHVSLYYPPLDENSTLDIFKINIQRTQKRMGDKMKIDNVSIEEFAYDHFQGNHQRVRWNGRQIRNAFHIAVALAENEAINKANRKEKKKYRAPTLRAKHFDTVEQASSQFDNYLKSVLGMGQADRAKQQGRRRDDWSQEVSHNRGENDEPKTKRSTKKRRKYNISESSDDSSSEEEAPRNDGQQSSSEESESEREATIKRKKKTDKKKRNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI27</accession>
    <name>X0BI27_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979358">
        <property type="protein sequence ID" value="EXK78513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI27"/>
    <dbReference type="HOGENOM" id="CLU_031303_0_0_1"/>
    <dbReference type="OrthoDB" id="5007347at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="604" mass="67238" checksum="40AD5C9929A7A8B1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKB2</accession>
    <name>X0BKB2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979348">
        <property type="protein sequence ID" value="EXK79318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKB2"/>
    <dbReference type="HOGENOM" id="CLU_746045_0_0_1"/>
    <dbReference type="OrthoDB" id="5064767at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="455" mass="50129" checksum="4A5970CB09119042" modified="2014-05-14" version="1">MRHPTAPAKGVVFDHPMLASTYSTQPPFSTPFGPQLSYPYHPQSSGFQPFNSQASMGHYPEAPVFDYQTHSPQLFSPQLHKPQANLVGPQYYDPGSSGAYSYRSSTRANPFSSPGMFPGTENYDADLFSRLGDCTPSLRYPFPDRNVDAWLKNDVDGHEKEVPPWDPSTRQSNQATYFTPRNFGSWSYDSEAHGEQSSYTTTYQHAPYIHPSELQESYGNELQGGLPFNDSRVADQKETYGDSAGLDVPSLVVESRSYGKKINAPLQTLCRVSCNVDQYMKSPSAARAVSVWKRAHSRAHGDVNRSGNSSDVLPLREHGIKDSVDVSNEQSKEYLRCITKVTKKLNKTMSDKNDEQARQAHAAQNAQPASSQPQNLTPQQAEQERVRAELRVGYISPEVTWQRGQMNAGLPYQYTVAGGTSSQPAQQLGQPSGARTANISKFPTGQTGGTSLGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKK2</accession>
    <name>X0BKK2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Laccase-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_13247</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKK2"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_7_1_1"/>
    <dbReference type="OrthoDB" id="10255118at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13857">
        <property type="entry name" value="CuRO_1_Diphenol_Ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13886">
        <property type="entry name" value="CuRO_2_MCO_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13910">
        <property type="entry name" value="CuRO_3_MCO_like_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000071">
        <property type="entry name" value="Conidial pigment biosynthesis oxidase Abr1/brown 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF414">
        <property type="entry name" value="ADR239WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="11">
        <location>
            <begin position="142"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="264"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="519"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="75"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK82381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="682" mass="77160" checksum="D4D165E9664A7D11" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM89</accession>
    <name>X0BM89_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Alpha-galactosidase</fullName>
            <ecNumber evidence="2 5">3.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_15440</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyl hydrolase.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="2 5"/>
    <dbReference type="EMBL" id="KI979342">
        <property type="protein sequence ID" value="EXK80018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM89"/>
    <dbReference type="HOGENOM" id="CLU_009640_2_1_1"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14791">
        <property type="entry name" value="GH36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000118">
        <property type="entry name" value="Alpha-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.60">
        <property type="entry name" value="alpha-galactosidase from lactobacil brevis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038417">
        <property type="entry name" value="Alpga-gal_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050985">
        <property type="entry name" value="Alpha-glycosidase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002252">
        <property type="entry name" value="Glyco_hydro_36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031705">
        <property type="entry name" value="Glyco_hydro_36_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031704">
        <property type="entry name" value="Glyco_hydro_36_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053:SF3">
        <property type="entry name" value="ALPHA-GALACTOSIDASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053">
        <property type="entry name" value="GLYCOSIDASE FAMILY 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16874">
        <property type="entry name" value="Glyco_hydro_36C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16875">
        <property type="entry name" value="Glyco_hydro_36N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02065">
        <property type="entry name" value="Melibiase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005536">
        <property type="entry name" value="Agal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00743">
        <property type="entry name" value="GLHYDRLASE36"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 36 N-terminal" evidence="9">
        <location>
            <begin position="41"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 36 C-terminal" evidence="8">
        <location>
            <begin position="652"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="488"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="550"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="366"/>
            <end position="367"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="486"/>
            <end position="490"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="528"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="550"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005536-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005536-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK80018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="729" mass="81590" checksum="A6C6F1050C504046" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNV1</accession>
    <name>X0BNV1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658441">
        <property type="protein sequence ID" value="EXK80583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNV1"/>
    <dbReference type="HOGENOM" id="CLU_3125082_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="50" mass="5950" checksum="2DD0CD46BFC2713C" modified="2014-05-14" version="1">MQNSQKDRVRRSRELFYLVGTDPTAQRSRLRVKLHALSGRHIARMQIWVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR49</accession>
    <name>X0BR49_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11171</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR49"/>
    <dbReference type="eggNOG" id="KOG2352">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065920_2_2_1"/>
    <dbReference type="OrthoDB" id="411785at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF80">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="4">
        <location>
            <begin position="56"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="213" mass="24333" checksum="B857E12D3AA364BE" modified="2014-05-14" version="1">MTIAEDQQLGLSEYWDSRYATSNNNEPTHEWFRSFSQVLPFLQKNLLEQPGRTAQDNPRILHLGSGDSVVPAELAERGYQKQLCVDFSPVVVDMMTERHKEITGIEWSRVDVRDMPSIATGSIDVAFDKGTLDAMIYGSPWSPPDEVKENTSKYLKEVHRALKADGVFLYITFRQPHFMKLLLNPDNIFDMEMEVLGDGGGFDYYGYVIRKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRJ3</accession>
    <name>X0BRJ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bacterial alpha-L-rhamnosidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRJ3"/>
    <dbReference type="HOGENOM" id="CLU_020075_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016007">
        <property type="entry name" value="Alpha_rhamnosid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013737">
        <property type="entry name" value="Bac_rhamnosid_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307:SF6">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08531">
        <property type="entry name" value="Bac_rhamnosid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25788">
        <property type="entry name" value="Ig_Rha78A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial alpha-L-rhamnosidase N-terminal" evidence="1">
        <location>
            <begin position="84"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="217" mass="24596" checksum="92244A867681D4EE" modified="2014-05-14" version="1">MSRGAGIELRIHSFNTSQSRYLAWPGDTLESKEETCVRVRAHGLTYQPSTDWSDWVTVETGLIQPKDYSLYLRKNFDLNTKLTHIQKARLYITALGLYGAEINGERVEDHVLAPGFQSFKHLHVYDATEAVSRGRNAIGILVSQGWYAGRLFGHIEKRDFRNLYGFRIGAMCLLKVTLSYRTNVHIPSDKTWSSSFGPLSDSQIYNGEIYDSGKSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTF6</accession>
    <name>X0BTF6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTF6"/>
    <dbReference type="eggNOG" id="ENOG502SB4Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_973469_0_0_1"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="36979" checksum="2FE27766281DD4DB" modified="2014-05-14" version="1">MTRNLYVPFEIVLQILETSIPPGEPNRVIDIATPEVQQLVTWTRVCRATYEPATRFLRQHCVHLDSIPRLQKFLRCLNYSKTLKAGGHESLPKTIPLFAVSSIYLGLSLEEIQSIRASALVRDVFLELGGSVRRLIIDLPFRRIAMQHSIDAHIDQVFSRGLQALINLEEFVTLGGLPSLEFWRSELNVSQIWPKLRKVAGFSINLSDEGLWYNVARHRNIAHLVITRPYLLRVQKWNIKQSIGSELWNPEFGGDSTYARPLKIVIVNHEFSSPIIDTEGGNIHDPAGLLDVSPIEIPMHAKRVDYVCREWLIKAAKEDTLWGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUS0</accession>
    <name>X0BUS0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADPH-dependent FMN reductase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUS0"/>
    <dbReference type="eggNOG" id="KOG4530">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055322_2_0_1"/>
    <dbReference type="OrthoDB" id="68575at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050712">
        <property type="entry name" value="NAD(P)H-dep_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30543">
        <property type="entry name" value="CHROMATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30543:SF21">
        <property type="entry name" value="NAD(P)H-DEPENDENT FMN REDUCTASE LOT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADPH-dependent FMN reductase-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="212" mass="22707" checksum="BAB10B86CDEB79D9" modified="2014-05-14" version="1">MAAIKNIALITTSTRKSRVGPQVTSVINDILTGDADASKNTKISLVDVADFNLPVFDEEIMPAMVPDKGSFKHAHSIAWSNEIKKHDGYVIVIPEYNFGLAGGTKNAIDYLYNEWIGKGVLIISYGIFGGKAASESLDKTLKGMKLNVVDTRPALGFHGGVGDDLWLAGAGKLGDETKKDIIAETPTILKAFGELKDLMDKQVPKDTATNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVA9</accession>
    <name>X0BVA9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10247</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVA9"/>
    <dbReference type="eggNOG" id="ENOG502QSDU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004835_4_0_1"/>
    <dbReference type="OrthoDB" id="4685598at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000008">
        <property type="entry name" value="C6 zinc finger domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF2">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="697" mass="77487" checksum="261897A05EABFAE1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVE9</accession>
    <name>X0BVE9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12849</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVE9"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF3">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK82888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="677" mass="76056" checksum="07F8BC7B46BDE902" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZR6</accession>
    <name>X0BZR6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZR6"/>
    <dbReference type="HOGENOM" id="CLU_1372266_0_0_1"/>
    <dbReference type="OrthoDB" id="4975676at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="200" mass="22053" checksum="C19DDB2EC66124B2" modified="2014-05-14" version="1">MSDFHTRIPCREITSLSKLYNVLTTEYGNMYYKLETENNEHGELFYVVGISCHFARDVKELLVTKGVLRKSARPRGFAAINGPRPREDPLPEVIDLTWDDSDEEPPPAHGSTNTVNIPRDLTPGSRRLLAGAEETSDYIAKSVSSQRDSPEQTHSAVTRTPENHSGAEQRPIAAGNSAVGQGDRRTGRIPISMLLDGAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0G4</accession>
    <name>X0C0G4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TPR domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0G4"/>
    <dbReference type="eggNOG" id="ENOG502QU74">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011527_0_1_1"/>
    <dbReference type="OrthoDB" id="414774at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45588">
        <property type="entry name" value="TPR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45588:SF1">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="62172" checksum="DB5B2B5A0517C216" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C105</accession>
    <name>X0C105_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">URE2-nitrogen catabolite repression regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08703</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C105"/>
    <dbReference type="eggNOG" id="KOG0867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_14_0_1"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="63"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="158"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK87806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="35767" checksum="40FFB7CF592F06B4" modified="2014-05-14" version="1">MASLHRSMTMRSTIKPPYMSLSFRSTLSCRSQLSQDFNYPLRSASIIPKRSYSMARPTGLIASKGIELLSWGTPNGVKAHILLEELRDAYGLDYTIQSIDIGLNVQKEPWFTAINPNGRIPVLVDHDNNDLAVFEGNAILSYLTRKYDSENKLSFKIDDDDYTRAESWVGWQHGGIGPMEGQAFHFIGVKPEIPYAIQRYVGETERLFGVLDKRLSDRDYIVGPGKGRYSIADIALIGWTDRLPGTTISYDQFPNVKAWLARILERPAVKRGLLLPSGKDKPTGLDPVDEETMRKRAELKEVVDKAKEQFGYKYSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0C176</accession>
    <name>X0C176_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_08760</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C176"/>
    <dbReference type="eggNOG" id="KOG0761">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_0_0_1"/>
    <dbReference type="OrthoDB" id="1747031at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045315">
        <property type="entry name" value="Mtm1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760:SF2">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="69"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="232"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="355"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK87891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="471" mass="51393" checksum="A86648AA62275F75" modified="2014-05-14" version="1">MATAGTNRPSGYDHHNHHQNPLQADDEFSLRHMMDAEPTGPNDGRDVLSGSKSIPAAGAGSSNNGVVDITATQKMVSAMSGSLLTSLLVTPLDVVRVRLQSQKAPRSTVDFSKLAITTTSLSPAQTAELGITSCCREVFFSGGNAEFCLAAPRIDGIVAPPAPAECAVEEVQRRTFSSTFDGLRKIARNEGVTTLWRGLSPTLVMAVPSNIIYFTGYDYLRFNPKSPFSHFSDTSAPLTAGSAARVLAATAVSPIELVKTRMQAAHGASTTNHLVEAFESVKEMVGSHGYTALWRGLTLTLWRDVPFSGLYWWGYESIRSRLTDYREQRHGHSLPFEEDLSEARRRLQVQENHTETFVDAFTAGALSGAFASFVTTPFDVGKTRTQIYQDSSKKAKQSSASAVAAPEERSMVRLLWHIFKTEGASGLWKGWIPRTLKVAPACAIMISSYEVGKRAFRGVNERRLHSSNDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1U8</accession>
    <name>X0C1U8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_11247</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1U8"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000012">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF177">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="519"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="62"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK84724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="557" mass="59510" checksum="33753F3CA9ABBF93" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3I9</accession>
    <name>X0C3I9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658619">
        <property type="protein sequence ID" value="EXK77342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3I9"/>
    <dbReference type="HOGENOM" id="CLU_112970_1_0_1"/>
    <dbReference type="OrthoDB" id="2563633at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="150" mass="15827" checksum="7288BA7775BCB28B" modified="2014-05-14" version="1">MPSIIQHALAGEAILNGAFSIASILFPGRLLSSLVASESVPNSTSAVFKFFGAVTLGMSAPMVLSIADSRDAAAKRKLTYTSCSVIESALVSIVLWQTTQPGASGFTFNGLISLLGSVVPALVWHLYVLLSKPHWFKPESAYSAEGRKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3K8</accession>
    <name>X0C3K8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3K8"/>
    <dbReference type="eggNOG" id="ENOG502SVGP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2941790_0_0_1"/>
    <dbReference type="OrthoDB" id="4825549at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937352" evidence="1">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="60" mass="6576" checksum="C23DD40353F58551" modified="2014-05-14" version="1">MKSFISIILVIAFISLSINTVSARCFWTGAKWKDRAAARQHVVNACKGHKVGCRKKIGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3V3</accession>
    <name>X0C3V3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08101</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3V3"/>
    <dbReference type="eggNOG" id="ENOG502S12R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044876_3_2_1"/>
    <dbReference type="OrthoDB" id="9974981at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF1">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="299" mass="32163" checksum="9224D359FB6ECA09" modified="2014-05-14" version="1">MSAYKNIAVAGAAGDLGSAVFKALIDSNKFNLTVLTRAGSTSKFPSGIKVIQVDYESLDSLTSALQGQDAVVSTLGSLAIPSQSLLIDAAVAAGVKRFLPSEFGSNLVIPSVRKLPVFKTKVDIEDKLTALANEGKISYTFVYNSAFLDWGLNHGLFLDFKKAEATLWDGGNTEFSTTTLASVGQAVVGVLTHPAETKDRVVYIQDTVVSQKKLLDIAKELNPNKQWTVKEAKIDDATAASDANIAKGIFDWPTLAAYLYRAIFDPSSVPKFPKLDNELLGVKGVTDEQIKELVKPFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4A5</accession>
    <name>X0C4A5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4A5"/>
    <dbReference type="eggNOG" id="ENOG502SUW7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052707_0_0_1"/>
    <dbReference type="OrthoDB" id="3641682at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936753" description="Ig-like domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="33284" checksum="8BAA2A0A0B8B16F6" modified="2014-05-14" version="1">MRSLPIALALAATAVSADVQIVWQHAKASSQTALSVYDGSTLLAQSCSSFISDAPSSIDFTDVDENGFGNFTVGANKYLVHSKAKYSGGPICTKKFSAEATVVECSGLNWKPNKAKIEDNCHDKDEAKGALRFLSSKGSASDIAKREANPINDPPACSVLTRTSLVGDGDPHQNYFHKQLSEVVNCGTAQSCSVGNSQSISYTIGWTATLTPVSWISGGFSVSESWNTGNTYTCTGGPGEDVCVWYNTAHTAYTVQNKERDSCAVGGGWDSTGDPFVMYSPNDSNRGGGYYCVIGTCRAQGDNYWDYSGRAGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4G3</accession>
    <name>X0C4G3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Probable threonine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Threonyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_07932</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4G3"/>
    <dbReference type="SMR" id="X0C4G3"/>
    <dbReference type="eggNOG" id="KOG1637">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008554_0_1_1"/>
    <dbReference type="OrthoDB" id="5423599at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01667">
        <property type="entry name" value="TGS_ThrRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00860">
        <property type="entry name" value="ThrRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000019">
        <property type="entry name" value="Threonine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000003">
        <property type="entry name" value="Threonine--tRNA ligase 2, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000006">
        <property type="entry name" value="Threonine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000005">
        <property type="entry name" value="Threonyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047246">
        <property type="entry name" value="ThrRS_anticodon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF46">
        <property type="entry name" value="THREONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGS" evidence="15">
        <location>
            <begin position="111"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="370"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="36"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00072369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK89280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="777" mass="88369" checksum="30989C8DE20D894B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C599</accession>
    <name>X0C599_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979372">
        <property type="protein sequence ID" value="EXK77932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C599"/>
    <dbReference type="HOGENOM" id="CLU_3335604_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="38" mass="4088" checksum="547924D211AAA27A" modified="2014-05-14" version="1">MVPTSLSEMNGPQPEIRYGIIASGNTLIKDAATRDKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5P4</accession>
    <name>X0C5P4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Dihydroxyacetone kinase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_07755</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13941"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15773"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.29"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; glycerol fermentation; glycerone phosphate from glycerol (oxidative route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5P4"/>
    <dbReference type="eggNOG" id="KOG2426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017054_6_0_1"/>
    <dbReference type="OrthoDB" id="1724672at2759"/>
    <dbReference type="UniPathway" id="UPA00617">
        <property type="reaction ID" value="UER00669"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050354">
        <property type="term" value="F:triokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019588">
        <property type="term" value="P:anaerobic glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.340:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1180.20:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10440:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase, DhaK subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012734">
        <property type="entry name" value="DhaK_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02361">
        <property type="entry name" value="dak_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF4">
        <property type="entry name" value="TRIOKINASE_FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="14">
        <location>
            <begin position="10"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="13">
        <location>
            <begin position="371"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-hemiaminal-histidine intermediate" evidence="11">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="56"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR612734-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR612734-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK89690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="61555" checksum="51C41A37328AD6EC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5Q5</accession>
    <name>X0C5Q5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_10180</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5Q5"/>
    <dbReference type="eggNOG" id="ENOG502S098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006016_0_1_1"/>
    <dbReference type="OrthoDB" id="5093543at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07491">
        <property type="entry name" value="Peptidases_S8_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="888"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="217"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="686"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="269"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="346"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="353"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="692"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="730"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="887"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK86134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="987" mass="109788" checksum="AC7A830F3BDE9830" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0C781</accession>
    <name>X0C781_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA repair protein RAD51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_07444</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required both for recombination and for the repair of DNA damage caused by X-rays.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the RecA family. RAD51 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C781"/>
    <dbReference type="eggNOG" id="KOG1433">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041732_0_0_1"/>
    <dbReference type="OrthoDB" id="10251254at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990426">
        <property type="term" value="P:mitotic recombination-dependent replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19513">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000008">
        <property type="entry name" value="DNA repair protein RAD51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000092">
        <property type="entry name" value="DNA repair protein Rad51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011941">
        <property type="entry name" value="DNA_recomb/repair_Rad51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02239">
        <property type="entry name" value="recomb_RAD51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF39">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="9">
        <location>
            <begin position="99"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="10">
        <location>
            <begin position="279"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK90006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="348" mass="37534" checksum="BFDF3BF8D75384AC" modified="2014-05-14" version="1">MSEEYDEAQMGEEGGMPGPGAPTPLSALEGIAGLTKRDIQLVIDGGYNTVESVAYTPRRVLEQIKGISEQKATKILGEASKLVPMGFTTATEMHQRRSELISITTGSKNLDTLLAGGIETGSVTELFGEFRTGKSQICHTLAVTCQLPFDMGGGEGKCMYIDTEGTFRPVRLLGVANRFGLSGEEVLDNVAYARAYNSDHQLQLLNQAAAMMCETRFSLLIVDSATSLYRTDFCGRGELSNRQTHLAKFMRTLQRLADEFGIAVVITNQVVAQVDGGPSAMFNPDPKKPIGGNIIAHASTTRISLKKGRGETRIAKIYDSPCLPESDTLFAIGEEGIGDPAPKDMEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7B3</accession>
    <name>X0C7B3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_16731</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Efflux pump involved in export of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties. Constitutes a self-protecting mechanism of the fungus against critical levels of FSA within the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979354">
        <property type="protein sequence ID" value="EXK78617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7B3"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_1_3_1"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140115">
        <property type="term" value="P:export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF60">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="48"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00054466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK78617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="486" mass="53658" checksum="4A5ABD6F18B23954" modified="2014-05-14" version="1">MTADVKEPVLDTELGVLNSTPPDPYLVAFNELDSDNPKNWPEKRKWAVTNVLSITGFNRILVSTVMAPALSVIAKDLDMTATQSVMALSIYLLATAFGPLVIGPLSEVYGRKTILHVSNIWFLVWNLACGFANSKEMLIGTRFLAGFGASAVYALGGGVLGDIWRPDQRGKSLGWYSVIPLIGAATGPVIGGFMTDRISWRWMFWSTSMFQVAMAAISFTTFRETYAPAILKKRAKKLRKETGQPYYTYAERTQEGHTLRKVLTQAMTRPVRLIAFHPIIQVAAVISAIGYGLLYIVLSSFAEVWAQHYGQSVEISGLHYISCALGELAGSQLGAPLMDYWFRRTERRNGQHLPENRVPLMAMGAFIAPIGFIVYGWCAEFRVHWAWVDVAMFITMFGMQISGMPLQAYLIDAYPDHTSSAIAAQQFPRSLAAFLFPLFTPKMYAALGYGWGNSAMAFAELALELAAPLLLWKVGASLRARATSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7P7</accession>
    <name>X0C7P7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658506">
        <property type="protein sequence ID" value="EXK78727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7P7"/>
    <dbReference type="HOGENOM" id="CLU_035736_0_0_1"/>
    <dbReference type="OrthoDB" id="2247093at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="430" mass="46157" checksum="14553FD27416D4E2" modified="2014-05-14" version="1">MALCIQNILNNSPAFDGNTSSSRATRPPSLTPEPSPGASSCPQSPYTPTDLSGTALGQAVPAKRSLEDGTTEDVRPQYPNLHPLTGVHTGPPSAMSDPGRLHSQLSIASPRTQAPLSSLPLSYAPGPSQPPLVHGQTSYSPNMQAGRPFPSPRPSSETASPWSERQRGHGMAGSLFGVEGHQALLAIPGSETPIPVHVDFSQASKKADEKRQRNAVASTRHRRKKKIMQEENSKQLQELRDERRLMEIRIEELIQQRDFYREDRNRLRDIVAQTPSISGHAAGPPSPTISTTNSYAETGPLASGPSGSMGYGGDTVSNARPVKRRRTDDHPEYSLPPYESPASGHLIASPSGLPPMPMPGYGGSPRPFSVTSSANGERLPPLRAMGGRPPTGSPPGSSVQEQDPRTGQWVPVQPRVPETGWATRDTHRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7Z0</accession>
    <name>X0C7Z0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_09148</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7Z0"/>
    <dbReference type="eggNOG" id="KOG3204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076922_0_0_1"/>
    <dbReference type="OrthoDB" id="1882297at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3250:FF:000001">
        <property type="entry name" value="60S ribosomal protein L13a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_uL13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK87313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="202" mass="22720" checksum="611F2CD4A4077E27" modified="2014-05-14" version="1">MSSFEQVVVIDGKGHLLGRLASIVAKQLLSGQKIVIVRCEALNISGEFFRAKLKYHAHLRKITRYNPTRGGPFHFRAPSRIFYKAVRGMIPHKTARGAAALERLKVFEGVPPPYDKTKKVVVPQALRVLRLQPGRKFCTVGRLSSEVGWKYEDVVARLEERRKAKGAAFYERKKIAARQLADAKKNASVKEETAKALANYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9E2</accession>
    <name>X0C9E2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell division cycle 20-like protein 1, cofactor-APC complex</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_08721</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9E2"/>
    <dbReference type="eggNOG" id="KOG2620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024949_1_0_1"/>
    <dbReference type="OrthoDB" id="434619at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08829">
        <property type="entry name" value="SPFH_paraslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="STML2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF10">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="5">
        <location>
            <begin position="65"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="358"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK87828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="402" mass="43075" checksum="10F6F968CCA6DAFA" modified="2014-05-14" version="1">MAMSLTRTALRAPQSRLITAAAAITARSIAAHRSFSTTNHALLPSGFGSPVLPSYFSKPRLPANTVVRFVPQQTAWIVERMGKFNRILDPGLAILVPFIDRIAYVKSLKEVAIEIPSQSAITADNVTLELDGVLFTRVFDAYKASYGVEDAEYAISQLAQTTMRSEIGQLTLDHVLKERAALNTNITAAINDAAEAWGVTCLRYEIRDIHAPGAVVEAMHRQVTAERSKRAEILESEGQRQSAINIAEGKKQSVILASEALRAERINEADGEAEAIRLKATATAQGIDAVSESILKGDAGAQAAVSLRVAEKYVDAFGKLARESTAVVVPGNVGDISGMIATGLSVFGKVGQAQAQSMAKSLVEPKKEGSETETDTPSELDSQEKPGVKETVIESFNQAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CA67</accession>
    <name>X0CA67_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamine amidotransferase type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08509</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CA67"/>
    <dbReference type="eggNOG" id="KOG0573">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012368_2_0_1"/>
    <dbReference type="OrthoDB" id="10252281at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03766">
        <property type="entry name" value="Gn_AT_II_novel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051857">
        <property type="entry name" value="Asn_synthetase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937:SF1">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="4">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK88103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="538" mass="59320" checksum="C6FFDEB39CA1F76A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAF1</accession>
    <name>X0CAF1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidohydrolase ytcJ-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_06188</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAF1"/>
    <dbReference type="eggNOG" id="ENOG502S2A5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009942_6_1_1"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936259" evidence="2">
        <location>
            <begin position="20"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase 3" evidence="3">
        <location>
            <begin position="74"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK91405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="656" mass="71273" checksum="79150CD6FC756853" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDF3</accession>
    <name>X0CDF3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDF3"/>
    <dbReference type="HOGENOM" id="CLU_2250265_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="104" mass="11579" checksum="D1F2CD8C15D5347B" modified="2014-05-14" version="1">MLRPAQEGNSMTSDISWSCNRYSKSLPSSVVNVVTTLSCNYYTVIRAADEVGLHAHVERRTGVHCHVSVPYPKCPRASFPRGAYHCRDWPCLILVDTLKSGEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEC4</accession>
    <name>X0CEC4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14509</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK80987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEC4"/>
    <dbReference type="eggNOG" id="ENOG502TC4E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2573990_0_0_1"/>
    <dbReference type="OrthoDB" id="5048815at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="92" mass="10406" checksum="929A02548DB8A347" modified="2014-05-14" version="1">MSDQLSVEEIDDVELPGALQRLDDTQLDGTIQGLNSNQIPRVLLAIKSMNDEQGQRIIQRLDPSKDNRIQTFDTSIVFPYHCTFKSSNTINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFA5</accession>
    <name>X0CFA5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RAVE complex protein Rav1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1064">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="342131at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052208">
        <property type="entry name" value="DmX-like/RAVE_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022033">
        <property type="entry name" value="Rav1p_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950:SF9">
        <property type="entry name" value="RABCONNECTIN-3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950">
        <property type="entry name" value="RABCONNECTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12234">
        <property type="entry name" value="Rav1p_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAVE complex protein Rav1 C-terminal" evidence="2">
        <location>
            <begin position="609"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1287"/>
            <end position="1318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1318" mass="148991" checksum="32047A3EEE6E10D7" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHM2</accession>
    <name>X0CHM2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_06914</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHM2"/>
    <dbReference type="eggNOG" id="KOG4400">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023950_0_0_1"/>
    <dbReference type="OrthoDB" id="7608935at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051644">
        <property type="entry name" value="TRAMP_AT-DNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="310"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="328"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="374"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="411"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="202"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="259"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="519"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="521"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="538"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="618"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK90753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="631" mass="68508" checksum="49BA103961228B08" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHQ2</accession>
    <name>X0CHQ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_05109</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHQ2"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_9_3_1"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05474">
        <property type="entry name" value="SAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033876">
        <property type="entry name" value="SAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937195" description="Peptidase A1 domain-containing protein" evidence="10">
        <location>
            <begin position="20"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="11">
        <location>
            <begin position="56"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="423"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK93960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="494" mass="52974" checksum="E56753C12BDEE23A" modified="2014-05-14" version="1">MKSSLVGASLVSTLGLVQAQTIQWNIEGRHPQPHLARRAKTTYEEVISNDRSEGGYFTEVTIGNPPQNITLQLDTGSSDVWVPWNCADICEDDKNGKSGCPLGSFDPDKSKTFKHVAPGMFGITFVDDSYVKGDYFEDHFELDGAVINNLTMGLAIKTNISYGLIGVGYAKNEASGSTTDVIYPNLPVAMYQAGYINTIAYSVWLNDLDAKAGSILFGGVDTAKYVGDMHRIDIQKLDGHYYHFVVALTSLVATSSSGSDVLTSDSFPIQAVLDSGTTLSYLPQDLAHEIWEEVGAVWSPYYGVAVLPCAYGRNQGNFTFGFAGPDGPSISVGMDELVLSMTSDAANMPVFESGAYKGENICTFGIQNDTNDLYLLGNTFLRSAYVVYDLVNNEVGIAATDFNSTKSKRVPFKSYGATIPSATASSNQHRATEKPTVPGHNFTAAEGFQESDSNGNDDKGNAGSLLNPPTTPLALVVTTMSFMLAGGGIFSSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJL1</accession>
    <name>X0CJL1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJL1"/>
    <dbReference type="HOGENOM" id="CLU_083365_0_0_1"/>
    <dbReference type="OrthoDB" id="437457at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="240" mass="27217" checksum="BC9052294493DB9D" modified="2014-05-14" version="1">MDDMSTKDFRHLVDFFNNSDWNPTIGDIDRYSDKTTPALFVVDPFLPDGDSNPHFTVCNVIGNHNLVTEVNIAAMIDGKHRCQHVRCNELSWPINLFCPMSLKRHAFLLGPLILGLPWIGRNAIHADVHGGSARGAFTNSRGSMSYARFNHGVMLGYKGIVVDQFHHGRRDSRLRCVMQQDSPIALTCFWNDLKAGKEKIKNQHEYNQQISFADAPSPYNDKPMLFELASIMFKNLVKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM53</accession>
    <name>X0CM53_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">FOQG_04085</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="14 15">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000907_4_3_1"/>
    <dbReference type="OrthoDB" id="416741at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050688">
        <property type="term" value="P:regulation of defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18034">
        <property type="entry name" value="DEXHc_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000015">
        <property type="entry name" value="Dicer-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF62">
        <property type="entry name" value="DICER-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-0930">Antiviral protein</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="85"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="406"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="20">
        <location>
            <begin position="608"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="PAZ" evidence="17">
        <location>
            <begin position="842"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="16">
        <location>
            <begin position="1041"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="16">
        <location>
            <begin position="1200"/>
            <end position="1358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00035116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EXK95520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1406" mass="160130" checksum="D8520680DEF1C15F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNA1</accession>
    <name>X0CNA1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNA1"/>
    <dbReference type="HOGENOM" id="CLU_1768143_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="147" mass="16905" checksum="9C8496137A43F56F" modified="2014-05-14" version="1">MLRSTRQVPLEVERMVCGMLLDMIAVNSTPYRCSFWWRVSFSPYSVRTNQCIHFELDGILPTITLRHPVVGTCADSVDGLRLCACHGRWRPMTSNRLTSIVRLSYPNVGSDHQLDKKDTRFVTCVTAFLVNKVRSWFHNESSPEQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNX2</accession>
    <name>X0CNX2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNX2"/>
    <dbReference type="eggNOG" id="ENOG502S7KY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018356_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046784">
        <property type="entry name" value="Eap1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20566">
        <property type="entry name" value="Eap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="608" mass="66428" checksum="53A2E71301FD954D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPK0</accession>
    <name>X0CPK0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_05374</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPK0"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_0_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF4">
        <property type="entry name" value="ARGININE PERMEASE CAN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="62"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK93218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="561" mass="61212" checksum="CE68D8EA14D56CA4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ67</accession>
    <name>X0CQ67_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ysc84 actin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ67"/>
    <dbReference type="eggNOG" id="KOG1843">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015320_1_0_1"/>
    <dbReference type="OrthoDB" id="10255128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11524">
        <property type="entry name" value="SYLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF8">
        <property type="entry name" value="DUF500 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="1">
        <location>
            <begin position="80"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="224" mass="23574" checksum="880AF5EFCBE37B1B" modified="2014-05-14" version="1">MGLFKTADLREECEKSARILKSFVDKNKIPSNVISNAKGLAIFTGFRAGMYFAGAGGSGVVIARLPDGSWSSPSAFSVRSGSVGLVYGIDVYDCICVLNNQDAVDAYKKSEVNLGSAVALAAGPLGGNVNMGDVKPVWTYTKSRGIYGGLTVDGTVIKEKRDVNAEFYGADVPSAQILEGKVNSGWSPRIVELLEVVKKAEGKSADKSVLQGISTEPTPGDLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQG6</accession>
    <name>X0CQG6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11259</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQG6"/>
    <dbReference type="eggNOG" id="ENOG502S0U0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031975_0_0_1"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="73"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="602" mass="66313" checksum="C918A978EA859D44" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQI7</accession>
    <name>X0CQI7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">MFS transporter, SIT family, siderophore-iron:H+ symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_02111</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQI7"/>
    <dbReference type="HOGENOM" id="CLU_012970_2_1_1"/>
    <dbReference type="OrthoDB" id="4088837at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore-iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000197">
        <property type="entry name" value="Siderophore iron transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF92">
        <property type="entry name" value="GLUTATHIONE EXCHANGER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="50"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK96675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="585" mass="63799" checksum="07EE0A9622F007C0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQU0</accession>
    <name>X0CQU0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8213 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQU0"/>
    <dbReference type="eggNOG" id="ENOG502SN55">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146191_0_0_1"/>
    <dbReference type="OrthoDB" id="3660917at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058526">
        <property type="entry name" value="DUF8213"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26641">
        <property type="entry name" value="DUF8213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937848" description="DUF8213 domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8213" evidence="2">
        <location>
            <begin position="23"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="148" mass="14740" checksum="218A54CD5AA49DDA" modified="2014-05-14" version="1">MLGSLVVLVLVSLSIASPTLEKRAITCLKVGQTATASWTNSAGKKCTFTGVVGSNYGANPSGSGDYSCNGRCGAGCSGTAVGNVYTQDCFSHDICSYFNSASGGASDPNCGAAYNAAVDDTALGFANGCSQTNPSNSVAKPNSAPVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR05</accession>
    <name>X0CR05_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR05"/>
    <dbReference type="HOGENOM" id="CLU_2654579_0_0_1"/>
    <dbReference type="OrthoDB" id="5088925at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="76" mass="8507" checksum="90827D38E0A0C4D1" modified="2014-05-14" version="1">MSFHFDSALRYQSTMSTQASASKTPPEDTLFLAEIERLDVSRDGQADEAYLESLAELKHAVELISKPRGNKHVARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR73</accession>
    <name>X0CR73_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR73"/>
    <dbReference type="HOGENOM" id="CLU_2263887_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="104" mass="12523" checksum="EEBD6BEF731EC56C" modified="2014-05-14" version="1">MWIITERNRRCCYKEAIQRHKEKQVFNKFLQDSRRVPCSEAYQMRGLGRHNSHQKWGIHSTTNLHDDQLIENLAPRLARPALLFAHCCLNRPCYQVLFRIPTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRB7</accession>
    <name>X0CRB7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mannitol-1-phosphate 5-dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_02103</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19661"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:61381"/>
            <dbReference type="EC" id="1.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mannitol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.17" evidence="4"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRB7"/>
    <dbReference type="eggNOG" id="ENOG502QVPN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036089_0_1_1"/>
    <dbReference type="OrthoDB" id="418169at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008926">
        <property type="term" value="F:mannitol-1-phosphate 5-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019592">
        <property type="term" value="P:mannitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00196">
        <property type="entry name" value="Mannitol_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023028">
        <property type="entry name" value="Mannitol_1_phos_5_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000669">
        <property type="entry name" value="Mannitol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013118">
        <property type="entry name" value="Mannitol_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013131">
        <property type="entry name" value="Mannitol_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002647">
        <property type="entry name" value="PRK02318.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002652">
        <property type="entry name" value="PRK02318.2-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30524:SF0">
        <property type="entry name" value="ALTRONATE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30524">
        <property type="entry name" value="MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01232">
        <property type="entry name" value="Mannitol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08125">
        <property type="entry name" value="Mannitol_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00084">
        <property type="entry name" value="MTLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannitol dehydrogenase N-terminal" evidence="9">
        <location>
            <begin position="4"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Mannitol dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="206"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK96666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="391" mass="43630" checksum="09232EE516AD35E5" modified="2014-05-14" version="1">MGKTAVHFGAGNIGRGFVACFLHNSGYDVVFADVNDSIVNQLNNTPSYRVIEVGSEATVENTITNYKAINSRTHEEDLIETIRTAEIVTCSVGPNILKFIAPVIAKGIDRRSTEESPLHVIACENAIGATDTLAEHIKNNTDASRLEDHHLRARYANSAIDRIVPAQDPDAGLDVTLEKFFEWVVDRTPFEDVGIPDIKGINWVDNLEPFIERKLFTVNTGHATAAYHGYNRRKRTVYDALQDKDIMAEVRGALMETKNLIVSKHAIDEEAQAAYVEKIIKRIGNPHLEDAVERVGRAPLRKLSRKERFIGPAAELAENDQPIKYLLDAIEMAFRFQDVPDDEESKQLAEIMSENGPEDVVKQVCGIQDNEKIFPQLVNVVQRVQADSAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRD9</accession>
    <name>X0CRD9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Histone demethylase JARID1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_02125</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1246">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1678912at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034647">
        <property type="term" value="F:histone H3K4me/H3K4me2/H3K4me3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15518">
        <property type="entry name" value="PHD_Ecm5p_Lid2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.60:FF:000010">
        <property type="entry name" value="PHD transcription factor (Rum1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.650:FF:000014">
        <property type="entry name" value="PHD transcription factor (Rum1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000322">
        <property type="entry name" value="PHD transcription factor (Rum1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003349">
        <property type="entry name" value="JmjN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013637">
        <property type="entry name" value="Lys_sp_deMease-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004198">
        <property type="entry name" value="Znf_C5HC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF33">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02375">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08429">
        <property type="entry name" value="PLU-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02928">
        <property type="entry name" value="zf-C5HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00545">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51183">
        <property type="entry name" value="JMJN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="JmjN" evidence="12">
        <location>
            <begin position="92"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="ARID" evidence="11">
        <location>
            <begin position="157"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="456"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="13">
        <location>
            <begin position="598"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="1325"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="262"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="310"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="996"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1296"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1551"/>
            <end position="1589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1688"/>
            <end position="1724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="23"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="271"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="325"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="346"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="371"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="447"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="999"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1569"/>
            <end position="1581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK96691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1724" mass="194544" checksum="8DC9FB69FAB79F59" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTN2</accession>
    <name>X0CTN2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VanZ-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02694</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTN2"/>
    <dbReference type="eggNOG" id="ENOG502S56A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096870_0_0_1"/>
    <dbReference type="OrthoDB" id="63581at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037970">
        <property type="entry name" value="vanZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937218" description="VanZ-like domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ-like" evidence="4">
        <location>
            <begin position="34"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK97531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="204" mass="23175" checksum="DCC6C94BCC32BC19" modified="2014-05-14" version="1">MMRIRLPVAGVFLLLLLIAAYAGLTSIQLGQYVNDKVLHFTTFFALTVVFYWVVDTNRRRVMNMTLVVCTIVLGIGSEFVQSFLDNGREFDLYDIIANVIGSLLGVGLCSWYHKRMLERKRRRRYSAVPGEEQGDVELGEGHESGVMEGNSRSQTLEEEVDNWDENQIDDDWDEDEAHETSTNTQALETNADNGDLGDTKKRMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTW6</accession>
    <name>X0CTW6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_04432</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTW6"/>
    <dbReference type="HOGENOM" id="CLU_009988_1_0_1"/>
    <dbReference type="OrthoDB" id="5233646at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965">
        <property type="entry name" value="ASPARTYL PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965:SF101">
        <property type="entry name" value="HYPOTHETICAL ASPARTYL PROTEASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937221" description="Peptidase A1 domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="445"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="39"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="516"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="624"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="659"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="801"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="481"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="516"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="624"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="660"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="806"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="816"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK94309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="845" mass="92005" checksum="E43F047CA2BEDA5E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUF6</accession>
    <name>X0CUF6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_03706</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endomembrane system</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUF6"/>
    <dbReference type="eggNOG" id="KOG2034">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003488_0_0_1"/>
    <dbReference type="OrthoDB" id="1845386at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16462">
        <property type="entry name" value="RING-H2_Pep3p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007810">
        <property type="entry name" value="Pep3/Vps18_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058919">
        <property type="entry name" value="Pep3/Vps18_RING_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF26">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05131">
        <property type="entry name" value="Pep3_Vps18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26148">
        <property type="entry name" value="VPS18_RING_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pep3/Vps18 beta-propeller" evidence="10">
        <location>
            <begin position="21"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="622"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="Pep3/Vps18 RING C-terminal" evidence="11">
        <location>
            <begin position="857"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="812"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF26148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK94953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="964" mass="108895" checksum="B3B3C2028C4AF949" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVE3</accession>
    <name>X0CVE3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pre-mRNA-splicing factor CWC24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_01135</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the CWC24 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVE3"/>
    <dbReference type="eggNOG" id="KOG1813">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050460_0_0_1"/>
    <dbReference type="OrthoDB" id="25761at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034247">
        <property type="term" value="P:snoRNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16539">
        <property type="entry name" value="RING-HC_RNF113A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039971">
        <property type="entry name" value="CWC24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930:SF0">
        <property type="entry name" value="RING FINGER PROTEIN 113B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930">
        <property type="entry name" value="ZINC FINGER PROTEIN 183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="4 5 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="253"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="298"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK98126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="329" mass="36500" checksum="93CFF38D979B0477" modified="2014-05-14" version="1">MADSTTEPQASAPVFKKRGAKGKANLRKRPATPPPADSDDSDYSSSEDESGQRVKRRKKTVTVTASSKDLATGKTDLQATVYTADRNVPITSTNDATKHSNWYDEDSQDALSAKNLLGSTRTATKDSQPDGTYKGLANQTTFIQKNPDAPNRAKGPVKASSNVRTITIMDFKPDICKDYKKTGHCGFGDSCIYLHDRTDVKQGWQLDKEWEEVTRGKKNLGGTIIASANRDKKEEKAEDEAEIAMLEKIPFACIICEGPYREPIQTRCGHYFCEPCALKRYRKDPTCASCGAGTNGVFNSAKKLKKLLEKKKEREDKKKKEEEEAEEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CW88</accession>
    <name>X0CW88_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytoplasmic tRNA 2-thiolation protein 1</fullName>
            <ecNumber evidence="6">2.7.7.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cytoplasmic tRNA adenylyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NCS6</name>
        <name evidence="6" type="synonym">CTU1</name>
        <name evidence="11" type="ORF">FOQG_01539</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="6"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CW88"/>
    <dbReference type="eggNOG" id="KOG2840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026481_1_3_1"/>
    <dbReference type="OrthoDB" id="198857at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002144">
        <property type="term" value="C:cytosolic tRNA wobble base thiouridylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="CTU1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03053">
        <property type="entry name" value="CTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056369">
        <property type="entry name" value="CTU1-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032442">
        <property type="entry name" value="CTU1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000541">
        <property type="entry name" value="Ncs6/Tuc1/Ctu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035107">
        <property type="entry name" value="tRNA_thiolation_TtcA_Ctu1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807">
        <property type="entry name" value="ATPASES OF THE PP SUPERFAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807:SF12">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16503">
        <property type="entry name" value="zn-ribbon_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004976">
        <property type="entry name" value="ATPase_YdaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="9">
        <location>
            <begin position="54"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Cytoplasmic tRNA 2-thiolation protein 1 C-terminal" evidence="10">
        <location>
            <begin position="356"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR004976-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK98740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="388" mass="42751" checksum="08CC4042C27D4222" modified="2014-05-14" version="1">MAPTPCVRCQNSRAVVKRPKNHHKLCRDCFIRVFEDEVHHTITSSDLFFRGERVAIGASGGKDSTVLASVMKTLNERHNYGLDLVLLSVDEGIKGYRDDSLETVKRNAIQYDMPLEIVGYDELYGWTMDQVVETIGKKGNCTYCGVFRRQALDRGAKKLAIQHVITGHNADDVAETVLMNLLRGDMPRLSRSTSIVTGNASSEVKRSKPLKYAYEKEIVLYAHHKKLDYFSTECIYSPEAFRGTARGLIKNLEKVRPSAILDIVRSGEDMARLTPDKGQAACGCDEGEGLGGCGSANGRTSGNEMAQVEASLKKKHESTALETEITSNGTPKDDAVPLPIRTKKQKETPAPKQNLGKCVKCGYMSSQTMCQACTLLEGLNKNRAEIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXE3</accession>
    <name>X0CXE3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Small nuclear ribonucleoprotein E</fullName>
            <shortName evidence="11">snRNP-E</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Sm protein E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_09410</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXE3"/>
    <dbReference type="eggNOG" id="KOG1774">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125186_1_1_1"/>
    <dbReference type="OrthoDB" id="25620at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01718">
        <property type="entry name" value="Sm_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000031">
        <property type="entry name" value="Small nuclear ribonucleoprotein E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027078">
        <property type="entry name" value="snRNP-E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11193">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="17"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK87137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="96" mass="10959" checksum="1BE6E5DBDF56B87A" modified="2014-05-14" version="1">MTGRGGGGGRRLMLPPIKYIFELLREHATVSIWLYEQLSIRIEGKIRGFDEFMNLVIDEAVEVKQVTKTNEKETRRPLGQIMLKGDNVSLIQNVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXE4</accession>
    <name>X0CXE4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXE4"/>
    <dbReference type="HOGENOM" id="CLU_151412_0_0_1"/>
    <dbReference type="OrthoDB" id="5101068at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="96" mass="10426" checksum="D9276644BFF2FB09" modified="2014-05-14" version="1">MASPSSFITIASPTATLDALTQHYHGNPSRSDKIAIIGLTVGMAVLFLLFIVPCCCLQYLAHRQQKKEQRKEVQERATRAARLNLAAGNGSTAEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXF2</accession>
    <name>X0CXF2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXF2"/>
    <dbReference type="OrthoDB" id="1922977at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="1053"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="1053"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="324"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="390"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="440"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="628"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="753"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="879"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="223"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="547"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="566"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="599"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="640"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="753"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="788"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="893"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK99155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1155" mass="126520" checksum="C62E86BF9739CE0E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYB9</accession>
    <name>X0CYB9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03364</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYB9"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07105">
        <property type="entry name" value="ALDH_SaliADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000010">
        <property type="entry name" value="Gamma-aminobutyraldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000012">
        <property type="entry name" value="NAD-dependent succinate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF6">
        <property type="entry name" value="CYTOPLASMIC ALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="19"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK96263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="477" mass="51445" checksum="7B4DBA6FA7105959" modified="2014-05-14" version="1">MATKLHTVPFLINGSDHTSERAVDVVSPASGEVVHRYHSADVKDANAAVEAAAEAFKSWRKTRPSERRDLFLKAAEIMEKRRDELRKYSMSETGSDATWADFDISTGISHLKEVAGRIGTLEGAIPTVSDPNTTALVLREPYGVVVAIAPWNAPYILGTRSVVFPMAAGNTVVFKASEVSPRTLWAIADVFREAGLPDGVLNVIFHERANAAAVTAALIEHPEVKKINFTGSTPVGRIIGKLAGENLKPVILELGGKAPAIVWEDADLDLAALQCTLGAFMNSGQVCMSTERILVHKNVKDEFEKKLSATIEQVFSSKGDAPILIASAPVAKNKALIKDAISKGASLVHGNPDVEESSKTRMRPIVVRDVTTEMDIYKSESFGPTVSLMAIETEEEAIKIANDTEYGLSSAVFTSDLQRGLRIAREIETGAVHINNMSIHDESGLPHGGAKASGYGRFGASAGLDEWTRTKNITFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ29</accession>
    <name>X0CZ29_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_09019</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ29"/>
    <dbReference type="ESTHER" id="fusof-f9f6t8">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_3_1"/>
    <dbReference type="OrthoDB" id="6846267at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="54"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK87682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="580" mass="64782" checksum="2B05E6526145152F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZU2</accession>
    <name>X0CZU2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_02227</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit TRAPP (transport protein particle) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZU2"/>
    <dbReference type="HOGENOM" id="CLU_073154_2_1_1"/>
    <dbReference type="OrthoDB" id="10254842at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990070">
        <property type="term" value="C:TRAPPI protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000007">
        <property type="entry name" value="Trafficking protein particle complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK96813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="221" mass="24807" checksum="8511AE653F01D995" modified="2014-05-14" version="1">MSNLQPPNTVAPTPTPSGNKDPGLRYPSNGKNIYSRPLNRTKTAELSQASFAYLFGEMVTYAQRRVKGIQELEQRLNLQGHSIGLKLLDLLLFREPARTQTRPLSIIALLHFIKQNIWQHLFGRQADRLEKSANPETPDEYMIIDNEPLVNQYISVPKEMSQLNCAAYVAGIVEGVCDGADFPARVTAHTVAEGDMWPGKTVFLVKFRPEVLEREGFLGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-03-27" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0C8</accession>
    <name>X0D0C8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-dependent RNA helicase DHX8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0C8"/>
    <dbReference type="eggNOG" id="ENOG502RYIY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082565_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025633">
        <property type="entry name" value="DUF4291"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38567">
        <property type="entry name" value="DUF4291 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38567:SF1">
        <property type="entry name" value="DUF4291 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14124">
        <property type="entry name" value="DUF4291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="26699" checksum="8FF9154CD588F73B" modified="2014-05-14" version="1">MATIECLTILEQTSSTLIDFSIMPTAPSTAPYRQVRACYNDTTIIVYQAYKESIAKAAVDAQKLNASPDFKSGRMTWIKPSWAWMMYRAGYSYKDPGQSRILALRMKHEHFITLLERGVLSSHAHKLNPGEKRETTVDVRIQWDPERTAKLEVLPYRSIQIGIPGALSEQWANEWIVEIEDVTDKARVLKRVIDERPGITDEELLNMGLIFEERPFEVPEAVHTKLEMTDFPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0M4</accession>
    <name>X0D0M4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit delta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_02424</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0M4"/>
    <dbReference type="eggNOG" id="KOG1467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016218_3_1_1"/>
    <dbReference type="OrthoDB" id="10254737at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233:SF14">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK97103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="453" mass="49632" checksum="22AB011EA036B5DB" modified="2014-05-14" version="1">MSTEAEGSVPAPQTTENNDVKTEKKEQAQPQKPKEQQQAAPVGEKKLSGAELKKKAKEEKAARRAQAKASQASQGPSQGGQQASGDGKGGKAKPKQDGQHQHQQHGGAKLPIRPAAATAVVKDDKPSIPDCFSHLSMARRIEMTNADKDVHPAVLVLGEHMSAFAISDSVTRLEATLYAFQKVIDSYTTPPGFTFSRHFTPHVLNPQIEYLTACRPMCFSMGNAIRWLKLQISKVDVDLHDNDVKKLLKESIDNYIRERITLADYVIVETAANMIGHGDVVLTYAHHHLVERTLLQARKNKTDFRVILVDDPYERVGIDLAKRLSAAGIQVTYASDLGALRTHLYEATKALLAAEAIFSNGAMYARAGSCDIATAATDLNVRVVALCETVNFTERVSIDSLTYNEIDPERSTDVGFRLLFDTTRDKYISVVVTELGNSSATSVPAILRKLEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2I5</accession>
    <name>X0D2I5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Actin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08157</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the actin family. ARP1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2I5"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd10216">
        <property type="entry name" value="ASKHA_NBD_Arp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000018">
        <property type="entry name" value="Actin-like protein (Centractin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK88887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="397" mass="44473" checksum="4640256FCD20384A" modified="2014-05-14" version="1">MADSLHNAPIVLDNGSGTIRAGFAGDDLPKCYFPSWVGRPKHLRVLAGALEGEVFIGQKASTELRGLLKIRYPLEHGIVTDWDDMERIWEYVYGEGLKTLSEEHPVLLTEPPLNPRSNRDTAAQILFETFNVPALHTSIQAVLSLYASGRTTGIVLDSGDGVSHAVPVYEGFAMPSSIRRIDVAGRDVTEYMQTLLRKSGYVFHTSAEKEVVRLIKESVSYVAHDPRKEERDWVGVKPNESKFAEYVLPDGFKLKVRLFVLCSMFGQANILKIGAERFRAPEILFDPEIIGLEYPGVHQIVVDAINRTDLDLRKSLYSNIVLSGGSTLTKGFGDRLLTELQKLAVKDMRIKIFAPPERKYSTWIGGSILAGLSTFRKMWVSIDDWHENPDIIHTKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D491</accession>
    <name>X0D491_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBM-cenC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D491"/>
    <dbReference type="eggNOG" id="ENOG502RQIG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076930_0_0_1"/>
    <dbReference type="OrthoDB" id="5150344at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937442" description="CBM-cenC domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="28126" checksum="4DB2DD6469619816" modified="2014-05-14" version="1">MRWISVAAVLGAALLPASARPLCRPDRSTTTGLPSTTATTSVETLSTDSATATETSAIETTVTFVTTFTESGTATATTGFTTITSAATSEAATTTSEAPEVTNYIQNGDFEDSPNTDWSLRTSDIKNDPERARSGNKYVQYDVDDSEAVGGNQLNQTVNGLDTERLYRLTTYATVFNTPAPVKEESTICVIQALQESTIMSQWRLDFTDLGTYKPLFVDFTPVDEDVTITMRLRCTTGQKVTFSVGLDDVSLYDIGPKLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0D867</accession>
    <name>X0D867_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D867"/>
    <dbReference type="eggNOG" id="KOG3043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_5_0_1"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF80">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="2">
        <location>
            <begin position="64"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK90807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="318" mass="33823" checksum="81F840CFD2F04292" modified="2014-05-14" version="1">MADADNATRAPESDAQETPAASDNIQAPAPAAEAPVVGEHCVSDRPTPSGQSSTGEIIKLNDVDVYVSKPTDYPHAPSRLLLLLTGGTGIKSTNNQIQADKFASEGYLVLMPDLFAGDTAPGATAITDDSTSILEQFKLKAVEVTKSFLIDMWLARVTEERVMPILHKVIDAAREQYADTIKQGDGIYAAGYCVGARFVLLLAKQTKTPEGDAESGGVKNGPFIKAGALAHAASVIPDDFKDISVPLSLVCVENDPLFPDSVRIGGEDNLSDANVEHEVQVYPGVPHGFAVVGEYQDSSIKDAQATAYDQMLNWLKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9W2</accession>
    <name>X0D9W2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hsp70-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_00310</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FES1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9W2"/>
    <dbReference type="eggNOG" id="KOG2160">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084507_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000434">
        <property type="entry name" value="Hsp70 nucleotide exchange factor fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013918">
        <property type="entry name" value="Nucleotide_exch_fac_Fes1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08609">
        <property type="entry name" value="Fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Nucleotide exchange factor Fes1" evidence="8">
        <location>
            <begin position="6"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="7">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK99939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="213" mass="23698" checksum="94BDA3FD99063227" modified="2014-05-14" version="1">MDDKRLNELLKWSIEQSDATRNDPDAPAPTTQLTPELMASLMGGPSDADLMKASMDIITSDDAEQVSLDDKLIAFDNFEQLIEGLDNANNIANLSLWTPLLDQLKHDEREMRKMAAWCVGTAVQNNERTQERLLAMGGLPLLVNLATQEDEHNDVRRKAVYALSSAVRNYQPAMDLFADELTKRGHKTDKVDATSMEAVDEVVNGLREKIGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>X0DA27</accession>
    <name>X0DA27_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_00341</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DA27"/>
    <dbReference type="eggNOG" id="ENOG502SKRU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007426_3_1_1"/>
    <dbReference type="OrthoDB" id="76105at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK99999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="775" mass="86281" checksum="335A897A97CC47ED" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0DLS3</accession>
    <name>X0DLS3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DLS3"/>
    <dbReference type="eggNOG" id="ENOG502QTVK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033074_2_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="521" mass="58797" checksum="BEE0574FC75E9FB2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0DR24</accession>
    <name>X0DR24_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DR24"/>
    <dbReference type="HOGENOM" id="CLU_005931_0_0_1"/>
    <dbReference type="OrthoDB" id="9992527at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF1">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE EPSILON SUBUNIT HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="157"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="897"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="908"/>
            <end position="920"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK96707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="920" mass="104552" checksum="4596E654000E078F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0DSA7</accession>
    <name>X0DSA7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GOLD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_02446</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DSA7"/>
    <dbReference type="eggNOG" id="KOG1693">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066963_4_2_1"/>
    <dbReference type="OrthoDB" id="1929172at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938332" description="GOLD domain-containing protein" evidence="10">
        <location>
            <begin position="21"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="11">
        <location>
            <begin position="32"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK97147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="210" mass="23373" checksum="88B1D1F64EF3AAE3" modified="2014-05-14" version="1">MRLSTLVAGLFAGLVTNVAATALTYKLDANEKACFHTTTKKEGEKIAFYFAVQSGGSFDVDYVVEGPNGKIIMDGQKERQGDFVFSANVVGDYSFCFDNEMSTFAEKFVDFEIAVENESRAQLPSKQGTTPEQTSILEDSIFKVSGQLSTISRNQKYFRTRENRNFATVNSTEGRIINFSMIQIGLIICMGALQVFVVRFFFQGARKGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0DSL3</accession>
    <name>X0DSL3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA A64-2'-O-ribosylphosphate transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DSL3"/>
    <dbReference type="HOGENOM" id="CLU_027654_1_1_1"/>
    <dbReference type="OrthoDB" id="45256at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043399">
        <property type="term" value="F:tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019988">
        <property type="term" value="P:charged-tRNA amino acid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007306">
        <property type="entry name" value="Rit1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033421">
        <property type="entry name" value="Rit1_DUSP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033449">
        <property type="entry name" value="Rit1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811:SF0">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04179">
        <property type="entry name" value="Init_tRNA_PT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17184">
        <property type="entry name" value="Rit1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007747">
        <property type="entry name" value="Ribosyl_Ptfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rit1 N-terminal" evidence="2">
        <location>
            <begin position="27"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Rit1 DUSP-like" evidence="1">
        <location>
            <begin position="336"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK97237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="50189" checksum="61542EC72CFAB036" modified="2014-05-14" version="1">MPEPRFSDLILPQNEQLSMSQLMASFKRTTLTIHNRLTSIQTDANFVDLVSQAYSPRPLVANERCGSWYIPPERKGASAYFKSTDGHERAWKFSTRRLNLHLVELIENNDGIIIVDSTRRGKRMPDALSSTIPIWCTVLNLTLLPSNPSSANLYLPAHLPATTHSQICALIPGFVASFKALNLNLPTCLTKPLRPFWVTPDSSLPSVEDTSSIFDDFRPVICCTASRRVIGSEMDEGGYIQGAADDTEMWAHDLTAPLFWENIDELLKTPEAELPDLISRLVSDHAASKKDEGTQIKLTPHLSVCPLPLPANPSECRIVVTQDTTPKDNWIKSKTYMQAGLGKNKLASRNLRTSLPEICDFAAKYLASATEPNQQQIIVACESGRDLSVGVALAISCYLFDDGGNIRKSTEDVSFTKTFIKSRLGVIMTAYPGANPSRATLQSVNSFLMDWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0DUR7</accession>
    <name>X0DUR7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02978</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DUR7"/>
    <dbReference type="eggNOG" id="ENOG502SKTW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031387_1_0_1"/>
    <dbReference type="OrthoDB" id="5386330at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF17">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK97972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="453" mass="50712" checksum="6A44FA47B88448FA" modified="2014-05-14" version="1">MPSATPPKSDKVKKRPKVRGCYQCSRRRIDCDRREPTCGKCSAKGIKCSGLGLRYRFNDGIAARGKFVGKSLPVVDGLEIKSTDTTSVSNCKRRNDPFRASGYESLEQLSVEVDTTTEEEHGIQELVVSNHAPVSIDWGLDHVDPKSRFCLGYFSNNIAQLIAVINMGFNGYRDLVLPRAETDPLVRKAVLLVVEQHLSLQNGTAISLDPAAYGSLVRELIMRSHQCAPQDDDSALTALLLLHIREMISGSDNFRLIYGSLRVVVNALAKNAGEGTSDLRRFLQMQILRVCLFGESLFNETNGVHFIQAQQKACLEFITWCDRFHPELKDLLSQLASLTTWACDIYVQRAIFNPPSSETVPMIERFKQSLGQVDAYVDIVGRHLLAWPYFIVAAESSTADHREFFLDKLVKLHNTTGCWNLLRAIDQVKEIWASQSSIRWTSLLGGPTQAFIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0DZ06</accession>
    <name>X0DZ06_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rna polymerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DZ06"/>
    <dbReference type="eggNOG" id="ENOG502RPBV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_560305_0_0_1"/>
    <dbReference type="OrthoDB" id="5238996at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="386"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="452"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="45"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="54065" checksum="879056D85D8CCB83" modified="2014-05-14" version="1">MADTKVKVNGHTNGNGTAGKTLTKNTKLWQLLALAKEVSKDVGSIEDFEKSAEEREALKQELEAKQGENKRLREFNDKIVREFSDHKAQANAKTETLFAEFEQKYKTYESNKAAVEAMEREVKEAREKLAAAEVKEGEVENLKQNLAAVEAHLTSHASEIREMNAECELQKSQMEANIEELKGCKEKLTQAQSDLGEGILRDFGTEEVKKLRSDLQELSKKVHDFVNEYFNDHDGAHDSASEIQELHTRFPKIPLSTRTTKASAKMRCAAADAVIAETLLSYVFVPFYVASDMRATASSMLGFFKGDERRETVYRSQILGSLSDSEQTETVQEDIVRKASNEVRSTLHPLVVAYKQTGFYNAVPTLFRQAVALWADAQRSRDMITAEMPDEEDSRGARQYDDYDVGNARKTKGSPKPTVLAILFPQFVCRDEVIAEGVVLRSDQAAVLEALEEAKDNGGANGDAKKKPGTRRRSSAEPKSPLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0E1X8</accession>
    <name>X0E1X8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="3">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_00539</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type-1 OGG1 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="3"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E1X8"/>
    <dbReference type="eggNOG" id="KOG2875">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027543_1_1_1"/>
    <dbReference type="OrthoDB" id="238681at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1670.10:FF:000005">
        <property type="entry name" value="N-glycosylase/DNA lyase OGG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052054">
        <property type="entry name" value="Oxidative_DNA_repair_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242">
        <property type="entry name" value="8-OXOGUANINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242:SF2">
        <property type="entry name" value="N-GLYCOSYLASE_DNA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="13">
        <location>
            <begin position="131"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="370"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXL00323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="396" mass="44958" checksum="1B1C35EB834A58CE" modified="2014-05-14" version="1">MSVVGKTDWHKLPVTLGELCINTTLRCGQSFRWQKINHEWTCTLHGRLLHLKQDSTHLHYRVTFPAPKPLTPAPNNTEALLRHYFNLDTSLEPLYKQWSDADANFKKRAPQFKGVRILSQDAWETLICFICSSNNNITRISQMVYKLCQNYGPLIAYMGDEPFHDFPSPQDLTGDDVESNLRELGFGYRAKYIAETARMVANEKPETWLESLRNPDQPGFNTTPVPKEKHASYKEALAQLLTLKGVGPKVADCVCLMGLGWGEAVPVDTHVWQIAQRDYKFGKSKAKTLNKATYEAVGDHFRSLWGPFAGWAHSVLFTADLREFAAQAAKEEDEPTVIKLTAYGSTEHTRSKTRKTITITDSDTVVKEETPVIEPTDEQGLEEVKQMRRSKRVRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3P8</accession>
    <name>X0B3P8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18885</name>
        <name evidence="2" type="ORF">FOQG_18982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979554">
        <property type="protein sequence ID" value="EXK76273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979525">
        <property type="protein sequence ID" value="EXK76371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3P8"/>
    <dbReference type="HOGENOM" id="CLU_2622143_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="78" mass="8817" checksum="2F8379DC3F4735F5" modified="2014-05-14" version="1">MHTKQLRATGTGHGKMGTQLSKRKTLAMDRFLMSSLNQETLSKQTPALSRMSPMLKARWTSTTPILLLSRISTWQRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5T2</accession>
    <name>X0B5T2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658639">
        <property type="protein sequence ID" value="EXK77131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5T2"/>
    <dbReference type="HOGENOM" id="CLU_056399_1_0_1"/>
    <dbReference type="OrthoDB" id="9997739at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="12"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="305" mass="34757" checksum="2ED4CDDD1AA30E80" modified="2014-05-14" version="1">MLTDVYSVATSKPFKFIVGPQRTEFTIHSALVGHQSPALLALVNGQFKESSDCSVKWDDIDEIVFTSFWQFVYTGDYDTPEPLPPATTTSSKGKEEAHNPDEPLAETTFSNEPVEKTPTVDEVYMSTFEEESVAAAEPTSEDYIEAKPPATWYPSLVRMKKKKKVGWEVRKTTLWEDFQASWEYPSQVPEVDRALKVCANPLVHHARVYTLADRYWVTRLMQISHEKIHGSLVNLRLDEEASGDVVELVRFAFEELVPDQLRNLVVHYAACVVEHLWKDDKFQELVQNNGALSRALVGRMVLRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8Z6</accession>
    <name>X0B8Z6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658513">
        <property type="protein sequence ID" value="EXK78625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8Z6"/>
    <dbReference type="HOGENOM" id="CLU_2346747_0_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="90" mass="9876" checksum="AD16D7264D938C34" modified="2014-05-14" version="1">MKAIGTAKLFPPEEDVEVPILAQFADYLSPKVRAVTVDDEGLIVEVSADPEQDDTGFIGYLPFTATKSLHDCRTVHYSKLQELDRLGPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BA08</accession>
    <name>X0BA08_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658489">
        <property type="protein sequence ID" value="EXK78990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BA08"/>
    <dbReference type="HOGENOM" id="CLU_3050415_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="54" mass="6264" checksum="C3C49620A3456B74" modified="2014-05-14" version="1">MKTEAPESFFCEVCGKNGFSRRDNLKTHRKLHARQPNRKCRVEDAQQESEAEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-10-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAM2</accession>
    <name>X0BAM2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-L-rhamnosidase</fullName>
            <ecNumber evidence="2">3.2.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_16199</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.</text>
            <dbReference type="EC" id="3.2.1.40"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.2.1.40" evidence="2"/>
    <dbReference type="EMBL" id="JH658478">
        <property type="protein sequence ID" value="EXK79180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAM2"/>
    <dbReference type="HOGENOM" id="CLU_1045993_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030596">
        <property type="term" value="F:alpha-L-rhamnosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016007">
        <property type="entry name" value="Alpha_rhamnosid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013737">
        <property type="entry name" value="Bac_rhamnosid_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008902">
        <property type="entry name" value="Rhamnosid_concanavalin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307:SF6">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05592">
        <property type="entry name" value="Bac_rhamnosid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08531">
        <property type="entry name" value="Bac_rhamnosid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial alpha-L-rhamnosidase N-terminal" evidence="4">
        <location>
            <begin position="2"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase concanavalin-like" evidence="3">
        <location>
            <begin position="87"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="5">
        <location>
            <begin position="194"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK79180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="266" mass="29892" checksum="896E02D6496069CC" modified="2014-05-14" version="1">MILFDSSWFSKPGPALKAELYDGEKYDANLATPGWSSPQLHKDGLSVDSSWMPVTVLSPLPESVTLTAGWMEPVRPIETIDPVQLITTPSNKKVVDFGQNLVGYVRLKRDIGQKGDKVTLRHPEVLEDGELRLRPLRICEATDEYVCDGGAAASWEPSFTYHGFRYCQVDGWSMEIDLLDSIQAVVCHNDMELAGEFACSDARLNNLYRNATWSMRGNFFSIPTDCPQRDERLGWTRDIAQFAHTAVKLCDCFGFLKDWLVDPVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAY5</accession>
    <name>X0BAY5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979964">
        <property type="protein sequence ID" value="EXK75654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAY5"/>
    <dbReference type="HOGENOM" id="CLU_918430_0_0_1"/>
    <dbReference type="OrthoDB" id="3729499at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="303" mass="34141" checksum="1DCD430EA733B919" modified="2014-05-14" version="1">MDTALELLGQVDIQSLTTSERRLALTRCHAITLQLKATDALQYVRDVQSFEFQFATNALSRLKALLDKIQKDNSRDRLGIFQDFSPELVIVCGLCMTVKDIIRTQADLWDEIITQARPISERLIPYLAQSAQITAAVNSSSNNNFKKRYEALQRDQGIFNRISHIKVNDVYCFHYTAPHMPGLELLARLSYTGTVALYMPDLPRDGLLRITMRWDENFLAGLFAYQTEVHDAAGFVAYSIRAHVAQYLGAYISSAIETSDMRAAELPENIVTQCVKCQGFPGQVIMVDVTVSKAECINIMEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAY7</accession>
    <name>X0BAY7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979348">
        <property type="protein sequence ID" value="EXK79310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAY7"/>
    <dbReference type="HOGENOM" id="CLU_049915_0_0_1"/>
    <dbReference type="OrthoDB" id="10267950at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP:ADP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009163">
        <property type="entry name" value="Ap4A_phos1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043171">
        <property type="entry name" value="Ap4A_phos1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045759">
        <property type="entry name" value="Ap4A_phos1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019200">
        <property type="entry name" value="ATP_adenylylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420">
        <property type="entry name" value="AP-4-A PHOSPHORYLASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19327">
        <property type="entry name" value="Ap4A_phos_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09830">
        <property type="entry name" value="ATP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ap4A phosphorylase 1/2 N-terminal" evidence="2">
        <location>
            <begin position="32"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="ATP adenylyltransferase C-terminal" evidence="1">
        <location>
            <begin position="177"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="292" mass="32277" checksum="24BA6471498BEAEE" modified="2014-05-14" version="1">MDKSLIEAKLSSLVQAGLVFYDQEQRLIEYLDRGLKFQFLLTSALARKPTIQTAGAQTQQDIELSQQKREGSDINTAGYEICDVGRTHVLVANKFCFANPHLMLLTSDGHQRQYEPLNRGDLTAAWSILTTLGDNYVTFFNCGRDGGCSRLHKHMQLIPKPKASFASFLDADGTKEPNVPFQWFYQHFGHSKPDMDDLVTVYSDLLKQATKVGEGRSEHADSSPPGAAVPHNFLLTQRWMVVLPRRRAAVNKEAGANAIGMMGVIAVATQSEIDGWIRLGPVAALTELGVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBI9</accession>
    <name>X0BBI9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_16221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658480">
        <property type="protein sequence ID" value="EXK79146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBI9"/>
    <dbReference type="HOGENOM" id="CLU_335550_0_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF194">
        <property type="entry name" value="INVERSIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="349"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="384"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="684"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK79146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="850" mass="94021" checksum="F63886014E982520" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDX3</accession>
    <name>X0BDX3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD dependent epimerase/dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18603</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979465">
        <property type="protein sequence ID" value="EXK76659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDX3"/>
    <dbReference type="HOGENOM" id="CLU_061199_2_1_1"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF3">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="28393" checksum="659C0FC90056E95B" modified="2014-05-14" version="1">MGQHYSQPRPGTKLQVIGAGLPRTGTASISRALEILLDGPVYHGATQALLGPEREIKAWIKVLMQWRPKDNSTRRSNLDLIKEHIDGFAAITDSPCSTLVPELMTVYPDAIVICTVRDVEAWERSIAAVSSKSTQWFLRFVLFPVSSLRYFVDYIDALRQQWFLKYGETEPVTSSSYNQHITWLKENVPEDRLVFIDVHDGWEPLCKALDLPVPKDVPFQRINDRQAIDNFAKKHINRGLTNGAALIAAHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BES6</accession>
    <name>X0BES6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_15168</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins. Involved in mitophagy. Required for the switch to necrotrophic growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The mitochondrial prohibitin complex consists of two subunits (PHB1 and PHB2). The subunits assemble into a membrane-associated ring-shaped supercomplex of approximately 1 mDa. Interacts with ATG24/SNX4; the interaction is direct and plays a role in mitophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prohibitin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658448">
        <property type="protein sequence ID" value="EXK80306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BES6"/>
    <dbReference type="eggNOG" id="KOG3083">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047969_0_2_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035632">
        <property type="term" value="C:mitochondrial prohibitin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF0">
        <property type="entry name" value="PROHIBITIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="5">
        <location>
            <begin position="28"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00053189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00066275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK80306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="280" mass="30727" checksum="8349540818EC3229" modified="2014-05-14" version="1">MAAAARALNFMYRMAVPASAVVFLGSQSIYDVKGGTRAVIFDRLSGVKETVVNEGTHFLVPWLQKSIIFDVRTKPRNIATTTGSKDLQMVSLTLRVLHRPNVKALPKIYQNLGADYDERVLPSIGNEVLKAIVAQFDAAELITQREAVSERIRNDLTLRAAEFNIALEDVSITHMTFGREFTKAVEQKQIAQQDAERARFIVERAEQERQANVIRAEGESESAEAISKAIQKAGDGLIQIRKIEASREIAATLSSNPNVAYLPGGSGKQGGQYLLSVGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGD2</accession>
    <name>X0BGD2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658559">
        <property type="protein sequence ID" value="EXK77908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGD2"/>
    <dbReference type="HOGENOM" id="CLU_171236_0_0_1"/>
    <dbReference type="OrthoDB" id="3928438at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="105" mass="12074" checksum="D0B73F1C461D93BA" modified="2014-05-14" version="1">MLLYSIIVNIAILSFAPMALLVTRDAIYADDLKRYNEVMKTIVGSQILNLYSENLVIRLDIHEYPSEQIIRSEVFKPSRDADAYFRQEDELAREFLQQSSGEGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGI8</accession>
    <name>X0BGI8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NACHT-NTPase and P-loop NTPases N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979382">
        <property type="protein sequence ID" value="EXK77594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGI8"/>
    <dbReference type="HOGENOM" id="CLU_025581_1_0_1"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="655" mass="75260" checksum="4A4EA915296256FC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIF2</accession>
    <name>X0BIF2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16703</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658512">
        <property type="protein sequence ID" value="EXK78638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIF2"/>
    <dbReference type="HOGENOM" id="CLU_012997_0_0_1"/>
    <dbReference type="OrthoDB" id="5428055at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="519"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="890" mass="100703" checksum="EDA6763FE2280A92" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIL6</accession>
    <name>X0BIL6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sarcosine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_13547</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIL6"/>
    <dbReference type="eggNOG" id="KOG2820">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_2_5_1"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF7">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK82030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="310" mass="34003" checksum="22AA2D89FB03E4ED" modified="2014-05-14" version="1">MLTITGGVVFFPKLADDGASLNKFEKSMSASEFMRSLDANNIPYEVLSSQEVKKRWPSFDVAEGVQTIYTADSGIVHASKSVAAMQYQARANGAVLKEKTRVDALIPDSNGKGMTIKTSRGQFHADKVILACDAWTNKLITPLGTNIPLQIMQEQVTYYKPADVTPFDDTKFPVWIWAGNRYFYGFPSYGEPTIKAGRDTSNNFMTPEERTFVPSDDLFNELTSFMGGLIPNKGQAIRTVTCQYAITPDRQFVISPLKNHPNVIVGLGGGHAFKFAPAIGRVLAEIAIDGETKEDISNFGIPRVGADSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIP7</accession>
    <name>X0BIP7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979362">
        <property type="protein sequence ID" value="EXK78339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIP7"/>
    <dbReference type="HOGENOM" id="CLU_062847_0_0_1"/>
    <dbReference type="OrthoDB" id="5428890at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="330" mass="37265" checksum="EA129625F7093897" modified="2014-05-14" version="1">MRLFFDYYRRITADYVPDMVVGAPPALQSHTDLVSIIRLLKDNSDKKRSELTAICFSNRSPDQMPMPTDQNRALDLALRVMTMITCSLEARSADTLEAGLQPAPWAHDMTWPQFISSVFPTTEYSGLEEGAATFHQINDRVTARRLSKVARLCFVPTNELSNHLKLNQKDGTVELFHHTSFLKEVLIASQVDAKSYMSRRIAMEILDSIQKTLFPSTADATILLRSLISKHNLDADCLRFEPSAYQVAGETSSGYRYLEQRLVELYEELDNPTPRGYLEKWLERKSGARYVMMVTLAGVAIAIMLGALALAVSIFQAWVGWQQWKHPVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIV0</accession>
    <name>X0BIV0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_13486</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979330">
        <property type="protein sequence ID" value="EXK82100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIV0"/>
    <dbReference type="eggNOG" id="ENOG502SISJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025894_2_1_1"/>
    <dbReference type="OrthoDB" id="10027823at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23520">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23520:SF5">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="30"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="466"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK82100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="499" mass="54804" checksum="C11AD13DF968D16B" modified="2014-05-14" version="1">MATQRSSLGQKAGWLYHESGISAVYHAGRDAWLLILSRTCRMFAFKAVTLTIAQFFSELGFSDFRIGLFMSLTLLGDVVLGLVVTLMADGLGRRRVLVAGGFLMAVSGAIFSVFENFWILLFAAVVGVVSASGSDFGPFRAIEESMLSHITTPKTRADVLAWYITSSSLGAAGGAALAGRFVENMTKREGWNLVRAYHATFWVYILMGALNVLFAFVMSNKTEAHHDDSSEASDELAEGLLRESMEEEEDARRRRQSMTSNPHEPASRFSSVSSGTRSVMYRLWFLLTIDSLADGMVSESLTTYFLDHKFSPSKTTLGNIFSSAQVLATVSTVFAGPLARHLGLINTMVFTHLPSSISVLFFPLPSGLVVTVILLFIRMGLNNMDQAPRAAFIAAVVKPEERTAVMGITSTLRTLAMATGPSLTGGLAESGRFWIAFMVGGILRIMYDLGLWFVFVNMRLHSHETHHGESVPRGQSIDEEDVEMLRQSIESDSSQEHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJW1</accession>
    <name>X0BJW1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJW1"/>
    <dbReference type="HOGENOM" id="CLU_3351192_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="37" mass="4508" checksum="83E6EA3751390772" modified="2014-05-14" version="1">MSSKDTVRQKHIFVATCIARYFGRYLSWYTSQHRNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKR3</accession>
    <name>X0BKR3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658484">
        <property type="protein sequence ID" value="EXK79069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKR3"/>
    <dbReference type="HOGENOM" id="CLU_2996553_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="57" mass="6601" checksum="5F8BDC4358FCBBAA" modified="2014-05-14" version="1">MPGSTRSLQKRPLPCSIEIKTAVTSWTVYVKSLVRLRRISCISQALFRRHLGNRFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKS9</accession>
    <name>X0BKS9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_13174</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKS9"/>
    <dbReference type="eggNOG" id="KOG2493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015355_3_0_1"/>
    <dbReference type="OrthoDB" id="260807at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF57">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="490"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="576"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="291"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK82461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="607" mass="65277" checksum="6F6CB32E21EB5B35" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKU4</accession>
    <name>X0BKU4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658467">
        <property type="protein sequence ID" value="EXK79518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKU4"/>
    <dbReference type="eggNOG" id="ENOG502RX75">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008809_0_1_1"/>
    <dbReference type="OrthoDB" id="5340195at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF3">
        <property type="entry name" value="FORMYLMETHIONINE DEFORMYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="610"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="716" mass="80509" checksum="5DB6AF836606A229" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLB2</accession>
    <name>X0BLB2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLB2"/>
    <dbReference type="eggNOG" id="ENOG502SDNF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151411_0_0_1"/>
    <dbReference type="OrthoDB" id="3539671at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="142" mass="15083" checksum="E8FB1D72208E6ADA" modified="2014-05-14" version="1">MSSNSNDVKVALKIQHYKTVPFEPGSWNVDAKSLMAKLGAKPPAMFQKVRPTQMLMVQGVSLEISFGGDAKTAFDQDYKKTVQGGGGISVFGFRIGASGSSSEENEPHGNTWDSSSGVLTINAENSRRSANVLAVMGEIISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMJ1</accession>
    <name>X0BMJ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_12590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15245"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. Lipase family. Class 3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMJ1"/>
    <dbReference type="eggNOG" id="ENOG502RMEE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053366_0_0_1"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF24">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="4">
        <location>
            <begin position="155"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00043996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00047591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK83071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="424" mass="46820" checksum="863DA1A9B69D01B4" modified="2014-05-14" version="1">MWASKVLKGRNARSITKTSIAAAASAPTSQAEFSANSQAFSVAVTELLECLDFVLDQLDDQGEHGDLLQFHLSRLAKEISKYENSKVDEQISQPWTGDRDLLELLLAACRCACSVYKPDVHPGGDLVPVISRTPSITGTVKATSIWKSEDTNTLFVSIRGTSCKTDHLVNFNRNQKDAASVFAFPGSDERIFAHSGFLACAATLIPWLTEEIIRQVTADKSLEDIVFTGHSAGGAVAAMIFLHFVCHFPSELSNAKFSLVTFGAPPVTSTNITELAQSLPQTRHIYAVVNEHDLVPRVDQGYITSIISLYRSAYGLPLSDFNNTTFTNNTQADRNQDVIWKLPPPDFYVVGNIIVLRAKLDYNALQSTSSQTSTDTSTPPQKLDILRVSPIEFCKLLFFEISVHKRKIYLNRLERLVQESEATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMQ9</accession>
    <name>X0BMQ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMQ9"/>
    <dbReference type="HOGENOM" id="CLU_343891_0_0_1"/>
    <dbReference type="OrthoDB" id="3045089at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="948" mass="108554" checksum="1B4D5024661504D0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP99</accession>
    <name>X0BP99_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_14837</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658438">
        <property type="protein sequence ID" value="EXK80708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP99"/>
    <dbReference type="HOGENOM" id="CLU_026673_20_1_1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08297">
        <property type="entry name" value="CAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000039">
        <property type="entry name" value="Alcohol dehydrogenase AdhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF2">
        <property type="entry name" value="DEHYDROGENASE FAMILY OXIDOREDUCTASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="8">
        <location>
            <begin position="23"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK80708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="368" mass="38882" checksum="CAEBC294F0326738" modified="2014-05-14" version="1">MPSHSTNIPTVQKAAVLQGIDVGGAIELVSVPVPVLKPGQILVKMTWSGLCHSDVAIVRNYLPETPFREMALSNAQGVVGHEGVGRVVSMAEDVAAESLWRIGDRVGIKWVSSTCGKCEFCLNGKDEVLCPAQQNPGTTEPGTFQQYAATDARFATRVPEGVSDEEAAPLLCAGLTAFGATKRSQVSAGDWLVILGAGGGVGHLSLQYAKAMGMRTIAVDLGAEKGKLCQDLGADHFIDAATEPAITETVLSLTGYGAHGVVMATLDQKAYDMAPNLLRPRGTMVVVAFPKSLTFKAGASPLTMTLKMINIVGSTTGTREEMDEVLDLAARRVVLPVVNKAPLKDLDKAMDRLMEGNVLGKVVIQIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPS0</accession>
    <name>X0BPS0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15017</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658443">
        <property type="protein sequence ID" value="EXK80474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPS0"/>
    <dbReference type="HOGENOM" id="CLU_3335656_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="38" mass="4079" checksum="E36164C5265C611E" modified="2014-05-14" version="1">MAVWGGLSTQNLKAVAISLGPMEKRGEMNGRSIESVEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ80</accession>
    <name>X0BQ80_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658439">
        <property type="protein sequence ID" value="EXK80634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ80"/>
    <dbReference type="HOGENOM" id="CLU_2121228_0_0_1"/>
    <dbReference type="OrthoDB" id="4405280at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="114" mass="12230" checksum="103DBC2B0BA334DC" modified="2014-05-14" version="1">MLTGTVPGVIIETPTRPPALSCDEGGYLIQVRTLYRLNLVTGQNVQVGNNIGPRGIFNAAGFNIFDNLIYPMIQIAGVKSLVIRIGAGGSYTLISTTLNRSAFSVHQRPINVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-11-27" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQB9</accession>
    <name>X0BQB9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H/ACA ribonucleoprotein complex subunit NOP10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nucleolar protein 10</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nucleolar protein family A member 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">snoRNP protein NOP10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_11624</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NOP10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQB9"/>
    <dbReference type="HOGENOM" id="CLU_184680_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904874">
        <property type="term" value="P:positive regulation of telomerase RNA localization to Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.80.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007264">
        <property type="entry name" value="H/ACA_rnp_Nop10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036756">
        <property type="entry name" value="H/ACA_rnp_Nop10_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04135">
        <property type="entry name" value="Nop10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144210">
        <property type="entry name" value="Nop10-like SnoRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK84370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="61" mass="7244" checksum="361D299C49E61428" modified="2014-05-14" version="1">MHLMYTLDAQGNRLYTLKKVAQGQVTKSAHPARFSPDDKWSRQRVTLKRRFELLLTQQKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRC1</accession>
    <name>X0BRC1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14105</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRC1"/>
    <dbReference type="HOGENOM" id="CLU_028200_3_7_1"/>
    <dbReference type="OrthoDB" id="5429740at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936490" description="Rhodopsin domain-containing protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="9">
        <location>
            <begin position="55"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="313"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="361"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="366"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="395" mass="43583" checksum="3654CCDB31FE56B1" modified="2014-05-14" version="1">MRLFLELFFVYVCAWQTMSSPPHHTQAYLDADKGPTILGLVITVSILSTIFVAGRVYTRKRIIGALHLDDWFTIVAVIFEWCQVGVTVVAVRNGNGRHFDLLNVTQQQNVILYTILGFPFGVMAFGFPKLAVVALITRLMNPGRLHKIFLWVLAGCCMMGLIGCIIILFAQCSPVESQWTFSITDKKCWSPYVLVNFAIFAGALSAFTDLYLAVYPAVVLFHLQMNKRKKIALSFALGIGSIATIVAIYKCTRLPSLASKDFSYETSDLVIWTVIEASTIIIACCIPVLQPLVDALLGRRAFGSSPGYKNYNSSGYQNYGNSRTGQPRSNIELSDSRKLRSDDRGNMTNVKYLGSGAAELDSQESILRHDGTKTTDAHSADAHSVNAPTEGEVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTY6</accession>
    <name>X0BTY6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_13609</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK81959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTY6"/>
    <dbReference type="HOGENOM" id="CLU_1261606_0_0_1"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051140">
        <property type="entry name" value="GATA_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658:SF18">
        <property type="entry name" value="PROTEIN GAT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="6">
        <location>
            <begin position="166"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK81959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="220" mass="24569" checksum="476681F207FAE97E" modified="2014-05-14" version="1">MCYSLTSSYLIPCPASPGQPVQLKARSQRRRCQQQRPSRTEVGSSSRSPVTRSKHKQAHLQHGVQSSECVGHPLGDVNVFQTSAIASTLSNETESSHSTCHADAPCHLHDGQETLHRSQHTSTQQGTISKCQDLGVSHKRGRRKSYQSRQCHQHRQDMWRWQGNTLPAKMSCTSCHTNTTPQWREGPSGPRTLCNFCGLIYAKRQQKHHTGASSHCFSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUS4</accession>
    <name>X0BUS4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUS4"/>
    <dbReference type="eggNOG" id="ENOG502S9GH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_4_1"/>
    <dbReference type="OrthoDB" id="2498029at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF31">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN YCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="33"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="277" mass="30446" checksum="E055099A76914852" modified="2014-05-14" version="1">MSLVSTTKRIQLQDDVHLHVEQSFPQVQSQDYPTIVFLHFWGGSSRTWSPVNHLIAHIFPTARIDFRGWGSSTGPADETEYSILRLAQDVENVITRLNIQKYIIVGHSMGAKVAQAIAGRNLVNGLAGLVLLCPAPPTPLMLPKEMRDQQISAYDNAQNAEFVVRNVLTAKSLPDGIIERIVEDMIKGSPSATAAWPRYAMNENILELAKKISVPTVIIAGGKDQVEPVTRIKAEVSGNIPLAKFLVLEEVGHLALLEAPEKVAEIISDFVLSKSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV30</accession>
    <name>X0BV30_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ATP-binding cassette, subfamily B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_13232</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV30"/>
    <dbReference type="HOGENOM" id="CLU_000604_6_5_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000041">
        <property type="term" value="P:transition metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18583">
        <property type="entry name" value="ABC_6TM_HMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03253">
        <property type="entry name" value="ABCC_ATM1_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000186">
        <property type="entry name" value="ATP-binding cassette sub-family B member 7, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF651">
        <property type="entry name" value="HEAVY METAL TOLERANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="266"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="582"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="820"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="820"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK82364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="842" mass="93289" checksum="32BE39561EF661A5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWB0</accession>
    <name>X0BWB0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWB0"/>
    <dbReference type="eggNOG" id="ENOG502QRF9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029538_5_2_1"/>
    <dbReference type="OrthoDB" id="2373480at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853:SF5">
        <property type="entry name" value="LIP-DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03583">
        <property type="entry name" value="LIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029171">
        <property type="entry name" value="Esterase_LipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR029171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="46447" checksum="8E8B109FD9D67EB5" modified="2014-05-14" version="1">MASLEWLLDLRAVAKASSSGIITDDAPLENQLPPSKDPWYSAPDDWEIRQPGDVLRIRSASNLTNVVEGSAAVYHILYRSTDSRGQASWAVTTLFVPTSFYLSPSGKVAILSYQFAYNTCNVDSSPSFALSGVMAKSEPNLGIKSSTSLITEMLSFGWIINTPDHLGPTAAFGASVQAGHASLDALRAVHRLLNLRKHPGFNTAIWGYSGGSIATFAAAELQPSYSPDLSISAAVVGGLVDDISAALDKINKSPIAGTLIALLIGITAQYPEARAYLESCLVPEMKDEFMAAVNTEVTQNVGKYAGKDIYAFFKGGSAELRAPILQELYDKQAKLGYRNTPTMPMFLYKAIQDQFCTIDLTDATVDRLCEKGADIKFERNTVGNHVSEIENGKPRAFGFLRSIFDESYKSPASKRNVVDVTVDVSSQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX12</accession>
    <name>X0BX12_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658407">
        <property type="protein sequence ID" value="EXK83049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX12"/>
    <dbReference type="HOGENOM" id="CLU_2794031_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="68" mass="7778" checksum="BAA6CADDE9A4DCD7" modified="2014-05-14" version="1">MNRQRYSDILNELDKLLPYKLITNNIGRPVSLIQREQLSRNFSGFLTAINCIRQVAIVRNDSSAPSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BY29</accession>
    <name>X0BY29_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BY29"/>
    <dbReference type="HOGENOM" id="CLU_018686_0_0_1"/>
    <dbReference type="OrthoDB" id="5153959at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="434" mass="45734" checksum="FC17EF52BF713040" modified="2014-05-14" version="1">MASANFDSEQRKLCQSLTPPASQPDTASLHYKEALSTLGKSSDTAICIPSDVESDTEDEDEDSRELNSLQSYATRASTLDYLDLTGTEYGATKPEAITGVVTAPTVSLAQAEATPACRSETPVSHLADAEPSQKSCEMNHILTGDASASQDINFATPPTSPESQLYSVAADGQEPRPVPSHPDSPSTCTHSPQTTSPVEVTQASLEASEAPAGSSHDDAISEAHTPSPARSSAEPHQTQGLGDASCTPSDAASGVAEARFESPSEAQVSSPSPSPRRSRRISMQIHKTMQSKDGDGGSEGSESEDGLDGLESYYRDENSPSLADSGDSDSEDNDADGSHQGRKRRKVLKSVSCSVRSTGDSSRGSRNSRQRRSTAHAAQLPSAIRTSGRDIDTPTPSQVIPALSGANMFLARFEEWPLGDVLLKCITEGGKMTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYC7</accession>
    <name>X0BYC7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYC7"/>
    <dbReference type="eggNOG" id="ENOG502SUA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102253_0_0_1"/>
    <dbReference type="OrthoDB" id="5356630at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936810" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="19993" checksum="AA382E53A45734D1" modified="2014-05-14" version="1">MLAQTIFSILAIATTGLAAPVEPRSNDYFTPSEIHTYNINNGAIYDTDEGRVTKAPTNGGNDITTLLTFKYPEAARGKQCQFAFYLAPGENVIGSKKLDLYSSLAPAPGPRAGWGPGNQRNVHLGRMDVKVGGFATWEATYGPYMTQKTDCKKPGTVEGLELVGVYDLDAIYWNPAKSGPRIVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZA9</accession>
    <name>X0BZA9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_12011</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZA9"/>
    <dbReference type="eggNOG" id="KOG4750">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_3_0_1"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03357">
        <property type="entry name" value="LbH_MAT_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000025">
        <property type="entry name" value="Hexapeptide-repeat containing-acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051159">
        <property type="entry name" value="Hexapeptide_acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416:SF23">
        <property type="entry name" value="ACETYLTRANSFERASE C18B11.09C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416">
        <property type="entry name" value="SIALIC ACID SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Maltose/galactoside acetyltransferase" evidence="4">
        <location>
            <begin position="26"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK83854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="232" mass="25606" checksum="A004970B7DEECB72" modified="2014-05-14" version="1">MAKQQKDNEIIEFAKGLKGTPWCEEYEKMISGMLYNPLHPKLLDGRHRARGLAYKYNNIDPSAGTREEIDDKRAEMLSEMLGKVGKGTYIETPFMPDYGSNVSMGENCFMNFGLTILDTSLVIIGDRVQMGPNVHIYTAGHETSVLSRIKFVEFGHPIRIEDDCWIGGNVVILPGVTIGRGCTVGAGAVVTKSLPPYSIALGAPAKVVKTIQSVEEELADPNNPYRNMPDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZU9</accession>
    <name>X0BZU9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09214</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZU9"/>
    <dbReference type="eggNOG" id="ENOG502RZPZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013481_0_0_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF50">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="299"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="622" mass="69061" checksum="9B42508191F09D18" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0T6</accession>
    <name>X0C0T6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0T6"/>
    <dbReference type="eggNOG" id="ENOG502T5Q1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_446907_0_0_1"/>
    <dbReference type="OrthoDB" id="5426982at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="618" mass="70797" checksum="6389FC7578CD92DA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0U7</accession>
    <name>X0C0U7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658720">
        <property type="protein sequence ID" value="EXK76427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0U7"/>
    <dbReference type="HOGENOM" id="CLU_565041_0_0_1"/>
    <dbReference type="OrthoDB" id="3522001at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022698">
        <property type="entry name" value="OrsD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12013">
        <property type="entry name" value="OrsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="45459" checksum="AA8E1047EFE1866E" modified="2014-05-14" version="1">MEDIIYLNPDYQILICRLCQAAVRPGAGIESHFRFVHQLKGQVLKDIKDYFSALELADPKLIAVPKDNSLAVKQLAVSDGYSCNACRYLTIARDNIVRHWREAGHGAAEERWTQVRLQTWIGARNHTRYWIVRDDSDIDGPADTANAADARSQSAMDELIAASQARLKEEDAARLRKGDLKEDIDRDSPWVKRLGWVRHFGSRDLISIHDAAQWLRARAVTGRWAQNQEDEEAARERLLLSRLGQSFDREVDRCCWRLDSVPTETLQWLGSITSMTPSGVPFGRKGKEESMSQYKSVGHRYLSFCWKAYRIGRKEAFQCWAVRFTDEQWSLLHDVAEELESDRVPSSHDSGFFSGRERQVKDKDEDGDGDEYQDDDDSDEGEQGDEAGFLSIRVWIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0X3</accession>
    <name>X0C0X3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mucin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0X3"/>
    <dbReference type="eggNOG" id="ENOG502SPPE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008913_0_1_1"/>
    <dbReference type="OrthoDB" id="5380370at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="774" mass="86813" checksum="AE5921AB6A4FBC04" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C195</accession>
    <name>X0C195_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C195"/>
    <dbReference type="eggNOG" id="ENOG502RPUI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1660918_0_0_1"/>
    <dbReference type="OrthoDB" id="5092743at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937317" evidence="1">
        <location>
            <begin position="20"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="157" mass="15893" checksum="83E317BD479505F3" modified="2014-05-14" version="1">MLFTQVALLAAATLVAGNAAPQPEITQPAVLPRDIIPDDVKSWAEGKASAAGQDVDDWVKSHYSEAEQWASDKGADAKTWVEGQASEARDKGSEIASRASTAFDGVSSRVRTAIDEASASASAAVNNDNAAATVGGGQAGVVALMAAVGAAVFAFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1D8</accession>
    <name>X0C1D8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alpha-1,3-mannosyltransferase MNT3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_10953</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MNN1/MNT family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1D8"/>
    <dbReference type="eggNOG" id="ENOG502RZ48">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030430_1_0_1"/>
    <dbReference type="OrthoDB" id="430354at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000033">
        <property type="term" value="F:alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392:SF1">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK85003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="57723" checksum="98D770FBC9B99863" modified="2014-05-14" version="1">MLTMPSLRLSAKSIQITAAIASIWLFVGVLYHYRDVSFYTPNNNFQSTSKPSSNSRSVESIKLGARYFLDYPLKDEPKAIFGELGQRTELLQSWIEDLEGRDDSHETAELVGQILEKQFPWLNSKQVVSPPLVDIYNRLGLSYNSKSVKSDKAPAGIVIPTGEKTLRFACHLVAALTRVHKTTLPIQVVYAGDDDLSAAGRKKIQQAADGVKIEMLDVLTVFDDNTLKLADGGWAIKPFAALASRFEQVILLDADAVFFQDPRHLLLQNRFKETGVLLFHDRLLWKNGFADRQDWWHDQIKHPGPETEKSLVWTERYSEEGDSGIVVVDKSRLDVLLGLLHIGWQNSERVRNEVTYKITYGDKESWWIGFEATGSRYAFSPHYGGIVGWLGPTKAELDAAKKAEEEKKQEDNKRDDREEVRVCSFVIAHVDQNEKLLWYNGGLLKNKAVNQTEFEVPTHWMIDQKWHKGGSKQAMSCMVGTKASALTSGEKDVLAKSIQVAKDMDEKLHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1X4</accession>
    <name>X0C1X4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1X4"/>
    <dbReference type="eggNOG" id="KOG2142">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010913_2_1_1"/>
    <dbReference type="OrthoDB" id="10264306at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008265">
        <property type="term" value="F:molybdenum cofactor sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043545">
        <property type="term" value="P:molybdopterin cofactor metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF80">
        <property type="entry name" value="MOLYBDENUM COFACTOR SULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="48"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="540" mass="60338" checksum="9767684A37DD024A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1X8</accession>
    <name>X0C1X8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_18473</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979445">
        <property type="protein sequence ID" value="EXK76792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1X8"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_3_1"/>
    <dbReference type="OrthoDB" id="6339427at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF26">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="17"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK76792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="524" mass="57476" checksum="38E81B91DA740D08" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0C246</accession>
    <name>X0C246_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11089</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C246"/>
    <dbReference type="SMR" id="X0C246"/>
    <dbReference type="eggNOG" id="KOG3017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035730_5_2_1"/>
    <dbReference type="OrthoDB" id="43654at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05382">
        <property type="entry name" value="CAP_GAPR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.33.10:FF:000010">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034113">
        <property type="entry name" value="SCP_GAPR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936899" description="SCP domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="124"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="259" mass="27615" checksum="1BAB874C8F9A2BCF" modified="2014-05-14" version="1">MHFSSFIVSMMAAGAMAAPHGSWGNSNKHYKVVTEYEYVTHYVTAGGNAPQATYVPEQPAAAPVQEQQPAPVVVKKPKKNPAPQPTYVAAPEPEKEEPATTQEEAPAATQPSSDSGSGSSNLDADQQKALDLHNEARKAVGNEPLSWDDSLASGAQEWADHLAQLGSLEHSQGEDGENLYMGSGSNPYSAAVEAFLSEKSQYNGEAISGSNYMSFGHYTQCVWKTTTKVGMAVAKDSSGASWVVARYQKPGNMIGDKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C386</accession>
    <name>X0C386_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C386"/>
    <dbReference type="eggNOG" id="ENOG502S8NQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_6_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07262">
        <property type="entry name" value="VOC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35006">
        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35006:SF2">
        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="137" mass="15045" checksum="DA02B7C13EBCB734" modified="2014-05-14" version="1">MPFSHVALSVGEHYVEMRDFYKAVLAPLGYELKFEGTGNKGAQYCSFGVKNGAPDFWLGGGGPDLKKYDGNLENRTAPVHVAFDGENQKHVDEWYDTAIKAGAADNGKPGLREYRPGYYAAFVLDPVGNNIEVLHMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3T0</accession>
    <name>X0C3T0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">6-phosphogluconolactonase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3T0"/>
    <dbReference type="eggNOG" id="ENOG502S3WY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038716_0_0_1"/>
    <dbReference type="OrthoDB" id="9972196at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="48335" checksum="F7E0C6318F2BD566" modified="2014-05-14" version="1">MKFFGRQKPSKNPFRDNSTTLLVSTLLLAAPITVFLLHCVYQTYYRRGAHWSHNHDILELSTHHEPDVLLYIASYSGLVTTLNLSVAEYRDTPVKLETLSTTDGCAGSSSWLTLDWYNGVLYCTDEGLKDGKHGSLSSFATHENGTLTPLAKTSTVLGPVSAVMYGEWDYGLAVAHYGGSAFTTWDIQDPANLTSLNVQQFSISEPGPDPSRQEASHPHAAVVDPSKRFVLVPDLGADLIHIYGVGFGDLGLSKLDPLVVAPGSGPRHIAFVVKETKTFMYLVTELANTIIGYEVVYGGEFIRFKEMWNSGIHGEGKDVPQGAAAAEIVISPDREFLIISSRNESTLQVPDFDTSNGTIPSDPLVSFKIDSETGHLTLQQDIPCGGRFPRHFSINKAGTLVAVALQSDSRVVIIERDAKTGIMGDFIAYAELEGEVTAVIFYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4L3</accession>
    <name>X0C4L3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_07969</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4L3"/>
    <dbReference type="eggNOG" id="KOG3298">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085878_2_0_1"/>
    <dbReference type="OrthoDB" id="1162399at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060213">
        <property type="term" value="P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04329">
        <property type="entry name" value="RNAP_II_Rpb7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04462">
        <property type="entry name" value="S1_RNAPII_Rpb7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000043">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF4">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="8">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="78"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK89345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="172" mass="19121" checksum="C3E69FCC6B72E073" modified="2014-05-14" version="1">MFFLYNLERKVTLHPSFMGRNMHDLVTAKLLKDVEGTCAGSYFIISIMDAFEISEGRILPGLGMAEFTVGYRAVVWRPFKGETVDAVVHSINPQGFFAHAGPLQLFVSAHLIPSDVKYDPNATPPQFTNNEDTSIEPQTHVRVKIIGTRTEVGEMWAIGSIKEDYLGCLQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4U6</accession>
    <name>X0C4U6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_17525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658573">
        <property type="protein sequence ID" value="EXK77782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4U6"/>
    <dbReference type="HOGENOM" id="CLU_000288_6_16_1"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NACHT" evidence="4">
        <location>
            <begin position="402"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="950"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="992"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1034"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1076"/>
            <end position="1117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK77782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1125" mass="124352" checksum="8966CC9F331BDC00" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5S7</accession>
    <name>X0C5S7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chorismate synthase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5S7"/>
    <dbReference type="eggNOG" id="KOG4253">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044758_1_0_1"/>
    <dbReference type="OrthoDB" id="4218123at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39470:SF1">
        <property type="entry name" value="CHORISMATE SYNTHASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39470">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="39993" checksum="256766673D60576A" modified="2014-05-14" version="1">MAIPWDSLRSLLIFFGPILLPKAISYYRSVKASSQARHAPIVPVPPKVRVALALLAFLIISYILKTLPPFAPENVFLATQSRLQIPVDVLFNRVAVGRPDNVLTKQDEALRGRFVNLESRLLYLQFGPEVLANCPFCTSEEPKTFFYYALPQLLWPHIANLFAIAFVTSPTFTGRAGSQWRPKATMAAMTIAALDIYFVNSYNYQANARALRLSEVDFFYWTARVARLVTLAAFDAALGWLLYLSATNRAFVEPPSPVERIEATSRALLIVKSKLSALGIVKNTALRDEDLRSRSHAYWSHEVRLMGEVMEEREVVEGVNDALTNRIDVATITRDAEGYAQNVLHSLRGETADDDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C646</accession>
    <name>X0C646_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658537">
        <property type="protein sequence ID" value="EXK78187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C646"/>
    <dbReference type="HOGENOM" id="CLU_033551_1_0_1"/>
    <dbReference type="OrthoDB" id="5552418at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="286" mass="31212" checksum="EC6640D3C68AF087" modified="2014-05-14" version="1">MPETAIVNGSEYGHDFRQTQGFGGYSTAATMMYNVGQPSTQNTVYDAQQFSSRQPAAMQMMPQDVASSYFGSETGASAGPSLQQPTQGSSGSANVYQQSNAMSYASNSMSSVSTMPQATNTADVSLTDDHDYAEGALEEKWVSYQRQLGSIFQKIVNGSLKSASETLLSVTSWLLSQVADLGLNLDETNLHADRIQLWNDFNHAWLGLGQRQIVLMTSPQQLSSTQSLVSKAMIKKMGNELIRLCDGIERHGLVDYQYGVWEDQITAGEQILLHSESLARSANLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6W1</accession>
    <name>X0C6W1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979360">
        <property type="protein sequence ID" value="EXK78467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6W1"/>
    <dbReference type="HOGENOM" id="CLU_092115_0_0_1"/>
    <dbReference type="OrthoDB" id="1911848at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="25346" checksum="3F4A1190F6EB51AD" modified="2014-05-14" version="1">MAELALGIVGIAGTVDVCIKFGRVLVQAYKDYGQADAVVGELSVHIQICWSRLVSQLEIVKELESGMARDQRELQSQTLCILQSKLEAATLAISKPEKYASSKRIKAIQFLESTVAELESWQKRFEPTWFQMVKSGPPDLDRALKKASQTEVQNRAEPVREGLKLRQAFNTSGSVKLAEKVLQELEWKTIPYCKSELAIRKVKYFVVENVSRETVGWRDARELAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0C759</accession>
    <name>X0C759_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07435</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C759"/>
    <dbReference type="HOGENOM" id="CLU_025204_0_0_1"/>
    <dbReference type="OrthoDB" id="4491390at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF13">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="509"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK89981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="539" mass="60457" checksum="AFCAC15533B7CD74" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7Q3</accession>
    <name>X0C7Q3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658505">
        <property type="protein sequence ID" value="EXK78737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7Q3"/>
    <dbReference type="eggNOG" id="ENOG502SW3I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000692_0_1_1"/>
    <dbReference type="OrthoDB" id="4987003at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1186" mass="138010" checksum="04C00E6178C449BA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7R7</accession>
    <name>X0C7R7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09624</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7R7"/>
    <dbReference type="eggNOG" id="KOG0834">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022000_7_1_1"/>
    <dbReference type="OrthoDB" id="25002at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20546">
        <property type="entry name" value="CYCLIN_SpCG1C_ScCTK2-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000072">
        <property type="entry name" value="Cyclin Pch1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="114"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="346"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK86874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="443" mass="50295" checksum="5164271F4710DC81" modified="2014-05-14" version="1">MASIDRYRPPREGYQPPTLPANPRPERDSRSRSPRRRDAVPPAVPTPPQHSTRTSPPRPQARQPQESPARSGAQTPVASLNQWNFTSDEVRSTPSIVEGLSPAEERMRRAKGVNFIYQAGVMLDLPQITLWVAGVFFHRFFMRCHMVQEKGGIHHYNIAATALFLANKTEENCRKTKDIIIAVAKVAQKNAKLIIDEQSKEYWRWRDSILTYEEVMLEQLTFDLMVDNPYHHLFKLLDQLGIVHNKNLRQAAWAFCNDACLTSIPLLIGPRDVAISAIFFASIYANQQIEDINGEPWWKLLKGDEVLCSQAIEVMRQFYTENPLRKQNPSLPSPAFHLENTRKRGDTLLSQPDTLSSTTGTPFEVDRASRSPGVSSRVNGAAQDGEGRYPERDEGSQPRHDENGRPPRSPLKRREPDDGEEQSDRAEKRAKLSEDEEGELVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8K6</accession>
    <name>X0C8K6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8K6"/>
    <dbReference type="HOGENOM" id="CLU_2038176_0_0_1"/>
    <dbReference type="OrthoDB" id="10313497at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939205" description="Secreted protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="14209" checksum="0B15F2DC6C59BC77" modified="2014-05-14" version="1">MMTRYRCRSALCMLISLHLHMDVFPAKEWTFSATRLKTCWLRSSNTCLSVQTGPHEVMPCKSMQVSISKRMRRFLERSSAPERQDLFLPFVNQHQCQFGVLRQIQRHGPGALLYRRPTHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8Y4</accession>
    <name>X0C8Y4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Mitochondrial substrate carrier family protein L</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_06998</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8Y4"/>
    <dbReference type="eggNOG" id="KOG0762">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_16_4_1"/>
    <dbReference type="OrthoDB" id="193856at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF57">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="33"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="148"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="245"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK90885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="37208" checksum="A2BDEB3CEBE79D92" modified="2014-05-14" version="1">MAADVQGKNMLSETEPIKTQEKKTSNVSGGSGAHDYKGFVAGVFSGIAKLSVGHPFDTIKVRLQTTDPSRFSGPLQCVTQTIRNEGFRGLYKGATPPLVGWMFMDSVMLGSLTVYRRLLSEHVFNVEPLGTDVTASSPGTAPKGHTALPSFGHGIAGILAGSTVSFIAAPVEHVKARLQIQYAAQKADRLYAGPIDCLRKIYRYHGIKGIYHGLSATLLFRGFFFCWWGSYDILSRQLREKTNLSAPAVNFWAGGLSAQVFWLTSYPSDVVKQRIMTDPLGGGLNDGVRRFPRWKDAAVAVYREGGWKGYWRGFVPCFLRAFPANAMALVAFEGVMRSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C916</accession>
    <name>X0C916_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C916"/>
    <dbReference type="HOGENOM" id="CLU_3351139_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="37" mass="3995" checksum="4017B64A9D76C202" modified="2014-05-14" version="1">MVGNPYPRHCVHATLQVPLFGVITAQSQGIVGMCQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAH3</accession>
    <name>X0CAH3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phenylalanine ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the PAL/histidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAH3"/>
    <dbReference type="eggNOG" id="KOG0222">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014801_3_1_1"/>
    <dbReference type="OrthoDB" id="10051290at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016841">
        <property type="term" value="F:ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.20">
        <property type="entry name" value="Phenylalanine ammonia-lyase 1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005922">
        <property type="entry name" value="Phe_NH3-lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023144">
        <property type="entry name" value="Phe_NH3-lyase_shielding_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01226">
        <property type="entry name" value="phe_am_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="HISTIDINE AMMONIA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="746" mass="81634" checksum="BE603C1048920A46" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAJ4</accession>
    <name>X0CAJ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6987 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658464">
        <property type="protein sequence ID" value="EXK79682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAJ4"/>
    <dbReference type="HOGENOM" id="CLU_3032442_0_0_1"/>
    <dbReference type="OrthoDB" id="3937590at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054256">
        <property type="entry name" value="DUF6987"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39461">
        <property type="entry name" value="LEA DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G04920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39461:SF1">
        <property type="entry name" value="LEA DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G04920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22485">
        <property type="entry name" value="DUF6987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6987" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="55" mass="6001" checksum="A1CD0F5446A57C4C" modified="2014-05-14" version="1">MPHAKKELNPLWALLAVPLFQIIAAIELLLDGMLGLVGRLLHGDVISSLTGRKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBS6</accession>
    <name>X0CBS6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable electron transfer flavoprotein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_06327</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9 10">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBS6"/>
    <dbReference type="eggNOG" id="KOG3954">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034178_0_0_1"/>
    <dbReference type="OrthoDB" id="1715808at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000041">
        <property type="entry name" value="Electron transfer flavoprotein alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000001">
        <property type="entry name" value="Electron transfer flavoprotein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153:SF1">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 9 10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="11">
        <location>
            <begin position="35"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="262"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="276"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="293"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000089-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK91601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="347" mass="36199" checksum="15589EF6A6539758" modified="2014-05-14" version="1">MLPTAKRVLAQRATGLMARAHAYSLGAQRQRLQSTLAILEQKDGVLNHSSLSAFTAAKKLGGPVHGFIAGNNIKPVAEEIAKAEGVEKIIAVDNSAYEKGLPESYAPLLVENIKKGGYTHVIAGHTAFGKSVMPRVAALLDSQQISDITAIENENTFVRPIYAGNAIATVESSDSVKVITIRGTAFAAGPLEGGSATVEDGVDSKPESPTEWVSEDLAKSDRPDLSTASRVVSGGRGLKSKEEFDKVMLPLADALGAAVGASRAAVDSGYADNSLQVGQTGKVVAPQLYMAVGISGAIQHLAGMKDSKVIAAINKDPDAPIFQVADVGLVGDLFEKVPELTEKVKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCH1</accession>
    <name>X0CCH1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCH1"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF154">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_2G04560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="32848" checksum="250E9E36273D979F" modified="2014-05-14" version="1">MAPFKGFNPETDIPSLTGKVILITGGTSGLGRSAILTLASHNPSHIYFTGRSSTSASSLISTISPVSATFLECDLTSIASMRSVAKQFTHDRLDVFIANAGVMAVDGLTQDGLELQFGVNHVGNATLLMALLPIMQKTAEKGGEVRFVSVTSLGYAGHPKKGIEFETLHSLQEHLPFGTWSRYGQSKLANIVLAKELERRYPAIKSVVVHPGVIATNLVTGLGFWKRMFVYVTNPSMMTVEHGGYNTAWAAAGDVKRDETVAFYEPVGKANKGDDMCFSEELGKKLWEWTEEKIESVKQSQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD58</accession>
    <name>X0CD58_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658440">
        <property type="protein sequence ID" value="EXK80592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD58"/>
    <dbReference type="eggNOG" id="KOG1206">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040078_3_0_1"/>
    <dbReference type="OrthoDB" id="60204at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044594">
        <property type="term" value="F:17-beta-hydroxysteroid dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078:SF57">
        <property type="entry name" value="DEHYDRATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078">
        <property type="entry name" value="PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peroxisomal multifunctional enzyme type 2-like N-terminal" evidence="2">
        <location>
            <begin position="19"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
            <begin position="174"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="309" mass="33857" checksum="71D0908901104EC0" modified="2014-05-14" version="1">MSGPGVGFEYPPVKVTWLQRDVLLFANTIGATADELHFLYEFHPKFTVFPTYPVILPFKKDSQEVVDYYKESKAVQITGVPKLDYTRVVDGQRKIQFLKPLPTTSAGRNFETRQKVIGVYDKGRPGTVLETQTDLVDVESGEVHTRVTSSGFFIGQGNWGGPKGPTTENYPPPKGKAPDATIEVQTNAETALLYRLNGDYNPLHADPEPGQKMGFGGTIMHGLYSWNSTAHSLLKELGGGDPANIKEYQARFASPVRPGDKLVTHAWVTGVKQDGWAEVRFVTQVAGGKVVLSNGLALMKVTSQGMSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE01</accession>
    <name>X0CE01_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial fission process protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial 18 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_05712</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE01"/>
    <dbReference type="eggNOG" id="ENOG502RZGV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053720_0_0_1"/>
    <dbReference type="OrthoDB" id="424969at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019560">
        <property type="entry name" value="Mitochondrial_18_kDa_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001:SF2">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10558">
        <property type="entry name" value="MTP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK92640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="282" mass="31532" checksum="AF5D641E2B741AA7" modified="2014-05-14" version="1">MSWWGKSKDPKPEEKKTEAAQIKDTIVEKLPSKDQLPESVQKAVNKTGRDGNVFDDITDGYGPDSTDTNFRYAAYATRIRTILLSAHRYVAYTSDIGESFRPVAHPNLVRAAYGVSWLYLIGDVSYEGYKSYWHNQRVLNPKVQLSPRQEKVTGLPATETRPIEPGTVPPLEDYRTVMVQRAIFQSVASMGLPAFTIHSVVRYSGRAMKNMKNQVIRTWAPIGLGLAVVPFLPAMFDEPVENAVEWAFHKGFETFGGKAAVGNAPTTGREDLLAKRPKEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE03</accession>
    <name>X0CE03_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14629</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658434">
        <property type="protein sequence ID" value="EXK80857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE03"/>
    <dbReference type="HOGENOM" id="CLU_1378189_0_0_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK80857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="198" mass="21052" checksum="D14D536483C02C05" modified="2014-05-14" version="1">MSTGAPFEVSAKSPSQSYSDLAPGLCSDVIKLPRKAGAHCQASTTALPQATLPVLAPRPQQTHHAEHADTAVQVFPTVQALEKTNTRASLACDRCRKQKAKCDETKPCTACKRKGTECKYRDTVSKATDKAQADILEIIGSVHTTLGSVIRYLGQFEGRLNEMESLLLGSPSVTNGASTDPANFIATPVPQRSPSDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE70</accession>
    <name>X0CE70_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_07618</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE70"/>
    <dbReference type="HOGENOM" id="CLU_009600_9_2_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF8">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="83"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="227"/>
            <end position="230"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK89523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="558" mass="61291" checksum="DB2A38B00D7E7DE8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFE8</accession>
    <name>X0CFE8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFE8"/>
    <dbReference type="HOGENOM" id="CLU_2775991_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="69" mass="7544" checksum="0CF456FA861BE814" modified="2014-05-14" version="1">MASDGLLYGISMLRSESNLPRRWKHVGGSQHADKVNPLESNDINFATAMPTIMTFPIGEWICDGVGHGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFR5</accession>
    <name>X0CFR5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFR5"/>
    <dbReference type="eggNOG" id="ENOG502RNSI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004604_0_0_1"/>
    <dbReference type="OrthoDB" id="4889313at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="686"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="720"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="967"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="792"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="829"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="896"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1073"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1092" mass="121623" checksum="8A8A6E2BCA865361" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHE2</accession>
    <name>X0CHE2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHE2"/>
    <dbReference type="HOGENOM" id="CLU_3175439_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="42" mass="4659" checksum="85AAF081B5D217BB" modified="2014-05-14" version="1">MRYEIMRGEYQSDSGVYGKGNPGFMPSGLMSSEYYKAPACSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHL7</accession>
    <name>X0CHL7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenine deaminase</fullName>
            <shortName evidence="7">ADE</shortName>
            <ecNumber evidence="7">3.5.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Adenine aminohydrolase</fullName>
            <shortName evidence="7">AAH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AAH1</name>
        <name evidence="9" type="ORF">FOQG_04902</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenine + H2O + H(+) = hypoxanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:23688"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.2" evidence="7"/>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHL7"/>
    <dbReference type="eggNOG" id="KOG1097">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039228_7_0_1"/>
    <dbReference type="OrthoDB" id="272271at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000034">
        <property type="term" value="F:adenine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006146">
        <property type="term" value="P:adenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043103">
        <property type="term" value="P:hypoxanthine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009168">
        <property type="term" value="P:purine ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01320">
        <property type="entry name" value="ADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000039">
        <property type="entry name" value="Adenine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01962">
        <property type="entry name" value="Adenine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028892">
        <property type="entry name" value="ADE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114:SF6">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="8">
        <location>
            <begin position="14"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK93656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="353" mass="39845" checksum="5267E5894B5A7B9A" modified="2014-05-14" version="1">MCNSQFHSFLKALPKVEQHLHIEGTLEPELLFSLAEKNGIKLPEDPVYESADKLRERYGRFTCLDDFLHYYYLGMSVLITENDFETLAYQYFQRAASEKVRHAEIFFDPQAHTARGVSYDTVVAGLTAAKRRAQKELGITVELIVCILRHLPVPESHALVDTLLDRGHFNDGTLTGFGMVSSEKAFPPELFTEVYARVAKTGTHLTTHAGEEAPPSFITASLEHLKVSRIDHGLAAAQDPELLKRLAANRTLLTFCPWSNVALCNLPELADAPVRKFLDAGVLFSVNSDDPAYFGAYVQEVYCRVQDTFSLSVKDWAWIVRGAVEESWCSDERKQEILKELEQVLEEYKDLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHR3</accession>
    <name>X0CHR3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHR3"/>
    <dbReference type="HOGENOM" id="CLU_2250261_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="104" mass="11885" checksum="2240EBB88F8AD920" modified="2014-05-14" version="1">MSNLRHPRFSILILEEDREGIWSKTLRTRDLNQLSSLLQESSFFYDLGNLTQRLNVNLVGHFTYKQINKFVNNIYQLLLGASVSSHRSLVLCSLCPSGVGLRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJL7</accession>
    <name>X0CJL7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJL7"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1627129_0_0_1"/>
    <dbReference type="OrthoDB" id="5084558at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936454" evidence="1">
        <location>
            <begin position="20"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="161" mass="17058" checksum="D2028D215ECCC044" modified="2014-05-14" version="1">MISLRDIGLLLLAAPIAMAAPKAPSEVTIKTLPFSKPEGTSKAPSTSAVASPASDAAQKAACQLPLRFTNFALYSDTGCKNVIFDPFMLTWDPCKGYQWTNALANGVIFQSMRWTGGSNAQDFYACQQGFSCNANVARISQSTNVCSSGGGLHFDKLAVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLS1</accession>
    <name>X0CLS1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secondary metabolism regulator LAE1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLS1"/>
    <dbReference type="eggNOG" id="ENOG502S6PS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_7_1_1"/>
    <dbReference type="OrthoDB" id="184880at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="44467" checksum="FF519B40099EA8FA" modified="2014-05-14" version="1">MLSRGVEAHCDSWKRNSKDMGAHDTEGKRASPRSSPPLQEKSDPVGHDEQDTDPTLDDNQGLLHGNAVIEAGGSDEDGEFSASDFDPEDSSSLRSSSTSISSSILEHSYQNGRRYHRYRHGRYPLPNDEAEQNREDMLHAMMLEATDGRLFYAPVRENPQRIADLGTGTGIWAIEIGEKYPSAEVLGLDLSPIQPTWVPPNVKFYVDDIEDEWLNGDDFDFVHLRNMIPILKSPVTLLKQVYANMKPGAWVELQDVDGQVHTDDNSIPDDWPLKRFTEIILQAFALYETNAHAAVFGGQYLAEAGFVNIKHNFIKLPYGTWPKDKVMRLVGMYYRTACEEFFPAIGNLHFPQLGWGKDEMEVFFAECRQSMRDPKVHAYGKMHFWSGQKPLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMJ4</accession>
    <name>X0CMJ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMJ4"/>
    <dbReference type="eggNOG" id="ENOG502SCNK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052827_4_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF6">
        <property type="entry name" value="THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="171"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="268" mass="28974" checksum="AC83C3DB77C20181" modified="2014-05-14" version="1">MQVSKLLRPISTQLPSFYISRSAPHSRVRNRIIGPPVNTTLSHISIKAFSSAKMEFPPFHNSILCPALDLVPENAPPDLFASELSFFASHPWTASLLCAPDAIPFLPSCRNPKSQAHDQLFGNTLNNSRGLRHLISYFRAPSFEVAKDPAHNITEIAVLVSVGEGVSGYPGMVHGGIVAALLDESMGTIFDLNGTLGKEARAFKTHSVTGGIDVKYLKPVPTDSVVCITAVAEEIDGRKTKVRGEMKDEKGEVLATCSSQWVALKPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN25</accession>
    <name>X0CN25_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_04132</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002786_0_0_1"/>
    <dbReference type="OrthoDB" id="361039at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1132"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1173"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="12">
        <location>
            <begin position="178"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="492"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="545"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="826"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1267"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="839"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK95576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1288" mass="145504" checksum="EC9B244A11BC9235" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN36</accession>
    <name>X0CN36_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN36"/>
    <dbReference type="eggNOG" id="ENOG502SDNG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_197715_0_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="61" mass="6694" checksum="78B9435664659E2E" modified="2014-05-14" version="1">MGPLMSVRRASEKVFNPQPNQLDNARRKLSTVTTSTVIPQANPDPTPDIEAQTPLSGFGEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP30</accession>
    <name>X0CP30_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7624 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP30"/>
    <dbReference type="eggNOG" id="ENOG502SKIF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5230484at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056041">
        <property type="entry name" value="DUF7624"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24616">
        <property type="entry name" value="DUF7624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7624" evidence="2">
        <location>
            <begin position="571"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="551"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="708" mass="78748" checksum="366C2F5A171043CB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ73</accession>
    <name>X0CQ73_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Midasin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ73"/>
    <dbReference type="eggNOG" id="ENOG502SF70">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2873061at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587:SF4">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="38886" checksum="BD0BB98E67E4F40D" modified="2014-05-14" version="1">MSSPSQQDSQKRDESQAPQSPGQGQNQQEQGNDSNPFNQNQNEGQQEEQNQNQGQGQEAQQQQPGQESESKPEDAKDESKPDTENAKAETPGDKEDKPEQPGQARPEEPKAEESKPDESKPEEPKPEDSKPEEAKADDKKPEEVKKEEDEAESKPEQAKAETQKTAQEAKPKQKRQPVKEESEDEDDSEDDDDDFDSEDDSEEDSEEDSEDDESESESEEENEPATPPQQAEPGRKGGRRGNAKAADVRRRRPAWLDEESDDEGRKQFSRQDQQLQQQRQQQQMQQQQQQQQQQQQMQQQQQQQQGGGGKSDALSLHLELNLEIEIELKARIHGDLTLALLEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRA2</accession>
    <name>X0CRA2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADP-dependent 3-hydroxy acid dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05521</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRA2"/>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000047">
        <property type="entry name" value="NADP-dependent L-serine/L-allo-threonine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK93404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="29291" checksum="E8E3DC5DFD9D175B" modified="2014-05-14" version="1">MESLKGQTAFITGASMGIGEAIAVALAEQGVNLALVSRSKDKLETVRTNITSKFPKVKVGVYPLDLQHQADVEKAVKAAISEIGQIDILINNAGLALGAPGRFWEIPADQITQMSGTNINGVMYTTHAILNHSMWERKKGTIINISSVTGLECPPFNGEAVYHASKAFLEGFTNSLRMETAGSDIRVLVLRPGCVVTHFHLQRVQYDQGAMDEFFQGYDPLVAEDLAQSVLYMLSLPSRISIKALDCVPTAQRALTRFDREWKSRHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRI3</accession>
    <name>X0CRI3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosine-protein phosphatase non-receptor type 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRI3"/>
    <dbReference type="eggNOG" id="ENOG502RVW6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029046_0_0_1"/>
    <dbReference type="OrthoDB" id="3921198at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="631" mass="70086" checksum="57BA6C66FC33DAF3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRN4</accession>
    <name>X0CRN4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl-CoA hydratase/isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04807</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRN4"/>
    <dbReference type="eggNOG" id="ENOG502QS1J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_3_1_1"/>
    <dbReference type="OrthoDB" id="1696280at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF75">
        <property type="entry name" value="ENOYL-COA HYDRATASE_ISOMERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="36625" checksum="BD390CEE5ED165C0" modified="2014-05-14" version="1">MPRCPSQIHHVLTPGISTSRGVFLSRPSTPRSYTNLLYHPTTLTLPHILSSHSQHKMSILFTLPIAKCGAHPGGTLTCTEPSPRVYLLTLLSPPDNRLTTPVLKAFLNALDIIEFGYPHGVVATTSGIPKFYSNGLDLEHAVATDGFWPLLYDVWARFLTYPMPTVALMNGHAFAGGLMLATAQDYRLAPTPRGFLCLNELVFGAPLKPAMSALFRIKYSHSTYRSLVLEAKRFTGEDALAAGIADGLAPKGLEDLLNFIKEKELIDKSKSGVYGVLKMEMYAGLVEFMRGPAMEAHEQRFEEAQSREGERKEFGKVWYEQWLKDTKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS42</accession>
    <name>X0CS42_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS42"/>
    <dbReference type="eggNOG" id="ENOG502RA50">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2306192_0_0_1"/>
    <dbReference type="OrthoDB" id="4988584at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="109" mass="12695" checksum="906D0495D44C03B3" modified="2014-05-14" version="1">MSTRRLLNALISGRLRPGLKPGRLTLIVRKDHTKWECIEKVGHNDQGEPLECGEVMKMTEQVCKKCWCIRRVGAAALTEDEMYLGMLARITRGINEWWEYYPELQESEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS69</accession>
    <name>X0CS69_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS69"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="9942608at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14372">
        <property type="entry name" value="CUE_Cue5p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000064">
        <property type="entry name" value="Similar to CUE domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041807">
        <property type="entry name" value="Cue5/Don1_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461:SF5">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="79"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="416" mass="45773" checksum="76FA70A7E9BB46AE" modified="2014-05-14" version="1">MSAPGETNKATAESGPESPTTARPLDLDDDDVQESGVLDSNTTPAAATNTTTTQTQAQAQAPSPTNETAPPKPPRPVSEAQKNETILKEAFPSVELSVIKAVLRASGGRVEPAFHALLEMTDPDAAQNEPADEVPPPQPPRPQNRSQMSQLEADELYARQLAEHYDNVGAYESRTANRGQRQGQRGQDEWGDDREHSFIDDDLPVIRENLRKGFFETQEKVNGWITNIKKKIEENFDESEEQTQRQGEPFRRPGESSRRSGDYDRYDADPQVLSDDFAGMKFSSDGTPVSRPMANTGMYKPPPPSASPKPSNGRRVGFKEETEEINMYDSSPRVPPKDAAPASGTRGSKWQPMSAVEPSPIAENDPFSLGDSEDERETHQKTKDDKTDDSERLKKATAEAMADSLSESKDTEAKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUQ7</accession>
    <name>X0CUQ7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUQ7"/>
    <dbReference type="HOGENOM" id="CLU_3087290_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="52" mass="5991" checksum="538D1BD7F37A7397" modified="2014-05-14" version="1">MSTVLVRVSVVTCQREFDICHNFMIPHNGAGVLEYEGVTEYWSLELELNSWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUR1</accession>
    <name>X0CUR1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_04630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUR1"/>
    <dbReference type="eggNOG" id="KOG2655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000328">
        <property type="entry name" value="Septin spn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="16"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="294"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="301"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK94619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="383" mass="43473" checksum="6221428FB9DC2A70" modified="2014-05-14" version="1">MSSMGKMIRRKKNVKKGIQFCLMVCGASGTGRTTFVNTLCGKSVLDHKESDDAGSAHVEDGVKIKPITVELELDEEGTRISLTIVDTPGFGDQIDNEASFSEIVGYLERQYDDILAEESRIKRNPRFRDNRVHAMLYFITPTGHGLRELDIELMKRLAPRVNVIPVIGRADSLTPAELAESKKLVMEDIEHYRIPVYNFPYDIEEDDEDTVEENAELRGLMPFAIVGSEEVVEIGGRKVRARHYPWGVVEVDNPRHSDFLAIRSALLHSHLADLKEITHDFLYENYRTEKLSKSVEGASGNADSSMNPEDLASQSVRLKEEQLRREEEKLREIELKVQREINEKRQELLARESQLREIEARMQREAASQATGTPEPNGEEPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWX3</accession>
    <name>X0CWX3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWX3"/>
    <dbReference type="eggNOG" id="ENOG502RX75">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008809_0_0_1"/>
    <dbReference type="OrthoDB" id="5340195at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF3">
        <property type="entry name" value="FORMYLMETHIONINE DEFORMYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="682"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="804" mass="90834" checksum="F92CC95324830E4A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXI9</accession>
    <name>X0CXI9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXI9"/>
    <dbReference type="HOGENOM" id="CLU_2996546_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="57" mass="6391" checksum="E818C57F0C64205A" modified="2014-05-14" version="1">MNAGRRLPVPDGWNLLPRLPHNFGYLSGVTGDRSAKLQQVAGSDEKRTVWSVAQWQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZT2</accession>
    <name>X0CZT2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZT2"/>
    <dbReference type="eggNOG" id="ENOG502RKIQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2960823_0_0_1"/>
    <dbReference type="OrthoDB" id="10449073at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="59" mass="6395" checksum="94F7679BB5781AE4" modified="2014-05-14" version="1">MQGRKKPVVLLSGPREGSDAEQHAGDWVGPGKADPRRDDVPSSQQRGELAEGGICRWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0D000</accession>
    <name>X0D000_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D000"/>
    <dbReference type="eggNOG" id="ENOG502SHSN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_7_4_1"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="105"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="743" mass="82744" checksum="B60AAAFD2F87FDC4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1Y9</accession>
    <name>X0D1Y9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Patatin-like phospholipase domain-containing protein</fullName>
            <ecNumber evidence="7">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_08437</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Lipid hydrolase.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable lipid hydrolase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PLPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1Y9"/>
    <dbReference type="eggNOG" id="KOG2214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009031_2_2_1"/>
    <dbReference type="OrthoDB" id="15478at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07232">
        <property type="entry name" value="Pat_PLPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF66">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE PTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5 6 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="9">
        <location>
            <begin position="361"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="44"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="726"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="6">
        <location>
            <begin position="392"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK88662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="770" mass="87312" checksum="722D2540B2775AC9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D280</accession>
    <name>X0D280_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxisomal biogenesis factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D280"/>
    <dbReference type="eggNOG" id="KOG4444">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017002_3_0_1"/>
    <dbReference type="OrthoDB" id="45930at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006966">
        <property type="entry name" value="Peroxin-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080:SF1">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04882">
        <property type="entry name" value="Peroxin-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXL00537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="532" mass="58639" checksum="3E0353D484E2ED37" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9C9</accession>
    <name>X0D9C9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tropomyosin-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9C9"/>
    <dbReference type="eggNOG" id="KOG1003">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104738_0_1_1"/>
    <dbReference type="OrthoDB" id="128924at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000114">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.340:FF:000001">
        <property type="entry name" value="Tropomyosin alpha-1 chain isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000533">
        <property type="entry name" value="Tropomyosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19269">
        <property type="entry name" value="TROPOMYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00261">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="18821" checksum="B33F4EDDA7BF8D47" modified="2014-05-14" version="1">MDRIKEKMNQLRLEADEASGKVEELQSKVKVLEQENLSKEQEITSLQHKNNLLEGEVEKLENAVKDFKKAADEGQQHGTQNETLQRRLQLLEEEAEDADKTLREANEKLRQTDVKAGHFERKVQALENERDQWESKYEEMSQKYNALQKELEELQAEIGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0DAX2</accession>
    <name>X0DAX2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycolipid transfer protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DAX2"/>
    <dbReference type="eggNOG" id="KOG3221">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079400_0_0_1"/>
    <dbReference type="OrthoDB" id="205255at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902387">
        <property type="term" value="F:ceramide 1-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902388">
        <property type="term" value="F:ceramide 1-phosphate transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3520.10:FF:000001">
        <property type="entry name" value="Pleckstrin domain-containing family A member 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219:SF25">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glycolipid transfer protein" evidence="2">
        <location>
            <begin position="101"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="274" mass="29786" checksum="2F86680DC98A489A" modified="2014-05-14" version="1">MPLLHRLEPLTRSPELDPSCIAPCLNLPAKGQLSLTASTFNDTSSFLTFLLPSNTFSFSSSFTSPSSIIMSAVYPPGGTIVQSLKRTFADVPVDEANGNAVSTVEFLEASESLTTIFDAIGGVAFGPVKKDILGNVEKLRARHAAAPAESATVQDLVRNELKTGKHTATEGCLWLIRGLDFTKQGLEHNVQNPSVELSDSFRDAYGNTLKPHHSFMVKPIFSAAMSAVPYRKDFYAKLGDNPEKVQADLEAYLASFSKIVAILKEFINSKEAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0DC69</accession>
    <name>X0DC69_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Transcription factor Pig1p</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_00743</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DC69"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003487_0_0_1"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="134"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="181"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXL00680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="923" mass="102561" checksum="DE4A36890E4FC703" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCB6</accession>
    <name>X0DCB6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06078</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCB6"/>
    <dbReference type="eggNOG" id="KOG1299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013933_3_1_1"/>
    <dbReference type="OrthoDB" id="10266265at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.830.10:FF:000002">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK92177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="577" mass="64610" checksum="A54E33682D917EEE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0DEP1</accession>
    <name>X0DEP1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Vacuolar protease A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_05226</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DEP1"/>
    <dbReference type="SMR" id="X0DEP1"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_3_4_1"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000036">
        <property type="entry name" value="Vacuolar aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000002">
        <property type="entry name" value="Vacuolar aspartic proteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="8 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12 15" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738265" evidence="13">
        <location>
            <begin position="18"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="14">
        <location>
            <begin position="86"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="117"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK92987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="396" mass="42777" checksum="A9050D850C47A8A3" modified="2014-05-14" version="1">MKGALLTAAALLGSAQAGVHKMKLNKVPLADQLATNSVEDHLQSLGQKYLGASRPKNAADYAFATNTVNVEGGHPVPVSNFMNAQYFSEITIGTPPQSFKVVLDTGSSNLWVPSQQCGSIACYLHSKYDSSASSTYKENGTEFEIHYGSGSLSGFVSNDVVSIGDLEIKDQDFAEATKEPGLAFAFGRFDGILGLGYDRIAVNGMVPPFYQMVNQKLLDEPVFAFYLDDQEGESEATFGGIDKSKFTGDIEYIPLRRKAYWEVDLEAIAFGDEVAEQENTGAILDTGTSLNVLPSALAELLNKEIGAKKGYNGQYTIECDKRASLPDITFNLAGSNYSLPATDYILEVQGSCISTFQGMDFPEPVGPLVILGDAFLRRYYSVYDLGKNAVGLARAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DFH3</accession>
    <name>X0DFH3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DFH3"/>
    <dbReference type="eggNOG" id="KOG4453">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031477_2_0_1"/>
    <dbReference type="OrthoDB" id="5673at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037997">
        <property type="entry name" value="Dgk1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303">
        <property type="entry name" value="CTP-DEPENDENT DIACYLGLYCEROL KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303:SF1">
        <property type="entry name" value="CTP-DEPENDENT DIACYLGLYCEROL KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="400" mass="44218" checksum="8D4AA17B35F1D704" modified="2014-05-14" version="1">MSFRSKIPETPRVISPSPTPSERDAADYMGPVTRSAARRRTPTPQPLEEEPDEDLPEPPEFRRARTRSRSPIDTQAVTRLTRRTSTAAKAGKMSKDTIPEEQTTSNGALSSNGKGKSTTSNGHLAPPQPTTPVGWSWRDFSRSPSPLGLIPIHRHWRTFVHKHEVPRKVLHVSIGFFVIWLYVTGTQTTSVTPWLMSALIPIAATDWLRHRYASVNRLYVKVLGALMRESEYSGWNGVIFYLLGAWIVLYGFPKDVGIMSVLLLSWCDTAASTFGRLWGRYTPRLRRGKSLAGSTAAFLVGVGTSYFFYGWLVPTVGPFPGDENFLFKGFLSLPKTICEAVGVSKEQTTISGALALGVMSVWSGFVASASEVVDIFGWDDNLTIPVLSGFGIWGFLKIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0DZ41</accession>
    <name>X0DZ41_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DZ41"/>
    <dbReference type="eggNOG" id="ENOG502SXHQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075359_0_0_1"/>
    <dbReference type="OrthoDB" id="5087186at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="26124" checksum="84A8E207B18B7061" modified="2014-05-14" version="1">MSESRYHEGLEVYSDGAAHAPEVNPHGVYNQGSKDPISGYVQVVEARKGPFGLSILSLCALVAIITAVIVGAGVGGGLGSALADCKNSQVSEAPAASAIQTSACPTLTASASETTATTESKFYEPKPADQVTNLTLPDACSQPNGKDDYTTTNGYGFTYTCGFDYPGNDIVPILAYTAFDCMHACAMYTEINSGKENATLCDSIAFNREMAKNYEVKGGNCWLKTGTRDLFPASDLMPTFLYAKRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0DZE7</accession>
    <name>X0DZE7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02028</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DZE7"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_3_1"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19120">
        <property type="entry name" value="AKR_AKR3C2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044494">
        <property type="entry name" value="AKR3C2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="27"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK99507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="300" mass="33281" checksum="CDE7F7AE367FF433" modified="2014-05-14" version="1">MNSTNTASAITAMKLNDGNEIPMIAYGLGTANFKKGGRTDYDENAFNCALTAIKSGFYHLDGASAYGNEEELGAAIRASSVPREKLYVVTKLNGWKKQDVQNAFNTSMKKLGLDYVDLYLIHAPFFAEKAEDLQEAWATLEAIKGSGRAKSIGVSNFIQEHLEIILATAKITPAINQIEYHPYLQHGNLVEYHHKNNIALSAYAPLTAIIRARPGPVDALYANLARKHGVTEGDIALRWCIDQNIVAITTSSSEERLKSHMANVWSFKLASEEIEGISMMGKQKHFRAFQNQWIAEGDWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0E2I7</accession>
    <name>X0E2I7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tetratricopeptide repeat protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_00669</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E2I7"/>
    <dbReference type="eggNOG" id="KOG2002">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003008_0_1_1"/>
    <dbReference type="OrthoDB" id="343875at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031101">
        <property type="entry name" value="Ctr9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027:SF2">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="799"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="842"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="979"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="420"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="979"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1058"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1103"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1118"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1141"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1178"/>
            <end position="1187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXL00528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1212" mass="136755" checksum="46CB0E63A82117CB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0B349</accession>
    <name>X0B349_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_18697</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979482">
        <property type="protein sequence ID" value="EXK76565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B349"/>
    <dbReference type="HOGENOM" id="CLU_009665_12_0_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="599"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="633"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="716"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="7"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK76565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="783" mass="86640" checksum="2348A095523114A6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5C6</accession>
    <name>X0B5C6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979429">
        <property type="protein sequence ID" value="EXK76966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5C6"/>
    <dbReference type="HOGENOM" id="CLU_047146_0_0_1"/>
    <dbReference type="OrthoDB" id="4777915at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="437" mass="51546" checksum="8F1C97312E2A5D93" modified="2014-05-14" version="1">MDPNLELYKSVLHLGVADRRQRLQHLPRSELSRLHIIVTREKQAQRLEELIAGRDLVQLALTDPSEVIECTPLKYALLGRTTYSYDEDEMVSRITNNIARSSQILVDTIARFDQVTKPFRLDALKLVYCDIYYVDGGNATLQEIFEARLQEEELQTPAEQARELVRYNALKRARRNAKWMIPAMERLSEEEQAQPTHEYMETLQRIWKQASPAPPPWIQKILDTRQQWGFIYYLSREANQKYGSDWESVWASIKDSMAPPAERNMGDATWWSIHCQGEDNRRKVLEPLLTEDWPKFYPNDSLAEDEDFRRHFKQYREENANRLSPGILYNTFITIPIKLLPDLSEDDKFGENHTLNPYWVWAYDADWDPSGEVPTSGGEKYQGRVRVAIWSLSAWFYAARWEGISLRDMWLKAQEHPDKVWVCYTKRLEEWEHEPFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6L5</accession>
    <name>X0B6L5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658576">
        <property type="protein sequence ID" value="EXK77760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6L5"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_885789_0_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="314" mass="33815" checksum="D029D03D72251609" modified="2014-05-14" version="1">MALSDSRTALEDLAIVSKDEYKETTKIIRNGLSGTGANHSSEEEMLHGFRYGMWIKTFENIPIILENFSRLPHITDYTINKRGDRILHMANDAFHLADSLVSHGADLNFTTLSCSHLTLSNPTTILGHVIASDARSSIARLRYLLGSPLMRDGLHLIVGPARQRSALHRAAAAHIDVEFHGTDAAEAAELHWADVDWSANREIMNEILRHFNGPEQLNAVETSTGLSPMHLAVLAGNEAAVSLLLDHGARSDVPSVGGQGATAADTALGIQMGGLSMIEEIGRPGREEVAARKQCSNLLNPATQSAAQAQPALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6R6</accession>
    <name>X0B6R6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979375">
        <property type="protein sequence ID" value="EXK77825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6R6"/>
    <dbReference type="eggNOG" id="ENOG502RK0M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043830_0_0_1"/>
    <dbReference type="OrthoDB" id="2520703at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="494" mass="56133" checksum="35140CEC82B26119" modified="2014-05-14" version="1">MARTRLQKSTTDYFSKLSPEILRSIFSYFCPHCCNEYQWPFGAPPESKRVQDNTTLYNLCLVSRYFRPFAQEILHHSFDPYYTSLDAPNPWERRLEPFLQTIASRPDLARSVKTVFLKVRLVESLDFDQSRKVFDTCARTFGSSAQDVSDKRHDPRSSTIKRAFFRGTRPPKNMRSRDFIPTAAGQLLSILVSILPNLDHIGIEEDRRWQLDVSPVTLDVLGINSIPLKTLETDYSLPNLLARTPELETLVTSASDWFPNMPCLRNLHIRPRNAVQATTLGHLLSACTGTLSAFSYTSFDSNIVGVVSLLDEPRFHASLETLHLDIRHYSDRGNHEMPGLKQFTRLKRLFLHTYLLYGPKYPTCCEGNCVFKSLVDILPPSIISLELSERTQTPYGRMQNDLLILAKNVAVDFPQLKEIQSNADNVCDEYPEALFKSVGVDLIHQDSTLCCWINTVFRIMSTVNYAYDSDYDERGCGGGGCGMPLPGELSDEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6Z3</accession>
    <name>X0B6Z3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">D-serine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-serine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_17396</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the conversion of D-serine to pyruvate and ammonia. May play a role in D-serine detoxification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13977"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="EC" id="4.3.1.18"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:13978"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DSD1 family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.18" evidence="11"/>
    <dbReference type="EMBL" id="JH658559">
        <property type="protein sequence ID" value="EXK77905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6Z3"/>
    <dbReference type="eggNOG" id="ENOG502QRZ0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031639_0_0_1"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036088">
        <property type="term" value="P:D-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000016">
        <property type="entry name" value="D-serine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0216">Detoxification</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="14">
        <location>
            <begin position="326"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00066349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00075219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK77905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="461" mass="49950" checksum="44254FFC15C30B28" modified="2014-05-14" version="1">MAIPQRQTPPIEELRQFYVGKSIHDVPKPAVILDKTRVTRHCQSMLKAVDTLGLGFRAHVKTHKTIEATRLQIGQGSGDVKLIVSTLAEIEHLLPLLKEYKDAGRRLDILYGLPLPRSQISRLASLGSELGQGSISVLIDHPTQLGSVKAFSQHSKFPARVFLKVDTGYHRAGLPPTAMNKNGLIEALAELEAHGEAELLGLYSHSSLSYKDSTPEQAMANLEGEIRGCLDAVNAHAHLFGKDKELVISVGASPQVTAVENLVTAQGDLSPAAESLRKSIHDVTTGKPGGLQTKLELHAGVYSILDMQQVSTNSRRELGSFEDEIAISIIAEVCSVYNDKERSQPEALVAVGCLGLGREPCAAYPGWGVISQSSYKAESYRGRRLIIDRISQEHSIAAWEHAEGEDASTLPPVPLEVGQDVVIFPNHACVAGALYGWYLVVDSSEGDATKIVDVWVRASGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7C7</accession>
    <name>X0B7C7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetylesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17264</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979368">
        <property type="protein sequence ID" value="EXK78060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7C7"/>
    <dbReference type="eggNOG" id="ENOG502RS04">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015101_4_2_1"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050592">
        <property type="entry name" value="GDSL_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45642">
        <property type="entry name" value="GDSL ESTERASE/LIPASE EXL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45642:SF139">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936176" description="Acetylesterase" evidence="2">
        <location>
            <begin position="23"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="31680" checksum="12CA68FB3224F118" modified="2014-05-14" version="1">MLSKLLFAAMGSILVQSAAVHAAGSIGYLFTFGDSYSQTGFDPNGAKPSAANPLGNPPFPGWTAAGGANWVGDIVKEQNNSLVLSYNFAYGGATVDANIVKPYASTVLSFVDQVNQFSNSVGKHPAGTSWTAQNTIAGVWIGVNDVGNSFYLQDADAVVEKATTRYFELLQVLYKAGLRKFVLLSVPPTELTPLMIQQGADSNALLVKAIKLYNSKLASKLSAFKKANSGVKTLLVDTSVSFKKAINNPKAYGAPDATCYNSDGKSCLWFNDYHPGIAINQLVAEQVANELEANGFGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB36</accession>
    <name>X0BB36_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979630">
        <property type="protein sequence ID" value="EXK76038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979630">
        <property type="protein sequence ID" value="EXK76039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB36"/>
    <dbReference type="eggNOG" id="ENOG502RVS3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1090042_0_0_1"/>
    <dbReference type="OrthoDB" id="5082755at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="255" mass="28754" checksum="6935A4D37D623BD3" modified="2014-05-14" version="1">MPKSQAKKKPPAKGLDTSKSNAKAGTPAPYEFSGHDSINISSFDLAQAQQSLEHSDVPSMRPQLKSPRQYPRELNHPMHWQLLQHEFLISRHKALRSSVPSHPSTLPALEPTSKTPETLPLDKPASNLRPPSPGESSTASTKPPVPEIRLSPPEETSKTPRQPRPPIENPAYPWEEEELQALEDLRNEQRRLHEETLNAMGQMAYWSFRAQRAANRVKKTMCELRSYMDEVLAEQEEVQGHNENECNVVPPSLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBM4</accession>
    <name>X0BBM4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658748">
        <property type="protein sequence ID" value="EXK76208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBM4"/>
    <dbReference type="HOGENOM" id="CLU_3279561_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="41" mass="4742" checksum="0C62F65E4330E25C" modified="2014-05-14" version="1">MQSDWAKQCLYKRLAGTAIVQFKKSQRKSVEVEVEVEVEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC20</accession>
    <name>X0BC20_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979618">
        <property type="protein sequence ID" value="EXK76059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC20"/>
    <dbReference type="HOGENOM" id="CLU_127786_0_0_1"/>
    <dbReference type="OrthoDB" id="10264507at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="144" mass="16780" checksum="7F1079B74DA0287B" modified="2014-05-14" version="1">MSLVFCCDAVEPYRPQYLSHQAKFNKFMSWASFPRISTPENGDGASHDLIQLSPSYAVQLVRQVNYGPLESKRYFIPTDGTESDFVEVIENDLIQANFQKVNTYKNYKCQDHNKFFEVNIYQKDPINKHHWRVNIARPADSIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCD3</accession>
    <name>X0BCD3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PiT family inorganic phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658459">
        <property type="protein sequence ID" value="EXK79810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCD3"/>
    <dbReference type="eggNOG" id="KOG2743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_2_1_1"/>
    <dbReference type="OrthoDB" id="272672at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051927">
        <property type="entry name" value="Zn_Chap_cDPG_Synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603:SF1">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="315"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="611" mass="68975" checksum="B1498E43003D6734" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCJ9</accession>
    <name>X0BCJ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979486">
        <property type="protein sequence ID" value="EXK76553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCJ9"/>
    <dbReference type="HOGENOM" id="CLU_024655_0_0_1"/>
    <dbReference type="OrthoDB" id="5355161at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="436" mass="47861" checksum="5DF6BBDD65954A12" modified="2014-05-14" version="1">MGRKSKQKSCFACVETKRRCDKRFPTCSRCLDRDSVCTYPPMPRRPPLDFPEASIAPTMDFSDAWASSAFDGGVSSLSLVGDVSVSTLLDSAFTSLDCPSWPSSLSGPSSSGIVEPSGQLTQVFGDLGWFLRPQTWTIAYHYHTPEAMPPASVFSNFIRGLQDWLSRFVKTGHNPFIHRHLYFESGYPQCIQDAYSACVISNAATSENDTIIDAISSSHISNLLNSQPVSSPMSSNTLSTRDHLARTQALLIHILLALFSSSIQRRAKAENLISLLHAWGSELWESATHDSPFTSPLQSLSSSNGGTAIAEADPVPGLYRSFILSESIRRTFLLCNIATGVYSGLKGDYTETCGGDICITAHAKFWEAPSSARWEAIARHTDPLFIYSLKGQALVTRGVGAAQVDEFARHLFTIMWGMEKVETWVVRTGDEVSIVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCR8</accession>
    <name>X0BCR8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658698">
        <property type="protein sequence ID" value="EXK76618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCR8"/>
    <dbReference type="HOGENOM" id="CLU_010595_1_2_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF31">
        <property type="entry name" value="LAEA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="37477" checksum="3E96F5234DF16759" modified="2014-05-14" version="1">MAATNGDDIVAPDDNDAGDQDSSLGDEAASSTASLRSSILDYRHENGRTYHRFKDGKYNLPNDERENERLDLQHNLFLLTFDNKLGLAPPNLPGSKVGRVLDVGTGTGIWAIDFADDHPEAEVLGIDLSPIQPSFVPVNVEFQIDDIDEEWNYSAPFTYIHSRMMNMSIQNWEDYLRKIFDNLTPGGYVELQDGDAVMESDDGTLTKEHALSKWCNLLREASDKLGRPCIPTKELRNIMDKVGFTSIVETRLKWPSNCWPKDKKYKELGAWNNENTRLVLESVTFAPLTRGLDWTIEEVNVLLADVRKELNDPNIHAYWPICSVYGRKPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD49</accession>
    <name>X0BD49_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658462">
        <property type="protein sequence ID" value="EXK79721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD49"/>
    <dbReference type="eggNOG" id="ENOG502SI2Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014625_3_0_1"/>
    <dbReference type="OrthoDB" id="3231004at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="477" mass="52645" checksum="A3211A26B02F67B6" modified="2014-05-14" version="1">MALMLAPYNGAMRLGMGFNSYTQTLCVNDVVRKPGNIPAAETDLRAAQLTQKTDAATFKSKQITAGTQQDQPQEVLDGASGTISRVVVDGQKEVSQVVSWEASFIENGSEVLKKLDVSGALSIKMAGMGQLSGKAAFVDSTDIKNADIKYLVHVKVTNQRLIADNITEFAPIDYIEPGQFTEIYGDCFISGFIEGGEFDALVTVTTEETIKKNSLSGGLELGANISGFDVAGNVDGGVENNSNDKKARTKISVTWSGGGDIRNDNIKEWTLESLKAVAMSFPDAVAVCDAVLTKYTSLRSYHEQTRKGSPLDYENAGVYTAALYDAYTDYKMMWGQIHTMIGGFNRNEIRLFTREALTIPKDFDEDMKKDYKNKESHYNERVKAREEAENAAALAPYTLNKTRDHKPIEKPLPINKFEPYKADIFGLEKAAHDCRFEMIKIVREVDAVTRDPLVACDPERISQYLSPNVFRLLLPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDJ4</accession>
    <name>X0BDJ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_15265</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JH658449">
        <property type="protein sequence ID" value="EXK80185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDJ4"/>
    <dbReference type="eggNOG" id="ENOG502SH94">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_3_2_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF13">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK80185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="523" mass="57275" checksum="B53E41DD28705A55" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BES4</accession>
    <name>X0BES4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_17951</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658620">
        <property type="protein sequence ID" value="EXK77338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BES4"/>
    <dbReference type="HOGENOM" id="CLU_045874_0_1_1"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="14"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK77338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="177" mass="20749" checksum="5C42FB03516D1AAA" modified="2014-05-14" version="1">MAKTDDNHENDSIYLVDSIQDHFVDEDGCMYFQVKWQGHESSKEWTWEPQTNLEIEGDMLVKEYFESLGKRRKRVRRSAKKQPSSSVTTCGTKRGRRNERHRTVPSGRTAKLAWKPPRGSWEHEPFHIDGCEGDSAETLMIYITWLGGHKTRHKVDVLCKKCPQKMLRYLEQYVSMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFH4</accession>
    <name>X0BFH4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979406">
        <property type="protein sequence ID" value="EXK77199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFH4"/>
    <dbReference type="HOGENOM" id="CLU_3224610_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="44" mass="4832" checksum="A727D1DE503A8266" modified="2014-05-14" version="1">MPVFSDKVPYSSSFEALTICKTSMESLFVSRRLKISCASSVGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI01</accession>
    <name>X0BI01_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cation efflux protein cytoplasmic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14099</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI01"/>
    <dbReference type="HOGENOM" id="CLU_013430_5_1_1"/>
    <dbReference type="OrthoDB" id="9944568at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF4">
        <property type="entry name" value="ZINC TRANSPORTER 63C, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="3">
        <location>
            <begin position="80"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="158" mass="17639" checksum="012E0E83DDF8EA08" modified="2014-05-14" version="1">MLEKKIRKSGHFGARLGLWDSSNTFGDICITPAALLVWKVPVASIQYIDPTLAMCIALLSMYFAYRLILAASAILLQATPSTIDTNIIKEAVERIDGVLSAHHVHIFALNENKLVCSMHVQLLSRATSGERFMEVMRQVRRILHTYGVHSATIQPEYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJ67</accession>
    <name>X0BJ67_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJ67"/>
    <dbReference type="HOGENOM" id="CLU_092842_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009267">
        <property type="entry name" value="NTP_transf_6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39166">
        <property type="entry name" value="BLL1166 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39166:SF1">
        <property type="entry name" value="BLL1166 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06042">
        <property type="entry name" value="NTP_transf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="198" mass="23043" checksum="C88159B6118DC793" modified="2014-05-14" version="1">MDAALLPINEQIARFCQAIECNKTLMTVLSRAAEMKLPNWYLAAGALTQTVWNVVTDRDPELGIDDYDLIYFDDSDLSWEAEDAVIQAGKKIFADIPTEVEIRNQARVHLWYEKKFGKPCPQHRSSEASMTTWGTNTALIGVRLREDGEWDIFAPWGFSDMFRLTVRPNQMIMTEETYHKKVQRWIKLWPELTIMPWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLF1</accession>
    <name>X0BLF1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658463">
        <property type="protein sequence ID" value="EXK79703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLF1"/>
    <dbReference type="HOGENOM" id="CLU_139299_1_0_1"/>
    <dbReference type="OrthoDB" id="5015991at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="111" mass="13640" checksum="18D1797F8F9734D3" modified="2014-05-14" version="1">MCYFDQIRWACGYWRWGHFRQQCNKEYRMGETCGLKLVYETRTARDKCKLCQDTGKKQRRYDKMYRDVQRWQREGNRNATIERTCAEMQEVLGQIYRMGEEHDHRLQSLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLR7</accession>
    <name>X0BLR7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phenylacetyl-CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLR7"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_2_1"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF422">
        <property type="entry name" value="BCDNA.GH02901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="48"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="476"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="578" mass="63599" checksum="E8886EFCBEF6AB5E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM84</accession>
    <name>X0BM84_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Branched-chain-amino-acid aminotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979345">
        <property type="protein sequence ID" value="EXK79589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM84"/>
    <dbReference type="SMR" id="X0BM84"/>
    <dbReference type="eggNOG" id="KOG0975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020844_4_1_1"/>
    <dbReference type="OrthoDB" id="25921at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050571">
        <property type="entry name" value="Class-IV_PLP-Dep_Aminotrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42743">
        <property type="entry name" value="AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42743:SF11">
        <property type="entry name" value="AMINODEOXYCHORISMATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="36205" checksum="289EFADAE0423CEE" modified="2014-05-14" version="1">MATMQEIFKGFEERQARLVEDGLKNPLAHGAALIEGQITPLLDAKIPVLDQGFLHSDLTYDVPAVWDGNLFRFNDHLDRLERSCAKLRLKPPMSRSEIEQATINLISKSGIRDAYVQIIVTRGFRFVREPLPTSDTPENHFIYILVMPYIWVMPPQMQPVGGEAVVTRTVRRIPPGAIDPTIKNLQWGDLIRGLLEAQDRGSQYPFLTDGDGNITEGAGYNIIFVKDGALYTAKKGVLEGITRQSVFDVAEKAKILVYLDDVPASLAYVADEIFLCTTAGGIMPITKLDGESKGEVGPITKLIWDGYWAMHYDPRYTTKISYES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMM2</accession>
    <name>X0BMM2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_15321</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NRP synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658451">
        <property type="protein sequence ID" value="EXK80148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_60_6_1"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="CDD" id="cd19542">
        <property type="entry name" value="CT_NRPS-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="CDD" id="cd19534">
        <property type="entry name" value="E_NRPS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd19545">
        <property type="entry name" value="FUM14_C_NRPS-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000016">
        <property type="entry name" value="Nonribosomal peptide synthase Pes1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.30:FF:000002">
        <property type="entry name" value="Nonribosomal peptide synthase Pes1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.30:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthase Pes1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000015">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.30:FF:000003">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000014">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003417">
        <property type="entry name" value="PRK04813.1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45398">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45398:SF1">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="774"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="2312"/>
            <end position="2388"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="3401"/>
            <end position="3477"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="4941"/>
            <end position="5017"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="6032"/>
            <end position="6108"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="7076"/>
            <end position="7152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="7022"/>
            <end position="7049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK80148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="7623" mass="840893" checksum="D13AE9D5E5A6BB2F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BN98</accession>
    <name>X0BN98_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_15084</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Vacuole membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ATG22 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658446">
        <property type="protein sequence ID" value="EXK80378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BN98"/>
    <dbReference type="eggNOG" id="ENOG502QTJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017518_2_0_1"/>
    <dbReference type="OrthoDB" id="42657at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050495">
        <property type="entry name" value="ATG22/LtaA_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519:SF5">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK80378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="532" mass="59321" checksum="036359148620BE24" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNA5</accession>
    <name>X0BNA5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_15094</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658446">
        <property type="protein sequence ID" value="EXK80388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNA5"/>
    <dbReference type="eggNOG" id="ENOG502S0DZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035734_0_0_1"/>
    <dbReference type="OrthoDB" id="2140105at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022703">
        <property type="entry name" value="DUF3533"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053001">
        <property type="entry name" value="MNNG_permease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814:SF2">
        <property type="entry name" value="DUF3533 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12051">
        <property type="entry name" value="DUF3533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3533" evidence="3">
        <location>
            <begin position="51"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK80388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="442" mass="49237" checksum="01C2C8F00C890DB4" modified="2014-05-14" version="1">MTVDLEQQPSSPAPTLHGEPAVMEDTQRHGINSTIWHGRRGLVVKILTGIMVAILVVFLADLSYVFGSTFEVGNRVSGLKILVVDYDGGAVGESVANAYKNFQDKTFPTLEFRSADDYPETKDVKHGVCNADYWGAIYINKGSSDKLAAAYEGGSAAENYNPADSITYIYNSARYPTVASGYLVPNLQKVIGAARGSYYQSQQGRSALRSVNSSDPAAVEAYLNPIQGTADVIQPTNQGSRNLYNTINIVMAILGQFFYVLAMNGIYDKFGLHKNMRIRDLFIMRFINGMIFSALYALVVTGYIWAFREDWDVSGGQFALSWLTFWLFMDVNFQVLETLIGSYIPMALTPFFLLTWFMMNVGSVVFPFELTAGFYRIGYIFPAHSLWIILIQVWSGCGNSLHIGLPILFAWWVVGHVTAFFGIRKRCLDQLENLNTAEGKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNF8</accession>
    <name>X0BNF8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNF8"/>
    <dbReference type="HOGENOM" id="CLU_3191362_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="46" mass="4747" checksum="CA6C794A656DA069" modified="2014-05-14" version="1">MPVNAGPEYLSVMRGGPRGTQQSDINAPSQGAESLLVGHPISRGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNW4</accession>
    <name>X0BNW4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">6-methylsalicylate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_12242</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>6-methylsalicylate + H(+) = 3-methylphenol + CO2</text>
            <dbReference type="Rhea" id="RHEA:23112"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17231"/>
            <dbReference type="ChEBI" id="CHEBI:36658"/>
            <dbReference type="EC" id="4.1.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:23113"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.52" evidence="7"/>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNW4"/>
    <dbReference type="eggNOG" id="KOG4245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039329_2_1_1"/>
    <dbReference type="OrthoDB" id="2832284at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047596">
        <property type="term" value="F:6-methylsalicylate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF29">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="2"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK83546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="238" mass="26936" checksum="56581214F6B5585B" modified="2014-05-14" version="1">MNEYSASLRDANPMNGFFATVPSLQHTDLVLKELHYAFDTLKADGVTLFTSYATPQGYLGHPEYFPIWEELNRRKAVVFVHPINNVAAVYFDDRLPMPAFDWHYETGCIAIDMVLNRRLEQFPDVKIILSHAGGTLAALVQRATMIALPEYGDIMSAEDIVKQAKQFYFDAALSGSQEAFPMILSFAKPGHLLFGSDFPHAPEELSKGFTKFVDTFPLEDQNNRNIYYEAALKLFPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPG9</accession>
    <name>X0BPG9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxidase</fullName>
            <ecNumber evidence="5">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12067</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="5"/>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPG9"/>
    <dbReference type="eggNOG" id="KOG4157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004824_4_0_1"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF53">
        <property type="entry name" value="HEME PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006994438" description="Peroxidase" evidence="5">
        <location>
            <begin position="24"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="6">
        <location>
            <begin position="120"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK83731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="530" mass="57383" checksum="DD1F28F5E9F7A211" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPX8</accession>
    <name>X0BPX8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_14978</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979337">
        <property type="protein sequence ID" value="EXK80544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPX8"/>
    <dbReference type="eggNOG" id="ENOG502SJAK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031390_0_0_1"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="45"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK80544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="477" mass="53024" checksum="2DC7316ACE2C770C" modified="2014-05-14" version="1">MTHRNEVEAVLTKLKPLTNQLSPNDLITRDHDDYSRHTATFSANANCQPAVVLIPSCADSLAEVMRFLYKSDLDFHIRGRGFKSPSARDVIVSLLGFTDFDYDAEKKLATVGVGMTWAEAAERMKELDPEYSLTYARTPSVGVGGSILHGGFSWMSSEFGMISDPINFIDAEVVKYDGSIVMASTEPELMWALRGSGGGFGVMTKVVLRAHQYPTRIWSGMILIPKDHLQELASKIHDFISKPQHPKLNFLTFVVQQHLLPAVLETDQLSAFTGDVIVLQVYDACGENHGREAFRWALEMPGVIDKTRVGDIKSVLDMQMNIGGMNRSMAELHVLAMGLADASEDTVLRALTWPDKIAAIDKDIHQLTMIVPEFLVFSPPIGGVAEVAWHRPTNLKHYILAAVGSPSHGTVLQNEMARQIIQHAPKDIVGSQEYNVLPTSSDEMVDTKLAYGAHWNKLIKLRRKYDPDLRFKTLINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPY5</accession>
    <name>X0BPY5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-dehydrosphinganine reductase</fullName>
            <ecNumber evidence="9">1.1.1.102</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_11683</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>sphinganine + NADP(+) = 3-oxosphinganine + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22640"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57817"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.102"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:22642"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.1.1.102" evidence="9"/>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPY5"/>
    <dbReference type="eggNOG" id="KOG1210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_3_0_1"/>
    <dbReference type="OrthoDB" id="10267115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047560">
        <property type="term" value="F:3-dehydrosphinganine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006666">
        <property type="term" value="P:3-keto-sphinganine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08939">
        <property type="entry name" value="KDSR-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045022">
        <property type="entry name" value="KDSR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550:SF3">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK84200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="347" mass="37877" checksum="49E3C9377C71D52C" modified="2014-05-14" version="1">MDLSPTTLVTYIAISAVTLVVGWFIMGFFGGNKFPVEGKTVLITGASEGMGLSAATQLSAKGANIVLVSRSASKLEAALFTVKAAAKNPQTQRFHYIAADVSAESYAKPLLEEVISWNNGQAPDIVWTIAGFSFPELFVDMEMKSMRQHMDVNFWGTAEMAHAAMREWLAVDKPVEKEPKHLIMTGSVCACYSPPGYTPYTPSKYAMRGLAECIQQEVMLYPQNVQVHLVLPGTILSPGNVRENEHKPEITKTIEKDDPKQTPDEVAAAAIKGLEAGQHHITVNFLGSLIKWASFGGTPKNSFVDVLGALLATIVWIFVRPILDHQIKSHAKKYGHPSLYNKKSSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSH6</accession>
    <name>X0BSH6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_13747</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSH6"/>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="OrthoDB" id="6509908at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="239"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK81878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="424" mass="45867" checksum="01399BB1A8D41C70" modified="2014-05-14" version="1">MDTTKDRTDDNPLVESSFSVDDTSPKPIPNGGLLAWLQVAGSFCLYFCTWGLIASFGSFQTIYERDQLSTHTPFQISVIGSLQTFLMVFSGFIVGPIYDSGYFRHLLAVGSTFIVTGTVLQSLSQKYWQYLLTQGLMIGIGAGCLSILSVAITSLWFTTKLPLVNGLAACGSGLGGVLLPIMIRELNAQTSLPWATRAMALLLLVLLLFSNLVLRPGLNPNAPSQRRQLLDNTAFTDWPYVLFVAGCFSVFLGMYTPFVYVQSYALDNNIASDLSGNMLAILNSSSIFGRILPAFLAQILGPMNTIISAAVLLATTSLCLISATTTPRLLVTVISQGFFTGSFFALQPTIFVRLTSDPRRIGTRFGMAFSAMSVALLFGPPVGGALRRSMGYTAAWVWAGLTIFIGGILILCSRLLKDKKSLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSN2</accession>
    <name>X0BSN2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_10809</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_0_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901336">
        <property type="term" value="P:lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030639">
        <property type="term" value="P:polyketide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05274">
        <property type="entry name" value="KR_FAS_SDR_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="57"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="12">
        <location>
            <begin position="994"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="2329"/>
            <end position="2406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="994"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1155"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="1026"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK85155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="2410" mass="260338" checksum="0EEA651C3DD5DA86" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSV8</accession>
    <name>X0BSV8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658425">
        <property type="protein sequence ID" value="EXK81574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSV8"/>
    <dbReference type="eggNOG" id="ENOG502RZ2M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028123_3_1_1"/>
    <dbReference type="OrthoDB" id="5977668at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3110.10">
        <property type="entry name" value="protoporphyrinogen ix oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.20">
        <property type="entry name" value="Protoporphyrinogen oxidase, mitochondrial, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF42">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="480" mass="53011" checksum="603385495220E409" modified="2014-05-14" version="1">MNDKHTKSRVAIIGTGLAGLSSAYLIKGDRYRVTLFEQGDRISFDSASVTIKNEKYDDAERIDLPMRASADGYYHNLMRMYQHLQIPLHPIKFLFVFAKAATSADGTVPVKGSDNETYFIHASNLHQTPPPWPGNRGVIAHFIEIVFLIVCQFWFTIACFLVAPLKTTSSGYSETVAEYFDRIRLPRRYTSRYLLPLLSGVATCTHEELLQFPASDIVNYKKLSHGKQHYAVCGGVSQVQAKLTEGLEDVNLNSRVIEAVPQVDGTVLVRWQSTVDASGRIHEQVFDRVVLSVSPDVAGRIFKPLGSTLAKLPTRQVESSVLKPEKAGISVVDTDDANSRQSIACMHHSKDTSAAQVLTLRTMFTDVGSPRTEALHAMPSGVVVSTCPLREEAQPEAIKKAKFTRTLRNTKGQALVQKLLGDSGSKKSEDDEAITWVNGQDNVWIAGAWCWDGMVLLEGCVVSAIRVAQDFGVAIPWEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVJ9</accession>
    <name>X0BVJ9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVJ9"/>
    <dbReference type="HOGENOM" id="CLU_2671184_0_0_1"/>
    <dbReference type="OrthoDB" id="415590at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="75" mass="8126" checksum="FCEF6311F9B43E6B" modified="2014-05-14" version="1">MVEDHTREKRCLFTPGARATWRKAYFINAKQLGGGTRPDMVVSQMGIGKDVIETVLATDGKAGIDFCINAAPATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX08</accession>
    <name>X0BX08_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09709</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX08"/>
    <dbReference type="eggNOG" id="ENOG502T474">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079938_0_0_1"/>
    <dbReference type="OrthoDB" id="3559235at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="310" mass="34531" checksum="4FE18C4D479670EC" modified="2014-05-14" version="1">MIDPIGAVAAATASIDQSLKLIRRVSTAIEIHKNGRKDLEFIFEDLSSIAQVIELVQTIEEIRTKGVLKALANMLKHAEKLDDHVQQVKKKSNTGSSFRRAAHHFMTGPEDLEHTNRVVKELTSLKTTLILHIQVAHVGLVVQNDQDKRANPGCTHMLDSSVLHEVNQVVEQRLGKGQGLKIAEVLRGKSADDDGMIRLSQEEYECLVFHSLDDSQSNQELGTIRVANNQTFDQALQINGCISDDWMEFAQNLTIEDNEARNQSIQVNVPTSRQDFAALLAVRNKTLEMMPSSGWAPAPLMPKQTIRSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYA0</accession>
    <name>X0BYA0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_12195</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYA0"/>
    <dbReference type="HOGENOM" id="CLU_024397_0_0_1"/>
    <dbReference type="OrthoDB" id="103819at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="591"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="603"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK83494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="708" mass="79651" checksum="4B3D158428B7C958" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYX0</accession>
    <name>X0BYX0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYX0"/>
    <dbReference type="HOGENOM" id="CLU_1602799_0_0_1"/>
    <dbReference type="OrthoDB" id="5100126at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="166" mass="18947" checksum="5B59B03CB52BAC30" modified="2014-05-14" version="1">MQTVNPTLLAQQASYAPSYTGRPSNPITASSYNRQTQNNTPSPSPYSSMGRQETWMGSVGFTDRFTRDSMGYGRATPDVTLTYESEPLEPLFGRAQPLPQLPPPDIQQPTARSRQRHRGDKTWSRKQLHSRYIEVPRKVIHNGKENIVTKTVYFNRSYGGYWHSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C193</accession>
    <name>X0C193_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_11323</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C193"/>
    <dbReference type="eggNOG" id="KOG3923">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034311_3_0_1"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF11">
        <property type="entry name" value="D-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK84534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="332" mass="37099" checksum="EA40CCF77C8F19E5" modified="2014-05-14" version="1">MEVGIIGSGIIGLTSALALVEAGYSVTIVARDLPGNDSSQQWASPWAGAGILPHPDYKGHDLQTESFKFYWALAHRDPTSGVQVVDVTEYYDDRDDDSTIWYKRMAPKYRRLPSKDLPANAKIGFKYQSMTVNPAVFLPWIKAVLDKKGVRFIRAEVKTIEEARSILQIKRIVNASGLGAFHLANDNKVVAVRGQTMLVESDSHEMVMFQGSHYTYQIPRMYSGGVIVGGVSQPGNMDQKVDPEVRSDILRRMKLVMNDQYQGVDLDKHVMKDLVGFRPSREGGYRLEREDDVIHAYGFNTLGYTYSYGVALKVRDLVTSATIEEAAVRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1H9</accession>
    <name>X0C1H9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979468">
        <property type="protein sequence ID" value="EXK76642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1H9"/>
    <dbReference type="HOGENOM" id="CLU_000799_0_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="692"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="737" mass="79574" checksum="CDA8C00CE78E279A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1N3</accession>
    <name>X0C1N3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_18581</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658692">
        <property type="protein sequence ID" value="EXK76682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1N3"/>
    <dbReference type="HOGENOM" id="CLU_028200_0_4_1"/>
    <dbReference type="OrthoDB" id="3648173at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="34"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="348"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="353"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK76682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="409" mass="45672" checksum="4636C1CDEC3FC8BD" modified="2014-05-14" version="1">MDSRSMSADSSSRSVEIRAILITFSILSTITVALRIYVRYKVLRSLGWDDRVMAAAQLLTIGSAVAIGLENNYGLGHHTWEQSKENYVAYMKAFYTSVIVYNVAMCLVKIGILHQYRRVFVIPILQALTFYGLVIMVAWTITIAFLNTLICVPVAKFWNSTMPGHCTDPLTVWYVMAGFNLVTDIIVFCMPLPVIGSLNLPRRQKIMLLAIFSIGFLTCAISIYRIRTLKTAASTKDPNWDNVDAAIWSFLEVTLAIITSCLPTLRPLFSKLMPKLFASSFGRSNRPSDYGYTPTHSSQNLRSMPRLRTEDLSRDSMDATTTLRKDEVPLSSISHRCYCQGYPGVSVSIKPEQGQNQSDETQSPLEPSSPIHGGIKATTVVSQEVVVERVADDEWSHGRPSDSDANMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1X2</accession>
    <name>X0C1X2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1X2"/>
    <dbReference type="eggNOG" id="ENOG502SHVK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038717_2_0_1"/>
    <dbReference type="OrthoDB" id="72269at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936715" evidence="2">
        <location>
            <begin position="21"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="395" mass="43722" checksum="E5864B674895D66E" modified="2014-05-14" version="1">MAPKSIVCLILSCALLGGYASMGTSYRHGFFDAVRDCITNAKSPDGSSLCPLDMSDSISRKLTGYQAVDEPVMLLLEFFAQGLKKHPESKDMDLEALLAFVYLAAQFCGAWYLIALEGLRFGNRGTILSWTGSFGIVFQSVTITIIAPIYLTLQLLLSPTIPQQAYLLADPCDLSLLPISTAISYIVPTIGLCLPLIFDVSREAKFIAVALWQPFPLYQTAIQRVSRLVCWSRRGKANNTAHIDPRACRKAMNRAYRFITTVAVGVHLAVFGTILASSMDLTDNVSGRHILALTSLTNPPTLALLSPPVSAMQSREIVVSFLRWDVYCTCLAMAIWTGYQLYSAQRAPSRVVICFNTIWWTILGGPIYPALRHLWERDAMVLDRMELFSSSLKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2P1</accession>
    <name>X0C2P1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2P1"/>
    <dbReference type="eggNOG" id="ENOG502RN7X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067396_0_0_1"/>
    <dbReference type="OrthoDB" id="5207704at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="344" mass="38417" checksum="DCD21BC6A5FB3F83" modified="2014-05-14" version="1">MDVLLNSSGDLPAAKHFHINPPSTLKTRAQISRNHFVRATAKRQSQHKGANLCRDTGFPCTTSSFGETHCLRCGQQDSTNTNGGARRPQLEKILHYEISTGNLQRANPRWTHVHRNRMARKHDHSSLGGSSDEVEGRDLANSRISLPVDRFRLVRRPTLEREEAFRDASTARGNVYLGRKMPMTEDDEVAELYRMGLLYDDEQIRGEGFNLDSIKHEEPTYSIRPAKQSRKKRAQSFSFNQPLHLDLSFTDLGGSQALAQILSSSDDTAPSATPTRSFAPLRVIYELDGSNPSFDVDTSQPPDLISDYDCLSDSELDDLPSQREFLDSAATPGSETWVVLGDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3M3</accession>
    <name>X0C3M3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Solute carrier family 40 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_10206</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in iron transport and iron homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3M3"/>
    <dbReference type="eggNOG" id="KOG2601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020370_5_0_1"/>
    <dbReference type="OrthoDB" id="648861at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17480">
        <property type="entry name" value="MFS_SLC40A1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009716">
        <property type="entry name" value="Ferroportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660:SF57">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06963">
        <property type="entry name" value="FPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK85763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="528" mass="58269" checksum="3C28F541130E889E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0C441</accession>
    <name>X0C441_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_10360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C441"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF62">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="65"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK85564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="492" mass="54677" checksum="82A2855186A6AF60" modified="2014-05-14" version="1">MAVLSEPQMSTPPKDVKPDAGFDAVHDEKVIEQNGVDNHRGDYSGAATKTDPAEIALVRKLDRMIMPILWAMYFLNYLDRNALPQARLNSLEKDLNLKGVQYNTAISILFVGYLLMQIPSNMFMTRTRPSIYLSCCMIGWAAVSACTATVKNYSGLIACRFFLGFVEAPFYPGALYLLSIYYTRKELATRISLLYTGQVVSTGCSGLIAAATFSTLDQAKGIAGWQWLFIIEGSVTALVAVFGFFLLPDDPSETRWLTPEERELCIKRISRDTVGQQVRGTTWEGLKQACKDPRTWLFCLMQNLHISACSFNNFFPTIVRAMGFKSTTSLLLTAPPYFVSGILGIPFAWSSGHFNERTWHITAGLSLAVVGFVMSCATVNVAVRYTATFLYATGAYSVGSVILGWVSNTLSQTPEKKSVAYALVNVTANLAYIYCAYLWPSSDGPDYLMGFSTMVAFAATSIMCAWAMRFWLKRLNRKILESENENVAFYAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4E5</accession>
    <name>X0C4E5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4E5"/>
    <dbReference type="eggNOG" id="KOG1143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006343_0_0_1"/>
    <dbReference type="OrthoDB" id="5342685at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF30">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="2">
        <location>
            <begin position="293"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="877" mass="95008" checksum="83A19FEBDF85DCF8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4W1</accession>
    <name>X0C4W1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09912</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4W1"/>
    <dbReference type="HOGENOM" id="CLU_2015343_0_0_1"/>
    <dbReference type="OrthoDB" id="2113814at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071439">
        <property type="term" value="C:clathrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292:SF1">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="146" mass="16686" checksum="68D892AB3F848EB9" modified="2014-05-14" version="1">MGSRRCLVLKHGYSPASGSTALLMVAYLFPFLSDAFLKLFAKIYIDSNNKPEKLLNENDHYDTIGKYCEKRDLNFGSVPSPRSILTPTITRRERPLRHTHYRKVLKFLKENDQYDTLTIGKCCEERDPNLACVASSKGQNDLELVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-11-27" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5L8</accession>
    <name>X0C5L8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5L8"/>
    <dbReference type="eggNOG" id="ENOG502SHNX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2867710_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="64" mass="7338" checksum="6C377B01A902CB26" modified="2014-05-14" version="1">MWIVDGDSEEAVTRSTPGEIHSWIWGSDLVILPGVSHFAFMQDPETFNVMVERFLEMPRFPGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7F9</accession>
    <name>X0C7F9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_09553</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7F9"/>
    <dbReference type="eggNOG" id="ENOG502SHAW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014025_2_0_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF6">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="91"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK86729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="704" mass="78405" checksum="97B7FF4360E1DA45" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7I8</accession>
    <name>X0C7I8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_07186</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7I8"/>
    <dbReference type="eggNOG" id="KOG0024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_3_1"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08282">
        <property type="entry name" value="PFDH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF3">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="9">
        <location>
            <begin position="30"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="8">
        <location>
            <begin position="190"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK90390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="386" mass="41447" checksum="220C8FFA7B4EEB4D" modified="2014-05-14" version="1">MTTQTMKAVNYQGPYKVKVQDIELPKLEHPDDVIVKVTTAAICGSDLHMYEGRTAAEPGITFGHENMGIVEQLGEGVTLLKKGDRVVMPFNVADGRCRNCEEGRTAFCTGVNPGFAGGAYGYVAMGPYRGGQAQYIRVPYADFNALKLPAGKEHEADFILLADIFPTGWHGVEISGFRSGESVAVFGAGPVGLMAAYSAVLRGASRVFVVDRVPERLQAAEKIGCTPIDFSKGDAVDMIIKANDGEEVDRSVDAVGYQAVSKSGDTEQPNIVLENMIKVTRACGGLGIPGLYVPSDPGASDEASAKGMISLSFGKLFEKGLTIGTGQCNVKSYNRYLRDLIISGRAKPSFVVSHEINIEEAEVAYEKFDKRIDGYTKVLIHPNGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8Q8</accession>
    <name>X0C8Q8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_16257</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979351">
        <property type="protein sequence ID" value="EXK79092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8Q8"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF49">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="95"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK79092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="597" mass="66403" checksum="689CEB8EE585991E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C981</accession>
    <name>X0C981_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C981"/>
    <dbReference type="HOGENOM" id="CLU_631672_0_0_1"/>
    <dbReference type="OrthoDB" id="4867305at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="415" mass="46913" checksum="E430A274F36FC544" modified="2014-05-14" version="1">MLVRGHNALRSSRALFGLPSLVRYRGKIKEEPEPEQKEKQKPKERQTTRPWPSGLQELGAKSARPIPADPSSTFTMVNIPNASTAYERWPTLKNFKPALQPRTCGTIRPGAGPGGGATVDTYMELSCLPYLYNDLGVMIFEGPHCVQDRDWTTGKAYYEVNYSKWNVYRIKLDPGKHVETSSQNGRRKSSITPDGLYDLSNIALEKWKADGIGGPVPVETLPGSMKMYILNHTGGPGLANDTINGSYLPQLHVYVATGIRGNTIYMCIEFHTVGTRRLVGVTYLKLRPTFDLSPAKYMAEEPLQRVDGNTNFDQKFATIEEKKKAGREADPYSEKQAFQPPPPHARSIESPWEFYEKLVPSNTRRNSDIFKAAMFELYKLEMRLWSQRKRAMKKEKEAKATVEGHSSYKRKVSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9D5</accession>
    <name>X0C9D5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9D5"/>
    <dbReference type="eggNOG" id="ENOG502SM97">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023464_1_0_1"/>
    <dbReference type="OrthoDB" id="3728558at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="1">
        <location>
            <begin position="284"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="502" mass="58654" checksum="D75C67D9BDF2A1A9" modified="2014-05-14" version="1">MANQTTQQHRMRLRSSGCLRWSYLPQEIRRNILNTIVDQRNPRWSALASVSKEWQSVIGTRNMAKLNLRPSCLEDFEQAVVRQRDLVRHIYLNVELTEYKCTLCKNKFAITIAEKNNRLMSKAVTKLLTILSTWNTTGPLTLELNASSASDSKHWFKNFRFNDEHDAPYSRDSVIPMEGMHSDWHDPKHGWENGVRVKPPPISANKRLFGLINLNGPPYSILNVNAVTRFMIRRQFRHRLGPREFASLLSKFSRLTDLVYEPWPQKYTDSYRYPWDPALIGMHLPRTLKRVILFQDFKQYLTENTRQDLDHFYYAILPIHWSKFNLPGNAKSIAQTSLRLNELAVSFFIDAVNFFKACEEEWTWDYLQSLSLTSSLLLQNIKEQKGRIDSLLITAAKFLLRMPNLTTMALWSGGTGKACAFMYTRTKQYAHVTWRGTWDLEISRQVLEAWEGVAKLHSVELRVRHERLQEIIRSHGDAIFHLNLPCQVIEPTSLWQIRMEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9R1</accession>
    <name>X0C9R1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TECPR1-like DysF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_06980</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9R1"/>
    <dbReference type="eggNOG" id="ENOG502QQTF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024267_1_0_1"/>
    <dbReference type="OrthoDB" id="74314at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052816">
        <property type="entry name" value="Peroxisomal_Membrane_PEX28-32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28304">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28304:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="TECPR1-like DysF" evidence="7">
        <location>
            <begin position="103"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="441"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK90856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="491" mass="55951" checksum="25DC3DE14E8DDD4A" modified="2014-05-14" version="1">MDDFTAEMFASGRNFDSPESSSQRPNNDHNDDNDKQPEPKAESSSQKTGLRGGFAAIRQKASLQDRLVEKLLQQVIPTDSDDQTEVHFAGDEQSATHTERPNFNITTMSYNFRRFNARIGVVFKFQARVERILSWKRASHTLSLLAVYSFVCLDPYLLFVLPVAILLFGVFIPAFLARHPAPPKGTLSSEQNVGYSPQGPPLAPAATVKPVKELSKDFFRNMRDLQNCMDDFSRGHDQVVALLVPVTNFSDEALSSALFLFLTAGGIFMTIAAQILPWRFIFLLGGWVIVGMGHPHVARLIAAAHRDRLQPQEAKARSWLDNWISSDVILDSSPETREVEIFELQRKTSGGGEWEPWLFSPSPYDPLSQPRIAGERPRGTRFFEDVMPPEAWEWSEKKWALDLWSREWVEERIITGVEVETEGERWVYDIWDERDERTGVVDVPINDKGKQKATPKPSWEENEDGSGRRGDWRRRRWVRLVKRKAAPVQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAE5</accession>
    <name>X0CAE5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAE5"/>
    <dbReference type="eggNOG" id="KOG3407">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091076_0_0_1"/>
    <dbReference type="OrthoDB" id="10261348at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013169">
        <property type="entry name" value="mRNA_splic_Cwf18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08315">
        <property type="entry name" value="cwf18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="208" mass="23101" checksum="696219EB3416B56D" modified="2014-05-14" version="1">MSSSHASLSAASDDRKARLAKLKNLKRKQPGDEIVAPESERAQSPPVEPDVSRLHVSGRNYDPETRGPKLGFEQDPTLNLDKPTLEEQAAEVEAEVKQKAAEEAQDDQGVDLFKLQPKKPNWDLKRELDRKMEVLNVRTDNAIARLVRDRITGAQKAAAKRDAVEDAQGTGEATGMDGVALVEGLRVREKEEEEEERREREEDAALGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCB4</accession>
    <name>X0CCB4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCB4"/>
    <dbReference type="HOGENOM" id="CLU_612561_0_0_1"/>
    <dbReference type="OrthoDB" id="2520703at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="52331" checksum="3A2095BD91BD527D" modified="2014-05-14" version="1">MSEPEPTALWLPDEVLFNILSTLQGSDDPDAISTKEANITLFNTCLASRRLESLAQRVLYRCIDARSSKCLLTLGQNPHLCRLVRELYCPYDEKVVNALLHPHFRNYIWLPSSWSASFPNWLESEHGRQEYYGQATAFWVQRLPNLNRLTISLSYDMKALTEMVQKSLNGQPRRFPRLTRIDFKLCPSGIPPCIQPSLILFQLPFLKTVTIHDMPFFAKSSSGDLDMPRNACKRLERLDADFAWITPGSLRNLLSVCESLRFLDIKVRTMLSTTCDPFNYRLGDWIQHCHALESLDLQIKASRRWTDGLTGGREVQEQTWAANNIGSLQNLTRLKRFSLSVELRHLTVPGPSVPPPSPSKLDFELMLPTSIEQFEIRKIGIPDYKAFVRNMRELLQSKRLTNLFQVSVAAHLKPHHVTHPSWEVQLHGPGQFDKVLQLVHKDRKGTIQSSRYDQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE80</accession>
    <name>X0CE80_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_07851</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Binds one iron-sulfur cluster per dimer. The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE80"/>
    <dbReference type="eggNOG" id="KOG0911">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026126_12_0_1"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02984">
        <property type="entry name" value="TRX_PICOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000012">
        <property type="entry name" value="Monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000092">
        <property type="entry name" value="Monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF73">
        <property type="entry name" value="GLUTAREDOXIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00055846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK89129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="252" mass="27379" checksum="D8D8DDA9B75A2FEF" modified="2014-05-14" version="1">MSTITEITSIPEWEQLLSSVPSTTLVVASFHAPWAAPCAQMATVLSTLASEYPVTEPPTTKWVSINAEDLSDLSETYDVTAVPFLVLLRNGQVVETVSGSSAVKVRTAIETQAKQSGQNAEASAQNGIDTNDAEAEEQDPEKKKEELFKRLGDLVKAAPVMLFMKGTPSSPQCGFSRQLVGLLRDNSVKYGFFNILADDEVRQGLKEFADWPTYPQLWIDGELVGGLDIVKEEMANDAEFLTKYSVSAPAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEM9</accession>
    <name>X0CEM9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium binding protein 39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mo25 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEM9"/>
    <dbReference type="eggNOG" id="KOG1566">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="609103at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000257">
        <property type="entry name" value="Conidiophore development protein hymA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="369" mass="42272" checksum="1E9CA7497CF1B6C8" modified="2014-05-14" version="1">MSFLFGRARTRTVADLPKQAREHVLKLEGPQGPSKAEELARVLSQMKTILQGTPEADTSPEQILQLVTGLIDEDLLHLLAVNLFRLPFESRKDTQVIFSYVFRFRPATAAPKSDPLALSYVVCNRPQVLVELCRGYDHKESATPAGSVLRELLKNEAAAAIILYDDGDEPGSSSKGLNAIDRDRPQSGRGVFWRFFDWVDKSSFEVAADAFTTFRELLTRHKDLVPRYLNANFELFFDKYNNILVQSNSYVTKRQSIKLLGEILLDRSNYNVMTAYVDRGEHLKICMNLLRDDRKMVQYEGFHVFKVFVANPHKSIAVQKILLMNRDKLLTFLSHFLEDRTDDEQFIDEREFLIKQIRGMPSVPVAPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFF1</accession>
    <name>X0CFF1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TTK protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_07425</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFF1"/>
    <dbReference type="eggNOG" id="KOG0596">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_2_10_1"/>
    <dbReference type="OrthoDB" id="20524at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033316">
        <property type="term" value="P:meiotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098813">
        <property type="term" value="P:nuclear chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14131">
        <property type="entry name" value="PKc_Mps1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000377">
        <property type="entry name" value="Checkpoint protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000131">
        <property type="entry name" value="Dual specificity protein kinase TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027084">
        <property type="entry name" value="Mps1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974:SF21">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974">
        <property type="entry name" value="MIXED LINEAGE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="542"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="25"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="420"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="570"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK89968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="885" mass="98268" checksum="24726596131FC93D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGK3</accession>
    <name>X0CGK3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TPR domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGK3"/>
    <dbReference type="eggNOG" id="ENOG502QU74">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011527_0_1_1"/>
    <dbReference type="OrthoDB" id="414774at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45588">
        <property type="entry name" value="TPR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45588:SF1">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="571" mass="64554" checksum="C1763A00E175AFD3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIU5</accession>
    <name>X0CIU5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIU5"/>
    <dbReference type="HOGENOM" id="CLU_3160028_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="48" mass="5632" checksum="A939D64C897AD751" modified="2014-05-14" version="1">MSLRENEDQSDKKLGELWVIASFNSLWNVHRAKKSSRASVRLIVVIRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CL99</accession>
    <name>X0CL99_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Urea active transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12342</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CL99"/>
    <dbReference type="eggNOG" id="KOG2348">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010778_2_1_1"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015204">
        <property type="term" value="F:urea transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11476">
        <property type="entry name" value="SLC5sbd_DUR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154:SF1">
        <property type="entry name" value="ACTIVE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="615"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="543"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="555"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK83322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="661" mass="71611" checksum="5A82667BA3433BD9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM40</accession>
    <name>X0CM40_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CHK kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CM40"/>
    <dbReference type="eggNOG" id="ENOG502S600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061751_1_0_1"/>
    <dbReference type="OrthoDB" id="191037at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052961">
        <property type="entry name" value="Oxido-Kinase-like_Enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23020:SF41">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23020">
        <property type="entry name" value="UNCHARACTERIZED NUCLEAR HORMONE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="2">
        <location>
            <begin position="132"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="372" mass="41774" checksum="CB23FF6F79D05DA7" modified="2014-05-14" version="1">MFNSLVTGSQAPRGNFDSEKPLPLTPDEVTSEWLSEALGVAVKDFKISSVIHGTSSKVFVDLIFGDGVETEIPSRVVLKGGFNPVIRETVPQMLPTYRREAEFYYHVAPQTTMLLPKIWFAGTDTVNGQGIFIMSDVSSEATFGTPLEPWVPERVGEALKQLASLHAKTWNTKEEEYPWLFGKDGSKLENPVRNIILALLEPAPWGARFDEKVRPPVAKELLDPDRIRKAFQALWKHADADQKYYSLIHGDDHVGNTLIANDGTPGFIDWQGLQYGPSVLDLAYFLTGALTVEDRRKHEASLIDTYLEALHKEGGPKLTREDLWDDYRRYSMQGFLWAMTPQTMQPDEVVFAMAERYSACIVDHGTLELLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM60</accession>
    <name>X0CM60_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05917</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CM60"/>
    <dbReference type="eggNOG" id="ENOG502SJ8Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004804_0_1_1"/>
    <dbReference type="OrthoDB" id="5392779at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47840:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47840">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK91914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="668" mass="74461" checksum="F17FBD294286005E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM89</accession>
    <name>X0CM89_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acetoacetate decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CM89"/>
    <dbReference type="eggNOG" id="ENOG502S5U3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050866_1_1_1"/>
    <dbReference type="OrthoDB" id="9970474at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.400.10">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40518">
        <property type="entry name" value="ACETOACETATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40518:SF1">
        <property type="entry name" value="ACETOACETATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="32568" checksum="FE2AA6704CD2813C" modified="2014-05-14" version="1">MADLHIPSVPPPWTLKGDIYAFIFWTSPSQAKEGLPAMAYSPLEGQSDFAKDQKALGGLSMLQLIRYTDSPVGPYDELILAPGTFGYEKEDENGRRLKGKGVKITRIYVSHKHTCYNGRKNWNVPKHLAKFDWTDNSNGSITAKVYPHDTLPTDSASSESASPDHTPFFQATFKPIRYAPSFPFRTSWINYLGFDTTLVFPPLPEGAGSQGELPGTDQWCSVVPQQSTSKCMLGWFDVEQHRDEEGKLTGEFENFWLGWSKWQIGIKMENSVIEFDHPETWEPPRTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMH9</accession>
    <name>X0CMH9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMH9"/>
    <dbReference type="eggNOG" id="ENOG502RK20">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_539717_0_0_1"/>
    <dbReference type="OrthoDB" id="4636359at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="556" mass="63009" checksum="BBDDD4E794C3DE1C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ53</accession>
    <name>X0CQ53_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_05225</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ53"/>
    <dbReference type="eggNOG" id="ENOG502RSQP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008206_1_0_1"/>
    <dbReference type="OrthoDB" id="5354458at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056687">
        <property type="entry name" value="DUF7785"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057199">
        <property type="entry name" value="DUF7877"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25009">
        <property type="entry name" value="DUF7785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25289">
        <property type="entry name" value="DUF7877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7877" evidence="4">
        <location>
            <begin position="65"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7785" evidence="3">
        <location>
            <begin position="450"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="569"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="739"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="811"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="477"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="621"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="739"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="833"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="862"/>
            <end position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK92984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="886" mass="97387" checksum="A4FE8418B26FC710" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRX7</accession>
    <name>X0CRX7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRX7"/>
    <dbReference type="HOGENOM" id="CLU_2979127_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="67" mass="7215" checksum="29BA8DB7D8101D2E" modified="2014-05-14" version="1">MNTESISMGNIKGAISDPRGSHGSCKSLMDRSSAPQRPEKIVAPCPSVFPDLLLRKRGAEHHDELTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSV0</accession>
    <name>X0CSV0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chromatin assembly factor 1 subunit rlf2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02475</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSV0"/>
    <dbReference type="eggNOG" id="KOG4364">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013392_3_0_1"/>
    <dbReference type="OrthoDB" id="79480at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033186">
        <property type="term" value="C:CAF-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048800">
        <property type="entry name" value="Cac1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022043">
        <property type="entry name" value="CAF1A_DD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272:SF0">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21796">
        <property type="entry name" value="Cac1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12253">
        <property type="entry name" value="CAF1A_dimeriz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromatin assembly factor 1 subunit A dimerization" evidence="6">
        <location>
            <begin position="358"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Chromatin assembly factor 1 subunit Cac1-like C-terminal" evidence="7">
        <location>
            <begin position="558"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="406"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="116"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK97196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="622" mass="69941" checksum="BE68D38E1EDF89D8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSZ1</accession>
    <name>X0CSZ1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK93989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSZ1"/>
    <dbReference type="HOGENOM" id="CLU_2654602_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="76" mass="8643" checksum="EC063285EAF98FDE" modified="2014-05-14" version="1">MVVSKLQRLCQLLHVGRHDAIRRQARPVIGLQGMKNGWKMSRSQWLCGLILHVHGRGVPRGPSSWDFINAVKFRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUD5</accession>
    <name>X0CUD5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_10144</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_0_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901336">
        <property type="term" value="P:lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030639">
        <property type="term" value="P:polyketide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000019">
        <property type="entry name" value="Polyketide synthase type I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23297">
        <property type="entry name" value="ACP_SdgA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="13">
        <location>
            <begin position="31"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="14">
        <location>
            <begin position="953"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="12">
        <location>
            <begin position="2483"/>
            <end position="2560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="10">
        <location>
            <begin position="953"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="10">
        <location>
            <begin position="1116"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="10">
        <location>
            <position position="985"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="10">
        <location>
            <position position="1183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK86097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2576" mass="281283" checksum="AC09CBF0642EFF27" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUF7</accession>
    <name>X0CUF7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUF7"/>
    <dbReference type="HOGENOM" id="CLU_2291795_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="101" mass="11478" checksum="4BD25720BB60663E" modified="2014-05-14" version="1">MRFAKLWEARPTALVDDTCCNLTQATCWPIPHTHDANDQVFTARDAIAAQTHPHYLFAYVLTPHTKRNSGCGFSADVCLWNDLKLRMYKTPPPKQTFIAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUI6</accession>
    <name>X0CUI6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">HAL protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_01125</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUI6"/>
    <dbReference type="eggNOG" id="KOG0590">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_33_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF0">
        <property type="entry name" value="CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="378"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="287"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="718"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="158"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK98115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="739" mass="81447" checksum="C70D1D7278AA5BD8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVD6</accession>
    <name>X0CVD6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01131</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502QWE7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001023_0_0_1"/>
    <dbReference type="OrthoDB" id="2149224at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032065">
        <property type="term" value="P:maintenance of protein location in cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13365">
        <property type="entry name" value="PH_PLC_plant-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF1">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="1586"/>
            <end position="1697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="454"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1291"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1423"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1473"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1725"/>
            <end position="1784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1855"/>
            <end position="1886"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="208"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="512"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="604"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="625"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="656"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1296"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1440"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1473"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1504"/>
            <end position="1517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1542"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1740"/>
            <end position="1752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1761"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1855"/>
            <end position="1868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1874"/>
            <end position="1886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK98121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1886" mass="206159" checksum="483024F2C61725DA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CVQ3</accession>
    <name>X0CVQ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxalate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_09830</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CVQ3"/>
    <dbReference type="eggNOG" id="ENOG502QQ0P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030515_1_1_1"/>
    <dbReference type="OrthoDB" id="10263073at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033609">
        <property type="term" value="P:oxalate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20305">
        <property type="entry name" value="cupin_OxDC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20304">
        <property type="entry name" value="cupin_OxDC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017774">
        <property type="entry name" value="Bicupin_oxalate_deCO2ase/Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051610">
        <property type="entry name" value="GPI/OXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03404">
        <property type="entry name" value="bicupin_oxalic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848">
        <property type="entry name" value="OXALATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848:SF9">
        <property type="entry name" value="SLL1358 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937429" evidence="4">
        <location>
            <begin position="19"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="5">
        <location>
            <begin position="114"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="5">
        <location>
            <begin position="293"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK86562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="465" mass="52326" checksum="4BD6CE58CAF2DA6B" modified="2014-05-14" version="1">MHLPHLAYLAALLDICAGVPVEDSPRQRLLKGLGLPPNYRGVTGGKKVPFTPGHRDPIDKPVDSVGDELDPLPWRNGLGASVLGPWNEARSRQNPDLVRPPSTDHGNLANMRWSFADSHIRIEEGGWTRQTTIRELPTSVELAGVNMRLGEGVYRELHWHQEAEWAYVLDGEVRVTALDYEGGNFIDDLKKGDLWYFPSGVPHSLQGLSPNGTEFLLIFDNGHFSEESTFVLTDWLAHTPKSVIAKNFDLDPEVFARLPESEKYIFKGRNPGPIKDEAPKGKKAKKSKYNFTHRMLDQEPLKTSGGQVRITDSKNFPISKTVAAAHAIIEPGAIREMHWHPSADEWSFFIKGRARVTIFASEGNARTFDYVPGDVGIVPKNMGHFVENIGDEPIEMLEIFRSDEFRDISLFKWMGETPKKQVIDTLFADDPKNAAKFWDRIKDADNDVITKPDFVRSKPEADEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXT7</accession>
    <name>X0CXT7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_09107</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXT7"/>
    <dbReference type="eggNOG" id="ENOG502SKG6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_6_3_1"/>
    <dbReference type="OrthoDB" id="2496787at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF143">
        <property type="entry name" value="EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="14" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 17" id="KW-0732">Signal</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937311" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="18"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="422"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="436"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="31"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK87272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="454" mass="50869" checksum="BA36927B5FFAA1EF" modified="2014-05-14" version="1">MKWIVPFLVAFVPLVVAADATKELLTNLPACAAPCYEDAITKSECKSSDVKCVCSTQVIIQTAEACAAQACHVRDSLTTLNMTYTYCEVPVRNKTPIFINVTIVLGVISGVATALRLWSKFFFTKTELGLDDLFIVLTLFIGMPSTAMNIHGTAGHGEGRDIWTLEFDDITQFGFYFWLLEIFYFAQVSLLKTSLLFFYLRIFPGTAQKLLWGTIIFNSVFGVLFMFLAAFQCTPVSYFWLNWDGEHKGTCMNSTAIGWANASISVAVDVWMLAVPMWYLRKLKLHWKKKIGVAAMFIVGTFVTVVSIIRLQFLVDLGSSHNPTYDQTDISIWSTVEINVGIICASMPALRVILVRMFPALGGSSYDSSKYNNYGEHYGRKSHIMSRSRARVELPSHTGDSIHTPEHGGIELQRTFHVQYSENDEQSLVNGESKFNKTQVTTQMRSESPSDRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY14</accession>
    <name>X0CY14_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY14"/>
    <dbReference type="eggNOG" id="KOG0805">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_6_2_1"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07564">
        <property type="entry name" value="nitrilases_CHs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.110.10:FF:000042">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044149">
        <property type="entry name" value="Nitrilases_CHs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044:SF1">
        <property type="entry name" value="CN HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044">
        <property type="entry name" value="NITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK99415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="343" mass="37577" checksum="AFFE7F89A5A7972E" modified="2014-05-14" version="1">MDYKVVVAAVHAAPVFMNKAATTDKVINLIEQASKESIELLVFPETFIPGYPYWIECYPPLQQVGALAKYADESVVVQGGDEIARISAACRRTGVAISLGISERIAQGYTLFNSQVNIDANGTLLGVHRKLQPTYVERSVWAQGGGHTLRTYRLTASGRPFNLGGLCCWEHTMNGARQALITQHEHIHAGAWPALSTMAGFEAVADSQIEALMKAHALTAQVFVITASNYVDDTCLEWMEKNLGKQEFVKAGGGWSAVIHPFCSFLAGPHTGAEEKLVKAEVDLSQLGQVKVWVDAAGHYQRPEILKFSFDDQPLWADEKAAPGRSSPIKNNHEEEPVPKLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYE1</accession>
    <name>X0CYE1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleosomal binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_03381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYE1"/>
    <dbReference type="HOGENOM" id="CLU_063751_0_0_1"/>
    <dbReference type="OrthoDB" id="5241710at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK96293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="28488" checksum="A52A92504B180CF4" modified="2014-05-14" version="1">MPSDTPSEADSMAHHRPPASHRTLRLVAIASFLPAFPLCIAHGVLSNDAAPAVGLVPLAFSSGGSLFLLRRRERDDGLAHKLSHPVMAFAFDVVLAAACMIVLVFTWISKGQLASLSMLAAYATIPLLVNFVIHLLIALESFYTGLAVHSIVQWLAWRTLPPDCPHCDHRLRPDFPELPWLDRLREQRGDYSALFVDEENRYHDDETEETLQRAESAAQEAEAQPEVVDVRKKNNRRNRTNTPPSRDEPASPWSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYL1</accession>
    <name>X0CYL1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYL1"/>
    <dbReference type="HOGENOM" id="CLU_2223394_0_0_1"/>
    <dbReference type="OrthoDB" id="5105790at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="87" mass="10109" checksum="E3BB9A8138565190" modified="2014-05-14" version="1">MSVNLPADHVEVAALRDRVKHISEENKFVNNENEYLQESNDGLAIENNKLKKTLALTEERLQRITDFWRSAEEELTKQIAINEDLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ30</accession>
    <name>X0CZ30_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01951</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ30"/>
    <dbReference type="eggNOG" id="ENOG502QRN9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092544_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032263">
        <property type="term" value="P:GMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046100">
        <property type="term" value="P:hypoxanthine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032265">
        <property type="term" value="P:XMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000033">
        <property type="entry name" value="Xanthine phosphoribosyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363:SF1">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="206" mass="23004" checksum="2C388CC2D5785983" modified="2014-05-14" version="1">MVEKLYVTYNDVHKMCQKSAEKLLADFQPQLLIAIGGGGYVPARILRSFLKKAGSPNIPIQAIGLSLYESLGNDEVEAPGTKVTRTQWLDLTALGEMENLVGKRILIVDEVDDTRTTLEYAVKELEKDVEIARQRMGEGAPAPKTEFSIFVLHNKDKPKKGKLPDDMLATRYSAAETVGDVWINYPWEAIDIDEHDRNASLQTKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZL7</accession>
    <name>X0CZL7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02148</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZL7"/>
    <dbReference type="HOGENOM" id="CLU_2096991_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="116" mass="13514" checksum="D6CE125097AC79FF" modified="2014-05-14" version="1">MGSSIVSRHHDLFTLCSMKGTFRTSTGFTKSYGSFFASLLETAPFPNLCEKDELQQVVDVFLVPRRDKRLEMLDDLGMRCYRYCDPVVVLFDQLEDILLPSFLRQPHRFYLCFCLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZN1</accession>
    <name>X0CZN1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08770</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZN1"/>
    <dbReference type="HOGENOM" id="CLU_009665_6_4_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="10"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK87907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="440" mass="48775" checksum="B525E9C304715479" modified="2014-05-14" version="1">MSAQKDSFKLEVAIAGGGIAGLITAIALLKHPNVNVQVYERAPEFKEIGASIALGPNGLRTLDRLGVQNALAEGFAQRQKSGYPMIYRHWKTGEVIDHDVHNTVQSKKHATARFHRAHLHHALLENLPEGIVHLGKTTVDVKADPDEGATLYFEDGTTATADIVVGADGLRSKVRKTFVPEHELHWTGWVAFRAVFDADRLKDVEYPEDAAHWAGHETTFFHSHLGKGLFTIVGGYHADPKDPKSPGQDAKWDEDGSVEEFKRLYQHWNSTIRAFIDATPYVKLFPNYAGAALDTWSFSDRVALVGDAAHTHGGSFAAGGSLAIDDAYALYRSLDHIWPPSLAQTGKPTKAQLAQVFKLYEATRKPHLDKLLGIVHKNISGQKSNIDRATTETDEQLIRRVKGRMNPSWISEHDVVAAFERAVERIEGREKTVEEPRARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZT8</accession>
    <name>X0CZT8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZT8"/>
    <dbReference type="HOGENOM" id="CLU_3351091_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="37" mass="4359" checksum="1056EB15FD7D8068" modified="2014-05-14" version="1">MFFLSDYPYIMTFLIPFTDRVDILNFDGFPADTPLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZU9</accession>
    <name>X0CZU9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Vacuolar protein sorting-associated protein vts1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_08831</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VTA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZU9"/>
    <dbReference type="eggNOG" id="KOG0917">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030378_0_0_1"/>
    <dbReference type="OrthoDB" id="391137at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.270">
        <property type="entry name" value="Vacuolar protein sorting-associated protein vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044538">
        <property type="entry name" value="Vta1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039431">
        <property type="entry name" value="Vta1/CALS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023175">
        <property type="entry name" value="Vta1/CALS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041212">
        <property type="entry name" value="Vta1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04652">
        <property type="entry name" value="Vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18097">
        <property type="entry name" value="Vta1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vta1/callose synthase N-terminal" evidence="10">
        <location>
            <begin position="14"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Vta1 C-terminal" evidence="11">
        <location>
            <begin position="353"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="155"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="254"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="297"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK87977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="391" mass="42204" checksum="315D392AA512974B" modified="2014-05-14" version="1">MAEPLPAALKIPEVSRFINRANQLRSIKPAIAYWCEYHAVNQIVGKSLHTTDDDTFEFTKTLIERLEATKTERADDDAIVDNAAGQAYVEQFAQQTFERAERTMRANKVTRQTADTFDAAATFFDLTREWGEPDPEVVKKIKFAKWNAARILKAIREGKDPNETNPNAPEPEPEVALDPSDPEVQLLSGAPRASVEDAPDAGEPPSVPTFTDAPPRIPDDPGYFPPQPEHQPQAPEPFVPSPLSQSPTPGLSGGPPPPPPVGLPPAVSPVPESPAQPATQIPPQPSPQIPTKLPSQFAPPPPEPFTPSAPPSWTTTPSAPHPAASNPAPVIRQAPAPQPPAPAQTTGFATDQRDINQAQKHAKWAISALNFEDVPTAVQELRNALRMLGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2Y0</accession>
    <name>X0D2Y0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02669</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2Y0"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000004">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF9">
        <property type="entry name" value="HECT-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="883"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="58"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="181"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="250"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="305"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="466"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="758"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="478"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="612"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="1198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK97484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1230" mass="139029" checksum="FAA303D3B200550B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3L3</accession>
    <name>X0D3L3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3L3"/>
    <dbReference type="HOGENOM" id="CLU_3260561_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL01017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="42" mass="4669" checksum="30C3AF87C903B657" modified="2014-05-14" version="1">MIRAGCASNARPCHQQVTSEFRALNGVRELSSRMDTRYVGCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3V9</accession>
    <name>X0D3V9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_07968</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3V9"/>
    <dbReference type="eggNOG" id="ENOG502QR7H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1621678at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="62"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK89342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="303" mass="32473" checksum="AFD828AF3340E0CC" modified="2014-05-14" version="1">MSRVWTSATLRLRPALTPNTLQPRVVTRNMSGLSAMQASNRLRTALLEGKKAFGAWQMLPGANVSRVLARSGVDWVLVDCEHGNLDDGAMHDAVPAIAALGVSPIVRLPDMQGWMVKRALDSGAHGIVVPLLRTPEEARQLVQSAKFPPLGRRGFGSPIAPERFHPEPSFSEYLQQANDSLLTIVQIETKEALESIDEIAAVDGIDVLFIGPFDLGNALGHPIIEGVMATELKDAIAKILAAGQKAGKKTGVYCTGGEQAKIYADQGFDMMNVVTDYTSLGLVAKEQLSFADGSLAPTRGKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3W7</accession>
    <name>X0D3W7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3W7"/>
    <dbReference type="HOGENOM" id="CLU_2184051_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="109" mass="12003" checksum="4EFF6A3E0D23CBAB" modified="2014-05-14" version="1">MLHYHNIIPLYMASPRGTTYSIDHAQQNATTGVRHTGPWQHRVKSVTLITSGPLILNYSSHTGTSEMNQIVQFRETDPAETGKTGTSLLDGEVSSHCFPQVSLGSCEYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0D558</accession>
    <name>X0D558_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01219</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D558"/>
    <dbReference type="HOGENOM" id="CLU_164892_0_0_1"/>
    <dbReference type="OrthoDB" id="4981643at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="122" mass="13911" checksum="7A81F77000CC68FB" modified="2014-05-14" version="1">MYRLLSPKKRPDREVEACCILSKDVDTPGPKNLVRALEDYKLEQDQSFEDWVKTILMLLAPNMVESTVLIVSERGAMHVFKNNPYIIADAILDGVYQVASSPKHRLGNKVLSGIYERKESQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0D771</accession>
    <name>X0D771_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pre-mRNA-splicing factor SYF1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Pre-mRNA-splicing factor syf1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_07266</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in pre-mRNA splicing and cell cycle progression.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D771"/>
    <dbReference type="eggNOG" id="KOG2047">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007736_0_0_1"/>
    <dbReference type="OrthoDB" id="10067343at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000666">
        <property type="entry name" value="DNA repair and transcription protein (Xab2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000023">
        <property type="entry name" value="Pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000038">
        <property type="entry name" value="Putative pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056350">
        <property type="entry name" value="HAT_Syf1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23220">
        <property type="entry name" value="HAT_Syf1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="15">
        <location>
            <begin position="23"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor SYF1 central HAT repeats" evidence="13">
        <location>
            <begin position="186"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="14">
        <location>
            <begin position="401"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="791"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="793"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK90492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="822" mass="95170" checksum="3152D422022D442D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0D891</accession>
    <name>X0D891_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiol methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_06965</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D891"/>
    <dbReference type="eggNOG" id="ENOG502QS1V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056435_7_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183:SF11">
        <property type="entry name" value="THIOL METHYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK90832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="31143" checksum="D22832DD10BF2E7A" modified="2014-05-14" version="1">MATENPLEDRISTVPFAEQGEKWDSCWREALTPWDRGTASIALHDLLAQRPDLVPPSQHHDHRGHPLRDSTGAIEKKKALVPGCGRGHDVLLLSSWGYDVWGLDFSAAAKEEAIKNQKQAELEGLYKPVDGLDKGKIHWITGDFFGQDWAKGAGADGKFDLIYDYTFLCALPREARPKWAKRMTELLSHDGRLVCLEFPSTKPMSANGPPWGVSPELYEALLAAPGEEIAYNDDGTVHEDPCSKPWADALHRLSLLKPTRTHKAGTSPDGAVLDFLSVWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8B2</accession>
    <name>X0D8B2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8B2"/>
    <dbReference type="eggNOG" id="ENOG502RJRA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048911_0_0_1"/>
    <dbReference type="OrthoDB" id="3513892at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="3"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="368" mass="43435" checksum="56FEB6147DE15AC7" modified="2014-05-14" version="1">MANFQNLPPEIRHEIYLLATPARVVHVKAEFVNVDECYTLWRVSSYQGAFCHWRQSKNYENRVRVYFYSNAPIPVLLHTCFESRDFLIKMGYQLALKTKSHGPRTWFNYDRDVLFKDENTCDVAQFDPGDAIRVRRLAIGGFSHCLYEVPGDLEPARWHNCHRFCLYPQYKEFTALEELLVVDWTRNAFPRGLTRDTGYPAKPPPKRHRYDTGNLWKCVKVEETSLLRTMYHYDPREESHYGPKIDKPRGYGPAPNIADWGTFGTRSAYLQLELVRCWKSQNGSAGEWRAPRITLMHLIDERQEEILQQKQKMDVDELRGLQEYWAPALKERKERIDAGVGVISSLELRYLWANRWEKTCWIEKDIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8J9</accession>
    <name>X0D8J9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8J9"/>
    <dbReference type="HOGENOM" id="CLU_155364_0_0_1"/>
    <dbReference type="OrthoDB" id="5072693at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="15671" checksum="DD9F76D8269F536D" modified="2014-05-14" version="1">MSKRVASEASQATISIDLEIEIEHAKKAKSVGFEKRILLQIMASKSYWGNGPDNTAATGLKVVEMNRGKLAGRTTRMADVKTMVCKEKEWTAKTSATLQKQESNWNRTKKEEVGRRKEENLRSQRRRFRFEVRPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0DAD2</accession>
    <name>X0DAD2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Syntaxin 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_06288</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DAD2"/>
    <dbReference type="eggNOG" id="KOG0809">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038177_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15845">
        <property type="entry name" value="SNARE_syntaxin16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.70:FF:000021">
        <property type="entry name" value="SNARE complex subunit (Tlg2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF83">
        <property type="entry name" value="SYNTAXIN-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="247"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="199"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK91542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="344" mass="38644" checksum="C729EA25E7A4A231" modified="2014-05-14" version="1">MWRDRTNLYISYRQSYAHHPTQRRPYGPGALASGPFADTYTSSYANDDRRGLLSAGAFEDDGDAVIEMDLLPPRWADVSDEITDLLANIATKGQSLEKLHQKHVLPGFNDEDAKRAEEAQIEKLTQEITKGFHDCHRCIQRIEQMVRESQHAGTITRAEETMAKNIQISLAARVQDASASFRKKQSAYLKKLRGMGGFGGLSPGERSGTPQPGSYLDPSLQESDADRSFSQSTLQATQKQRVLHSNDAAIAQREREIEDIAQGIIELSDLFRDLQNMVIDQGTMLDRIDYNVERMNTDVKAADKELVVASGYQRRTTKRKIILLLILIIFGMIILLVIKPKKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0DDD6</accession>
    <name>X0DDD6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DDD6"/>
    <dbReference type="eggNOG" id="ENOG502RABX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1578568_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="88"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="165" mass="18867" checksum="D966E09C6B712BEC" modified="2014-05-14" version="1">MLRGLSVRQQEKSQEKKAARLRTQNWTLPDSGECKSWSLEEIQQEYEILLKKYKETTRDQNYLVNASISNKKAISNAGNVANQCREWINDCKKTLQSLEEALRLIINKKEAQAAIAQACKHPVPDNVHLAMKEISDADKRIAALQAQIRGYADALRQWLDKEPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0DFN6</accession>
    <name>X0DFN6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DFN6"/>
    <dbReference type="eggNOG" id="ENOG502SX1S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072359_0_0_1"/>
    <dbReference type="OrthoDB" id="10057496at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="242" mass="26015" checksum="491672E0AA699565" modified="2014-05-14" version="1">MSGWNPINGRDATGSRPNYSPVGAPIPSQGQPYVPHLGGPGYNFGLASPVYGYMYPGAAAYGQPVYGFPPQGPVAGFQTQQTYAHQPNGTGNILPRQAQPIPQIDPKMPAAQMTNSSGGVGCEPGYNYFFPANHTKVHVFKSDIPPWQLQANAQIPFIASHVPTSTKLGDLLKGFGCTNPSAKKNICFELYSGGNGKWYKGYSFTGDDKDEIGKTMDEVGWDSSRTGNKGEKPVVCLWFCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0DGJ4</accession>
    <name>X0DGJ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_04862</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DGJ4"/>
    <dbReference type="eggNOG" id="KOG2493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015355_3_0_1"/>
    <dbReference type="OrthoDB" id="260807at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF80">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="545"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK93607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="575" mass="62594" checksum="803E48F364DE08D9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0DMN5</accession>
    <name>X0DMN5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alcohol dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="9">1.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_04167</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a primary alcohol + NADP(+) = an aldehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15937"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:15938"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:15939"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.2" evidence="9"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DMN5"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_2_1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008106">
        <property type="term" value="F:alcohol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000158">
        <property type="entry name" value="Zinc-binding alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="12">
        <location>
            <begin position="5"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK95617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="360" mass="39175" checksum="17170AE6CEB54D48" modified="2014-05-14" version="1">MGYPDTFEGFCVDSPKSWNKFQKQTLKPKTWGDRDIDVEIEACGVCGSDVHTVTGGWGEFEGPLCVGHEVVGKAVRVGDNVKDIKVGDRVGVGAQVASCLECKLCKNKNENYCPDMVDTYNCTYPDGSVAHGGFASHIRAHEYFTFKIPDALKSEQVAPLLCAGITTYSPLVRANVGPGKTVAIVGIGGLGHMGIQWAKALGAEVYAMTHSPSKVEDAKKLGAKEVIVTTDENWADKYKFTFDFILNCADMTHKFDMSAYMSTLNIGGEFHNVGIPDEPLPQMTAGTFAGNAGKITGSHLGNHQEMDAMLKLAAEKNIVAWVETIDISEKGCAEAVERVKENKVHYRFTLTGFEKVFKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0DQ96</accession>
    <name>X0DQ96_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial distribution and morphology protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Mitochondrial inheritance component MDM12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MDM12</name>
        <name evidence="12" type="ORF">FOQG_03498</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion outer membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="9">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MDM12 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DQ96"/>
    <dbReference type="eggNOG" id="ENOG502S3PB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026794_0_0_1"/>
    <dbReference type="OrthoDB" id="3356905at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21672">
        <property type="entry name" value="SMP_Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03104">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027532">
        <property type="entry name" value="Mdm12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26544">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="1"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="66"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="172"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK96482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="419" mass="46031" checksum="0543A179836BA799" modified="2014-05-14" version="1">MSIDLNWETLTSGPDGDALAERIREFVHEKFQTVPLPKFIRSVNVHGFDFGTIPPQLELKDITDPLPDFYEEDLDDDEEDSEEEPSPPPPPEPTRMRPGPTPWGGPTRRGGGLRSEVLRNEMMGHDLGSPFLGTSTPGILGGSGLGYFQSHLGTGTHTPLAAVASAHHTNWMSVPGTPAREWGAPSHTRNPSQSSLTSVDNFKSSLDPLQSLREKGSVSTLAPTSVEASRPPTRDTHLGGSAIEDDDEEEGEEEAGRRPREPRVEDVQAVFRIRYNGDIRLNLTAEILLDYPMPSFVGIPLKLNITGLTFDGVGVLAHIRKRVHFCFLGPDDALAAVGPDDTKEEGGSSTSTADAKNEHHKPRFGGLLQEIRVESEIGERVGGKQSLKNVGKVERFVLEQVRRIFESEFVYPSFWTFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0DR49</accession>
    <name>X0DR49_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02166</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DR49"/>
    <dbReference type="HOGENOM" id="CLU_011581_0_1_1"/>
    <dbReference type="OrthoDB" id="2563500at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF7">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="4"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="93"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="598"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK96737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="672" mass="75983" checksum="D2700A825B37817F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0DUT3</accession>
    <name>X0DUT3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DUT3"/>
    <dbReference type="HOGENOM" id="CLU_2073239_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="118" mass="13284" checksum="7FB2FDF65FF32EE0" modified="2014-05-14" version="1">MGPLSSRRRLDPFTRSTAQRVREDVERLTPAAPSLPMMVVSTSQASRAMTTHQALEEKKSIKPPNRCQARDRRKSQKAGRIWSQPYYIPSDTMPTQFQALLNDLHLADTGDGEDSEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0DVR6</accession>
    <name>X0DVR6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phthalate 4,5-dioxygenase oxygenase reductase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_01249</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DVR6"/>
    <dbReference type="eggNOG" id="ENOG502S8QJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_17_2_1"/>
    <dbReference type="OrthoDB" id="5390at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06185">
        <property type="entry name" value="PDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.20">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052353">
        <property type="entry name" value="Benzoxazolinone_Detox_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005163">
        <property type="entry name" value="Tri_helical_YiiM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30212">
        <property type="entry name" value="PROTEIN YIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30212:SF2">
        <property type="entry name" value="PROTEIN YIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03475">
        <property type="entry name" value="YiiM_3-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00409">
        <property type="entry name" value="PHDIOXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="4">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="5">
        <location>
            <begin position="139"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="3">
        <location>
            <begin position="373"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK98282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="50508" checksum="3903D411CECAA6E7" modified="2014-05-14" version="1">MNMSETNVCIGDIFRIGRDVIIQVSGPRQPCYKLNHRFQHKKISAMTQSSGRTGWYYRVLETGFIEQGDAMELVERINPTWSLSRVQKYLYHEKDNIETFQELVSLPALSEEMVGIFQDRLDHGTEDMSGRLEGDGVPVVWRPYKLASKTELTPRIKSFILESQEQNEDSEFGQFPFVRVQFGPDGNMSRAYSVVSGTTSRFELGIARDDNSRGGSIYLHDNLNVGDTIKVAPGHNATGTQKEKMETLASKHIFIIGGIGVTAFLGEIEKLSREPVEVEVHYAVRSRNDAAYLSRLPLDKTTIYAKDQGQRLILSQIIPEPTVDKGRRPIVYCCGPTSLMNACRNLTTDSGYPKANVHFEEFGDATTGTGDPFEVEIKSTGQTVQVPREKSLLQVLSDAGFEIESSCLVGNCGTCMVNYYKGDVDHKGVALDEEQKKGYMLSCVSRGKGKIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B413</accession>
    <name>X0B413_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979497">
        <property type="protein sequence ID" value="EXK76496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B413"/>
    <dbReference type="HOGENOM" id="CLU_3193950_0_0_1"/>
    <dbReference type="OrthoDB" id="4150019at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="46" mass="5051" checksum="FFD2004A744F9F28" modified="2014-05-14" version="1" fragment="single">MAGNPPFVIESFPPQCAQTPPGLGLMLPRGTNNEPSRENQSTKRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8A3</accession>
    <name>X0B8A3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658552">
        <property type="protein sequence ID" value="EXK78006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8A3"/>
    <dbReference type="HOGENOM" id="CLU_030115_2_1_1"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="86"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="476" mass="55489" checksum="F7CE34A9DACEC76B" modified="2014-05-14" version="1">MSSMLCFNCFASALRPVSRVFRIFFHERHPTAIDHYPPTPEQLNGQKQAFIDSIDHDAVCRLASRHNNEEPCHIFDSKHGSFNACFFVEFPSSGTRWVVRIPIDPVVSEVWTKLQSEVATMQYIKKKTKIPLPDIHAHGRNEKLVRDSSTTQAFLILDFVSGRPLDLQALRDDTLPRRKHFYAQLIEVMAQLRTLEFTKSGSLMPDREAVPDNALSIPLNEFQVASNQARFLPMAQSARKFALNQLNLIREEYRLPRSELSRETVEMEIFALNHLKQLTQGLADDRKCFVLSHSDLRPANIIVDDDLNITSILDWEWTHTIPRQFFMPPSWITLHNLVKSAELGHSESFLEFCEVLEEMAKSSSLYRPLANEWDPDLPNKLLLPLSEILQHHSELLCIYYKFIFPQCFQKRRQEVVAEFFRSSKSRSSEVQGRMEDSNRYIQYLKDKRLYIPDEQIREEREWIEIARQLDKKLGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9G3</accession>
    <name>X0B9G3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16916</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658522">
        <property type="protein sequence ID" value="EXK78401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9G3"/>
    <dbReference type="HOGENOM" id="CLU_065853_1_0_1"/>
    <dbReference type="OrthoDB" id="2101473at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007396">
        <property type="entry name" value="TR_PAI2-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802">
        <property type="entry name" value="PROTEASE SYNTHASE AND SPORULATION PROTEIN PAI 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802:SF1">
        <property type="entry name" value="PROTEASE SYNTHASE AND SPORULATION PROTEIN PAI 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04299">
        <property type="entry name" value="FMN_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010372">
        <property type="entry name" value="PaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="29610" checksum="55C44BA15E84C9C2" modified="2014-05-14" version="1">MYIRKDHAETDLRVLRRLVRENPLGLLTTVISSPSGSYPLAQASHIPWVLDIQNEESETELGTLRGHLARQNPQSKAIIEEATTKNTQVLQNDVLVIFQSPVHHYIPPQFLVETKPTTTKVVPTWNYAAVQIYGKAKVYVDSKSAETSEYLTSQINALTRHTEVNLMGFDGKDGNHEPWKVTDAPERYIELMKKAIIGIEIEIERFEGKFKMSQEETRGDSDGVIAGFRGLGTEAGQRVADLVEERREIKEKVKAAQVQKSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB71</accession>
    <name>X0BB71_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979887">
        <property type="protein sequence ID" value="EXK75714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB71"/>
    <dbReference type="HOGENOM" id="CLU_3207712_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="45" mass="4848" checksum="2CBED53588AC19B2" modified="2014-05-14" version="1">MRKQLVSDYYSAGSDRALIVRWTVAAGGSIACRPRHCSGSAALHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBD0</accession>
    <name>X0BBD0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_16291</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 13">
            <text>tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="1"/>
    <dbReference type="EMBL" id="JH658483">
        <property type="protein sequence ID" value="EXK79086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBD0"/>
    <dbReference type="HOGENOM" id="CLU_035267_0_1_1"/>
    <dbReference type="OrthoDB" id="197206at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023617">
        <property type="entry name" value="Tyr-tRNA-ligase_arc/euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050489">
        <property type="entry name" value="Tyr-tRNA_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264:SF4">
        <property type="entry name" value="TYROSINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264">
        <property type="entry name" value="TYROSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006588">
        <property type="entry name" value="TyrRS_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="321"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK79086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="359" mass="40367" checksum="9FA82A383409CDA1" modified="2014-05-14" version="1">MTPEESITLIKANLAEVMNPEIIDNVILKEKRPLCVYWGTAPTGKPHCGYFVPTINIAELLYAGCHVKILLADKHAYMDSLAPLEVIEHRCEYYRLLINSSLKAIGVDVSKLEFLLKAGSEVVKQAENPTLGSLEYPIWQSLDEEDLDVDAELGGVDQRKLFTFFIDHMPKIGYKVRAHLMNPMVPGLGEAQKMSSSEPSSKINLLDTLEEVAKKLRKAVCAPKRVEGNGIIAFIEHVIFRVESLKTGGKPRFTAETRDGEPLVYEHICKLKEDYESDTLTPQMIKSALIKALNDLLDPIRKDFDSGEDWKRVADLAYPAEVKPEKTKKEKKDGNRSQRLPIRTPIQQVTDEVPQPLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCF9</accession>
    <name>X0BCF9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658707">
        <property type="protein sequence ID" value="EXK76513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCF9"/>
    <dbReference type="HOGENOM" id="CLU_2873807_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="64" mass="7649" checksum="6671FCDB20C78A32" modified="2014-05-14" version="1" fragment="single">MERKSLQQSLERRAFITLTYIRRRRSNIEKLISAGIAYMTWLKLCTRMIMLRLNNMVAGSETRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD58</accession>
    <name>X0BD58_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658462">
        <property type="protein sequence ID" value="EXK79731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD58"/>
    <dbReference type="HOGENOM" id="CLU_083937_0_0_1"/>
    <dbReference type="OrthoDB" id="5103885at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="225" mass="25036" checksum="C4B6EE3F31D277E4" modified="2014-05-14" version="1">MYKLTSAPVRTHVTTEKQGGSFRTINSEHEGIQDEPCWKLGGYSMYHASQPGKLLGANNDDDYIKALDQSNVGDLMFVFGFVYHEYPPQTENGGVDLLALQKSICGDMIRPLGMTLESIGLSCGLNLKHKVNNQNLLSLSVAYNGITREFNLDETFVASQRDPAARTTYRMQCKSIPCTFNHIDISTPKIEETKWSGILDQHQSTAELMLANLFVVGIAFYSTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE26</accession>
    <name>X0BE26_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979457">
        <property type="protein sequence ID" value="EXK76709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE26"/>
    <dbReference type="eggNOG" id="ENOG502S6HP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017829_0_0_1"/>
    <dbReference type="OrthoDB" id="2922289at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788:SF1">
        <property type="entry name" value="IPA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="820" mass="94411" checksum="AB6B3F4AC4ECFCFB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BED8</accession>
    <name>X0BED8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979411">
        <property type="protein sequence ID" value="EXK77173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BED8"/>
    <dbReference type="eggNOG" id="ENOG502SJUN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007003_1_3_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="294" mass="33056" checksum="45E611FF8E8C9597" modified="2014-05-14" version="1">MPSSVPGFRRLVPAPVSTSESTSSGSDQGRPSLLSLLRPRANLTKIACESCRKRKAKARAEGCINRGVQCHYETSNWDLKRKYEEIREKSNTYEQLCYLLTCLPEREAQGILRRLREGADVATTMRQVKDGDLPLQPAWGPETRLHYKFPYSTSMPAALLSPDNPYLGSTVFEITSHALPQSAEQTEAWASQSKTIYMTPYNIAELMDPYIPNIQFSKWTSVETDDELLRALLRAFFLHDYANYTCFQKDIFLQAMRDGDARFCSPLLVNAVLAEACVGHENATARRSAKSLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFL8</accession>
    <name>X0BFL8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Right handed beta helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658432">
        <property type="protein sequence ID" value="EXK80950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFL8"/>
    <dbReference type="eggNOG" id="ENOG502R351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041546_0_0_1"/>
    <dbReference type="OrthoDB" id="5576103at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938439" description="Right handed beta helix domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="37141" checksum="D1E4DC2D45A5E110" modified="2014-05-14" version="1">MLHLSSVLTAGLALITAANAACGDGSPQGVVSGSGTFTATVNGANVYTGTDYRLAIQTALDRISSGQRVTVRASGSIGANTISITSGKTFEVCGTMNVGNKSGRGAIEAINQNDVKIPYLKMTGNPYFGLRFSGTRNLALGDITMNLSGGLGIRFDRDANWNYDVSMGNIVVTGAGSHAVETFKIDGLTITSVKAKDVGECGLLIQESRNVKVGYVEGVNVATGTGYATLRFANNNGQLANGQYTTTNVFVDKVYSRGGGRGIFCVSMSGATEIKNIDLADNGNNAILIENCYNFAIRDGVINGGGEVRVSARSEFPNTSGIYVKAQVNSNTVRESPCAENIYWGITGNAQKNIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGA3</accession>
    <name>X0BGA3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_17775</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979385">
        <property type="protein sequence ID" value="EXK77519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGA3"/>
    <dbReference type="eggNOG" id="ENOG502SJFZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016056_0_0_1"/>
    <dbReference type="OrthoDB" id="103349at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052701">
        <property type="entry name" value="GAG_Ulvan_Degrading_Sulfatases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43751">
        <property type="entry name" value="SULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43751:SF3">
        <property type="entry name" value="SULFATASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="3">
        <location>
            <begin position="435"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK77519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="846" mass="96111" checksum="6CC290EBD7BBD12B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH31</accession>
    <name>X0BH31_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH31"/>
    <dbReference type="HOGENOM" id="CLU_011226_4_1_1"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03038">
        <property type="entry name" value="GST_N_etherase_LigE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="24"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Glutathione S-transferase UstS-like C-terminal" evidence="2">
        <location>
            <begin position="183"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK81470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="30875" checksum="47CBF71EC17AB0B9" modified="2014-05-14" version="1">MSESSKKIVFYDITARQPVEKNCFSPNPWKSRFALNFKGVPYSTSWVALPDITKVRTGLNVPACRKFNDGKEFYTLPIIEDPSTGSVVGDSFDIAVYLQKTYPSSGGGDLFPTQTLDFDFKHPYILVPLSEWRDKENPEYARFNLNIDAAFTAHVQLGVQGMPFDPASEEESKAEFVRRAGVKQWDDFALVGEARDKVMKSLREMLGNLAKLFTRDASGPFLLGKKASYADMVVGAWLRMLHATLPEDEWAQIAGWHDGTFGQLHEALDAYAEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI26</accession>
    <name>X0BI26_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_14122</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI26"/>
    <dbReference type="eggNOG" id="ENOG502RD71">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_408845_0_0_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF305">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="6">
        <location>
            <begin position="532"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK81486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="674" mass="72335" checksum="A0EF91EAE1D31853" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJN8</accession>
    <name>X0BJN8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_16258</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979351">
        <property type="protein sequence ID" value="EXK79093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJN8"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="8120565at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF14">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="49"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK79093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="548" mass="60643" checksum="3089B5BCC0C963D9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK86</accession>
    <name>X0BK86_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_16486</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658496">
        <property type="protein sequence ID" value="EXK78874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK86"/>
    <dbReference type="eggNOG" id="ENOG502SJ1N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF13">
        <property type="entry name" value="SPECIFIC TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="618"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="159"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK78874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="792" mass="87896" checksum="4D44E64C8F6A5E32" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKR8</accession>
    <name>X0BKR8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_12999</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKR8"/>
    <dbReference type="eggNOG" id="ENOG502RVYG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008511_2_2_1"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF3">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="639"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="639"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK82725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="714" mass="79680" checksum="0C5FA2E68DB7EAEE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLI4</accession>
    <name>X0BLI4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_15672</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658461">
        <property type="protein sequence ID" value="EXK79748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLI4"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00173">
        <property type="entry name" value="EDTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="444"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="56"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK79748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="499" mass="54507" checksum="DCCD26E535A49F19" modified="2014-05-14" version="1">MDIEKKPRASMDENESCDSKSQGQVISPKPEALQHLSDEEITALEKRLRRKIDLRLLPCMILIYIMNYLDRNAIGAARLGGMEEDLGLKGNEFQTAVSVLFVGYVLMQVPSNMLLNKIGKPASYLTACMIGWGVLCASTGAVHSFGALTAVRFLLGFVEAAFYPGAMATLSAWYVRKELGVRTAIFYSGSLISGAFSGLIAAGIIDGMNGVGGLLAWRWIFILEGSATVVIAFCCYWILPDFPATTKWLTEEERAIALWRMEVDAAGEEDWTAGDQQSLFHGFKLLLQDPKNWILIVVCYGAASAIAINSFFPTIVKSMGKDRITTLLLTAPPYLLACIVCAVVAWNADRVQERFWHTSLSIACALAGFIISASTTGIGPRYFGAMIMLPGIYSGFNMSMVWTANTNFRPVSKRAAALAFNNALATICSIYGSFLYPNGAEPRFILAFSVNAAMATIAIIASVALHFILKRANRKLELREAEEEAAGRHLPGSGFRYLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM39</accession>
    <name>X0BM39_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endo-chitosanase</fullName>
            <ecNumber evidence="10">3.2.1.132</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_12754</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin. Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endohydrolysis of beta-(1-&gt;4)-linkages between D-glucosamine residues in a partly acetylated chitosan.</text>
            <dbReference type="EC" id="3.2.1.132"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 75 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.132" evidence="10"/>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM39"/>
    <dbReference type="HOGENOM" id="CLU_046555_1_0_1"/>
    <dbReference type="OrthoDB" id="4756206at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016977">
        <property type="term" value="F:chitosanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009939">
        <property type="entry name" value="Chitosanase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061">
        <property type="entry name" value="ENDO-CHITOSANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061:SF9">
        <property type="entry name" value="ENDO-CHITOSANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07335">
        <property type="entry name" value="Glyco_hydro_75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK82921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="144" mass="15510" checksum="23242051BFE3F7D7" modified="2014-05-14" version="1">MDIDCDRATEVQVTVQMTLLVKDKPLSSYVVFGTKDFNPQDHGIEPLSVMAVVCRNQVFYGVWGDTNGFRSTGESSLALARLCFPNEGLNGNKSHGKKGVLFIGFTGKGAVPGANGANWKAKNRCQFQDSLKGLGDKLVAGLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP04</accession>
    <name>X0BP04_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_12116</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP04"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_4_2_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000386">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="368"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="60"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="491"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="512"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK83591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="525" mass="59412" checksum="8885B83B3289EFA2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP55</accession>
    <name>X0BP55_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_12161</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP55"/>
    <dbReference type="eggNOG" id="ENOG502SHQ6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027816_3_1_1"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000039">
        <property type="entry name" value="Neutral amino acid transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF697">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="49"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK83641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="470" mass="51266" checksum="ADF9D1C8B513F418" modified="2014-05-14" version="1">MAAQEVQQVVDDKVTPYRPADEEVVSIKGETLESHEVFQQTDDGVQFRTVSWQRATIIFLKIQFAMSILSVPGAFATLGAVGGGLSLVGWHTLNTYTAVILGEFRNRHPECHTLADMCGRLWGRVGKELVGLQILVAQVLISAAGIVSISTAFNAISNHGACTVIFTLIGAISITLFSSVRTFSRLGWLTWIGFFTFFVAVFIFVVAVTQQDRPAMAPQTGDYELGWTAIAHPTFVAGITASANIFISNSGSSMYLPVLSEMKRPEHFRKAVLVTGVLVLAMYLSFSLVIYRWCGVWLATPAFGSAGPLFKKISYGIALPGLIIGVGIYQHVAAKYIFVRILRDSHHLQENTMVHWTTWIGSNLTLGILAFIVAEAVPILNYLLGLAGAVCFAPFSLIFPALLWMQDFKHYRTGNSSNKAKYWSHALIVLVGSFMVIAGTYSVAVSIQDAYRSGLIAKVFNCADNSGTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR85</accession>
    <name>X0BR85_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">DNA topoisomerase 2</fullName>
            <ecNumber evidence="5 16">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">FOQG_14172</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14 16">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15 16">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="16">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the type II topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5 16"/>
    <dbReference type="EMBL" id="KI979332">
        <property type="protein sequence ID" value="EXK81433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001935_2_0_1"/>
    <dbReference type="OrthoDB" id="276498at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000819">
        <property type="term" value="P:sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16930">
        <property type="entry name" value="HATPase_TopII-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03481">
        <property type="entry name" value="TopoIIA_Trans_ScTopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03365">
        <property type="entry name" value="TOPRIM_TopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000003">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.30:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000008">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000004">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.670:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.199.10:FF:000002">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050634">
        <property type="entry name" value="DNA_Topoisomerase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001154">
        <property type="entry name" value="TopoII_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031660">
        <property type="entry name" value="TOPRIM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034157">
        <property type="entry name" value="TOPRIM_TopoII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169:SF38">
        <property type="entry name" value="DNA TOPOISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169">
        <property type="entry name" value="DNA TOPOISOMERASE/GYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16898">
        <property type="entry name" value="TOPRIM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01158">
        <property type="entry name" value="TOPISMRASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15 16" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13 15 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <keyword evidence="11 15 16" id="KW-0799">Topoisomerase</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936612" description="DNA topoisomerase 2" evidence="18">
        <location>
            <begin position="21"/>
            <end position="1737"/>
        </location>
    </feature>
    <feature type="domain" description="Toprim" evidence="19">
        <location>
            <begin position="620"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="20">
        <location>
            <begin position="873"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="86"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1251"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1364"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1441"/>
            <end position="1737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1262"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1390"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1483"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1503"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1524"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1549"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1589"/>
            <end position="1603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1634"/>
            <end position="1650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1660"/>
            <end position="1669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1678"/>
            <end position="1687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1713"/>
            <end position="1737"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="15">
        <location>
            <position position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00053943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EXK81433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1737" mass="194433" checksum="81CA92CF102B1C68" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS89</accession>
    <name>X0BS89_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4 14">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_10986</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4 14"/>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS89"/>
    <dbReference type="eggNOG" id="KOG3187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034302_6_1_1"/>
    <dbReference type="OrthoDB" id="46988at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102158">
        <property type="term" value="F:very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF3">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00036671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK85050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="214" mass="24465" checksum="5CA91B442ED1431C" modified="2014-05-14" version="1">MARPTSDSRPKPSAYLFLYNTLSAFLRTALLLRTTYLWLTQGNGAVWDELNIIARWTETFTVMEVIHAVTGLVRAAPATTALQVAGRNTIVWAITRNYPEVGFRDTAYSLMLMAWNAADAIRYFYFTLQTGTGSVPAGLTWLRYNMFIILYPIGILSEMKLVYEVIQPSQARNPTYQYLLWFGLAIYVPAFYILFGHMLSQRAKLNRPNLKKQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSG4</accession>
    <name>X0BSG4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_11051</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSG4"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="47"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK84806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="534" mass="57349" checksum="E059525529FBD4DC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVI7</accession>
    <name>X0BVI7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVI7"/>
    <dbReference type="HOGENOM" id="CLU_3191358_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="46" mass="5185" checksum="1C704185B19129C9" modified="2014-05-14" version="1">MLMQSTECGENLVSDVCIDFSQTPQDWSPAVAEEDKVFIHASIILW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW75</accession>
    <name>X0BW75_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09722</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW75"/>
    <dbReference type="HOGENOM" id="CLU_023880_4_0_1"/>
    <dbReference type="OrthoDB" id="270167at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF20">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK86450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="392" mass="43702" checksum="9628CA9B1B4AE651" modified="2014-05-14" version="1">MSIMTSPQRAPRVCRICKAKKKACGKELPTCSYCFKRGFDCVYEDESDTPPISDNVAEVLKPWSLTLFPMSISTTTLDRTMAYHLHYFYKVVGQSPLQAGKRFLDNFQRWLPIMAPRRLHEHIELSERGLPGADVSVLLLSICLVTLRSGGDLADPFLHHSVVYVTVKTLYAQVQAITHASIPLIQTGVILSAYEYASGQIGSAYISIAACIRMAQVVGVDAAYDKLGAVQEETRLHATSEWNLWWSIIVLERFILLEYSNTGRRDRMAVCPSSDVPLPSDTVSNSEYIPTYCTMSSSIIQSSSGLSSFGRQAQAIYLLDRCLYETSQSEQGDSEERLLKLQQLDKDLQKRLSVFMTQTPHEPGLRCGTIATVLIHSTRGDIVDSGLVACRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWE1</accession>
    <name>X0BWE1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWE1"/>
    <dbReference type="HOGENOM" id="CLU_3392424_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3262" checksum="FE1BB393682D81DA" modified="2014-05-14" version="1">MGDELSPTTVTAIEPASGVLPQVYVKIEASSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXJ7</accession>
    <name>X0BXJ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small nuclear ribonucleoprotein Sm D1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">snRNP core protein D1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_09491</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in splicing regulation. Facilitates post-transcriptional gene silencing (PTGS) by limiting the degradation of transgene aberrant RNAs by the RNA quality control (RQC) machinery, thus favoring their entry into cytoplasmic siRNA bodies where they can trigger PTGS. Does not participate in the production of small RNAs.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the snRNP core protein family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXJ7"/>
    <dbReference type="eggNOG" id="KOG3428">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123956_3_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097525">
        <property type="term" value="C:spliceosomal snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01724">
        <property type="entry name" value="Sm_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000008">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034102">
        <property type="entry name" value="Sm_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7 10" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="9">
        <location>
            <begin position="2"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="80"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK86626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="13326" checksum="27EA3F14070C5833" modified="2014-05-14" version="1">MKLVRFLMKCANETVTIELKNGTIVHGTISSVSPQMNTALRTVKMTIKGQEPISLETMNIRGSTIRYFILPDSLPLDTLLIDDAPKPKNKARKEAERGGRGGRGRGGPRGRGRGGGRGRGGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXN3</accession>
    <name>X0BXN3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658404">
        <property type="protein sequence ID" value="EXK83254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXN3"/>
    <dbReference type="eggNOG" id="ENOG502SXUK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038958_1_0_1"/>
    <dbReference type="OrthoDB" id="5062850at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="492" mass="56674" checksum="CD0B22C34E592A17" modified="2014-05-14" version="1">MFAQIDARFPRFRSMFESELANHNISNPVRDRPRSNTPIARMRPPLCPWVQYFFKLYVDGPDVYGPFALCSFADAHEGEYMDPLHRLGRGSHERWQEQSGDVRDALTYCLGLIAEKAPREFDNHVYKTLPHWVGKYQSQEFLRLNFNLWHIPSREEVAHALALLNIHEFVWKLPEIWTYPLGFYKELGDVPSKPRLENAERGQYAAEYDNPMRLVDHFDYRYLNKIRFSATATAIRFLNRLPAEQRTQIRKLALHEDSPSVNMPSLHAQGLVPLFKENPLLRVERRVSLFGCIDNFAGPHTDWKTRAKTNPFYGPSFLSKLQSWLIDALAMRDLDVPAGSFIFTLEGGTHGEFCTDVFQRCVLMGIAEGEAFNKCCELGLFTSIDSISGNPDYVPLDPRFKEAIEHLVNQTSILRSDFSPGVPVDPDTLVEESKGYDDVEDLVERWECGARYLSCKMPPDLFYDVMLPAKCDLQTREQYIESQGGRIKEQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BY91</accession>
    <name>X0BY91_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BY91"/>
    <dbReference type="HOGENOM" id="CLU_052246_1_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032451">
        <property type="term" value="F:demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070988">
        <property type="term" value="P:demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032857">
        <property type="entry name" value="ALKBH4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463:SF1">
        <property type="entry name" value="2-OXOGLUTARATE AND FE-DEPENDENT OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463">
        <property type="entry name" value="OXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="1">
        <location>
            <begin position="114"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="256" mass="29818" checksum="B297E232F2D7B647" modified="2014-05-14" version="1">MSRGLISYEDTDLELSHSSQLRYEIHQVIALKMEELPIKPSGIFMQQDFITPEHEQKLIHIFENELEWPTRPGRLSLHYGYTFSYKTFGIDEETPFKPFSEWLVPLLPTTEGRPPDQVCLQQYAPGTGIPPHVDTHGPFDQLYSLSLGSPLFMQFANKETGEKIEVDLLPRSMMQMSGDSRLHWTHGIKSRKTDTLPDGTVRLRQLRWSLTYRWLRKGAECECGNEILCDTAQRRKGIEREYRWKQYEEDAKAPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ63</accession>
    <name>X0BZ63_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein NRDE2-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11682</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NRDE2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ63"/>
    <dbReference type="eggNOG" id="KOG1972">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="297219at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902369">
        <property type="term" value="P:negative regulation of RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013633">
        <property type="entry name" value="NRDE-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471:SF0">
        <property type="entry name" value="NUCLEAR EXOSOME REGULATOR NRDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471">
        <property type="entry name" value="TETRATRICOPEPTIDE-LIKE HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08424">
        <property type="entry name" value="NRDE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="201"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="634"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1105" mass="126532" checksum="1998D5BA1057EA10" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C087</accession>
    <name>X0C087_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_19050</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="JH658749">
        <property type="protein sequence ID" value="EXK76192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C087"/>
    <dbReference type="HOGENOM" id="CLU_049768_3_4_1"/>
    <dbReference type="OrthoDB" id="4966at2759"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00642">
        <property type="entry name" value="GTP_cyclohydro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.10:FF:000003">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000012">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="12">
        <location>
            <begin position="2"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK76192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="190" mass="21389" checksum="F5A67F30F5431BC6" modified="2014-05-14" version="1">MQGAVRTLLECIGEDPGRDGLLDTPSRYAKALLFLTKGYHANVEDIVNNALFHEDHNEMVIVKDIDIFSLCEHHLVPFTGKESSPFPRYMHIGYIPSNTVIGLSKLPRVAEIFSRRLQIQERLTKQVAHAIMDILKPQGVAVVMESSHLCMVMRGVEKTGATTLTSCMLGCFEQKSKTRNEFMHYVGVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0M7</accession>
    <name>X0C0M7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0M7"/>
    <dbReference type="eggNOG" id="ENOG502S4C3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105924_1_0_1"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="23"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="167" mass="18943" checksum="25BEE04991F6FC39" modified="2014-05-14" version="1">MTRNPSSPPFTIRSHQPGDMGYITYRHGAVYAQEYGFNYRFESLIARITADFLDNFKPGLEGCWIAEKDGSFLGCIMLVQDKKPKTAKLRLLLVDESARGLGVGTALIQQCINFAREAGYEHIDLWTQSILEGARRLYKKAGFEMVETLNHNDWGVELTGEFWTLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0P6</accession>
    <name>X0C0P6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_09003</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0P6"/>
    <dbReference type="eggNOG" id="ENOG502SKCZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_2_1"/>
    <dbReference type="OrthoDB" id="5278984at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF55">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="37"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK87666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="367" mass="40389" checksum="44A0700CC9A0BE7D" modified="2014-05-14" version="1">MIDRGMGFPADGIDNHGWKLYITSLVMIISSGLFVVARCIARYSIHKLGSDDVAIIVSLISSVLLSTYIQLAIHHGYGMHKDDLEKPDLRMALKMFFIAQTPYKATVCLNKVAAILLYLRLFVTKSFRVWSFVVLGVVVGYSIGGIAATIWQCVPIKGAWDKSVDAKCIDSNKFWVAYAVLNILTDVMVLALPIMPIMRLQTSRREKLLLCCIFLLGGFVTITSILRVTSVSNSLKNKKDMTWNFIDRGVWTLIEANLGIIAACLPVLRQPMGKLFPRIFGSTKKSSLYYTGPGGPAKGYNLSDIAAQSPRPGLWKSDASRSEQIVSIGGPQTEASRDSDERCIIADSVKGSDFGSELATHKPDLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0Z1</accession>
    <name>X0C0Z1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_11082</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0Z1"/>
    <dbReference type="eggNOG" id="ENOG502SN0C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_29_1_1"/>
    <dbReference type="OrthoDB" id="5283415at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="47"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK84843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="405" mass="45305" checksum="B478A696D17EBA08" modified="2014-05-14" version="1">MASLHLYTRTGPPPYPNPLSLPTTPLQQKGLAALFLFPALSIIIVSMRMYSRVTSRTVGLDDWLVVAALFFALMMIGPLYMFMKLNYWGFHERDVPKDLNLAAGFWWNFLVQMFYNPVLALVKASILVFLLRLGGHKTNVRYAIYGLNIFNAAHAVAIFFTALFQCWPIEANWDFPLRKEPGVHCVNNWFHVIASCITIVTDFLVVALPFWIFLGLTMRWATKIAVLSVFLLGSVVGIIGIIRVISIYHQLVEGPKPGEDTFYSVLPVWGAVETNLAIICASVPALRPLFRRWFPALFGGSSDAPSGTPYGGRYANNSRGTGGMRSHNHDDIRLKDLRVSRTQHTEIRSVSPTGSEEEIMTYNGIMRTTNVQVAYENASKATVSESRTSSEIRFESKASEVRSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1G0</accession>
    <name>X0C1G0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1G0"/>
    <dbReference type="eggNOG" id="ENOG502T5C3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1161197_0_0_1"/>
    <dbReference type="OrthoDB" id="5103312at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="207" mass="23531" checksum="2488D962561D0B3A" modified="2014-05-14" version="1">MEQYQQTATGTTRHALQLPGDDPDDTTVNLILEDEDDPGYSLMIGDLIRRERHADVYSVYDPETGAKELRAEARAFVIDRVSGKLKKYRKRCTYRLGPRMYFSAPCRGARVIIYTTNPPDVATAKEGTHGLSEFSPRLPSGSNDSSTPSEGQQDERGQTQNADYKRESRRTRQLQRRRAKRHQGRTEKGLEGFQALNLRSPLEMKDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3I4</accession>
    <name>X0C3I4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">CNT family concentrative nucleoside transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_07999</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3I4"/>
    <dbReference type="eggNOG" id="KOG3747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016813_1_0_1"/>
    <dbReference type="OrthoDB" id="6075923at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="SODIUM/NUCLEOSIDE COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 28 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="609"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter N-terminal" evidence="9">
        <location>
            <begin position="224"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside transporter/FeoB GTPase Gate" evidence="11">
        <location>
            <begin position="305"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter C-terminal" evidence="10">
        <location>
            <begin position="409"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK88681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="648" mass="70748" checksum="466776DF4685C063" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C438</accession>
    <name>X0C438_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_08172</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C438"/>
    <dbReference type="eggNOG" id="ENOG502QRQD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027816_0_1_1"/>
    <dbReference type="OrthoDB" id="294730at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000039">
        <property type="entry name" value="Neutral amino acid transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF20">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="83"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK88911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="515" mass="56862" checksum="2D27BAB7F9238D0B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4B8</accession>
    <name>X0C4B8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">aromatic-amino-acid transaminase</fullName>
            <ecNumber evidence="9">2.6.1.57</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_07892</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an aromatic L-alpha-amino acid + 2-oxoglutarate = an aromatic oxo-acid + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:17533"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:73309"/>
            <dbReference type="ChEBI" id="CHEBI:84824"/>
            <dbReference type="EC" id="2.6.1.57"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.57" evidence="9"/>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4B8"/>
    <dbReference type="eggNOG" id="KOG0634">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_5_1"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047536">
        <property type="term" value="F:2-aminoadipate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008793">
        <property type="term" value="F:aromatic-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009074">
        <property type="term" value="P:aromatic amino acid family catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000074">
        <property type="entry name" value="Aromatic amino acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF21">
        <property type="entry name" value="AROMATIC_AMINOADIPATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="11">
        <location>
            <begin position="210"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00067014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK89220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="559" mass="61944" checksum="A05F91E859C27258" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4Q0</accession>
    <name>X0C4Q0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mitogen-activated protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_17585</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="1"/>
    <dbReference type="EMBL" id="JH658580">
        <property type="protein sequence ID" value="EXK77717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4Q0"/>
    <dbReference type="HOGENOM" id="CLU_011530_0_0_1"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000182">
        <property type="entry name" value="MAP kinase kinase kinase mkh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF48">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE BCK1_SLK1_SSP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="704"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="79"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="310"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="368"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="494"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="579"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="392"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="409"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="621"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="733"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK77717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1002" mass="109783" checksum="7E80B02DBFF2859E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C536</accession>
    <name>X0C536_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C536"/>
    <dbReference type="eggNOG" id="ENOG502SR0E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046874_0_0_1"/>
    <dbReference type="OrthoDB" id="1638493at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="14"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="437" mass="50504" checksum="F824DD626FB2E691" modified="2014-05-14" version="1">MVTSVNMALKMPKNHRLTGLPTEILLDIYQQLDLDGVFNLCATHRTLHELFDKRKASILLPVLVREFSPFDELLQVYTASVEDLDSRGGLYAPRRVVFKRFLGDTGMVLAPRSEHQPAVSADAVEGFITLNKPGKPIIPRAQPLKTVVLTENDLKPLLGYCSLVLRWQARFPQMRWFHEPENCRLLREHEAERFRRAMYRWWLYGFYFHGDFPRPRVGLPEPGVDDVRLSQLRLYSTCELVELMDLVETMKDVVLHYLCPRLDPSQDEYEGCDSYLYDVVDRPDSLARGWRDQSRWGRIVKTYCKLGPKDLMHLFENIYSYPRKRLITEARSLQPNLTFDQESISVSTQCVLDERQWSLNMPTLPLDGLGGVIDWDDERDAERVKFGSDASLDGTLPGGARMLRSSSHYSPRGDDGSYLEDVQRQTRMEGRYMVSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5D5</accession>
    <name>X0C5D5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Carbamoyl phosphate synthase arginine-specific large chain, mitochondrial</fullName>
            <ecNumber evidence="14">6.3.4.16</ecNumber>
            <ecNumber evidence="5">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Ammonium-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Arginine-specific carbamoyl phosphate synthetase, ammonia chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Glutamine-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">FOQG_07973</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CarB family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.16" evidence="14"/>
    <dbReference type="EC" id="6.3.5.5" evidence="5"/>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5D5"/>
    <dbReference type="eggNOG" id="KOG0370">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000513_1_3_1"/>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004087">
        <property type="term" value="F:carbamoyl-phosphate synthase (ammonia) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01423">
        <property type="entry name" value="MGS_CPS_I_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000004">
        <property type="entry name" value="Carbamoyl-phosphate synthase (glutamine-hydrolyzing)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000015">
        <property type="entry name" value="Carbamoyl-phosphate synthase arginine-specific large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1030.10:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="entry name" value="Carbamoyl-phosphate synthetase, large subunit oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CPSase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CPSase_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058047">
        <property type="entry name" value="CPSase_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003671">
        <property type="entry name" value="PRK05294.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009455">
        <property type="entry name" value="PRK12815.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF53">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25596">
        <property type="entry name" value="CPSase_L_D1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="Carbamoyl phosphate synthetase, large subunit connection domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="22">
        <location>
            <begin position="224"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="22">
        <location>
            <begin position="761"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="23">
        <location>
            <begin position="1026"/>
            <end position="1175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00068891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EXK89351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1175" mass="128973" checksum="E3AB660EB2BF6881" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5E7</accession>
    <name>X0C5E7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658554">
        <property type="protein sequence ID" value="EXK77977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5E7"/>
    <dbReference type="eggNOG" id="ENOG502SIVD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119621_0_0_1"/>
    <dbReference type="OrthoDB" id="3899536at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936183" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="21549" checksum="137B945A681E44FE" modified="2014-05-14" version="1">MHFTTAALSAIFASTALATPLSSRGHHDSDGDIFPDFGRYSDWAICKGKITKDRFPNLQAPNREGGCVRYYHGIDMTGVVTEQHFFFKDGFKTACDCAAKCLEEPTKCTNWVWKHTFMSEDGGKRSCTLYSSPNLPTEVTLKYDLANSKGFNLLQAANNPQAGAPAPLAFLDAAGTIPDKFGVSGFTVQDQNGRQFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C774</accession>
    <name>X0C774_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH:ubiquinone reductase (non-electrogenic)</fullName>
            <ecNumber evidence="2">1.6.5.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_07083</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a ubiquinone + NADH + H(+) = a ubiquinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:23152"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.9" evidence="2"/>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C774"/>
    <dbReference type="eggNOG" id="KOG2495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_1_0_1"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) (non-electrogenic) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF47">
        <property type="entry name" value="EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="12">
        <location>
            <begin position="114"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="13">
        <location>
            <begin position="509"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="475"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK90240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="577" mass="64159" checksum="318F00A66F19D8FE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7W2</accession>
    <name>X0C7W2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inositol polyphosphate-related phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658502">
        <property type="protein sequence ID" value="EXK78802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7W2"/>
    <dbReference type="HOGENOM" id="CLU_128897_0_0_1"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF1">
        <property type="entry name" value="SPHINGOMYELINASE DDB_G0288017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936821" description="Inositol polyphosphate-related phosphatase domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="63"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="172" mass="18837" checksum="3DD35F70D3ABC760" modified="2014-05-14" version="1">MSIRTVSSRLLAAALALGGLSMGQTTGNFNFLTYNVAGLPAIINNNEVPGDKATNANLIGTVLATQKYDIVHMQEDFNYHAYIYATDNHPYRTPTSGGVPFGDGLNTVANYDWTGLVRKKWNKCNLNSGDCLTPKGFSFMRMKIQGIEVDLYNLHADAGYVKSSTHVTDPPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8I2</accession>
    <name>X0C8I2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_08867</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8I2"/>
    <dbReference type="eggNOG" id="ENOG502S50Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042568_2_0_1"/>
    <dbReference type="OrthoDB" id="428177at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046355">
        <property type="term" value="P:mannan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937438" description="mannan endo-1,4-beta-mannosidase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="10">
        <location>
            <begin position="76"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK87518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="362" mass="39791" checksum="5588B2FF50258355" modified="2014-05-14" version="1">MKGLFTTLCLAFAHFCQLTEAKSSSWSGTNNYFLQGMSDSAQDAYIQTLSSYDTKVVRLWVNQASKGCQKGSQIVRDIPQLETTIGQYNKVTLDEIDKLLVKLSDKNIKAIISPHDANSLIGDYRKDAYWARWGSGYFYEKQDAFDAYDARLSYILNYKGTYSGKVWKNWPKAIFSFNLQNEPMTPGPSNCKNGDPSGWACGRATFMRNAGLDSHILISTGGLGGDFSHGCTFLPAVTQCKAIDAISVHRYASVPGMWGANLPNWLNQANGKKVYLEEWGVDSQQYDQKSAFVSEVNDMNSAGLPNMYWQLLPPSSGGCSYNPKNDAGDPFGIYTNSGVNLAGPINDATSSGAAQDWTGSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8I8</accession>
    <name>X0C8I8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658486">
        <property type="protein sequence ID" value="EXK79027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8I8"/>
    <dbReference type="HOGENOM" id="CLU_2158533_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="111" mass="13078" checksum="A4419900D66A0927" modified="2014-05-14" version="1">MPRTIDWGEGRYPKGNRCEYDNAKWKSGYGYWILWGTDRDNGGVYRRRHWYCSISCRNMDAECCDCNKEDDSSEDNSDDDDDDHDDDEEEEDDDSVDCVCQEMKAEDEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8L3</accession>
    <name>X0C8L3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_16294</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658484">
        <property type="protein sequence ID" value="EXK79052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8L3"/>
    <dbReference type="HOGENOM" id="CLU_005210_4_0_1"/>
    <dbReference type="OrthoDB" id="61110at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00625">
        <property type="entry name" value="RCC1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="28"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="29"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="89"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="213"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="268"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="310"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="375"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="105"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK79052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="440" mass="47030" checksum="0B342B27E31ADF2D" modified="2014-05-14" version="1">MAATRGSKKGSKFPQVGAKINKAPTQILHVYVFGEGSSGELGLGSRRIANKKPIDVKRPRLNFNLSANKAGVVQVSCGGMHVVALTNDNRIMTWGVNDQGALGRDTSWEGGIRDMDKSEDSYSDNEDDTSINPTESTPTPVLNEHFAPGTEFVQVVASDSATFALTEDGRIYGLGNISIQRSVQTTPVMLRNPKKIKALAAGSNHILAIDVKGNVFAWGCGQQNQLGRRIIARHKMSCLIPRGVCLPRGKISKIACGSYHSFALDTDGQVYGWGLNNFGQVGVESNAGEDDAITDIDGGGHHSLACSANGDIFTWGRVDGYQVGFEFDKLSEDNTIYDDRGNPRILFRPTVQPDPKNIVAVAAGTDNSFSIASDGQAFSWGFSGNYQTGQGTTDDIHTPTVMDNTAIRGKRIIGAGAGGQYSALFSLAEDTSLDPPNKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9D7</accession>
    <name>X0C9D7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Extracellular metalloproteinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_08716</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9D7"/>
    <dbReference type="eggNOG" id="ENOG502SUPZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008590_0_3_1"/>
    <dbReference type="OrthoDB" id="5332336at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09597">
        <property type="entry name" value="M4_TLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052759">
        <property type="entry name" value="Metalloprotease_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032475">
        <property type="entry name" value="Protealysin_N_PP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43579">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43579:SF1">
        <property type="entry name" value="NEUTRAL METALLOPROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16485">
        <property type="entry name" value="PLN_propep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Protealysin N-terminal propeptide" evidence="10">
        <location>
            <begin position="4"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Protealysin N-terminal propeptide" evidence="10">
        <location>
            <begin position="56"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M4" evidence="8">
        <location>
            <begin position="128"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M4 C-terminal" evidence="9">
        <location>
            <begin position="251"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="99"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK87823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="362" mass="40196" checksum="3EFD700BC8EC921E" modified="2014-05-14" version="1">MVAVPPHLLRAISKSKATTPEHREVARSSLAHTEQFLKNCQKRREQYLKTYNQVQQQIVPPQLFRNVIASDQADNAQRTRAKKSLDHLETIIGKVRGAQQALGSSQSSEPGTSHVVPSLTATDDPPYRAVYDIHESSNEGDLPGDLIRDNGKKEAEETKPSSDKAVNEAFENVGLVLGFYKKFFQWLSIDNKDMDVISTVHFGKQYENAFWDPEKLQMVFGDGGEFLNNFTGCIDVIGHELTHAVTEHTSPLDYYGQAGALNEHISDAFGIMVKQRVQDEKSDVADWLIGEDCILPGVKGTALRSMKEPGTAYDDPVFGKDPQVGHMKQFRTTFEDNGGVHIYSGIPNKAFYLASVSFGGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAG7</accession>
    <name>X0CAG7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAG7"/>
    <dbReference type="HOGENOM" id="CLU_3175399_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="47" mass="5057" checksum="AE6A3DFED2C8C695" modified="2014-05-14" version="1">MADRHAGSTQAPQHVLGRTMARRANSSDKAQQAGNDRLECGSFVTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB22</accession>
    <name>X0CB22_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Lysosomal dipeptide transporter MFSD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Major facilitator superfamily domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">FOQG_15550</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79415"/>
            <dbReference type="ChEBI" id="CHEBI:192470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:79367"/>
            <dbReference type="ChEBI" id="CHEBI:229968"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:79375"/>
            <dbReference type="ChEBI" id="CHEBI:229967"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79383"/>
            <dbReference type="ChEBI" id="CHEBI:229966"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79371"/>
            <dbReference type="ChEBI" id="CHEBI:84315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-arginyl-glycine(out) = L-arginyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79391"/>
            <dbReference type="ChEBI" id="CHEBI:229955"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79411"/>
            <dbReference type="ChEBI" id="CHEBI:229953"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79379"/>
            <dbReference type="ChEBI" id="CHEBI:229964"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-histidyl-glycine(out) = L-histidyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79395"/>
            <dbReference type="ChEBI" id="CHEBI:229957"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)</text>
            <dbReference type="Rhea" id="RHEA:79399"/>
            <dbReference type="ChEBI" id="CHEBI:229954"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79387"/>
            <dbReference type="ChEBI" id="CHEBI:229965"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79403"/>
            <dbReference type="ChEBI" id="CHEBI:229956"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-lysyl-glycine(out) = L-lysyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79407"/>
            <dbReference type="ChEBI" id="CHEBI:191202"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="19">Homodimer. Interacts with lysosomal protein GLMP (via lumenal domain); the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658455">
        <property type="protein sequence ID" value="EXK79872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB22"/>
    <dbReference type="eggNOG" id="KOG4686">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024516_1_1_1"/>
    <dbReference type="OrthoDB" id="424834at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="20" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="207"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="21">
        <location>
            <begin position="53"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00046376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EXK79872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="523" mass="57141" checksum="FBDA2669F8A941D6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD54</accession>
    <name>X0CD54_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_08033</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD54"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_0_1"/>
    <dbReference type="OrthoDB" id="5667at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF224">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="56"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK88734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="448" mass="48499" checksum="B8FACE70794EF516" modified="2014-05-14" version="1">MAAQDTTAPSSPRNSELTLQNQVGYNNEKSDLEEGNTQPEPAARPAGSGAPDGGLTAWLVVLGAWCTSFCSFGWINSVGAFQEYYQNDLLKQYSSSTIAWIPSLQIFFIMGMGPIIGKLYDSHGPRWLIFVGSVMHVFGIMMASISTEYYQILLSQGVCSAIGVSAIFQPALSTIHGWFDSNRGAAFGILATGSSIGGVIFPIMVTRLIKQVGFGWSMRICAFMILGLLIIANLTVRSIHPPNPQKVTRAQLVRPFHEPEFIFCMLGFFFFTYGLFVPIDYLPVQALHAGVDPNLVQYLIPILNAASLFGRVGSGILGDKMGRYNIFILVGFLSAIWILALWIPCNSQDGIIAFAALFGFCSGAYVSLIAPLVAQISPLPEIGFRSGIVFFVSSIGGLTTNPINGSILEKPTGWLGVKIFAGVFCLAGTMFILAARVHRVGWKITATF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEM1</accession>
    <name>X0CEM1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07917</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEM1"/>
    <dbReference type="SMR" id="X0CEM1"/>
    <dbReference type="eggNOG" id="KOG3502">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_178987_1_0_1"/>
    <dbReference type="OrthoDB" id="10258930at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000025">
        <property type="entry name" value="40S ribosomal protein S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00292">
        <property type="entry name" value="Ribosomal_eS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK89259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="68" mass="7766" checksum="14EA0B75C4566FB8" modified="2014-05-14" version="1">MDASKQPVKLVKVTRVLGRTGSRGGVTQVRVEFMDDQTRSIIRNVKGPVREDDILCLLESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFJ0</accession>
    <name>X0CFJ0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFJ0"/>
    <dbReference type="HOGENOM" id="CLU_1786951_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="145" mass="17036" checksum="4A771A417BA3E13B" modified="2014-05-14" version="1">MHRPGHDRRFLLTRFPIQRQACYYSVIVFMALRFPRLFTLLSLPFLSVKQDMTLVLGLSTHGHCSVEYDFGTGSLVNRLDSLTFRFGFGGVDKTWQSIHHFSVRHIRYQSWELDWGNAWIRGLNGRGYFHFLGVLRPNCFVLFPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFP9</accession>
    <name>X0CFP9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05366</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFP9"/>
    <dbReference type="HOGENOM" id="CLU_3392326_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3412" checksum="F139F6DA49430988" modified="2014-05-14" version="1">MKGDDVERVGGGHEDLSRNGMFRIAGGTFCKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGC9</accession>
    <name>X0CGC9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M50B-like-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGC9"/>
    <dbReference type="eggNOG" id="ENOG502QPXP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066780_0_1_1"/>
    <dbReference type="OrthoDB" id="40823at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049500">
        <property type="entry name" value="Peptidase_M50B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979">
        <property type="entry name" value="OS02G0221600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979:SF2">
        <property type="entry name" value="PEPTIDASE M50B-LIKE-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13398">
        <property type="entry name" value="Peptidase_M50B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="29554" checksum="17D1EF22F6EC609D" modified="2014-05-14" version="1">MAPHPDPSSLALEYTAENTINTLTRRDLQNPTHTQQVTLGIIGVYVVVIAILWNVPYVRMILWPFKMLVIAFHEFGHAFTALLTGGHVKSITLDPNEGGVTRFIGGRQGLTLPAGYLGSSIIGALLIFCGFNIVASKVASIVLGVCFLLTLWWGKRDWLTIATVLLAVGLLIACWFIEHAQALRFVVLFIGVMSSLYSVWDICDDLILRKVNESDASVFAKRYGGSSQCWGVIWGIISVLFMAAGIVAGLAAFSQSFAQQEKDSQKFMPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGM6</accession>
    <name>X0CGM6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_05463</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGM6"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_1_3_1"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="45"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK93336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="474" mass="51735" checksum="CF43E17CD747B095" modified="2014-05-14" version="1">MHNQTTNDIENSISLDDPQSPPSIPDGLKEEDRPVNWPSSKKWSIVVSTSLATFVVSFGSSVYSAAIPHIQARFSVSPDTALLGITLYVIGFALGPMAWGPASELYGKRRPLFLGYAIFCICQLPCALAQDVPLLLTFRFFSGLAGSSSLAILGGMYVDFLSRPAERGISTAVFSVATFCGPTVGPIVGNLATLKLGWRWTAWLTLIGGLVFGSVAFLLTPETSEVVILRQRSKGNTSVTPSRIYRPERGISIFLQSYLTKPVRMFVREPILIFFTIYMSLAYGIIYLTFTMYPFAFVTVRGWSRMDGSLPFVGMTIGVILACIGIALHSIYYIQQSRVHVPERRLPPMIAGSIFLSAGIFWFGWTSSTSVHWLAQAAAGVFLGSGSILVLMSGVVYLIEVYLVHANSALAINNFLRCVIAATFPLYATDLLVDAGLGVGGSVIGSICLALSPVAFLFWRYGRTIRQWSKFTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHE5</accession>
    <name>X0CHE5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial phosphate carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_04867</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHE5"/>
    <dbReference type="eggNOG" id="KOG0767">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039456_1_0_1"/>
    <dbReference type="OrthoDB" id="427452at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000024">
        <property type="entry name" value="MIR1p Mitochondrial phosphate carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF12">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="29"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="127"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="225"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK93611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="33603" checksum="F052C490DFC8479B" modified="2014-05-14" version="1">MAASTGSAKVDAVVQNIKAETPEKKTGLALYSRFALAGAVCCSVTHGGLTPVDVVKTRIQLDPATYNRGLVGGFRQVVQNEGAGALLTGVGPTFAGYFLQGALKFGGYEFFKQQWIDALGYETASKNRTAVYLASSATAEFFADIALCPLEATRIRLVSEPTYASGLVSGFGKIVKNEGVGALYAGFGPILFKQIPYTMAKFVVYEKVSEAVFRKFPKKDLSDGMQTVANLGSGLIAGFAAAIVSQPADTMLSKINKTQGLPGEGTVSRLIKIGKELGLRGSYSGIGARLFMVGTLTAGQFAIYGDLKKAMGATGGVEIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKN9</accession>
    <name>X0CKN9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKN9"/>
    <dbReference type="eggNOG" id="ENOG502SJWZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019524_2_0_1"/>
    <dbReference type="OrthoDB" id="4314040at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF11">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="498" mass="56041" checksum="3623E1213A6FCBFE" modified="2014-05-14" version="1">MPGVPSYKGCDACRKQKKKCDKAQPKCARCERLDIPCINVGKQRYKFKVQTLEQGDSISVQSIDTEDDTTSSSSRSSKSPISFTQALIKVPYNKTTMVTQTLVSRLEITDLRYDITCYGDFLRHIPARLGRNEALDASADALATTFSTLHRPQGYQTVDALTKYVKAISSLRLCLEDPAKARMPETMCSVYLIMICQGWLGRDDDPTTSHGQGLAYLLKAAARENWKAGFETDMLLTFCVPVIIESISNPKVRLEKWFWDMLDNFKKNNPPSTPESAKAQQDGQDAGGIPSLSIRNLGRLPDFINDPELHRMEITCAYHRLCRDLRKLSEIVKAVTWAPGFSPTPMQLRLSRSYNSAYSVLLTVLVIIGQLMQAFDPYNLALVGEAALCSSEVVSLAHRISQYRPLGASHVPLTLAIAWAATDEPGMKRQLEETLEEYQQDWTVTQWMKVGYWWTDKFAELRGRLAPRVSQEEEEMLIRRGEGVELKGQQPADECCVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLK1</accession>
    <name>X0CLK1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLK1"/>
    <dbReference type="eggNOG" id="KOG1530">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089574_0_0_1"/>
    <dbReference type="OrthoDB" id="566238at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01519">
        <property type="entry name" value="RHOD_HSP67B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086:SF10">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="85"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="192" mass="20964" checksum="8755DA54E2E55350" modified="2014-05-14" version="1">MASRRALFSSASRASAAIQPARPILIAAARSASPSLPSLAFAPFASTRSYASKAQAKAKPIADLAPRDPKPWNFEDIKNHVEKSDQGDVVLIDVREPVELFETGKIPGAINIPITSAAQSFHISDEDFEDMYGFQRPAKNKELVFYCKAGVRARAAAQLAHHAGWNKIGDYAGSWLDWEAQKGPVEKVKKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLU7</accession>
    <name>X0CLU7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_03988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLU7"/>
    <dbReference type="eggNOG" id="KOG0498">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016398_0_0_1"/>
    <dbReference type="OrthoDB" id="447251at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF2">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="354"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="414"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="458"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="622"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="463"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="622"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK95415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="664" mass="73831" checksum="71833ABC21D63DFF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMA5</accession>
    <name>X0CMA5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMA5"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="127" mass="14288" checksum="DF68F9F0532D36C4" modified="2014-05-14" version="1">MVWLSSEWTTAGPSDPAPFLPPLPMHLHIVPNNLMGISYLLNHECRSLIREMLCTSCPVRFNMGHGHPLPAAVTTQFKLSIIHRALSFAISSRVQVTESAEFTYIFPAYTNFKSQRSKTSCKPSYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMU5</accession>
    <name>X0CMU5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_05704</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the proteasome inhibitor PI31 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMU5"/>
    <dbReference type="eggNOG" id="ENOG502RZMJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044125_2_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045128">
        <property type="entry name" value="PI31-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013886">
        <property type="entry name" value="PI31_Prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021625">
        <property type="entry name" value="PI31_Prot_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13266">
        <property type="entry name" value="PROTEASOME INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13266:SF1">
        <property type="entry name" value="PROTEASOME INHIBITOR PI31 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08577">
        <property type="entry name" value="PI31_Prot_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11566">
        <property type="entry name" value="PI31_Prot_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI31 proteasome regulator N-terminal" evidence="13">
        <location>
            <begin position="27"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="PI31 proteasome regulator C-terminal" evidence="12">
        <location>
            <begin position="275"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="187"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="296"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="353"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK92628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="379" mass="40476" checksum="EF83994AD2FE5E4A" modified="2014-05-14" version="1">MSEPLSVAAILNGMADALPTHPPNDDSSDLASSYEVIALLIHSYLAALGFKLLGFDEDKNIPECESLAPHLPPQWNSGFGSYSFVYKHKQSAMTFSIRIDRMGKKVEVRGVAVGDDNIRRFERSISDVVDSRKLPLRITIKDGQEDRGDLPEKLRGVFASEQAIADILHDLKVNIVQKLIPKLQSEGYVETAEAEANARSERRAQEAQNPDRPFRGDPVPHPHPLQPPANPLPEMARPRPAPVGDFPPPGFEDEYEMNRPPRGGLQMPGRSPYNIGHDDLNPPGLGPHDPLRGSFIGGGLPRPGGGSGMHPTFDDPLFGGQGGDGSSGFDPQAPPGARWDPTGPGGNPRFPGPGSGRGNNPFGGGYGGGFGGGFGGDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNH8</accession>
    <name>X0CNH8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNH8"/>
    <dbReference type="HOGENOM" id="CLU_139274_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="154" mass="16882" checksum="A75D3C04CFFE7C95" modified="2014-05-14" version="1">MHKVKNLGNVTGGLQQDGSRDEKAIETMACLHSMRPSRMEDIMNTGGGDALVLDERGAERPKSSSSLRIDMIKTEEGERKSTGPCRSQKVRVPAKFGGLLWATVHVWVEARRAFVGAFEAASWGCYAVHPRDHSSVSWGDDDEVVRVASPSRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNN9</accession>
    <name>X0CNN9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNN9"/>
    <dbReference type="HOGENOM" id="CLU_1643778_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK96065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="161" mass="18334" checksum="F292295C4394BA77" modified="2014-05-14" version="1">MLRPTPLSTNPTRSTSAVTNTPERLHHVVQNQTAARTNQLASCTIARPRAAIRNTKTSNGSRDTLLKNQFVCGTCKEEFHSRDDLVSHIDETEECSSEDTPIEHFCVECNKLFNEAKKLDDHNKRQHSWIPNVCDWSDCEDRTVFELNLHTSLIESSIKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPA1</accession>
    <name>X0CPA1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Thiol-specific monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_03358</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FMO family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPA1"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006909_5_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000138">
        <property type="entry name" value="Flavin-containing monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK96255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="54910" checksum="866185E0A111049B" modified="2014-05-14" version="1">MALADKLDVRRIAIIGAGPSGLAAARYLLAEKTFSKIRVFEQRATPGGVWNYTPLAREQGFSVPRTQPSFTPDQALWPNDNGDVEFMSPIYDLLETNIPHSLMRYSDKEFPQGSSLFPRHSVVLQYLKEYAQEINPHISYQTQVLNIEKPDPSRSQPWTVEVLDLKANKVIKDEYDAVVVASGHYNDPFIPDIPGLVDFDKAYPGAISHSKFYRRPNDFKDKKVIVVGNSASGVDVSAQLSTVAKQPIFVSEKEKPTVIPPAKEPWAAGVPEIVEFLPSQRGVRFANGQIENDIDAVIFCTGFHYSYPFLKSLDPTVVVPSGGHAAHLWEQILYTADPTLSFLSVPQRIVPFPIAEAQSALIARIWSGRLNPPSEAAMEAWVQEQHAKKGEGKAIHVMAFPEDVDYINRLYELSKTATKAPELGLENDGEGKRPPYWGLDKRWVRERVPKIKLASRAAGDKRHELRTLEDLGFDYEEWKRTVEEGEKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPI4</accession>
    <name>X0CPI4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell cycle arrest protein BUB3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05769</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPI4"/>
    <dbReference type="eggNOG" id="KOG1036">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038526_0_0_1"/>
    <dbReference type="OrthoDB" id="10262475at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="97"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="255"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK92734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="348" mass="37248" checksum="372F1F8916C0BCBA" modified="2014-05-14" version="1">MAPATQYELSPPPTDAVSAIAFAPSSGTKLLVSSWDKKVYCYDIAGGAGEATLVNTYEHRAPVLDVCFGANDNEAFTAGVDWCVNKIDLETGEKTLLSKHAAPVRSIAYSPKFSILVSASWDCSLNLHNLSDPSSTPIRVSLPGKPHALAASPTKIVVAMAGRVINIYDLKTIVDLFATGSSDLQPWQQRESSLRYLTRAVSCMPNDAGYATSSIEGRVAVEWFEDTAESQARKYAFKCHRQAAPDGDGDIVYPVNALAFHPVHGTFASGGGDGTAALWDAEAKRRLKQYQKFPNSVAALAFSSDGRYLAVGVCPGFETGQEDYSGARQTSVLIRELGENEAKGKGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQM0</accession>
    <name>X0CQM0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQM0"/>
    <dbReference type="eggNOG" id="ENOG502RR0K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2038270_0_0_1"/>
    <dbReference type="OrthoDB" id="125347at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="122" mass="13181" checksum="41EEEA372E771FC6" modified="2014-05-14" version="1">MTIARQSLSSFRRIATVTSALRSQPVLSSYTSIRMNSGKVETPVSSDPNHDKNNPPVADHSDGAMASLKGAPGKRDASSFEDKNMTEKEKNTNSQNAQEQDGREGSTGEAGHFKKSGRKPKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR53</accession>
    <name>X0CR53_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_10942</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR53"/>
    <dbReference type="HOGENOM" id="CLU_053359_1_3_1"/>
    <dbReference type="OrthoDB" id="199599at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF1">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="7">
        <location>
            <begin position="83"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK84987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="206" mass="23116" checksum="3A5A8F91771683B3" modified="2014-05-14" version="1">MLRSRSNSEYSLQDLSNRPPSRRPSQTSDGNNSDTRPRNSNTSARGDASAAPQKEEEKKKKRSRLGRFWREYVSCEVDFSASRDHLANERTFLGYLRTSVAMSMVGTLVAQLFSLQHEGQHQAFGYFVTGKPLAMTCYSFSIGTIILGAVRTWRHQRTMMSGKALVGGFELHLLGLCSMLLLLVFFSFLLTIDVVKDKEPEPTATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRF2</accession>
    <name>X0CRF2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02137</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the GSE complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRF2"/>
    <dbReference type="eggNOG" id="KOG3886">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044099_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11384">
        <property type="entry name" value="RagA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002028">
        <property type="entry name" value="Related to GTR1-GTP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039397">
        <property type="entry name" value="RagA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF1">
        <property type="entry name" value="RAS-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK96706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="356" mass="39969" checksum="14123B5016FAE4BE" modified="2014-05-14" version="1">MASYIDTSLSEVQPAPELLGEVKKPKKKKVLLMGKSGSGKSSMRSIIFSNYIARDTRRLGATIDIDLSHVKFLGNLTLNLWDCGGQEAFMENYLSQQRVHVFSNVGVLIYVFDIESRDVDRDLATYVSILSALLQYSPAAKIYILIHKMDLVVPTARESVYDERIRVVRQKTFEYANSVGIAASSIELTPFATSIWDQSLYKAWASIIHDLVPNLSVIERNLANLGLAIEAEELLLFERTSFLAVSSWTSSEGQRNPTEDRLERMSNIMKHFKQSISRFTGTPRNAEQFIRMEHKAGNRFSLFILKFTTNTYLMVVLPPGEARFNAAMLNCQIAIEHFRFLDGPATPAPNTATAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSS5</accession>
    <name>X0CSS5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10363</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSS5"/>
    <dbReference type="HOGENOM" id="CLU_1367050_0_0_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF49">
        <property type="entry name" value="LYSINE BIOSYNTHESIS REGULATORY PROTEIN LYS14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936587" evidence="3">
        <location>
            <begin position="21"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="246" mass="28223" checksum="8F3B558340A6E875" modified="2014-05-14" version="1">MPKLTSDFLIAWFLYYDVLANFTQPAQKNSITEEQYLVRMLDISKIDTSAIVGSLGCSVELFEAIHHINHLHAFCKGHIPWLVTSTVLQRRIELGSQLRHLVQHLDPDEEKIATAPRRTQALATAELYRLAALLYLQRIYPIHEDDGSRITHLEEGFCALETLSVASSPWPVFILACESQTETQRITILRRLDDMESMRGIGNILVMRDIIEKVWKQNDLRQTTNPGEQFSWCQFVESGNAVPWFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSY7</accession>
    <name>X0CSY7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA ligase</fullName>
            <ecNumber evidence="7">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_02722</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSY7"/>
    <dbReference type="eggNOG" id="KOG0967">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005138_1_1_1"/>
    <dbReference type="OrthoDB" id="206088at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07900">
        <property type="entry name" value="Adenylation_DNA_ligase_I_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07969">
        <property type="entry name" value="OBF_DNA_ligase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3260.10:FF:000004">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000062">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.30:FF:000018">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050191">
        <property type="entry name" value="ATP-dep_DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674">
        <property type="entry name" value="DNA LIGASE 1/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674:SF9">
        <property type="entry name" value="DNA LIGASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 7 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="10">
        <location>
            <begin position="544"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="635"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="857"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="653"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="664"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="870"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK97565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="880" mass="97909" checksum="B9F38F6A62B97F89" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT41</accession>
    <name>X0CT41_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_04540</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT41"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="OrthoDB" id="2351791at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="498"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="36"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK94488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="564" mass="61309" checksum="D3AD06981CA54A81" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT53</accession>
    <name>X0CT53_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT53"/>
    <dbReference type="HOGENOM" id="CLU_061850_0_2_1"/>
    <dbReference type="OrthoDB" id="3431997at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="221" mass="24582" checksum="3716D246161F051A" modified="2014-05-14" version="1">MGNASSKDSTLTPHISQETAAKGIPHNLSASFTKRASLTLQCILADPASKRDFAIHVPPNGSYDVIIYDGPDATSPVLAAAKGNPKWKHDFRINLPGLLEGDDTREELLRCTTINKLKEGYWFAMQLEGHLERFEWRLTRTKQVQGQEASGWGWKLVRVGLKIEPHDDGEEIVAIFTTHKSLGLKKIGDLAFTGSGITADFGRQWEIMVLTTWACVWSQHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUI0</accession>
    <name>X0CUI0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUI0"/>
    <dbReference type="eggNOG" id="KOG2551">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051938_2_0_1"/>
    <dbReference type="OrthoDB" id="2094269at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="51"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK94534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="296" mass="32390" checksum="161B9CFDB6100716" modified="2014-05-14" version="1">MRFLLGFFSAARPTVTTTRRASTFAFSSYKVCLSTMTATAATKPNGNGGKKEVKILMLHGYTQSGALFRAKTRALEKTLVKLLNPISLLPVFLYATGPNRLSPEDIPGYQPPEEPQPEDYQPDTWAWFRKDEATGNYRLFDEGMATVGLAIREAEGIDAVCGFSQGGAMAALVAAALEPERTLPEGKEGEWARGLREANSGKALKFVISYSGFWATPDSLQFCYEPKIKTPSLHFLGSLDTVVDESRSRALTDRCQDPLVLVHPGGHHVPVSKQWAAPLAGFIKEHGQNNEPKAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUT9</accession>
    <name>X0CUT9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">2-dehydropantoate 2-reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_01179</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUT9"/>
    <dbReference type="eggNOG" id="ENOG502QPT5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031468_3_0_1"/>
    <dbReference type="OrthoDB" id="73846at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050838">
        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="5">
        <location>
            <begin position="145"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="6">
        <location>
            <begin position="305"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="31"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK98200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="465" mass="52695" checksum="AF740817124A5113" modified="2014-05-14" version="1">MQPRATAQIARKSTRWLRNSPNFGYTRLFASAVPPTEQKKPEAVPPELGSAPSRPWQSSSIQAGSVTPTSTSPSSQFYVPSVVIPAEAAKSGPVHKIHILGEDVRSRFIAHALCSVYDSVETVPFREMPKSRYRNVEKVQPERTRKNAYVEKNAAMPEDDVVPQSDRSHIDELIVTGRGFEAVKAIVSVKDRIDDKTSICLLNDGMGVLERVREEIFDGTQPEPNFYLGHMSHALGFNRNRDSVKQFKSGRTVFTKADPVLNAEKELYIPAEQQPSMMHSLRRVKELNTTFSTYEHWLRFKLPSIMFTAAVEPVCVLLDLPYQGLLENRNAQKMMNQLLGEMALVTENMPEVQDSPDLIKFLRGEGLKKFCYRRITGKSNAPSDLLTRINKGLQTDINYQNGYFLKRARILGIDTPTNQLMVQMIKARRIEQQQKLRSIIPVQEASPNDVRKKTQRRMLKNGLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUU9</accession>
    <name>X0CUU9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUU9"/>
    <dbReference type="HOGENOM" id="CLU_1402553_0_0_1"/>
    <dbReference type="OrthoDB" id="5072679at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="181" mass="20309" checksum="BB2371AFF44A6365" modified="2014-05-14" version="1">MDLFITAQEPFAHHPLKAKSFPSALSNATDKTSGDARPLVSLPPVSQLEFDLIVHDPCHDSTLTGSWDPLPTPLSIPLNTSRVHLLNLLREKLPVVEASSKNRLSRQTYGGKIYPLGPSDKEWHYRDLVTKTDIMARSELEWFLLKEMMASSRGALKCYISVRGEHVPAKKTSGWWFKNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV83</accession>
    <name>X0CV83_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_01306</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV83"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_2_0_1"/>
    <dbReference type="OrthoDB" id="1935484at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000247">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000106">
        <property type="entry name" value="MFS transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF60">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17160)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="70"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK98375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="533" mass="60235" checksum="B7286ADE89BB8425" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWB5</accession>
    <name>X0CWB5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AP-1 complex subunit mu-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_04143</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWB5"/>
    <dbReference type="eggNOG" id="KOG0937">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030665">
        <property type="term" value="C:clathrin-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09250">
        <property type="entry name" value="AP-1_Mu1_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14835">
        <property type="entry name" value="AP1_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000006">
        <property type="entry name" value="AP-1 complex subunit mu-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="8">
        <location>
            <begin position="167"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK95593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="448" mass="50590" checksum="8CA41B90290DA2E4" modified="2014-05-14" version="1">MASALFFLDLKGKTLLARNYRGDIPMSAVEKFPVLLSEAEEDSSAVPPCFSHEGINYLYIRHNNLYLLALTKRNTNAAEILLFLHKIVEVFTEYFKALEEESIRDNFVIIYELLDEMMDFGYPQTTESKILQEYITQESHKLEIQARPPIAVTNAVSWRSEGIRYRKNEVFLDVVESLNLLVSANGNVLRSEILGAIKMKCYLSGMPELRLGLNDKVMFETTGRATRGKAIEMEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTQVKPLIWVECVVESHSGSRIEYMLKARAQFKRRSTANNVEIVVPVPDDADSPRFRTNIGSVHYAPEQSAIVWKIKQFGGGKEFLMRAELGLPSVRGDDEQGGGMMGGFGGSMGGVGGVGKGAKRPIQVKFEIPYFTTSGIQVRYLKITEPKLQYPSLPWVRYITQSGDIAVRLPDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CX66</accession>
    <name>X0CX66_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_03130</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PGA52 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CX66"/>
    <dbReference type="eggNOG" id="ENOG502QSI7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030276_0_0_1"/>
    <dbReference type="OrthoDB" id="118256at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018805">
        <property type="entry name" value="YJL171C/Tos1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018807">
        <property type="entry name" value="YJL171C/Tos1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737:SF2">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10287">
        <property type="entry name" value="YJL171C_Tos1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10290">
        <property type="entry name" value="YJL171C_Tos1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938019" description="glucan endo-1,3-beta-D-glucosidase" evidence="9">
        <location>
            <begin position="18"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 N-terminal" evidence="11">
        <location>
            <begin position="39"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 C-terminal" evidence="10">
        <location>
            <begin position="222"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="115"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK95883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="462" mass="50240" checksum="6D7B7203486123C3" modified="2014-05-14" version="1">MKVTNLSILAYTGLTTALTQQCSGSAVNEGGNWFCGVIDQILYEGFSSSGSFKAVTKMGDDGSCDQEPFSYDGALGPLSEDLSVHIRGPFNLKEFAVYNLGSSEKKRDSAPSPHLHGHRHFHEQRKKKRGDWVTATIDGQVVSWENTYNGSPATQAAPVDIPAAPTDAVNVVDEKKPMKLKADPLPGLDKIKSKVENAKGKVDQVKSKATSKAKEYTATPGGHWKRTAYYNAQRRVADNVIFMGNYGGEGSGVFDNTWGNSLSYLNANGNGGSSSPKILKDVFIPSNKEFSIFSSEKCDESCGYSRVPDVAYKGFSGSNKIFLFNFKMPFDGNTGFNGDMPALWALNGRIPRTGQYSGCSCWKTGCGEVDIYEVLATGDDKCKSTFHLTNGAGSSDYFKRPADKYIKVAVVFCERTSSVAIKQLDDTFDFGSSLSDETVRDWIKTMSTPKKGSSLFQLSISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYM5</accession>
    <name>X0CYM5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYM5"/>
    <dbReference type="HOGENOM" id="CLU_2096960_0_0_1"/>
    <dbReference type="OrthoDB" id="10337213at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="116" mass="13060" checksum="84BC18A416D5FFE9" modified="2014-05-14" version="1">MIKSRRFAQAAWLGSQVETPWGILGWPVKLGRVDEQHEKIRTESVRYAKVVNLKIPWEISLRRRSKPPVARTHHQSTTTDHGPTPGLGGHQGSGMMDPRHSSICTLGVRESVRKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYN9</accession>
    <name>X0CYN9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYN9"/>
    <dbReference type="HOGENOM" id="CLU_146832_0_0_1"/>
    <dbReference type="OrthoDB" id="5226533at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="91" mass="9918" checksum="E5A6A1C6B86DA241" modified="2014-05-14" version="1">MSALPPQKFLPLTPAPKSSFLSLAPATSPSYPQKPAVRSHTRPSPPRRASTESSSSSSSSNNSYRILKLGPVHYGEHADEHKTDFHDVILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0Y8</accession>
    <name>X0D0Y8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_00631</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0Y8"/>
    <dbReference type="eggNOG" id="KOG2190">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022670_4_2_1"/>
    <dbReference type="OrthoDB" id="1937934at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22455">
        <property type="entry name" value="KH-I_Rnc1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22456">
        <property type="entry name" value="KH-I_Rnc1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22457">
        <property type="entry name" value="KH-I_Rnc1_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049786">
        <property type="entry name" value="Rnc1_KH-I_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="45"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="131"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="288"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="220"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXL00456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="372" mass="39620" checksum="385DD3CBF118C74C" modified="2014-05-14" version="1">MSAPQDSIPGNGSDILDQMDQLRMDDRLGPDGEPAPKTDEEYAQAQLTLRAIVSSKEAGVIIGKGGKNVADLRDETGVKAGVSKVVQGVHDRVLTITGGCDAISRAYAIVARALLEGAPAMGMGGVVQSNGTHPIKLLISHNQMGTIIGRQGLKIKHIQDASGVRMVAQKEMLPQSTERIVEVQGTPEGIQRAIWEICKCLVDDWQRGTGTVLYNPVVRTQPSGSGNASGGAGFSQGSGRSDYGGSPRVMRTGNGADFSNGNSRPYNRRSDSDAALRGPPTHDENGEEIQTQNISIPADMVGCIIGRAGSKISEIRKTSGARISIAKAPHDETGERMFTIMGTAKANESALFLLYENLEAEKMRRSQLQEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1Y8</accession>
    <name>X0D1Y8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Large ribosomal subunit protein mL59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1Y8"/>
    <dbReference type="HOGENOM" id="CLU_1235059_0_0_1"/>
    <dbReference type="OrthoDB" id="18529at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037507">
        <property type="entry name" value="Ribosomal_mL59"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040922">
        <property type="entry name" value="Ribosomal_mL59_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18126">
        <property type="entry name" value="Mitoc_mL59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL59" evidence="1">
        <location>
            <begin position="17"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="224" mass="25900" checksum="B23527FC2BDF49D4" modified="2014-05-14" version="1">MASTSQFIGLAKSLPAPLQRFFARYPPAAILPENTPKTRYQEERPNPFRFYKHPVTGKWQDPVYSQRRQAELVKMARENGVEDLLPETRKGTEYKLAHRVEHGLRVKGTGVGQKVKGHIHERHMIAKMETRRKAMLDMPSLIKRWKRVRSKIDCLDRPREHVLLTTLTGGQIRLDQVPQINKKKRDGMTALARPVHSPCIFMYNNISDRLVKERLCTQDPASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3D6</accession>
    <name>X0D3D6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF167 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0235 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3D6"/>
    <dbReference type="eggNOG" id="KOG3276">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130694_1_0_1"/>
    <dbReference type="OrthoDB" id="244097at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="entry name" value="YggU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00634">
        <property type="entry name" value="UPF0235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00251">
        <property type="entry name" value="DUF167 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13420">
        <property type="entry name" value="UPF0235 PROTEIN C15ORF40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13420:SF7">
        <property type="entry name" value="UPF0235 PROTEIN C15ORF40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="YggU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="12284" checksum="7232E8CA3ED1B435" modified="2014-05-14" version="1">MASSSAIRFVTGTKKSPLGSVHLQLRVKPGASKNREGVIAVADDAIELCVSAQAREGEANKAVVQVLSGILGVPKSSLQLTHGMKSRDKTIVLGGIKGDGEDYARSIREILDKAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5K5</accession>
    <name>X0D5K5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein N-terminal and lysine N-methyltransferase EFM7</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFM7</name>
        <name evidence="6" type="ORF">FOQG_01600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5K5"/>
    <dbReference type="eggNOG" id="KOG2920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032409_0_0_1"/>
    <dbReference type="OrthoDB" id="46564at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071885">
        <property type="term" value="F:N-terminal protein N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03223">
        <property type="entry name" value="Methyltr_EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025784">
        <property type="entry name" value="EFM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF10">
        <property type="entry name" value="PROTEIN N-TERMINAL AND LYSINE N-METHYLTRANSFERASE EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51560">
        <property type="entry name" value="SAM_MT_NNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="81"/>
            <end position="83"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK98848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="265" mass="29656" checksum="7AAD5F9E41182DB2" modified="2014-05-14" version="1">MSGEVDYGFGDLMDDPEDYCPPTPPPTSQVFTMQGGKPITLHLVGASPTEAHHLWNGAKMISDFFEEDPSRVREKTVLELGAAAGLPSLVAAILGARKVVVTDYPDPDIVRIMQKNIDECDETVEPRGRIASTVDAVGFVWGADPIPLLTRLNPTDDSHEERFDVLILADLLFRHSEHGNMVKSIKETLKVSRESVAYVFFTSYRPWKKELDEGFFDIARDQGFEVEQIAERRLDKPLFENDPGDLDVQKTVKGYAVRWSAEKCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D655</accession>
    <name>X0D655_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chromatin structure-remodeling complex subunit rsc7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07491</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D655"/>
    <dbReference type="HOGENOM" id="CLU_022149_0_0_1"/>
    <dbReference type="OrthoDB" id="5598844at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013933">
        <property type="entry name" value="CRC_Rsc7/Swp82"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF3">
        <property type="entry name" value="CHROMATIN STRUCTURE-REMODELING COMPLEX SUBUNIT RSC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08624">
        <property type="entry name" value="CRC_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK90122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="57485" checksum="0889C3B433EA62D9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8C3</accession>
    <name>X0D8C3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar-sorting protein SNF7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Vacuolar protein-sorting-associated protein 32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06989</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF7 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8C3"/>
    <dbReference type="eggNOG" id="KOG1656">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071097_1_0_1"/>
    <dbReference type="OrthoDB" id="5592979at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000815">
        <property type="term" value="C:ESCRT III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF10">
        <property type="entry name" value="GH13992P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="181"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK90867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="223" mass="24812" checksum="A509611D29B98861" modified="2014-05-14" version="1">MWGWFGGAAAQKRKDTPKNAILGLRAQLDMLQKRERHLQTQIDEQDATARKNVSTNKNAAKAALRRKKTHEHALEQTVAQIGTLEQQINSIESANINKETLAAMSNANAAMKQIYGGLTVDKVDATMDELREHNAMSDEIVNAITSNSLGEPIDEDELENELDELQQEQLDEQMLKTGTVPVSDAVHKLPTPAREEPVSSKKQAVEEDDEEAELRKLQAEMAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8M5</accession>
    <name>X0D8M5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502S6DU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_241636_0_0_1"/>
    <dbReference type="OrthoDB" id="3647690at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038609">
        <property type="entry name" value="HDA1_su2/3_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="485"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="603"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="703"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1547"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1336"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1480"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="513"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="703"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="755"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1547"/>
            <end position="1558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1608" mass="178612" checksum="9B4F3D7EEDD94F49" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9Q2</accession>
    <name>X0D9Q2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_06723</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9Q2"/>
    <dbReference type="eggNOG" id="KOG2164">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011811_1_0_1"/>
    <dbReference type="OrthoDB" id="302966at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16536">
        <property type="entry name" value="RING-HC_RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039739">
        <property type="entry name" value="MAG2/RNF10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983">
        <property type="entry name" value="RING FINGER 10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="185"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="499"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="604"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK91312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="644" mass="71244" checksum="AEEEC261CDFA9B64" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0DB55</accession>
    <name>X0DB55_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoporin NSP1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Nuclear pore protein NSP1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Nucleoskeletal-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_00787</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Nucleoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the nucleoporin NSP1/NUP62 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DB55"/>
    <dbReference type="eggNOG" id="KOG2196">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018823_0_0_1"/>
    <dbReference type="OrthoDB" id="344345at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044613">
        <property type="term" value="C:nuclear pore central transport channel"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000040">
        <property type="entry name" value="Nuclear pore glycoprotein p62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026010">
        <property type="entry name" value="NSP1/NUP62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007758">
        <property type="entry name" value="Nucleoporin_NSP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12084:SF0">
        <property type="entry name" value="NUCLEAR PORE GLYCOPROTEIN P62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12084">
        <property type="entry name" value="NUCLEAR PORE GLYCOPROTEIN P62-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05064">
        <property type="entry name" value="Nsp1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin NSP1-like C-terminal" evidence="16">
        <location>
            <begin position="494"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="384"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="557"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="166"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="314"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="384"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="408"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="491"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00078941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00081079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXL00779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="716" mass="69353" checksum="FB818B63974B648D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBH3</accession>
    <name>X0DBH3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-(Hydroxymethyl)glutathione dehydrogenase/alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBH3"/>
    <dbReference type="eggNOG" id="KOG0024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_3_1"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08283">
        <property type="entry name" value="FDH_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF1">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="5">
        <location>
            <begin position="64"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK91917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="453" mass="49727" checksum="0C19EF702756B5E6" modified="2014-05-14" version="1">MATQAAYQAEKVIGHGDNAVTAQDVTSYREPGAGESGETMKALAWISKNKVQMVDAPKPKIIEDRDVILKVTGSTVCGSDLHLLHGTVVQLSEGDILGHEFCGVVDQVGSAVKGIDVGKRYVASFQIACGDCFFCKQKLSSQCEKTNSNTTERAMYGGRTAGMFGYSHFTGGFAGGQAEYVRVPLGDVNLLEIPDDVPDEKALYLSDVLATSYNAVKDTAVYPDDSVAIFGAGPIGQMAGVFAIKEGASQIIFVDTEPRLSFIRDHWPAEHKDKLELVDYKHLSHGVTNKPTVVSRLKELTGNRGPDCAIECAAGEYAKGWMHWLEMAVGIETDTSEIINEMIEGVRNFGRCGVTGVYVGYTNHFNIGSLMERGIRLIGNGQAPVHKYWHELLEMIQKGELDPGQMLSHRVRLEDLDKVYYKFEKREDGMQKIFVETKFSFPQDPSTPSLTTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBS9</accession>
    <name>X0DBS9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pinin/SDK/MemA protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_00894</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pinin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBS9"/>
    <dbReference type="eggNOG" id="KOG3756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="330772at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039853">
        <property type="entry name" value="Pinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006786">
        <property type="entry name" value="Pinin_SDK_MemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707:SF0">
        <property type="entry name" value="PININ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707">
        <property type="entry name" value="PINN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04696">
        <property type="entry name" value="Pinin_SDK_memA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Pinin/SDK/MemA protein" evidence="10">
        <location>
            <begin position="92"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="218"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="115"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXL01004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="293" mass="34262" checksum="4CBF4E0E6CE50774" modified="2014-05-14" version="1">METRNELRPLDDTKADHEQHNDTLSEDVPNKDSMKRKASINADELSSKRTKHDDYFREAPSEPRKRNSSPNRHNSYGDSPDIDVDRRKNATQEEKRRGKRLFGGLLSTLSQTGGSVQQKRRLEIERRQQDRLQKQNIEEDRLREEKRLRLTEVRRGEQLTFDEEVMHSKHTKMLAMARYLRTKSRPHIYYLPWKLTAEQEDTIDDQIQQTKVTIEREVESLNARKGRQAKGGRQPSETTAPSRQELDHDSKDTNGPEKSPHGQEKPLQASNHDHHHDESADVLEEADEDMVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0DEK3</accession>
    <name>X0DEK3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05199</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CbxX/CfxQ family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DEK3"/>
    <dbReference type="eggNOG" id="KOG0730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2423195at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000216">
        <property type="entry name" value="Type VII secretion ATPase EccA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041627">
        <property type="entry name" value="AAA_lid_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000641">
        <property type="entry name" value="CbxX/CfxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050773">
        <property type="entry name" value="CbxX/CfxQ_RuBisCO_ESX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN / ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392:SF2">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN _ ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17866">
        <property type="entry name" value="AAA_lid_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00819">
        <property type="entry name" value="CBXCFQXSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="226"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="502"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="785"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK92952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1046" mass="116669" checksum="A21513DFE2BC3209" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>X0DRL5</accession>
    <name>X0DRL5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_02312</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000003">
        <property type="entry name" value="Histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.40:FF:000044">
        <property type="entry name" value="Putative sensor histidine kinase/response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000285">
        <property type="entry name" value="Putative sensor histidine kinase/response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000579">
        <property type="entry name" value="Sensor histidine kinase/response regulator, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF46">
        <property type="entry name" value="HISTIDINE KINASE_RESPONSE REGULATOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 13" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="114"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="16">
        <location>
            <begin position="1947"/>
            <end position="2172"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="17">
        <location>
            <begin position="2221"/>
            <end position="2345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="512"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="702"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2347"/>
            <end position="2399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2424"/>
            <end position="2564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="512"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="541"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="726"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="2362"/>
            <end position="2380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="2381"/>
            <end position="2395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="2467"/>
            <end position="2481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="2482"/>
            <end position="2491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="2547"/>
            <end position="2556"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="13">
        <location>
            <position position="2276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK96922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="2564" mass="283996" checksum="BEEC9F81B306E5AD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0DSY5</accession>
    <name>X0DSY5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein MAK16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_02586</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the MAK16 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DSY5"/>
    <dbReference type="eggNOG" id="KOG3064">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050888_0_1_1"/>
    <dbReference type="OrthoDB" id="10251342at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.110:FF:000001">
        <property type="entry name" value="Protein MAK16 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006958">
        <property type="entry name" value="Mak16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405">
        <property type="entry name" value="MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405:SF4">
        <property type="entry name" value="PROTEIN MAK16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04874">
        <property type="entry name" value="Mak16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003352">
        <property type="entry name" value="MAK16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="6">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="200"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="200"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="239"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR003352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK97367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="312" mass="36691" checksum="5B4F4493491F99F7" modified="2014-05-14" version="1">MSSDEIVWQIIGQQFCAFKIKTNKAQTFCRNEYNVTGLCNRQSCPLANSRYATVREDAGKLFLLVKTPERSHLPSKLWQRYKLPNNYSKALSTIDEKLIYWPNFLIHKCKQRLTRLTQVQTRMRRIAAEEERLGEKLVPKMAPKIRHREQARERKAEAAAKLERTIERELVERLRQGAYGDQPLNVSESIWKKVLNAMERDGEGQRDKDMDKGLDENGEEADWSEEEDDNLENQVEYVSDIEESDEELGDLEDWLDSENEEEDEDEDDDESEESETEKSGNKRKRGRAIKMKNKKPRQEEKEKLMLTNDLTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0DTB4</accession>
    <name>X0DTB4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type 1 phosphatases regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02672</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the YPI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DTB4"/>
    <dbReference type="eggNOG" id="KOG4102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098333_0_1_1"/>
    <dbReference type="OrthoDB" id="307488at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011107">
        <property type="entry name" value="PPI_Ypi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07491">
        <property type="entry name" value="PPI_Ypi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="10"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK97492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="156" mass="16796" checksum="7A7A693BE44E7A50" modified="2014-05-14" version="1">MSQRQQQRSAPAPSQTQTETPTQTPETREQAPQILRLRGAHASNGRSVQWAEDVVDNEGLGRKSSKVCCIYHKPKAVDESSDESSSDSDSDSDSGSDRDGAQPAGGKRQSCGHGHGHSHGRGRRNGKGKEKRAPSPNAYEKVPKPKPKDGPSENKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DVP6</accession>
    <name>X0DVP6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DVP6"/>
    <dbReference type="HOGENOM" id="CLU_3260565_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="42" mass="4667" checksum="E49D3C4709A8ED56" modified="2014-05-14" version="1">MLSVSLVLNFARLFADPHEYNAEEVVLPSWAPLSGQYQALCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DX71</accession>
    <name>X0DX71_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DX71"/>
    <dbReference type="HOGENOM" id="CLU_2197073_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="108" mass="12292" checksum="48B42EC49D269025" modified="2014-05-14" version="1">MPAIMTPIPSFPTPQPFSSKPFHLSPKTFPRLSQDFPTCPLWNDQFPISLLAKHTDARRLDPDIQGCSVCYRIRCFHVAFLYRLSVPSVDVFRKGKQDAPIRHLIALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0DYX6</accession>
    <name>X0DYX6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DYX6"/>
    <dbReference type="HOGENOM" id="CLU_2885885_0_0_1"/>
    <dbReference type="OrthoDB" id="5068513at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="63" mass="7055" checksum="65BBA6B40F26FB68" modified="2014-05-14" version="1">MWSSPEEGETDYYPWVGNGTMEAAQHIVAWATFALGAVHACQRMRDEFKDGVDSDWADEEDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0E0T5</accession>
    <name>X0E0T5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">CMGC/GSK protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_00316</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E0T5"/>
    <dbReference type="SMR" id="X0E0T5"/>
    <dbReference type="eggNOG" id="KOG0658">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="272141at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14137">
        <property type="entry name" value="STKc_GSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000055">
        <property type="entry name" value="Glycogen synthase kinase-3 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000009">
        <property type="entry name" value="Glycogen synthase kinase-3 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039192">
        <property type="entry name" value="STKc_GSK3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="35"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK99957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="394" mass="45097" checksum="821ADC28E2F41FE2" modified="2014-05-14" version="1">MSAHRPNAFNSLRMGEVIREKVQDGVTGETRDLQYTQCKIVGNGSFGVVFQTKLSPSGEDAAIKRVLQDKRFKNRELQIMRIVRHPNIVQLKAFYYSNGERKDEVYLNLVQEFVPETVYRASRFFNKMKTTMPILEVKLYIYQLFRALAYIHSQGICHRDIKPQNLLLDPNSGILKLCDFGSAKILVPNEPNVSYICSRYYRAPELIFGATNYTTKIDVWSTGCVMAELMLGQPLFPGESGIDQLVEIIKVLGTPTREQIRTMNPNYMEHKFPQIKPHPFNKVFRKADANAIDLIARLLEYTPTERQSAIDAMVHPFFDELRDPNTKLPDSRHGTGQLRELPALFDFTRHELSIAPSLNQKLVPAHIRPVLASQGLDIDHFTPLTEQEMMAKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0B0S1</accession>
    <name>X0B0S1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979930">
        <property type="protein sequence ID" value="EXK75680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B0S1"/>
    <dbReference type="HOGENOM" id="CLU_2015419_0_0_1"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="1">
        <location>
            <begin position="34"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="13800" checksum="9E1D98EF7FD7CA33" modified="2014-05-14" version="1">MAALVIAIQSMLSAAEPNALQLYQREPSKGDGKYANMVYFVNWGIYERDFQPQDLPASSITHVLYAFMNVQEDGTVFTGDTYADLEKHYEGDSSLTSTVTHDLWRLRFANASFMANAEPINPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1U7</accession>
    <name>X0B1U7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979911">
        <property type="protein sequence ID" value="EXK75696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1U7"/>
    <dbReference type="HOGENOM" id="CLU_2339121_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="98" mass="11032" checksum="8B082F26FF1E0134" modified="2014-05-14" version="1" fragment="single">QEFPNLQSIVEAFDNTYHTAIEIKVEDSIKISLFDCNVFLAAADGLRAISLKTFARGQAKELEKLPDELKKTKPESQALIDKDALERNVSWLLDVVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1V1</accession>
    <name>X0B1V1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979604">
        <property type="protein sequence ID" value="EXK76100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1V1"/>
    <dbReference type="HOGENOM" id="CLU_3377177_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="34" mass="3791" checksum="18E07D661E665ED7" modified="2014-05-14" version="1">MSVLGNRTGVDPCFRLSRLKAKGRLKREPFSAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2S5</accession>
    <name>X0B2S5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979512">
        <property type="protein sequence ID" value="EXK76425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2S5"/>
    <dbReference type="eggNOG" id="ENOG502RKRG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123991_0_0_1"/>
    <dbReference type="OrthoDB" id="4996552at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.270.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="188" mass="20925" checksum="758DC3559EF05F21" modified="2014-05-14" version="1">MVIIDIATVLDHQLKLISKVKDTLNAMTPRPSDEIRDKHRWYQCTVQNATQFNIVLEKSYFNAGKYLTVPESVGPYGQMTFTAYNDVSGTSTGLSFWAHLDESHRFHFAIGLDAPLMGGFKAGVVESDSAKTGLEIATRQGNSITSENRYKGKDNDGNDQVIEFHVATYPGMEMEVVITQLIVDSDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2Y8</accession>
    <name>X0B2Y8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979497">
        <property type="protein sequence ID" value="EXK76500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2Y8"/>
    <dbReference type="HOGENOM" id="CLU_177153_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="73" mass="7874" checksum="C97E123423AA784C" modified="2014-05-14" version="1">MAKAKVVKAKKKAELLGAIKDAKRKSKKHMAGAAAQGLSLAMCLRRLKTLALHTARQLFMAIVAPKIDYASVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3B2</accession>
    <name>X0B3B2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979569">
        <property type="protein sequence ID" value="EXK76211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3B2"/>
    <dbReference type="HOGENOM" id="CLU_028818_0_0_1"/>
    <dbReference type="OrthoDB" id="5086080at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF7">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="39035" checksum="D5A82AFA044F4838" modified="2014-05-14" version="1">MYNETQNSTAEARRLKKRELDRKAQRLARERAKSRIAQLESMVDNLRQDHSNAQIATLMDQLGKVTKERDNLLQVLDSLGTTIRRHLGDSTTGEPRSDTKSDPSQHANPAQSKPGERIVPITTPRSTSETSSSTILELTTNPHAPDPFTYDGWNYTVSNEPYPTTMAFHNSILPPTGNGFIPIQPLLPDIHTLPEVVDVIIPKASVLCPCSNPTSRGANFHDVKPNIWRAINEVLVKPTKLSAEEIAIEEYNAEDMPVRAVLEGWDSIERAGKMTSTWRKLRKADELCFTNCADTERLAAMRICHLLIMYHGDPTLERRATLPRWYWNRPSQALPHSYGIDFFVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6G7</accession>
    <name>X0B6G7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658617">
        <property type="protein sequence ID" value="EXK77356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6G7"/>
    <dbReference type="HOGENOM" id="CLU_033830_1_0_1"/>
    <dbReference type="OrthoDB" id="5420247at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42029">
        <property type="entry name" value="AN04G07800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42029:SF3">
        <property type="entry name" value="AN04G07800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="300" mass="34452" checksum="B26FC60FE76B1905" modified="2014-05-14" version="1">MSEHGARPSSPAKVALEAWSQGCMIGALIIMIGITFANMRRGVLLHKLILIELLLAMPNGFFTFFDPPTWGWYLSSTLKNKPFLSKRHNTIYIGTIILVQPYWVLEIYANFTYFNPPYSRLFVSTRPLEAVCRDPWWIFTALNLFWNIKYRYEFKPLEIVRVSPRFGLLLLSMTLSIIFITVDLFSVTPVIPIGYINPFWKFAFIFKCFTDTIVLDDFKTALDKLSRYKMEQNYPLPFSRPRSHIEAQPPGSSLVHFDVICPVESSRLVTVEHLEKADNSPVSCPPKAVRASDTGLVDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7T0</accession>
    <name>X0B7T0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CorA-like transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658538">
        <property type="protein sequence ID" value="EXK78170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7T0"/>
    <dbReference type="HOGENOM" id="CLU_029947_3_0_1"/>
    <dbReference type="OrthoDB" id="5145609at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058257">
        <property type="entry name" value="CorA-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26616">
        <property type="entry name" value="CorA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CorA-like transporter" evidence="1">
        <location>
            <begin position="150"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="433" mass="49011" checksum="43DF82C24FDDDC10" modified="2014-05-14" version="1">MYDSVFEKPPGRGEKYPVDTDCYAPMGQDRNFLDQKLSEQSLELFQISGGGIDVISQIQDRGKAPDPLETQTPDKMSRIEGIAKSASFRVDVIKPAFSWSQICVTELAFRNVLATLHVFTPFLHVVHTFGTKTSDKQRARNVVHCHKWPAHGFEFCYNIRYFELNGRKRGNPWSLRQTGMYQNCVLRKQSRWILLNYSTYIYDRVSEAFASANVPHCGASTLVPHLFLLSAATRSWNLYIEALRHKVMLIEQKTYLSGLDQAPLHEHSPLFSDIQELKRLSDTISMAFDVINGQKEISVRCGDLHTSLALGHSDCDIADTIRMLQADLQHYHEEMTSLSRTTAKAEQLISSILAIRASNKLQTATDITQMNISDLHLQSRYMSVDAQNLLQVTERGHRDAIIMKILAQMAVVFLPASLVAASLISQYEDGELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9D4</accession>
    <name>X0B9D4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658506">
        <property type="protein sequence ID" value="EXK78730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9D4"/>
    <dbReference type="eggNOG" id="ENOG502QT5J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_413899_0_0_1"/>
    <dbReference type="OrthoDB" id="5244761at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="663" mass="74578" checksum="3C2022A90449074E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9L1</accession>
    <name>X0B9L1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658500">
        <property type="protein sequence ID" value="EXK78830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9L1"/>
    <dbReference type="OrthoDB" id="5085151at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="309" mass="32325" checksum="E7DECFAC2B2AC235" modified="2014-05-14" version="1">MKVETPLYYALMLARLASGQNFSPECDDAGPVLYPGTWNQYLAPNMGVSCQKASILFSGQDTRQNLTIEHGDVLCYGFPLMNITIPINAPPGSGSIRFFCEGREAEYCQMISVETRPPDDAREASATEYAITQDCPVNPTLASEKYASASSKPTTVSTPTPKGVAPIGTAPTRAAMETPANQAPTNQTPTNQTPTNQTPTNQTPTKELSDTKIPETDADKPDPTGSGRSGSSDTDSATSTTNGDMPNETTLPLTGSHAAGSGAAQTTQSSEYTDIAAPALPESGNTHAPPSPSNEAQASGDNRPCTCGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BA32</accession>
    <name>X0BA32_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658512">
        <property type="protein sequence ID" value="EXK78631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BA32"/>
    <dbReference type="HOGENOM" id="CLU_2210191_0_0_1"/>
    <dbReference type="OrthoDB" id="10555894at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="102" mass="10933" checksum="684CAAF714C29E9E" modified="2014-05-14" version="1">MATINGTELRRSSRHSKTPRPSIERAESSQPDPKRRRSTGTEAPPSPAPTPNIPDEILVAPARNAVRGIEASAGDGIGEEVSEPSISPPLPWFAGMMSQYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB87</accession>
    <name>X0BB87_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658485">
        <property type="protein sequence ID" value="EXK79041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB87"/>
    <dbReference type="HOGENOM" id="CLU_767352_0_0_1"/>
    <dbReference type="OrthoDB" id="5213630at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="361" mass="41955" checksum="27A0CEE279715894" modified="2014-05-14" version="1">MDIDDCREEQRQKPNEVILEAQLADLKTQLQERDHKLKELEERCEMMSNGTLKKEQKLKELQDKCDNISKDADKKDQDVIKFRKLWKKAAMEHDKLRASGQGFYQMTDEYLVELINHLRLVIRDFSIQYFDGIALKKDFFTYRPSYIKHLERTTSDRDGFLWYMGSPTQSHEIIQAFLWRVIVSEIFNKFEWLGAETSAYLHLRDVLESSLYANSRGGPSLPNHEAERKFQTWSSTTTSMLLASVDLEKANNDMKRRTASHVTHIVNTVDNILRKDRERSFKDQLSAIITQASALDKEISRQVARVIWSFDITQREKEDQPCNPNKAGLVIAPAVFKRGKSTGEGFDQEIKLLDIVEGSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC56</accession>
    <name>X0BC56_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979608">
        <property type="protein sequence ID" value="EXK76089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC56"/>
    <dbReference type="HOGENOM" id="CLU_2346776_0_0_1"/>
    <dbReference type="OrthoDB" id="3596450at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="97" mass="11746" checksum="7B706D9E3CD18943" modified="2014-05-14" version="1">MIKRKQWVPSKEQVNRPAMDVFKMDRYRLVEVDYKDWRHLPREEATWEEISDNPDEDATHTFLPFVNFLQDLILLLIGRQALRQRTIQVRILACEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCI2</accession>
    <name>X0BCI2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_19071</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979578">
        <property type="protein sequence ID" value="EXK76169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCI2"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_5_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK76169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="257" mass="28431" checksum="346C727ED4DD1B6A" modified="2014-05-14" version="1">MKSCIHAAKQFEKLETRLDVVVANAALSVMPQTLTRDGLEIQFGTNHLGHFVFIYNLLDLIKETSKRYGDARVVVVASHAHAMYKAVPGDIIDFEDLRVERVTTLQTVADVQASLQRYARSKLANILFARALHKHLQESGQDNIFVNCLNPGTIGTSAATDSAAIPPWIAFLTSSVVRMTSIPVQDGARTTLLLTTDPEIASRELSGRYFDVGPLAGKFWYGYSWDATKAKLSAAARNDELGETLWKWSIDMMKTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCY0</accession>
    <name>X0BCY0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_18911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979531">
        <property type="protein sequence ID" value="EXK76344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCY0"/>
    <dbReference type="HOGENOM" id="CLU_018400_3_0_1"/>
    <dbReference type="OrthoDB" id="5282002at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="8"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK76344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="559" mass="63334" checksum="CDFC5B0B3C6BFB83" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFG6</accession>
    <name>X0BFG6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658591">
        <property type="protein sequence ID" value="EXK77583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFG6"/>
    <dbReference type="HOGENOM" id="CLU_746053_0_0_1"/>
    <dbReference type="OrthoDB" id="5109254at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="371" mass="42292" checksum="C33CD83CA61D3630" modified="2014-05-14" version="1">MDDLREAAESALKSLYVLPTNCPAKDFDDVIVYLTKSLALAKVLRAWSLGIKEGLSKNYRTKRMNNYFKLLCTLEEEANNTGKTSQRNTHKFSHNSSKEIPVLSHLINSVSYIREDARRIDPDMVDVMKDENMYTKFVPILSSHEDFREHAWSITTKKEFKTLHCREDSDQGQLASKRRRDEQDIPQKRAKQGIGSHPEAPTTEDTQACLQEHQTSQAGPLAVSSSVTQERELGSRRWQLSVIQSRAAILHLQQTLSLWLKTAVFARPYSRDRYFPSCLVFQTHQDVEFFRRLPKLDVDWKTIPKEAHRALKDSEESLKVVMGEINSVDEYAGLAFLPATASGEKPRIRLVFYQGIAITGVLAQLPDIPCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGI2</accession>
    <name>X0BGI2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_14292</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979335">
        <property type="protein sequence ID" value="EXK81240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGI2"/>
    <dbReference type="eggNOG" id="ENOG502SHEY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036824_1_0_1"/>
    <dbReference type="OrthoDB" id="4685598at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK81240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="599" mass="66932" checksum="AB7084A0EBD37B6E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHI2</accession>
    <name>X0BHI2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658529">
        <property type="protein sequence ID" value="EXK78308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHI2"/>
    <dbReference type="OrthoDB" id="5103904at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="238" mass="26683" checksum="97D1E4CF39F370BC" modified="2014-05-14" version="1">MMESQVMNRSPDHHGHQLGDGPGRTAGTHDKQPCRRTDHDISTSHRASEEEMNTVVEFQATVMNSFIADPAAWLRRERSYLKIDNSKRRLHEGQIASDASFGALSSDHTFASRLSSEDQRTEDADGNPISPAYTSSEPETCALLESRLTAERGNHYLALDDAASCLRMGYQEGELLKDLTRKQQVAGDCQERAFRYHSCEAHMGGCLERVNKKWLCVGRREGNHTSGIIRDYHFSKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI28</accession>
    <name>X0BI28_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bul1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658421">
        <property type="protein sequence ID" value="EXK81800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI28"/>
    <dbReference type="eggNOG" id="ENOG502QSAC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032323_1_0_1"/>
    <dbReference type="OrthoDB" id="2283785at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039634">
        <property type="entry name" value="Bul1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904:SF1">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="51310" checksum="79B9EA96EBFEDECC" modified="2014-05-14" version="1">MPSRYLLPSRAKQDPKLEINIDGHYESKIYTFGSAISGFVTITAHNQLPFQSLQIDLRGITSTCGHAFQYGTPFKTHTFMQLQMPISASALPISQSLEPGQLYHVPFRFVIPEQLSTTACNHQNTAVRERHLRPPPSMGVWDHDDLVGGSAHVDYVIRGRLVLSKNKRGEEQYLDQSRSIKVIPALPEQPPLHVRPESSDYCLSQTKTIRKGVIGTKMGLVRASATQPQPIVLCLDGLNATESQIPIDLEYIPASASTMPPDIRVKSVTIETFTNFWLGIDGYLPDHHEKPSNSVAPTAPWLTSHALVLKDRERVYWKKGHQPISEKGSERRFSEPAHIIRDCTEPQVIPRSASCASYCLDSSKTPGYKATIQQSFKLPTENSLFLPTFYSCLISRTYRIRVTLAIGTYGTTISLVVPLQIAANGLDDAQDNSQLRYMTQDIEYEQAEDVLPPYSRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI87</accession>
    <name>X0BI87_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI87"/>
    <dbReference type="eggNOG" id="ENOG502SJKY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084522_0_0_1"/>
    <dbReference type="OrthoDB" id="2446447at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02219">
        <property type="entry name" value="cupin_YjlB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047121">
        <property type="entry name" value="YjiB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36448">
        <property type="entry name" value="BLR7373 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36448:SF3">
        <property type="entry name" value="CUPIN TYPE-2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-1" evidence="1">
        <location>
            <begin position="67"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="236" mass="26224" checksum="FC30E07810A0877E" modified="2014-05-14" version="1">MVEVKQYHLLPTDLIPNSPRPLLHYKNVLAKRPNSSKCDPAEVWNMFTKNGWDVQWIFRYPNTQLSHFHSEAHECMAVLSGTATIRFGVGDTSEDLQENTYGSAWEKGGIVLEAEAGDVFVIPAGVAHKTHNTKPAAEFKLLSPGVGHGIEADDPKKALSEIKLDGYTMMGAYNGGEWDFVKSGGDYGKSWRVPKPKMDPVFGEAEEGLVKTWPGGDTKVDLEIVQVENREYKSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BID6</accession>
    <name>X0BID6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Enoyl-CoA hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_13694</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658419">
        <property type="protein sequence ID" value="EXK81935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BID6"/>
    <dbReference type="eggNOG" id="KOG0016">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_6_2_1"/>
    <dbReference type="OrthoDB" id="448450at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000048">
        <property type="entry name" value="3,2-trans-enoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK81935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="231" mass="25535" checksum="57B4007550ADD108" modified="2014-05-14" version="1">MAVIEVEYSGPIAVVVLNKPNELNALTKDEFYQLARTLQDVANHNEVVATVLTGNGRFFSAGADVSVSRQMPEGTDLYRHNLTVTVASNMNLARAFYTYPKILVVALNGPVVGMAAALIAFANFIYCTRETYILTPFASLGLKSEGVSSIAFAERMGISKANEALILAKRISSKELLEAGFVNQIFNCPAESFRSEALKEVKDRFHDVLNASSMLQIKKMIRYRSRRELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIP6</accession>
    <name>X0BIP6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_13571</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI979331">
        <property type="protein sequence ID" value="EXK82055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIP6"/>
    <dbReference type="HOGENOM" id="CLU_032825_0_0_1"/>
    <dbReference type="OrthoDB" id="2096480at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK82055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="642" mass="71985" checksum="BBDC523E652F4009" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJB9</accession>
    <name>X0BJB9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_13475</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJB9"/>
    <dbReference type="HOGENOM" id="CLU_028200_10_0_1"/>
    <dbReference type="OrthoDB" id="5273647at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF92">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="27"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK82235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="327" mass="37454" checksum="3D2779C78AF720A8" modified="2014-05-14" version="1">MPIDPSGPTVIATEWALISIATAVILARLYLRLVLQRRSLLASDVFMCAAWASAVATASFDIYFYRIGIFKPGTTFDLAGFEGTAEEAESFYKLYYFANYPFYVTFYLSKAALLAVYLQIFPVFMVKRRRFLWVVIVYVAMGFVVTILLLSLSCLPVWRNWTLSEQRCTVKSIKTNFEISWVLNISGDILIFILPWLVIPELTLRRRLRYSLYATFLLGLINIIFCVVRFAQIEQYGGDLVITISLVELWSFIDACIGLIIACLPSLRPFFNWREKIQYYGQSSGQDSKGDSSQNSRRPMISLDPEMLSQPSNVHLSEDMQRRFSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKZ7</accession>
    <name>X0BKZ7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658480">
        <property type="protein sequence ID" value="EXK79144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKZ7"/>
    <dbReference type="HOGENOM" id="CLU_497862_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="547" mass="62627" checksum="B12B1B55E927A769" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BL68</accession>
    <name>X0BL68_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658477">
        <property type="protein sequence ID" value="EXK79184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BL68"/>
    <dbReference type="HOGENOM" id="CLU_2558381_0_0_1"/>
    <dbReference type="OrthoDB" id="5098525at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="82" mass="9472" checksum="B706E62EA5EE9D9F" modified="2014-05-14" version="1">MLNSRKLSKLEEDTLLEFIVDLDSRGYPPRLSGVEQMANRLLDARDAPRVGTRWAMNFVKRQPLLKEFRRDTAFPDPALPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLI8</accession>
    <name>X0BLI8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658474">
        <property type="protein sequence ID" value="EXK79344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLI8"/>
    <dbReference type="HOGENOM" id="CLU_003093_0_1_1"/>
    <dbReference type="OrthoDB" id="4845846at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022698">
        <property type="entry name" value="OrsD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12013">
        <property type="entry name" value="OrsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="965"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="987"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1000" mass="113730" checksum="90C4961505D15566" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLJ4</accession>
    <name>X0BLJ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_12707</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Efflux pump involved in export of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties. Constitutes a self-protecting mechanism of the fungus against critical levels of FSA within the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658407">
        <property type="protein sequence ID" value="EXK83035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLJ4"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_11_6_1"/>
    <dbReference type="OrthoDB" id="446368at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF186">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="309"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="397"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="12">
        <location>
            <begin position="84"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00054466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK83035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="534" mass="58497" checksum="C8FB78229BCA3C05" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLT0</accession>
    <name>X0BLT0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">FOQG_12635</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">54005</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the SWR1 chromatin-remodeling complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0391">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_24_0_1"/>
    <dbReference type="OrthoDB" id="372624at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18003">
        <property type="entry name" value="DEXQc_SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000005">
        <property type="entry name" value="Photoperiod-independent early flowering 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000655">
        <property type="entry name" value="Protein PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0010">Activator</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSA" evidence="19">
        <location>
            <begin position="318"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="813"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="1365"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="441"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1584"/>
            <end position="1624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1658"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="450"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="562"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="627"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="668"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="715"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1595"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1667"/>
            <end position="1681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EXK83115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1681" mass="189556" checksum="FFC901AA74544793" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLV4</accession>
    <name>X0BLV4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLV4"/>
    <dbReference type="eggNOG" id="ENOG502SVYD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_880105_0_0_1"/>
    <dbReference type="OrthoDB" id="5075531at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="316" mass="34745" checksum="0AECEBC1EBAB6149" modified="2014-05-14" version="1">MPFSQNFASNMLRRRDDDETEDGWCEFATIEDQFLWPGEGKTWVRGQTQMVGWGAGRDINGTRGEGSTKVKMELRWWKGTYGPGPDDLKPIVIFDNKTFDYPSSDWKLWNPNCTDTYMNYTWTIPMDLDVGDSKFTMTVYDVTNRSDISMLQSNLFFINADNGTSIADSNASTSTPESSQETSASTGLATGAKAGIGAGIGVLALILLLAGFFLYRRKKRQTASIAPTDGFEKPELDAKSTGISEVDGSGISPHQAPDNAIYEAPGVLVHEAPTGKEQTVVEKMKAARQINEEPIEMPADSPTPSPKTSQDRLNRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM55</accession>
    <name>X0BM55_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Arsenical-resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_15475</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658453">
        <property type="protein sequence ID" value="EXK79988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM55"/>
    <dbReference type="HOGENOM" id="CLU_022869_0_0_1"/>
    <dbReference type="OrthoDB" id="187348at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015104">
        <property type="term" value="F:antimonite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000009">
        <property type="entry name" value="Arsenite transporter, ACR3 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057:SF1">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="ARSENITE EFFLUX TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0059">Arsenical resistance</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK79988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="392" mass="42911" checksum="6F318E2ADE1BDA43" modified="2014-05-14" version="1">MKNGLSSHEPKPSPPRASPDNGSTGQADQDPEATAATMSHDEQPQQHLSAFRGLGLLDRFLALWIFLAMAIGIILGNFVPETGPALQKGKFVGVSVPIAVGLLVMMYPILCKVRYESLHELFSHREMWKQICFSIFVNWIVAPFLMLALAWAFLPDKPELRTGLILVGLGRCIAMVLIWNGLAGGNDEYCAILVAINSILQMVLFAPMAVFFIRVISHESGTIDISYSVVATSVAVFLGIPLGAAVITRIILRKVAGPDWYQQTFLKFLAPLSLIGLLYTILVLFASQGRQVVHQIVSVVRVAAPLIVYFVLIFFVTLWISRLLGFRLSMVVTQSFTAASNNFELAIAVAVATFGPNSDQALASTVGPLIEVPVLVGLVYAVRWMANRWGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMJ0</accession>
    <name>X0BMJ0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fatty acyl-CoA reductase</fullName>
            <ecNumber evidence="1">1.2.1.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12267</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a long-chain fatty acyl-CoA + 2 NADPH + 2 H(+) = a long-chain primary fatty alcohol + 2 NADP(+) + CoA</text>
            <dbReference type="Rhea" id="RHEA:52716"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:77396"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="EC" id="1.2.1.84"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the fatty acyl-CoA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.84" evidence="1"/>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMJ0"/>
    <dbReference type="HOGENOM" id="CLU_024661_1_0_1"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102965">
        <property type="term" value="F:alcohol-forming long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080019">
        <property type="term" value="F:alcohol-forming very long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05236">
        <property type="entry name" value="FAR-N_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026055">
        <property type="entry name" value="FAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011:SF45">
        <property type="entry name" value="FATTY ACYL-COA REDUCTASE CG8306-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011">
        <property type="entry name" value="MALE STERILITY PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioester reductase (TE)" evidence="2">
        <location>
            <begin position="9"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="420" mass="46781" checksum="179D1533B20D8A38" modified="2014-05-14" version="1">MSSQKVVLVTGATGFLGKVVVEELLRLRATHDIQQVILLIRKKDSFNAKTRFAQQISSSPCFSLLPKSWVEYIQVMDADLACFRCGLGDNEYGQVCETVTHIIHTAACIKFDSEVSDAISSNIDSSRNVLSLAKDCDKLQQLVVTSTAYVTPPQEAPIYESLVDLPRPASRLINELKTGVVGKQQAIAATGHPNIYSLSKCLAEHLICETKGSLPVTIVRPSIICAALEHPMPGWIDSKAAFGGLVLGFGSGVLRVIDGRPDAKLDIVPVDVVAGYLIREAFRIRCEDIERPSTRIVFSVATKERSLTLGEACKLLERFFKESFRYIGPQGHVLQFYQFLHHYFPLHLYAVTNRLKGNMTREKAAKRSWRIVSGMNAVFSPYTNYTYDFRPLEPPASFDPDEYIRTVCSGVQRNLMQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMW6</accession>
    <name>X0BMW6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMW6"/>
    <dbReference type="eggNOG" id="KOG1270">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_1_0_1"/>
    <dbReference type="OrthoDB" id="3647at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF3">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="28795" checksum="CCB83011FFD8D24D" modified="2014-05-14" version="1">MGDKTNIISDEAKTLGEKNKEHFDQVAAEVFKHPWIQRLCNQISDELREQIDWIGIPERPEGNKMLDYACGNGVASRALAPYLSTVRGIDISSKMVEQYNMLAELSGFSTDKMRAIHGDLMNPEASPSPELSPPEFNDFDLIVMCMALHHVQDYAAMVQKLSERLRPGGVLLIIDLVASSESGCPEATMAKELSNHTMSKMGFTEMEVKTAFEKAGLEGWSWRWCSERSQVPEEIGGEQQGFFARGCKSVRGSEMKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNW0</accession>
    <name>X0BNW0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658451">
        <property type="protein sequence ID" value="EXK80144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNW0"/>
    <dbReference type="eggNOG" id="ENOG502SNN0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099166_0_0_1"/>
    <dbReference type="OrthoDB" id="2150604at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="215" mass="24033" checksum="CE1E7632B90D04C5" modified="2014-05-14" version="1">MPHFSFLGETSTSADTIIQMLNEDDQTQKDEMTKNWRDHKLQELNFVGTLGALLASCLSTTGSWPDVLPNGHNKPWSVRTMWFSGLVFALFSVVIAGVQSMRLHRLSAHPDGLSLIRNSLVRKRQSDNKSRPSWLQVYAWEFSLAFLVLAIFCMVIGLTILIWAGTKFGPSKAREDGWWDGNSKMAVTFTIVLGFASLILVLSQSALSKSNVIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPK3</accession>
    <name>X0BPK3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_11937</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPK3"/>
    <dbReference type="HOGENOM" id="CLU_011915_0_0_1"/>
    <dbReference type="OrthoDB" id="5376052at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF28">
        <property type="entry name" value="C6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK83776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="592" mass="66314" checksum="BDDBF2DF49B9AD5B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ06</accession>
    <name>X0BQ06_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14529</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK81003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ06"/>
    <dbReference type="HOGENOM" id="CLU_2346749_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="97" mass="9958" checksum="2692F212F5D0DE70" modified="2014-05-14" version="1">MTASQGAKTNGSYFVVLSAIVVVSEEAIDDDSVSPAEADENTVVGVTDSVSTERIVEDKTVEVAGSVVIELADDMSVLVVSASLELVVLIDVTELGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQY5</accession>
    <name>X0BQY5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQY5"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_5_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF274">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00440)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="26717" checksum="FD0B9DC7304EE53D" modified="2014-05-14" version="1">MVRVFITGSTDGIGQAAAKLLAEQGHQVVLHARNADRAASAKAAIPNAAAILVGNLSSIEETKKLAKDANNAGPFDVVVHNAGIGYGSTASREITSDKISAVFAVNTLAPYILTCLMDKPKSRLLFMSSDSHYSGDETLKNATQSHSYGNTKLHDTMLAKAFARRWTDIQVLSMHPGWVKTKMGGNSAPVQLSEPAKALASWVVGEGSLTKVTSGAFVTTSGESRPHPGADSVSKQEELLEICKSVSGVEVPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR02</accession>
    <name>X0BR02_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14199</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979333">
        <property type="protein sequence ID" value="EXK81338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR02"/>
    <dbReference type="HOGENOM" id="CLU_007207_0_2_1"/>
    <dbReference type="OrthoDB" id="339764at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08192">
        <property type="entry name" value="MAR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF107">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="2">
        <location>
            <begin position="28"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="3">
        <location>
            <begin position="211"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="415" mass="44664" checksum="E4D21D5B43889232" modified="2014-05-14" version="1">MAFTFGDETCYPAYEGRETPKVSYGLRFPEACLRHCRDTLSTSKVYVICSKSLAQSTDALERLRSALGSSIAGVRIGINPHTPIAQVLEVVNDASSLNIDCLVTLGAGSLTDAAKLVRLALANSATSEEEMNTLWGTPKSNPMLRNNISKPTIPLIHIPTSLSGGEFQAIAGGTESQGHAKRTFHCEGVDPELVIQDPELCLTTPEWVWLSTGIRAVDHCVETLCSLVSNDKADEWSKKGLVKLVSGLLASKADPKSLQARHLCHQGVVSSMCAVSSGVPLGASHAIGHQLGPLGVGHGETSCILLPAVCRFNFDKKANVERQEVVRDLLLEQDEVGQLLQVKGLDKSAVSLADILDVFISTLGMPRSLEEVGVGEDKLEVLARNSLDDIWIQTNAFPITETSQVVEILNMCVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BR75</accession>
    <name>X0BR75_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">adenosylmethionine decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_11625</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic AdoMetDC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.50" evidence="4"/>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BR75"/>
    <dbReference type="eggNOG" id="KOG0788">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023050_0_1_1"/>
    <dbReference type="OrthoDB" id="1068353at2759"/>
    <dbReference type="UniPathway" id="UPA00331">
        <property type="reaction ID" value="UER00451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006597">
        <property type="term" value="P:spermine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.50">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048283">
        <property type="entry name" value="AdoMetDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001985">
        <property type="entry name" value="S-AdoMet_decarboxylase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018166">
        <property type="entry name" value="S-AdoMet_deCO2ase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00535">
        <property type="entry name" value="SAM_DCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11570">
        <property type="entry name" value="S-ADENOSYLMETHIONINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11570:SF0">
        <property type="entry name" value="S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01536">
        <property type="entry name" value="SAM_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01336">
        <property type="entry name" value="ADOMETDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="6" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="12" id="KW-0704">Schiff base</keyword>
    <keyword evidence="8" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK84371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="494" mass="54388" checksum="EB0AA329A0E2FB46" modified="2014-05-14" version="1">MTSVPYNCTFSPASATPHLTINHDVAADLDSTNAFEGPEKLLEVWFAPSPTTLPPTAPVNGLKAVPADTWVPMLDMVNCKVLSVLESEMMDAYLLSESSMFVFPHKIILKTCGTTTLLLGLQRMLHIAAKHGFPFHNANSADDIQAAATPYRVFYSRKNFLFPERQQGPHRSWKQEVKYLDDMFDGGSAYMVGKMNGDHWYLYLTSPNQQALTPPRTPGEVEGTKIPVGTSFNGLPSSYHDETLEILMTDLDPENAKQFYLSHASAVASDKMAAEAKDARKEAINSLGGLAETVDEVDVFANEDDTMLYSIEALTTEGHALGTVVSESCGLSSVYPTSKYPDARVDAYLFSPCGFSANGVVPPEAGKGEHYFTVHVTPEPQCSFASFETNVPGGQSGRTTTEIIEHVVDIFKPGRFSVTLFEAKGAAQNPYCMGDDDSNNWAAKRLVDPVRGYRRIDRIVHDFEDYDLVFRFYEREGWAGTKNARVGEPVSPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BS78</accession>
    <name>X0BS78_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BS78"/>
    <dbReference type="eggNOG" id="ENOG502SXKU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115019_1_2_1"/>
    <dbReference type="OrthoDB" id="4892971at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02118">
        <property type="entry name" value="EthD family reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40260">
        <property type="entry name" value="BLR8190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40260:SF2">
        <property type="entry name" value="BLR8190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="11"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="99" mass="10837" checksum="5CC3EB190912A4C4" modified="2014-05-14" version="1">MATVVIQYPVGHDFDVDYYVNTHMPLAHKLWGPQGLISGQVIKLGGDSPHQIYSIITWDSLASFQKASVSEEAKEIKADVKNFTTATPTYVIGETVAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSM2</accession>
    <name>X0BSM2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14125</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658427">
        <property type="protein sequence ID" value="EXK81489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSM2"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF27">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="379"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="27"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="520" mass="56378" checksum="15A155982674D4B8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSY3</accession>
    <name>X0BSY3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSY3"/>
    <dbReference type="eggNOG" id="ENOG502SKTW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031387_1_0_1"/>
    <dbReference type="OrthoDB" id="5386330at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF17">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="63"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="465" mass="51550" checksum="2726376E9DDD9F4C" modified="2014-05-14" version="1">MSLAKRNNGCYECCKRRLRCDKTEPECLKCQKKGIACSGQGLRCRYSSHMAVDSTPGAGKPLTLTFISSSTPAEPQPGKSLRWVDSAQRARKERARKTKGRAPSDSPTSSNPPDSASSDDATSPSSDDSASEFGGVVVPYRYGVTIHPALNEASNAQTRRLFSHFSEIIAGHMVVLDSFSFSNGYRDVILPLAHQDENLAQAVSVVSAFHLGQRDPKLQRIAEAGHQAIVQKLRRDSLQLSPEQLFNPYILATILVLLVGETITGADNYTYLLEMLNCLTQYPDWISMLPPSLKDFFLQQIKMFQLFGVPLANESKGLKVLTGPEAYLDFMSYPELPPQSEHFTNIETIRSAIFDACSIYRRRAESSLSDDESIHLVEQLRLKVLNLDCSTKGAHALVWTYFIAAAESILPEHREFFAGRLADLYSVTNFGSIPVAVKALGTIWSMQGTRRWTEIVSSETPILIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0BU49</accession>
    <name>X0BU49_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_13670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK82029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BU49"/>
    <dbReference type="HOGENOM" id="CLU_006632_3_0_1"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="28"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK82029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="719" mass="80696" checksum="140733A4EFB873EA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVL4</accession>
    <name>X0BVL4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10341</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVL4"/>
    <dbReference type="eggNOG" id="ENOG502S3FG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007607_0_0_1"/>
    <dbReference type="OrthoDB" id="3364175at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052783">
        <property type="entry name" value="Metabolic/Drug-Res_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655:SF2">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="133"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="640"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="747" mass="81986" checksum="3940B28FBED4790E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVQ1</accession>
    <name>X0BVQ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13021</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVQ1"/>
    <dbReference type="eggNOG" id="KOG1371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_1"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43574">
        <property type="entry name" value="EPIMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01713">
        <property type="entry name" value="NUCEPIMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="16"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK82589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="307" mass="33893" checksum="8262CF31FDDE555A" modified="2014-05-14" version="1">MTIITRIRISKPRRAILVTGGAGFISSHLVEALLAEGGWRVVVVDNFDEFYDPEIKRANLALHLLNPNLKLYEADIEDLEALQTIFTDNGFSAIVHLAARAGVLPSLSQPNKYFDTNVNGTLNLLQCAREFDVKQFLFGSPSSVYGLGAKAPFSENYKSTQPISPYATSKSAGELLCHTCSHLYDIRCICLRFFPVYGPRQHPDLAIHKFTSLIHQGKPIPLFGDGSSRFFNLGESQTIQLRDLIGAPEDTLGRKTRIDRKGEQAGDMPITYADISKAGAMLGYKPKTQVQQGIVKLVAWYLSQCGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX74</accession>
    <name>X0BX74_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_12228</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX74"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_3_1"/>
    <dbReference type="OrthoDB" id="5215911at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF50">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="50"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK83533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="527" mass="57921" checksum="19876AAAF89166BA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXP4</accession>
    <name>X0BXP4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_12456</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH658404">
        <property type="protein sequence ID" value="EXK83274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXP4"/>
    <dbReference type="HOGENOM" id="CLU_000288_81_1_1"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="60"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK83274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="409" mass="46879" checksum="7EDC47D7C7277A76" modified="2014-05-14" version="1">MASFLRKIPWPGRAWKPLVFSNPSFQKVPIEEKIEEELFPDYVASRYYPAKIGEVLRDRYQVVGKLGFGASSTVWLARDLDGRRHVALKLFINSQSMGQQLDNELEMYKRISAASSKHPGRSAVRELLDSFDVAGPDGSHRCLVHPPLWESIWTFLNRNPVGRLPPVVLAVTLRRLFLALDYLHTECEVIHTDIKGDNIMFGIYDDSVFTAFEEEELSDPTPRKEVDGRTIYISRELRKPKDYGAPVLCDFGSAVPGDVEHCEDIQPDIYRAPEVILQAPWSYKVDIWNAGCMIWDIFEGRHMFTGHDPEFQKYRSRAHLAEIIALLGQPPSEVLQAGKASHKFFTDTGDFRNEIDIPERTSLAQQEISLEGERKEMFLAMMNRMLQWDPAQRSSAKELAEDPWIMAYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BY94</accession>
    <name>X0BY94_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BY94"/>
    <dbReference type="HOGENOM" id="CLU_2867702_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="64" mass="7496" checksum="B2548B0C58582A7A" modified="2014-05-14" version="1">MQRYLSCTCDNHIRSWLRNGICEWQLAIGFGPADPGHELEKENMIGNDEKDMLQRNENLSLLYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZB4</accession>
    <name>X0BZB4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="3 8">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_12016</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZB4"/>
    <dbReference type="eggNOG" id="KOG1175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05966">
        <property type="entry name" value="ACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000004">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000001">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001208">
        <property type="entry name" value="PRK00174.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="11">
        <location>
            <begin position="40"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="9">
        <location>
            <begin position="98"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="10">
        <location>
            <begin position="544"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00073617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK83859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="663" mass="72749" checksum="A62A05F4634ACDC3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZD5</accession>
    <name>X0BZD5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZD5"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078327_0_0_1"/>
    <dbReference type="OrthoDB" id="19174at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="218" mass="23865" checksum="45ECB9E6911EA18A" modified="2014-05-14" version="1">MATPNPFLLAADNNPTLLPLLRENPALASSQDEHGYSLVHAAASYNHLDLLRALVREFNVDVDLKDEDNETALFVVETQDAAQVLVEELGANINHRGSEGLTAREKIEAEAEFPAVAEYLAMIEAKKADDPASTAAAVMPEVIPHPPEGMKVSVGTMDETTDIPEEIDPEFRRRIEELAQRDDFNTPQGQAELRKLVEDAVLGEGGVGDERNVRSKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZD8</accession>
    <name>X0BZD8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein disulfide-isomerase</fullName>
            <ecNumber evidence="5">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_11542</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="5"/>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZD8"/>
    <dbReference type="eggNOG" id="KOG0190">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025879_6_0_1"/>
    <dbReference type="OrthoDB" id="427280at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF132">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937281" description="Protein disulfide-isomerase" evidence="11">
        <location>
            <begin position="20"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="12">
        <location>
            <begin position="331"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="485"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="494"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK84283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="511" mass="56811" checksum="877E86EAAC1BA201" modified="2014-05-14" version="1">MFFPTNALILLTYGTFVWTHSVRDLGAQDFFDLMHSDTIALVLFVTPGCGKCDEITTQFEQASDLSPKASFARVDCSTEGKVCDDVKVLHVPEVRLSRGRDQLTLYSGALDTSALLLLIERQHGPAVMELSDANYHEFLSTDYVSVVAFINDQDEDSIKVYTQVAEKLRGEYAFAITRNSSRANDEGITRPAIMLVSTFDERRSSYEGPFEHESLEMFIQKHGTPLIGELHPEVYASFSETNLPLAQILVPSLTERDHLVDSLYPLARRYANVLTFVTVDTSRYPQRAAMLNLADGIKLGFAIEDVISTEKFPLKSKPVNAESITTFVKDFVAGKLKPEVRSQPAPEKQQGLCLELVGHTFRETAFDETRDVLVEFYTPWCDYCLESHAVLEKLAIHYRDAGLGDSISVAKIDVSSNDVPELITGYPTLKLYPAGGHPPVTFDGNYHEPIPLVTLISFIHDNGRNQLKAKPSLFSHSSTMSEASIPLEAGQDDLSSKSSDRANSSLKHEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZR3</accession>
    <name>X0BZR3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_19211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979637">
        <property type="protein sequence ID" value="EXK76027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZR3"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_0_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936840" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="5">
        <location>
            <begin position="23"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="302"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="547"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="590"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="121"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK76027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="609" mass="65113" checksum="8F19699C435980D5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1L2</accession>
    <name>X0C1L2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11176</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1L2"/>
    <dbReference type="eggNOG" id="ENOG502SHBD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008137_0_0_1"/>
    <dbReference type="OrthoDB" id="2571985at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF15">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="183"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK84654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="764" mass="85423" checksum="C59F153BFD236954" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C275</accession>
    <name>X0C275_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conidiation-specific protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C275"/>
    <dbReference type="eggNOG" id="ENOG502STRE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122062_1_1_1"/>
    <dbReference type="OrthoDB" id="2137750at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019626">
        <property type="entry name" value="Stress-induced_KGG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052590">
        <property type="entry name" value="Stress/Virulence-Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36569">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36569:SF5">
        <property type="entry name" value="CONIDIATION-SPECIFIC PROTEIN 10 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10685">
        <property type="entry name" value="KGG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="77" mass="7816" checksum="C30891F255FCFCC8" modified="2014-05-14" version="1">MTGTDNTNPGNFANRPKEEVQEIASKGGKSSHSGGFASMDADKQREIASEGGKASSGSFEPGSEKAKEAGRKGGLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2W8</accession>
    <name>X0C2W8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2W8"/>
    <dbReference type="HOGENOM" id="CLU_776218_0_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF1">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE EPSILON SUBUNIT HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="357" mass="41034" checksum="D3882CED6DBD952F" modified="2014-05-14" version="1">MSTQTLGLLAALDAIHNSQGVQSYGRHEDIKPENILWFKLDNEPHGLLVLEDFGLTKFHRERSRSFTRNTNVGYTYTYAPPEIDIKGGFMSRSSDVWSFGCVLLEMVCWLLGGWELSEAFADARLTEDASGIMKTDSFFAIFKLENDELRRFTVKPQVLDFIRRLDHHESCTNYVHDILDIIEKYMIVVRTEDVKRASTSELLEKFRGVDQRVQDDSQRDYIAKPTHGPRKTPPKALIAVEAHVVNRKYTYSRQSRLRLTQKFTERSQQSQRQSIRVRQIDDADLVIREPHSMTGDETISGKKEFSPEKLLNADKSGLAAAQMIEAKVFEALESFDHTDTCLAKFLVHWQVPVCVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C365</accession>
    <name>X0C365_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_18086</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979406">
        <property type="protein sequence ID" value="EXK77202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C365"/>
    <dbReference type="HOGENOM" id="CLU_1337556_0_0_1"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="7">
        <location>
            <begin position="2"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK77202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="205" mass="22877" checksum="A083900C6D3A0246" modified="2014-05-14" version="1">MFSSLIQQIMPKFIVQRTLYEVRERHSNMYSWSVLILANILVEIPYRYYVVLGVMTFAIFNYTVFGVRSSEDQGLVLLFFVYFYILAGTFAHMVVAPLPDATTAGRVVTILFPMMISFSGVFQNPIALSGFWIFMYTVSSMTYLVGGVAVSGVSGDPIVCSHAELAVFQPPTGETCGHICSHISSKLLWERCSTRMPLLAALIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3N0</accession>
    <name>X0C3N0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3N0"/>
    <dbReference type="HOGENOM" id="CLU_3279504_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="41" mass="4680" checksum="E8D2D4B5E374A2D3" modified="2014-05-14" version="1">MADTIESLKPFNFIVEFITVLKPKYFEGKNPLCGRFLGVIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3Q9</accession>
    <name>X0C3Q9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10523</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502QQDH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000739_1_1_1"/>
    <dbReference type="OrthoDB" id="2546325at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="428"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="2145" mass="239832" checksum="2D93CA8070D8B524" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3R4</accession>
    <name>X0C3R4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trichothecene 3-O-acetyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979390">
        <property type="protein sequence ID" value="EXK77412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3R4"/>
    <dbReference type="eggNOG" id="ENOG502T20N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026450_4_0_1"/>
    <dbReference type="OrthoDB" id="1862401at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF310">
        <property type="entry name" value="FATTY ALCOHOL:CAFFEOYL-COA ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="55132" checksum="2CC0FB25476AE17C" modified="2014-05-14" version="1">MAPAKTEVLVIDQPALHSKTFATEKVTPLPDLAPPLLPTEKIGPMGWIRSLLHFELGESYNAEEVTSILKRAYSAFKDRTPIAGCEAVPTAEYLETGLLQLRHYGDEIEHDFLVKDLRGEDFPSFKELKRRGYPSSVLDPDVVCQRGLGGEWPRAGDRLNTTMVQLNFIKGGLLLNVLFLHAYIDGTTAYKFTEIFAEEVRKAQGLPITNPVEIPCEDRAKLMKPSDTIVGKPEDHPEYIEVPFTPEGPPPKLASPIHHGHIFYFSSEKIQELKEAAAPRNAKLFKSDDTSSYISTTDALTALVWRCTMTAQHGKKEGEDKPTGPSMVGLALDARRRAGKPIHKHTLGNILGFAPAILDIEKVLEHEDVSLADVALVVRGAVNKSKDTYLATISSLVDSIGNVSRLIPAIFLDMPGNHALFSSWREFPFYDIQWGPALGGQIKAIRPPSVGVTHSMHIILPDRPDAGPGVEVFVGTENSAMENLLENPLWRQYAQGPEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C634</accession>
    <name>X0C634_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit GON7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_09948</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GON7 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C634"/>
    <dbReference type="HOGENOM" id="CLU_146833_1_1_1"/>
    <dbReference type="OrthoDB" id="2288868at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014849">
        <property type="entry name" value="EKC/KEOPS_Gon7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08738">
        <property type="entry name" value="Gon7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0779">Telomere</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK86259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="73" mass="8111" checksum="C80F8721967E8038" modified="2014-05-14" version="1">MPRPTLTADYKSPATSTADKSSYLKALRASVADTQDTINKELTARMEQDKARDAAAEAKEEENYGEEVQEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6J9</accession>
    <name>X0C6J9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16957</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658526">
        <property type="protein sequence ID" value="EXK78357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6J9"/>
    <dbReference type="HOGENOM" id="CLU_020223_1_0_1"/>
    <dbReference type="OrthoDB" id="2283488at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="323"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="676" mass="75327" checksum="D170D974D106DC62" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C809</accession>
    <name>X0C809_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C809"/>
    <dbReference type="HOGENOM" id="CLU_2277621_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="102" mass="11398" checksum="B77A46C7435A465C" modified="2014-05-14" version="1">MRQKPEVEESKIERSKESKRSEVSMRSEVSVRCGGSVVSKRPEKRGKPSKPMEGEVPEDSDTEKSESEKSEPDELERVKSVSDIPKSEKSESPGSESEVDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8P7</accession>
    <name>X0C8P7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Endoplasmic reticulum vesicle protein 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_06931</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8P7"/>
    <dbReference type="eggNOG" id="KOG1691">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066963_3_0_1"/>
    <dbReference type="OrthoDB" id="759142at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936832" evidence="9">
        <location>
            <begin position="24"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="10">
        <location>
            <begin position="38"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK90780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="218" mass="24719" checksum="D76B5F81C621A5BD" modified="2014-05-14" version="1">MALQQTLVQYICSVLLLVSAASALKFDLIAQAESSKRERCVRNFVGKDTLVVVTATVDGYKGDGMVVNLYIRDAVGNEYGRPRDVVGESRTVFTSHADAAFDVCFENIVTGSQRINNPTRHVELDIDIGADAKDWSAIQATEKLKPVEAELRRIEEITGELVTEMEYLRAREQKLRDTNESTNNRVKWFGIATTWLLIGLWAWQIMYLRAYFRSKHLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9E0</accession>
    <name>X0C9E0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9E0"/>
    <dbReference type="HOGENOM" id="CLU_2941771_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="62" mass="6645" checksum="2BFF9703ABA4C3F7" modified="2014-05-14" version="1">MRFYGQRAHLTPSAATAPYPPPSASSIAEVPCLASLEGNHSNRFGGKWPTLLQYRAKGGNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9L0</accession>
    <name>X0C9L0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ferulic acid decarboxylase 1</fullName>
            <ecNumber evidence="1">4.1.1.102</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phenacrylate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FDC1</name>
        <name evidence="5" type="ORF">FOQG_16023</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(E)-4-coumarate + H(+) = 4-vinylphenol + CO2</text>
            <dbReference type="Rhea" id="RHEA:33227"/>
            <dbReference type="ChEBI" id="CHEBI:1883"/>
            <dbReference type="ChEBI" id="CHEBI:12876"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="EC" id="4.1.1.102"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(E)-cinnamate + H(+) = styrene + CO2</text>
            <dbReference type="Rhea" id="RHEA:46920"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15669"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:27452"/>
            <dbReference type="EC" id="4.1.1.102"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(E)-ferulate + H(+) = 2-methoxy-4-vinylphenol + CO2</text>
            <dbReference type="Rhea" id="RHEA:33807"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29749"/>
            <dbReference type="ChEBI" id="CHEBI:42438"/>
            <dbReference type="EC" id="4.1.1.102"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>prenylated FMN</name>
            <dbReference type="ChEBI" id="CHEBI:87746"/>
        </cofactor>
        <text evidence="1">Binds 1 prenylated FMN per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. May form higher order oligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiD family. UbiD-like/FDC subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.102" evidence="1"/>
    <dbReference type="EMBL" id="JH658473">
        <property type="protein sequence ID" value="EXK79372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9L0"/>
    <dbReference type="eggNOG" id="ENOG502QR5I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023348_0_0_1"/>
    <dbReference type="OrthoDB" id="4878259at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046281">
        <property type="term" value="P:cinnamic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033494">
        <property type="term" value="P:ferulate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1670.10">
        <property type="entry name" value="UbiD C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01983">
        <property type="entry name" value="UbiD_FDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032903">
        <property type="entry name" value="FDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049381">
        <property type="entry name" value="UbiD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049383">
        <property type="entry name" value="UbiD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048304">
        <property type="entry name" value="UbiD_Rift_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00148">
        <property type="entry name" value="UbiD family decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="3-OCTAPRENYL-4-HYDROXYBENZOATE CARBOXY-LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108:SF17">
        <property type="entry name" value="FERULIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01977">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20696">
        <property type="entry name" value="UbiD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20695">
        <property type="entry name" value="UbiD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143968">
        <property type="entry name" value="UbiD C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-octaprenyl-4-hydroxybenzoate carboxy-lyase-like N-terminal" evidence="3">
        <location>
            <begin position="43"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="3-octaprenyl-4-hydroxybenzoate carboxy-lyase-like Rift-related" evidence="2">
        <location>
            <begin position="145"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="3-octaprenyl-4-hydroxybenzoate carboxy-lyase-like C-terminal" evidence="4">
        <location>
            <begin position="354"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="196"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>prenyl-FMN</name>
            <dbReference type="ChEBI" id="CHEBI:87746"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="218"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>prenyl-FMN</name>
            <dbReference type="ChEBI" id="CHEBI:87746"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>prenyl-FMN</name>
            <dbReference type="ChEBI" id="CHEBI:87746"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>prenyl-FMN</name>
            <dbReference type="ChEBI" id="CHEBI:87746"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK79372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="528" mass="58207" checksum="B16915FCCDDF8CEF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAI5</accession>
    <name>X0CAI5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxidase</fullName>
            <ecNumber evidence="14">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_15770</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Forms a one-to-one complex with cytochrome c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="14"/>
    <dbReference type="EMBL" id="JH658465">
        <property type="protein sequence ID" value="EXK79672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAI5"/>
    <dbReference type="HOGENOM" id="CLU_036959_1_1_1"/>
    <dbReference type="OrthoDB" id="2859658at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00691">
        <property type="entry name" value="ascorbate_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000009">
        <property type="entry name" value="Ascorbate peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000005">
        <property type="entry name" value="Cytochrome c peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 14 16" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="15">
        <location>
            <begin position="103"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK79672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="358" mass="40050" checksum="2628048005367B4D" modified="2014-05-14" version="1">MGSVIQQLSRRATRVTARKAFTISPHHAFCQGRRYYSSEPNQKSSSAWVWLTGAGTAVGVGFYFKSRGATPSISHVFIPTKEDYQKVYNEVAALLEEKDDYDDGSYGPVLLRLAWHASGTYDKDTGTGGSNGATMRFAPESGYGANAGLVAARDFLEPVKAKFPWISYSDLWILAGVCAIQEMQGPIIPYRPGRSDREAAACAPDGRLPNATKGAAHLREIFGRMGFNDQEIVALSGAHALGRCHTDRTGFTGPWTFSPTVLTNDFYRLLIGEEWQWKKWDGPAQYEDKATKTLMMLPTDMVLIQDKKFRPYVEMYAKDNNAFFRDFSAVILRLFELGVPFARGTENQRWTFKPTWDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAR5</accession>
    <name>X0CAR5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658461">
        <property type="protein sequence ID" value="EXK79762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAR5"/>
    <dbReference type="HOGENOM" id="CLU_012494_5_0_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF6">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="2">
        <location>
            <begin position="85"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="242" mass="26449" checksum="9ECED1EF32AAF97F" modified="2014-05-14" version="1">MSDQIDSANIRMKLNPKQLTAFLAANSTGVGVLVCPGGGYSVMSISYEGFGPAEYLNTLGIDAWVLNYTTASIKTPPLYPTPMDEALAAVELIRKQSPGTKKLGVMGFSAGGHLAGTTLTTPKAKLDFGILSYPVITMEDDYTHENSRYNLLGNNPTRKQIESLSVQNRVSDKTPPTFLFHTSNDELVPVQNTYLYANAMAKHGRKVQVVVLPDGKHGIGLGVDDPVRDWRPELERFLKYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBU9</accession>
    <name>X0CBU9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15284</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658450">
        <property type="protein sequence ID" value="EXK80152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBU9"/>
    <dbReference type="HOGENOM" id="CLU_079681_1_0_1"/>
    <dbReference type="OrthoDB" id="3535998at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="28528" checksum="F364C4F2993D56F9" modified="2014-05-14" version="1">MIQSLSTEPAKPKRNNTRRVSTLTPEQLARKRANDREAQRAIRIRTKEYIERLERELAELKSNQSRDQTIQDLLRRNTAIERELIRLKEITGAPAASLSCHESDPTARQLLFPDELSTTAPQPTTTTTTTTTVCNGNVSTGSAAISSTHRAPFSGDYNSHHDYNQQYIPLSNNCESLASTISCAVPSNISTSSTPGDYSVRNIQTSMTTSVLPFSNTSSSNICTIYDKDVIKVEYIEVGYLGAIPQPLHQTDMRYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CC65</accession>
    <name>X0CC65_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CC65"/>
    <dbReference type="eggNOG" id="ENOG502SDQB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030809_1_0_1"/>
    <dbReference type="OrthoDB" id="61870at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053225">
        <property type="entry name" value="Acyl-CoA_N-acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958:SF6">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="35196" checksum="C967BAF17E1CAEE7" modified="2014-05-14" version="1">MVDFVKVYTTVPKQLLALLTNQLPYSLPLLRRLQFTKFENGLRETARVILAAESQLEDGLDFPKRFTAAYIDVGGGPDTQTWIYSTLEHPNDADPKDTAVYEKQLHKIIEESVVIAKAHGRPLVYGEAVLVGTLHDSVRDLLYKTGRVQARETGAYDKWLFKYEDLPKDETALPEGMHWGTATDDDCRVVISRTNIPRTVQVLRRMPSLVIKLDDGTPVSWAFLGFDGSLISLHCEEPYRRRGLAKTLAAKLFREKSLDFADDGWCSADVAPDNDGSRGMCKRLNGKPTWRVSWVLLFVGEKPPNETNGTKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDJ9</accession>
    <name>X0CDJ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658438">
        <property type="protein sequence ID" value="EXK80692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDJ9"/>
    <dbReference type="eggNOG" id="ENOG502T5TQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152679_0_0_1"/>
    <dbReference type="OrthoDB" id="4860686at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937565" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15574" checksum="1E5F44CD0C3910D8" modified="2014-05-14" version="1">MRFEIAAVIMALAMNVSADRMEIFTKCTLGCDSSDAFFYTDYGAYKVNANEGCRSTSVPGMVEFCVDWGKRRSHFRFSGQNKRCLIQDSESAYGCAYNSCWKTTWKEISCHWREAPNPDIEKEPVSSAAAAKATASAFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEX4</accession>
    <name>X0CEX4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phenylacetaldoxime dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEX4"/>
    <dbReference type="HOGENOM" id="CLU_065607_0_0_1"/>
    <dbReference type="OrthoDB" id="3359285at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025702">
        <property type="entry name" value="OXD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13816">
        <property type="entry name" value="Dehydratase_hem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK92970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="40065" checksum="C15B5EA555D09758" modified="2014-05-14" version="1">MSCPARIYPLRKPEGHKLPIPRWHLALPDDVTHVCTTYIGVQSHSDTQDADIARNKATEIIQAWVSSDTGPEAYETFAVIDGCDVQESTIWVCYWSDKTKYEKGLNDLSLNSIYAQLPETGRASVGIWREAFITEFPRLETNYSGLDYLPGLAKLPGASFPEHTLSAYWGAARDRIPSSAYDLFPPSNPTPPVTFPPGVGQYLIGTNAENLAHIRSGQFWENCGQQEADSYDKKLEPTLHSGLQYLWDNSPDTGALGLRYLRNQDPSVEETRSRKESCGAGFFANLEALETWAKSHKSHLAIYRGALAHYKTFGDARKFRTWHEVSVMRAGDARFEYLNCVPETGVIRGVTLKAENLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGM3</accession>
    <name>X0CGM3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05458</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGM3"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_23_1"/>
    <dbReference type="OrthoDB" id="5057215at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031353">
        <property type="entry name" value="NACHT_sigma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17106">
        <property type="entry name" value="NACHT_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="5">
        <location>
            <begin position="148"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="687"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="787"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="820"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="854"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1055"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1190"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1224"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1258"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK93331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1280" mass="143553" checksum="EFAB44D916BB3D0A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CH76</accession>
    <name>X0CH76_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Telomere-associated protein Rif1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_04961</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502QSZW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000830_2_0_1"/>
    <dbReference type="OrthoDB" id="5399929at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140445">
        <property type="term" value="C:chromosome, telomeric repeat region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022031">
        <property type="entry name" value="Rif1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22928">
        <property type="entry name" value="TELOMERE-ASSOCIATED PROTEIN RIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22928:SF3">
        <property type="entry name" value="TELOMERE-ASSOCIATED PROTEIN RIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12231">
        <property type="entry name" value="Rif1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Telomere-associated protein Rif1 N-terminal" evidence="8">
        <location>
            <begin position="145"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1119"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1480"/>
            <end position="1730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1188"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1227"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1306"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1329"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1446"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1491"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1522"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1581"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1618"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1654"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1689"/>
            <end position="1720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK93750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1773" mass="197442" checksum="5860CA64D4F64CD3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHC5</accession>
    <name>X0CHC5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier protein] reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05013</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHC5"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="OrthoDB" id="4131217at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF66">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK93815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="302" mass="31851" checksum="54B6AFB5F1FC64ED" modified="2014-05-14" version="1">MSDKAQSRINAIGKQLLPPINKVAPGSSKLRVEGKVVIITGTNSPLGIGRATAHQYAESGARALYLCDFDDTHLESHKKEINAAFPKVEIHTRRFDAADEDKVKEVVDDAIQRYGRLDVFFANAGVVGRTTLFSDFSKDEFMSILNTNTSSVFLAAKYAAPAMMQTSADKPQASGSIIGTASVAGIRSNAGSTPYSASKAAVVSLAQTISYQLAGTGVRMNAICPGLIETGMTAPVYEAARARGSEKKIGQLNPMKRGGHADEIARVALFLGSDESSYVNGQAWAVDGGLSAGHPFVPGKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJU0</accession>
    <name>X0CJU0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJU0"/>
    <dbReference type="eggNOG" id="ENOG502SMYH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053552_0_0_1"/>
    <dbReference type="OrthoDB" id="5226911at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="274" mass="30977" checksum="999D0FC27B967FD7" modified="2014-05-14" version="1">MGNFGTAVNSLLGTYTKCLSLLKGFPKDEDAGTLSETRSTLSTSLRSDRARVRREYASRLSQDGSRFEKGDAPARSALRRIVRKLTNTLADVVRSFQDPKGQPINCESLLALSTGSSLDAVRAMNDLSSRVGSTSSSSSRGSIVSRGRQRSRRHSQKTGIKSKRRSTEERSKREKTRSKKPTSQSRSRRRTSSDRLHRQHGSRSRQPPEIKGPHNRVSIVTIASDSTKLGEIRRRLSKQMPLEEYENRVAYPLYAYHAQEAPVRKKWWNPFRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJV0</accession>
    <name>X0CJV0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJV0"/>
    <dbReference type="eggNOG" id="ENOG502S5IN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047851_1_0_1"/>
    <dbReference type="OrthoDB" id="5427526at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="376" mass="41119" checksum="1FC7168C2C315FD0" modified="2014-05-14" version="1">MPSSPHTPRHSRNSSAFDSFSGSPQARRLSKSSVQEPSTPFRNSFNQQDASDLGGNGMGNLADELADAFSDSGDEGEYTDGDANSDMFGAEGQGQGNDQIDEIEDTEDTNSPKKQGSDRAKAMNLTLLSPRRKHQRQTSNYDGSEYGSESDLDSPGMPPGLVSKMDAVESLARRGTENYGGPADDVFKRVTNALRDLGSQSSVEASASRLITAHSALTTHLNHQSRQIHNLSFSLLSPLVAPPDPETIDDLIPLLLNLSDAMPRPSTSAFNSLTSLHTLTTELVQNLNYLSDTLHMSRQTTTMATRRLKSAKEIVAEMRREEELREEGERWLTRGNWGERLEKRECAGVCGDVIGGFEEVCNGWRERLLAQAEAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CL33</accession>
    <name>X0CL33_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fcf2 pre-rRNA processing C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_05999</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CL33"/>
    <dbReference type="eggNOG" id="KOG3100">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075129_1_0_1"/>
    <dbReference type="OrthoDB" id="427886at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="4">
        <location>
            <begin position="80"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="21"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK92023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="198" mass="22193" checksum="D41E7B6BC9CCBE05" modified="2014-05-14" version="1">MTDISDDQVDELLRKAEQRLKDGSASAIVSSTTSNAVVAGDAATTKDVKQQNSSNSSSKKDGLTVRAPPQPQLGLKAKEKSTAGPEWFDLPKTNMTPEFKREWQVLRMRGILDPKHQKKNLRASAPEYSQVGEIIAGPTEFFSARLTRKERKNTLLEEVTRDLDSHKFTDKYAGIQKQKTSGKKAFYKNVVAQRRKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLP8</accession>
    <name>X0CLP8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_12178</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLP8"/>
    <dbReference type="eggNOG" id="ENOG502QTZH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025894_2_0_1"/>
    <dbReference type="OrthoDB" id="10027823at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23520">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23520:SF5">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="355"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="1"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK83477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="460" mass="50108" checksum="8F6B0E986FEE00F6" modified="2014-05-14" version="1">MAVAGRFLSSIGADVLWRSSRDLKILILLRFIRLLGYGGTTLVLALYLNALGFHDTQIGLFMTLTLVGDLAISFILTWVGDRVGVRLTAVVGALLMSAGGVAFAYFENFWLLLLASIVAVINPSANEIDPFKAIEESAIARLSTAHTCNDMFAWWSMLGMFGTAASNLLTGWLINALEDNGMKKVDCHRMIFLSYAGIGLLKLLCSLFLSSEVEQMPLQKESCSTPQSGILTPEEEASDDETAPLLDDNSSGYGAVTQTQAQVLGTAQEKRLFTPASFTFMWKLSLALILDFVGSGLAQISWMTYFFKREYDMPEGALGSATFTAGIISSVLNLASSPLSRAIGQVQTMVLCHTVNSISLLMVSVPGNKYIALVIFIFRIVTREIDNAPRQAFISAGVLDHERTSAMGVVNITKTIGSCLGLYITGLFAGLDKFWLAFILAGALKLSYNVLILAFFWKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRG3</accession>
    <name>X0CRG3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_05069</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the methylcitrate cycle that catalyzes the synthesis of (2S,3S)-2-methylcitrate from propionyl-CoA and oxaloacetate. Plays an important role in detoxification of propionyl-CoA, an inhibitor of both primary and secondary metabolism. Also has citrate synthase activity using as substrates acetyl-CoA and oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>propanoyl-CoA + oxaloacetate + H2O = (2S,3S)-2-methylcitrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23780"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:58853"/>
            <dbReference type="EC" id="2.3.3.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRG3"/>
    <dbReference type="eggNOG" id="KOG2617">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022049_2_1_1"/>
    <dbReference type="OrthoDB" id="8017587at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050440">
        <property type="term" value="F:2-methylcitrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006101">
        <property type="term" value="P:citrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06105">
        <property type="entry name" value="ScCit1-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="active site" evidence="8">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR610109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK93903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="470" mass="51894" checksum="DB419619146B8E28" modified="2014-05-14" version="1">MASVARLSNAALRASLRSTPINGSVFNAVRCYSAKTQTLKERFAELLPEKIEQVKALRKEHGSKVVDKVTLDQVYGGARGIKALVWEGSVLDSEEGIRFRGKTIPECQELLPKAPGGKEPLPEGLFWLLLTGEVPTEQQVRDLSAEWAARSDLPKFVEELIDHCPTDLHPMAQFSLAVTALEHTSSFAKAYAKGINKKEYWGYTFEDSMDLIAKLPNIASRIYQNVFKGGKVAPIQKDKDYSFNFANQLGFADNADFVELMRLYLTIHTDHEGGNVSAHTTHLVGSALSSPFLSLAAGLNGLAGPLHGLANQEVLNWLTEFKKSVGDDLSDKAITDYLWSTLNAGRVVPGYGHAVLRKTDPRYMAQRAFAQEKMPNDPMFKLVSQVYKIAPGVLTEHGKTKNPYPNVDAHSGVLLQYYGLTEANYYTVLFGVSRAIGVLPQLIIDRALGAPIERPKSFSTDKWAELVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRU2</accession>
    <name>X0CRU2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRU2"/>
    <dbReference type="HOGENOM" id="CLU_3207655_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="45" mass="4824" checksum="F22CC1C51A5B66EC" modified="2014-05-14" version="1">MEINIPNNRACQTWHNGTPLSFLLLNKAQASNVAADLGSSRLGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS58</accession>
    <name>X0CS58_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TPX2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS58"/>
    <dbReference type="eggNOG" id="ENOG502SPY3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3946796at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="683" mass="75610" checksum="3F6F515CF15E19AC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT04</accession>
    <name>X0CT04_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT04"/>
    <dbReference type="HOGENOM" id="CLU_2413334_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="92" mass="10765" checksum="E0EE2B1F02EF7FB2" modified="2014-05-14" version="1">MFSSTTSAQHTRTNSPTQKLCRTQTLCAWRRRVFKMLSALRVIGRITYVMRRRRISLAWATSQELVFTRFKIVLTFRRKKLVASAMLTVLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTM4</accession>
    <name>X0CTM4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Guanine nucleotide-binding protein subunit alpha, other</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_04363</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTM4"/>
    <dbReference type="SMR" id="X0CTM4"/>
    <dbReference type="HOGENOM" id="CLU_014184_6_0_1"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010255">
        <property type="term" value="P:glucose mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000007">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000181">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF369">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="45"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="153"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="178"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="203"/>
            <end position="207"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="272"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK94199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="355" mass="40754" checksum="D689C9ADA36592F9" modified="2014-05-14" version="1">MGACMSSSNEEADQKKKSQAIDKILEEDSKRLRKECKILLLGSGESGKSTIVKQMKIIHLKGYSEDELFNYRPTVFKNLVECAKAVIMAMQQFDIEPQNEENKAHAEFLLEYQAESGPQAQIDPKVGAAVQALWNDPAKDLLMEHQTEFYLMDSAEYFFQEAMRIVSSDYLPNEMDVLRARTKTTGIYETRFQMGQLSIHMFDVGGQRSERKKWIHCFENVTSIIFCVALSEYDQVLLEESSQNRMMESLLLFDSVVNSRWFMRTSIILFLNKVDIFKQKLSRSPLGNYFPDYSGGNDVNKAAKYLLWRFNQVNRAHLNLYPHLTQATDTSNIRLVFAAVKETILNNALKDSGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUI5</accession>
    <name>X0CUI5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUI5"/>
    <dbReference type="HOGENOM" id="CLU_3050343_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="54" mass="6347" checksum="D0396898EE8F3890" modified="2014-05-14" version="1">MRHDWWQSNAGRAQQKREGRRLSVKVVSKHLLVEIALALANLRRRAKRVNDWAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV88</accession>
    <name>X0CV88_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV88"/>
    <dbReference type="HOGENOM" id="CLU_2145953_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="112" mass="12750" checksum="D791CC1C7794D236" modified="2014-05-14" version="1">MLILQQTWCARLRRTWNAWPGMYIEPRHSAAEPNSPILKHKTSKDQNVRSTATIRWCIAIDAFACASFDPSEELGQSVDEALVQPDERSCQSLPIMTLFCGRDYEEAGLLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWN4</accession>
    <name>X0CWN4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03007</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWN4"/>
    <dbReference type="eggNOG" id="ENOG502QPQM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030747_0_1_1"/>
    <dbReference type="OrthoDB" id="5784at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070916">
        <property type="term" value="C:inositol phosphoceramide synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006676">
        <property type="term" value="P:mannosyl diphosphorylinositol ceramide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03386">
        <property type="entry name" value="PAP2_Aur1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.144.10:FF:000015">
        <property type="entry name" value="Aureobasidin resistance protein Aur1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052185">
        <property type="entry name" value="IPC_Synthase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310:SF11">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE CATALYTIC SUBUNIT AUR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="6">
        <location>
            <begin position="209"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="454" mass="50955" checksum="52F101D607D4EDDE" modified="2014-05-14" version="1">MNDFSATLSGKPKLQLLWPEHVNLPFLNTVPHRYRIGRRRTKSKSRPGNEEITSLKTSFNAWDGVRDLQKHHWRTSDLQYAVVGLLILFSFWIAPPAPGVKLLAIIGSVWVLLMPATRQFFLPSVTIWTWLLYFFCSRFIPNEYRPHIWVRVLPALENVLYGANLSSILSAHQHSVLDILAWIPYGLCHFGAPVVCALLMFVFAAPGTAPVWARTFGWMSILGVTIQLLFPCAPPWYEMEHGLEPAAYGMPGSPAGLARIDAIFGIDLYTTNFSTAPVPFGAFPSLHAANAVLEALFMSHCFPQFRTYFIMYAGWVCWATMYLSHHYAIDLVVGGLIASCFFYAAKARWLPRRQEGKITRWEYEYVEYGDRNAISDEEYGEYFGMGLLGRPRADSSDGWTVASSSCSSSSGTLSPTLSEEALPGMLMDMDNNGQLWDGNAPARDVELSEVVVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY86</accession>
    <name>X0CY86_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Regulatory associated protein-mTOR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_01762</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat RAPTOR family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1517">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10262360at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030307">
        <property type="term" value="P:positive regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000514">
        <property type="entry name" value="TORC1 growth control complex subunit Kog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000278">
        <property type="entry name" value="WD repeat-containing protein mip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029347">
        <property type="entry name" value="Raptor_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14538">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01547">
        <property type="entry name" value="YEAST176DUF"/>
    </dbReference>
    <dbReference type="SMART" id="SM01302">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Raptor N-terminal CASPase-like" evidence="6">
        <location>
            <begin position="157"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1281"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="894"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="894"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="904"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="947"/>
            <end position="962"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK99126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1396" mass="158893" checksum="289D66441AB0370F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ11</accession>
    <name>X0CZ11_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ11"/>
    <dbReference type="HOGENOM" id="CLU_3175411_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="47" mass="5602" checksum="EE4743AF5DC60629" modified="2014-05-14" version="1">MYEMYFIMDGLCFLYSGVRVGMKNEERESRGRRRVLVKAVNKSQQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZK6</accession>
    <name>X0CZK6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 17">Pyruvate kinase</fullName>
            <ecNumber evidence="6 17">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">FOQG_00066</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="6 17"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZK6"/>
    <dbReference type="eggNOG" id="KOG2323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00288">
        <property type="entry name" value="Pyruvate_Kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1380.20:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14 17" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="11 17 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15 20" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="18">
        <location>
            <begin position="45"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="19">
        <location>
            <begin position="406"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EXK99596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="541" mass="59452" checksum="B6688E0851C1A55D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0P1</accession>
    <name>X0D0P1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0P1"/>
    <dbReference type="HOGENOM" id="CLU_104706_0_0_1"/>
    <dbReference type="OrthoDB" id="5101182at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="274" mass="31050" checksum="5CFC3BDA8DDFA680" modified="2014-05-14" version="1">MPDTPPSRDLFTAVHMAADTELVASRAAGQSTVSEAGFTLLEKISFNDLLQEWCNTRPATARHNQVISSALRKSFFERFFQLWDSNDTFVSLPQLPPKKLRQTSYEAGLFKANLPVTPSKRKREITKQDYDHRMAGKPAFLSVEFSSEAEGGEFCLVWKDGGSTKVPVEYVKYKEGMAKAMAIEGAITNWDRNERARAENFNTKLIIALARMRIVRFAKAGTQDFPYIPQELRVNNRTIQCKLISDEFEEFFNVMKAVHEGLSRSKVGAPNHMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0U6</accession>
    <name>X0D0U6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">V-type proton ATPase catalytic subunit A</fullName>
            <ecNumber evidence="2">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">FOQG_00598</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Vacuole membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0U6"/>
    <dbReference type="eggNOG" id="KOG1352">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008162_3_0_1"/>
    <dbReference type="OrthoDB" id="1676488at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18111">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18119">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01134">
        <property type="entry name" value="V_A-ATPase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000002">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000008">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000052">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000003">
        <property type="entry name" value="Vacuolar ATP synthase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00309">
        <property type="entry name" value="ATP_synth_A_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031686">
        <property type="entry name" value="ATP-synth_a_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005725">
        <property type="entry name" value="ATPase_V1-cplx_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022878">
        <property type="entry name" value="V-ATPase_asu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003220">
        <property type="entry name" value="PRK04192.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01042">
        <property type="entry name" value="V-ATPase_V1_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607:SF1">
        <property type="entry name" value="H(+)-TRANSPORTING TWO-SECTOR ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607">
        <property type="entry name" value="V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16886">
        <property type="entry name" value="ATP-synt_ab_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="17">
        <location>
            <begin position="199"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="ATPsynthase alpha/beta subunit barrel-sandwich" evidence="18">
        <location>
            <begin position="302"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="16">
        <location>
            <begin position="407"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="19">
        <location>
            <begin position="639"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="19"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="105"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF16886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EXL00411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="788" mass="85953" checksum="1CCCB0259C101841" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0D904</accession>
    <name>X0D904_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D904"/>
    <dbReference type="eggNOG" id="ENOG502RJIT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_527883_0_0_1"/>
    <dbReference type="OrthoDB" id="4776573at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="555" mass="61755" checksum="9E4B8D968D12A903" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9P6</accession>
    <name>X0D9P6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Yippee domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_06717</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the yippee family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9P6"/>
    <dbReference type="eggNOG" id="KOG3399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043857_0_0_1"/>
    <dbReference type="OrthoDB" id="6407410at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034751">
        <property type="entry name" value="Yippee"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039058">
        <property type="entry name" value="Yippee_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13848">
        <property type="entry name" value="PROTEIN YIPPEE-LIKE CG15309-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51792">
        <property type="entry name" value="YIPPEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Yippee" evidence="5">
        <location>
            <begin position="72"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK91302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="243" mass="26609" checksum="8C271EEB65ED6CA1" modified="2014-05-14" version="1">MVRESGISATKPVFPTFLLPSIRLPFSRRHSVSSSSAESAASSAVTTPASSPPNEGILAKAPRGRLSRTSPNTLRCSTCSVDVAFASQVISKGFTGRYGRAFLVAPPAPPAAQTLSNIRVGKSENRQLVTGWHVVADINCGSCSTKLGWKYVDAKEQGQKYKVGKFILEMERVVTYRSWEDAIDEDVAETATPGKDGEEEDIEFDSDDDDECEDIFAGTWDPEVVEERRRRIVSRRSQAESDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9P7</accession>
    <name>X0D9P7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_00259</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9P7"/>
    <dbReference type="eggNOG" id="KOG2655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017718_8_0_1"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000238">
        <property type="entry name" value="Cell division control 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="28"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="318"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK99874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="385" mass="44645" checksum="C4255C365353C125" modified="2014-05-14" version="1">MASATAENASPIGIANLPNQRHKIVAKRGAGFTIMVAGESGLGKTTFINTLFSTTIKNYADHKRRHQKQVDKTVEIEITKAELEEKFFKVRLTVIDTPGFGDYVNNRDSWMPIIEFLDDQHESYMLQEQQPRRQDKIDLRVHACLYFIRPTGHTLKPLDIEVMKRLCSRVNLIPVIAKADTLSPADLAKFKQRIVSVIEAQNIKIYQPPIEEDDEAAAQHARSLMNAMPFAVIGSEKDVKTGDGRIVKGRQYSWGVAEVENEDHCDFKKLRSILIRTHMLDLIHTTEELHYEAYRAQQMETRKFGEARPRKLDNPKFKEEEEALRKRFTEQVKIEEQRFRQWEQKLISERDRLNKDLEQTHAQIKQLEQELEQMQGSAVRSHGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0DA90</accession>
    <name>X0DA90_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DA90"/>
    <dbReference type="eggNOG" id="ENOG502RJQJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054789_0_0_1"/>
    <dbReference type="OrthoDB" id="3921745at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="347" mass="40221" checksum="44AAD14C53098837" modified="2014-05-14" version="1">MSIHPFLKMEGASRRHSAEDPNQTHTYQCSTQPQTPPCSTSGSPRVKIEEFTSLPRLHDAVSPQGNNFVKLPSLGEFDEGVDALIRTHGPVKTWTPLSPLPGLSRNPTALEPLRSITQPQPSWSFQSDDLPNDYPISRRGTISGHNQYLLAVDHPQQPLQGNYRNPDTYYGYGAGSPSLQVPSNTHCYPSPPPDGEGRHINQKYTTEEGDYIIYAWHDKKMKWQRIKQEFAARFGTTPERTIQGLQAWYYRMNQRIPVWDQEGWLCFDNEDDLEPQHVSIKVRERDSQDKPMEPLGIAQRYPERAIHYSWVDAETKFKAQDWAAKRALQYRDRRERRRRKEQRRLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0DG25</accession>
    <name>X0DG25_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DG25"/>
    <dbReference type="HOGENOM" id="CLU_1796574_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="144" mass="16469" checksum="7EF82CD3EF7ED503" modified="2014-05-14" version="1">MLTPILIPHIEVNSGPARARLIRNGEWARCQRKVSQAEEKGRRSGLNIESNAVSMSWRLHVALFRGQAAAFNLLELAKQATFLCQDPGQPHCRSLARPLSRMRKWKASSRMKKRRMELLKDDDMEALAGHNVKLEVEDPDDERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0DIJ0</accession>
    <name>X0DIJ0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DIJ0"/>
    <dbReference type="HOGENOM" id="CLU_129970_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="203" mass="22232" checksum="87AD430260FAFA6E" modified="2014-05-14" version="1">MIFHSSLPFLIYGSWVGIAKVCFNKGCPLGPGIRGGISSFSDSYSRSPRTALFYQSVSMVSPCFVGSQRSSYQTEPMGAALCAIQASRCVPRELPRSIYRFEVIQLILCRSSSSFLVALVKSQPLAQHTSRLRQWAFPPCSILCVLCLVARHIVKLNNPILDFGIGILPLPSHSSAILVNHNISIGEAGPGYGARKQMRNRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0DPW5</accession>
    <name>X0DPW5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nineteen complex-related protein 2-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03420</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DPW5"/>
    <dbReference type="eggNOG" id="ENOG502S5MV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031138_0_0_1"/>
    <dbReference type="OrthoDB" id="429427at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071008">
        <property type="term" value="C:U2-type post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012890">
        <property type="entry name" value="GCFC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028211">
        <property type="entry name" value="Ntr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12214">
        <property type="entry name" value="GC-RICH SEQUENCE DNA-BINDING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12214:SF0">
        <property type="entry name" value="LD29489P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15458">
        <property type="entry name" value="NTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="285"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="366"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK96352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="461" mass="50249" checksum="DD85B038C2462862" modified="2014-05-14" version="1">MSFSAKRKAKVIKIADEDSSENVPSVAGGDSAGSDESVKPVFGAKAGRKPFRQSGLRKSFNPADSEGLGDAPAANDDEDDGPVVVRPAISRSGSLKGKKKSNKSSRLSFGGDDSAAGDDETAELFTPKKLPLGRALENSAIKRGLGTKGLPMRTIGDDDDRPKYSKEYLEELQSSTPNTPQRPSTLPPDDADLMDLDASELEGAVVVDSSEFSQTQPTAILTEAEILEKKERRKRLALEKDFLSVEDDEDPFGRKKKDDTRLIAEDEDLGEGFDNYVEDGGLSLGRRAEKERRKQDRKMMEELITAAEGHTSDSSSDSDAERRIAYEAAQTRAGMDGLKKPRKDPSQDLLQAPPKISPLPSLTECLARLQTTLKGMEEEMKGKQNRVEKLKKEREDIVKREGEVQALLDETGKKYQEAMGQGKVVEGKGVEIPANAPVEMVGARGLETLGTPSRKPEEEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0DRB3</accession>
    <name>X0DRB3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ecp2 effector protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DRB3"/>
    <dbReference type="eggNOG" id="ENOG502RPY8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152686_0_0_1"/>
    <dbReference type="OrthoDB" id="4965518at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738266" description="Ecp2 effector protein domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15729" checksum="2EA567F9A2C0738C" modified="2014-05-14" version="1">MRLLLAFVSLLSLTTAGPVSRSPPDKDGEYLWGCGKTAPFSISDCNELLGWFKTVSKTGWFGIGKVNGLAKYWGSCQLYIQPGPLGHFALEIQQDEFVDVVHRGMVYKCPDKWARTTVKPDNNTWIAFVTEKGWEPHDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0DRM5</accession>
    <name>X0DRM5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DRM5"/>
    <dbReference type="SMR" id="X0DRM5"/>
    <dbReference type="eggNOG" id="ENOG502QQ27">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38045at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000220">
        <property type="entry name" value="UDP-galactopyranose mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734:SF4">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="519" mass="58282" checksum="584502B1391DD9CE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0E0E0</accession>
    <name>X0E0E0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E0E0"/>
    <dbReference type="eggNOG" id="ENOG502S0NF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033551_1_0_1"/>
    <dbReference type="OrthoDB" id="5552418at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="367" mass="39922" checksum="DC50B8EB472F78D4" modified="2014-05-14" version="1">MDDSNRMRRQNEPPVHSNPNQRYSLNDPSQQRRSVAGISNDRYRPASLAGPSSSGRGMGAPGNYSSYYSESSASFSTANMPGTAIAYGSEYGHDSRQAQGFGGYSTAATMMYNVGQPSTQNTVYDAQQFSSRQPAAMQMMPPDVASSYFGSETGASAGPSLQQPAQGSSGSANVYQQSNAMNYASNSMSTVSAMPQATNTADVSMTDDHDYAEGALEEKWVSYQRQLGSIFQEIVNGSLESASETLLSVTSWLLSQVADLGLNLDDTNLHADRIQLWNDFNHAWLGLGQRQIDLMTSSQQLSRTQSLVPKAMIKKMGNELIRLCDGIERHGLVDYQYGVWEDQITAVLEDCLDLYDASEEGSDSGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0B0E2</accession>
    <name>X0B0E2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980053">
        <property type="protein sequence ID" value="EXK75595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B0E2"/>
    <dbReference type="HOGENOM" id="CLU_080483_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="22"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="301" mass="34510" checksum="24C08A5023963184" modified="2014-05-14" version="1">MRGAEAAAQDLVSSRNMSLRTWADIMLWRHGGRFARHHIFAFLVFNMSVRSRNRRVSMLSVTRKNFCKIERIVRSLSADRLAAARIELENSGKTTDEGVKELLRSLSLYGFRQPMSRESRLSMRRKIQSLILRHGVPAIWFTLNPNDITNPVKLRLAAYRTSEPDAAEAFLRSLDMSYKRLRLAISDPMSSAIFFHREMTLFFEHYVKVGEESVFGRIIHFFGAVETNERGALHVHGLLWLHGNAHLSSMITDIDGEDQAMYRERIIQYIDSVFSEVQYGPRHVIEDAAVEAGAKADIPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0B0Q4</accession>
    <name>X0B0Q4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-asparaginase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_19574</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979953">
        <property type="protein sequence ID" value="EXK75660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B0Q4"/>
    <dbReference type="HOGENOM" id="CLU_752356_0_0_1"/>
    <dbReference type="OrthoDB" id="5091939at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="entry name" value="L-asparaginase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707:SF28">
        <property type="entry name" value="60 KDA LYSOPHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500176">
        <property type="entry name" value="L_ASNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936635" description="L-asparaginase N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="27"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="L-asparaginase N-terminal" evidence="4">
        <location>
            <begin position="57"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="active site" description="O-isoaspartyl threonine intermediate" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK75660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="316" mass="34732" checksum="519845CC7B731509" modified="2014-05-14" version="1">MSLISSQKLMLIVAFFIATFFAVLQTAPITPPYIKTNPTAPESTALNEPPESPKPTVAVLATGGTALGKGGSPTDTSHYISGASHIDSVIDLIRLDFQEIAHVVTHQILSTDSINFHAKELITIRNGIIEYLRRPEISGVVVVTGTTTMHIVARFIEHTIPLFNKTIALTGAIKPLTAYGADGPGHILSAIHTVATRCLNRVVILMENKIMLPRRSYKHHNTFVPGDGSLLGSVVNFRPEIFNAPRDIPKTFDIQGLEAHDKIPRTKYFHPMMEEEEFDRAIKEGVEAAVLGVYDDGYFPERLTNGLKKLTDQTQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1F3</accession>
    <name>X0B1F3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19653</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980079">
        <property type="protein sequence ID" value="EXK75581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1F3"/>
    <dbReference type="HOGENOM" id="CLU_3050413_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="54" mass="6330" checksum="42E857A727974495" modified="2014-05-14" version="1">MRYFPQSLRWQASFIFTPNLARLNELQAMDILTEPSMEYRHSTVMSIPSLVAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0B556</accession>
    <name>X0B556_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_18052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979403">
        <property type="protein sequence ID" value="EXK77230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B556"/>
    <dbReference type="HOGENOM" id="CLU_024934_0_4_1"/>
    <dbReference type="OrthoDB" id="3546279at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF7">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK77230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="368" mass="41566" checksum="6E50762BCE870D1D" modified="2014-05-14" version="1">MVNGGGAKSRRAHKKAKTGCLDCRRRRVKCSEEKPECRACCRRGVECQYPSFQARSLSAGHSPATQHGDETSPDSTRTLTQRLNQGQHISPIPILASLSCPAILRQSREQSSATFGIEDMALLHHWTVSTSLDVYKNSGVSITCQVTFPQIAFKHPFVMQALLGLTALHVAYLDPQERLKYTADAARYHNQGLQGFNEAIHMANDELADALFVWFSLNLLYVFGVSGRLGEGFWVESGWGSRKDRILGTGWIPMVRGILAILSPSFSTLRAGPLRELLSVGNFDDMDPDKIMNPDDQRFCQTRHVWKNNPDAPIYEKTLWFLRQCRMFMAQFSTMDVEDHSEAEFNRAWQGAFLFVPFVPEEYFSLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B566</accession>
    <name>X0B566_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658628">
        <property type="protein sequence ID" value="EXK77245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B566"/>
    <dbReference type="HOGENOM" id="CLU_059402_2_0_1"/>
    <dbReference type="OrthoDB" id="2873061at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587:SF4">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="124" mass="13850" checksum="D870E9119B6DD916" modified="2014-05-14" version="1">MSSMEKGRVSSQDMESESSEEQPQEVQRQGKKRSNIARRQSRQQQQQQPGPLEQVPVPGDVSNNVDNLRDDTNTLGNMSNNAVQQQSGDDGGENDALRLRLDLNLDIEIQLKARIHGDLELALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5J1</accession>
    <name>X0B5J1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658651">
        <property type="protein sequence ID" value="EXK77031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5J1"/>
    <dbReference type="HOGENOM" id="CLU_1124597_0_0_1"/>
    <dbReference type="OrthoDB" id="4976063at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="247" mass="28850" checksum="4BC6D640B869C0D5" modified="2014-05-14" version="1">MGSNPGWGMLKPEQTEPFIASSPQWKLVGESCYEKVEPFKYETNDADTERHQLSSLFTIRYTMNTKTKERSVIVDLISPNLQFMMEKALYGVETADFREPVTLVNFKTLFHKRTQLRMFRDVHSHHITAFLLDKEHFRCFIRIFEDLCEDLDNRLEALVRCDEITWEFLPELFLPKTKVLRNDGTNDIQEEGTCLDCEETIDKEGLRFIRLGISLDQGGDCSIFIPEFDSKVAIRSLEVYPKDIMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0B730</accession>
    <name>X0B730_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658591">
        <property type="protein sequence ID" value="EXK77581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B730"/>
    <dbReference type="HOGENOM" id="CLU_1310183_0_0_1"/>
    <dbReference type="OrthoDB" id="5106381at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="175" mass="19402" checksum="440DB8B9E397DAD0" modified="2014-05-14" version="1">MSTLSLSAEPYRPVQDYHQQQQQPQHPPQQQHAQQHPPPPPSPAHPTDYRYPLYGPRDPPVKRGRTEDGHQPNSTGHASEGMLSTPHHPPTSLPPPPPGAYPNNPPRHMNYEGAPSMPPTLGDYRAPSFLPPTSIPHQTPYEQHGGYPSISHEPFYSVYSSSSPAKKKNNRASQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BA90</accession>
    <name>X0BA90_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658483">
        <property type="protein sequence ID" value="EXK79085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BA90"/>
    <dbReference type="eggNOG" id="ENOG502S685">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110797_0_0_1"/>
    <dbReference type="OrthoDB" id="3260716at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="190" mass="20321" checksum="CEE612B9B5087555" modified="2014-05-14" version="1">MAAKNPDSLVGEGPFHARINPAQPAANNWHKPGNEQGNDAVPEYHAETFPPGTAPAENTFHPNPDSNYTTEALNMPALDMPGSTSKEVHKSIDNLHGKPLIGQENREIRGVHPGKRKKERSGLEGVGASTTYSVFDKVRDTVADKPNVEKGQRGYSGKREGGLAADGAESMPPVTADERAVREGPHKSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBF3</accession>
    <name>X0BBF3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_16269</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979351">
        <property type="protein sequence ID" value="EXK79106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBF3"/>
    <dbReference type="eggNOG" id="KOG1212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF2">
        <property type="entry name" value="AMIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="5">
        <location>
            <begin position="69"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="3">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="220"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK79106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="549" mass="61158" checksum="333D1EF61A1A6451" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBL1</accession>
    <name>X0BBL1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979734">
        <property type="protein sequence ID" value="EXK75894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBL1"/>
    <dbReference type="HOGENOM" id="CLU_2996589_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="57" mass="6338" checksum="A0F5B021F961B0D3" modified="2014-05-14" version="1">MLLPRFVMTWPNRKRQISAIGLHSASRTPMGSLSVSFRPETSTTSTPSFSTRIGILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBU1</accession>
    <name>X0BBU1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979671">
        <property type="protein sequence ID" value="EXK75979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBU1"/>
    <dbReference type="HOGENOM" id="CLU_2333702_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="98" mass="11257" checksum="C530E1E8AA5252D0" modified="2014-05-14" version="1">MQEIVLLSRWRVLACGTTFHPLLSKALATTPTVTKARSGSDMLQLRRRLVQRLFSVFGYLHLPKILKTQLPTSRKEFLYKTRSILGRVKLSLRGNLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC26</accession>
    <name>X0BC26_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658772">
        <property type="protein sequence ID" value="EXK76064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC26"/>
    <dbReference type="HOGENOM" id="CLU_3175417_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="47" mass="4748" checksum="31CE43EEF02E31A2" modified="2014-05-14" version="1">MAVPVIGAAAVSARISMAGKSAVSPGIGLETVPALDLLPIVRQFCRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCC6</accession>
    <name>X0BCC6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_18789</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JH658714">
        <property type="protein sequence ID" value="EXK76473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCC6"/>
    <dbReference type="ESTHER" id="fusox-x0bcc6">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_6_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000213">
        <property type="entry name" value="Carboxylic ester hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152087" description="Carboxylic ester hydrolase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="9">
        <location>
            <begin position="33"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK76473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="571" mass="61733" checksum="9D37B68069E46CC1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCT0</accession>
    <name>X0BCT0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_18635</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979472">
        <property type="protein sequence ID" value="EXK76628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCT0"/>
    <dbReference type="HOGENOM" id="CLU_000604_35_2_1"/>
    <dbReference type="OrthoDB" id="5099253at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter family G" evidence="8">
        <location>
            <begin position="99"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="7">
        <location>
            <begin position="220"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF19055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK76628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="344" mass="38282" checksum="B456B0A4340752A8" modified="2014-05-14" version="1">MLRQPHDVTKAQKLEFVEETVHLLGMGGFADAIVGLPGHGLTAEQRKRLRIGVELAGKPSLLLFLDEPTLGLDSQSSEAILTLLQKLAAGGLGILCTIHQPSAMLFQRFDRLLLMARGCKVAYFGDIGENSETVLEYFGERAPRRCNDAENPAEYLLDMIGNTSGHGFDWPCLWDKSTEANQVSTELERIVQSSSPKTSHGIDVVQVRQRGAYQVPLASQLPIVFMRILQQYGRSTTYITSKFRLAIAGTLFIGFSFFQPGQSILGIQNAIFSILMVCAMFSSLVQQIMPKFVIQRTIYEVREQHSKMYSWIALISANILVEIPYHIALGVITFAIFNYTVFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDF4</accession>
    <name>X0BDF4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979491">
        <property type="protein sequence ID" value="EXK76529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDF4"/>
    <dbReference type="HOGENOM" id="CLU_012494_6_1_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="87"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="316" mass="34484" checksum="238E13BA0EAFDAAA" modified="2014-05-14" version="1">MGLEMDQEFITKLGPFLQTLKDVPRPEVHDIEGRRARYAGMEGLPPIIPQGVTFEIIHIPTTDGATLPMYHFRKDNSVSSEDLSAAVIHAHGGGLITLSPAVSVGRLAEIVSDTGVQAFSVDYRLAPEHPYPAALDDCWTCLTWIHSNHRNLHVDPKRIAVMGESAGGCLAAALAIRARDAKLSPPIAHQILSSPMLDDRTNAEVPGDLQLWDAVDNLTAWTAYLQKTPGGDDVPALAAPGRLEDASGLPPLYLDTSQFDLFVRENLNYVQKFIDGGVKTECHLYPGLPHGFDGILPNHSVSQALEENRKRILKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE56</accession>
    <name>X0BE56_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_18176</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979417">
        <property type="protein sequence ID" value="EXK77103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE56"/>
    <dbReference type="eggNOG" id="KOG0320">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047143_0_0_1"/>
    <dbReference type="OrthoDB" id="4842715at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33481:SF1">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33481">
        <property type="entry name" value="REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="457"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="241"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="344"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="255"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="344"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK77103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="59333" checksum="32927CFE763CC2B2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFM6</accession>
    <name>X0BFM6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658440">
        <property type="protein sequence ID" value="EXK80611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFM6"/>
    <dbReference type="HOGENOM" id="CLU_1981650_0_0_1"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF10">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="48"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="126" mass="13228" checksum="807E80E644C99DF9" modified="2014-05-14" version="1">MATEEATFRNYTQAQGESYATGRPGYPPELFEIILNHHTSTGGRLDTVLDVGCGTGQATRDLAPFFKNAIGIDPSEGMITSARETIKSSALSTRFDVSAAEALGIGLEPPIANDSVDLLTAATAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFR1</accession>
    <name>X0BFR1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658439">
        <property type="protein sequence ID" value="EXK80646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFR1"/>
    <dbReference type="HOGENOM" id="CLU_1758898_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="148" mass="16873" checksum="73C0066AFCBC6546" modified="2014-05-14" version="1">MSRQDVIGKLRRIINAGKSQLKLENSREDQLHLDREKPSSPLGPPSLKKCHEKQPASAQEEYEAECSCCGDLYTGLRIAQNHIRFIQEDIDHIATDIGTVVKAMEKSHKNPSKANTENAMEEIKGICKRLRDLQDDIKYRTKEVTRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFR9</accession>
    <name>X0BFR9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658623">
        <property type="protein sequence ID" value="EXK77319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFR9"/>
    <dbReference type="HOGENOM" id="CLU_2223431_0_0_1"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="106" mass="12197" checksum="B63FB8615E6CC171" modified="2014-05-14" version="1">MDGIQDQQLTDLTLEDLQKQAKDLDLRTDDGMKSLLNWVWDIIKGFCLYALGSEDSPEAGSLPHVEWTHPELVRRSFELAGSSRERQPLILWIIELRQLIPSEAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BG04</accession>
    <name>X0BG04_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979389">
        <property type="protein sequence ID" value="EXK77419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BG04"/>
    <dbReference type="HOGENOM" id="CLU_1555336_0_0_1"/>
    <dbReference type="OrthoDB" id="5099221at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="172" mass="19746" checksum="B82F72B62F58B4B7" modified="2014-05-14" version="1">MHPVEDDESSHASSDESDGETDFEGDTNLGVEIGSQYQFEFLFPSRPWLEPSEALFQLSMMFWTHQDPAGDMSSSVIIYYTAVMGIQRRSMSYYPAHSSTSGLAALMWIGRALFLEYALPLYSYATLAYHWPSRDQYHSQPERLEVIRQRYLVLSALNKSSQDKPELWLVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIC0</accession>
    <name>X0BIC0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_17142</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658538">
        <property type="protein sequence ID" value="EXK78174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIC0"/>
    <dbReference type="HOGENOM" id="CLU_005230_0_2_1"/>
    <dbReference type="OrthoDB" id="10264220at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026028">
        <property type="entry name" value="V-type_ATPase_116kDa_su_euka"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001293">
        <property type="entry name" value="ATP6V0A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="548"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="586"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="641"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="771"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK78174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="843" mass="96464" checksum="6A4A0A5930952168" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-03-27" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIY6</accession>
    <name>X0BIY6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658520">
        <property type="protein sequence ID" value="EXK78429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIY6"/>
    <dbReference type="HOGENOM" id="CLU_183181_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="34"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="73" mass="8395" checksum="6E4925E4BB76E2DF" modified="2014-05-14" version="1">MRFRVVLSLMSLDERIKAAGEKEQEAIRLSDIANDHISLSRRRAEKKVKELESELESLKADLKNLEKEEADAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIZ9</accession>
    <name>X0BIZ9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16504</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658499">
        <property type="protein sequence ID" value="EXK78838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIZ9"/>
    <dbReference type="eggNOG" id="ENOG502RMCK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158096_0_0_1"/>
    <dbReference type="OrthoDB" id="3748548at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.270.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="140" mass="15312" checksum="4422A285C196D09B" modified="2014-05-14" version="1">MATRELLVIILNHTNEELNIEPQSPSLDHGHWIDTPDSRPPQMILAGESGMLRCKSSHIGGGIEGSITYRVVGFDANNKVTFLWNVPYVGPNKFDCSCAIDAFTVKVLGGRGNQAVVVFVFERALRTDPRLDDGVFAAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-03-27" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJJ9</accession>
    <name>X0BJJ9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658512">
        <property type="protein sequence ID" value="EXK78634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJJ9"/>
    <dbReference type="HOGENOM" id="CLU_2084950_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="85"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="117" mass="13176" checksum="00AB3CA64D5ED4AA" modified="2014-05-14" version="1">MHYFPNLPGHIANLNHTTGRLLRDMSAPPSPSGYRPPQGAEETLSQQLVSKAIMLATVQVQRLRHQHLTVGVGENKEDLKPRHFLAELKQARQGLIDQLNSTTKKLRRKIVKLEGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKA0</accession>
    <name>X0BKA0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658495">
        <property type="protein sequence ID" value="EXK78889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKA0"/>
    <dbReference type="HOGENOM" id="CLU_126111_0_0_1"/>
    <dbReference type="OrthoDB" id="5032760at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="145" mass="16464" checksum="75C3F9C4B1C5EA74" modified="2014-05-14" version="1">MYEKQLPSLPPQSPQDQVSPRAVVAPFQSPSQRHPLGHISQQAQPGGGILTSLKQEILKLRRENDALRRSMVEKENKIEMLQKLNSQHRQRMDEQTRQTSQLFQTIHSALKNYRDDKKDQAGHLPKGSSEEIVSGAFSDRGEGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BN07</accession>
    <name>X0BN07_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HotDog ACOT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12558</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658405">
        <property type="protein sequence ID" value="EXK83206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BN07"/>
    <dbReference type="eggNOG" id="KOG2763">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032862_1_0_1"/>
    <dbReference type="OrthoDB" id="331699at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03442">
        <property type="entry name" value="BFIT_BACH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000032">
        <property type="entry name" value="Acyl-CoA thioester hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000038">
        <property type="entry name" value="Acyl-CoA thioester hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655:SF0">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="6">
        <location>
            <begin position="97"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="HotDog ACOT-type" evidence="6">
        <location>
            <begin position="294"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="449"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="451"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK83206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="475" mass="53195" checksum="4BD32F7355C78A33" modified="2014-05-14" version="1">MMSRSREARSIVASLRRPHVLRPANPALARPNANSFHTTTPRKTDGVFQGLEDKRQPMPWIEAFERQQQGLPAHKSDDYPKERDLTPKKMSDSYHRVVLPLKKDPWLSDTYVNSSGHIRLGTLFMDLDALSGIIVYKHTGPGVTTVTAALDRITIAHPLTEICDLEYSGQVTYASGRSSVEITCKVAKAREEGEPSKPEDVLLTCTFTMVALDPNTRKPVNIPKLVPTNAEEEKIFKAGEAKSLSKKENSKASLLQTEPNDAESALIHQIWLRQLAYHDPNNDLRQPSNVVAMSKTQLSTAAIMQPQYRNRHQTMIFGGFHLKQTFELAFCCAASFAHARPTFISADPCTFRNPVPVGSVLYLTATVAYTDPPLLEEDGTEPGFPDPEKPMTRVHVRVDSKVRDVEHGVAKPTGQFNYTFSVPKDLKVLPHTYEEYMVYIDARRRVSLGDSQRKEESKAFSEKRPEATDNVNLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP87</accession>
    <name>X0BP87_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14826</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658438">
        <property type="protein sequence ID" value="EXK80693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP87"/>
    <dbReference type="eggNOG" id="ENOG502RMJX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029465_1_0_1"/>
    <dbReference type="OrthoDB" id="5419315at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="546" mass="62679" checksum="A2660CBE3BC3696D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPE2</accession>
    <name>X0BPE2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502SA0I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001373_1_0_1"/>
    <dbReference type="OrthoDB" id="5288142at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="756"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="857"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1067"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="899"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="911"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="924"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="952"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1093"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1174"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1200"/>
            <end position="1211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1410" mass="153232" checksum="09C0281CA6E8837D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRP6</accession>
    <name>X0BRP6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRP6"/>
    <dbReference type="HOGENOM" id="CLU_3014174_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="56" mass="6512" checksum="C71CA02B087E8750" modified="2014-05-14" version="1">MIDRLAYGEKQRALADDWALVREKRCGVVSMTVCTREVRQRRLKTPMIVSTKMLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSA3</accession>
    <name>X0BSA3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_10996</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSA3"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_3_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000090">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF72">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="15"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK85060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="518" mass="58090" checksum="CA2B1C266B46C155" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSQ5</accession>
    <name>X0BSQ5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">25-hydroxycholesterol 7-alpha-hydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_13616</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK81968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSQ5"/>
    <dbReference type="eggNOG" id="KOG0684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018012_2_1_1"/>
    <dbReference type="OrthoDB" id="3366823at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="466"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="479"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="512"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="64720" checksum="FB91D35260A3991A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSS9</accession>
    <name>X0BSS9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">IgE-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSS9"/>
    <dbReference type="eggNOG" id="ENOG502R7AW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086095_0_0_1"/>
    <dbReference type="OrthoDB" id="5100830at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936651" description="IgE-binding protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="31961" checksum="CE041C501E70F187" modified="2014-05-14" version="1">MRFAAFLSLGLGANIAIASVCKPRSRTLSDSSSVSTEPVPASSTESDAVSTTSTNIVTTTTTSVELSISATSTDDDKTSTKATESGSASVELSASTATETTTAAISTTTAETTATAETTTSAEASTTYMTTTTEDTFVPIPTFDLKALGSAVDGQWLRGDPVQYAYIGWYTPSPPILTFSIEAGTNYVREINTGKYLCVSFGGDGFPPANMLWDPINPLSGLVPLTCEQTRDRKLKCSAPAGECHMDEMSGDSVCYSIPGTWDKFYMIPDRLANSPALVMASDSNPPTIGGLEAIELQLFPHAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUV0</accession>
    <name>X0BUV0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CBM6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_12957</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUV0"/>
    <dbReference type="eggNOG" id="ENOG502SHWK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009397_11_2_1"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04084">
        <property type="entry name" value="CBM6_xylanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18618">
        <property type="entry name" value="GH43_Xsa43E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CBM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006584">
        <property type="entry name" value="Cellulose-bd_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052176">
        <property type="entry name" value="Glycosyl_Hydrlase_43_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772:SF2">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00606">
        <property type="entry name" value="CBD_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938874" description="CBM6 domain-containing protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="10">
        <location>
            <begin position="324"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="7">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK82683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="449" mass="49226" checksum="2828822B14E63DB1" modified="2014-05-14" version="1">MWLTTPLLLVSTLLGFSGVAVADNPIVQDIYTADPAPMVYNGRVYLFTGHDNDGSTDFNMTDWRLFSSADMVNWQHHGVPMSLKTFSWANSRAWAGQVVARNGKFYFYVPVRNAKTGGMAIGVGVSTNILGPYTDALGKPLVENNEIDPTVYIDTDGQAYLYWGNPGLYYVKLNQDMLSYSGSINKVQLTTAGFGSRPNNAQRPTTFEEGPWLYKRGNLYYMIYAANCCSEDIRYSTGPSATGPWTYRGVVMNKEGRSFTNHPGIIDFENNSYFFYHNGALTGGSGYTRSVAVESFKYGSDGLIPEIKMTTQGPAQVKSLNPYVKQEAETMAWSEGIETEVCSEGGLNVAFINNGDYIKVKGVDFGSTGAKTFSARVASNSSGGKIELRLGSKTGKLVGTCTVTTTGNWQTYKTVECPVSGATGTSDLFLVFTGTTSDYLFNFNWWQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVQ8</accession>
    <name>X0BVQ8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09943</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVQ8"/>
    <dbReference type="eggNOG" id="ENOG502S67X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041445_0_0_1"/>
    <dbReference type="OrthoDB" id="3205825at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="43900" checksum="130FE02092DA9355" modified="2014-05-14" version="1">MKGGGLLIPPWFEYHEPSCSDWAIVSIAFGMTLCLAIFGLIRVGIQTYHQWKRAQRITTYMVLIWLELVSSAIIGGLGWGYVRGTIRPGFLIYFFILLLWVFQIHCIMQIIVNRIALLHVSPTIVRRLKWGIFIILALINISVFCIWIPARLQISQTYIDINNIWDRIEKGIFAVIDLALNFYFVYLVRSSLISYGLTKYVVLYRFNLVMVVVSISMDILIIGSMSLRNTFLYVEFHPLAYLVKLHIELSMAELIAKIVKASGPNLAPCRCTCHDNPKHTFLHQLQSRYSAPAAPSVTAPTTGRFRRSWPMSKTTRSREKRRGGSRSQTPSLTKKMVSKKQQSTEENQPKQEVWKSDTNTGTDCASHHMPSSTGQSNESSHDHND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWS5</accession>
    <name>X0BWS5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcium channel YVC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_09490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWS5"/>
    <dbReference type="eggNOG" id="ENOG502QT9R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009570_0_0_1"/>
    <dbReference type="OrthoDB" id="2373987at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF1">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="450"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="3">
        <location>
            <begin position="52"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="270"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK86625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="737" mass="84234" checksum="753A06BE08679479" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWX0</accession>
    <name>X0BWX0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWX0"/>
    <dbReference type="HOGENOM" id="CLU_719694_0_0_1"/>
    <dbReference type="OrthoDB" id="5085789at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="384" mass="43174" checksum="FF44CCF7F9E5718B" modified="2014-05-14" version="1">MPYLQSPVPAYMELQASPPTPKATDTEQLADSQPTDSVCMESVWPFSKARVANDQWFSQVTDNDVCADASPISYLSDECNHCGCSDFDDDRAPRLEDMEFGRSERSLSKFGDLEDDVSFNSSQSIITRSLGSLIRPEHIPEVPGTPKLSGSPYRADHDGTHSTAIAMNFQGLEALCMLQLCMIIHSAVSTRKPNIGLNRRIASKSTKSCSPVQNTIRTTTHGIAGTNGSQVQRINMRTSSRKRKFETRLSNKDDSRSKKTKRSKRTTSRASFHLMALHLKDADSPPAQDREWKYEWNNKFKAWVADRAPEGYQLMSGEELYMFSQDLTFQVRPNSDWLPVYMKWHGDAFKASDSLESDWQFTIADDVMQLMLISNIAGEGTVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZE2</accession>
    <name>X0BZE2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-arginine deiminase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979718">
        <property type="protein sequence ID" value="EXK75907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZE2"/>
    <dbReference type="eggNOG" id="ENOG502QVJA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_924495_0_0_1"/>
    <dbReference type="OrthoDB" id="5102063at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004668">
        <property type="term" value="F:protein-arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004303">
        <property type="entry name" value="PAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013530">
        <property type="entry name" value="PAD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036556">
        <property type="entry name" value="PAD_central_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10837">
        <property type="entry name" value="PEPTIDYLARGININE DEIMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10837:SF8">
        <property type="entry name" value="PROTEIN-ARGININE DEIMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03068">
        <property type="entry name" value="PAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110083">
        <property type="entry name" value="Peptidylarginine deiminase Pad4, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein-arginine deiminase C-terminal" evidence="1">
        <location>
            <begin position="198"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="301" mass="33046" checksum="85C5AFB21B44F8E7" modified="2014-05-14" version="1">MRTGWLYPIFIGTHVSAGLIKSTTRPLILADTNRDGIVNGKDIADKYTWTNECGAIFLPNIGDKRHRCTAFDLNGLSLSNQELSSCNDASGHLLLTPELAAPARTAPLQGISKEAIGSIYTLPESTLGSVRVFWKQPGFLSDAGSPWRLIDPQFVFNASSLRAGIELAIDARELVSHLSAWNGTLSLEFRVTDGNMTTYDAVAMKQAPVLFHHHLQRVQEVLSVKGNETSSPVQNKFVRGLEDALMNVVETPALHLLNGTDEIWAQDFMEPGFAMRNLPELLDVRSSKASEVIESEAINCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0D1</accession>
    <name>X0C0D1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sortilin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979559">
        <property type="protein sequence ID" value="EXK76247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0D1"/>
    <dbReference type="HOGENOM" id="CLU_058803_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010411">
        <property type="term" value="P:xyloglucan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031778">
        <property type="entry name" value="Sortilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052025">
        <property type="entry name" value="Xyloglucanase_GH74"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43739:SF5">
        <property type="entry name" value="EXO-ALPHA-SIALIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43739">
        <property type="entry name" value="XYLOGLUCANASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15902">
        <property type="entry name" value="Sortilin-Vps10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Sortilin N-terminal" evidence="2">
        <location>
            <begin position="67"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="352" mass="38815" checksum="9BDFB613E35609CC" modified="2014-05-14" version="1">MLESTNIYAGVCSSNYAKLDRSGKIGVFVRAAKDGEWKHALDSVQAFKILVHPDNPEVVLVGTNDGVWRSTDRGVSFKQTDFPDTKKEIWSFLVDKRDPKRILAGAAPVEVYSSDDMGASWRKLSTPKTPEHIKSPFATRLMQFAQHPQRPDEIFAALEINGVIHSADGGETWTDRSDHLIKLAQLPHLRDEIFSGNVAEGMLDAHSIAINPNHPDDVIVALRTGLFHTEDQGRTWQNLEVGRFAPTTTYAHDIQVSSSEPAALYAALSISATSHEGGLYCSLDRGRTWQRFDKVQVNGTIMALTLHAHDPAQAYICGRHDGEVFGTQDGGETWQAMPLPGEVQHTFTISCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0K0</accession>
    <name>X0C0K0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CMGC protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0K0"/>
    <dbReference type="eggNOG" id="KOG0593">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_306751_0_0_1"/>
    <dbReference type="OrthoDB" id="3548654at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="179"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="964" mass="106937" checksum="6A22C29245C48F15" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0K7</accession>
    <name>X0C0K7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11553</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0K7"/>
    <dbReference type="HOGENOM" id="CLU_023417_3_0_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF7">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="508" mass="58353" checksum="79CBC8A1533B7CE0" modified="2014-05-14" version="1">MTIQASETYENITAYLIMPDAKLRAKTGCVTCRQRRVKCDEGKPSCHNCSRFGRSCSWPNATDMADKRHRRRRATPAPSSPANESTSPPKTDEISHDVVPILNNRASLTAINHPLLETETEFELMHHFYNFHFNSLTLPTKDKSYFFQCQSDLMDMMSHNRTVKYAILANCASNKHVLMNNDRYRLIALRYYTEAMRGLNQELVDFCPSDAYRHSCLLTVASYLYVYNFWSLDAMSNPKPHVVGAVKLLSLRNQDNSSLRPFTQSYDRINVESVLYQGFLLSIRRPFRPDFRLDSEFITHAEDLLQSYDNANPSHANPSIVLGVPTSLYRLILRIIDSYTVPRGNLSDHLKGLKAELQYWEQLLFDDENSQNVQHGDSRFNDLMIIATSLLLDLITETLTSIDDTICPAPSAGDRDGKPWRWQLDLAMNILQCPEEHQKWSGCYLGAWPLLILGYGARSLEEITLVKNVLVRMQQRIGYGEVQRIRDELDEITTYKGSKVWVRQEIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C245</accession>
    <name>X0C245_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_10874</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C245"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_3_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="10"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="7">
        <location>
            <begin position="430"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK85223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="595" mass="66027" checksum="72DB56D30425E065" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C254</accession>
    <name>X0C254_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_18398</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="JH658671">
        <property type="protein sequence ID" value="EXK76877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C254"/>
    <dbReference type="HOGENOM" id="CLU_078014_0_0_1"/>
    <dbReference type="OrthoDB" id="4995012at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="179"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK76877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="310" mass="35413" checksum="7D5E04E819490962" modified="2014-05-14" version="1">MARKRTARGQSRFDQLSRIFKAKAITDSALTQKQSNFRGKRSFPIDVSPLLVLASLNATESAISHSMAQRIDEQTEAARDMSMRGESTEVAQPSRFGPDVTCFALRHHNLNGGVPSMLKGEIEGGMDLKHLGSKKQQTNLVKRKDPTKPEGPGEPVDAGNTAELAESEGQRDDAEEPRYEVEEIISHRIKNKTEVELEARWNGCSKPTYVDERTIQEDYPLVLYTYWELRGGREEATGINLFHVFQIRRWKVKDEKLQLLVQWVGYPPKDSTWELAWRVEKFATEMHGAYLKTHRAARSVWEKEESKTRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2G2</accession>
    <name>X0C2G2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBM-cenC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10706</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2G2"/>
    <dbReference type="eggNOG" id="ENOG502RKPZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_700275_0_0_1"/>
    <dbReference type="OrthoDB" id="5106681at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937333" description="CBM-cenC domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="46150" checksum="81D46E83C03D1017" modified="2014-05-14" version="1">MTAKTIMTAFLAALLLAGSEAGPCKPRPRTTNILTTVEIMSSSTKATSTTEAGLSTTDVSSTGYLIFTTDQSESTSETSTESKDTTTTSAPVISTTETSSSLALTSSVIESSVEPNTTTEDAMTTAVSITSTAEISSTIIESRTDTSTISEDTTTTIIAVLTTKVSLTKELTSEMIESCTEESTTIEASFTTTLSTSAPELSPTVIKSSTGVSTVTEDVTTTTISALETSSAVDISSTIVESSTEITTSSQEPTATVSISTTVLIPTTTESTTTSEVTTTTTTEAAGPPTLVNLGFDDTTEPWSVTQPNLVSLSLDNNIKHDGRSSARMSFSTAGGSTSYISQAYSSPAQAGVGYPASAWVRPGPGCTIAVLGCAYGNAGLFSGRRTLVVTATTTQPGTINQWQEISYTCTYTQSQIDQGGLALNIGFMCISGSEAWIDSVIFSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C352</accession>
    <name>X0C352_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10857</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C352"/>
    <dbReference type="eggNOG" id="ENOG502SSAT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071361_0_0_1"/>
    <dbReference type="OrthoDB" id="4364812at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="299" mass="34501" checksum="B7C485B5A7D4A61D" modified="2014-05-14" version="1">MSQFQENIYPRWGSLAIEQYLLKKWDSTSTLSVCQQRDQLIQAFLHEDDVSGFASSILDATSNHVQELIQTAIAPWRSQHLRRIAEKYLPGNDLYGKLVVLRTHYGGVSDDVKFRHWIYDAATAFAEDNPLGDLFGDSEDHWWRILDDASLFDTGDQDWESIYNRFPELASPEVCRTFSDGDVAEVKEEVSAVVTSREPEEDDYEDAIAHAAVSGCWLLVLDRESFEDEEMLLVFRDRMGNVVRQSSIKPEDLEHIPHYIMRGSITESGFWRDAEIGKKYKWKGKIMREILPRVMAEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3R1</accession>
    <name>X0C3R1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_10236</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3R1"/>
    <dbReference type="eggNOG" id="ENOG502SA5Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056998">
        <property type="entry name" value="Asd-4/GZF3_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF338">
        <property type="entry name" value="GATA-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25026">
        <property type="entry name" value="Asd-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="84"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="139"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="340"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="457"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK85803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="501" mass="52915" checksum="09DB5CA40E96D26B" modified="2014-05-14" version="1">MEEDGAQLLQQTGLDPISRPDSTSTSASASLPHVLPGISALAAANAATEATSQLRASAAPSPAMYATASPAATSGGSGSTMPTCQNCSTSTTPLWRRDEFGSVLCNACGLFLKLHGRPRPISLKTDVIKSRNRVKTMRPDLANKKKQQQQQQQAAAQGFPTTDANGFDTTGQAAAAAAHAAQAARRASQRSNGHDGADSPISRTGTPSMYAHGLSQFMVDDPYQTGFVATGEGRASSPTNGDRKMDAPQTHEQLIAHNSSLKTRVSELEVIIELFRGRLSQLEQQEAVVRSGQQLNQLRSQLEQTQESEAQLRRQLEDSHRRESSLKRRLDELELELQAFQEANSAPGERPAKRPRTIEEPTKTQAEADIEAAAEALLASEASRPSEAVESAPVVDAPEPTELPQHPESSKEGSVPKTEDEIEAADVPIDPNMPVIDDVSQPAATEETTKTEDVEIPDAPDASEAPGAPEAAEAADAAATADASPEATEGTETPAPATAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3S0</accession>
    <name>X0C3S0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Multidrug resistance-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_10244</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000055">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000066">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001854">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF345">
        <property type="entry name" value="ABC MULTIDRUG TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="515"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="879"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="928"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1028"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1116"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1142"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="274"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="595"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="893"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1206"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="823"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="839"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK85813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1473" mass="162192" checksum="1C25D720A959D22F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4I1</accession>
    <name>X0C4I1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-glucoronosyl and UDP-glucosyl transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4I1"/>
    <dbReference type="eggNOG" id="KOG1192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036519_2_0_1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK86098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="60946" checksum="77031CB07C52B52E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C510</accession>
    <name>X0C510_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GPI inositol-deacylase winged helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658566">
        <property type="protein sequence ID" value="EXK77847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C510"/>
    <dbReference type="HOGENOM" id="CLU_083068_0_0_1"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="1">
        <location>
            <begin position="7"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="292" mass="32861" checksum="3A539452ACAB8E2C" modified="2014-05-14" version="1">MLKNIPAEYKSSAIRLLQFLVYTKRPLTLAEAIEVIATEIDQEPQGFDVDGRLSLKADVLRYCPSLVIIAKVTNYTETVEELHLAHFSVKEYLLEQAQFDLESASIVITRTCLTYLGDIENNCSTIRSDFPMARYAAKSWMDYAASAETSEEIVRITVSFLRNETTFQRWCRLYQADRAWDRTPGPPRAPRLYYACLGGLARAARDLAIEGADVNAQGDEYGNALQAASYNGNREMLCNCSSTKEPMSTTLNIYILTNWKTSTGIWLSSKNQELCIIKHWKAACRDLGGHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6H7</accession>
    <name>X0C6H7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6H7"/>
    <dbReference type="SMR" id="X0C6H7"/>
    <dbReference type="eggNOG" id="KOG1379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029404_1_0_1"/>
    <dbReference type="OrthoDB" id="25675at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000118">
        <property type="entry name" value="Phosphatase 2C-like domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF24">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="87"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="381" mass="42009" checksum="7DEAE3886D81D55E" modified="2014-05-14" version="1">MPSQPSSILAAVPTSFLPSLPVRRLTCTTWRPCRKRRFASTTTRLLHDVPILPFRFETGIGLFAKRPPRPFPPPFLSPPSTSFTDPLSTHHQSRDRRAFVNGQLIRGKTNGDDAVYASDYFICANDGVGAWATRPRGHAGLWSRLIGHFWSSAIEEELVRLPKSQEPNPIASLQSAYEQTLEATMSHDCLGTTTACGAQLHYKTCTENKTQASPVLYVTNVGDCQVMVLRPSTEKVIYKTVEQWHWFDCPRQLGTNSPDTPTDNAVMDKVDLEVGDIVLAMSDGVIDNLWEHEIVARILKSIKEWESGTHAEAHKGDRTGGRNGGMRVAAQDLMEAAREIAVDPFAESPFMEHAIEEGLASEGGKLDDISVVAALCVKNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7J3</accession>
    <name>X0C7J3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial import inner membrane translocase subunit TIM54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_07485</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIM54 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7J3"/>
    <dbReference type="eggNOG" id="ENOG502QPMQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039097_1_0_1"/>
    <dbReference type="OrthoDB" id="5598305at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021056">
        <property type="entry name" value="Mt_import_IM_translocase_Tim54"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11711">
        <property type="entry name" value="Tim54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="212"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="233"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK90116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="459" mass="52152" checksum="C49A77F8B6C8A298" modified="2014-05-14" version="1">MAEPNPSAQQPAAGTGATYKAPTPKPKQNPALRMMGLPNLPRKLPSRNWLIFWAITGSISAAIIYDKREKKRATAKWKHAVAPLAKDIIPSASQLPRKLTIYLEAPPGDGLRIAQDHFIEYAKPVLAASGLDWEFVQGRQQGDVRAAVAEKIRRERRKYERPDEEDLQTDEAITESLRKKNQVPEYEGVKGDIIFGRHTWKEYIRGLHEGWLGPLDPPVKPEPITKTVEADSETPKAEGDQPEEKKEGKKEEEEEKKPERPPQPLPYNTTADYSIANLPPQIPAEFSPANPIPLPHRLGFRHTLVRLNRFFNRRKLADEIGREVAAVCFANSSREWREADGQYEQELVLKHEENDWVKSVWKPEDPPKQDDDNTATVPTEPPKEKIWPAPMVIDPRLAQRMRRFEIAPEDEARAAHIKVSEAEIEGWIKGSFRSLWNYTVESVTAKPMRPNVGNVDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7V1</accession>
    <name>X0C7V1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16554</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658502">
        <property type="protein sequence ID" value="EXK78792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7V1"/>
    <dbReference type="eggNOG" id="ENOG502RK2G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1115778_0_0_1"/>
    <dbReference type="OrthoDB" id="5104412at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937423" evidence="2">
        <location>
            <begin position="19"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="249" mass="24897" checksum="3914BD8D57F69037" modified="2014-05-14" version="1">MKVTLQLITASLAVSVAAHPQNGPGGRKPSSTTTAAAASSTTAAPGRGAMSSLPFLPTWLFRDSNANKCISTYNNCLITNSSNQSACASNYAACIKGGSSTTGSATSAQTATTTVSSAGGPPTRTFSRPSVSGLAQWWRNEQSIRRCNYAYYVCRRKSGSTQTSCASDRTACIASASATGSATAAPTSIPTSIPTSAATTTATGSAATSSAVSSSTTVVPAGNGAADADAPLNSDDPSFDDANYDADTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8R3</accession>
    <name>X0C8R3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8R3"/>
    <dbReference type="HOGENOM" id="CLU_2146005_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="112" mass="13038" checksum="CB18333380F7A285" modified="2014-05-14" version="1">MFEAELREERAFRTRIDVMKLRVARIHEMCYVIDMAPTGPGNSCIMTMYIRSRRKGQRMVRGQLREIGELRGTSMGSSPHVRYRPQPKSKPKPDPDPELDPEPCMIHILLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDP7</accession>
    <name>X0CDP7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDP7"/>
    <dbReference type="eggNOG" id="ENOG502SPMP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044083_2_2_1"/>
    <dbReference type="OrthoDB" id="2119228at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF5">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012158404" description="SGNH hydrolase-type esterase domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="61"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="303" mass="33739" checksum="51EDB3B66A77A17B" modified="2014-05-14" version="1">MWYSLLACLVSAAHASTLQPREDAAQIARNVSGFTAYDVLNYTKVDSDDSWKLQVPLRILCVGDSITEGWGSDADGGDGNGYRLSLAKHLSREKVVFAGTRHKGSMEDSYYAAWSGKTIQYISDHVTESLEQKPNLVLLHAGTNDMDLRPSISKEGNDPKDAATRLGDLIDKIVRCCPDAVILVAIPLASCDTEKPKMPIYRALIPGLVRQRRKDGDHVIAVDFSTFDLGELRDCLHPTNEGYSIMGDYWYDFITQVPKGWIKEPVGDDPKREENGVGRRVLPDKMSILGIVLCWGLYRMCWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE74</accession>
    <name>X0CE74_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE74"/>
    <dbReference type="HOGENOM" id="CLU_064787_1_0_1"/>
    <dbReference type="OrthoDB" id="2687876at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="279" mass="32094" checksum="941FFDB872D206F8" modified="2014-05-14" version="1">MSDIISKQINIVPKSNIEVLNQEIDDDEGQYRIRAGNRVHYVTIPGHGSPNPIFKEDTLCRPYLLVPELPPFPDTNWTKMRLSPAEDGSVQSDISFEPLDKIKCTWHPRHIDILSLRRIKYHKQRIREVEYEGKTAISKIAILEWLIPQLEHETKMYEALTRLQSPDEDSMTPEVLGHLFEGGRNIGFLLEKIEGEYATLADLPKCEAALRRLHKLGFVHGDANRYNFIVERPTGNVKMIDFEHAEQYDEKKAKTEIEKLASELTDDSGRGAPVTFVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEB5</accession>
    <name>X0CEB5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptide hydrolase</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14499</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK80977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEB5"/>
    <dbReference type="eggNOG" id="KOG2195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024336_1_1_1"/>
    <dbReference type="OrthoDB" id="10013407at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04816">
        <property type="entry name" value="PA_SaNapH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF26">
        <property type="entry name" value="PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152167" description="Peptide hydrolase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="124"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="9">
        <location>
            <begin position="244"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK80977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="496" mass="53280" checksum="BF483462BB848019" modified="2014-05-14" version="1">MKFSTGVAILLALAPSHGLAKTHKLESKKIQADMKTKNLMSNLEAFNDIAFANGGNRAFGLPGYDASVDYIFKRISKVKNAKVWKQNFPALFAFVDSIELKVDDTPVYVYGLTYSPSTSEEGITAEIALGPEGAAGCDTSSYDDLDVKGKIVLVQRFRCPTGGTLAGRVIPAAAAGASAVIIYHDLTTNVTAGSLSQPDPEKHVPAGFINLVDGEKIKERIEAGETVTAHFQQTQTIEERITQNVIAETKGGDPRNVIMLGAHLDSVQAGPGINDDGSGSSLILELFLALSKYKTKNRIRFAWWGAEENGLLGSKHYTSTLPAKDVNDLLVYLNFDMVSKGFFGVADTDGSSHGSKAPKGSEVTEKIFTEYFESKGIEVTPAVLTNGSDYAPFWQNLNKPFGFLHTGTAVAQDPCYHQACDTIDNPDSKTLTINAKAAAHILAVLDDRGTKLIPKTKTTAASLQGLQERSVGPDLAQIDELEAMGIRHLGCGIHEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF72</accession>
    <name>X0CF72_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_07578</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF72"/>
    <dbReference type="eggNOG" id="ENOG502SM7B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010779_4_0_1"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08983">
        <property type="entry name" value="GH43_Bt3655-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046780">
        <property type="entry name" value="aBig_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20578">
        <property type="entry name" value="aBig_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939363" evidence="4">
        <location>
            <begin position="22"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Atrophied bacterial Ig" evidence="6">
        <location>
            <begin position="32"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="5">
        <location>
            <begin position="111"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK89479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="419" mass="46216" checksum="9508FC8E522913CE" modified="2014-05-14" version="1">MLPRLQSLSLALLSLATGIHSHEALSSLNVRNLEDIRSHITLPSTSNGHSITWRSSDPSIISHDGLVKRQPTTSDVLLVASLEVDGQLHEREFNASVRQAVQQDPYEAYAFSYFTGNSKQGENIYFAASKGNNALDWQELNGGQPVITSKLGTKGLRDPFVIRSVEGDKFFMIATDLSIGSGTSWGDAVRKGSLYLEIWESDDLVTWSEQRHVKVSPDNAGNTWAPEAFWDDEKNSYVVFWASSLYNTADHSDNSYHRMLYSLTRDFVTFSKAEIWQDSKTSRIDTTVLKSGNSFYRFTKDEASASGCTDIIQEKSSNLLAPVDGWTVQATCIGKNAGLQAVEGPTAFKGNAGDANGEKFYLFVDEYGGKGYVPLETSDLDKPSWKVSASYKLPTSPRHGTVIPITKKEHEKLLSAFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFV2</accession>
    <name>X0CFV2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-xylosidase C-terminal Concanavalin A-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_14044</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658426">
        <property type="protein sequence ID" value="EXK81512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFV2"/>
    <dbReference type="eggNOG" id="ENOG502RT0S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016508_1_1_1"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09001">
        <property type="entry name" value="GH43_FsAxh1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF15">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936380" description="Beta-xylosidase C-terminal Concanavalin A-like domain-containing protein" evidence="5">
        <location>
            <begin position="19"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="6">
        <location>
            <begin position="331"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK81512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="530" mass="58972" checksum="F9F52049B8A10559" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGL8</accession>
    <name>X0CGL8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_07189</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGL8"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17327">
        <property type="entry name" value="MFS_FEN2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000068">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF46">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="55"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK90393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="498" mass="55593" checksum="E4102F82EC64E432" modified="2014-05-14" version="1">MALNHTEKDEGNESPVSLDPERSHVRDAVHTDDATVVCPSSTTDTKLMTKIDLHVIPFLCIMYLLAFLDRVNIANADVFGLSEELGLEKTEYNTALVVFFVPYVLFEIPSNILLKRFKPHVWLSLNMFLFGLTTLLQGLVQNYSGLIATRFFLGLFETGMFPGAFYLIGMWYRRHEAQRRYSFFFNSTTLAGAFGGLLAAAIGKMSGMRGYAGWRWIFILEGGLTVLVSFFFYFLLPDFPEQAKWLTSEEKHYVTARLRIDQGHAGAERKTTFADALSVLKDYKIIIGGFMYFGLIVPAYGYAYFAPGIIKTYGYSPIQTQLYSVPPWAAAFGFSLAVAFASDKLRHRASFAIFAILVAIAGFAILLSVHNNHSVQYGALFLVTMGAYTAMPIIVCWFNMNLGGHRRRSIGSAWQVGFGNIGGIIAVYSFLAKDAPKFIPGYSICIAFTILSIIACLSYAAVILYENKKRDANPPQTELTNEEKAELGDNAPTYRYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHN8</accession>
    <name>X0CHN8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHN8"/>
    <dbReference type="HOGENOM" id="CLU_2263864_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="103" mass="11807" checksum="06455A24D211D137" modified="2014-05-14" version="1">MLRQQALTSIDFSTVLFDNRRYFCLFPTHPQLDQHVEHMKECFVSLRCRPVSLELPPILFKIGCSKTWVSLKPSGRVLPCISRRPFPSFSTVPNTRTPVASIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHY8</accession>
    <name>X0CHY8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">Postreplication repair E3 ubiquitin-protein ligase RAD18</fullName>
            <ecNumber evidence="5 17">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">RING-type E3 ubiquitin transferase RAD18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">FOQG_07237</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">Interacts with E2 UBC2, forming a complex with ubiquitin ligase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 17">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the RAD18 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5 17"/>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHY8"/>
    <dbReference type="eggNOG" id="KOG0287">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028491_2_0_1"/>
    <dbReference type="OrthoDB" id="9049620at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097505">
        <property type="term" value="C:Rad6-Rad18 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006301">
        <property type="term" value="P:DNA damage tolerance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000172">
        <property type="entry name" value="E3 ubiquitin-protein ligase RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039577">
        <property type="entry name" value="Rad18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004580">
        <property type="entry name" value="Rad18_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00599">
        <property type="entry name" value="rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14 17" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13 17" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15 17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="11 17" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12 17" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 16 17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="19">
        <location>
            <begin position="29"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="SAP" evidence="20">
        <location>
            <begin position="230"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="99"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="342"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="342"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU368093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EXK90454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="451" mass="50776" checksum="B3593894DE9ED55D" modified="2014-05-14" version="1">MADHDVPDSTDWLTTPLTALAAVESALRCQICKDFYKTPMITTCCHTFCSLCIRRALSNEGKCPLCRASEQELKLRSNWAMEEAVQAFINARPATLELARNANTKKTSSKRKTVEDHHESGDAPDGKRLRSSTRLRNTRSAPSYTVLAEEDETVGVSEDGEDFQPEPEDGLVACPVCESRMKEWQVFKHLEICTGPVQKPRGTPGSSSNTSFSQQRHQTKAPDRLPAMNYSMFKDQALRKKMSDLGISNQGPRILLERRHKEWMTIWNSNCDAARPRKRHELLHDLDVWERTQGGRAPTTGRSVQNAAIIKDKDFDGAAWAAKHDSSFKDLIANAKRSRLEAKKKAEEAANESKTDEETTPQENSDRMQDHSADWRAVSRPSAFPSRPAEGIPGRPSHSDSPSPEPSHSQSKGHRGSNRDSSRRPSDTRRDRFSQDQIHSNPWPENYDRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJ14</accession>
    <name>X0CJ14_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_13135</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJ14"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF11">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER (HXT8), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="1"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK82567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="521" mass="57008" checksum="D92059131ECB2CD1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJ71</accession>
    <name>X0CJ71_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">50S ribosomal protein L22e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_06997</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJ71"/>
    <dbReference type="eggNOG" id="KOG3434">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105624_0_0_1"/>
    <dbReference type="OrthoDB" id="10259820at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.210:FF:000001">
        <property type="entry name" value="60S ribosomal protein L22 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_eL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_eL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF31">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL22A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK90884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="124" mass="14200" checksum="5707D403181C3386" modified="2014-05-14" version="1">MAPQAKKSGKAQKQTKKYIIDASQPASDKIFDVSAFEKFLQDRIKVEGRTNNLGDNVVVKQSGEGKIEITAHNELSGRYLKYLTKKFLKKQQLRDWLRVVSTSRGVYELKFFNVVNDEADEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJJ3</accession>
    <name>X0CJJ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJJ3"/>
    <dbReference type="eggNOG" id="KOG1432">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000054">
        <property type="entry name" value="DCR2p Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="215"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="549" mass="60931" checksum="C2B360511E3A9F6C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJM6</accession>
    <name>X0CJM6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_13011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJM6"/>
    <dbReference type="eggNOG" id="ENOG502T43C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_537523_0_0_1"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033550">
        <property type="term" value="F:MAP kinase tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017017">
        <property type="term" value="F:MAP kinase tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008330">
        <property type="term" value="F:protein tyrosine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF519">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="507"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="150"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="539"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK82737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="587" mass="64891" checksum="B70A4300B4C94E4B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJS9</accession>
    <name>X0CJS9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJS9"/>
    <dbReference type="eggNOG" id="ENOG502SNCM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074385_0_0_1"/>
    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="247" mass="28214" checksum="8EA07CB94BBAC80C" modified="2014-05-14" version="1">MSDQSPCAILPESIDIPRITSTKQESTLNYYGPVDASLPTEASKFLARNTDAVEQELEHSIKAFLKTTQNDCSGLTEEKKACWLTIRITKPCTAFKIPRWHQDGPMFEYDQGREDVVRSKYALTLLGPSTLMLQPDEHVFTTQHEAEAQYYWWQNKTDGPEPSEDEMYEADDLLRESLGNAFKDTPRVQVGHGQVVRFSWGRDDSPVHSEPDLVSDRVFMTVLYGSESELRTMSKWREAPYGEHSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CK75</accession>
    <name>X0CK75_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial outer membrane protein porin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_06678</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic mitochondrial porin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CK75"/>
    <dbReference type="SMR" id="X0CK75"/>
    <dbReference type="eggNOG" id="KOG3126">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044399_0_0_1"/>
    <dbReference type="OrthoDB" id="7827681at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008308">
        <property type="term" value="F:voltage-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07306">
        <property type="entry name" value="Porin3_VDAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.10:FF:000004">
        <property type="entry name" value="Por1 mitochondrial outer membrane porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001925">
        <property type="entry name" value="Porin_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743:SF70">
        <property type="entry name" value="GH26960P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00185">
        <property type="entry name" value="EUKARYTPORIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-0626">Porin</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00054641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK91209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="283" mass="29816" checksum="9B9B7F821557B20E" modified="2014-05-14" version="1">MSVPAFSDIAKPANDLLNKDFYHLSATTFEFKDTAPNGVAFKVTGKSSHEKATSAAIEGKYTDKPTGLTLTQTWNTANALDTKIEVADSLAKGLKLEGLFNFLPATAAKGAKFNLHFKQPGFHGRAFFDLLKGPVANVDAVVGHEGFLAGASAGYDANKAALTAYSAAVGYAAPQYSAAITASDNLSVFAASYYHKVNSQVEAGAKATWNSKTGNAVGLEVASKYRIDPVSFTKVKINDRGIAALAYNVLLREGVTLGLGGSFDTQKLDQATHKLGASFTFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKA8</accession>
    <name>X0CKA8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OV-16 antigen</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658407">
        <property type="protein sequence ID" value="EXK82997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKA8"/>
    <dbReference type="eggNOG" id="KOG3346">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043994_3_1_1"/>
    <dbReference type="OrthoDB" id="2506647at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030162">
        <property type="term" value="P:regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046578">
        <property type="term" value="P:regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF85">
        <property type="entry name" value="INHIBITOR (TFS1), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="20852" checksum="7FC4A519B0F269CB" modified="2014-05-14" version="1">MSSALSSSLAEAKLVPGSAASLIPEGFKPTTNLKVSFDGKDVDLGNLFRASECKRAPSIQFDQEPDAPGDATYMLLLVDPDAPTPDDPKFAFWRHWVLPGLRPLSGGDAVAQVQPALTEYLGPGPKDDSKPHRYLLLLYRQPANLDLAKEDVGGEEFTQRRSFDTAKFVEKYGLRLVGANWFLGAGDGWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKL9</accession>
    <name>X0CKL9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03726</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKL9"/>
    <dbReference type="HOGENOM" id="CLU_031202_0_0_1"/>
    <dbReference type="OrthoDB" id="5419315at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF7">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK94985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="492" mass="55445" checksum="945E51858AA5BC95" modified="2014-05-14" version="1">MNESLRTPPSASTRRGGYTRQKRGCLTCRQRKKKCDQLYPICSHCLRLNLVCKREPPRSVLPSPGAATGGSEVTETRVVRTPSIDQQIKEVTQLCQPLGLSLEPGDANSKNLVGSRRVMLRYYTVTLAFLLTTNLENNCFLSVILPMAFECPALMYAVSAWASSHLALRDEKFRADSLRHRGHALAQLQKSMKQSELSTEMCLAVTMVLCSMESISEATDAWYPHLTGAAAALAWQSEGSLAVVDPKQAVQATFEGRWLLRNFAYHDIMMSVSMDCRPLVRGFYWASEDDTLADPYFGFASRILYLISETSILNADFAEAKLGSQTRGYSFAERSQKIESELQSWVCPSGHDDSPLALLGEAYRNAALIHLYRTLARYINSYSDILKAKLKACVESICKLSRQVSEGCLVECTLLFPLFMAGGEAHETSEIEIIREKLGEMIKWRKFRNVEACLDVLDEVWRRRMDGSRREDQDKVDWLDVVKQRGWKLSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKN6</accession>
    <name>X0CKN6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKN6"/>
    <dbReference type="HOGENOM" id="CLU_763018_0_0_1"/>
    <dbReference type="OrthoDB" id="2014058at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="421" mass="46640" checksum="8951389A8780D044" modified="2014-05-14" version="1">MRYEDWDVLLFEEGSSIPSREFKVTCHVVQHAESMGSALPTLTCFVPGLNAGVPFRLSIHSWKALKDLNGDHILNINNSVLETRLFIDGTLVAYASHLAAGIIANDGRSTSATGSIRFPLIINRQGHESLKFPFFQQELLYQRHWSPADNLGRIKLLINQSFSSASPSVLFTGKVNQTVVFSFQHAPQHILEGLQIAWPNPAMWNRQRQPSAPASTDSSHVSSRPPLFARRGLAGPEHINDAALGTMPFSGNPTFGCPNTPVNGPMSPWSYVLAPPGREGSPYLLASEVQPRRNHERAWPTSPIFTDATFRLDQTQNASQQMYPQPNSAPMSFVQPQLHSPAIQGSTEFGRGTPRNPARLIFAPKRNSPQESFNLDVIERATKRARTNTPESAKTLNHEQQNISPHFGSPYELINLAEDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CL43</accession>
    <name>X0CL43_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CL43"/>
    <dbReference type="eggNOG" id="KOG3184">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055156_0_2_1"/>
    <dbReference type="OrthoDB" id="28644at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01657">
        <property type="entry name" value="Ribosomal_L7_archeal_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000002">
        <property type="entry name" value="60S ribosomal protein L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039699">
        <property type="entry name" value="Ribosomal_uL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005998">
        <property type="entry name" value="Ribosomal_uL30_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035808">
        <property type="entry name" value="Ribosomal_uL30_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012988">
        <property type="entry name" value="Ribosomal_uL30_N_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01310">
        <property type="entry name" value="uL30_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08079">
        <property type="entry name" value="Ribosomal_L30_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30 N-terminal eukaryotes" evidence="6">
        <location>
            <begin position="13"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="5">
        <location>
            <begin position="89"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="24"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK92033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="248" mass="28500" checksum="E11B717B3DB6D74B" modified="2014-05-14" version="1">MGATVPTNDQILVPETLLKKRKSQEKARAERTDAIEKKKAANKEKRQVIFKRAEKYVQEYRDAEREKIRLHRVAKAEDSAFVPAEAKLIFVVRIKGINKMPPKPRKILQLLRLLQINNGVFVKVTKAITEMLKVVEPWIAYGYPNLKTVKELVYKRGYGKVNKQRVALTDNAIVEENLGKYGIVCVEDLIHEIYTVGPNFKQASNFLWPFKLSNPTGGFRPRKFKHFIEGGDLGNREEAINALIRQMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNM0</accession>
    <name>X0CNM0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502S6BV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001964_0_0_1"/>
    <dbReference type="OrthoDB" id="3946221at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="718"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="790"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1149"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1396"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="655"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="790"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="861"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="895"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="927"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="987"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1063"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1163"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1233"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1252"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1283"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1333"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1404"/>
            <end position="1419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1557" mass="171760" checksum="A603617CAE0AAEAD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNS7</accession>
    <name>X0CNS7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNS7"/>
    <dbReference type="HOGENOM" id="CLU_000288_138_18_1"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="21"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="2">
        <location>
            <begin position="224"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="611" mass="69434" checksum="0AC9017842BD3FAD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQU6</accession>
    <name>X0CQU6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_05378</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the exportin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQU6"/>
    <dbReference type="eggNOG" id="KOG2020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011906_0_0_1"/>
    <dbReference type="OrthoDB" id="27218at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000490">
        <property type="entry name" value="CRM1p Major karyopherin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041123">
        <property type="entry name" value="CRM1_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041235">
        <property type="entry name" value="Exp1_repeat_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014877">
        <property type="entry name" value="XPO1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040485">
        <property type="entry name" value="XPO1_repeat_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF2">
        <property type="entry name" value="EXPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08767">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18777">
        <property type="entry name" value="CRM1_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18784">
        <property type="entry name" value="CRM1_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18787">
        <property type="entry name" value="CRM1_repeat_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01102">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="26"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1053"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1053"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK93224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1079" mass="123695" checksum="CDD7F2C44E97052F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRX2</accession>
    <name>X0CRX2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_10617</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRX2"/>
    <dbReference type="HOGENOM" id="CLU_011099_3_2_1"/>
    <dbReference type="OrthoDB" id="3266505at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK85237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="667" mass="74047" checksum="5AA2A5093D61C65A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSN4</accession>
    <name>X0CSN4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSN4"/>
    <dbReference type="OrthoDB" id="4777826at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="154" mass="17021" checksum="665B4BE701E8CBA0" modified="2014-05-14" version="1">MPGKASDWDNADFLLDLVVGLYTGAQVNGGLTPPVKQSIEEYIKGRGYTTSFDAVRQHVQKLRKNRDTTAIQNSGGSETGTPRKRSSSTKTPAKRTPKRNATKSASIVDEDEDLEDEKMQLKMETDDMDEELMSPKGVKRTKSEPEDEVTVGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSQ2</accession>
    <name>X0CSQ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleoporin Nup54 alpha-helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_04448</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSQ2"/>
    <dbReference type="eggNOG" id="KOG3091">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023804_0_0_1"/>
    <dbReference type="OrthoDB" id="6162375at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044613">
        <property type="term" value="C:nuclear pore central transport channel"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006607">
        <property type="term" value="P:NLS-bearing protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036228">
        <property type="term" value="P:protein localization to nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.3600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.490">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024864">
        <property type="entry name" value="Nup54/Nup57/Nup44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025712">
        <property type="entry name" value="Nup54_alpha-helical_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13000">
        <property type="entry name" value="NUCLEOPORIN P54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13000:SF0">
        <property type="entry name" value="NUCLEOPORIN P54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13874">
        <property type="entry name" value="Nup54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18570">
        <property type="entry name" value="Nup54_57_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup54 alpha-helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="14"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK94343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="327" mass="37028" checksum="F6205BE57F131808" modified="2014-05-14" version="1">MSLFGQAKPSLFGQSQPAQTTAPTQSTGFGLGQPQQQQQGNTLGASIQQPQPQQMPALSQSQAQLSNSLWQPGKETPHQKPILEQMKLVTEKWDPANPNCVFKYYFYNKVDESHVPYYKPQPHEDPREWEEALQNKPAPGFMPVLCSGYAGVADRLKTQQRAVADFNTRLHQINGSLDAILQRHELETEVRAVAARRRQTTISERCLALAARIQVLRNRGYALSGDEDDLSSRLQTLEREVQDPAVGAREEELWSRLIVLRGYADQLSKELDKPTGSEGESIDPEREAKAKRVLEDYEKQIQHIKKELEALSTDYAEWEKTRNPHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT52</accession>
    <name>X0CT52_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Translation initiation factor IF-2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_02760</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT52"/>
    <dbReference type="eggNOG" id="KOG1145">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006301_8_3_1"/>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03692">
        <property type="entry name" value="mtIF2_IVc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000007">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000008">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10050:FF:000001">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000019">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF20">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 13" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="12">
        <location>
            <begin position="508"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="127"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="343"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="485"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="780"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="373"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="780"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK97630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1032" mass="113263" checksum="C873E6A826AA8B1C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU71</accession>
    <name>X0CU71_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_01048</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU71"/>
    <dbReference type="HOGENOM" id="CLU_880118_0_0_1"/>
    <dbReference type="OrthoDB" id="10342330at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003284">
        <property type="entry name" value="Sal_SpvB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03534">
        <property type="entry name" value="SpvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK98005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="332" mass="36091" checksum="F3163CDA0C6947B0" modified="2014-05-14" version="1">MSSYSSAIDRQQGKADTDNNGVARYVLEIETPAGIKSGNEPDLSLQYSQGTPNGILGLSWVLGGVSSIYLGAPKVVYGKVNPPPPDYDTSKPKLIMDGLDLLNPDREYNGPQTVYTTEINSTGLQVKSLGEDGGFLVTDNMGRQIEYGTTLDSRIVTQPEGKAREWRIMKQTDCHGNTIQYNYIPSPQTENTRDVNTSYLGSIKYCSNDVTDFPATRFVQFHYADRKDLVTHSIAGAIITRANLLSSISIGINIGGEITVNRTYSLTYGQSATTNDSYLSQVAESSEKDGQAVSLLPTSFSYTAQDTVPGDLFKTVPADPFQAESNVVTCFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUM7</accession>
    <name>X0CUM7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09879</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUM7"/>
    <dbReference type="eggNOG" id="KOG2071">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015606_0_0_1"/>
    <dbReference type="OrthoDB" id="343582at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005849">
        <property type="term" value="C:mRNA cleavage factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16982">
        <property type="entry name" value="CID_Pcf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000016">
        <property type="entry name" value="mRNA cleavage factor complex component Pcf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045154">
        <property type="entry name" value="PCF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054127">
        <property type="entry name" value="Pcf11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047415">
        <property type="entry name" value="Pcf11_CID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021605">
        <property type="entry name" value="Pcf11_Clp1-ID"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921:SF3">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21936">
        <property type="entry name" value="Pcf11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11526">
        <property type="entry name" value="Pfc11_Clp1_ID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="4"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="602" mass="65902" checksum="03F2F4420969B20A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-09-13" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV65</accession>
    <name>X0CV65_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV65"/>
    <dbReference type="HOGENOM" id="CLU_839590_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="39967" checksum="C78D388372825B5A" modified="2014-05-14" version="1">MAEEKKSYKWISKAIESLDAEKDYAEIFRLSMSYGGNDFMNTLIYCLVFPNFIVTEWGARVIWRRDGGKVLRKAANRVEQTENKNAAWWWYGPHDPRTKQSVESINNLHAYWAKHYEGDFSHNEDYIYTLAFTAIVMHRLRLMLGLPDVSEKIKTASYLVMRDMVPLFRAEGGKPIHSFPSDWYGLLKFCEDFENQPHPGSEQGNLCANAMYDFFAFRYFPKPLRWLGRAIPIALSLPTTLKAHRIKPVNPVLRAVIVWVFGWLFWLQDNVLPDPQVAFLPQLQSLSPEEQSRRTTEIRKLDREYPAYFAKQHSNLGQWGGCPFHEALGMINDGGVPDKDYKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYF2</accession>
    <name>X0CYF2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_00038</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYF2"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000090">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF37">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="12"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK99555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="506" mass="55662" checksum="B6584621953E7E36" modified="2014-05-14" version="1">MALPPKWYQFLVSVFASLGSLLYGYDLGVIAEVIASGNFKSKFGDDPNATGAVVSVFTGGAFFGAMFAGYAGDRLGRKWTIMIGALIFILGGSLQTAADHINYLYAGRCLAGLGVGFLVMIVPVYQGELCHPDIRGRVTALQQFMLGIGALVATAIGYGTYTGIGDDNSGQWRIPLGIQNLPAVILAALILFFPESPRWLIDHGRADEGLQTLAKLHAHGDINDTWVRAEFDQIQERLAMEHEASAKSYSELFTDKSCFRRLWLAISVQVAAQMTGVSAIQYYSVEIYAKIGIKGDETLRYQMISSVIALVAQFICMLVIDRTGRRWPLIGGNILNCITFIIATVLLASFPPGSENTGGGAAGWGFIVVTWIYNFSFSATCGPLSWIIPAEIFDMKTRAKGVSLATMMSFAFNTMIGQTTSVALDDKHGIGWRWYILFIVCNFTNALYFWAILPETANRPLEEMRYLFTEAPLFVPLMDQAKFAAGQDLERRVEKAEQTQELEHQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZX6</accession>
    <name>X0CZX6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Deoxyribodipyrimidine photo-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_03460</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="6">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZX6"/>
    <dbReference type="eggNOG" id="KOG0133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010348_2_1_1"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.579.10:FF:000003">
        <property type="entry name" value="Deoxyribodipyrimidine photo-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF18">
        <property type="entry name" value="SI:CH1073-390K14.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="9">
        <location>
            <begin position="136"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="36"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="388"/>
            <end position="392"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="431"/>
            <end position="438"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="529"/>
            <end position="531"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="463"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="516"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK96419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="630" mass="71998" checksum="69BF7B0917A626DD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZZ7</accession>
    <name>X0CZZ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rhamnogalacturonan endolyase</fullName>
            <ecNumber evidence="4">4.2.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_08465</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1-&gt;4)-alpha-D-galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non-reducing end.</text>
            <dbReference type="EC" id="4.2.2.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide lyase 4 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.23" evidence="4"/>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZZ7"/>
    <dbReference type="eggNOG" id="ENOG502QTKY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037882_1_0_1"/>
    <dbReference type="OrthoDB" id="114708at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102210">
        <property type="term" value="F:rhamnogalacturonan endolyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10320">
        <property type="entry name" value="RGL4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1120">
        <property type="entry name" value="Carboxypeptidase-like, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029413">
        <property type="entry name" value="RG-lyase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016590">
        <property type="entry name" value="Rhamnogalacturonase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015364">
        <property type="entry name" value="RhgB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36574">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36574:SF1">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14686">
        <property type="entry name" value="fn3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09284">
        <property type="entry name" value="RhgB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937553" description="rhamnogalacturonan endolyase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase B N-terminal" evidence="12">
        <location>
            <begin position="20"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase" evidence="13">
        <location>
            <begin position="285"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK88022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="406" mass="43925" checksum="422E12251B4E79F2" modified="2014-05-14" version="1">MVSFKYLGALASAAPALAAFGVTTSGNNLVVDSGNSNGFSVTVSKSDCSINSIKYRGAEYQYKSQTSHIASGLGSSTVQSTVLNNKYIKITCTTKSGDFDLTHYYVVQNGQSVVYMATDTKSQPAIGELRYITRLDRSQLPNEIPFGEASNTSGGSAVEGSDVFNVNGETRSKFYSSQRFIDNDVWCFQSSAKDVHACMVTHASRSYEKSSGGPFFRDINSNNNGDFSALTFYMNSGHAKTEEFRQGFHGPYALSFSRSGVPKAQDIDMSFFKDLSIPNYTADSSRGRVSGTATGVQSGFQGVVHWFNKDFQYWAYTSSNGAFTSPFMVPGTYTQVLYQGELKVASKSVSVSAGSTASSSIAANSDITTGEHTSVFRIGDWDGQPKGFRNAANQLRMHPSDKRMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0E2</accession>
    <name>X0D0E2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00477</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0E2"/>
    <dbReference type="eggNOG" id="KOG2730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029658_0_1_1"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000270">
        <property type="entry name" value="RNA methylase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL00216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="266" mass="30146" checksum="B0354EA017A8329F" modified="2014-05-14" version="1">MSSSGVEMSLDDSEYSMKPAEELPLTDDCHHYQGKHEVPWDIQKYFAQRYSIFSLYDYGVYMTDDAWFGVTPEPVANQVAHDMYGTDQKKHILIDVFGGAGGNSIAFALSERWSRVISIERDPSTLACAQNNAKVYGIAPGLITWVLGDSFEYLDKLFNHTEELHPNLRVSLDETVLFASPPWGGPGYRTDEVFNLYNMQPYNLDDLHTAYNRLDHALFLPRTSDIRQIARLAPPDRKVEVVQYCMEGASKALVAYLPGKYSKARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0T7</accession>
    <name>X0D0T7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mitochondrial import protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0T7"/>
    <dbReference type="eggNOG" id="ENOG502SBHA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127808_0_0_1"/>
    <dbReference type="OrthoDB" id="5529571at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070096">
        <property type="term" value="P:mitochondrial outer membrane translocase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013262">
        <property type="entry name" value="OMP_MIM1/TOM13_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08219">
        <property type="entry name" value="TOM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="13416" checksum="D2AADF3FACB07FE0" modified="2014-05-14" version="1">MSDEHNHLAESGVTLHSDSELYSAGDDLSSPPSSNSPVILYKPPTVWSLIRGAAINLLLPFVNGMMLGFGELFAHEAAFRLGWGGTKVFPLSRRRVHPIGPGIELREKSYAPRPSLDDFASLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0D292</accession>
    <name>X0D292_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08077</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D292"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_1"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19079">
        <property type="entry name" value="AKR_EcYajO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000004">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF15">
        <property type="entry name" value="ARYL-ALCOHOL DEHYDROGENASE AAD16-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="338" mass="38207" checksum="15363EFF3B566018" modified="2014-05-14" version="1">MSSRVGKSGLKVSQIILGCMSFGDKNWQPWLLDKDEALPILKYAFDKGINTWDVADTYSNGESERILGAAIKHYNIPRSKLVIMSKCFQFVDEEKGPIDPATLTSNDGPRVNRVGLSRKHILDAVDQSVERLGTYIDVLQIHRMDRDVPPEEIMKALNDVIESGKVRYIGASSMAAWEFQMLQNVAEKNGWHKFISMQGLYNLLYREEEREMNPYCNYTGVGLFPWSPLAAGVLAHSWTDRTDAREQKDPFLKLLFRGEDQNADRAIVDRVEQLAQKKGVAMAQIAQSWLIAKGCMPICGLESKERIDQAVGALQVTLSDEEIAYLEELYVPKVPFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2M0</accession>
    <name>X0D2M0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_00724</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2M0"/>
    <dbReference type="eggNOG" id="KOG3072">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017661_2_0_1"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF169">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXL00652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="472" mass="51279" checksum="60F0D1F60C74A83A" modified="2014-05-14" version="1">MADHFQLLRSTPDSSLFSFPPANAPAPIAPVEVPTSILRPFNIPEHIFTGALDAKVPLTIAILYAVTVKSLNIYNKSNGKKPWAISKTRPFFAFVVLHNVFLCVYSAWTFWGMLGGMKRSIVNPTGPQGLAGMADSFCRLHGSSDLGNSVYYNETTSSFVSSAENAAIVDGLPSGTVGGRLWNEGLAYYGWIFYLSKFYEVLDTFIILAKGKLSSTLQTYHHAGAMLCMWAGMRYMSAPIWQFVLINSFIHSLMYFYYTLTAFNIRVPTPVKRTLTSMQITQFLVGASNTVAHSFISYKVPVTIIQKLSAPVGATTAAPDASQETVVDGAVESLKKFIWGAGEGADPIASQAVSAEAFAAETQYITQPCIMTTGETFAIWLNVLYLAPLTYLFVSFFIASYVKRSNAASKTSHKGAHDVNANIALAEKAGWDAAKGIEKEIYDGANMANGSSDEASRASTPKKANGKSRRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0D324</accession>
    <name>X0D324_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D324"/>
    <dbReference type="OrthoDB" id="978at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF13">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938174" evidence="1">
        <location>
            <begin position="22"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="478" mass="54384" checksum="0156871CE813B24B" modified="2014-05-14" version="1">MKPHLVASMALTLLFAPLCTSADENIKVDALKQNNPDLASIPNLVCLLLFLLLIAYKLRKRMLTATTTFPQLTRRSQSGSVVTSLEKFSCNPDTPRHVEAKKKLDKSMAIGWGNWNAQHPRHRLLDALYGYRRYHERQKAEVDRFEGLYKHVSRAQKSLLEHQVNYSKKFTRIDALLKKNQELCDVIVQNAMNFYGINEEELQRHISAAQSSGRLADKISVSQALKHYVRDWTEEGESERKETFACLVATLQGLFPVRDDENPVKVLVPGSGLGRLGHDIARLGGFEVTVNEWSMYMNIAYRFIEANRAQNTHSFHPFIDGWSHHATESDMIRELTFPDTSLNSTSVVLTEGDFTTVFNDKTGYYDIIVTYFFIDTARNLMSYLDTIKKVLKPGGHWVNLGPLLYGTGPFVQLTLEEIVQVTEAMGFEYLDTEESCGPLTFEGRTIRSMEAVYGFNNKALTKSAYNAQFWVARRSMKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3Z3</accession>
    <name>X0D3Z3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">UDP-glucose:glycoprotein glucosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_02881</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1879">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002668_1_0_1"/>
    <dbReference type="OrthoDB" id="27683at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003980">
        <property type="term" value="F:UDP-glucose:glycoprotein glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06432">
        <property type="entry name" value="GT8_HUGT1_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000065">
        <property type="entry name" value="UDP-glucose:glycoprotein glucosyltransferase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040497">
        <property type="entry name" value="Glyco_transf_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009448">
        <property type="entry name" value="UDP-g_GGtrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040693">
        <property type="entry name" value="UGGT_TRXL_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040694">
        <property type="entry name" value="UGGT_TRXL_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040692">
        <property type="entry name" value="UGGT_TRXL_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040525">
        <property type="entry name" value="UGGT_TRXL_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226">
        <property type="entry name" value="UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226:SF0">
        <property type="entry name" value="UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18404">
        <property type="entry name" value="Glyco_transf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18400">
        <property type="entry name" value="Thioredoxin_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18401">
        <property type="entry name" value="Thioredoxin_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18402">
        <property type="entry name" value="Thioredoxin_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18403">
        <property type="entry name" value="Thioredoxin_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06427">
        <property type="entry name" value="UDP-g_GGTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936807" description="UDP-glucose:glycoprotein glucosyltransferase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="11">
        <location>
            <begin position="35"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="12">
        <location>
            <begin position="265"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="13">
        <location>
            <begin position="402"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="UDP-glucose:glycoprotein glucosyltransferase thioredoxin-like" evidence="14">
        <location>
            <begin position="656"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="domain" description="Glucosyltransferase 24 catalytic" evidence="15">
        <location>
            <begin position="1167"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1437"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1440"/>
            <end position="1464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK97844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1464" mass="162562" checksum="FB69C01F3218CCE5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0D412</accession>
    <name>X0D412_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00983</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LIMR family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D412"/>
    <dbReference type="eggNOG" id="KOG2296">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016542_1_0_1"/>
    <dbReference type="OrthoDB" id="203099at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051584">
        <property type="entry name" value="GPCR-associated_LMBR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355:SF0">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="595"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="664"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="595"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL01142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="700" mass="78524" checksum="22D0B0D2CDF2E632" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0D441</accession>
    <name>X0D441_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D441"/>
    <dbReference type="HOGENOM" id="CLU_3406382_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="30" mass="3404" checksum="5CEE6FFB91921551" modified="2014-05-14" version="1">MSFLAFGEDSPRRRLCLLALFMRAAMMIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4Q5</accession>
    <name>X0D4Q5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nascent polypeptide-associated complex subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Alpha-NAC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_01429</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAC-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4Q5"/>
    <dbReference type="eggNOG" id="KOG2239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057806_2_0_1"/>
    <dbReference type="OrthoDB" id="3169036at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005854">
        <property type="term" value="C:nascent polypeptide-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22054">
        <property type="entry name" value="NAC_NACA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14358">
        <property type="entry name" value="UBA_NAC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000002">
        <property type="entry name" value="Nascent polypeptide-associated complex (NAC), alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000006">
        <property type="entry name" value="Putative nascent polypeptide-associated complex subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016641">
        <property type="entry name" value="EGD2/NACA0like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21713">
        <property type="entry name" value="NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015901">
        <property type="entry name" value="NAC_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NAC-A/B" evidence="8">
        <location>
            <begin position="49"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="121"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK98558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="209" mass="23079" checksum="7D934224D8E4EBF7" modified="2014-05-14" version="1">MSNPRVEELPDEEPKKTTVQEHEDDSSDDSEVEEVGEGQLPAGSTVIHNRNEKKARKALEKLHLTRIPGITRVTLRRPKNILFVINNPEVYKSPNSNTYIVFGEAKIEDVNAAAQQAAAAQLASANAEDHSGHNHGEPSKAAETAEEKKDKEDEEEEEEDDDEEVDASGLEDKDIELVMTQANVSRNKAVKALKENDNDIVNSIMALSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0D615</accession>
    <name>X0D615_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Vacuolar protein sorting-associated protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_01451</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Endosome membrane</location>
            <topology evidence="2 12">Peripheral membrane protein</topology>
            <orientation evidence="2 12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the VPS27 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D615"/>
    <dbReference type="eggNOG" id="KOG1818">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011862_1_0_1"/>
    <dbReference type="OrthoDB" id="957735at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15735">
        <property type="entry name" value="FYVE_spVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21385">
        <property type="entry name" value="GAT_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16979">
        <property type="entry name" value="VHS_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1940:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000031">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000161">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017073">
        <property type="entry name" value="HGS/VPS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049425">
        <property type="entry name" value="Vps27_GAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21356">
        <property type="entry name" value="Vps27_GAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036956">
        <property type="entry name" value="Hrs_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0967">Endosome</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VHS" evidence="16">
        <location>
            <begin position="26"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="15">
        <location>
            <begin position="168"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="230"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="284"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="452"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="494"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="504"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="515"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="550"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="610"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="637"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="669"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="689"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="717"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="733"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK98584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="742" mass="81598" checksum="AA65676A465744ED" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0DB98</accession>
    <name>X0DB98_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DB98"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF5">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXL00824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="465" mass="51351" checksum="9BA1CC648C80349D" modified="2014-05-14" version="1">MGETTKIQKGKVSAKRNSEARREQNRLASRNYREKRKQKLALLNELLEPSNLSSITGNGHIDDVPGPSGSTDTGAPPLQSQTLSSAPLTNHLIPLDLNRSDGTGTFLVPQTWEDFTQESVPTVISNQLIPEFLPVLNKGNPPSLGSHDQWEDVMPGLIQQSSTFTGQPPADYMGYRAIEEVFEDSPDSDHSGSQGASSNDDGSLKDVLYGVESLSIEQKRSLLRHLQQDIRGPKSPSSSQNILHQTPGQLQAIQFAKALYKTANARPSLFPAQYTMEPGIFGAIFANCYALGMGGVDEILHDDGCSVFSVTPDEGHHPSKLSFVKSRFLDVSSDLQPIEKQLTFGHHPYIDVIPFKIFRENLITVLDQDPNAIDEGALCHDILSGGFTCWGAGRNSHGMGAGVPWDSRSWEPSIWFLMKYRALAGEWDGELWKSARWWHSARGERIQISQEIDIGSNMFQGTPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBD7</accession>
    <name>X0DBD7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBD7"/>
    <dbReference type="eggNOG" id="ENOG502SXSQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033647_0_0_1"/>
    <dbReference type="OrthoDB" id="5422579at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="60602" checksum="597F088C20C33779" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCZ7</accession>
    <name>X0DCZ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Succinate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_00889</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 8">
            <text>succinate semialdehyde + NAD(+) + H2O = succinate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13217"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 8">
            <text>succinate semialdehyde + NADP(+) + H2O = succinate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13213"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.16" evidence="8"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCZ7"/>
    <dbReference type="eggNOG" id="KOG2451">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="UniPathway" id="UPA00733"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036243">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07103">
        <property type="entry name" value="ALDH_F5_SSADH_GabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000005">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010102">
        <property type="entry name" value="Succ_semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01780">
        <property type="entry name" value="SSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF5">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00050387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00052698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXL00995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="490" mass="52595" checksum="452D6CBC97F1DB4A" modified="2014-05-14" version="1">MTAPKLTDPTLIKNACYVNGEWVAAKSGKDFAVENPSTLEKIGNCPEFDASDTEAAIAAADAAYKTYRKTPARQRARYLRRWYDLMMENSEDIARLITLENGKPLADGRTEANYAAAFFEWFSEEAPRIYGETIEATNPSCRLSTIKQPVGVCGLIAPWNFPAAMITRKAGPALAAGCTVVIKAPAEAPLTALALAELAHRAGIPAGVVNVITALDNTAEVGKVLTTHPKVKKVSFTGSTGVGRLLMNQSSSTIKKLSFELGGNAPFIVFEDADLDKAVKGVIACKFRNSGQTCVCANRILVHRSIYDKFVQMVLDVVKTFVVGDGFGEKTTHGPLIHGRAVAKAAEHVEDALSKGAKLIHGGERLPHLGPNYFDLTMLTGMKPGMKICSEETFGPVAAFFAFDNEDEAIELANDSDVGLGGYFFSNNVNRCYRVAEALEVGMVGVNCGVLSDPAAPFGGIKQSGFGREGSKYGIDEFTITKMVMTNIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0DLG2</accession>
    <name>X0DLG2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TEL2-interacting protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_03831</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DLG2"/>
    <dbReference type="eggNOG" id="KOG4524">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005544_0_0_1"/>
    <dbReference type="OrthoDB" id="49511at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052587">
        <property type="entry name" value="TELO2-interacting_protein_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057567">
        <property type="entry name" value="TPR_TTI1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057566">
        <property type="entry name" value="TPR_TTI1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016441">
        <property type="entry name" value="Tti1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049362">
        <property type="entry name" value="TTI1_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18460">
        <property type="entry name" value="TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18460:SF3">
        <property type="entry name" value="TELO2-INTERACTING PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24181">
        <property type="entry name" value="TPR_TTI1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24173">
        <property type="entry name" value="TPR_TTI1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21547">
        <property type="entry name" value="TTI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005250">
        <property type="entry name" value="UCP005250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TTI1 N-terminal TPR" evidence="2">
        <location>
            <begin position="14"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="TTI1 C-terminal TPR" evidence="3">
        <location>
            <begin position="735"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="737"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK95177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1062" mass="117594" checksum="B62956085ED3D967" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0DM01</accession>
    <name>X0DM01_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_03974</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DM01"/>
    <dbReference type="eggNOG" id="ENOG502SU65">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_279786_0_0_1"/>
    <dbReference type="OrthoDB" id="342281at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034993">
        <property type="term" value="C:meiotic nuclear membrane microtubule tethering complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045119">
        <property type="entry name" value="SUN1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012919">
        <property type="entry name" value="SUN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911:SF8">
        <property type="entry name" value="KLAROID PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911">
        <property type="entry name" value="SAD1/UNC-84-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51469">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="SUN" evidence="8">
        <location>
            <begin position="827"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="356"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="181"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK95397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1031" mass="115703" checksum="BC8DC097DE1651E2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0DM31</accession>
    <name>X0DM31_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">L-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="16">1.1.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">FOQG_04004</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(S)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:19909"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:19910"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the C-terminal section; belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">In the N-terminal section; belongs to the cytochrome b5 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.3" evidence="16"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DM31"/>
    <dbReference type="eggNOG" id="KOG0538">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_1_0_1"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004460">
        <property type="term" value="F:L-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02922">
        <property type="entry name" value="FCB2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000062">
        <property type="entry name" value="Cytochrome b2, mitochondrial, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037458">
        <property type="entry name" value="L-MDH/L-LDH_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF104">
        <property type="entry name" value="CYTOCHROME B2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 19" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 19" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="21">
        <location>
            <begin position="27"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <begin position="106"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00052399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00061137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00061589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00066458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00068515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EXK95432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="410" mass="44473" checksum="AF3AC7C7EB5F8EFA" modified="2014-05-14" version="1">MSDLAAMESESPNIPSPREIQLPSSVPSLDQILSAHDFSLAAQKALSPKAWAFYSSAATDLVTVSKNKELIRRVMLRPRILRNVAEVSIKRNILGLESKAPFIMCPAAMATLAHPDGELGWSRAAASEGIFEIISSNASYSLPNIIGAAPSGHPFFLQLYVNSHRPKTIELLRRARSLGIKAIFVTVDAPVPGKREADERAPQAVVIKSAMSGSESSKDGKGSGLGRLMGQYIDKSLSWEDLEWIRRESSVPIVLKGVQTVEDVKLAVEYGVEGVMLSNHGGRSLDGAQASILILLEVRKRFPEAFQHLEIFIDGGFERGSDILKAIALGATAVGIARPFLYSLVYGQKGVEHLSQILKDELETSMRLAGITSLDQATPELVNTLDVDHLVTSGRIEPSSVSRRVRSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0DRC9</accession>
    <name>X0DRC9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative phospholipase</fullName>
            <ecNumber evidence="4">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_02243</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30909"/>
            <dbReference type="ChEBI" id="CHEBI:36707"/>
            <dbReference type="EC" id="3.1.1.47"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the serine esterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.47" evidence="4"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DRC9"/>
    <dbReference type="eggNOG" id="KOG3847">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024458_0_0_1"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016715">
        <property type="entry name" value="PAF_acetylhydro_eukaryote"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF7">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018169">
        <property type="entry name" value="PAF_acetylhydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="517"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="517"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR018169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR018169-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK96832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="559" mass="62011" checksum="F055FF6814178D50" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B0W3</accession>
    <name>X0B0W3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979865">
        <property type="protein sequence ID" value="EXK75730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B0W3"/>
    <dbReference type="HOGENOM" id="CLU_2589861_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="80" mass="8362" checksum="73E376B13F62125A" modified="2014-05-14" version="1">MLRASSYMNGPSPFVLVNQSLFGTDRKGISAALTPAGDDDVAPNFSVSPNSHAEYNLGSGFTTCAPSSHSYVVLSFTTAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0B185</accession>
    <name>X0B185_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_19361</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979744">
        <property type="protein sequence ID" value="EXK75875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B185"/>
    <dbReference type="HOGENOM" id="CLU_176441_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002112">
        <property type="entry name" value="Leuzip_Jun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00043">
        <property type="entry name" value="LEUZIPPRJUN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="6"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK75875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="95" mass="11283" checksum="E063DFEB926F222C" modified="2014-05-14" version="1">MTNRKHAKHKQVQERNRIAAEKCRMRKKEELARLQSDEQAIEQRHRMLSSCVDDLKEEILHLKTQLLQHTSCNCTLIHHHIEKEAQCYTDALGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1H0</accession>
    <name>X0B1H0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979684">
        <property type="protein sequence ID" value="EXK75965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1H0"/>
    <dbReference type="HOGENOM" id="CLU_3399507_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="31" mass="3284" checksum="875517B951CC5DDC" modified="2014-05-14" version="1">MLGGRPEPSNVPCSPQLGIYFPTTPTPSNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0B374</accession>
    <name>X0B374_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_19069</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979577">
        <property type="protein sequence ID" value="EXK76171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B374"/>
    <dbReference type="HOGENOM" id="CLU_079951_1_1_1"/>
    <dbReference type="OrthoDB" id="4074965at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39608">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G08640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39608:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G08640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="7">
        <location>
            <begin position="13"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK76171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="208" mass="23388" checksum="E8B52FEC6248B425" modified="2014-05-14" version="1">MAEKETGVAHKVISVILRLAELASAIIVLGILSRFCYLAGIAQVHIDGRIIYAIVVACLGIIYSVLFCPPFKNMFLGFPFDFVLFVMWLVAYCLLQTRTGSHTCSASWYYNYWGYYWGRFWRVGPVGTVHIGDAGCASWRTALAFSFIAWFLHLLSGILGAYVFATYIKLDESKKDIKQHAEKLTKPDSRAKGYHQGIEPQSDNVNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5D3</accession>
    <name>X0B5D3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979395">
        <property type="protein sequence ID" value="EXK77325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5D3"/>
    <dbReference type="HOGENOM" id="CLU_2812473_0_0_1"/>
    <dbReference type="OrthoDB" id="5109137at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="67" mass="7885" checksum="849CFFFDED996812" modified="2014-05-14" version="1">MWFRPMPLILIKDEDLIYHGKTLSVRYEEGRLRAIHATMCISEYRSRLRRPASPENPDNSSSPQVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0B640</accession>
    <name>X0B640_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979404">
        <property type="protein sequence ID" value="EXK77216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B640"/>
    <dbReference type="HOGENOM" id="CLU_003093_0_0_1"/>
    <dbReference type="OrthoDB" id="5222260at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022698">
        <property type="entry name" value="OrsD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12013">
        <property type="entry name" value="OrsD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1051"/>
            <end position="1062"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1242" mass="143265" checksum="B1C947BF4749B241" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6P5</accession>
    <name>X0B6P5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658607">
        <property type="protein sequence ID" value="EXK77441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6P5"/>
    <dbReference type="HOGENOM" id="CLU_000680_23_4_1"/>
    <dbReference type="OrthoDB" id="5243754at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="169" mass="19105" checksum="D27DA89D410685E4" modified="2014-05-14" version="1">MVLRCMPDGLQHRDIIVATRNRSALQAIAKPRQQSGQGAFREIYRHARRLEKGSTTIKMRWVSSTNESFTQGVKAKTEARKATESGCKATKLPHQARSTRLRVLLAQRRRLMVLPEGVGGYSKRLDKALPGKHTRILYDALKRRESDILVQLRTGMACVSRYLHRIGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0B869</accession>
    <name>X0B869_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PD-(D/E)XK nuclease-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658555">
        <property type="protein sequence ID" value="EXK77976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B869"/>
    <dbReference type="HOGENOM" id="CLU_027219_2_1_1"/>
    <dbReference type="OrthoDB" id="4161186at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046797">
        <property type="entry name" value="PDDEXK_12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20516">
        <property type="entry name" value="PDDEXK_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PD-(D/E)XK nuclease-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="248" mass="27459" checksum="D61702AFCCF69B18" modified="2014-05-14" version="1">MVDRIVVESARCSKYFDEPGWNNLVHSPILNAVFNQRFWPGDEHEMVEYSPVITAPVTAVHHMFPHSSAKVDYVVHIQPPPETQDAVETLYESTSEKSVNHTAFPPLRRSPISLTIETKRYGGNHAKANAQVCSWQAAQWTCLASQAGEGIKHLPFLPGMVVNGPSWTFVATTRNGDKTTIWTDAAMGSTTSSLGVLKVMGALNGLRQWTIKVYWPWYKKHVLKIGQVDTRPAQVEGDAEMDSGTAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0B949</accession>
    <name>X0B949_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein RTA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_17039</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658530">
        <property type="protein sequence ID" value="EXK78281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B949"/>
    <dbReference type="HOGENOM" id="CLU_033465_3_1_1"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF35">
        <property type="entry name" value="RTA1 DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK78281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="32948" checksum="320C79A901E52C28" modified="2014-05-14" version="1">MTSNSTSDTDVDEFKLYLYKPSLVAAIILTVLFGVVSARHSQLLFKTRTWSFIPFSIGCLVETVGYGARAYSATQTPDWELMPYILQSVFILLGPAFFAASIYMVLGRLICFLEGQHLSMIKVNRLTKIFLLGDILSFFGQGGGGGLLASASDKGSQDLGNNIIIVGLAIQVIFFGGFMVITAIFHVRILRQPTKRSQTTGAPWQVFMAVLYFTSALIMVRSVFRMIEYAQGHNGALISKEVYVYTLDALLMIVVAATFTVRHPSAIFTYQAMSDLFGHDSGNLDNMPMVAPRPYAVMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAM3</accession>
    <name>X0BAM3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658500">
        <property type="protein sequence ID" value="EXK78816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAM3"/>
    <dbReference type="HOGENOM" id="CLU_038374_6_0_1"/>
    <dbReference type="OrthoDB" id="5392716at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="2">
        <location>
            <begin position="59"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="424" mass="49209" checksum="D66D8DE5F67B1567" modified="2014-05-14" version="1">MTRRSNAISGYGKSLLQPYLRQKKQLWVPRDPLFAMYKIMFPNEVELRKRMFRRKKGQFLVPGPNYQWCIDGHDKLKAYGFEIYAAIDAYSRNIIWFYVGHTATTALSVLKQYLAACDAYGFRPWYLQADRGSETPLIAAAHWNFVLATDGRVEWHGQVFQQGKRLKDSYKAAPSTKNVKIESWWERMLHVSSRQWVDYFGELARDGDFDSDMLEDQIAIYAVFEDVLRQELFDFVEAWNLHRIRLQKNRPHVIHGQPWMNYHYPDPDKACNWGIPIDRSVLGEMERPLADIDISTCLEPETKNWCRQVLLEMGYDQVVLGTRQEPDKLRPFKRFYLGLRDRIIQHIESGQQPVLAYRKAPTGGVAEYQALLERANQARGEELGDGEPAEQPLVELGFEDEEGNDIEEISDDGEDSDSSNGEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAR9</accession>
    <name>X0BAR9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16126</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979350">
        <property type="protein sequence ID" value="EXK79235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAR9"/>
    <dbReference type="eggNOG" id="ENOG502SIRW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022730_0_0_1"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF284">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936341" description="FAD dependent oxidoreductase domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="79"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="497" mass="54430" checksum="B90D9281250A1F60" modified="2014-05-14" version="1">MRSSLSQVATASILLASGVNSLAVAHPHSLRSDTPDESPALKIPGLPLPNATKSYWQDPPHRIANLRTTKDLPTEKTFDYVIIGSGISGAATAHKLLDRDSSLSILMIEARTAASGATGRNGGHCKPGDYNGVKAWVEAYGEDDALRIANMEQDCVDDVRDFVRSHNVSSDFTDVETASLYWTDDSFKTAVESIEFQHELEKRRPNDVPKNKRTIWKGQDARDYWGWPEIVGAVTFKAHTQNPYHTVCGMLEYSLEKGLNLQTNTMALSLNQLSKKTKAGARWEVKTNRGTVKSKQVVLATNGFTPALHPGIASTNFTMPVRNQVSAVTPSANTTDNKVFRRSNSVPDLHSGNVYIAAQPPGAKNAGSVVIGGSTQMSPTRERYITDDTAINDQIAYVLHGAARTVYGYENWGGSTKVIQDWTGIVCETPDGFPLVGEVPAEDGLWAIVCMNGHGMAWAYRSAEALVDMMTEGKTPKWFPEQFKAQRAWEVQSNEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBD6</accession>
    <name>X0BBD6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979813">
        <property type="protein sequence ID" value="EXK75789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBD6"/>
    <dbReference type="HOGENOM" id="CLU_3359773_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="36" mass="4079" checksum="BBB26D02DD93E5D4" modified="2014-05-14" version="1">MTSEVKGFQKHSDHQLFHDGNGETMQSTSQANQPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCR2</accession>
    <name>X0BCR2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_15504</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979343">
        <property type="protein sequence ID" value="EXK79950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCR2"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_2_0_1"/>
    <dbReference type="OrthoDB" id="1935484at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000106">
        <property type="entry name" value="MFS transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF65">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="510"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="109"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK79950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="568" mass="64965" checksum="D4FCB4DDDC7CC561" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCS8</accession>
    <name>X0BCS8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979552">
        <property type="protein sequence ID" value="EXK76279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCS8"/>
    <dbReference type="HOGENOM" id="CLU_138668_0_0_1"/>
    <dbReference type="OrthoDB" id="5077292at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="17841" checksum="83D18A6962E586C6" modified="2014-05-14" version="1">MSDIDDTSSVAALSEAVTETASQPSTLNTRSAAAGSIAFATFRGGTIPTDVSLMSKIKIQREDYVPTKWIHRKKRARMSPIDPYGRRLTKVVGNREKGDFWLCNQCDKKKEIPLCALVNSGTSGALRHLRKDHDLLVSEVDSETIESEPPRSTPLSGQPRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDP2</accession>
    <name>X0BDP2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979343">
        <property type="protein sequence ID" value="EXK79936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDP2"/>
    <dbReference type="eggNOG" id="ENOG502QUHS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047583_0_0_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047975">
        <property type="entry name" value="Heme_bind_FMP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040572">
        <property type="entry name" value="heme_bind_FMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="405" mass="43238" checksum="A4EF29F13AD313C5" modified="2014-05-14" version="1">MAPTKESSRAGIHLPKGFQYDEVNFDPTPPPPRDEPDPPLGILDSFTGSWTGPGFNTIFRPNSVSPTTTTFTNPVLPAPPSPPNVSVLELNLTQEDMVFSQPLGKVPNRGLEQQNDIIINGVTYLQTVNDVTNTATGKADGTKTGIHTETGFWLNVPPTKNNPVEGNTLVRLGSIPHGTTINAQGNPPNVTQGAPDIGPRPITPFVIGDKGNTQVKPSQTASLNNTARLPQDLTLFIQQGTITQAILDNPIQILLDINSQLTITETSTFTVSTQLDPTPGGGTANIAFLVGASSQGPNANAVQMDSTFWVETIKSEITVQNYTPGKPLLLQPAYKQGQGKTPPPLPTFSVTPPGPVTGPKTIPVTYTQIQYSQTVFLNFNGLTWPHLSLATLVPSQPIEVDYPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFN1</accession>
    <name>X0BFN1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_14890</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658440">
        <property type="protein sequence ID" value="EXK80616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFN1"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF12">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="57"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK80616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="484" mass="54279" checksum="A82DE151BEFC8BAC" modified="2014-05-14" version="1">MAQRDDKTDIRDVEPQIFQNEYPEKAIPQVEKIDYSGAHEKTDPKEIALVKKLDRWMMPMLWSMYWLNYLDRNAIALARLNDLEEDLNLKGTEYQTCVSILFVGYILGQIPSNMFLTRTRPSRYMGIMMMLWAVVSALTAVAKDFKGLLLTRFFLGLTEAPYYPGAVYLLSIFYTRKEVATRIAILYTGNILATAFAGLIAAGIFHGLDDVAGLPGWKWLFILQGAVTFVIAVIGYFVLPDFPLTTRWLTEEERQLAHNRMELDTVGNKGETSTWKGLQQAAKDPMVWIFCAMAHLHLAANGFKNFFPTVVKTLGFNTTITLVLTCPPYLIAGASTILVSWMSGKYNERTWHITASKTVAVIGFASAAATLNTAGRYVCMVIFTIGTYAVNSLILGWCGSVCGQTKEKKAVAISMVTMIMNISFIWTPYLWPSSDEPRYAIAMSSSAAFSIGTAALAWVAKIILKRRNQKLRAQDSETEVFYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BG85</accession>
    <name>X0BG85_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658435">
        <property type="protein sequence ID" value="EXK80821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BG85"/>
    <dbReference type="ESTHER" id="fusox-w9hiy6">
        <property type="family name" value="GTSAGmotif"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_13_1_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF30">
        <property type="entry name" value="ACETYL-HYDROLASE LIPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="98"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="327" mass="35583" checksum="39D343716B06D379" modified="2014-05-14" version="1">MVSLTEGQKATLSPEAVEFLTKIRHPPLANTLSSFITSPCRVPGLRQGFIEKTAPGETQLIEKHKLQITETLIAGVSVVVIEPPTIKPRKQKKILFNVFGGAFIMGSPSDRAALTMAIELGVRVYSIDYTKSPEVKYPEARDQCLAVYRELLQNGPSGGAPVDPSNIHAMGCSSGAQILVSMLLVARQQGLPMPSAGMYLCTPALDLSGAGDSMVFNSLGRDIMPVSLLTGMVSQNYAPEGINVTDPLYSPIYANYDSSFPPTVITVGTRDFALSHGIRFYWKLRETGVKVELLVSEGMWHGFNWDPVIPESIRARAAVIKFLEDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI58</accession>
    <name>X0BI58_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979356">
        <property type="protein sequence ID" value="EXK78543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979356">
        <property type="protein sequence ID" value="EXK78544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI58"/>
    <dbReference type="eggNOG" id="KOG0593">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017513_4_1_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF1">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE EPSILON SUBUNIT HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="158"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="493" mass="56200" checksum="499F6F26F7354AFE" modified="2014-05-14" version="1">MSLYRQLNKCLIPCHEDAEFLPLSEISARVTEDNIKSEVPVRKRCFSNRSLPRTILKQARRIFSILVLIQEAQAIVDLVCRDNITDEDLPLTRQSISGDDQNVLVSAKTVKAFPSFSLWPREARERDFLNFQWLVQAPVLNALGQHISLDTKCPLPLIDCVMKCKSGPNSVLHKCKIHGAHQSIFKNDPEPYVALKEVNNDEAFEKEKANLELTQSLKHEHLIKLIATCQKGSICYFIFPWADGGDLRDFWKANDTIPRSQELVVWCLRQILGIVSAINALHGKNTRHGDIKPQNILHFLKAHDDAVMDSRGRLILADVGVSKIHREITSMRQDPTNCQQSTVTYEAPEAQSDQREGKPRGRRYDMWSLGCMFLEFTVWLVFDYSTVRSFRKSRRTRDDPKDAFGSFFVQTSDNLIQIHSAVIEAIGHLRGHPLCSGDTALADLIQLIQDHLLQVDVQARTEAPELLKRLESIIHRAEQDGNYLYPRFVDNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJL1</accession>
    <name>X0BJL1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658484">
        <property type="protein sequence ID" value="EXK79063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJL1"/>
    <dbReference type="HOGENOM" id="CLU_741943_0_0_1"/>
    <dbReference type="OrthoDB" id="5109562at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="373" mass="42980" checksum="5F94E903CA582669" modified="2014-05-14" version="1">MTNIDNHRASDSMNRVASTHEYAEDIYSFLMARDKEPLVLYPNYLRWRKPLVQTIFNTSFSFKLETCVLAVNLIDVFASRKGPSTVIVAAHLLGQFDAETDGCIIAIATWQRDMIAHGATQWRALSLLAGTALMVASKYEENQNIQVGMAVIGEILQIHDFTKRQKRRLAIIERIFLQVIDWNLGVPGPLPFLQHFIHERRMRPEAAISGNETNEQYENHHSNQEYARKRASTSNEALVQVVAESCIRIAMTQHDAAWYDPNVMAGICYQLALYVVQSAKPDGYKDLVTEHDARMIYLASRTKLSAWQVRRAIRTLLLYILNDPFSDPRFCWWKMLPEMRCLNNQLLTEENLYLQRLSRSLCHNVYSPESARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJU5</accession>
    <name>X0BJU5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Isoamyl alcohol oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_13506</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979330">
        <property type="protein sequence ID" value="EXK82121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJU5"/>
    <dbReference type="eggNOG" id="ENOG502SK56">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023307_0_0_1"/>
    <dbReference type="OrthoDB" id="160645at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054293">
        <property type="entry name" value="DUF7029"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055647">
        <property type="entry name" value="DUF7223"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22974">
        <property type="entry name" value="DUF7029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23865">
        <property type="entry name" value="DUF7223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935772" description="Isoamyl alcohol oxidase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7029" evidence="3">
        <location>
            <begin position="140"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7223" evidence="4">
        <location>
            <begin position="319"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK82121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="57984" checksum="D8D600F48BD08FDC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKA7</accession>
    <name>X0BKA7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_16059</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="KI979348">
        <property type="protein sequence ID" value="EXK79313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKA7"/>
    <dbReference type="HOGENOM" id="CLU_000288_81_1_1"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="101"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK79313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="460" mass="51471" checksum="76F492DA521122CE" modified="2014-05-14" version="1">MSSSRYLRNLTRLVSGRSGCSVTSISELPKYPTSVARKSSTQAAPILHQYPPTTLEDPLTFPSTTYNTIDENVKVEEEEIAGYDTSRFYPVRIGEVFQGRYQAVTKLGFGSSSTIWLAQDLRDRKYVALKIYVHTSRNHREIPVYETLSPILGKTRHHGGRNIRIFLDSFEMSGPNGRHKVLVLEGTQMSLRDYKEFFRTDGFDENFVKRAVKGLLKALDFLHTEAQLVHTDIHPGNLLLGLDDDSQLQPLVSMAFKSPVARKQVLECRTIYLSKVMHPRPGPILLSDFGEARTGLGPHAGDIMPLTYRAPEVIMSMPWNNSVDLWSVGLTAWDLLGMNRLFTARDGDGGMSDAAHLAELMATLGPPPREFLQRNSGRAADFWDEQVGKWKGLAPIPKNCSLEELETKLGDSSAFIAFLRRILTWMPEDRPTAKVLLQDPWLMTESSTSAKAESLGAEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLT9</accession>
    <name>X0BLT9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLT9"/>
    <dbReference type="eggNOG" id="ENOG502QUFU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057752_3_0_1"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="60"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="309" mass="35494" checksum="0A5AF6BCCC9F3F7E" modified="2014-05-14" version="1">MTQDDIPTSDIDPVLYFTPQTHLSDYSKEMDTEETYAVDDLCASSIRASSCKLLFDGTYSDISIICRGREFKVHRAIVCTQCEWFEKAFTTPPKKRTIRSVTLDQDPDVFQHFLEFLYTGTYTAQRPTASVEAERAKEIQDRLNGYPRCPIEKDIAKDSVPERPIRRSSRLLSTTPATSQTETAAKSPEGSPHEIILAMNLFIVAQTYNVPALQLLCRDRFYTAARNRWVNKTWTDWEATKEFEDVVLDVYGSTKEVNTPLWKALCKLICMKRDGDKMKERMMAVKGEQMYLDDGVARYMLEPRGNESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNX8</accession>
    <name>X0BNX8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Salicylate hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12257</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNX8"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_6_3_1"/>
    <dbReference type="OrthoDB" id="417877at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="9"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK83561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="444" mass="48977" checksum="85BCC292D813CEF8" modified="2014-05-14" version="1">MAKPSRNEIHVAIIGAGIGGLALAMALHKKDISFTLYEDAKEYSAVGAGIGFAPNGMRTMDLIEPGFRPLYEAICVGNKGEKAQDIFFEGMLLEEGLGRDKPWYGHSGWGHPDYIRKSAHRKTLLDIMTSFIPIENVKFNKRLTNIEQRPDGVTLSFLDGTTAECSVLAGADGIKSTVRANVLEQYPSQIAPVYAGAYCYRAVIPMSEAYEILGDLTDVAKFYFGPKRSAVTYRITGGDEFNYLLCVADSPDGWKLKGAVTEAISHEAMMADFEGPGVDDRFRQLLAKAKPVKWGFFHHFRTASYYRDRVALVGDSAHASLPFQAAGAAQGLEDALVLSNVLAEVAKIPERGAELAPFIQAGLSAYDSVRRPRAQKQLEQAAEVGRMIFFQHEEAGDDMDKILPRLQQGRFNWLWFHDMNDDAQEAVKRMQKEISVGGPSVARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPK2</accession>
    <name>X0BPK2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658435">
        <property type="protein sequence ID" value="EXK80823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPK2"/>
    <dbReference type="HOGENOM" id="CLU_021599_8_2_1"/>
    <dbReference type="OrthoDB" id="3525185at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF6">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="471" mass="52731" checksum="6E860DB1901A5C06" modified="2014-05-14" version="1">MVGVPKSKGCLLCLQRSVKCDEERPSCAQCRRGGRACPGYVREMKFVDEGPKVRCSRRKAHTSGTISILRNGPKANGGHNGDPIQYLRKGRPDGRLDQPSTFKAERDQILSSFVSAMFPLGSSTAQISFLGSWLWHLPPRLGSSAVLDHAALSVAWAYFAKVYGDSLALRNAELFYLCAVRSLASALDDAKEQLSSNVLCATVLLGHFETFVNVSYAWIRHAGGAARLMQLRGAEKCYESAFEYSMFLACRGAIISEALASGQPCILESESWQKIPDGLIEFPLLPASPNMYHRIFSYFALIPGLQNRMILCNRATSDETRSSLFSTAQRLQQDMRQWYQEYTSQESNLRKPRAISPISEGYPFQSQYAYHDVMSATIITAYYAYLIVLNQSMALFDACDGETLENQELVTAICMSVDYCLHAGYCGTQTMRFALPIAHSVLPRHYDQWTKKWMDKFDAIMEATMIQPLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPY3</accession>
    <name>X0BPY3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658431">
        <property type="protein sequence ID" value="EXK80978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPY3"/>
    <dbReference type="HOGENOM" id="CLU_976713_0_0_1"/>
    <dbReference type="OrthoDB" id="3778483at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="322" mass="37938" checksum="997530265661E722" modified="2014-05-14" version="1">MEDTTAPPITTRTAYIRTIIDKDKEREYYESCWANLRMLLWSWVGQKVHNDPAGTGARRLRSSPPSGLRHHYIIGHSNPFDNFILEWLLENTGPDSWRMTRDDFEVYLSEAQMKDPTNRELLQKLEQERVKITVVDSSITTEFETKDVCDGVMLTKSDYVLETSLERGSSCWITTDVLYRDSLRHGHPQRYNTEELAKRYYHNRLKNKMGHTQRSCSYPHGKSDAWKFDHAEDWKNYACKSCGQRCKRSKGCKITGEDWAKRKDVIAWDEGVDTSAPRPPEFERDWRMLTAEDICNYWGTDPMSYERFRNWKWKSVDTFTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ45</accession>
    <name>X0BQ45_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK83996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ45"/>
    <dbReference type="eggNOG" id="ENOG502RPDN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045008_0_0_1"/>
    <dbReference type="OrthoDB" id="3469466at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="26"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="395" mass="46098" checksum="F8D5230E91B67031" modified="2014-05-14" version="1">MALVPYTKQQLDDCILMPHEPSTSEFHVFNKLPYDLRHKVWESSLLNYRHIKVLLADDNNWEFSIWNCRHRKVFLVDDDDEKQYEIFVKKSAAYHALLNTTSESRNVAKTFYRVQMPCRRMGPDGSVDGTLFLCPELDTIQVETHCCSLQHFEKFSDAIFTADKHNIGLVNLALDCEFRHIDGLFSLDQNEHTLFTDAIRRIEVLTFVGRVAKPELLMYGSDLRVVNSSPRFVDKRIDTESYDRGVFNYESGLYENELKAVHIGKEDPRRGYYSFCLLMEELKIPEDVYKSNLTNELFMLTYNYEPEFIPTNGDPHEYRLAYNNSQREYREYNQGPPPAIGFWLFPLSVIGPFFLDNLNPLTGLPSDRSEAKMVKERVVDVSECDSSFCFYHPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTN4</accession>
    <name>X0BTN4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658415">
        <property type="protein sequence ID" value="EXK82278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTN4"/>
    <dbReference type="eggNOG" id="KOG0806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_2_0_1"/>
    <dbReference type="OrthoDB" id="412018at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07197">
        <property type="entry name" value="nitrilase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050345">
        <property type="entry name" value="Aliph_Amidase/BUP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674:SF16">
        <property type="entry name" value="CARBON-NITROGEN FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G02350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674">
        <property type="entry name" value="NITRILASE C965.09-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="294" mass="32525" checksum="CF55BEFE69E7D76F" modified="2014-05-14" version="1">MAPVYKVAVIQFEPKAIVVAENFAKAESYLRSAASKGCDIAILPEFHLTSWVPEHPDFISASKTSTGYLSKYQALAKELNMNIVPGTICEVHAVPDSKDEELRNMAYFLAAGTGEICGSYQKKNLWHPERPHLTSSTHTPHNAFDTPLKHADGRPVRAGMVICWDLAFPEAFKALVNDGADIILIPSYWFMDDNGEEGAGLNPDSERIFLNCTLTARAFENTAAIVFCNAGGLSCVNMPILGALGRIEVGEEKMEIVDVDLDVLRVAEETYKIRMDMKSEGWHYKYNMNSDSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUH2</accession>
    <name>X0BUH2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979330">
        <property type="protein sequence ID" value="EXK82149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUH2"/>
    <dbReference type="HOGENOM" id="CLU_2996554_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="57" mass="6434" checksum="DEF02526E052AD98" modified="2014-05-14" version="1">MPVMLQEAQNFASPEFKSDSPNTLSTIVECFKPKRLTLTVQDDAGPRQQRNRKPEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW37</accession>
    <name>X0BW37_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sterol 24-C-methyltransferase</fullName>
            <ecNumber evidence="11">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Delta(24)-sterol C-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_12656</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the transfer of methyl groups from S-adenosyl-methionine to the C-24 of sterols.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Steroid metabolism; ergosterol biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10 11">Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW37"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039068_5_3_1"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003838">
        <property type="term" value="F:sterol 24-C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030384">
        <property type="entry name" value="MeTrfase_SMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013705">
        <property type="entry name" value="Sterol_MeTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF1">
        <property type="entry name" value="HYPOTHETICAL LOC100005854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08498">
        <property type="entry name" value="Sterol_MT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51685">
        <property type="entry name" value="SAM_MT_ERG6_SMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 10 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 11" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="5 11" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="2 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase Erg6/SMT-type" evidence="12">
        <location>
            <begin position="81"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK83138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="381" mass="43160" checksum="1671D47C9FE5D1F5" modified="2014-05-14" version="1">MSSSELISYDEAQNSAFDNVLHRKSKESKGGMRAMINKDNKAHAAAVDEYFQFWDNKKAEDEVEAVRQERTDNYASLTRQYYNLATDLYEYGWSQSFHFCRFAYGEDFNRAIARHEHYLAHNIGIRPGMKVLDVGCGVGGPAREIVKFTGAHVTGLNLNEYQVQRATIYAEKEGLSDKLRFVQGDFMKIPFPDNSFDAVYAIEATVHAPSLEGVYSEIRRVLKPGGVFGVYEWLMTDTYNNDDLEQRRIRLDIEQGDGIAQMFKIDHGLSAIQAAGFELLHHEDLAATDDGTAPWYWPLDSDMRYAQTIGDFFTVLRMNKWGRLVMHNVIGALEACWIAPKGTRKTADSLGQAADALVEGGKRKLFTPMYLMVGRKPEESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWD8</accession>
    <name>X0BWD8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWD8"/>
    <dbReference type="eggNOG" id="ENOG502SP1N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065608_0_0_1"/>
    <dbReference type="OrthoDB" id="294702at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="281" mass="31729" checksum="24721B22B3A17527" modified="2014-05-14" version="1">MAQATQNTITKFEIVGNTGSSYPLIIFFHGSGDSCKSWGALAELLRPAYHLLLWDRQDPYVRTDVAISELLGFLDSRDTPKQYVLIAHSYGGTFARLFLEARPHQVAGIVLAETGAEPTIDARLEQRQYDKKILGNKPLVVIRGNTLKWKQLQYDQAIAAEQNLASPTLLMQKKLLDATDKEDERLKKAQLQLSRNNRYVHIPDVSHDVIIEKPEAVREAVCWVMEHLQTGEGEVREEEIQVQARGEDETVAKKSFGDRLRGAKKMSLRGSLSKLFKKSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXU3</accession>
    <name>X0BXU3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pectate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_12055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXU3"/>
    <dbReference type="eggNOG" id="ENOG502RYST">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021894_2_1_1"/>
    <dbReference type="OrthoDB" id="1637350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF18">
        <property type="entry name" value="PECTATE LYASE 21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936797" description="Pectate lyase domain-containing protein" evidence="5">
        <location>
            <begin position="18"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="6">
        <location>
            <begin position="54"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK83718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="328" mass="35096" checksum="20928C37D33328EE" modified="2014-05-14" version="1">MMRSALISLIPAFLATACPVPQASESAGSVVSSGSCGAAEVDELVGYGAKTTGGSGDPVTVTSCSELTSALSNGGVIHIDGQLTGCDIMNVNSDTTILGVGSSSGLTDSGFRIKKADNVIIRNLAMKNPPEGMDLIDIETSTNIWIDHNEFSAEGIAGDKDFYDGLLDAKRGSDFLTFSWNKFSDHWKASLIGHSDSNGDQDTGKLHVTYHHNYWSNINSRAPSIRFGTAHIYSSCYEDLPTSGVNSRMGAQVLVETTAFVNVKRPIVTNLDSKEDGFAIEKDNPFEDSETQITQEKDFVPPYDYTTDSADCICEYLKENAGTGVINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ04</accession>
    <name>X0BZ04_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH-ubiquinone oxidoreductase complex 1/LYR family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ04"/>
    <dbReference type="eggNOG" id="ENOG502S4S4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141157_3_0_1"/>
    <dbReference type="OrthoDB" id="10258445at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090324">
        <property type="term" value="P:negative regulation of oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20265">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045296">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052000">
        <property type="entry name" value="ETFRF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024:SF0">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024">
        <property type="entry name" value="GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="8185" checksum="92F67128195214BE" modified="2014-05-14" version="1">MSLNPQLRRQVIAIYKELLYLGREYPLGFDYFRPRLHKAFISKAGERDEDKIRQGIAQAEYVKKEIEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZB7</accession>
    <name>X0BZB7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZB7"/>
    <dbReference type="HOGENOM" id="CLU_3279505_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="41" mass="4696" checksum="795AB85C03278B31" modified="2014-05-14" version="1">MLFAHSKLQDGRSNLQGAGKVYPMSRMVKSRNSFAFSYWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZH4</accession>
    <name>X0BZH4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphoketolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_19301</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XFP family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979698">
        <property type="protein sequence ID" value="EXK75937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZH4"/>
    <dbReference type="HOGENOM" id="CLU_013954_2_0_1"/>
    <dbReference type="OrthoDB" id="2532903at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02011">
        <property type="entry name" value="TPP_PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005593">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018969">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019790">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018970">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019789">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_ThDP_BS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003617">
        <property type="entry name" value="PRK05261.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003619">
        <property type="entry name" value="PRK05261.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273">
        <property type="entry name" value="PHOSPHOKETOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273:SF0">
        <property type="entry name" value="PHOSPHOKETOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03894">
        <property type="entry name" value="XFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09363">
        <property type="entry name" value="XFP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09364">
        <property type="entry name" value="XFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017245">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60002">
        <property type="entry name" value="PHOSPHOKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60003">
        <property type="entry name" value="PHOSPHOKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal" evidence="6">
        <location>
            <begin position="23"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal" evidence="5">
        <location>
            <begin position="601"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK75937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="816" mass="91740" checksum="9838074CE0C32E06" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZK3</accession>
    <name>X0BZK3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11898</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZK3"/>
    <dbReference type="HOGENOM" id="CLU_001570_14_2_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK83949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="364" mass="42030" checksum="2117C39AB9F38458" modified="2014-05-14" version="1">MNLSFVKSLSSNLSKIHLLLIALAITILTYLLLSTLLSILRSVRSPLQRIPGPWYAPLTTVHLRYLFSTGEIWKLVQHSHAKYSPICRLGPRHIWVSDKESLKQILSTIDLPKVAIYAEISRDRTSPGLFGEIMGKSSFSKGFGQVKRNEASGNSQMDETWKSIPRAIFDGLADRYKYVYIKRFLRRIGCNVEFDWPKQMTMRSKAIDSIVRQRSDEKQHSPDLLQHLIENGKRLDNEETMNSRDILDQMSEILLAGSETTYLDGTHADFVSQYNRVLSFLCRKTLLYRHQVSLLALILSKMIGYRTKSQPLHSFSWAEMRMIAANLLARYDITEVPGHVVDFRQFITMQFHTGHWNVILKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C037</accession>
    <name>X0C037_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C037"/>
    <dbReference type="eggNOG" id="ENOG502SFBG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061843_0_1_1"/>
    <dbReference type="OrthoDB" id="2444812at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="279" mass="30216" checksum="F80E296D82D5E3C6" modified="2014-05-14" version="1">MSSPKPSAGVEEPAAQSPKPESPKRDGATEPVEESSDREDGEASESPEEPNSAPDDKDAPPLPNEPTPDGPPLPSEPVPGGPPLPNEPAPQQEDDGWDCQWDPNTQAWFFVNRFTGKSQWDNPRITTSAPIPAAPGTAPGVPQPPASEKPVAGGYNPAIHGDYDPNAWYAKCTQEEDQIATTSAGITDPAEIYAATATFNRFTGQFQAAGQGPERHSDEAKSKRQMNAFFDVEAAANAHDGRSLKAERSGKKPSKAELKQFKEKRRARKEEKRRAWLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0I7</accession>
    <name>X0C0I7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08979</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ankyrin SOCS box (ASB) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0I7"/>
    <dbReference type="HOGENOM" id="CLU_000134_18_0_1"/>
    <dbReference type="OrthoDB" id="195446at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045732">
        <property type="term" value="P:positive regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051573">
        <property type="entry name" value="Ankyrin-SOCS_box_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24136:SF15">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24136">
        <property type="entry name" value="SOWAH (DROSOPHILA) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="119"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="152"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="249"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK87641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="348" mass="36666" checksum="CB7520C51988ED4B" modified="2014-05-14" version="1">MSAPLMQTCPCHAPGDDPAEITTLHQAAFHQNNQRLEELLQDNADVSATQTPRDFTPLHYAVQFGDEKSVQLLIDAGSNVSARSYDGVTPLHNTSAGGNVRITEMLLKAGANVDSRNIDEETPLHVVSLFGETQITKLLIDAGADVSAKDCYGSTALHIAASHEHIGILKALLDAGADVNAMNNNGDSVLHHAMSDGPECIKLLIDHGANIRLKGEGGDTLLHRAAQSSSELVRDLVKGEVDLEATNDEGATALHCASAWGETASMQIMIESGANVNAANNDGETVLHIVAGNPSLRSGRDSGTKAKLLIDAGAYIHAKAKSSKTPLDYAVDCEGKAVEKVLREMGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C180</accession>
    <name>X0C180_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_11309</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C180"/>
    <dbReference type="eggNOG" id="ENOG502R3ID">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_2_1"/>
    <dbReference type="OrthoDB" id="5393606at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF114">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06620)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="26"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK84519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="356" mass="38814" checksum="587B86D369D5CDDC" modified="2014-05-14" version="1">MTESQGSTVNSVAICFAVISFCAVVLRLWARTFIVRSLGADDYLICVGAILSWCFIGCTIASVQHGLGSHYEDVIKRGTDNFIAYLQIVWLSSIFYNACLGFIKISVLALYTRLGDKMLRKTAFVMMGVVGCQAGANVLACIFQCSPVPAAYDITILPEDKKCVDINAFYLANAAVNIFTDILTYTLPIPLVARLRVPRRQKISLAIILGLGLFACVSSIIRITYIPKMLSSSDQTWVISDAMYWSVIETNIGILAASIPSYKAIAKKYAPRLLGSSGMSSSRKLSGFKQMPLELQGGSNPGTGAPKSTFETNIKNGLEDNSSEEVLVMPSGRIGVKTDITFRYENNLENGTQSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2G5</accession>
    <name>X0C2G5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10711</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2G5"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014021_0_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="607"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="641"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="825"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="318"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="393"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1045" mass="113282" checksum="03825A507F321017" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C313</accession>
    <name>X0C313_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">O-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_10364</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C313"/>
    <dbReference type="eggNOG" id="ENOG502RZAN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067676_7_0_1"/>
    <dbReference type="OrthoDB" id="4863010at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43167">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43167:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK85568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="29087" checksum="552F1D203B7E4ABA" modified="2014-05-14" version="1">MTLTCHMIRHIKAHSMDLSPPLFLIQSIPITYDSQSISTHVMSDQDRIEQALASVVAAPATLQLLRELHSEALAEPAYVSTDSQPVSAALDRFVALEPEKCAIVYLLLRASGATNIVEAGTSFGVSTIYLALAAKQNALLKNVSAKVIATENESTKAIRAQENWKRSDSGDDVNGCIDLREGDLKETLKTDLPEPIDFLLLDIWSTLALPTLQVVQPRLKKGAMIVADNIISGAAGYTDLVDYLSDKNNGFRTTTAPYDGGLLIAVYTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3D9</accession>
    <name>X0C3D9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4385 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979398">
        <property type="protein sequence ID" value="EXK77292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3D9"/>
    <dbReference type="eggNOG" id="ENOG502S5KA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079668_2_0_1"/>
    <dbReference type="OrthoDB" id="2589819at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025494">
        <property type="entry name" value="DUF4385"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14328">
        <property type="entry name" value="DUF4385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="19476" checksum="F86634253D556959" modified="2014-05-14" version="1">MAPEMAVSRSKAKPLMETISEAHRMSYRIGRGEQGVLTFEPYKSAILPLWRFRTVPIARQSAEDLWAKFNEFKDQHDFVGMDMTRKFIQMGMTRAKRYANHAGGRKYKKGTREELPKSDEHLDKDEKETASLIFRGYWERCKEDEEYQNLKEEFLKKQKDWKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3P3</accession>
    <name>X0C3P3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658613">
        <property type="protein sequence ID" value="EXK77392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3P3"/>
    <dbReference type="HOGENOM" id="CLU_100997_2_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436:SF1">
        <property type="entry name" value="ESTER CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="POLYKETIDE CYCLASE SNOAL-LIKE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="14214" checksum="B03F2EACCE72E1B9" modified="2014-05-14" version="1">MNLNNKQIVTDAYQRIFGDLDASAVDDYISKDFVQHNPTIADGPAGVKQLVQKLVSQGVQKQTIEFKHVVAEGDTVILHTRYEMAGHEWRFIDIYRVKNDKLVEHWDAMIQWPETRANNNPMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4A3</accession>
    <name>X0C4A3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cyclin B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_07884</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin AB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4A3"/>
    <dbReference type="eggNOG" id="KOG0653">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5590282at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044772">
        <property type="term" value="P:mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20568">
        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20512">
        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000001">
        <property type="entry name" value="G2/mitotic-specific cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000005">
        <property type="entry name" value="G2/mitotic-specific cyclin B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046965">
        <property type="entry name" value="Cyclin_A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0195">Cyclin</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="251"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="8">
        <location>
            <begin position="344"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="348"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK89200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="480" mass="53915" checksum="BB071E1650CF1CE7" modified="2014-05-14" version="1">MPPQARATRTRLAGNENDENSSTTRLTRAQAAALKVDELSMPAKAALQTKKSTVNGTAASNTRKRAALGDVSNVGKVDGVAGKKAKGLVSKAAQPTGIEKKTARPTTRTALGSKPTNSKTQSGSGTINKRKVVTDTANTKIKAPVNENEHPSKKQHLIPEERERSETPVEVEVEKPEVSLDKAEVQDAPFEYPPGVKDLDSEDLEDPLMVAEYANEIFEYLRDLECKSIPNPQYMSHQDELEWKTRGILVDWLVEVHTRFHLLPETLFLAVNLIDRFLSEKVVQLDRLQLVGITAMFIASKYEEVLSPHVENFKRIADDGFTEAEILSAERFILSTLNYDLSYPNPMNFLRRVSKADNYDIQSRTIGKYLMEIGLLDHRFMAYRPSHIAAGAMYLARLMLDRGEWDETLSYYAGYTEDEIEPVVHLMVDYLARPVTHEAFFKKYASKKFLKASILARQWAKKNAVLFGITDVHLSLDELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6U0</accession>
    <name>X0C6U0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658518">
        <property type="protein sequence ID" value="EXK78447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6U0"/>
    <dbReference type="HOGENOM" id="CLU_1012082_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="2"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="275" mass="30737" checksum="CB22B6D8E92CFABF" modified="2014-05-14" version="1">MAPSFISLPPEIISMILTYLPPEDVLRIGLTYKRLNILSLSPIGCCHNSEIRYIMIEKRNLASPVSSSIIMSLASSAQELNIHPFALSSFDILLNLRRSPLGAEWKASSESLQSIIPFILIPIAACKLQVGGLNISARLLTRDVRCIIPSLLPPRLRCSSSLTQRPALYDFTSETCIFGGNLKNVTIPLLKRLAFVMEEYEEKDLKDFLLRHAKTLVTVDLGSFMTKNPIKKRPIVQFVIEELQVPCLLGVEKNGSDHHEALHCRDDDDDAGLWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8V4</accession>
    <name>X0C8V4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8V4"/>
    <dbReference type="eggNOG" id="ENOG502RKZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_990607_0_0_1"/>
    <dbReference type="OrthoDB" id="4882315at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="283" mass="31035" checksum="FEB8B858D5DAB560" modified="2014-05-14" version="1">MTNQTPLYGNKFAELVAQDVSNPLPAENAVNAKLTSIDGTGTAALVSRLYVPEDTKRYGGFGLIFKDDSTYDDFKWVQFVTRQLVIDGAAQTGSLSNKTNKPAYQLVNSTEDITDFATGSGAPNWNTCWGVDSKLTDVFFASTHEYVKSDALKVNGIMDTPSVLIGKIPKPWDRDSYQDAPDDLVDMKELATGPGTSRAYFSDYLVKKVDGGGHRIYARFDLSLSWNAGEGDKKNFELSSLNSTATNAFLNCHRAALQHTTRPLKEGSVSKQPYLDFLNSIVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8Z9</accession>
    <name>X0C8Z9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MYG1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8Z9"/>
    <dbReference type="eggNOG" id="KOG2948">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051576_0_0_1"/>
    <dbReference type="OrthoDB" id="10265310at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="MYG1_exonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215">
        <property type="entry name" value="METAL DEPENDENT HYDROLASE - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215:SF1">
        <property type="entry name" value="MYG1 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="MYG1_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="39228" checksum="7588D51F739DB61B" modified="2014-05-14" version="1">MLRRLFTTMAESASKRVKTTGNGPLIGTHNGHFHADEALAVHMLRRLPAYRDASLVRTRDPAVLATCHTVVDVGGEYDAEKRRFDHHQRGFTTTFPGRPTKLSSAGLVFLHFGRAIVAERLGQPEDSADVELIYEKLYENFVEALDAHDNGISVFDPAGIAAAGLEKRFSDGAFGLGAMVGRLNPKWNDPTPSDPAEAQAAEDAKFNEASNRIGEEFDRDLDGYAGSWLPARTIVQEAFTKRTQYDEQGRLLVLEGQSVPWKDHLYTLEDGTPSVLYVLYAEKPEPGAKWRIQCVPESKDSFVSRKPLPEAWRGFRDAELDGISGIPGCVFVHAAGFIGGNKTFEGAKQMALKALGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CA66</accession>
    <name>X0CA66_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CA66"/>
    <dbReference type="HOGENOM" id="CLU_3260557_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="42" mass="4452" checksum="D0F6DAE40C4B3575" modified="2014-05-14" version="1">MQCNSKDKLDKVSTGETGIQPLLDGTLGGPIANKNNCHKVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAN6</accession>
    <name>X0CAN6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658462">
        <property type="protein sequence ID" value="EXK79732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAN6"/>
    <dbReference type="HOGENOM" id="CLU_3087275_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936891" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="52" mass="6169" checksum="CA909CFCCB0133F1" modified="2014-05-14" version="1">MTGAPWMRCHETALLALILRRLVLNYLSDSNLYEEFKTLIVEYRTSHAEDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBH7</accession>
    <name>X0CBH7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Agmatine deiminase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBH7"/>
    <dbReference type="HOGENOM" id="CLU_037682_2_0_1"/>
    <dbReference type="OrthoDB" id="544103at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047632">
        <property type="term" value="F:agmatine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004668">
        <property type="term" value="F:protein-arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009446">
        <property type="term" value="P:putrescine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007466">
        <property type="entry name" value="Peptidyl-Arg-deiminase_porph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31377">
        <property type="entry name" value="AGMATINE DEIMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31377:SF0">
        <property type="entry name" value="AGMATINE DEIMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04371">
        <property type="entry name" value="PAD_porph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="44442" checksum="F5F6B021B5E45EB0" modified="2014-05-14" version="1">MFRTLQRSIKAPVKGFMDPGQIQRISGRYRMPPEWQKHSQTLTAWPSPASIVDEKILRQARAEVSALSNAISRFEPVTMFARPEDVHEASATVSDNVTVRPLAVSELWIRDTGPVFVHGTQNGCSTGLKLNFNYWGAKIPSSGDEAVAANIEIPEASVIDRKDEKDGSAPQGSVIPIIDGGFTSEGGAIEVDGDGTLLATESSIVNENRNPRKSKKELEELFEKYFGIHKVIWLTGVKGYDITDFHIDAFARFIKEGQVLLSRPSERADPLVIQAYKEAKEILRNATDHRGRRLEVFEVEEPHPSDLPGENWDHFDVTVASYANYYLPNGGLIMPRFGVGKLDDDAYELFRQHFPDREVVQVDLNILPKLGGGIHCATQQVPMEGWFGRAVRRGELKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBN1</accession>
    <name>X0CBN1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08411</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBN1"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_16_5_1"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="13"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="338" mass="35626" checksum="3B13BAEF5F14DF44" modified="2014-05-14" version="1">MATNNAAYLVAEKAPLEVKPAPFPEPKDDEIIIENHAVALNPVDSAQQRLGPSIFPWLKFPAILGCDVAGRITAVGSGITKYKVGDRVTGYNMGTFQEYVPVKEYLCAKLPDSIGFAEAAVLPLCLSVAVKTLFHPGYLALDLPTTETKANGKVILIWGGSTSVGCNIIQLAKAAGFEVITTASPKNFDYLKKLGASQTLDYNSPTIKEDLLTAVKGKVVAGAIANGGLNISVYPSIVETCAAVALSSPDNCKFVPLTMVPRFPVPDGVETKFVVPLATDKDLASWIFNDYISEALASGSFVPAPEAEVVGHGLGSLQTALNTLDAGVSAKKIVVTMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBR1</accession>
    <name>X0CBR1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_15331</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658452">
        <property type="protein sequence ID" value="EXK80112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBR1"/>
    <dbReference type="HOGENOM" id="CLU_028200_6_3_1"/>
    <dbReference type="OrthoDB" id="5113978at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF143">
        <property type="entry name" value="EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="33"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK80112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="384" mass="43177" checksum="C765995DF38385D6" modified="2014-05-14" version="1">MTSCSAPVRHDAKHLSTITIILTIVSWVLLIQRFFCKILAKLPLGLDDWLVLVTAISGVVSSTININHVLPSGLGRDVWTLKPDQIYQFGFYFYIVSVLYPFQVTTLKLAMLCLYLRIFPSEGIRKVIWGTAAIVCAFGVTFILASTTACRPISHIWNKWDGEHEGRCVDIALIAWTNAAISIALSLWLIVIPLWKVRSLEMKRHKKVGVAIMFILGTFDTIVSILRLSSLISFRNNVNATLSYAQVIKWSTIEINVGLYCVCIPTLRLVLVEVYSKLLATRRALSGGNEYGTSNSRRRVHGWPRNTIITSRIEMDPSGRERWQHGSRVNDNGDKIYRFRQALKPGNAIVGTKTSMVTYDETDEEELISSAQACQKELRAGRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD48</accession>
    <name>X0CD48_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD48"/>
    <dbReference type="HOGENOM" id="CLU_754480_0_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="355" mass="40163" checksum="481C3EB2094B6621" modified="2014-05-14" version="1">MAEGFEVPVHPGVFGLQMPFDAMLELAEIVCDVSLEDGKGTATGIYLDGISFFLYPTSYKTLPGRQPVVQWHLKEKTLDDEGDRDPEIPPPTEMVFWDTVRRPWCSWVRRARRKYHNEPQYSHTEVEKPNIEAYLNSLTLDSSAGGAKAEGSIGFRLRNGHKRELDDQKVLTYKQVLRISQNMPVIIYDTQRQNERAWMVSQLSMILELFNIWVQQKGLRGIQYATASADGGAAAFNVLANRNYSERTTIDKMADEDPSDVKISGIIKRLYGRIQKMRSINGDSDEGARGTLSLGRCTMKGWDWLELVDGFERAEKKPAQVVDRARARLTATEMNDKALMMAMGSERTSKPHSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF10</accession>
    <name>X0CF10_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF10"/>
    <dbReference type="HOGENOM" id="CLU_2867694_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="64" mass="7101" checksum="54276604C695FB55" modified="2014-05-14" version="1">MERTQAIVNRFNRAPDVENQLLMRSWTNKVTLCGVPNHPTIGASTSKNTVRQKSHGHGRGHGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFB7</accession>
    <name>X0CFB7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_05304</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFB7"/>
    <dbReference type="eggNOG" id="KOG0897">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003143_1_0_1"/>
    <dbReference type="OrthoDB" id="109543at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23802">
        <property type="entry name" value="UBCc_UBE2Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051838">
        <property type="entry name" value="ARTD_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21328">
        <property type="entry name" value="POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="1008"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="889"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="951"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="896"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="917"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="964"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK93095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1199" mass="134634" checksum="17D319FEF5E7F26C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGJ5</accession>
    <name>X0CGJ5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_07416</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGJ5"/>
    <dbReference type="HOGENOM" id="CLU_027074_2_0_1"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848:SF4">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="5"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="103"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK89959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="228" mass="25862" checksum="D6ADB7322A0C9009" modified="2014-05-14" version="1">MDSPSISQVAPNLFVGNVASSMNRNVLRHHNITAIVSLLDGPYSKWESPKNRQIVPQECHLFVPCLDNSTMDILCLLDDICDFIDLQLDRHGSLRSPSSFISEEFDPDTASTIESEDSARESNVLIHCRLGMSRSASVAIAYLMRQRQLSLDVIIAEVRARRKVKPRGNFMDQLQVWQAVEYQLWEDNQKRIPKAPYQSYLDGRAVRLAAKGLTGNEPIVPLCDWDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGN1</accession>
    <name>X0CGN1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Xylan 1,4-beta-xylosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_05468</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGN1"/>
    <dbReference type="eggNOG" id="ENOG502SM8A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016508_2_1_1"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09000">
        <property type="entry name" value="GH43_SXA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF12">
        <property type="entry name" value="BETA-XYLOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="7">
        <location>
            <begin position="327"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="5">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK93341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="538" mass="61196" checksum="DE1D292385754DBA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGY3</accession>
    <name>X0CGY3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGY3"/>
    <dbReference type="HOGENOM" id="CLU_149463_0_0_1"/>
    <dbReference type="OrthoDB" id="5094362at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="112" mass="12879" checksum="30E2CDBCB72EE5D5" modified="2014-05-14" version="1">MASPAMVRYFRDHEISIPKPHLDYVMDHQGNRNAIPLVMITTRLRHLRDRLEGQPASEVEERIAPMVESIRFRQSGKHQFKRTLYAQDPSLSVLAAARSFIPELIEVSKIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHE8</accession>
    <name>X0CHE8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHE8"/>
    <dbReference type="HOGENOM" id="CLU_157438_2_0_1"/>
    <dbReference type="OrthoDB" id="5239630at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019034">
        <property type="entry name" value="UPF0390"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09495">
        <property type="entry name" value="DUF2462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="87" mass="9410" checksum="460DEBE41F49C69E" modified="2014-05-14" version="1">MAQGTVKKLGRATPAKITHSKRQASKVHKPKKTKASVDKVHKKFTSGMTARTEALLGERAGHLELLGQGKKKTDKKTTQKGGSKKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIE7</accession>
    <name>X0CIE7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylserine decarboxylase proenzyme 2</fullName>
            <ecNumber evidence="12">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 2 beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 2 alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="12" type="primary">PSD2</name>
        <name evidence="16" type="ORF">FOQG_06570</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="12">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit. Interacts with pstB2. This interaction may be a means to structurally tether the donor membrane (ER) harboring PstB2 to acceptor membranes (Golgi/endosomes) harboring PSD2 during PtdSer transport to the site of PtdEtn synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Golgi apparatus membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Endosome membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The C2 domains have an essential, but non-catalytic function. They may facilitate interactions with other proteins and are required for lipid transport function.</text>
    </comment>
    <comment type="PTM">
        <text evidence="12">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="12"/>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIE7"/>
    <dbReference type="eggNOG" id="KOG1028">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2419">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04024">
        <property type="entry name" value="C2A_Synaptotagmin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000445">
        <property type="entry name" value="Phosphatidylserine decarboxylase proenzyme 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000198">
        <property type="entry name" value="Phosphatidylserine decarboxylase proenzyme 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000295">
        <property type="entry name" value="Phosphatidylserine decarboxylase proenzyme 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00663">
        <property type="entry name" value="PS_decarb_PSD_B_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033179">
        <property type="entry name" value="PSD_type2_pro"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF17">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="12" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5041025872" description="Phosphatidylserine decarboxylase 2 beta chain" evidence="12">
        <location>
            <begin position="1"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041025871" description="Phosphatidylserine decarboxylase 2 alpha chain" evidence="12">
        <location>
            <begin position="1029"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="42"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="279"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="15">
        <location>
            <begin position="530"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="213"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="424"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="631"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1087"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="639"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="675"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="884"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="942"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="1029"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="12">
        <location>
            <position position="1029"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="12">
        <location>
            <begin position="1028"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="12">
        <location>
            <position position="1029"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK91053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1132" mass="126315" checksum="017E252DA283A5EE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIR2</accession>
    <name>X0CIR2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ureidoglycolate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_06879</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-ureidoglycolate = urea + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:11304"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="4.3.2.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIR2"/>
    <dbReference type="eggNOG" id="ENOG502S1JQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070848_0_0_1"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004848">
        <property type="term" value="F:ureidoglycolate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050385">
        <property type="term" value="F:ureidoglycolate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20298">
        <property type="entry name" value="cupin_UAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.480">
        <property type="entry name" value="Ureidoglycolate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047233">
        <property type="entry name" value="UAH_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007247">
        <property type="entry name" value="Ureidogly_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024060">
        <property type="entry name" value="Ureidoglycolate_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221">
        <property type="entry name" value="UREIDOGLYCOLATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221:SF1">
        <property type="entry name" value="UREIDOGLYCOLATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04115">
        <property type="entry name" value="Ureidogly_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK90694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="247" mass="26092" checksum="26F412CEB97C99BA" modified="2014-05-14" version="1">MSVKVNVGNLSLRIGTAPLTQEEFAPFGDVVSNPRPSLLPSKHASEGGSLPYNGTTANQGTAIRYADVSKPQDLLSQAPSSNGRLIMSQFVCEARTLAPASDDASQSEFAVNILERHPFTSQTFAPLASTASSYLVIVAPSLPPSPQDDGLPVPSGEGLPGRGLPDLKGLRAFVATDRQAVTYAAGTWHAPMVALGKKETTLDFLVVQFSSGVDIQDCQIVTFEGQDSKESDIKVRVPRGGRVTAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIW9</accession>
    <name>X0CIW9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIW9"/>
    <dbReference type="HOGENOM" id="CLU_3191360_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="46" mass="5209" checksum="6ECAF30B44DE3DE2" modified="2014-05-14" version="1">MAPNNCTFRVVTGRVENKKNKTKAQNRQAEKLADKTTDKQLKFGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJP1</accession>
    <name>X0CJP1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_04651</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJP1"/>
    <dbReference type="HOGENOM" id="CLU_006926_2_1_1"/>
    <dbReference type="OrthoDB" id="3266505at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF39">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK94645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="769" mass="85758" checksum="6394EA3FA587497D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CK44</accession>
    <name>X0CK44_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Glycylpeptide N-tetradecanoyltransferase</fullName>
            <ecNumber evidence="5 11">2.3.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_04598</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15521"/>
            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12667"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133050"/>
            <dbReference type="EC" id="2.3.1.97"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the NMT family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.97" evidence="5 11"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CK44"/>
    <dbReference type="eggNOG" id="KOG2779">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022882_2_0_1"/>
    <dbReference type="OrthoDB" id="60315at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000042">
        <property type="entry name" value="Glycylpeptide N-tetradecanoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000056">
        <property type="entry name" value="Glycylpeptide N-tetradecanoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000903">
        <property type="entry name" value="NMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022677">
        <property type="entry name" value="NMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022678">
        <property type="entry name" value="NMT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022676">
        <property type="entry name" value="NMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377:SF5">
        <property type="entry name" value="GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377">
        <property type="entry name" value="N-MYRISTOYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01233">
        <property type="entry name" value="NMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02799">
        <property type="entry name" value="NMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00976">
        <property type="entry name" value="NMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase N-terminal" evidence="14">
        <location>
            <begin position="181"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase C-terminal" evidence="15">
        <location>
            <begin position="349"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK94566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="567" mass="64324" checksum="6A8D78D779432D4A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CL15</accession>
    <name>X0CL15_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658405">
        <property type="protein sequence ID" value="EXK83217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CL15"/>
    <dbReference type="HOGENOM" id="CLU_3087273_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="52" mass="5675" checksum="56A47148E1ADCC85" modified="2014-05-14" version="1">MTEAEANRTHLIQATDVFSLSAALHSTVTRVGRLRINGSGRLEQGQRTVVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM45</accession>
    <name>X0CM45_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CM45"/>
    <dbReference type="HOGENOM" id="CLU_3320057_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="39" mass="4531" checksum="EB0584496EC7411C" modified="2014-05-14" version="1">MVPLIVGGHTVRCQQRPTSDSNAHQDYWDEEKFKLLSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMD4</accession>
    <name>X0CMD4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Replication factor A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_05604</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMD4"/>
    <dbReference type="eggNOG" id="KOG3108">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051033_0_1_1"/>
    <dbReference type="OrthoDB" id="25571at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014646">
        <property type="entry name" value="Rfa2/RPA32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF16">
        <property type="entry name" value="REPLICATION PROTEIN A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036949">
        <property type="entry name" value="RPA32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB" evidence="7">
        <location>
            <begin position="76"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A C-terminal" evidence="8">
        <location>
            <begin position="167"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK92473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="277" mass="29464" checksum="818B78072B7471EE" modified="2014-05-14" version="1">MSAYSGFTKTSYGAQGGDDSGGFFAGGSQQGSQGGAGGKSYQDESLRPVTIKQILDAEEAYAGADFKIDGSPVTQITFVGQIRKIQPQPTNITLNIDDGTGMIEVKKWIDVDKQDDADPGFELESHVRIWGRLKSFNNKRHVGAHVIRPVADFNEVNYHMLEATYVHLYFTKGPLGGQGGSNGDGDSMFVDGGGYNDNGGGNAGQAPTKLAGCSGLAKKMFNFMNDTPGGNEGVHLNVITNSTGMSVRDALTAADELLGQGLIYTTVDDETWAILEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CME7</accession>
    <name>X0CME7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CME7"/>
    <dbReference type="HOGENOM" id="CLU_2469137_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="88" mass="9156" checksum="77A8043FED83162E" modified="2014-05-14" version="1">MTPVIAPGGWKAQGTHTCAHTHALAIAIAGRYQATMMSYLEKRQLSGAPGNGPKSGQDQKISLSQNLDSGVADSHPESAGHQVYVAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMJ1</accession>
    <name>X0CMJ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable quinone oxidoreductase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">NADPH:quinone reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_03976</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMJ1"/>
    <dbReference type="eggNOG" id="KOG1197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_1"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:quinone reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05286">
        <property type="entry name" value="QOR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000053">
        <property type="entry name" value="Quinone oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047618">
        <property type="entry name" value="QOR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF13">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="55"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00070796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK95401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="367" mass="39539" checksum="E814818AADBA028D" modified="2014-05-14" version="1">MAQLLRRSLLRTSTISKPLTQIPIQRISRITSHFSTATMAPVPPKMKAVQINKNGGTEVLEFNDVAVPKAGEGQILVKNQIAGLNYIDTYFRSGLYKAPQFPLTLGREAAGTVVDAHSSVKGFENGTRVVFMGTVGAYAEYSVVNASDAVKIPDEVPTDQAVAAYLQGLTAWTFIREAGQVKAGQWVLVHAASGGVGTLLVQLLRIVGAKVIGTASSEEKLALAKKNGAEWVINSHDDVVAKVKEITGGHGADVIFDGVGKVTFDGDLEMIAAKGNLISFGNASGAVEPVSLFRLTPKCVRLMRPVVNGYVSERADLEKYTSELFDLIKSKKLELTIHKVYPLKDVAQAHQDIESRKTIGKLLIKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMS6</accession>
    <name>X0CMS6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04049</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMS6"/>
    <dbReference type="eggNOG" id="ENOG502RZJP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027207_0_0_1"/>
    <dbReference type="OrthoDB" id="5348546at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="115"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK95481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="521" mass="57086" checksum="E25859DD4F8117A9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMT2</accession>
    <name>X0CMT2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMT2"/>
    <dbReference type="HOGENOM" id="CLU_2145972_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="112" mass="12662" checksum="E2D3A24A3B2F2077" modified="2014-05-14" version="1">MLILVPSPANLMNARPEVNNHQLLHHRHHLASRHSNALTPEAHDTHHMTLITTTSNDNAHTHTQLKHSEQGTQRLPPTKILNVLAFWCIPASWDKPEPIAKGPRRLLNPILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMT4</accession>
    <name>X0CMT4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMT4"/>
    <dbReference type="HOGENOM" id="CLU_2573960_0_0_1"/>
    <dbReference type="OrthoDB" id="10385357at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="81" mass="9356" checksum="232E1C0FB98348A6" modified="2014-05-14" version="1">MQILLLFEVRISECTTPSQIGRVLDETTNNYRPEMQSPLGANMGKDNHSQLDLLRQKWPPARVLAWYVPCRLVICNGWVWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPY5</accession>
    <name>X0CPY5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPY5"/>
    <dbReference type="eggNOG" id="ENOG502SKI4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018249_0_0_1"/>
    <dbReference type="OrthoDB" id="5427350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF5">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937840" evidence="2">
        <location>
            <begin position="21"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="576" mass="62948" checksum="7E6E0A4DC724A344" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR11</accession>
    <name>X0CR11_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR11"/>
    <dbReference type="eggNOG" id="ENOG502S09K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071379_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018811">
        <property type="entry name" value="MRX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28002">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28002:SF1">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10306">
        <property type="entry name" value="FLILHELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="203" mass="22959" checksum="75B5899EAAAFF101" modified="2014-05-14" version="1">MRRNLISFNWRPSLRARAPPRINTSYLRAESTQASRIDRITSKLPRRLQRYTSGLRNAPVSHIVSFLILHEITAIVPVLGLFGLFHYTNYVPVEYVTGHFGSYVEDGVGRFERYFTRKGWFGFGQNEEGEASNAATTHPDSKSEDAVERWHSGDGRYKVVVEVALAYAITKALLPVRIIGSVWATPWFAGVLMRAKGIFTSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRN8</accession>
    <name>X0CRN8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_04809</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRN8"/>
    <dbReference type="eggNOG" id="ENOG502S9U8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014924_2_0_1"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF15">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="52"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK93544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="652" mass="72380" checksum="460E8F09F7D5865F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSG8</accession>
    <name>X0CSG8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSG8"/>
    <dbReference type="HOGENOM" id="CLU_215063_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="35" mass="4011" checksum="5F4252DCE52E30D6" modified="2014-05-14" version="1">MSVTADSYDLQFGCTHESFLSEEKRSDGLRVFELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTC7</accession>
    <name>X0CTC7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTC7"/>
    <dbReference type="eggNOG" id="ENOG502QSAC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032323_1_0_1"/>
    <dbReference type="OrthoDB" id="2283785at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039634">
        <property type="entry name" value="Bul1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904:SF1">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="54322" checksum="8BD5075415E5D4E3" modified="2014-05-14" version="1">MSNAASDNGPRSTRPRPAKSGIDIKLDQHWSSKSYTSGSKVTGNVIISTQRDVAYDGFDIFFTGTAYTRVDFVSQYSSANYASRPFMKLRMPLSPADFPSNRVFEAGRTYTIPFHFVVPHQLTLSACNHPVEHEGIRDHHLQLPPTMGFWERNDQSPDMAHIEYGIRAVATKNSEEEGRTLPLDSFHMVKVLPAMPEDAPLDICSKDERYCLSKTKPIRKNLFSAKQGELTTTASQPSAIMLSGNFLNASGTNLKVNFEFSSTSKDVTPPKVNSVSAKLHATTFFSSAPMTQLPNLGSRIKHQSTPSLTYSTTTPVPMRPDTRLTWEDEAPGSRRDSGYDSAFWNEGETSESDDAQRNKKASKYNVRRYATLDIPFNLPTSNSKLFLPTFYSCLSARAYILHLTLSVGPMNTNINLNIPIQVAVENTYDHIDDDELPSFDAAIAEAEEADVDLHLQPRLMQVPDARFQGNSVLPGYEDMRMRAQVAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTM3</accession>
    <name>X0CTM3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_02688</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTM3"/>
    <dbReference type="SMR" id="X0CTM3"/>
    <dbReference type="eggNOG" id="KOG0746">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033361_2_1_1"/>
    <dbReference type="OrthoDB" id="1611972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000079">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1430.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.960.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.960.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000351">
        <property type="entry name" value="Ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.960.10">
        <property type="entry name" value="Ribosomal protein L3, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044892">
        <property type="entry name" value="Ribosomal_L3_dom_3_arc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK97521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="391" mass="44108" checksum="0F88A0FA9E3BEAA7" modified="2014-05-14" version="1">MSHRKYEAPRHGSLAYLPRKRAARHRGKVKSFPKDDPKKPVHLTAAMGYKAGMTTIVRDLDRPGAKANKKEIVEAVTIVDTPPMIVVGLVGYIETPRGLRSLTTVWAEHLSDELKRRFYKNWYKSKKKAFTKYAKKHSENNGASITRELERIKKYCTVVRVLAHTQIRKTPLKQKKAHLMEIQVNGGSIADKVSFGQELFEKPVDISSIFEQDEMIDVVAVTKGHGFEGVTARWGTKKLPRKTHKGLRKVACIGAWHPSHVQWTVARAGQRGYHHRTSVNHKIYRIGKGDADDNAATEIDVTKKTITPLGGFVRYGEVNNDFVMVKGSIPGTKKRVMTLRKTMFPQTSRRALEKVSLKWIDTSSEFGHGAFQTPAEKKQYQGTLKKDLASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTU5</accession>
    <name>X0CTU5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RNA-binding protein VTS1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">RNA-binding protein vts1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_03596</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">RNA-binding protein involved in post-transcriptional regulation through transcript degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer. Binds to RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VTS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTU5"/>
    <dbReference type="eggNOG" id="KOG3791">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017632_0_0_1"/>
    <dbReference type="OrthoDB" id="2155283at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09556">
        <property type="entry name" value="SAM_VTS1_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.50:FF:000033">
        <property type="entry name" value="Protein vts1, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050897">
        <property type="entry name" value="SMAUG/VTS1_RNA-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057327">
        <property type="entry name" value="Vts1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037635">
        <property type="entry name" value="VTS1_SAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515:SF5">
        <property type="entry name" value="PROTEIN SMAUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25479">
        <property type="entry name" value="Vts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SAM" evidence="14">
        <location>
            <begin position="551"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="232"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="517"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="275"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00054767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK94718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="619" mass="66204" checksum="BEE914CEC1E15531" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUN5</accession>
    <name>X0CUN5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_09894</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUN5"/>
    <dbReference type="OrthoDB" id="2993351at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052355">
        <property type="entry name" value="CENP-V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620:SF1">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620">
        <property type="entry name" value="CENTROMERE PROTEIN V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="4">
        <location>
            <begin position="19"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK86177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="178" mass="19745" checksum="2BEA51B854C9464B" modified="2014-05-14" version="1">MFAKYLEKLANAGGPEVTYEAGCHCGYIGLSVALSPPLPKHEVINCNCSICRRGGYLLVYPAYEKVTWHNDSDKLVSRYQFNTKARDHMFCPKCGASIGIDFARVWPEAPRYGISVGDMNHYRRKGLTESLQVRQFNNIDLDSLQYMKLDGLHNAEPAVDLSGKEIDPKAGEAPASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUV8</accession>
    <name>X0CUV8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cryptochrome DASH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_01198</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May have a photoreceptor function.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
        <text evidence="7">Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="5 7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUV8"/>
    <dbReference type="eggNOG" id="KOG0133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010348_6_1_1"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000719">
        <property type="term" value="P:photoreactive repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014133">
        <property type="entry name" value="Cry_DASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02765">
        <property type="entry name" value="crypto_DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF22">
        <property type="entry name" value="CRYPTOCHROME DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="9">
        <location>
            <begin position="5"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="187"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="557"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="563"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="641"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="681"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="297"/>
            <end position="301"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="466"/>
            <end position="468"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK98225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="715" mass="81616" checksum="E30DD86835B2C437" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV19</accession>
    <name>X0CV19_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">37S ribosomal protein S35, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV19"/>
    <dbReference type="eggNOG" id="ENOG502QVMS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049223_0_0_1"/>
    <dbReference type="OrthoDB" id="10052321at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021036">
        <property type="entry name" value="Ribosomal_mS45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S35, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12298">
        <property type="entry name" value="Bot1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="36428" checksum="7BC81082BD87C33F" modified="2014-05-14" version="1">MPPRVRGASTPLAGLDATISLSTRTSSSPFLRTFSTTPCREKMSKGRAQMFEWLNSGNGRNLAEPGNGPNYLGPHNDQPFPLNPLFRSQPVLSDATREIIYEKVTAKGMSLKAVSAEMHIDVRRVAAVVRLKEVEKQWLSEGKQLATPYAKAVMKMLPKTHYNEGEENIPHEPINEIHVHNLTLQQLFTPVSESRHFTREDAAKAFHDNMLSADQRSPQPELIKMEQDIIKGTARPEAVAKFQAVTQADEDRVAKKILNERRREEERTKRVKTDRYEFRFKEINVDDVGRDGRSRKGTGWRYGAPFEDRKRGLVKIPTSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWA4</accession>
    <name>X0CWA4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWA4"/>
    <dbReference type="eggNOG" id="ENOG502T6EH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021109_0_0_1"/>
    <dbReference type="OrthoDB" id="4837923at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="550" mass="60800" checksum="977079CF1373CB04" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWR0</accession>
    <name>X0CWR0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWR0"/>
    <dbReference type="HOGENOM" id="CLU_2015379_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="14008" checksum="37037E6A1AB5A0B2" modified="2014-05-14" version="1">MTDFITQINDRLCCHVVATLSRCPKISYQTPWLKRLVLQRCHDVIGNSFKSLLFKYLRYTSQRIKSAPQLYAASSQREIKITYSQSIPPLQLTHQQPPKTMTTSSPLALQWDHLLAPLAHGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXM5</accession>
    <name>X0CXM5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_04169</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXM5"/>
    <dbReference type="ESTHER" id="fusof-f9fki8">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1516">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_15_0_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152190" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="20"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK95619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="521" mass="57169" checksum="BFAAD54269109606" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYP1</accession>
    <name>X0CYP1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">holo-[acyl-carrier-protein] synthase</fullName>
            <ecNumber evidence="1">2.7.8.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_01831</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.8.7" evidence="1"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYP1"/>
    <dbReference type="eggNOG" id="KOG0945">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031126_0_0_1"/>
    <dbReference type="OrthoDB" id="26719at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055066">
        <property type="entry name" value="AASDHPPT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050559">
        <property type="entry name" value="P-Pant_transferase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215:SF10">
        <property type="entry name" value="L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215">
        <property type="entry name" value="PHOSPHOPANTETHEINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22624">
        <property type="entry name" value="AASDHPPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase N-terminal" evidence="4">
        <location>
            <begin position="35"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="3">
        <location>
            <begin position="128"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK99251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="292" mass="32648" checksum="96A0F92C2A751E5F" modified="2014-05-14" version="1">MSRAQSSPTVIQWVIDTRPLWPSALKTKDLTSAASRALSLLTEEEQSSVLRYYHVRDAKLALASALLKRYAISRFCHVPWFQAKTTRDARTKPVFVLPSGDEPLIFNVSHQAGLAVLLAVHDPPKGLAVGVDVVCPSERRDRDLSSLEQDGWASFVDIHADVFGAGEVSALKSMNPVPAVQERDRALRYFYALWCLREAYVKMTGDALLASWLKDLEMHNFAPPEDMEEAQEVRLRGKKVEGVDVRLMPLLEEYMISTAVRNGDNGERVELGEFQSLDMEEVLAFGEKASKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYV8</accession>
    <name>X0CYV8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_08984</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYV8"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000313">
        <property type="entry name" value="MFS quinate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF8">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="26"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK87647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="541" mass="59680" checksum="81FCA8CC2E3D081A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ88</accession>
    <name>X0CZ88_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_00229</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ88"/>
    <dbReference type="eggNOG" id="KOG2627">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024820_0_0_1"/>
    <dbReference type="OrthoDB" id="19679at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019148">
        <property type="entry name" value="Nuclear_protein_DGCR14_ESS-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12940">
        <property type="entry name" value="ES-2 PROTEIN - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12940:SF0">
        <property type="entry name" value="SPLICING FACTOR ESS-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09751">
        <property type="entry name" value="Es2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="92"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="271"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="351"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK99840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="450" mass="49721" checksum="4F7250A368BDC170" modified="2014-05-14" version="1">MDSSGSGTSNALVRKRTDTDLMPPPPQAKKIKRPKKVLDEDTYTEALSQIIARDFFPGLLQTEIQQEYLDALESKDSAWISSAGRRLQHVMTPGRRNAPLSSQANSFTAGDRTPSTYGGDTPASVTSNVPDPQPRLGANMSLTKFQDTYTSEDNESFYKLVDKQNQKKADKYAWLWRGNKLPSKQMIKQKEVEDRLSQTRSLIDDGFKKDLLAIKDKDDRPARPDSWNANPRNSLMFRPDGLEDGVLTVSQKAEESSKMAPKSIVYENTRMPQPRITPRPPSPTMSAVRDAIAGKPRKDDRDSSIVSGGETPRVNGYAFVDDEDDEDEPILPAPIINLGPGDAAPNPFRLQEQRDRESLHERMVERISQSKKESSRNGLTGRVDKTPVPKFPSSPRVNGGLTPAAQRLWSKIGTPGRGSSGSSFGNSKPMTPRGSLLRSVKRPGSTSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-07-24" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0J2</accession>
    <name>X0D0J2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0J2"/>
    <dbReference type="eggNOG" id="ENOG502RIX8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1578651_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL00291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="161" mass="18083" checksum="830D1B4D72216717" modified="2014-05-14" version="1">MTTPLYRLMPLSPRVQALQQDATTEVLTLFPVEKKEGLLTYGLPKSCGLLCEALLQDLEEDLKSWARGFGMVIKDLKMPEISPQAFRLEKGNTSTLLKGYTAIVVALGNTKYDVELVSRDKRSSQKETWEPTSALHLRETGLKAQGGHIRFLYIPLHLEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0D180</accession>
    <name>X0D180_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_08270</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D180"/>
    <dbReference type="eggNOG" id="ENOG502SHT0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012331_2_0_1"/>
    <dbReference type="OrthoDB" id="189997at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF1">
        <property type="entry name" value="PYRIMIDINE PATHWAY REGULATORY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="115"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK88442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="724" mass="81186" checksum="A845D3675CA7231A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3W6</accession>
    <name>X0D3W6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin carboxyl-terminal hydrolase 22/27/51</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3W6"/>
    <dbReference type="eggNOG" id="KOG1867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008279_11_2_1"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02660">
        <property type="entry name" value="Peptidase_C19D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000127">
        <property type="entry name" value="Ubiquitin C-terminal hydrolase Ubp8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF937">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="1">
        <location>
            <begin position="179"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="514" mass="58712" checksum="D3D92BA791BBF5D3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0D425</accession>
    <name>X0D425_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_00991</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the secreted LysM effector family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D425"/>
    <dbReference type="HOGENOM" id="CLU_070842_0_0_1"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045030">
        <property type="entry name" value="LYSM1-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932">
        <property type="entry name" value="LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932:SF31">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="131"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="232"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXL01152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="260" mass="28857" checksum="ACA80094FBE5BA70" modified="2014-05-14" version="1">MESCSTCATILSSTPAYTKEKLSLPQDRRVACCARIICGKCIHKNERFADYCPYCQVSTGPTSLPQGLREPPAYTSLPSSSSRTAHISGAPPPYSAASPTPNVDDEKAALAQDVIKEDAPDILHFLDHRHDSVSSLSLRYGVPTHALRRSNNITSDHLILGRRTVLIPGEYYKGGVSLSPRPIEGEDEELRKGKIRRFMTSCKVSDYDIAVLYLEQSSYDLENAVTAYLDDEKWEQENPASGKSKKADKYKNRGPFWRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4H6</accession>
    <name>X0D4H6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_01073</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4H6"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_1_2_1"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK98039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="56559" checksum="7DD83E59E0853484" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4X5</accession>
    <name>X0D4X5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4X5"/>
    <dbReference type="eggNOG" id="ENOG502SP4B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041569_0_0_1"/>
    <dbReference type="OrthoDB" id="3508416at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="53296" checksum="93731311378D8A6E" modified="2014-05-14" version="1">METPPTPTTRESSSSPDLDVTPPPYQLSSPFTRPSTISTGSELKNKSHMPFSQAAGESPSLHRDRGPLLQANLNAVIEETPAYRAPQFRTDPISMYMRNHEPCNFTPQKPMPFNPNVAGLATPANPIRQPAVPPPDHAASTRSLFPGALAPSPALWEGLRGHFSQLGINEHQSMASPITLPPARTPPAPIQEAQRPVLPPVLPSWLEDALKKGPYLQNQDDHCQKLSLAAHQQNARGFRPMAAITRPPSHTTREDEARESIFSDNYKGEHNTRNASALSLTPEQNCALWLTNLPPDVTHHELLGQIRNVGRIWCSVINEPDWQRHETAAAKVVFFTPGPAQLLLSKSLTQGLSVRGFPVRVTHNRVKYGEQAIMGPASRVLIITGKSTFVNPSCLTEFFEERFVFEVDEITELIVQGDASKGGRSVVEYRFGSFRCQAQMGKMALEKDRPQGFEKVEFGEDPCEVGDTLSAYGIAAERIQGKGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0D572</accession>
    <name>X0D572_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Wax synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_07316</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the wax synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D572"/>
    <dbReference type="eggNOG" id="ENOG502SAIV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021051_1_1_1"/>
    <dbReference type="OrthoDB" id="2796277at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF67">
        <property type="entry name" value="WAX SYNTHASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="8">
        <location>
            <begin position="349"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK89797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="539" mass="62244" checksum="764C620540A2C858" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0D736</accession>
    <name>X0D736_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription initiation factor TFIIF subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_07243</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF alpha subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D736"/>
    <dbReference type="eggNOG" id="KOG2393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76676at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005674">
        <property type="term" value="C:transcription factor TFIIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001096">
        <property type="term" value="F:TFIIF-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008851">
        <property type="entry name" value="TFIIF-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011">
        <property type="entry name" value="TFIIF-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="110"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="331"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="345"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="447"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="459"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="472"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="521"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="573"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="594"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK90462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="665" mass="73515" checksum="482D12EEA84EB61D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8B9</accession>
    <name>X0D8B9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Serine/threonine-protein kinase BUR1</fullName>
            <ecNumber evidence="4">2.7.11.22</ecNumber>
            <ecNumber evidence="3">2.7.11.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Serine/threonine-protein kinase bur1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_00198</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="4"/>
    <dbReference type="EC" id="2.7.11.23" evidence="3"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8B9"/>
    <dbReference type="eggNOG" id="KOG0600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_21_1"/>
    <dbReference type="OrthoDB" id="28397at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07866">
        <property type="entry name" value="STKc_BUR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000562">
        <property type="entry name" value="Serine/threonine-protein kinase bur1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000514">
        <property type="entry name" value="Serine/threonine-protein kinase BUR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF233">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="34"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="366"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="411"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="467"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="511"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00073250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK99798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="534" mass="60982" checksum="4B291D2F83C104F0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9K5</accession>
    <name>X0D9K5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prefoldin subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_00483</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9K5"/>
    <dbReference type="eggNOG" id="KOG4098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113004_1_0_1"/>
    <dbReference type="OrthoDB" id="29646at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23163">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000002">
        <property type="entry name" value="Prefoldin subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027235">
        <property type="entry name" value="PFD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13303">
        <property type="entry name" value="PREFOLDIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXL00224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="118" mass="13663" checksum="83E3E756C7DD2CDF" modified="2014-05-14" version="1">MSSAAQVPAKKQQDLQVTYSNYKNTLQQIAQRIGDIEQEAEEHKLVLETLEPLSEDRKCFRLINGVLVERTVKDVVPALKTNQEGLRKVLDDLVKQYKTKQDDLEKWKKKNNVQVVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBT5</accession>
    <name>X0DBT5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="19">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">FOQG_00897</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 19">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38567"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:38568"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="19"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0206">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090556">
        <property type="term" value="F:phosphatidylserine floppase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000026">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000047">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000010">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 18 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 17 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 19" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1066"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1105"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1148"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1182"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1213"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1256"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="22">
        <location>
            <begin position="235"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="21">
        <location>
            <begin position="329"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="23">
        <location>
            <begin position="1034"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="20">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="16">
        <location>
            <position position="616"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="616"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="616"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="617"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="710"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="751"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="774"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="807"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="888"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="889"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="890"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="981"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="987"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1008"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1011"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1012"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1012"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00051303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EXL01009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1364" mass="152956" checksum="D4F8627E60138071" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCK2</accession>
    <name>X0DCK2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Topoisomerase 1-associated factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_00819</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the timeless family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCK2"/>
    <dbReference type="eggNOG" id="KOG1974">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004390_0_0_1"/>
    <dbReference type="OrthoDB" id="310853at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031298">
        <property type="term" value="C:replication fork protection complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044998">
        <property type="entry name" value="Timeless"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006906">
        <property type="entry name" value="Timeless_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940:SF4">
        <property type="entry name" value="PROTEIN TIMELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940">
        <property type="entry name" value="TIMEOUT/TIMELESS-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04821">
        <property type="entry name" value="TIMELESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0236">DNA replication inhibitor</keyword>
    <keyword evidence="6" id="KW-0469">Meiosis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Timeless N-terminal" evidence="9">
        <location>
            <begin position="37"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="315"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="554"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="793"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="896"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1016"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="576"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="910"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="967"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="985"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1039"/>
            <end position="1056"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXL00850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1144" mass="131034" checksum="6A63124745FAEA5F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0DRG4</accession>
    <name>X0DRG4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cysteine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cysteinyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_02275</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DRG4"/>
    <dbReference type="eggNOG" id="KOG2007">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013528_3_1_1"/>
    <dbReference type="OrthoDB" id="438179at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.640">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF3">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA synthetases class I catalytic" evidence="12">
        <location>
            <begin position="57"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="321"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="763"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="763"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="821"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK96867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="839" mass="93423" checksum="DD78EBD9E18E1C8E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0B222</accession>
    <name>X0B222_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19449</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979815">
        <property type="protein sequence ID" value="EXK75786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B222"/>
    <dbReference type="HOGENOM" id="CLU_3335655_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="38" mass="4313" checksum="784D5FD75B25E395" modified="2014-05-14" version="1">MIHSWPGAWTQSYMLHSWPGTSQGASTNCLEHVETRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B264</accession>
    <name>X0B264_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979773">
        <property type="protein sequence ID" value="EXK75841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B264"/>
    <dbReference type="HOGENOM" id="CLU_110793_0_0_1"/>
    <dbReference type="OrthoDB" id="27975at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="231" mass="26158" checksum="D1F9BD1F5DCAF669" modified="2014-05-14" version="1">MAVSSEPFSQHLTMCWHQELALRATRFWNTLSTSEQDMRRHTVLMAACRHQDIFYLVIHQLCCLWSIDKAAVHDIFDSLTALHNVDSTFDTIQQILNNDDLSPCGLRWYASFPQPIREALTGSGGKTFATHLVSFMGHFATLWHPLLDQAGLEDQPISGSVLKHDLDCSSPILRYILFVASSLQIGIVAGPDATILDEKFEKDETDKYSIRGESVREVLASEHTRLLHHHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2Z8</accession>
    <name>X0B2Z8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658761">
        <property type="protein sequence ID" value="EXK76126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2Z8"/>
    <dbReference type="HOGENOM" id="CLU_3335653_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="38" mass="4616" checksum="4E9F845F77CABCCF" modified="2014-05-14" version="1">MEWMEMDARTIHFHAVDTWTVDVEWIASLIRAEIQDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0B388</accession>
    <name>X0B388_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658751">
        <property type="protein sequence ID" value="EXK76186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B388"/>
    <dbReference type="HOGENOM" id="CLU_000288_125_17_1"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="72"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="429" mass="48052" checksum="A577631101176908" modified="2014-05-14" version="1">MQTWLSLGLRKRTVSKGSWENSQRGNRRSVRAAEPRTHYLPFSRNKNFVGREGVIAELQKLLFSHLASQRAALVGLGGVGKTQIALQLAHLAKNGSQSHQHYSVIWMPALSMASFEQACTRMIQVFDIEHADNEDPKETFKDFLSSEEAGKWFLIIDNADNMETLYGTTQEPGGIADFIPDCEHGCVLFTTRSREVAVTVAQTNVVELPGMNKKDARALLQSSLIQKEQMQDTVLADKLLDELAYLPLAITQASAYMKINKVSIKEYLRLLQNTDQDMVELLSVGFRDGTHYDAAQGAVVTTWIVSFKQIRALHEEAATLLSFAACLEPKAIPRALLPRLRSEQSMTRAIGTLCGYSFLSQREDGDMFDMHSLVHLATRRWNEDEDREEGIQQLALARIAEAFPTDDWENLTGAKMHVSWDTGLADACM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B493</accession>
    <name>X0B493_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658661">
        <property type="protein sequence ID" value="EXK76950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B493"/>
    <dbReference type="HOGENOM" id="CLU_054595_0_0_1"/>
    <dbReference type="OrthoDB" id="5021918at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="421" mass="46538" checksum="AF1041373921715F" modified="2014-05-14" version="1">MAPPDIPPEYVYYVKAGKKHHDLFTTIYAGENYCGRCGLANPFQSQRRARSRTPALPGPYDEVVEVDDSPPHPVSPASQLMRDKPKPVSSAATGYAQLLPNAVSVPNGVTANTRARQHPFKPSSGPPHPQFMAIASEASQAIQNTKSSTRKPTRQRTGYQWVHISLLLMSLETRYFNGLAVEVPETVLPLKDTVIKFSSADLLTWPSFTHTLFEHLHPLPSTVDPTNQELWKLSYASSFSGKKIVTVPNTDKFTTPSSMLTSGHFSNNQAGQLKVLVVLTSTDVGDKQEPITPLRTDEYSTPAKDGKKRKVKWEDSSPAPGLKKRIKQERQINQGNGTKNREQVKQEKAVPASTYLNLAYEDRNDILDNIVVKGDVVDLSESEDAVTDLMLDSVSDGEGDERDADQEDEVDCSSETSLFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0B564</accession>
    <name>X0B564_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AC transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_18371</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658669">
        <property type="protein sequence ID" value="EXK76896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B564"/>
    <dbReference type="HOGENOM" id="CLU_454951_0_0_1"/>
    <dbReference type="OrthoDB" id="5062167at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="263"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK76896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="600" mass="69363" checksum="AB6B46C796DB165C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5C2</accession>
    <name>X0B5C2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658624">
        <property type="protein sequence ID" value="EXK77315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5C2"/>
    <dbReference type="HOGENOM" id="CLU_1069950_0_0_1"/>
    <dbReference type="OrthoDB" id="5028450at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935533" evidence="1">
        <location>
            <begin position="17"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="240" mass="26513" checksum="124CF6E8E1A0AD18" modified="2014-05-14" version="1">MHSFKIILISLAPILAMPATSPRDINSDEPFDFGQGFLVPANLEGTLAPELGNITTEFDLDTRAPKETKVFFGKTQVDYGCDASIKEPLGEAIHSICGNGDCDKSVVYTRKVVHMAGGNRKKDAWLRIAVRGEYYGRHTRGYMASAVQQSVNPKTAVPATRYYLPTNPNFQAQKRKMSKFSNYINMRKNFGDTIYVEIDVTLQTSNSHRFIPNVLKEVAGALGGIGGSFFRYIVTAMIGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5J7</accession>
    <name>X0B5J7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutathione S-transferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_18245</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658650">
        <property type="protein sequence ID" value="EXK77036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5J7"/>
    <dbReference type="HOGENOM" id="CLU_011226_15_5_1"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03046">
        <property type="entry name" value="GST_N_GTT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF9">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01150">
        <property type="entry name" value="Main.1:_Beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="5"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="94"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK77036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="25035" checksum="8793651A70AA42B3" modified="2014-05-14" version="1">MIITQPDITLYFLNGSRAIRIAWLLEELGLSYKLVASSRGSNGQAPPEFKARIPTRLGNSPTIQDGDLVIQESGAIVEYLCEKYDAVSRLIPHEPRERAKVKQWIGASEGTFLLHALSILYTRMGMPKEAAQYVPELEAKFAPNVCGALEWLEAELKSGPSQGQFLVGTDLTAADIMMGFSIEIIFTMKVGTERQKWPMTNQWLADMMEREAYKKAVEKTGYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-09-13" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0B785</accession>
    <name>X0B785_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658552">
        <property type="protein sequence ID" value="EXK78010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B785"/>
    <dbReference type="HOGENOM" id="CLU_059037_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="45553" checksum="6175C883D262666C" modified="2014-05-14" version="1">MVESVRLRVLGAMESLLEGLLTEISLLVFNLLETKDLKNVALVNHRFRSFLEPSLFNRLLIDEHGVQELLENPKHKDVTYYTHTLTIRSTTYNLFAPGSILADLATKCKSGGFYQQLTPTVEGDKDKIWKSRCTLTDMSEPEARTAEILPAIRTLHISVEVKEKPGDLASVMGKFPNLTKLTINANSLQFPPEEVWPSLEQLIFDQIPSMEEKVALDQNHLKSWIEEHKKLRSIFFAELFEVYDISQDGSFSQELHQVLSRVSTPEVVDNIMTQASTELETYERLSERLRCIHPHLDRILDKTIAKKAKAEIFRFCSQRSLEFAKGRREALFPYGPDVTLVYRPMPVLECALQGAKDEIRNCSERASGFGDEGEFFQLLQDVVGGRVILRIKLLSDNISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8P0</accession>
    <name>X0B8P0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979366">
        <property type="protein sequence ID" value="EXK78136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8P0"/>
    <dbReference type="HOGENOM" id="CLU_150800_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="143" mass="16095" checksum="97F1519786A39010" modified="2014-05-14" version="1">MYWPPSTSKLLVSIHIHAIFTNVSWSVVDLNPDKSNGPIDEKIFYPKSKPILQIATTEDELFSVVFEDSKSEFCLFFDLRLFDEPFRAGLGHISEMFVEGQMDEAVGPSDSSSAKPTHGQSNKLSCSFSAFGTERIDYRGDYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9J2</accession>
    <name>X0B9J2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658501">
        <property type="protein sequence ID" value="EXK78805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9J2"/>
    <dbReference type="HOGENOM" id="CLU_054590_2_3_1"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF105">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G08790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="146"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="289" mass="31842" checksum="D56D55364F36471A" modified="2014-05-14" version="1">MSCPQCFSGHINPGTPTGRWDTVHGLRTYIAEPPAGKKPTAIIVIIPDAFGVDFVNNQILADHYASAADYLVYLPDFMDGNAAPVRTMINMAHLWHENESWLIKPYYFVAVLLDFVPFLYRNRLSVSWPRVTGFLKEVQQHKDAALPVGIAGFCWGGLHTVRLTHDTAETKTGSGRPLADAFFTAHPSNLDIAQDMGNVARNLSIAIGDDDGVMGMKQVRQAESILASKDVDTSVVIYPGAKHGFSIRASRAKPDSQETRQAQEAEEQAIAWFKRQFGTIKQNADSLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAU3</accession>
    <name>X0BAU3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_16475</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH658495">
        <property type="protein sequence ID" value="EXK78891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAU3"/>
    <dbReference type="eggNOG" id="ENOG502T5YR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039414_0_0_1"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="7">
        <location>
            <begin position="301"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="480"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK78891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="555" mass="62484" checksum="A35605A92C092AD1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB54</accession>
    <name>X0BB54_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658488">
        <property type="protein sequence ID" value="EXK79011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_236151_0_0_1"/>
    <dbReference type="OrthoDB" id="5077295at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="586"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1840"/>
            <end position="1866"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="300"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="373"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="536"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="629"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="805"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="913"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1261"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1368"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1544"/>
            <end position="1587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1878" mass="213558" checksum="07F6B136AD97B19D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB86</accession>
    <name>X0BB86_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_15947</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JH658471">
        <property type="protein sequence ID" value="EXK79430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB86"/>
    <dbReference type="eggNOG" id="ENOG502RY3D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_1_3_1"/>
    <dbReference type="OrthoDB" id="4849160at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF36">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935607" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="16">
        <location>
            <begin position="22"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="17">
        <location>
            <begin position="22"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK79430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="257" mass="27950" checksum="4F21F653B460EBFE" modified="2014-05-14" version="1">MLPTTVLLATLSALFTSEVSAHGHVSEVLINDKSYYGHDPTKLPYGPQPESITWTNGAKDNGFVTSTASALASPDIICHLNATNGHLTADATAGTTITVRWSDWPEAHWGPVLDYMARCPNDDCTKVDKTKLKFFKIDEMGQLTRGTIPGKPGYWANNKLRDEDFSWNITIPAKLAPGSYVLRHEIIALHAGGAEGTTQMYPQCINLVIKGDGTAQPDGVFATDLYSSTDPGLLHNVFVDEWSNAEYIIPGPSVVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBF4</accession>
    <name>X0BBF4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_19094</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979589">
        <property type="protein sequence ID" value="EXK76148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBF4"/>
    <dbReference type="HOGENOM" id="CLU_002865_7_2_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="510"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="554"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="17"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK76148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="575" mass="62781" checksum="2A00282347B33BF1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE88</accession>
    <name>X0BE88_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658443">
        <property type="protein sequence ID" value="EXK80470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE88"/>
    <dbReference type="HOGENOM" id="CLU_030115_1_0_1"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="358" mass="41492" checksum="B547EFAB71417FB4" modified="2014-05-14" version="1">MRYIKNKTKIPLPDIHAYGRNEKLVRDSSTTQAFLILDFVSGQPLDLQALRDDTLSRRKHFYAQLIEVMTQLRTLEFTKSGSLMPGHEAVPVVDNVLSIPLNEFQVDSNQARSLPMAHSAREFALNQLNLMREEYRLPRSELSRETVEMEIFALNHLKQLTQELADAPNCFVLSHSDLRPTNIIVDDDLNITSILDWEWTHTVPRQFFMPPSWITLHNLVKSAELGHSESFLEFREVLEEMAKSSSLYRPLANEWGPDLPNKLMLPLAEILRGHSNLLGIYYKFIFPWCFKNTREEVVAEFLRGSKDHASEVNKRIADSHQYTQYLKDSDLYIPDDGVRKEQEWLEKARLLNEKLGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFA7</accession>
    <name>X0BFA7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA/RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658442">
        <property type="protein sequence ID" value="EXK80496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFA7"/>
    <dbReference type="HOGENOM" id="CLU_010014_4_2_1"/>
    <dbReference type="OrthoDB" id="2017974at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005697">
        <property type="term" value="C:telomerase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000202">
        <property type="entry name" value="Unplaced genomic scaffold supercont1.7, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF0">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN EST1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA-binding" evidence="2">
        <location>
            <begin position="270"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="610" mass="69802" checksum="D3D52C6256C940DD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFL4</accession>
    <name>X0BFL4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658440">
        <property type="protein sequence ID" value="EXK80601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFL4"/>
    <dbReference type="HOGENOM" id="CLU_3406427_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="30" mass="3464" checksum="4CAB58956F63922D" modified="2014-05-14" version="1">MTGDSPYWVKTEDWHTAGEPFRIFQNVPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGP5</accession>
    <name>X0BGP5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979379">
        <property type="protein sequence ID" value="EXK77644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGP5"/>
    <dbReference type="HOGENOM" id="CLU_3050368_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="54" mass="5808" checksum="3FA7BE100BED4ED8" modified="2014-05-14" version="1">MLLLDKRAQAGRCPGGRVKYWRSMMAMTLAASPTASAVANDDILTVREAVSKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGQ8</accession>
    <name>X0BGQ8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658551">
        <property type="protein sequence ID" value="EXK78033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGQ8"/>
    <dbReference type="HOGENOM" id="CLU_2084952_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="117" mass="12951" checksum="111E3DA26C010BF4" modified="2014-05-14" version="1">MWMFAIRALRMRRQQQHPIFNEFIGNGSYDALNKFTVTVAGVNGFVAILIGETLPNNTDLPDDKALGSATTRRIVGTSHYVLVTVTVIAAAFVAWRESGLTQKLCKGQHLRSLFVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH57</accession>
    <name>X0BH57_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658571">
        <property type="protein sequence ID" value="EXK77789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH57"/>
    <dbReference type="HOGENOM" id="CLU_057752_5_3_1"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="79"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="290" mass="33061" checksum="910BE3CFD1BC91E4" modified="2014-05-14" version="1">MDYPRGPQKLVETVQYLIGQGAFAFGSPAAVTLEFSDPRDTDIPGAQSPVESLTGRQPRKLTMLDFSWLRNSLKDDSYADLTLISRTKQYSAHRVVVCSQSPVIIKKFQSQFQNTKQDPSCDACGATPRYCFDISQDDPQAVDCLVQYFYRQDYQSSSSNPAAEDTRSDEAEGAISSSVLKQSSIDDSYPIFHVRVYALAEFYNVPALKELALEKFNRVIQDNSELDRFLDGVEEAYESTIQEDRGLRDTIVNFFYKHSDLLKEERVQDIIQDTNSLAYDLLMHWEDVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHF9</accession>
    <name>X0BHF9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979335">
        <property type="protein sequence ID" value="EXK81246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHF9"/>
    <dbReference type="HOGENOM" id="CLU_1326438_0_0_1"/>
    <dbReference type="OrthoDB" id="5426789at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK81246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="207" mass="24159" checksum="8DF57AA06FFC3231" modified="2014-05-14" version="1">MISYSSGFSPVISYSIDSEQQLLKSNKQFLEPMDTKDWKIQHCRAAAHTIVTSLIENIDDDRKMIQRLGSWLYLHPNVHKRWPALPTRNGILRPGYFLIGRDVVFALLLWERLVFERRWQLDEEFRDQVWLLHERKYTGRGLNDSPNRNVPATRGKPEKGDGLDGLLEAFDEVYRILDHTSPERSVVDDLVPVTLQASGCDTWQLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIK6</accession>
    <name>X0BIK6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_17025</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979364">
        <property type="protein sequence ID" value="EXK78294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIK6"/>
    <dbReference type="eggNOG" id="KOG0659">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017514_0_0_1"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF1">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE EPSILON SUBUNIT HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="795"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="822"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="162"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK78294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="846" mass="95192" checksum="29D2802A531F6130" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIS9</accession>
    <name>X0BIS9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_16951</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658525">
        <property type="protein sequence ID" value="EXK78369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIS9"/>
    <dbReference type="OrthoDB" id="3362851at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="46"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="132"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK78369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="692" mass="78329" checksum="2C02732A2507E6AA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIV4</accession>
    <name>X0BIV4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13828</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658422">
        <property type="protein sequence ID" value="EXK81756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIV4"/>
    <dbReference type="HOGENOM" id="CLU_007383_8_0_1"/>
    <dbReference type="OrthoDB" id="300709at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF14">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="3"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="359" mass="40211" checksum="C4F3D91CA5E5A8F8" modified="2014-05-14" version="1">MAHRIFVIGATGAQGLPVCRGLTKDGAYSLRVLTRDVNSQRAKQLAELGDVEFIEGSFANEDNLRKGYEGCWGAFVNIDGFNTGEKTETYWTIRAYELAIESGIKFFVFGNLDYGYKKSGYDPKFRCGHYDGKGRMAEWMLSQRKAHSMGTAIFTTGPYIEMAVSAQTVMTPRIVDGVVTWAVPLADGAIPHVALDDCDHYVRWLFDNPERSDGLDLEVAIDHIAYHDLAQAFQKVTGKPAQFIDIPLATYFDHLPLKGTVPAGYNADPNDPATMTIVQNFTGFWNMWRNSGGNKGVIKRDYKLLDEIHPNRIRTAEDFFRREEEKRKAQGLPSIFETIESGNLGMILKLSEDGRKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJS1</accession>
    <name>X0BJS1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_16233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658481">
        <property type="protein sequence ID" value="EXK79128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJS1"/>
    <dbReference type="HOGENOM" id="CLU_000960_25_1_1"/>
    <dbReference type="OrthoDB" id="2587356at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF195">
        <property type="entry name" value="PEP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="531" mass="56791" checksum="0BD4E0E664471640" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK51</accession>
    <name>X0BK51_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_16138</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI979350">
        <property type="protein sequence ID" value="EXK79247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979350">
        <property type="protein sequence ID" value="EXK79248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK51"/>
    <dbReference type="eggNOG" id="ENOG502QW74">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041456_5_1_1"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000020">
        <property type="entry name" value="Unplaced genomic scaffold supercont2.4, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF247">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="361"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="492" mass="54492" checksum="4F9F970BEED44637" modified="2014-05-14" version="1">MAKTKSKKRKQAQAQAQSENSRKVAKTTSPSIPTPPPDGTTTHFEPKNLHTVVSEEELEITIDTLNSLAQYPGLIKSKLCKDLRVAVYDFRQACTTGVNNAAGANLTAQVTAALADRKYTEARILLAEMKIRGEQPKLGALCRWVRDLDVISGLSTIPDQQGLVKRSEREETLIKVIDAVLRVCGHEDRNPNAIIQPSSIALQEIWDLRPDTPTEQVYASVLDGSLVASAPESLKKNIRIIETTPGPERKPPNHHDAILYASTPEAVPLSATPPPTTHRPHPVVQGLSVATNVLYPEECKAIIAAGEYVNFVPDAPLREDGDISILAHNFYWVVDNTFHDTLWSRIQPFVPVSMNGRLARGINRRFRVYRYVPGAEYRAHIDGAWPPSGITKEDKYVYDDSPAEKKQSSLFTFLIYLNQDFEGGETTYFLPAAREGILNAYPVRPVMGGAAIFPHGEINATLHEGTGVRKGAKYVIRTEIEYDVEPTEEVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK56</accession>
    <name>X0BK56_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658499">
        <property type="protein sequence ID" value="EXK78844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK56"/>
    <dbReference type="HOGENOM" id="CLU_2133654_0_0_1"/>
    <dbReference type="OrthoDB" id="5130748at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="113" mass="12263" checksum="A7DCA88698668FD4" modified="2014-05-14" version="1">MEGVMDTMLKDSTGNTFDAPAQPLVNFVVSEYVSIGNICGLTSNNVVPLPPFQTILTTHRTLKSCADSPTCNPPFYVLATYLGKSTMLEAYYVCFISSSLSSWFASMNCTVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKB3</accession>
    <name>X0BKB3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658494">
        <property type="protein sequence ID" value="EXK78904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKB3"/>
    <dbReference type="HOGENOM" id="CLU_064116_0_0_1"/>
    <dbReference type="OrthoDB" id="5232980at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="271" mass="30078" checksum="30AD3D8943C99190" modified="2014-05-14" version="1">MLRQKAHHWADKHDFQTLTTALGPLLNPSDPQCLNGTKSSAARARYIHGASILFAWFITYGDLVTVLSQPPPQRFHLSGQSFYQLYEEPIIKGKMDNQAVKKIVIAHPTVGAAVDFTYEMWPHDEPSLWITTFGIPDIKVYWRQVKTTKPNHHSYDSGVGCEETGEALSHQLNNEKGAQLPPKVTQVATSIAPKKSPGLTQTTKKKKKKMNSSEKAGTVKKRDEEDIALDPLKGKPPVGLAAVAHSTGVIGQNKSAESEKRKREKKRSGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLP1</accession>
    <name>X0BLP1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD repeat-containing protein C3H5.08c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_12864</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLP1"/>
    <dbReference type="HOGENOM" id="CLU_004759_4_1_1"/>
    <dbReference type="OrthoDB" id="1932312at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040324">
        <property type="entry name" value="WDR44/Dgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221">
        <property type="entry name" value="WD REPEAT DOMAIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="66"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="136"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="176"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK82741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="476" mass="52401" checksum="FB9ABFD7A8397375" modified="2014-05-14" version="1">MTETHSQGSHVIAQAKTPGYIQIKHRNSRNSQFRNLFLAQELIGGTQPVHSLARSATQVAIGGKILNGGEATIWAAEFSPSGRYLAVAGKDPSIRVFKVMSTGEERMAQEGEGNQAGLEKKRFSAPVFLSKPIREFAGHTGEVLSLSWSKNDFMLSCSTDKSARLWHPSQPTCLRVFQHDKTVPSIAFHPTDDRFFLSGSFDAILRLWSIESTSVAYSSSMTDVITAVAFSPDGKTAIAGSFTGTCIFLNTVGLKEERRTCTWPPYAKVEIGVKITGIQTVLASGSNDANPQVKVMITTNDSRIRIYNLTDQTLTAKLEGSLNLSSQIRARFNDDGSYVVCGSEEDRVHIWHLGLGKPQLKHEQPHESFRTHSEVVTNALIAPTASREIISASKDQIYDLCNAPPVALCGLQENTAHGTNTSCLMFGETELTTAQLQEHREYLERSRHPDGNIIVTTDTMGKVKVFRQDCAFSKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPJ0</accession>
    <name>X0BPJ0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_15101</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658446">
        <property type="protein sequence ID" value="EXK80394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPJ0"/>
    <dbReference type="eggNOG" id="ENOG502QURZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010170_0_0_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF9">
        <property type="entry name" value="TAH-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="615"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="619"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK80394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="720" mass="80376" checksum="4A994BFCE73DE1AF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRI4</accession>
    <name>X0BRI4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_11030</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRI4"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_12_0_1"/>
    <dbReference type="OrthoDB" id="10029326at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="546"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="624"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="662"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="713"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="741"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="8"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="291"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK84785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="780" mass="86926" checksum="664E2985FF0A7CE8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRT6</accession>
    <name>X0BRT6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRT6"/>
    <dbReference type="eggNOG" id="ENOG502RF2F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058261_0_0_1"/>
    <dbReference type="OrthoDB" id="3057599at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="317" mass="35549" checksum="E83B413FFADED504" modified="2014-05-14" version="1">MDLIFQPFRLTSMLLGTLQRAIAFSLLPALAYGLFHQTFLAADVYTRTMIPIQNMASPLSEEDHHRIFGPGHETLKGATAANSMLLDYLTPNVIGCIAQAIELGHPKIILGAVLATLSNSVYLVVARIFDFSEAENGHYSVHIHAKSFYASSGIMSIYCLSNWVLRPHGSIRTCRPVYGLVDFVSLVYRSDILLCPEFWLQDSADTEEDMNAQVTLANRLYQYGIYHGIDGRRHVGIGVEYAPPARLLDDENTLCLDWSVNLARAAISSGIYSNASLVSAENFITNEPQRRSSLRRVRTNQYRSWRRRAKEIMSLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXF1</accession>
    <name>X0BXF1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658400">
        <property type="protein sequence ID" value="EXK83613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXF1"/>
    <dbReference type="HOGENOM" id="CLU_2038141_0_0_1"/>
    <dbReference type="OrthoDB" id="5104994at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="128" mass="14793" checksum="CEAA7F1E1EEA1CFA" modified="2014-05-14" version="1">MSQSTGDHPRRSLPFLPPELTLRIIEESEEASEHTTVIYPRSDRKEDGTFTRGKFEVLPMQHRCVAGVIQASDTPALPFDPREDQTSYDTRQNLHLEGSMGHPQKARKWSCNRNRRKQMEQMAKRLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-09-13" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXJ9</accession>
    <name>X0BXJ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658405">
        <property type="protein sequence ID" value="EXK83204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXJ9"/>
    <dbReference type="HOGENOM" id="CLU_1740598_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="17273" checksum="422796EEB58BED07" modified="2014-05-14" version="1">MLQPGLEAVENSLHTDCQHHSTFSSFKQAVDDRCYVCAKLWDSVADASIKGWSNEPCTWVPFDCGLGRRTWAPRWFGAIYWHMRYLEFGMEPNVKLKYKGNVFCFLPCEDEKSSMLEVLSIGFQTSTSSEKVQQLAYEWYEACSDSHKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ53</accession>
    <name>X0BZ53_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19419</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979794">
        <property type="protein sequence ID" value="EXK75817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ53"/>
    <dbReference type="HOGENOM" id="CLU_149467_0_0_1"/>
    <dbReference type="OrthoDB" id="5099858at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="151" mass="17875" checksum="782433344E10275F" modified="2014-05-14" version="1">MTSRYQTCECKSTSPPVKDFPHLALLVNNNEEETISELPMCPKQVDEICNKSPKRVFLHYTTINTEAVSAESAPETIRVIGYQEEWERKVEIWFENNNYEPVEHHTLDSEFFPNCYQGLDRFASYAYQLDYSRHAWYMKKELEHRSATLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZ74</accession>
    <name>X0BZ74_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sialidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZ74"/>
    <dbReference type="eggNOG" id="ENOG502R6VZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020422_0_0_1"/>
    <dbReference type="OrthoDB" id="5300765at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="567" mass="61572" checksum="BE41C79C58AD7AC6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZC1</accession>
    <name>X0BZC1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979327">
        <property type="protein sequence ID" value="EXK83864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZC1"/>
    <dbReference type="eggNOG" id="ENOG502QU9T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029940_1_0_1"/>
    <dbReference type="OrthoDB" id="3162524at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="29"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="311" mass="36019" checksum="02040CD33572B61B" modified="2014-05-14" version="1">MPKRILCSYGVDVDAVAGWLGSYGGEDSPSDISRGLFAGTHGTRRMLKLFDKYNIKATWFIPGHSLETFPEECAMVRDAGHEIGLHGYSHENPSDMTLEQQRDVLEKTHKMLTEFCGKPPRGSVAPWWETSKEGVDLMLSYGIEYDHSMSHDDCHMYWLRTNDSWTKIDYKKKAETWMKPLVKGQDTGLVEIPANWYLDELTLPPMMFIKDAPNSHGWVNSRDVEDLWRDHFDYFYREYADDPDEICVFPLTVHPDVSGRPHALLMHERLIEYINKHEGVEWVTMEQMCDEFKKKNKPPKGAVMPKAQEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZN1</accession>
    <name>X0BZN1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZN1"/>
    <dbReference type="eggNOG" id="ENOG502SJT5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047586_0_0_1"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="86"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="340" mass="36876" checksum="81E261E3642FF424" modified="2014-05-14" version="1">MTKHLGLSPRIIRKALIMSQDLVLPRPGASYKPQPPVAGPTEAAFVETFGALLPAAQFLQTPRGKAAYYELTPSSSKDDTTEIDKVLFIHGVQTPALGMLPLARDLEKTFPAAHMVLIDLWGHGLSDTPVVPHEASLFHQLIDDLLDHLSWPSAHLVGFSFGGATTVSYVASRPSRVKSFTLVAPAGLLQLSMFTPDEQACLQGDDEDAAKKCVLNILEGGDLVVPADWKQRVAKGEVVAEAVREWQMREHLGHTASVVAIFRDGGVMGSHAHFDEAAKTGIPSLAVLGELDSLCSKDQLDEHGFENVFVVPKAVHSVVRDQAEDVANLIGDFWKKIEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZP1</accession>
    <name>X0BZP1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK83989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZP1"/>
    <dbReference type="eggNOG" id="ENOG502S90D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096188_0_1_1"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02231">
        <property type="entry name" value="cupin_BLL6423-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047142">
        <property type="entry name" value="OryJ/VirC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156:SF3">
        <property type="entry name" value="CUPIN 2 CONSERVED BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156">
        <property type="entry name" value="SLR2101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="97"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="190" mass="21010" checksum="4FACF86B32347C5A" modified="2014-05-14" version="1">MSSNSSPPKPLPSIHRFITTHDSSGKSCYSKDLDEPLNFWKVSAGDGNSADFELGYITEGLPIPLANDKDLSTFKEAYANKEKSGLVKHGGTILRYCDIPPGSKSQMHRTVSLDYGILINGELECLLDSGEIRTIHPGDVVIQRGTNHQWFNRTEEWARIVFILFHATPVEINGRALGEDQGGMELPDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0T2</accession>
    <name>X0C0T2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0T2"/>
    <dbReference type="HOGENOM" id="CLU_026308_0_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF1">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE EPSILON SUBUNIT HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="191"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="674" mass="76372" checksum="A724B155AD0139E9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0Y8</accession>
    <name>X0C0Y8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Delta(24)-sterol reductase</fullName>
            <ecNumber evidence="2">1.3.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08683</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.3.1.72" evidence="2"/>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0Y8"/>
    <dbReference type="eggNOG" id="KOG1262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025883_0_0_1"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000246">
        <property type="term" value="F:Delta24(24-1) sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050614">
        <property type="term" value="F:Delta24-sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000031">
        <property type="entry name" value="FAD binding domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040165">
        <property type="entry name" value="Diminuto-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801">
        <property type="entry name" value="24-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801:SF10">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14300)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="11"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK87781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="541" mass="60878" checksum="545955E8FB643BE4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C249</accession>
    <name>X0C249_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C249"/>
    <dbReference type="eggNOG" id="KOG3824">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053737_0_0_1"/>
    <dbReference type="OrthoDB" id="439046at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="entry name" value="Fido-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504:SF38">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="Fic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="3">
        <location>
            <begin position="162"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="259"/>
            <end position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="335" mass="38428" checksum="95C785D80679AEFA" modified="2014-05-14" version="1">MELNNLTLKPDCPNHHPSFAFDDVYRTYKDDQNPEALFGKALRYLSSLRVNHTSEQQEIIRGEIMQSLFHTIYGSNRIEQAGLGCDVTRYLCYKTLHEPDSILEVNEDDSAFDEKVSDLYAADPTLRGKSKSYIVRGRREVIQHVRAFKYIMDRFWVHGDDLMEDVIKKTHEILCKGVPIIDPGAEYLDVPYEKYAGQYRDVPVGAGNTMFVMPQYVPAKMAEMCANLKKHIGKNESLDPFSLAAKYSLRFVEIHPFQDGNGRMCRIILNAILFRYVGIFIPIGVTEEEINEYINIKKRASRDMEGHGEYATFVLKKSVRSIQKLKQKVNGKKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2T0</accession>
    <name>X0C2T0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial phosphate carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_11021</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2T0"/>
    <dbReference type="eggNOG" id="KOG0767">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039456_1_0_1"/>
    <dbReference type="OrthoDB" id="427452at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF15">
        <property type="entry name" value="MIR1-PHOSPHATE TRANSPORTER OF THE MITOCHONDRIAL CARRIER (MCF) FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="14"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="113"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK85089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="33449" checksum="003C796CE158AE0F" modified="2014-05-14" version="1">MATKQSEVPNFTISDYVKFFGAGALAATSTHGAVTPIDVVKTRIQVDDALKGYNMLSAGRSIVAKEGASALLTGFGPTAVGYLVQGGAKFAGYEFFKKKYITMLGGPEKAVDHRTGVYLTASASAEFFADILLCPLEATRIRLVSQRGYADGLLSGFTRMAREEGFKGFYSGFVPLLFKQIPFAVGQFSVHEAVNEVIYRAMGPERKQKLTQLESTGVELTSGITAGAAAAILSHPADTLLSAINKGAGDKSQGATSRMFQLAKEFGPKRLLLTGLGPRIVMTCGLVGAQFVVYAQCKALTGAPPSIEIHKEESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2T8</accession>
    <name>X0C2T8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_18184</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658642">
        <property type="protein sequence ID" value="EXK77102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2T8"/>
    <dbReference type="HOGENOM" id="CLU_028200_0_4_1"/>
    <dbReference type="OrthoDB" id="3648173at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="34"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK77102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="305" mass="34067" checksum="46B6DBAA6D4E1F6B" modified="2014-05-14" version="1">MDSRSMPADSSSRSVQIRAILITFSILSAISVTLRIYVRYKVLRSLGWDDRVMAAAQLLAIGSAVAIGLENNYGLGHHTWEQSKENYVTYMKAFYASVIVYNVAMCLVKIGILLQYRRVFAIPILQAFTFYGLVIMATWTITIALLNALICVPVAKFWNSTMPGHCIDPLTVWYVMAGFNLVTDITVICMPLPVIGSLNLPRRQKIMLLAIFSIGFLTCAISIYRIHTLKTAASTKDPNWDNVDAAIWSYLEVTLAIITSCLPTLRPLFSKLMPKLFASSFGRSNRPSDYGYTPTHSSQNLRSMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3A9</accession>
    <name>X0C3A9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3A9"/>
    <dbReference type="eggNOG" id="ENOG502SPRZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_359817_0_0_1"/>
    <dbReference type="OrthoDB" id="5307331at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="666"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="761"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="794" mass="88722" checksum="23DB7AEDC83CD456" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0C419</accession>
    <name>X0C419_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_07857</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000709_0_0_1"/>
    <dbReference type="OrthoDB" id="162894at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901992">
        <property type="term" value="P:positive regulation of mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05611">
        <property type="entry name" value="STKc_Rim15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000340">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000664">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000139">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:001008">
        <property type="entry name" value="Serine/threonine-protein kinase cek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="15">
        <location>
            <begin position="36"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="725"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="16">
        <location>
            <begin position="1152"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="1521"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="275"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="457"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="523"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="578"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="980"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1191"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1285"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1402"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1689"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1859"/>
            <end position="1917"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="469"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="532"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="585"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="612"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="626"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1285"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1312"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1370"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1402"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1435"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1448"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1690"/>
            <end position="1703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1751"/>
            <end position="1775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1778"/>
            <end position="1787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK89145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1917" mass="209906" checksum="C0E274BC2CD2A5C8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C455</accession>
    <name>X0C455_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">6-phosphogluconolactonase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658593">
        <property type="protein sequence ID" value="EXK77547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C455"/>
    <dbReference type="HOGENOM" id="CLU_038716_0_1_1"/>
    <dbReference type="OrthoDB" id="10484789at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936165" description="6-phosphogluconolactonase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32253" checksum="1FD0307432F71F6B" modified="2014-05-14" version="1">MLLLAFNVAVFFAKLAFAKKQPDNPTTSPTTPAHILVGFPKHISVANKVQGFPFSIDKEVTGIPSWMTVSYPNLLYAVDESSNALTLFELNLTLWWFLTNDDAFQIVNIIHISPHGCDPRHGIFYPQGAFRATHYILVCEISNKVLVYTVSYRENYLDFTQIQSTSTFGPRLPPANSSSAASGAIVLAADNRHLYVSNRQTGNSTDSVSHFQIDQLNSTSLSLKFVGSASTYGVSPRMMSFSHDDQYLLIANQAGGFGPVALERRLDGTLRAENPISVLGAPDFTPQFVQQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C641</accession>
    <name>X0C641_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gag1-like clamp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C641"/>
    <dbReference type="eggNOG" id="ENOG502SRCS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5422958at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053274">
        <property type="entry name" value="Fluconazole_resistance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025124">
        <property type="entry name" value="Gag1-like_clamp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28065:SF1">
        <property type="entry name" value="DUF4050 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28065">
        <property type="entry name" value="FREQUENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13259">
        <property type="entry name" value="clamp_Gag1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gag1-like clamp" evidence="2">
        <location>
            <begin position="319"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="586" mass="63619" checksum="961B98C6AA380BA9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7H3</accession>
    <name>X0C7H3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nitrate/nitrite transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_09568</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7H3"/>
    <dbReference type="eggNOG" id="ENOG502QPIC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024204_1_1_1"/>
    <dbReference type="OrthoDB" id="434240at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015113">
        <property type="term" value="F:nitrite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004737">
        <property type="entry name" value="NO3_transporter_NarK/NarU-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00886">
        <property type="entry name" value="2A0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="453"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="36"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="243"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK86749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="513" mass="55334" checksum="BDEA9E89CBA1AAAB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C855</accession>
    <name>X0C855_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane protein 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06825</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C855"/>
    <dbReference type="eggNOG" id="KOG4491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036918_1_0_1"/>
    <dbReference type="OrthoDB" id="30881at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002794">
        <property type="entry name" value="DUF92_TMEM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK90600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="40437" checksum="017517E4AEE22EB7" modified="2014-05-14" version="1">MRLLYALPATCALIYRAKSRNSLTPAGIFAATLTAAAHAYHPWNLPFALLCVFFLAGTRVTHIKEGIKANYTLRSKGTSGGEGPRTHVQVLANSLMASVLSVLHANQLRKREAAFADPNIPDPTGSLCFSWGGDLLVVGIIANYAAVAADTFSSELGILSSGQPRLITSPTLRKVPRGINGGVTLLGLGAGLLGSMIIVTASMIFLPSCSEESSRTPAGGAPWTMLERRKFMGFMVIWGALGSVLDSFLGGLFQRSVRDVRSGKIVEGEGGNRVLVAESAMDAAAHSNVKTEAMQSEAKEKLGGSAIVDDDDAHAGVYDHKDKHRKSSFGDQRPSRAIENGWDLLDNNDVNFLMAVTMSVGGMAVASWYWDVPIQSVMGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8P1</accession>
    <name>X0C8P1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658483">
        <property type="protein sequence ID" value="EXK79077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8P1"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37285" checksum="6C2E97A889E9E1A4" modified="2014-05-14" version="1">MDTSQWNPSTGMPDLEGKVAVVTGGSSGIGLETVRFLAQNGAKVYLTTRSEARARQAKDKLTKDADINPRNVQYLVMDLYDPVSITHAVEDLKRNETKLHILINNAAASTSSTMLVDGKYEQHMVANHIGPFILINRLLPLLKAGAKDPDADVRIVNLSSTASISMLPASFKFNFDSPTCFKNPVPSYPWQWRFLGRFMFGFDMIRYAVSKAAVVLLTQELQGRLEGQNLPITCIAVHPGEVLTEGVLAINNVLVRAIARASFLTAEQGAANSLFAATAAEVKEDALKYKGKFIVPVGKLEEPNPIAKDDRQVKGLWENTVVEVNKWLMERKLALLEAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9N8</accession>
    <name>X0C9N8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADH dehydrogenase (Ubiquinone) Fe-S protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08784</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9N8"/>
    <dbReference type="eggNOG" id="KOG1687">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055737_1_3_1"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12280:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit B 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005012">
        <property type="entry name" value="PRK06411.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56770">
        <property type="entry name" value="HydA/Nqo6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase-like 20kDa subunit" evidence="4">
        <location>
            <begin position="95"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK87923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="221" mass="24835" checksum="DBF651C09FF22802" modified="2014-05-14" version="1">MTRLQLARSIARPLSITATSTIPQQAHRITDNRFDFQRRNGSSKAAKDIAPIAHPASLADVKPNNLVDYALTTLDKIANWGRTGSLWPLSFGLACCSIEMMHVSMPRYDQDRLGIIFRASPRQSDVMIVAGTVTNKMAPALRQVYDQMPEPRWVISMGSCANGGGYYYYSYSVVRGVDRIVPVDIFVPGCPPTAEALMYGVFQLQRKIRSQRASRMWYRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9N9</accession>
    <name>X0C9N9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979347">
        <property type="protein sequence ID" value="EXK79402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9N9"/>
    <dbReference type="eggNOG" id="KOG3010">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049344_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF10">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="53"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="310" mass="34283" checksum="909B7CF60D15BA98" modified="2014-05-14" version="1">MSQAQQPSDPTFRAYSAQQGATYAEHRRNYNPKLYDAIINFHKEGSGQFDTLIDVGCGPGTATRSLAPHFKTAYGLDPSEGMISTARSITTLENVKFEVSSAESLGSELANPIPDGSVDVITGATCAHWFDMPRFWEQAAKTLRPGGTVALWTAASVRVDPSMPAHEAVQEVIDDLDNLVQDYMLPGNLMVRDLYRSLPLPWTLDPPVSVFDQDSFVRKEWCTGPDSETMFFEHSPPVNLDMVEMVLGTASPVTRWREAHPEAVGTEEDVIRQIRRRIEKILGDAGVEKGKEILTGDMTGVLLLVRKRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB90</accession>
    <name>X0CB90_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphoketolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_08313</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XFP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB90"/>
    <dbReference type="eggNOG" id="ENOG502QUUF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013954_2_0_1"/>
    <dbReference type="OrthoDB" id="2532903at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005593">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018969">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019790">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018970">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019789">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_ThDP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273">
        <property type="entry name" value="PHOSPHOKETOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273:SF1">
        <property type="entry name" value="PHOSPHOKETOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03894">
        <property type="entry name" value="XFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09363">
        <property type="entry name" value="XFP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09364">
        <property type="entry name" value="XFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017245">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60002">
        <property type="entry name" value="PHOSPHOKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60003">
        <property type="entry name" value="PHOSPHOKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal" evidence="6">
        <location>
            <begin position="37"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal" evidence="5">
        <location>
            <begin position="599"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK88493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="805" mass="89957" checksum="CC206AFE6EB3B75B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBS5</accession>
    <name>X0CBS5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658452">
        <property type="protein sequence ID" value="EXK80127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBS5"/>
    <dbReference type="HOGENOM" id="CLU_3384836_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="33" mass="3475" checksum="EE1C523E094DD9BE" modified="2014-05-14" version="1">MQELEWLVKGKAGEKTGGERPVVGNAEDKGGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCM1</accession>
    <name>X0CCM1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCM1"/>
    <dbReference type="HOGENOM" id="CLU_2740150_0_0_1"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="71" mass="7767" checksum="B4638EA196C778B1" modified="2014-05-14" version="1">MFSCERGAPENKSELLEAIDSVVRTNPVAGWKGIYAVGEHVSYINGLGEDDSNNLLDYFLNLVIGYMAAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCS8</accession>
    <name>X0CCS8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCS8"/>
    <dbReference type="eggNOG" id="ENOG502SHT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012014_1_0_1"/>
    <dbReference type="OrthoDB" id="4721035at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="750"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK91966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="865" mass="95688" checksum="EA121B112528E6DF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD90</accession>
    <name>X0CD90_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_08074</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD90"/>
    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF78">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="533"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="70"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="563"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="572"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK88784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="599" mass="64435" checksum="66A8DB86DFA5A827" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGI5</accession>
    <name>X0CGI5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Borealin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_07409</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the borealin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGI5"/>
    <dbReference type="eggNOG" id="ENOG502S9QE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038589_1_0_1"/>
    <dbReference type="OrthoDB" id="2392550at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032133">
        <property type="term" value="C:chromosome passenger complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051233">
        <property type="term" value="C:spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018851">
        <property type="entry name" value="Borealin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018867">
        <property type="entry name" value="Cell_div_borealin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16040">
        <property type="entry name" value="AUSTRALIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16040:SF7">
        <property type="entry name" value="AUSTRALIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10444">
        <property type="entry name" value="Nbl1_Borealin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Borealin N-terminal" evidence="11">
        <location>
            <begin position="52"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="116"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="241"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="242"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="276"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK89949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="361" mass="38775" checksum="D112DDF19C3D7D56" modified="2014-05-14" version="1">MTMAPVNSKKQLAESPLKKTMVKHVPLHSGSPSAQPRSPIRKRTPGAITMQQKQAMIDNMQLEITERARRLRAQYNYMATTVRSRIEMRLNRVPMSMRNIKMGDLLQKFMDQEQQRAAKSASIRKQTATWAASPPKQIQSAANNLKPAPRTKKRMSDAISGDKENEVEHTETAKKRARAATTTDVSHARSGQILSPTSSNSRMANRPPSPTKSGIARPASPLKRPATASGMLSSMVEKAKATRAGAGAGRKMTTNSTASSMSTNSTAATRNKKAVPATSTTSRAPTSRPGTRTTRRSIANSESSESSNGTVIRKGPAAKSAPVKRGTASRKGTTGAVRKTTAKSNPSTASTGTGRTLRKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGV9</accession>
    <name>X0CGV9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGV9"/>
    <dbReference type="HOGENOM" id="CLU_216549_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="48" mass="5431" checksum="EE32718B7150104D" modified="2014-05-14" version="1">MLLRLLQNCLLNPMVHKLCGWEARSLATAKVSQYGKSEYCTRCKSTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHN9</accession>
    <name>X0CHN9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHN9"/>
    <dbReference type="HOGENOM" id="CLU_2757883_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="70" mass="7960" checksum="53B8C73BDA283D90" modified="2014-05-14" version="1">MGWYAEVVVNSIGFWGEFLGKTVEMASHHEKPRNLPKAVGLLMMMLRHGLSAFVWRIPVPKEPDDPTEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CI61</accession>
    <name>X0CI61_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK90963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CI61"/>
    <dbReference type="HOGENOM" id="CLU_2671143_0_0_1"/>
    <dbReference type="OrthoDB" id="5104313at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="75" mass="8142" checksum="46D7EF9A9FCED836" modified="2014-05-14" version="1">MCRGENVQCKECCRLSSRIVELCIRGELMATCPETIIEGVSLEKECSHSLMNTTGTLGGPPRRNPYRGQSIGLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIQ4</accession>
    <name>X0CIQ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_04424</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIQ4"/>
    <dbReference type="eggNOG" id="KOG1601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021761_1_0_1"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034757">
        <property type="term" value="P:negative regulation of iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000039">
        <property type="entry name" value="Siderophore transcription factor SreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF335">
        <property type="entry name" value="IRON-SENSING TRANSCRIPTIONAL REPRESSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="12">
        <location>
            <begin position="96"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="12">
        <location>
            <begin position="257"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="137"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="312"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="528"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="367"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK94300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="555" mass="59599" checksum="7C0ED30526D3B758" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJN2</accession>
    <name>X0CJN2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJN2"/>
    <dbReference type="HOGENOM" id="CLU_092493_0_0_1"/>
    <dbReference type="OrthoDB" id="4733042at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="2">
        <location>
            <begin position="73"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="185" mass="21409" checksum="197EB016140A65F8" modified="2014-05-14" version="1">MPSQPNLRAAQEVIRLRRRACDLSRSASKGAKKPLVLRQAETCYNGSSRAIIQRIVKWLEATNAADYEDILTPKMGRLRMLTDEEEEPIVAYIEWMEKTGLPASMGEIKEAATIVRRHRDPKANALHKQWYSRFYNNYPKLTTVFLKTKERSNIEYKEAGIKDTDQWFKEISAVIEDLNINASEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKY0</accession>
    <name>X0CKY0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKY0"/>
    <dbReference type="HOGENOM" id="CLU_1835248_0_0_1"/>
    <dbReference type="OrthoDB" id="5029193at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="131" mass="14850" checksum="6DAB6C766D63A5BE" modified="2014-05-14" version="1">MTKGQQAKIPAKNKKTSKKSRPKSKSKSKSYRLKTIEDPQKGQGRDSIRNTLIALQNTVFNKRKDIPAEVQGFCYRVDILHTRVLEFTLEAGVDGQDGECMDWQWEPTIPVHLVRTVYEESCYPGGAVARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLC5</accession>
    <name>X0CLC5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_03848</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLC5"/>
    <dbReference type="eggNOG" id="KOG1989">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011638_0_0_1"/>
    <dbReference type="OrthoDB" id="2018507at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000147">
        <property type="term" value="P:actin cortical patch assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14037">
        <property type="entry name" value="STKc_NAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000441">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967:SF57">
        <property type="entry name" value="AUXILIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="51"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="383"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="480"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="537"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="820"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="537"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="567"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="584"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="644"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="677"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="695"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="756"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="775"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="843"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="909"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="938"/>
            <end position="959"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK95215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1010" mass="111021" checksum="3B1B13AB429DC1F1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLM3</accession>
    <name>X0CLM3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Maintenance of mitochondrial morphology protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MMM1</name>
        <name evidence="12" type="ORF">FOQG_06079</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MMM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLM3"/>
    <dbReference type="eggNOG" id="ENOG502QUUW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5599157at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21671">
        <property type="entry name" value="SMP_Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03103">
        <property type="entry name" value="Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027537">
        <property type="entry name" value="Mmm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019411">
        <property type="entry name" value="MMM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF0">
        <property type="entry name" value="SMP-LTD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10296">
        <property type="entry name" value="MMM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="topological domain" description="Lumenal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="41"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="117"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="337"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="343"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK92178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="418" mass="46504" checksum="614D3A4CCADF5287" modified="2014-05-14" version="1">MEADTCPRLIEPTLSFTQGLIVGQLSVVLVLAAFIKFFIFGDPPSADVTASLRATERRSRTLAHKRSLLSIRSPANRGDRSQDRSLSRKKSTVLRNPPTLTIGSILSKAYYNVDSHQPESLDWFNVLIAQTIAQFRSDAQHDDAILDSLTKALNGDSRPDFIDEIRVTELSLGEDFPILSNCRIIPVDEDGVSLAPGKKFDPATAARDGLRLQARMDVDLSDMLTLAVRTKLILNYPKKLSAVLPVELAVSVIRFSGTLSISFIPSNPSQSTPTRMIFNFLDDYRLDFEIRSLLGSRSKLHNVPKIAQLVEARLHRWFDERAVEPRFQEIALPSLWPRKKNTRGPEDASTERSESIGRSRGNDAGRDHREEIRGRGGDAEIRDRGAGGTVRHRRGTRSNDSDDFSMPGSLPDFQVAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM28</accession>
    <name>X0CM28_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Insulin-induced gene 2 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_03846</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the INSIG family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CM28"/>
    <dbReference type="OrthoDB" id="205546at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025929">
        <property type="entry name" value="INSIG_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301">
        <property type="entry name" value="INSULIN-INDUCED GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301:SF3">
        <property type="entry name" value="PROTEIN NSG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07281">
        <property type="entry name" value="INSIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK95211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="43428" checksum="557046BEAF8D7B68" modified="2014-05-14" version="1">MADDGPPLIRPVPRRPFDLSLTTPTPPSENSSPPTPAPAPDPNIARFLQPTPEPASAGLSRPQSFMNLTSSTLFGIYSPTTSSSRDRVFADRDELDTPWGTGAQTPIKRPSIDDATFDFLKDRSHHMRRRSSIRVHEPAGPQKHSPSGGALVLRGLLLFVLGVGYGVLVTSRFHESDSLPPRATYNWGHLTFWGLAGVALGALFPWFDRVWENSFGDKGDEAVLETSASAKDDDPSTDWALAVRAIGAFVGIVFAIVSQPTAKPLFRITNILQRKVAWASTLQVSLTLALVNPLLWWLIDRSKPGFLLSAAVGLAGSVVLLGVNPDMMPAPTQVPFRHLVNATMAADGDMPILGGLAQQKTLETGMWMLSVLFCSCVCFGNIGRRLTLGPSTTAKGRWAGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CML5</accession>
    <name>X0CML5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GP-PDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CML5"/>
    <dbReference type="HOGENOM" id="CLU_030006_3_4_1"/>
    <dbReference type="OrthoDB" id="1058301at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46211:SF14">
        <property type="entry name" value="GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46211">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="12"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="216" mass="24073" checksum="25BFC991E5D4F23D" modified="2014-05-14" version="1">MDNPLRMTAETTRVAGHRGYSSAAPENTLSAFRKAREIGGRGVTCETDLALTRDGQLILIHDETVDRTTNGRGLVRNMDYADIAKLDAGLWFDKSFEGERVPLLRDALLLARELEIIYQLELKIYDRNDELFPKLNALINELQCADLLQFSSFDFAQLRAAKQAIPGVPTVAISHSRLINPAAVAREAQVDAVNLEIQHFPSGEAHQLQRKGNIFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMS5</accession>
    <name>X0CMS5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_03031</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMS5"/>
    <dbReference type="eggNOG" id="KOG1331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029501_2_2_1"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106335">
        <property type="term" value="F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051422">
        <property type="entry name" value="AlkB_tRNA_MeTrf/Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF21">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="92"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK95720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="280" mass="30704" checksum="ED35337A43719B11" modified="2014-05-14" version="1">MASASSATPAGDQDDRPLRQPSSQAQTNQTSAPTESESFSQSAAEEAPETYEATHVHAVYEAIAPHFSATRHKPWPRVASFLLSQPPGSLGLDVGCGNGKYLRVNPSVHLLGSDRSPALVQLARTELRRPREDGVEHDPRVSDVDVAVADGFALPYRNGAADFVICIAVVHHMSTRERRQAAIAELLALVTPKAGRVLVYVWALEQASSRRGWDASSDQDRLVSWVMRKPKGQEPGGTFQRYYHLYKEGELEEDVKAAGGIVVETGYEKDNWWVVCSRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNB1</accession>
    <name>X0CNB1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isopenicillin-N N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNB1"/>
    <dbReference type="eggNOG" id="KOG3251">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037787_1_0_1"/>
    <dbReference type="OrthoDB" id="189997at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.60.10">
        <property type="entry name" value="Penicillin V Acylase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047794">
        <property type="entry name" value="C45_proenzyme-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047801">
        <property type="entry name" value="Peptidase_C45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005079">
        <property type="entry name" value="Peptidase_C45_hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040521">
        <property type="entry name" value="C45_proenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34180:SF1">
        <property type="entry name" value="BETA-ALANYL-DOPAMINE_CARCININE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34180">
        <property type="entry name" value="PEPTIDASE C45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03417">
        <property type="entry name" value="AAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Peptidase C45 hydrolase" evidence="1">
        <location>
            <begin position="116"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="359" mass="39292" checksum="EC2B09B870353B5C" modified="2014-05-14" version="1">MLKVHCSGTPYEIGHQHGTAAKDRVVGSIAFYKDLFQESCSMNWEAVRQEAQQYIQPLQKLSPRYVEELQGLADGAGFELVDIVALNVRTEITFGLYTRVPSATIQTDGCTSAAYRQPNGEVLLAQNWDWQPEQAPNLFICHISQPGTDIPDISMVTEGGVIGKIGINSSGVGTCLNAIRARGVDNTKIPIHLALRTALESHSAREAADKLYEMGTAGSGHILVSDPSEAIGLECTSIGMKEIKFDGNGTLIHTNHLLLDHPGVDEPGWIPDSTDRIKRIAQLLDERLATSTIDHSSFFDFFKDEQGYPTAINRDQFSPGNGKATLFTINMDLAKRKAIVTMGRPTNWTERIELSPGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP64</accession>
    <name>X0CP64_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitotic spindle assembly checkpoint protein MAD2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_05705</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAD2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP64"/>
    <dbReference type="eggNOG" id="KOG3186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050394_1_1_1"/>
    <dbReference type="OrthoDB" id="21254at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF10">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="HORMA" evidence="4">
        <location>
            <begin position="13"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK92629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="234" mass="25705" checksum="563EEE3EB4F3C4B1" modified="2014-05-14" version="1">METGPLIPASQASHLLSSFTTFLTLTLHTLLYHRALYPKTTFLTARALNLPVHQSRHPGLCTWINDAVASVAAQLRKGTVRRIAIAMHAAKTFDVLERWVFDVDLFPAGWGDREEVTYNPALVEGDDDGVVNWTDVNEALRGALRRVAQKAEMMPDLPEGSTFTVAVELRDDADSPIGHPQHWIPSQPNLQPPNDTSLKQGSSLGGQSTTPIRSVQAGPLFFECWIEQSAPVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPP0</accession>
    <name>X0CPP0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPP0"/>
    <dbReference type="eggNOG" id="ENOG502S55X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062870_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031501">
        <property type="term" value="C:mannosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019433">
        <property type="entry name" value="GPI_ManTrfase_II_coact_Pga1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28022">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2 SUBUNIT PGA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28022:SF1">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2 SUBUNIT PGA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10333">
        <property type="entry name" value="Pga1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="243" mass="26703" checksum="DD261FF2FE32A4BA" modified="2014-05-14" version="1">MLSLGRAQTIYALGGLLFLFSTAIANVEKTIFTAPASLPIPQQKPSLGDLRLPILTPDAPSIRTHISRSFPSEPKDYASGVATWVLLDKLNQGQRYEFRVCWAAVQPTGFDLGVYELDTVWQTPELIQSLASYSFSRQDQEARLIEESTQTEGREREASILLLQIKASADYFTDDAALMKDPSPVHVDLILDPYLYGIVPRSLVPAAGYLVLVGAVAWFVSRSIASKLQTIAVTTDGANKKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ84</accession>
    <name>X0CQ84_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein mS38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03383</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mitochondrion-specific ribosomal protein mS38 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ84"/>
    <dbReference type="eggNOG" id="ENOG502S2R6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035429_0_0_1"/>
    <dbReference type="OrthoDB" id="5364404at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="Ribosomal_mS38_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035">
        <property type="entry name" value="AURORA KINASE A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08213">
        <property type="entry name" value="COX24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein mS38 C-terminal" evidence="6">
        <location>
            <begin position="300"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK96296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="334" mass="37080" checksum="04DB5D7F022668EE" modified="2014-05-14" version="1">MLPSSMRRVVSSAVSSTPQTGVISVLASATSKTTPVFVRNQQRRCSSSKPSKSDNGANEISAGQSVPAATSPKSGNEKRKRKSNKDASDRAASMRKLPSVPNTHHMSQEALGLSSFFSLHRPISVTQTMPRAVTDEHFASIFASRTRNNKMADTDSTLSSAIEQLEGPMAQMTIGGHEGQEGMHKVDIKNPDGTESSMYLQIDTMSGEFLPFRPPPLPQPQAAGQADSAVADIEAAEDVPQHRMYKALFTIEESIDPDGQVRIMAHSPQIVQDNQPRSFLERLALRQLKFDEAQGRRDMHAISVKRQRKLRMKKKKYKKLMKRTRVLRRKLDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQY6</accession>
    <name>X0CQY6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ankyrin repeat protein nuc-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_04924</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQY6"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2421">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002842_1_0_1"/>
    <dbReference type="OrthoDB" id="1577640at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14483">
        <property type="entry name" value="SPX_PHO81_NUC-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SPX" evidence="5">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="363"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="396"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="428"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="463"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="6">
        <location>
            <begin position="705"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="963"/>
            <end position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK93703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1002" mass="111098" checksum="8396334A74CE1C74" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRC0</accession>
    <name>X0CRC0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRC0"/>
    <dbReference type="HOGENOM" id="CLU_1875543_0_0_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="16386" checksum="B9A0772F634AA5D0" modified="2014-05-14" version="1">MSSESQQPRSKTPVLKLRPSVTTEQIVPRQKIKQPYGPWIAHPDLIDQELERRRHLVYFPPDVTRDEHRRRWKEEIPVLEAELEDCKPEDFDLRAVIQIVPRYDMQHTLCQSDHEQAKYLERHYIGAHMYNNLQFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRY1</accession>
    <name>X0CRY1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSM4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM4</name>
        <name evidence="12" type="ORF">FOQG_04281</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRY1"/>
    <dbReference type="eggNOG" id="KOG3293">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099537_2_2_1"/>
    <dbReference type="OrthoDB" id="747253at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097525">
        <property type="term" value="C:spliceosomal snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01723">
        <property type="entry name" value="LSm4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000024">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034101">
        <property type="entry name" value="Lsm4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="2"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="78"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK94088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="13378" checksum="42D60B9382B5B6BF" modified="2014-05-14" version="1">MLPLGLLNAAQGHPMLVELKNGETLNGHLVSCDTWMNLTLKEVVQTSPEGDRFVRLPEVYVKGNNIKYLRVPDEIIDQVSESQKGQQGGFRGGRGGQSRGDHSGRGDRGRGRGGRGRGRGRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTA3</accession>
    <name>X0CTA3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_10193</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTA3"/>
    <dbReference type="eggNOG" id="KOG0342">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_26_6_1"/>
    <dbReference type="OrthoDB" id="193716at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="110"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="337"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="487"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="576"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="583"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="622"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK85707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="679" mass="74122" checksum="0D335E564646F59B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTS2</accession>
    <name>X0CTS2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_02882</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTS2"/>
    <dbReference type="eggNOG" id="KOG0292">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007565_1_0_1"/>
    <dbReference type="OrthoDB" id="10261470at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22948">
        <property type="entry name" value="Coatomer_WDAD_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000002">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000022">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047312">
        <property type="entry name" value="Coatomer_alpha_WD-assoc_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016391">
        <property type="entry name" value="Coatomer_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010714">
        <property type="entry name" value="Coatomer_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF1">
        <property type="entry name" value="COATOMER SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06957">
        <property type="entry name" value="COPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003354">
        <property type="entry name" value="Coatomer_alpha_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="95"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="137"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="211"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="255"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="12">
        <location>
            <begin position="349"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="14">
        <location>
            <begin position="623"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer alpha subunit C-terminal" evidence="13">
        <location>
            <begin position="849"/>
            <end position="1218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR003354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK97845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1220" mass="136161" checksum="A3FC369250876152" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUX3</accession>
    <name>X0CUX3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_02974</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUX3"/>
    <dbReference type="eggNOG" id="ENOG502RZVZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079143_2_0_1"/>
    <dbReference type="OrthoDB" id="9970124at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="48"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK97966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="205" mass="23956" checksum="3DB5C95FAAD1CE3E" modified="2014-05-14" version="1">MGADDDEKHMQGHKHEFAHDNHDDWETQPPYTRPDEATEKRENFEKKVHGSCHCGRVQYWLNSDKPLASKYCHCIDCKKIHGAPFQWAAIFKKTDLSFENGVKNLRFYKTSSKKNEHVLPCKVGCAECGSWIMDEGRNMVLLFPTLLNLDTPQLRENFQPQCHIFYTQRVVDIPDGKDKWTKLDKDSELMKDVKDEGLRMKISRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CX20</accession>
    <name>X0CX20_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CX20"/>
    <dbReference type="HOGENOM" id="CLU_2622075_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="78" mass="8910" checksum="6B867168E0C7C647" modified="2014-05-14" version="1">MSEKAREVLECSMLQGSSRESRLAGVEMDPQMMDVDVLLMVMVWILWKFEALERPKSPPALTAADLRECEVRTDRLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXE2</accession>
    <name>X0CXE2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">mRNA cap guanine-N(7) methyltransferase</fullName>
            <ecNumber evidence="3 15">2.1.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 15">mRNA (guanine-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 15">mRNA cap methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_01586</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for methylating the 5'-cap structure of mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.56" evidence="3 15"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXE2"/>
    <dbReference type="eggNOG" id="KOG1975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020346_3_1_1"/>
    <dbReference type="OrthoDB" id="10248867at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA 5'-cap (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004971">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016899">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039753">
        <property type="entry name" value="RG7MT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189:SF2">
        <property type="entry name" value="MRNA CAP GUANINE-N7 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189">
        <property type="entry name" value="MRNA GUANINE-7- METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03291">
        <property type="entry name" value="mRNA_G-N7_MeTrfase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028762">
        <property type="entry name" value="ABD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51562">
        <property type="entry name" value="RNA_CAP0_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15 19" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9 15 16" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="5 15" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 15" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 15 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MRNA cap 0 methyltransferase" evidence="18">
        <location>
            <begin position="121"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="322"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="344"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="130"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR028762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR028762-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK98826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="477" mass="54516" checksum="79A6870B00D01DFD" modified="2014-05-14" version="1">MGRESDRDDGDERNHRKRPANDEPQDDLPQPYNAKSLQPAKRRALSPSEQPRKLKRPGARARISEAEREAIRQRQLEREREAAAEEAAEAEQERIRNNSDLVRHHYNNVPERGRDWRTRDSKIKGLRVFNNWIKSCIIQRYSPDEDHTPGSREAGRSSGKDLLVLDMGCGKGGDLNKWQQAPQPIQLYVGLDPADVSIEQARDRYRTLGSRGGRGGRGGHRRPPPRLFDARFHVKDCFGESIENLDIIQQVGFDPSPMNRRGFDVVSMMFSMHYAFESEKNARNMLRNVAGALKKGGRFIGCIPNSDVLGERVRKFNEEAAVKRAAKQSEEKNGDGSTTPQQTEPEDGELEEGEEEPTAEWGNSIYRVRFPGKTPDDGVFRPAFGWKYNFFLDEAVEEVPEYVVPWEAFRALAEDYNLELQFHRTFPEIWEAEKDDRELGPLSERMGVRERGGGPLLVSDEEMEAASFYVGFCFYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYC8</accession>
    <name>X0CYC8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15 21">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="15">IMP dehydrogenase</shortName>
            <shortName evidence="15">IMPD</shortName>
            <shortName evidence="15">IMPDH</shortName>
            <ecNumber evidence="15 21">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">FOQG_03117</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Part of the gene cluster that mediates the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world. Does not play a role in the biosynthesis of MPA, but is involved in self resistance to MPA, since MPA acts as an inhibitor of IMP dehydrogenases.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 15 21">
            <text>IMP + NAD(+) + H2O = XMP + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="15">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15 21">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer. Seems to be able to form heterotetramers composed from more than 1 of the 3 IMPDH gene products (IMD2-4).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15 20">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="15 21"/>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYC8"/>
    <dbReference type="SMR" id="X0CYC8"/>
    <dbReference type="eggNOG" id="KOG2550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="416622at2759"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04601">
        <property type="entry name" value="CBS_pair_IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000007">
        <property type="entry name" value="Chromosome 19 SCAF14664, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911:SF111">
        <property type="entry name" value="INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01240">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 19" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 15 21" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="5 15 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15 17" id="KW-0520">NAD</keyword>
    <keyword evidence="9 15 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 15 18" id="KW-0630">Potassium</keyword>
    <keyword evidence="7 15 21" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="22">
        <location>
            <begin position="122"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="22">
        <location>
            <begin position="185"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="15 16">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15 16">
        <location>
            <position position="447"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15 17">
        <location>
            <begin position="279"/>
            <end position="281"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15 17">
        <location>
            <begin position="329"/>
            <end position="331"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="15 18">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="15 18">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="15 18">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="369"/>
            <end position="371"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="392"/>
            <end position="393"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="417"/>
            <end position="421"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="514"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00058020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00062187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EXK95859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="532" mass="56885" checksum="5AFA761D05672C4A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYG4</accession>
    <name>X0CYG4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYG4"/>
    <dbReference type="HOGENOM" id="CLU_2960816_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="59" mass="6597" checksum="47B49A8EA94284C0" modified="2014-05-14" version="1">MHETLALGHFNKKVVSNEVQRLHQACIYELLIPARRWSSGEPVHGNGNLSDDLCGETQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYU7</accession>
    <name>X0CYU7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Regulatory protein alcR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYU7"/>
    <dbReference type="OrthoDB" id="5958943at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK99660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="839" mass="94209" checksum="1F3618B74E213B7D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZK3</accession>
    <name>X0CZK3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Preprotein translocase subunit YidC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_02134</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZK3"/>
    <dbReference type="eggNOG" id="KOG1239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029282_5_1_1"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF66">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="271"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="12">
        <location>
            <begin position="193"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="434"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="451"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK96703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="484" mass="53464" checksum="D9F2971BCCC8F9D0" modified="2014-05-14" version="1">MLPSRGIVRSLPSGAFQRPCGHSMSRTLGRKFEARQFGTAMKSARTPLTAGTRVGVRNISAPIVLGGIASSRQLSLWGYNIYGKKKTEEPAVEAVTTPEAPTPPKTIDPTPINEAPTPAADKFADVTRSAEPSSVLPSEFDLESIADLANPSILTMPENIGFLKEIGLDYGWGPTSVMQWVLEHVHVYTGLGWGGSIVATALLLRVIMIYPQLRSVKFSAATAKMKADPRAKESLELMKKGYQTGDREMVQKGQFIGNMVRKEYGTEVKNMFWAFVQIPFSFGLFRVINGMIHIPVPSMENAGWAWFTDLTAADPFYALPVAGTVLLVGTLKLNSKYTPPEQKAMMKNMVYVMSAVTLFATSFLGAGVNLMMVSTGAATFITAAILNNESVRRALDLPIPKIEEPVYKPPRVTQAKGIEGLRERLTDNLDNMKKSVSDQVGNMTNQYSGTAEERAEKARKEQIQKLENMRRKLERDEFEKKYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0D7</accession>
    <name>X0D0D7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar import and degradation protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02372</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0D7"/>
    <dbReference type="eggNOG" id="KOG2395">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007002_0_0_1"/>
    <dbReference type="OrthoDB" id="10251113at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040458">
        <property type="entry name" value="Vid27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013863">
        <property type="entry name" value="VID27_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040979">
        <property type="entry name" value="Vid27_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040768">
        <property type="entry name" value="Vid27_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913:SF0">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08553">
        <property type="entry name" value="VID27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17748">
        <property type="entry name" value="VID27_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17747">
        <property type="entry name" value="VID27_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vid27 N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Vid27 PH-like" evidence="3">
        <location>
            <begin position="245"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar import/degradation Vid27 C-terminal" evidence="2">
        <location>
            <begin position="424"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK97023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="808" mass="91153" checksum="3DF0CE076F10B648" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0L7</accession>
    <name>X0D0L7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0L7"/>
    <dbReference type="HOGENOM" id="CLU_2960850_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL00321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="59" mass="6539" checksum="AD25F1ED76598BBB" modified="2014-05-14" version="1">MDAMKSSWTEVFLHLDDPWQVSEDRWLASKGCKTTSMTLADISNDNIVHDASRPASGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1F7</accession>
    <name>X0D1F7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 13">Mannosyl-oligosaccharide glucosidase</fullName>
            <ecNumber evidence="11 13">3.2.1.106</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Glucosidase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_02604</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>N(4)-(alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + H2O = N(4)-(alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:55988"/>
            <dbReference type="Rhea" id="RHEA-COMP:12806"/>
            <dbReference type="Rhea" id="RHEA-COMP:14355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:59082"/>
            <dbReference type="ChEBI" id="CHEBI:132537"/>
            <dbReference type="EC" id="3.2.1.106"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="14">Glycan metabolism; N-glycan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum membrane</location>
            <topology evidence="1 13">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the glycosyl hydrolase 63 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.106" evidence="11 13"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1F7"/>
    <dbReference type="SMR" id="X0D1F7"/>
    <dbReference type="eggNOG" id="KOG2161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007380_1_0_1"/>
    <dbReference type="OrthoDB" id="410058at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004573">
        <property type="term" value="F:Glc3Man9GlcNAc2 oligosaccharide glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009311">
        <property type="term" value="P:oligosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000027">
        <property type="entry name" value="Probable mannosyl-oligosaccharide glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.110:FF:000003">
        <property type="entry name" value="Probable mannosyl-oligosaccharide glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.110">
        <property type="entry name" value="Glycosyl hydrolase family 63, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031335">
        <property type="entry name" value="Glyco_hydro_63_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031631">
        <property type="entry name" value="Glyco_hydro_63N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038518">
        <property type="entry name" value="Glyco_hydro_63N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004888">
        <property type="entry name" value="Glycoside_hydrolase_63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412:SF11">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03200">
        <property type="entry name" value="Glyco_hydro_63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16923">
        <property type="entry name" value="Glyco_hydro_63N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937578" description="Mannosyl-oligosaccharide glucosidase" evidence="15">
        <location>
            <begin position="20"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 63 N-terminal" evidence="17">
        <location>
            <begin position="38"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 63 C-terminal" evidence="16">
        <location>
            <begin position="302"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK97388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="813" mass="92552" checksum="84E19F5B1C5BBB2B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1T3</accession>
    <name>X0D1T3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA polymerase alpha subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_00579</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA polymerase alpha subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1T3"/>
    <dbReference type="eggNOG" id="KOG1625">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014923_1_0_1"/>
    <dbReference type="OrthoDB" id="336885at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.60:FF:000005">
        <property type="entry name" value="DNA polymerase alpha subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.60:FF:000008">
        <property type="entry name" value="DNA polymerase alpha subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016722">
        <property type="entry name" value="DNA_pol_alpha_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054300">
        <property type="entry name" value="OB_DPOA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061">
        <property type="entry name" value="DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061:SF12">
        <property type="entry name" value="DNA POLYMERASE ALPHA SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22062">
        <property type="entry name" value="OB_DPOA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018300">
        <property type="entry name" value="DNA_pol_alph_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase alpha subunit B OB" evidence="9">
        <location>
            <begin position="217"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="8">
        <location>
            <begin position="363"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR018300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXL00377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="656" mass="71304" checksum="9FD9FEF7B7670473" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3F5</accession>
    <name>X0D3F5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">IMP-specific 5'-nucleotidase 1</fullName>
            <ecNumber evidence="12">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_01118</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>IMP + H2O = inosine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27718"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="3.1.3.99"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ISN1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="12"/>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3F5"/>
    <dbReference type="eggNOG" id="ENOG502QR24">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006190">
        <property type="term" value="P:inosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071590">
        <property type="term" value="P:nicotinamide riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071592">
        <property type="term" value="P:nicotinic acid riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009453">
        <property type="entry name" value="ISN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213:SF1">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06437">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028836">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR028836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK98108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="478" mass="53286" checksum="1D8A211D41130EC9" modified="2014-05-14" version="1">MTTRYRVEYALKTHRRDQFIVSLIHHFSISIPASHVPLSTPHIRLSQLTRIAEWVKGLLAVPFVLYSQPTGVFGDGPSVTQMAEEAHRRYAEIMRDVELMIDDHISRQQDDTMLPSKLRMLIPTAGPFFTRLPLEAAFKYQDRKRYISSRRFVAPSFNDVRQILNSAQSMAVTNGSLQLATFDGDVTLYDDGFNLEPSSPVIPRLLDLLRKNIKIGIVTAAGYTSADRYYERLHGLLDAITESTDLDPIQKQNIVIMGGEANYLFEFSPSSPYKLAPVPRTQWLTPEMASWSDADITRLLDVAEGALRDCVNNLNLPAMIMRKDRAVGIIPKTPGTRIARESLEETVLVVQRILELSSLGSSEERPTKHRPNSPPIPPSVASQSRRVPFCAFNGGNDVFVDIGDKSWGVTVCQQWFGSKENGGAIRGENTLHVGDQFLSAGSNDFKARSVGTTAWIASPAETVELLDELADLMQKKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3M3</accession>
    <name>X0D3M3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3M3"/>
    <dbReference type="HOGENOM" id="CLU_150197_1_1_1"/>
    <dbReference type="OrthoDB" id="4083871at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42077">
        <property type="entry name" value="YALI0F30239P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42077:SF1">
        <property type="entry name" value="YALI0F30239P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="117" mass="12900" checksum="1F0EF237CD09F444" modified="2014-05-14" version="1">MAKQPSALSQVLPLIIVFALLSVGGWVGYQVYISVAKMSDAASERMGKKNVVFTKDGVKVGVKQIKNENYVDATQSWFVKAWNLGTTSDASQRCVHRGIFSRERGIGSDNVYSKKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4X9</accession>
    <name>X0D4X9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Expansin-like EG45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4X9"/>
    <dbReference type="eggNOG" id="ENOG502S9P9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026963_3_1_1"/>
    <dbReference type="OrthoDB" id="406505at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22271">
        <property type="entry name" value="DPBB_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.760">
        <property type="entry name" value="Expansin, cellulose-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036749">
        <property type="entry name" value="Expansin_CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049818">
        <property type="entry name" value="Expansin_EXLX1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041144">
        <property type="entry name" value="expansin_EXLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49590">
        <property type="entry name" value="PHL pollen allergen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937641" description="Expansin-like EG45 domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="23302" checksum="A31A202E2AA4132B" modified="2014-05-14" version="1">MKFTSVLLAGPALVAGRYLSDEVTSGTSTHYGGNVSGGNCGFVSYTIPSGIYGTAFSGPNWDNAGVCGSCIEVTGPTGKKIKAMIVDKCNECNKGHLDLFENAFTAVGGTNGLVQTSWRLISCDITTPLVLRNKEGTSAHWFSMQVRNSNLPVKSLEVSTNSGKTWTGTTRRDYNFFENPSGFLVDTVDVRITSSTGSTIIVKNVGAKPSTEYPASGNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5D5</accession>
    <name>X0D5D5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_01268</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5D5"/>
    <dbReference type="eggNOG" id="KOG2615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_10_2_1"/>
    <dbReference type="OrthoDB" id="196650at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000223">
        <property type="entry name" value="Major facilitator superfamily domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF31">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="12"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK98329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="449" mass="48066" checksum="DFE6FB2EEFA6C209" modified="2014-05-14" version="1">MSTFDPAARKRVLRVIAVSLLLDLISFTFILPLFPKLLEFYRDREVQEPIGHDGPQTLLQTVLSGLHRYKASFSRPIESRHDIVLLGGALGSLFSLLQAIASPLIGALSDRYGRRKALLASMCGNILSVLLWVAAVDFRTFIASRVVGGLSEGNVQLATAMASDISDESSRGATMALIGACFSIAFTFGPGLGAWLSTFSTFTANPFAAAAGFSLALIVVETVYLYFSLPETLPSLRGAQAKDGRKKKAIHKAIERTNSHFLLNAIHFVFLLFFSGMESSLSFMTYELFSFTSGKNGRLLGYVGLVASILQGGVTRRLPPLMSVRIGTLACLASFVLLGQVNTIGGLYIAATCLAVTSATVVTGLNALSSFEAHEDERGNKLGMLRSWGQLGRGLGPILFTSVYWWAGREVAYGMGATGIAVVAAAVFGGLKTPKGMNTQGKKVEGKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0D782</accession>
    <name>X0D782_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D782"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF414">
        <property type="entry name" value="CONTAINING AMINE OXIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="80"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="549" mass="62172" checksum="E8860791D2A73C5B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0DC53</accession>
    <name>X0DC53_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Thiamine phosphate synthase/TenI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_00971</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>4-methyl-5-(2-phosphooxyethyl)-thiazole + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H(+) = thiamine phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17957"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">In the C-terminal section; belongs to the Thz kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="17">In the N-terminal section; belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DC53"/>
    <dbReference type="eggNOG" id="ENOG502QS2M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019943_1_1_1"/>
    <dbReference type="OrthoDB" id="4994at2759"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00139"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004417">
        <property type="term" value="F:hydroxyethylthiazole kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01170">
        <property type="entry name" value="THZ_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000042">
        <property type="entry name" value="Probable thiamine biosynthetic bifunctional enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000104">
        <property type="entry name" value="Thiamine biosynthetic bifunctional enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00228">
        <property type="entry name" value="Thz_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000417">
        <property type="entry name" value="Hyethyz_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006830">
        <property type="entry name" value="PRK09355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00694">
        <property type="entry name" value="thiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857:SF23">
        <property type="entry name" value="THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857">
        <property type="entry name" value="THIAMINE-PHOSPHATE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02110">
        <property type="entry name" value="HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01099">
        <property type="entry name" value="HYETHTZKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="Thiamin phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamine phosphate synthase/TenI" evidence="18">
        <location>
            <begin position="10"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00061146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00061283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXL01124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="508" mass="53061" checksum="0595C5A369797627" modified="2014-05-14" version="1">MAKPTVNYGLYLVTDSTPEILGDRSLEEVVEASLRGGVTILQYRDKHSERPVAVDTAKKLHAIARRYNVPLLINDRVDIAAEIDCEGVHIGQDDMAYEEARKLLGPNKIIGVTASSKEEALKACEAGADYLGIGTVYSTQTKKDTKSIIGPSGVRDILSALYDAGYGSVPTVCIGGINARNTAPVLAAAGSPSKSLDGVAVVSALIAAPEPATAARDLLGKVIVAKIPEVIRAVADKTPLSHNMTNLVVQNFAANVALCVGASPIMANYAQEAADLAKLGGALVVNMGTVTPDGLKNYLQAIKAYNEADRPIVLDPVGAGATTVRRNAVKTLLDAGHFTIIKGNEGEIQTVAGATITQRGVDSTSSLTFPQKASLVRSIALHRHTVVILTGATDLVSDGTRTLAISNGHPYLGEVTGTGCTLGTTVSAMVAAYGADPLLAAVAATVMFGLAAELAAERNEVRGPGSFVPTFLDELYNIRKSTAKGDLRWLNMAKVKAVEVDIDVIPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DDN5</accession>
    <name>X0DDN5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DDN5"/>
    <dbReference type="HOGENOM" id="CLU_3299402_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="40" mass="4151" checksum="FB8C528A1643C2C5" modified="2014-05-14" version="1">MAKAALLSEKMEGEINYLGLSRWGDGGVASDNLAPASDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0DY03</accession>
    <name>X0DY03_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DY03"/>
    <dbReference type="HOGENOM" id="CLU_3320075_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="39" mass="4321" checksum="829F0FBC59874A9A" modified="2014-05-14" version="1">MKQQEIYKRPVVSVMSGTRAEMASVDGAPNGVWEIVWGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0E194</accession>
    <name>X0E194_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_00418</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E194"/>
    <dbReference type="OrthoDB" id="2213137at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF130">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXL00118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="49561" checksum="006FF7E544731366" modified="2014-05-14" version="1">MFGKDVEKTPTRRQSSPCPSEGNPEDPQNLHHTISNTNAPPPVFDPESFDPPDGGFTAWSQVLAGVFINCLAWGYPASFGVYQLHYEESLGLPSSQISWIGSCQTFLTFAFCGPAGRLADAGYTRETVAFGSFLAILGTFMTSLCKEYWQIFLSQGVCTGIGLALLFMPAVTVVGSYFKAKKAFALALAATGTGLGSIIFPATLQYLIPQIGFPWAVRCAGFVALVLIVAANLILKPYLAPRKSGPLIEWEAFRELPYLLFVLGAFLNFYALYFGFFYINVYARNVIGFTAVEAVSLLLIVNAMSIPARPIMGYLADNILGPINAFLIGMTALSVMVYCWIGVKSVAGMYAFCVFFGFVNGACQGTFVGANASLTKGKRPPDFCLVVLLYMTDQVIKIPARWVLASVWFRRFLHLPVWPDHRLLVPSWINRMAILYMHRFGVVLCFCLVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0B199</accession>
    <name>X0B199_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979736">
        <property type="protein sequence ID" value="EXK75890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B199"/>
    <dbReference type="HOGENOM" id="CLU_158098_0_0_1"/>
    <dbReference type="OrthoDB" id="5064780at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF1">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="111" mass="12048" checksum="848714CF18DA76BE" modified="2014-05-14" version="1">MGDITYGACYIDDYTARALGYDLLVPYSHDCLIPVEVTKTKVLYVFVDIGINASHILASLERNFSSSNQCCVWIRNRDVLGPRSWLSLSGIQGAGGKTSRVTVLVSSCGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1I8</accession>
    <name>X0B1I8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980025">
        <property type="protein sequence ID" value="EXK75611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1I8"/>
    <dbReference type="HOGENOM" id="CLU_2794028_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="58" mass="6947" checksum="F999A4C1685F33CB" modified="2014-05-14" version="1" fragment="single">QHYQEYQTPQQHNENLVNLYHQALAAHDFKCWRVIGNGDTCMICFDHALRQALWETQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1K9</accession>
    <name>X0B1K9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_19232</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658778">
        <property type="protein sequence ID" value="EXK76005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1K9"/>
    <dbReference type="HOGENOM" id="CLU_070111_0_0_1"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF27">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="50"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK76005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="264" mass="27695" checksum="88BFD5F0A905F108" modified="2014-05-14" version="1">MESLPCSSMSRSPLKDHAEVHLTILDDGESSQALSTGAATPLTLIRRTAVVFQLCGVNFATSASSGLIVIGLPQLTSDLNIPQSLAFWPSSVQGLATASALLLSGAVADVLGPLSVNLSGCILNGVFMLSCGFIKSIQQLITMRALQGVAIAMHFSSSVALVADTQPRGQSRNISFACLGLSQLLGFTFGLVVGGVLVDTVGWHSGWYLYGGVTLLLSAVGLWSLPKSEPLGFRNIFVDLIYRVDWIGALLASVSMASISYFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1T1</accession>
    <name>X0B1T1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979610">
        <property type="protein sequence ID" value="EXK76085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1T1"/>
    <dbReference type="HOGENOM" id="CLU_702162_0_0_1"/>
    <dbReference type="OrthoDB" id="5088056at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="473" mass="54024" checksum="D49ADE9683C08B1E" modified="2014-05-14" version="1">MNQNRSGQPSPSNNGPECPSDIGSARTAAPPVLEVIFEDPQLRRETAVRAEPSRELPKHFVSLVRDMSQENGQLKKRREQGLDDPRKVWDQLAKLEKLDLTRYPQQRATLEPWHELVIIAATMVDEHLGNKDIALSTITQLNRRELSHETINRDKRVIREMIKLMDDLYLQWKHELALEIFILLDIPMSVLRLQSAQKFNALTLQLKNHTPSTKIKSFLKLYIPFLVLLLRPKYRLSDIQKALQTSLFNQADWDTFREALQRPAPKYDPIRDIWTNHRPVPSVQAPAPEAPEPQQRISTPIVNERNAPTSNLELSEFIDYKRNYPAKIHTPISGFKAFETSPDLQRKVAYASENQTGYTPTGPDLFAYDWADDIHGPVMRQVLEDLAKYGFLQAEEVYVARVSVSHGLTSTIVPAGHLQIVVPIEDSHWPVSLSNQESSTTVKWNTGIMYTLDQKTKLSASGWIKYMSLLAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1V2</accession>
    <name>X0B1V2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979902">
        <property type="protein sequence ID" value="EXK75701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1V2"/>
    <dbReference type="HOGENOM" id="CLU_2015418_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="123" mass="13407" checksum="1C5040C6A3FC1C8C" modified="2014-05-14" version="1">MGTGTWDFFDWAVGKAWVTIGSVGKACKFGWKRYDDTYYTCVETFRAFENAGVLPCADVLRAENMSQATQASLAPHPCDAVTLMKAKVKKEQNGEATNGVSHQGLKNGHHNGHVESGDLDVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2N1</accession>
    <name>X0B2N1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658728">
        <property type="protein sequence ID" value="EXK76375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2N1"/>
    <dbReference type="HOGENOM" id="CLU_000692_0_1_1"/>
    <dbReference type="OrthoDB" id="5096121at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1030"/>
            <end position="1068"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1080" mass="122925" checksum="5975EE93D4C68885" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3W7</accession>
    <name>X0B3W7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cutinase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_18811</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979505">
        <property type="protein sequence ID" value="EXK76451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3W7"/>
    <dbReference type="eggNOG" id="ENOG502S6TR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040058_6_1_1"/>
    <dbReference type="OrthoDB" id="3225429at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF9">
        <property type="entry name" value="CUTINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936131" description="Cutinase 1" evidence="3">
        <location>
            <begin position="18"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK76451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="22900" checksum="432EE1EDB21011AF" modified="2014-05-14" version="1">MLSQFITFLALAGCAVAAPSPRAAKCTSYTIINTRGTGEIQGPSAGFRTMNSQITSQVPGGKIYNTVYLAGYDQNSAQGTQDIIREVKSVLASNPSECFILEGYSQGAAATVNALSQLTGSAGDAVKGVFLIGDPLHKSGLACNVDNNGGTTTKNVNGLEAFGGAGIPQNWISRTLDVCIFGDGVCDTTHGFGINAQHLQYPNDAATQNLGTTFVVKKLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4Z0</accession>
    <name>X0B4Z0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979441">
        <property type="protein sequence ID" value="EXK76816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4Z0"/>
    <dbReference type="eggNOG" id="ENOG502SHN1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1510686_0_0_1"/>
    <dbReference type="OrthoDB" id="2906425at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF55">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="19763" checksum="DBA916EB7A0EBCAB" modified="2014-05-14" version="1">MSTPYVPPDDGTATQHDGTDSLAIKNTLLRRLLTRIALKTTARLYEHNGPCIPISKHLIVKTGPFVHLTEAATMSFVAANTSIPVPAVYSSFIYKNRAFIVMERIQGNSLAEAWPTLSDADLDNIFAQLRQMFQELRALPPPPGTGVESCRGGSLRDSRIPRSRPRFGPFKCVQDFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6F7</accession>
    <name>X0B6F7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658618">
        <property type="protein sequence ID" value="EXK77346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6F7"/>
    <dbReference type="HOGENOM" id="CLU_002639_3_1_1"/>
    <dbReference type="OrthoDB" id="1862401at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="203"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="705" mass="79574" checksum="26E1141D2A89D358" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6X1</accession>
    <name>X0B6X1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979385">
        <property type="protein sequence ID" value="EXK77521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6X1"/>
    <dbReference type="eggNOG" id="ENOG502RNIW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1586518_0_0_1"/>
    <dbReference type="OrthoDB" id="4965074at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936756" evidence="1">
        <location>
            <begin position="19"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="168" mass="18254" checksum="10C4837DA78E7FC2" modified="2014-05-14" version="1">MKLLTLISAFATATLVSADQRAQLSAPDGSVHHLSARDSTCPRPMCKTPASQGPNGPPACGDSYAACKFDQFPCDEHFSPKVTDTHHCYCILANKKAMDAYCQERGFKCGTNPWKYYYAVECHGAVSNQVCNKDCHDQGRGYGRIDKAHPNGACACDKPNPPYDTCKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-09-13" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0B771</accession>
    <name>X0B771_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17678</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658588">
        <property type="protein sequence ID" value="EXK77621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B771"/>
    <dbReference type="HOGENOM" id="CLU_128845_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="20461" checksum="B4B15BC5F3704AC8" modified="2014-05-14" version="1">MSTAVAIDDVSHYFDEHGFLYRPLKRVGTMVQNLYDDERLRDPTANFDFFKPILESDPVLRKLLEGYPVTVLEINWPWGKFDEYYCWGRSSPFVFKPSLAIYVLAPGSKATCCDRSHKREVKGLSRHPNGTLPLSNESMEPYEKKDIESEFGGVLCVHPLLGHRMPNGVSKFFTVRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B790</accession>
    <name>X0B790_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979369">
        <property type="protein sequence ID" value="EXK78015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B790"/>
    <dbReference type="HOGENOM" id="CLU_101855_0_0_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="169" mass="19253" checksum="8B8AA13C47637822" modified="2014-05-14" version="1">MQHVSNALCALREAVLHKRAPPATKATTKGIWRYHFRTQFQPDTELAAVSVEWYDDASEWFSGCQKRSIEGRDFEESIVRIFHSFYNNGTAEVRHEPVFKDEYRILRRSWDRHLVENGSAVDLEQGNPKRSMGHMQSHGNDNGTVGLSADWLNASGNGFLVVLSSHSTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7X8</accession>
    <name>X0B7X8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sterigmatocystin biosynthesis monooxygenase stcW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_17438</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658565">
        <property type="protein sequence ID" value="EXK77876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7X8"/>
    <dbReference type="HOGENOM" id="CLU_006937_6_2_1"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK77876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="60468" checksum="56C05E8CFBE01A74" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8T7</accession>
    <name>X0B8T7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Subtilisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_16765</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979355">
        <property type="protein sequence ID" value="EXK78575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8T7"/>
    <dbReference type="HOGENOM" id="CLU_011263_1_4_1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000014">
        <property type="entry name" value="Proteinase K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF58">
        <property type="entry name" value="ALKALINE PROTEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935579" evidence="8">
        <location>
            <begin position="21"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="10">
        <location>
            <begin position="35"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="9">
        <location>
            <begin position="163"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK78575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="413" mass="42324" checksum="4ED60B229CC23D30" modified="2014-05-14" version="1">MASLLRLALYLGAFLPAALAAPTAPSKRSDEIPGKYIVTLKSSASSAKVESHLQWVGDVHRRSLSKRETAGIEHTFNIKNWNAYAGQFDEDTIKEIEASPEVAFVEPDKIVKLNFEQSSELSDRALTTQSGAPWGLGTISHRTSGSTSYIYDTSAGEGSYAYVVDSGVLISHSQFGGRAVAGYSIFSGANTDTLGHGTHVAGTIAGSTYGVAKKANIVSVKVFQGAEGTDSGVLAGFNWAVNDITSKGRAGKAVINLSLGGDASQAWVTAIDAAYNSGVLSVVAAGNGDEDGNPLPVSSQSPANAANAITVAALTSAWRPTSFTNYGAGVDIFAPGQSILSAWIGSNSATNSISGTSMASPHVAGLALYLKVLEGLATPASVASRIKTLGTSGKITGTLSGSPNLIAYNGNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9V7</accession>
    <name>X0B9V7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980030">
        <property type="protein sequence ID" value="EXK75608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9V7"/>
    <dbReference type="HOGENOM" id="CLU_2941847_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="60" mass="6800" checksum="926C9287F526F29F" modified="2014-05-14" version="1">MIVRNHKISWQLWNECPLESVAAFFPPAQVRSAKLSFAVEGRTLLQAPVGSERQNGVFRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC51</accession>
    <name>X0BC51_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_16014</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658473">
        <property type="protein sequence ID" value="EXK79361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_35_0_1"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000054">
        <property type="entry name" value="ABC multidrug transporter atrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="511"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="555"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="586"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="620"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="723"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1141"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1175"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1214"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1256"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1292"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1409"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="118"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="810"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1091"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK79361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1455" mass="162173" checksum="00C10AB7279676AA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCI4</accession>
    <name>X0BCI4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_15892</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658468">
        <property type="protein sequence ID" value="EXK79501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCI4"/>
    <dbReference type="HOGENOM" id="CLU_007884_0_1_1"/>
    <dbReference type="OrthoDB" id="2219495at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF15">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="14"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="416" mass="45400" checksum="EA8842AAF53E066C" modified="2014-05-14" version="1">MSDKALSPTKSDAIIIVGAGIFGLSTAIHLAQRGYRNVNIFDRQPYEKTLYSYTQGCDAASADINKIIRSAYGSQKIYQDLGLEAIKSWNSWTEELLHDGAAVPPGMTTSDNIWINNGDLACTDEKTLPPFQRATIETKEKGLASHMQPFAKELLGVLDTSGGITLADKACRFALHKAKRLGVVSGISTADGKTHQAALTIAACGGWTPSIVPELDGFAETTAGCVVIFKLPEDLRERFSPSRFPAWSFKSTDGAEAGLYGFPVDENGSIGSVPVTRWSEDEQLTKIPAQAIKVIRRFTNQYLPELASLDIWLTSLCWYTDSFDNHFIIDHVPKKEGLMVATAGSGHAFKYLPTIGNWVVDIIEGKSLDRPAVKAWRWRSPKEGNAPFNKLMEGSSGERALSNVQLVSVDALISKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCT6</accession>
    <name>X0BCT6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979345">
        <property type="protein sequence ID" value="EXK79601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCT6"/>
    <dbReference type="HOGENOM" id="CLU_3359703_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="36" mass="4272" checksum="687A0FFBEDC1D5A4" modified="2014-05-14" version="1">MSTMWSSDVLGASPSRTTSMHIFASDRLRYYRRQIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD88</accession>
    <name>X0BD88_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979447">
        <property type="protein sequence ID" value="EXK76778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD88"/>
    <dbReference type="HOGENOM" id="CLU_009600_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF7">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="31"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="463" mass="50771" checksum="F51BCB91BC081035" modified="2014-05-14" version="1">MGREVRDKHKLTASEALGKIQADEISVQEYAESLLERIKARDEDVKAWAYLDEKRVIQEARLLDEIPKENRGPLHGLPIAVKDVIYTKDMPTQFNSPLYDGHFPETDAASVRILRHAGALMFGKTTTTEFAAIHVGPKTHNPHDPLRTPGGSSSGSGAAVADFQAPMALGTQTGGSMIRPASFNGIYGFKPTWNSVSREGQKIYTLMYDTLGWYGRCVEDLVLLADVFALQDDEDEDRSFQGIAGARFAICKTSIWPMAGPGTQDALARAADLLRSHGAEAHELELPSAFDDVPEWYRIGLHTEGRTSFLPEYRVGKDQIGQVLIEHVENSDNFTRKTQLMASDRLAGMRPAFDKIASRYAAIITPSVPDEAPVGLENTGSHVFCAMWSGLHVPVLNVPGFKGDHGMPIGLSLVAPRYHDRHLLEVGKAVGEIFEAEGFLGDEDRVMERDGDSAENGSKSNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDU6</accession>
    <name>X0BDU6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658453">
        <property type="protein sequence ID" value="EXK79991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDU6"/>
    <dbReference type="HOGENOM" id="CLU_2891998_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="63" mass="6763" checksum="4F4F03F03322D65E" modified="2014-05-14" version="1" fragment="single">PPAASQYWPEGLDVRNPGAAVEALQQVADAAPVSGAGYRDSESQRLESGSTWASRLEHVNQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BG66</accession>
    <name>X0BG66_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14395</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658429">
        <property type="protein sequence ID" value="EXK81150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BG66"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF10">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="24"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK81150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="524" mass="57759" checksum="DF7C90EEB28BBCC4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGL4</accession>
    <name>X0BGL4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658432">
        <property type="protein sequence ID" value="EXK80961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGL4"/>
    <dbReference type="HOGENOM" id="CLU_050403_0_0_1"/>
    <dbReference type="OrthoDB" id="5098550at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935707" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="2">
        <location>
            <begin position="224"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="301" mass="31054" checksum="E934371200EC53D0" modified="2014-05-14" version="1">MIACRIVAVIGLLAAGVQAGPCKPSSVVTTTADATSTYSVSNTGTATSGDIATTTETTLTPSSTGYSCVNNEKTPFPAGVLCDTKGIGADPNMLTVPNVFCDLWGGRIQGTDGSNTDFSWYSLDCFCDLPELSTTSATATAATATTGTTSLTTDTAITNTATMDTIILTSETATTELETSSTVLTTSSAALTSSTETTTAAATTTTIATSAPSCPGGFPSGSSCGVSKQYIGTGSYIKDIDGTYTLDECLQFCIDHPTCNLFAYAATWCELWNGEYATTGSSVNFSWYELDCFCVERAPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJH0</accession>
    <name>X0BJH0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658487">
        <property type="protein sequence ID" value="EXK79023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJH0"/>
    <dbReference type="HOGENOM" id="CLU_001248_2_1_1"/>
    <dbReference type="OrthoDB" id="4917073at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="125" mass="14307" checksum="A5A954E3DA51E0F4" modified="2014-05-14" version="1">MSECQKKRPWLRKNVSRRGLPCAAAFACTDYKVQSKTLNRVVLELRGARTTNIDGEAVPAQCDPYSLYVQLSRCRTLRGITLLSEVRERDFVGNRVPENMVAAEEKLERLSDKTIRDAACWDWSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJI2</accession>
    <name>X0BJI2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Efflux pump antibiotic resistance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979354">
        <property type="protein sequence ID" value="EXK78619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJI2"/>
    <dbReference type="eggNOG" id="ENOG502RYDN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061199_0_1_1"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="31705" checksum="8C52FD30897CBD3F" modified="2014-05-14" version="1">MASLTARSSPPKDGIKIIHAGLYRTGTASMAAAYHILGYKAHHALHNEWHEPWGKLEQAAEATFPHLIHLPDYTHNGPRSGFTREDWQSLWGDYDVATDIASTFTLELIKVYSDAKVVIVQRKFEDWWPSFHSEILVSVFEATWLQKFLTWYVLRFRALHAMRKILAGFFSVDEYSVEAITPAIARHAYEEFYSKVREAVPKERRLEYSLGDGWEPLCEFLGKDVPDVEFPRVNDRKTHSEDMERLVAKLLRVSMRVLGPYLVGFLAVAVVFYAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLB8</accession>
    <name>X0BLB8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tryptophan dimethylallyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLB8"/>
    <dbReference type="eggNOG" id="ENOG502S2XP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1555337_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017795">
        <property type="entry name" value="ABBA_NscD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40627">
        <property type="entry name" value="INDOLE PRENYLTRANSFERASE TDIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40627:SF4">
        <property type="entry name" value="PRENYLTRANSFERASE ASQH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11991">
        <property type="entry name" value="Trp_DMAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="172" mass="19283" checksum="F2C891D130CBD96E" modified="2014-05-14" version="1">MPGKLDLSTIDSVTFHSLHHIKNKTGPAVDIHQQYWNQTAGSTLKRFLASAGYDARSQCHILDQFSNLVAPFLGSSPALGEPQWKSFMTDNHCPVELSWDFHVANSQPTIRYSMEPIGLKAGTAADLYNNGVDEEFAKRAIRAFPGTDTTLFNHFYDYFNGQWTADQGWARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLX0</accession>
    <name>X0BLX0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658455">
        <property type="protein sequence ID" value="EXK79893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLX0"/>
    <dbReference type="eggNOG" id="ENOG502RAWF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064333_0_0_1"/>
    <dbReference type="OrthoDB" id="5073284at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="265" mass="29795" checksum="524724AB676C84F8" modified="2014-05-14" version="1">MEKLTKSHLQEVGNEQVSQRILQWTDGIESCDQSDPNTSIHSPSKSSTDGYETSNDSFYTASEGGSKESAATIGRSVIPEPATSDVRIDIPQQETFEDANETVNPHPYLTINMDFAREAIYIYEMMKEGVIDDEWNSKSCLLTRTLIHDRPASSSGRLGWRCDVNYDPDGVYTGAVVVLFMPDRDFVKKIKQGEVVFDQSTDMKPISVLMQTIDPDFSGPEKRLAYRVLAWKVCGSEDCVWMDRQGHPINRGDPKVIPNIIHLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLX8</accession>
    <name>X0BLX8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_12812</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLX8"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000001">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF9">
        <property type="entry name" value="DICARBOXYLIC AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="468"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="39"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK82846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="533" mass="59106" checksum="5F8A34911682D76C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLY3</accession>
    <name>X0BLY3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12822</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658409">
        <property type="protein sequence ID" value="EXK82856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLY3"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000018">
        <property type="entry name" value="MFS transporter permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF24">
        <property type="entry name" value="NICOTINIC ACID PLASMA MEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="43"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK82856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="481" mass="52862" checksum="8B509499052FE82E" modified="2014-05-14" version="1">MEAAEKQSELKMPLEQELDQNSGEMNDITEVEKKVLSKFDKFVMPQMALLVLFAYLDRTNIGNARVFGFEEDTGMHGTQFNDVSMYFYISYVVFETPWVLAVKKFGPGRVLAIAIISWSIITLGTGFVNSYGQVVACRVLLGFFEAGLFPSLTFVVSQIYPPASQGKRVAVLYVSIALSGALGGLIAYGIQSMGARHGLSAWRWLFIIEGAISLVIGAVCWLSLPTSPQTAWFLSEEEKSTMVLIKERNHPFKETEGFSWKQVVMALTDPLVWLASVSLFCASIALFGFGTFLPTLLKGLDYTSLQANYLSIPVYVLASIFTAATTYVSDRLNRRAICLIHSPLLVIVGYAIVVGTGHKAAGFFAMFLVGGGVYSFNTVLVTWVSNNMQPDYKRSVAISMLISLANASGMAASQIYPIQDAPRYVMGNAISLGGEVLALVCVGLIYALLKYRMRQKERLIAEGKDGNGKEGDQSLEFEYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPM5</accession>
    <name>X0BPM5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658435">
        <property type="protein sequence ID" value="EXK80848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPM5"/>
    <dbReference type="HOGENOM" id="CLU_3087336_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="52" mass="5748" checksum="A533A194CBA67FCB" modified="2014-05-14" version="1">MLSNIYAIAPTTLNRPSTTGRAQHATPPEEARPLAEELQEIPMETDKEEGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQH9</accession>
    <name>X0BQH9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cargo-transport protein ypp1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11639</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in endocytosis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YPP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQH9"/>
    <dbReference type="eggNOG" id="ENOG502S2NV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051722">
        <property type="entry name" value="Endocytosis_PI4K-reg_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23083:SF464">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT DOMAIN 7, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23083">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN, TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1143"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="711"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1065"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="760"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="789"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="807"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="819"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1065"/>
            <end position="1090"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1191" mass="131347" checksum="34AFBF1F7527315E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQN8</accession>
    <name>X0BQN8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658436">
        <property type="protein sequence ID" value="EXK80789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQN8"/>
    <dbReference type="HOGENOM" id="CLU_140470_0_0_1"/>
    <dbReference type="OrthoDB" id="10006997at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="17984" checksum="8E17F39793FBCD03" modified="2014-05-14" version="1">MSSGSTERQTINLPGTTDQPKTEPDYFLDARSTEALSQLQDGDLLKMVVDHEEDLIEFSDHVRQVAPDNVAEYFDAPGIKKFAFYRHPGSGAVILIWTRFPATASTKNARVQHRLRRDLTWHTEKADIKNVATLEVQSRKDVTAERLREAADSLKTSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQT7</accession>
    <name>X0BQT7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">beta-glucosidase</fullName>
            <ecNumber evidence="4 11">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_14699</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4 11"/>
    <dbReference type="EMBL" id="JH658435">
        <property type="protein sequence ID" value="EXK80844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQT7"/>
    <dbReference type="eggNOG" id="ENOG502SMPY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_4_0_1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000006">
        <property type="entry name" value="Beta-glucosidase H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000495">
        <property type="entry name" value="Periplasmic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF13">
        <property type="entry name" value="BETA-GLUCOSIDASE K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="12">
        <location>
            <begin position="408"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK80844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="840" mass="91979" checksum="3549B9A931E32ED9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRA4</accession>
    <name>X0BRA4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_11210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRA4"/>
    <dbReference type="eggNOG" id="KOG0022">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_14_1_1"/>
    <dbReference type="OrthoDB" id="1560166at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08278">
        <property type="entry name" value="benzyl_alcohol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000003">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350:SF11">
        <property type="entry name" value="ENOYL REDUCTASE (ER) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350">
        <property type="entry name" value="NAD-DEPENDENT ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="11"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK84685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="374" mass="39066" checksum="BA2A8DBBF242E8FE" modified="2014-05-14" version="1">MTRTTALIAPALDGSFELSEVYLDSLQPDEALIEIHASGVCHTDLSCASGKLPCAPNAVLGHEGGGVVLEIGANVTSVSPGDKVLLSFSSCGSCPGCKSDHPAYCYSFNDYNFGGKRPDGSAAMSIMKDGTKQPIYSTFFGQSSFAARTIVHQSSIVKVPQQTPLDLFAPLGCGIQTGVGAVFNTLNVRPGTSIAIFGVGSVGLAAVMAAKARETSRIIAIDLQPERLGLAKELGATDGVLGPDQEYIIKAIKNICPPLGVDFAVDCTGVPSIIETMVAALGMRGRAATVGAPGGNAHAKIDIMSHLTYGKEYVGCSEGDSNPGVLIPELIEMHAKGLLPLEKLIAYYDIKDYEKAMADMKSGKVIKPVLKWTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BST0</accession>
    <name>X0BST0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10854</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BST0"/>
    <dbReference type="eggNOG" id="ENOG502SQDV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024655_1_2_1"/>
    <dbReference type="OrthoDB" id="4216928at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="38203" checksum="0D9DD08DB0A8061C" modified="2014-05-14" version="1">MPIHEKTLKSIVKSRKLKEEGITQSLSRLVAHGVLDTRLQLFIRQVLSNDYYDGSRLPLAESDLARLNDFRVMSKPMNNALQIFNPLHLEVVRVIDQPTLHHLSDILRSFPGQFAEQGKTSFIHSALYNPSLPPPIKEVSDVCHSYHIGGEYLASSRLNALRLTIRRLLRLSKRTASFADTLAYAQAISLAQIIRLLECHDTNEDDIERDNEEMWALTHQLWQHAPTQLPSSLSPWKAWLFSENVRRTIMVCNILLVVYSSLKRGYTMHSLCVEALPFDVRTKLWDADSESAWEAAAWKVPGPHLVTLSQFTELQRPEVGGSRFENLLLLSFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV67</accession>
    <name>X0BV67_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV67"/>
    <dbReference type="eggNOG" id="ENOG502T9XA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1061913_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="263" mass="29596" checksum="F07B13EF4D7EAD68" modified="2014-05-14" version="1">MKPTNAILSVLASQATAQLIDIQIGDTARLDIMRQAAEAQVNGNTAKAHELMDQIRIADAAHEKSLWKTDCRVSSQFEAEIYTVQDPSRAPKEIAWAMNFLDNHWKTDDGRDLPYPGDFDRFMHPDGFRVMRTDYNNLPWAVRKYHEELVKEGKQMERKFIAEIDGSAFFAPGVVTWLAPLFAGSKVEPGKDACEDDLVDFSNWDKKKQAGDGVRYTFGYGGKVQIGNHITVELHAQRSSKEGAKKEAEETRGDEETEGTEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0BV83</accession>
    <name>X0BV83_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">FOQG_12933</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BV83"/>
    <dbReference type="eggNOG" id="KOG1065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_11_0_1"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000089">
        <property type="entry name" value="Alpha-glucosidase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1760:FF:000005">
        <property type="entry name" value="Putative alpha-glucosidase AgdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF67">
        <property type="entry name" value="ALPHA_BETA-GLUCOSIDASE AGDC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938889" evidence="16">
        <location>
            <begin position="25"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="18">
        <location>
            <begin position="193"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="17">
        <location>
            <begin position="349"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="19">
        <location>
            <begin position="822"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="524"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="604"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EXK82818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1026" mass="115430" checksum="212753129D9F9A25" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVH6</accession>
    <name>X0BVH6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVH6"/>
    <dbReference type="eggNOG" id="ENOG502RQAK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018874_0_0_1"/>
    <dbReference type="OrthoDB" id="4953021at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="695"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="736" mass="80719" checksum="191371767B0DD767" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWC4</accession>
    <name>X0BWC4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phenylacetyl-CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWC4"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_2_1"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF422">
        <property type="entry name" value="BCDNA.GH02901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="83"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="475"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="63991" checksum="2FF9A306C1D1D6B5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYX8</accession>
    <name>X0BYX8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979861">
        <property type="protein sequence ID" value="EXK75732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYX8"/>
    <dbReference type="HOGENOM" id="CLU_149467_0_0_1"/>
    <dbReference type="OrthoDB" id="5099858at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="112" mass="12861" checksum="6B8073F4377529AB" modified="2014-05-14" version="1" fragment="single">MISDNQTCAEFESATDWPHLALSVHSEEETNFDLPTEEEHVDNICAKKPKHVVLQYTTIDIETVPGSSTETIEAIEYQEKWEKDVEGWFKRSNYEPAGHTTLDSEPIFNCEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0A3</accession>
    <name>X0C0A3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase SirN-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0A3"/>
    <dbReference type="HOGENOM" id="CLU_010595_9_3_1"/>
    <dbReference type="OrthoDB" id="184880at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF105">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="33933" checksum="7C458D7309B5DEEC" modified="2014-05-14" version="1">MATEAVNQPPQTGTDSSVANGTGMDALMEDAKKRGLQEEISRLTDNHLVYTDAAGGKLSYAPVDWKKPGLRILDSATADGIWLQDLRKQAGPVADEQTYIGTDLVEDLFPKPRPHGIEFKKQSITEPWPTEWKESFDLVHQRQVLGFCGNFSLEQAVANLCALAKPGGWVELVELDCDQSLLEEGTAAHEFFRLLEQIWKIKKMGGNFGPNLKEWMENAGLEDVQVDVLQCKVGAKAKPELKQASINGAAGAGPMIVAMARTLPELEGFTTEQLDTLDTRVRKELAEKGAEFQSFAVRGRVPAGGLTPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C196</accession>
    <name>X0C196_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08779</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C196"/>
    <dbReference type="eggNOG" id="KOG1212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_9_1_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF2">
        <property type="entry name" value="AMIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="370" mass="41139" checksum="98B8A92EA2405116" modified="2014-05-14" version="1">MWAETDNPLWGLTENPIIPGYTPGGSSGGESALIYSHGSLGGFGSDLGGSIRMPASMMGLYGFKPSSSRLPYGGVPVSTDGQEHVPSSIGPLARSLSTIYHLTKEITLQEPWKQDCRCVPIPWRQSQYDMTVNSKLTIGVLYDDGVVKPHPSIVRVIAQAAAALAADGHELVMWKPDLHTECIEVMDAYFTVDGGEDIRRDVEAGGEPFIPSVERLVNKGKPISVFDYWQLNKRKRELQQAYLEKWNNTLSKKGKAVDAIIMPALPHAAVPHNTVKWVGYTKVWNLLDYTALVIPGGKVEAKDLDALWDHEPRNELDEWNTRLWEDNMQEMVKHHLPVDIQIVGRVLEEEKVLAVGKVLDDLLRTRLLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C347</accession>
    <name>X0C347_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10853</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C347"/>
    <dbReference type="eggNOG" id="ENOG502RVWP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044876_3_3_1"/>
    <dbReference type="OrthoDB" id="9984533at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="304" mass="33337" checksum="88CA049C874AE58D" modified="2014-05-14" version="1">MSAEIKNVMVLGGRGNLGPYLIRALVKAGFNVSVLSRTSSNVTDSTFLDAAIVKSDYTFSSLVDVFTGQDAVISTLSTANIAEQKIVIDAVAAAKVKRFMPSEFGSDTSVDGLEKMAPFLKGKQDVMDYVKSKETDGLSWTAIFTGPWIDWMLVEGKGLLCLDLRTKTGELVDSGKPKFTTTTASQVGEATAAALLHSEETKNEYVHVASYHTSQNQVIEALERISGTKFQLENLDNKDLYARATKHIEEGNWGRGYYELATATVYSDAPVTYFPDEAAHWMKVLGLVQDETFDEMITRVLKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3G1</accession>
    <name>X0C3G1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_17967</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Efflux pump involved in export of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties. Constitutes a self-protecting mechanism of the fungus against critical levels of FSA within the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658623">
        <property type="protein sequence ID" value="EXK77317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3G1"/>
    <dbReference type="HOGENOM" id="CLU_008455_11_4_1"/>
    <dbReference type="OrthoDB" id="9986881at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF59">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10370)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="41"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00054466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK77317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="482" mass="53503" checksum="B29A97B8BFD20B5B" modified="2014-05-14" version="1">MASDREDQKPAIDDQYRDHLVTFNGPDDPYNPMNWSFRKKFITAISYGLTTCWITLASAIFAAAIEPVSAEFNVNTETSAAATSLLVFGFGLGPLVWGPLSELYGRKWLILIPYFIAAIFSFSTATAKDIQTVLITRFFSGLFGSAPVTITGGVMADIWAPHQLGNAIVAYGVTIVGGPTLGPIIGGALCSSRLGWRWTEYLTGIVMMAQLAVDLLVIDESYAPILLARKAHRLRLQTQDWALHAKHEEWDVSFKELFQKYFVRPFQMMATPICLLMSLYASFVYGILYANLESFSIEYQEVRQWGPVVGTLPFIALLIGILCAAAVNIYNNRYYRRKLMENGYRAVPEARLPPMMLGGIVFTAGQFLFAWTSSPSVNYWPSIIGIALTGLGFTTIFQAALGYLIDTFTRYSASAVAANTFMRSMFSGAFPLFIIPMYHKLGVDWGTTVFGCIAAALIPVPYLFFVWGKRIRGKGKWSKDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C558</accession>
    <name>X0C558_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase type 12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658563">
        <property type="protein sequence ID" value="EXK77892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C558"/>
    <dbReference type="eggNOG" id="ENOG502SCNJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_508092_0_0_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050444">
        <property type="entry name" value="Polyketide_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45681:SF6">
        <property type="entry name" value="POLYKETIDE SYNTHASE 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45681">
        <property type="entry name" value="POLYKETIDE SYNTHASE 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 12" evidence="2">
        <location>
            <begin position="194"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="536" mass="59836" checksum="B4E9848ED5B4983C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5K7</accession>
    <name>X0C5K7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658550">
        <property type="protein sequence ID" value="EXK78037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5K7"/>
    <dbReference type="HOGENOM" id="CLU_003093_2_1_1"/>
    <dbReference type="OrthoDB" id="5097021at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1065" mass="122309" checksum="79300C53661113FC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6A6</accession>
    <name>X0C6A6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hsp70 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658532">
        <property type="protein sequence ID" value="EXK78262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6A6"/>
    <dbReference type="eggNOG" id="KOG0101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009958_6_5_1"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF81">
        <property type="entry name" value="HSP70 FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14040)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="67889" checksum="FFB442E3B97D5B55" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6A9</accession>
    <name>X0C6A9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6A9"/>
    <dbReference type="eggNOG" id="KOG4018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084528_0_1_1"/>
    <dbReference type="OrthoDB" id="277175at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000075">
        <property type="entry name" value="RWD domain-containing protein (Gir2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040213">
        <property type="entry name" value="GIR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12292">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="2">
        <location>
            <begin position="8"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="227" mass="25901" checksum="F5C330A88C24B783" modified="2014-05-14" version="1">MGREDQIEEREVLESIFPDEITDISETEFRVSVALDIPGEEDQDPPTILLQVRYPEDYPEKPPHLDILAPPNATPHEHFNIAEDRDQLLASLDDTIQENLGMAMVFAIVSTLKDNAEQLVQERKDVITKAHEEAALAAEAEENKKFHGTAVTPETFLKWREGFLKEMEEKRQQEEDERLAELKKAKTKEPARMTGRQLWERGLAGKGEEEEDDMPVEGIEKLKVEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6H5</accession>
    <name>X0C6H5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6H5"/>
    <dbReference type="HOGENOM" id="CLU_2483425_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK86414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="87" mass="9907" checksum="6DC90732638491B1" modified="2014-05-14" version="1">MGGDLDRWRHDAVKVNHAYDLECLIRQELVGPEITIHKVEGTLAGIGFAVRGYKMSEENRVCKRRSCLEIERCGMYADLESVVERSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8K7</accession>
    <name>X0C8K7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502SJCA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001305_0_3_1"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1342" mass="149641" checksum="81F831F9CBE15D8F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB62</accession>
    <name>X0CB62_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Actin-related protein 2/3 complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_08502</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Cytoskeleton</location>
            <location evidence="7">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the WD repeat ARPC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB62"/>
    <dbReference type="eggNOG" id="KOG1523">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034396_1_0_1"/>
    <dbReference type="OrthoDB" id="406844at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000220">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017383">
        <property type="entry name" value="ARPC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709:SF2">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038093">
        <property type="entry name" value="ARP2/3_su1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK88079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="363" mass="39742" checksum="7EA001117528DAE1" modified="2014-05-14" version="1">MAAPEVHHLFHHPIADHSFSADHSVLAVARDTAVELYGKVGNAFKLKDELKGHDKTVTSVDIAPNSGRIVTCSQDRNALVWEPSPTGYKPTLVLLRISRAATFVRWSPSENKFAVGSGDRVIAVCYFEEENDWWVSKHLKKPIRSTITSVAWHPNSVLLAAGSTDAHARVFSAFIKGMDSRPPPGVWGERLPFNTVCGEFLNNSAGWVHSVSFSPSGDSLAFAAHDSSITVVYPSGPEQPPRAVVTVSTQQLPFKSLIWTSEDEIIAAGYDCEAFRFQGGEAGWQLAGAIEQKGRPGLGEHREESALNMFRQMDLKGKAKDDTQLKTIHQNTISTVRPFETSGDRVTKFSTSGVDGRVVVWST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBB4</accession>
    <name>X0CBB4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658453">
        <property type="protein sequence ID" value="EXK79977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBB4"/>
    <dbReference type="eggNOG" id="ENOG502SJIZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028537_0_0_1"/>
    <dbReference type="OrthoDB" id="5348845at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="662" mass="72581" checksum="791BD95B9A912956" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD98</accession>
    <name>X0CD98_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein transport protein SFT2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_07867</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Golgi apparatus membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD98"/>
    <dbReference type="HOGENOM" id="CLU_1038438_0_0_1"/>
    <dbReference type="OrthoDB" id="660759at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF36">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SFT2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK89168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="268" mass="29959" checksum="6AC8B6642C1202DE" modified="2014-05-14" version="1">MASSSFRDSINSLGWSRRDEPVNTSHQSGLLSSLQSLNPFQGGSGYVRLPTTESSGAPLPAPSRREEEEGWFVLSRWDRLLIFGACNLAAVACFVICFTLFPVLSLRPRKFVILWSVGSLMFLASFAAVMGPMNYVYHLLSTPRLPFTAAYFGSITLTLVFALKVRSSLRWAEDFTYIPKASQHNSHLILRSCSTCLPALVLDQLFPYGIYWTALCHIVWCKASNSMDDWLEKSLDYMQYGTLVLNTFHDVPRLQGSKSSCTPTVCLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDK3</accession>
    <name>X0CDK3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDK3"/>
    <dbReference type="eggNOG" id="ENOG502RYPD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048444_1_0_1"/>
    <dbReference type="OrthoDB" id="2152248at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47381">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47381:SF3">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="36457" checksum="F0C11F51EB8B7772" modified="2014-05-14" version="1">MSINYVTQGLPAAPEISIKTVHMAGLRVDVYGLDELPPNVPVSCLWLLHPRTRSRETMNDIARRTIGAWGAHAGSNSKRGLIALAFDMPNHGTRRVSISANHPWSRGNPTHALDMFAMVKGGVLDMSGLMDLVSGYLGLEIDGHVCLGWSLGGHGAWQAFFGEKRIDAAVVIIGCPDFTGLMSGRAAGSKLDCGADFIGSKYFPKDLIEICSKHDPKAICFGTAPIPSSLSSAEQTRLRAILDERVKGKKLLLCSGGDDELVPYANTKEFSTLLKEAVGEKGWYRDGGLEVDDRVYEGIGHKFSPKMVEDAVQFLVNAVEKGPRGKAHVREGEKSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE89</accession>
    <name>X0CE89_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Agglutinin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE89"/>
    <dbReference type="eggNOG" id="ENOG502S7VC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5414836at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38122">
        <property type="entry name" value="GLYCOPROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38122:SF1">
        <property type="entry name" value="GLYCOPROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738246" description="Agglutinin-like protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="825"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="834"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="901"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="947"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1042"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1118" mass="116459" checksum="68943D3676D7F4CF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEZ9</accession>
    <name>X0CEZ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PKR1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEZ9"/>
    <dbReference type="eggNOG" id="ENOG502S6V3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068499_0_0_1"/>
    <dbReference type="OrthoDB" id="9626941at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013945">
        <property type="entry name" value="Pkr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251:SF1">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08636">
        <property type="entry name" value="Pkr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="18131" checksum="2FB0E409FFC0B5AB" modified="2014-05-14" version="1">MSSFIVKLWEDIFTPGPTPTILKAANASFAALQTVLFCLLLATYNIHCVILSILCGGLWWSVNWFAAELAIAQREQREKEEKEKQQQKEASGNDGEDSETEVETTVPSKPSPVVATTSDVAVAAAGVEPLQTKGEVKQRSGAAGTQSSVSTEDEWEKVSEAENEKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CH95</accession>
    <name>X0CH95_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_04827</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CH95"/>
    <dbReference type="SMR" id="X0CH95"/>
    <dbReference type="eggNOG" id="ENOG502QXN4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029718_0_2_1"/>
    <dbReference type="OrthoDB" id="5823761at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF1">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937663" description="cellulase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="8">
        <location>
            <begin position="39"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK93566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="333" mass="36321" checksum="F8329F601EA1C9BF" modified="2014-05-14" version="1">MRFTDFLLASAGASLALAAPHTTRAKGKFLFTGSNESGGEFGEGNLPGTLNKDYIWPTTSSIDTLASTGMNTFRVGFRMERVTPSGITGAIDEAYFKGLQDTVNHITSKGHYAVIDPHNYGRFNGNIIKSSDFSVWWQKVAKRFANNKLVIFDTNNEYHDMDNSVVAALNQAAVDAIRKAGATSQYIFVEGNAYTGAWSWVSSGNGAAMKDLKDPQNKIIYEMHQYLDSDSSGTSETCVSSTIGAERLKAATQWLKANKKKGILGETAGGANAQCIAALKGELQHLLDNSDVWTGWLYWAAGPWWGDYMFSMEPTTGTAYKKVLPQIKQFIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHS3</accession>
    <name>X0CHS3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_04209</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK93980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHS3"/>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009725">
        <property type="entry name" value="PRK13252.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK93980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="509" mass="54305" checksum="6DDBA8D7551F712A" modified="2014-05-14" version="1">MTFSSEIHTFHSGRPQPESSSKTNTFVSVDPSNAKPLATIYTTTPEQLNSAIAAAQAAFPTWSQTPAPRRAAILLKAAAILRERNDELALTETLDTGKPWSETSTVDVATGADVLEYYAHIAAGSFPGQNTRLRADAFVLTTHEPLGVCAGIGAWNYPIQIALWKSAPCLAAGNCMVYKPSEVTPLHAQTLAQIYIEAGVPPGVFNVVYGDGIAVGAPLVAHSNIAKVSFTGQVSTGSKVASQAVKDMKGVTMELGGKSPLVILPNADIEEAADTAMVANFFSTGQVCTNGTRVFVPDTLLSQVEQAIVQRCREGIRMGLPQNGETNFGPMVSAAQQEKVKMYIQHGRTVDKAKVLFDGSEEPSMAQPTSDGFWVHPVVFTNCTDNMRVVKEEIFGPVMCIMPYSTQGRTQQEWVSELIARANDTPMGLAAGVVSSDVGLAHEVVQKLDAGITWINTWGESPAEMPVGGWKMSGIGLENGHEGIAAYMRTRSTLVQLGKGACKGVFSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIH7</accession>
    <name>X0CIH7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658414">
        <property type="protein sequence ID" value="EXK82382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIH7"/>
    <dbReference type="eggNOG" id="ENOG502QSRP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027977_2_0_1"/>
    <dbReference type="OrthoDB" id="5135119at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000064">
        <property type="entry name" value="Probable acid phosphatase Pho610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF15">
        <property type="entry name" value="ACID PHOSPHATASE PHOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936427" description="Acid phosphatase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="48276" checksum="C1879F0CEDB9A7F1" modified="2014-05-14" version="1">MLFQTATILAVAGLALGHSYEPPKEHKHETGWETSYTATGTAEVAAAAATAKTSSPTSKVKGKAFDRIAIIYFENENYEKAFGDPNFTWLRKKGITLENYFGVTHPSEPNYMAAIAGDYFGMQNDDFNRNPRNVSTVIDLLEHRGISWGLYQEDMPYSGFEGFSWVNHQNGKNDYVRKHNPAVLHDSIATSEQRLSQIKNLSLVDTEKSVFHKDLKENKLPQWMFITPNMTSDGHDTSVTVAGQWARTFLEPLLKDKHFMQNTLVLVTWDENETYARQNHILGILLGDAVPKHLVGTSDNSFYNHYSEIATVSANWGLDTLGRWDVGANVFKVVAQKTGDKIRKWKSHKLDSYFWNASYAGPFNTNGGNKEYVAPNLDLEHSFSGRKIFEPIRKEWKKSKNPTYYKDTIEVNDGLNPPKGYEPAKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIR7</accession>
    <name>X0CIR7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endo-1,5-alpha-L-arabinanase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_13190</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIR7"/>
    <dbReference type="HOGENOM" id="CLU_009397_8_0_1"/>
    <dbReference type="OrthoDB" id="3879658at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08999">
        <property type="entry name" value="GH43_ABN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939436" description="Endo-1,5-alpha-L-arabinanase A" evidence="9">
        <location>
            <begin position="21"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="7">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK82477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="331" mass="35860" checksum="744E2F8682C8FCD9" modified="2014-05-14" version="1">MITQGLVWPVLGLLFNPVSAGTIRQSALKLTVKHEGTLNPAINADFPDPSIIQLEDGSWVAVATNGGPPDNYRKLQVATAKDLLGEWTLKQEDALPDKGWTTGENTWAPDIRRVDSGEYIVYLSPEIETGRHCIGVARSKNATGPYTYDEKPLVCGPDDLKGAIDASGFKDPDSGKNYLIYKIEGDASGPTGGTPIMLQEIEGDGITFIGDAVKIFDRIGSEDGVLVEAPNIVRLGNGKYVLFFSSHDFRDPLYNVKYAYADKLSGPYTRADEPLIAAPDFGLDAPGGATSNEAGDTLVFHGWCPDDKNIRYLFIDLSFEIVGQSDPLFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CK69</accession>
    <name>X0CK69_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CK69"/>
    <dbReference type="eggNOG" id="ENOG502SWGH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042308_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="379" mass="40917" checksum="7F673CB6E9C80C92" modified="2014-05-14" version="1">MASQSHQEPDPLDVLQNMVNDVLVHTGKALRASRKDAQGSTQSTQSTLKSKLPESIDGFREALHKLEWDIIDAKSVLMRDIKRLQEQKQQQSQQIQQSQPTPVSQPPRPQPVESQSKSPMVIDLESSPPPPPQDQHMTEIKTNKPVAPFPDMGMGLPDVGQPISVPNDETSSSVIPSTGPEQPITKTISPAAPASAPAATAPMAPMPIMEQKPVDNQNNDVTDLTGDGPHSELNFTNMQFTLAPTNNDSQNPSNSQDPSFDLATFAPPEGNDDILGLDDILPTNNTSQTNGISQLPAGSADNASKQDLPMDTDNLGASQEMSTNNYDSVFDDEIFGGLGTGDGLADGTDDITFESLMNDRDDDNLNYGEFDDTFLLENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKJ7</accession>
    <name>X0CKJ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_03714</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TALE/TGIF homeobox family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKJ7"/>
    <dbReference type="eggNOG" id="KOG0773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055480_0_0_1"/>
    <dbReference type="OrthoDB" id="10056939at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000059">
        <property type="entry name" value="TGFB-induced factor homeobox 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="303"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="8">
        <location>
            <begin position="305"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="392"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="393"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK94965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="436" mass="48562" checksum="246705FF12694F0C" modified="2014-05-14" version="1">MEDSRSLSKQSETKPRTSAPQLPNMSMLATASPSPHPSSFGMPRPWETNRCPDYSLRPRTENDKVALPSIRQAFPELQLHTQPPHDLNTKPPSTGPPLGAPPLTAASPQYIHSPNSSKRRRLSMEREVETERVRQVPRLCYSPDRASPRQISPHLPIQGGSQENWAAPTRTSPFLTNGSNSHSVPMEASERAESRSTLPSLPPPRSLERELPVGRGTAPSDGYRPPQQSMSHSRTPISEPGVSPYRENGYGYPYHHPTRYQSLSTGSAHSYDRTPFTPGTYNTPYQDFVRFGDMSSASLSGDNKQRKRRGNLPKETTDKLRAWFVAHLQHPYPTEDEKQDLMRQTGLQMNQISNWFINARRRQLPAMINNARAETDAMTGARGGDLKVLATTERGDFDHSKREPAGPLSDGEGATYDEELEALSQRRPGTIGRGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CL49</accession>
    <name>X0CL49_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_03678</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CL49"/>
    <dbReference type="SMR" id="X0CL49"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017390_0_0_1"/>
    <dbReference type="OrthoDB" id="6407164at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051252">
        <property type="term" value="P:regulation of RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12520">
        <property type="entry name" value="RRM1_MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12521">
        <property type="entry name" value="RRM3_MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12522">
        <property type="entry name" value="RRM4_MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000047">
        <property type="entry name" value="Differentiation 1 negative regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000064">
        <property type="entry name" value="Differentiation 1 negative regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000130">
        <property type="entry name" value="Differentiation 1 negative regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000120">
        <property type="entry name" value="Negative regulator of differentiation 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034195">
        <property type="entry name" value="Mrn1_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018835">
        <property type="entry name" value="RNA-binding_domain_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF8">
        <property type="entry name" value="RNA-BINDING PROTEIN MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10378">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="194"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="285"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="419"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="510"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="118"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="577"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="586"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK94901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="786" mass="83659" checksum="1DBAE04EE9A6C0C1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM00</accession>
    <name>X0CM00_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GPI inositol-deacylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_04038</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CM00"/>
    <dbReference type="HOGENOM" id="CLU_165621_0_0_1"/>
    <dbReference type="OrthoDB" id="427518at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="14361" checksum="CB452B08B5E8931E" modified="2014-05-14" version="1">MSFVYDSTIIHSDSADVTQGSLDYEARSLCSFVEEQRLSTDSSSRPIILVAHSLGGLVCATPIILGDRNAQGDDVEAVARDVAGMVFLGTPFTSSNAAKWGELVRKIFNVVKKTDQNTLKTLKENSHDLQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM78</accession>
    <name>X0CM78_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Cellulase</fullName>
            <ecNumber evidence="3 10">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_05937</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 45 (cellulase K) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3 10"/>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CM78"/>
    <dbReference type="SMR" id="X0CM78"/>
    <dbReference type="eggNOG" id="ENOG502QTGS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10035502at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22278">
        <property type="entry name" value="DPBB_GH45_endoglucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052288">
        <property type="entry name" value="GH45_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000334">
        <property type="entry name" value="Glyco_hydro_45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730:SF1">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02015">
        <property type="entry name" value="Glyco_hydro_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01140">
        <property type="entry name" value="GLYCOSYL_HYDROL_F45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937294" description="Cellulase" evidence="12">
        <location>
            <begin position="25"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="13">
        <location>
            <begin position="381"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="273"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK91934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="422" mass="44493" checksum="94A589ECB7144FE3" modified="2014-05-14" version="1">MRCASRYSGCWTLLHCLLIHSLHSFFRITYTLFQNSHSLNKPTFATMRSYTLLALAGPLAVSAASGSGHSTRYWDCCKPSCSWSGKAAVNAPALTCDKNDNPISNTNAVNGCEGGGSAYACTNYSPWAVNDELAYGFAATKISGGSEASWCCACYALTFTSGPVKGKKMIVQSTNTGGDLGDNHFDLMMPGGGVGIFDGCTSEFGKALGGAQYGGISSRSECDSFPELLKDGCHWRFDWFENADNPDFTFEQVQCPKALLDISGCKRDDDSSFPAYKGDTSASKPQPSSSAKKTTSAAAAAQPQKTKDSAPVVQKSSTKAAAQPEPTKPAEKPSAAKPAATKPAATKPAQPVNKPKTTQKVRGTKTRGSCPAKTDPTAKASVVPAYYQCGGSKSAYPNGNLACATGSKCVKQNEYYSQCIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CME0</accession>
    <name>X0CME0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sphinganine-1-phosphate aldolase</fullName>
            <ecNumber evidence="14">4.1.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Sphingosine-1-phosphate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_12034</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 16 17">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.27" evidence="14"/>
    <dbReference type="EMBL" id="KI979328">
        <property type="protein sequence ID" value="EXK83672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CME0"/>
    <dbReference type="eggNOG" id="KOG1383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028929_1_0_1"/>
    <dbReference type="OrthoDB" id="10254570at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008117">
        <property type="term" value="F:sphinganine-1-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030149">
        <property type="term" value="P:sphingolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.140.2150:FF:000002">
        <property type="entry name" value="Sphinganine-1-phosphate aldolase Bst1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000020">
        <property type="entry name" value="sphingosine-1-phosphate lyase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050477">
        <property type="entry name" value="GrpII_AminoAcid_Decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735:SF6">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE LYASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 16 17" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="16">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00042568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK83672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="571" mass="62716" checksum="88A0E281A7496DFC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMR8</accession>
    <name>X0CMR8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMR8"/>
    <dbReference type="eggNOG" id="ENOG502R0V8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_499695_0_0_1"/>
    <dbReference type="OrthoDB" id="5055285at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="557" mass="61849" checksum="BC1281FB70094110" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNE8</accession>
    <name>X0CNE8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleolar GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_05834</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNE8"/>
    <dbReference type="eggNOG" id="KOG1490">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011784_4_1_1"/>
    <dbReference type="OrthoDB" id="415015at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000496">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024926">
        <property type="entry name" value="NOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038919">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="10">
        <location>
            <begin position="168"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="542"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="452"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="390"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK92818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="659" mass="75521" checksum="ED26430A02A16F86" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP38</accession>
    <name>X0CP38_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP38"/>
    <dbReference type="HOGENOM" id="CLU_1555316_0_0_1"/>
    <dbReference type="OrthoDB" id="3535423at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="151" mass="16510" checksum="24D4C10AB5B959B2" modified="2014-05-14" version="1">MANSPIIQSTLSVVSGQLCFGSLHNIWFGSSAPSQGLPVAPPHQVAQLKLTASTTTLPHKKEYGTPSNLQEVDKILRISVSPYEPDHGSTINNDVTSQAGVFVVNRYDWGYYDKRCFDEIGEGQEEDDDDVLANSNSLGLVDRSIVQEMVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP84</accession>
    <name>X0CP84_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05715</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP84"/>
    <dbReference type="eggNOG" id="KOG3105">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040209_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041188">
        <property type="entry name" value="HTH_ABP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18107">
        <property type="entry name" value="HTH_ABP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="111"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK92644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="401" mass="44739" checksum="F784BD697B37A8FC" modified="2014-05-14" version="1">MSAATTDPALVAAPAPDLSPVDAVAQVGHDVTSVDHVGDHVGASPKERHSLTLDQRRALRRWANSQPIRPSHKACIEWFFSQYGQQISQSTVSHSLSPKYSRLDSDNPQLSGSRLRYGNWPDVEKLVLIWYQQVQASGRQPTNEELGDKAKSIFGQLPRYKDENPPEFSPGWIHRFKKRYGLLIRRQRRHGDGGINAAEDIGYLADCVPRYMSVAPDTSPAAIKEEIIRAVGIEPTLNTCALVRDEVVRRMTGPPQQVPPPPPLMMTHDPPAIPPPQPDQPIYADDDPEVVLQNALRQLQQEEQAAEEQAAAVREERERAERAGLQPNSILTTPTVRATSVQRYTATPAHDMTTDLTLTPITSEQPMTRDDRPVRCPFCVNQRMLRSIKEAVEHLSTHVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPM1</accession>
    <name>X0CPM1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleolar protein 58</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_05393</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for pre-18S rRNA processing. May bind microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPM1"/>
    <dbReference type="eggNOG" id="KOG2572">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015495_5_0_1"/>
    <dbReference type="OrthoDB" id="6780543at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000003">
        <property type="entry name" value="Nucleolar protein 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000001">
        <property type="entry name" value="Probable Nucleolar protein 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Nop" evidence="10">
        <location>
            <begin position="285"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="443"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="517"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="471"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="581"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK93243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="593" mass="65271" checksum="43563F71077820F2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPQ0</accession>
    <name>X0CPQ0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WW domain-containing oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPQ0"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083410_0_0_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF152">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="31783" checksum="540327AB9F0F09C2" modified="2014-05-14" version="1">MTSLAKTIVATGVSSGIGFEAIKQLLSQSQPYKVILGARNTKNAQKAYDELKFDRESHGVTVLPLELNDLKGVKSFAEQTLDKIGREKIDYLLLNAGLGGVAAEGPGPHGSKWCEPHVVNHLSQHYLVHLLREKLVESKSRIVFVSSGAIRRVSDPSVLDTELKAGSGASASTTYCNTKFTGLLGAQWWRRQLADTNDVVAVSPGLIPGTGLAGRMGITADMADAKSIPEGAQSVLAAMTRSDFPEDRDRIFLTSWGEWWEKSVIEKSTDKELQDKWCPSKEEIEREAGISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPS9</accession>
    <name>X0CPS9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein RTA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_11326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658395">
        <property type="protein sequence ID" value="EXK84537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPS9"/>
    <dbReference type="eggNOG" id="ENOG502QURG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033465_5_1_1"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK84537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="16616" checksum="18D1F777F002E1C6" modified="2014-05-14" version="1">MDFLSLAGGGMMAGGSLEALHNGERIVIIGLIVQIVFFSLFAVTAAVFHMRLVGSMSAKAAVSGIPWQRYLYTLYIASGLILVRSVFRLIEYAQGNAGYLISHEAYLYIFDSVLMFLAMVLFVFEHPSQLNAKLNGGGTAVRNGIRLYWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQF2</accession>
    <name>X0CQF2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQF2"/>
    <dbReference type="eggNOG" id="ENOG502RJ5B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2386329_0_0_1"/>
    <dbReference type="OrthoDB" id="4874932at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936552" evidence="1">
        <location>
            <begin position="19"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="108" mass="11137" checksum="51EB13AA42B5B448" modified="2014-05-14" version="1">MQFTSLLSVATFAAAAMAASVQVNFYSDTGCQNFIGSRFIDFDPSRGGTHHSGGPAGSRGGLFVNSNGDNLAFRGFSNHPDGSSPFTGNVVDGECIVTLNGVVAVFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQJ7</accession>
    <name>X0CQJ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GS catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11294</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQJ7"/>
    <dbReference type="eggNOG" id="KOG0683">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017290_6_1_1"/>
    <dbReference type="OrthoDB" id="3364440at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF2">
        <property type="entry name" value="TYPE-1 GLUTAMINE SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="4">
        <location>
            <begin position="125"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="448" mass="49460" checksum="AE9942AA3D1A4E85" modified="2014-05-14" version="1">MSTSIHEETHANRAAGSVEEFFNQNHSVQVVILQWVDICGIIRTRLLPASRFRNLVRSGGHLDCAPLDTLVPTTAEFIPQLFALFNGKGQIYPDVSSIRTMKHDASGIGNAARCVGTVDFQNTDARLLLDDIDKKAGESRGLKFLVGIELEFCLLVPGTLEAAEPAKPGVAGTLGTLRSKVWPILNEIIVAFGEAGIEVQQVIKEYGTSAYEVALPPLPPIEAVDTYYYAKELIQNVAHKYGILATFYPTPYDGEQGQKSGQHIHISATQTEENKDWNPDDTLAGILSHIPALMALGMCQVDSYERVNIGRMCTGGLVGWGDNNRDMPVRRVTKNHWEIRVNDATSNSYAMVAAIIGAALDSKPLTIANAAEFTLMYSDEERVKMGLTKLLPTSLEAALTELEDDRAWADSVLGQEYIDWFLALKRAEMNTVSKMETKERRLHMLSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQP1</accession>
    <name>X0CQP1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ubiquitin conjugation factor E4 B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_04901</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQP1"/>
    <dbReference type="eggNOG" id="KOG2042">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="20295at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034450">
        <property type="term" value="F:ubiquitin-ubiquitin ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000055">
        <property type="entry name" value="Ubiquitin conjugation factor e4 a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019474">
        <property type="entry name" value="Ub_conjug_fac_E4_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045132">
        <property type="entry name" value="UBE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931:SF2">
        <property type="entry name" value="UBIQUITIN CONJUGATION FACTOR E4 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931">
        <property type="entry name" value="UBIQUITINATION FACTOR E4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10408">
        <property type="entry name" value="Ufd2P_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="13">
        <location>
            <begin position="1011"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="545"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK93653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1099" mass="124817" checksum="B684E2DF25D2BF16" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRT1</accession>
    <name>X0CRT1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Neutral ceramidase</fullName>
            <ecNumber evidence="4">3.5.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_10836</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid</text>
            <dbReference type="Rhea" id="RHEA:20856"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="ChEBI" id="CHEBI:57756"/>
            <dbReference type="EC" id="3.5.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the neutral ceramidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.23" evidence="4"/>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRT1"/>
    <dbReference type="eggNOG" id="KOG2232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011300_0_1_1"/>
    <dbReference type="OrthoDB" id="191371at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017040">
        <property type="term" value="F:N-acylsphingosine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.2300:FF:000004">
        <property type="entry name" value="Neutral/alkaline nonlysosomal ceramidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2300">
        <property type="entry name" value="Neutral/alkaline non-lysosomal ceramidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006823">
        <property type="entry name" value="Ceramidase_alk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038445">
        <property type="entry name" value="NCDase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031331">
        <property type="entry name" value="NEUT/ALK_ceramidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031329">
        <property type="entry name" value="NEUT/ALK_ceramidase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670">
        <property type="entry name" value="CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670:SF1">
        <property type="entry name" value="NEUTRAL CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04734">
        <property type="entry name" value="Ceramidase_alk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17048">
        <property type="entry name" value="Ceramidse_alk_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939564" description="Neutral ceramidase" evidence="5">
        <location>
            <begin position="31"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase N-terminal" evidence="6">
        <location>
            <begin position="54"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase C-terminal" evidence="7">
        <location>
            <begin position="584"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="506"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="547"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK85182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="748" mass="81337" checksum="B0C39A970F875C7F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS96</accession>
    <name>X0CS96_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_02560</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS96"/>
    <dbReference type="eggNOG" id="KOG0257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2108at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050596">
        <property type="entry name" value="AspAT/PAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="107"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK97320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="467" mass="52596" checksum="7DB73E304B08B2F7" modified="2014-05-14" version="1">MSFSGRKFSINRHTGAPKTLTRRFSTTEPSMNEFQSKVHRQFRSAHEGHMPHAGLDASRSSTGVIWCTERASEYGYLENPDAWANLGQGAPEVEDDIEGCFPRPETINISMAGREYGPTAGIKPLREAVAKLYNEAHRQGKESQYTWENVAIVPGGRAGLIRIAAVLGNSYLSFFLPDYTAYNEMLSLFKNFAAIPVPLAEEDGYHIHPDKIAEEIARGTSVILTSNPRNPTGRVIANPELAEIQDICRDRATFISDEFYSGYNYTSNCDGSTISAAENVDDVDEDDVLIIDGLTKRFRLPGWRIAWILGPKEYINAIGSCGSYLDGGACHPFQEAAIPMLEPSVVKNEMIHLQSHFRDKRDFVVRRLREMGFIIKYVPDSTFYLWLNLEGLPESISDGLNFFQACLEEKVIVVPGIFFDLNPSRRRDLFDSPCHHFVRLSYGPRMDVLKMGMDAIERVVQKHRKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSU3</accession>
    <name>X0CSU3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSU3"/>
    <dbReference type="HOGENOM" id="CLU_091801_0_0_1"/>
    <dbReference type="OrthoDB" id="2740448at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="171" mass="18897" checksum="4448ED5911CDB5F5" modified="2014-05-14" version="1">MGKKKSKNNSTEAASRAPANALTTTSTIVADPKLGYRIRVLLHDFLNVAKDSRSEKRLNSTIDEHYISAPYFDEGQATMVKAAIIDVDLVKHAEATDTEDIDRYLVSQQGMSFETAVRTLLGSFLDKRRASGDARPCGPHHLAPLYAKFFGIDLEELKEDKFLGGLRRAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT46</accession>
    <name>X0CT46_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="16">ATP-PFK</shortName>
            <shortName evidence="16">Phosphofructokinase</shortName>
            <ecNumber evidence="16">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">FOQG_04545</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">54005</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 16">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="16">Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 16 17">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 16">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Mitochondrion outer membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="16"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT46"/>
    <dbReference type="eggNOG" id="KOG2440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011053_0_0_1"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005945">
        <property type="term" value="C:6-phosphofructokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070095">
        <property type="term" value="F:fructose-6-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061621">
        <property type="term" value="P:canonical glycolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.450:FF:000010">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000007">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000008">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="entry name" value="Phosphofructokinase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03184">
        <property type="entry name" value="Phosphofructokinase_I_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009161">
        <property type="entry name" value="6-Pfructokinase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02478">
        <property type="entry name" value="6PF1K_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697:SF4">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000533">
        <property type="entry name" value="ATP_PFK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="12 16 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14 16 17" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="11 16 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="18">
        <location>
            <begin position="6"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofructokinase" evidence="18">
        <location>
            <begin position="398"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal catalytic PFK domain 1" evidence="16">
        <location>
            <begin position="1"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interdomain linker" evidence="16">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal regulatory PFK domain 2" evidence="16">
        <location>
            <begin position="398"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="77"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="107"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="16">
        <location>
            <begin position="153"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="16">
        <location>
            <begin position="197"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="16">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="16">
        <location>
            <begin position="291"/>
            <end position="294"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="16">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="16">
        <location>
            <begin position="532"/>
            <end position="536"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="570"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="16">
        <location>
            <begin position="577"/>
            <end position="579"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="16">
        <location>
            <position position="637"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="663"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="16">
        <location>
            <begin position="669"/>
            <end position="672"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="16">
        <location>
            <position position="741"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR000533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXK94493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="783" mass="85280" checksum="6122B3B866C6AFF4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT75</accession>
    <name>X0CT75_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_10459</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT75"/>
    <dbReference type="HOGENOM" id="CLU_016058_3_1_1"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK85667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="673" mass="74379" checksum="4C3C288ED7E80C40" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTF7</accession>
    <name>X0CTF7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloacid dehalogenase, type II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTF7"/>
    <dbReference type="eggNOG" id="ENOG502S0RM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_3_2_1"/>
    <dbReference type="OrthoDB" id="444127at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01493">
        <property type="entry name" value="HAD-SF-IA-v2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF9">
        <property type="entry name" value="ACID DEHALOGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="240" mass="26794" checksum="177F9E6174801233" modified="2014-05-14" version="1">MSKISDFGLLSFDVYGTLIDWETGVLNGLKPLLQSNNAEISREDLLKTYHEAEVAQQKKTPDMKYSELLTTIHPHVAERLGFSQPTSEQNKAFGDSIGSWPAFPDTVDALRRLGKHYKLVVLSNVDRESFSGSNAGPLQGIPFDLIITAQDVGSYKPNLNNFKYMLREVEAKFGIPKEKVLQTAQSQFHDHQPAKQMGIKSSWIERPGASMGNTEDPVYDWKFATLGDMADALEKEIASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUF1</accession>
    <name>X0CUF1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUF1"/>
    <dbReference type="HOGENOM" id="CLU_2158469_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="111" mass="12636" checksum="77F549CBE56182AE" modified="2014-05-14" version="1">MVSLLMQAMQQHFDKHGPHTCSWPFLLAVLSRLICFINGLLILAVAMQYANSDRDKQPTGTFSKADCYMAPFVGHSTVYHRRQAFVDQKPLYLCLILLTRSLLPARRPNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUT0</accession>
    <name>X0CUT0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUT0"/>
    <dbReference type="eggNOG" id="ENOG502T4JG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134552_0_0_1"/>
    <dbReference type="OrthoDB" id="4966225at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK97921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="139" mass="15400" checksum="A5A31C05AD3A0080" modified="2014-05-14" version="1">MSSLPKHFIIVVNGQHVTKPENDRDEIRPAQVGEKPATFELNENRLISGDWAMGCSKLEGQVPGTRTPSLAVFWFRRGQAEELYPVYLKEGDNGPQLKFACNAVDEEGRPLAVLNKQLLCYTSDNSEPGATVEIVPSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYI4</accession>
    <name>X0CYI4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYI4"/>
    <dbReference type="eggNOG" id="ENOG502T8ZK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028689_0_0_1"/>
    <dbReference type="OrthoDB" id="5107072at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="740" mass="77445" checksum="C6FCB7F17A154009" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYP4</accession>
    <name>X0CYP4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_01835</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYP4"/>
    <dbReference type="eggNOG" id="KOG3138">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054412_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="75"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="270"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK99256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="350" mass="37398" checksum="31EF4931DE81D019" modified="2014-05-14" version="1">MSLPSTKPAQTSIRSFFSAKTPKYAPPPSQGALIELSGPPPPPAATAPPPTSKTPDSTIASFQIPPLPTSLPQEATIRLVSNDDINALRRINALLLPVGYPDSFYQRAVDPTSGRFSRVITWAHDGSEAKVVGGVVCRVEPILDSNSQGVMPQNLYIQSLCLLSPYRSLGLMNAAVDNIIAGAVSDPNLNVTTVTAHVWTENEEGLKWYEGRGFKRENQPIEGYYLKLRPNSAWLVSRPTGASVRNLLPSSSSAPQHSVLASATADIANLDAASGPPRSSTSRPPMPQSGKSYQNQRPETEWNDLPEDMANSRLAPPPRVGSTGSSASSRSSSAARKKKDRSYPAAAFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0A7</accession>
    <name>X0D0A7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP citrate synthase</fullName>
            <ecNumber evidence="4">2.3.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_02355</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA</text>
            <dbReference type="Rhea" id="RHEA:21160"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.3.3.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="4"/>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0A7"/>
    <dbReference type="eggNOG" id="KOG1254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006587_3_1_1"/>
    <dbReference type="OrthoDB" id="5295093at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042709">
        <property type="term" value="C:succinate-CoA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003878">
        <property type="term" value="F:ATP citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006104">
        <property type="term" value="P:succinyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000004">
        <property type="entry name" value="ATP-citrate synthase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.110:FF:000003">
        <property type="entry name" value="ATP-citrate synthase subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032263">
        <property type="entry name" value="Citrate-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056749">
        <property type="entry name" value="Citrate_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF10">
        <property type="entry name" value="SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16114">
        <property type="entry name" value="Citrate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24948">
        <property type="entry name" value="Citrate_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-citrate synthase ATP-grasp" evidence="15">
        <location>
            <begin position="2"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-citrate synthase citrate-binding" evidence="14">
        <location>
            <begin position="298"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF24948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK96993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="489" mass="53264" checksum="F99A9861A2D96C87" modified="2014-05-14" version="1">MSAKSILEADGKAILNYHLTRAPVIKPSPLPAPTTHNPPSRLASLHFPEDANVEDILNQAEVTYPWLLQPDAKFVAKPDQLIKRRGKSGLLALNKTWPEAKAWVAERAGKEQQVEHTTGVLRQFLVEPFVPHPQDTEYYININSVRDGDWILFTHEGGVDVGDVDAKAEKLLIPVDLAEYPSNEEIAATLLKKVPQGVHNVLVDFITRLYAVYVDCQFTYLEINPLVVIPNEDKTSAAVHFLDLAAKLDQTADFECGVKWAIARSPAALGLTNIAPSADGKINIDAGPPMEFPAPFGRELTKEEAYIADLDAKTGASLKLTVLNAKGRIWTLVAGGGASVVYADAIASAGFADELANYGEYSGAPTESQTYHYARTVLDLLLRAPQSDEGKVLFIGGGIANFTNVASTFKGVIRALRDFAPKLIEHNVSIWVRRAGPNYQEGLKNMKAATQELGLNAKIFGPEMHVSGIVPLALVPGKWEESKAQEFQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0D4</accession>
    <name>X0D0D4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0D4"/>
    <dbReference type="HOGENOM" id="CLU_3384791_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL00206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="33" mass="3761" checksum="9E7189F2D9DE2EEF" modified="2014-05-14" version="1">MAIEYQLRFKELNVALQPLENGKIDVYEPGKPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0F8</accession>
    <name>X0D0F8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00487</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0F8"/>
    <dbReference type="eggNOG" id="ENOG502SPRN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036934_3_0_1"/>
    <dbReference type="OrthoDB" id="5218140at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF11">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL00241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="50336" checksum="A75DAC416F746CA3" modified="2014-05-14" version="1">MANTATADERPSFTEFLKKTKQKVAGTPCEGPDCATPQRRGRKSRGSVGVSSESPENSSETSPQKSRKSLTATEKAKLRRTQVRRAQIQHRQRKAEYQKQLELDITHFRELIALTEFESEQLKKDNDSIKELLTNKGITIPRCKSGTCSIRPRLTKDVVTGDNDAWVDDTLGVKLRAEDPSFQEYDQDGGEIFADINVDDIIVTLKKDESMETPAFSIRSNESSSNATSSPPPLPDLNLTPDEEQKAVNFILSLEHICWDHFFVGDFPSHSHLSNDEPKGHCLMASSLCMANAPLDVFGDRKLVSSASSCHNRRSLGLDPYVPPVHLEWPSPRISLSSLYGLAQSLNPGDLEITPVQAWFELASRFDKSLLLERLDLLGTELVGVSKCLEFGAVMEKDAFESVVARVYGGTLEEAMAAAAIIDPHMGSVCDISRMRNFQANLLTNQLGFVGYAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0D249</accession>
    <name>X0D249_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_08036</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D249"/>
    <dbReference type="eggNOG" id="KOG0281">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_103_0_1"/>
    <dbReference type="OrthoDB" id="19711at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="95"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="336"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="377"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="501"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="189"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="627"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="724"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="829"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="724"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="829"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK88737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="954" mass="105163" checksum="9BE875E4DE8D6C42" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2B4</accession>
    <name>X0D2B4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_00861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2B4"/>
    <dbReference type="eggNOG" id="ENOG502SI3Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014722_5_2_1"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF11">
        <property type="entry name" value="WSC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938137" description="DUF1996 domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="3">
        <location>
            <begin position="41"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="381"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXL00916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="522" mass="56716" checksum="4D58542EE2160B78" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4M7</accession>
    <name>X0D4M7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_01101</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">Cytoskeleton</location>
            <location evidence="6">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ARPC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4M7"/>
    <dbReference type="eggNOG" id="KOG1876">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084855_1_0_1"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000001">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008384">
        <property type="entry name" value="ARPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629">
        <property type="entry name" value="ARP2/3 COMPLEX 20 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05856">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039100">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR039100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK98089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="169" mass="19682" checksum="9778D501E096BDD8" modified="2014-05-14" version="1">MSQSLRPYLQCVRSSLTAALTLSNFASQTAERHNVPEIEAQTSPEVLLQPLTIARNENERVLIEPSINSVRISIKIKQADEIEHILVHKFTRFLTQRAESFFILRRKPIKGYDISFLITNFHTEEMLKHKLVDFIIQFMEEVDKEISEMKLFLNARARFVAESFLTPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4P2</accession>
    <name>X0D4P2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4P2"/>
    <dbReference type="HOGENOM" id="CLU_2996522_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="57" mass="6384" checksum="7080921B9162DDE1" modified="2014-05-14" version="1">MASACAQVQVQEYIKNEKLANTQRKHSQHPARSVNFLYRDGEAGLDWQGGRGAWAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9M9</accession>
    <name>X0D9M9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_00492</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9M9"/>
    <dbReference type="ESTHER" id="fusof-f9g6e6">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="125"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="74"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXL00249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="632" mass="70416" checksum="1C64B9663E2F0881" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9W3</accession>
    <name>X0D9W3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6594 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_00556</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9W3"/>
    <dbReference type="eggNOG" id="ENOG502RNYZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5079013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046529">
        <property type="entry name" value="DUF6594"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20237">
        <property type="entry name" value="DUF6594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6594" evidence="3">
        <location>
            <begin position="110"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXL00344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="289" mass="32248" checksum="9AA8F37EDDA857E3" modified="2014-05-14" version="1">MSRPCQMNAPEGNFVQKPASEPPRSEEAGAPSMRPGIDLERQAGSWGGERGWVRMCRQIQQDKRHMVAPRLSNISSRCIMLQANRMVTLYAEAEKAFELGKEDANSNEKFVEEYLKYSQLLLQTNQVLALDKPGSYFLRNLLPSFRAMLKGGSGNYLDAPMNDWASLSQPDRLDQLICLAAYTRVGRTLFTPFLSRQEEVDDNDQYHYNEGAIRFITITIFSSIIAVFACAPAAIQSLNVRSTVGEVVVYLVFVIVFGWLSQGLILGFEKVLLSCLAYAGLMATLLRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBC3</accession>
    <name>X0DBC3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GmrSD restriction endonucleases C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBC3"/>
    <dbReference type="HOGENOM" id="CLU_043034_3_1_1"/>
    <dbReference type="OrthoDB" id="3162605at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="GmrSD_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24094:SF15">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24094">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="GmrSD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738260" description="GmrSD restriction endonucleases C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="GmrSD restriction endonucleases C-terminal" evidence="2">
        <location>
            <begin position="88"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXL00430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="200" mass="21814" checksum="1D93910287EE8A77" modified="2014-05-14" version="1">MKFSIALLVPVAGVLAAPTPPGIPSDSTARSLLSGLTVAASTNTGTYDRDLFPHWETYEGACNTREYVLKRDGTNVVTNSACAATSGTWKSPYDGATWTQASDIDIDHMVPLKNAWISGAASWTTAKRTQFANDVTRPQLWAVTDNVNQAKSDKSPDSWKPPLTSFYCTYAKSWIQVKSYWQLTITSAEKTALGSMLDYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCA5</accession>
    <name>X0DCA5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PLD phosphodiesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_06075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCA5"/>
    <dbReference type="OrthoDB" id="47785at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
        <property type="term" value="F:3'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09122">
        <property type="entry name" value="PLDc_Tdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF4">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="26"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="467"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="548"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="467"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="550"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="614"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="3">
        <location>
            <position position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK92162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="665" mass="73330" checksum="16C87F62B096A238" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DH90</accession>
    <name>X0DH90_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DH90"/>
    <dbReference type="HOGENOM" id="CLU_2941751_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="60" mass="6360" checksum="DDE948245B7566BB" modified="2014-05-14" version="1">MAVCNLNCNLYRIVRPWNLTGSKGSRCDLFSGCALNRAVQSRGRKGSTGPIGLAGSTPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0DPJ6</accession>
    <name>X0DPJ6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03329</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DPJ6"/>
    <dbReference type="HOGENOM" id="CLU_2223359_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="106" mass="11957" checksum="14F7D9565A00A05C" modified="2014-05-14" version="1">MQAACMQNTTAFRLVHPSNQTTCFYRIFLATFAQAFRDPVNSPTSSLMAGPTGLFNFTSLRAPFTKRIIVTIPYITLSNNPFTLSLLRSSLFGRNLFHGLSRELYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0DRM8</accession>
    <name>X0DRM8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-classical export protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DRM8"/>
    <dbReference type="HOGENOM" id="CLU_2775968_0_0_1"/>
    <dbReference type="OrthoDB" id="2155101at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024242">
        <property type="entry name" value="NCE101"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11654">
        <property type="entry name" value="NCE101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7810" checksum="EFE14EA305AB4032" modified="2014-05-14" version="1">MPAPTYIISRAADPIFGVLIGLSAAATRINREEKDKGRTTQQTLEAARRIDELDFLPSLRDYVWARFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0E4S2</accession>
    <name>X0E4S2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_01037</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E4S2"/>
    <dbReference type="eggNOG" id="ENOG502RY03">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_5_2_1"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="119"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="5">
        <location>
            <begin position="460"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXL01228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="600" mass="66885" checksum="888FEB909A0B0B03" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0B156</accession>
    <name>X0B156_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_19390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="KI979769">
        <property type="protein sequence ID" value="EXK75845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B156"/>
    <dbReference type="HOGENOM" id="CLU_601343_0_0_1"/>
    <dbReference type="OrthoDB" id="5098447at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="3">
        <location>
            <begin position="355"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK75845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="455" mass="49204" checksum="24887FB0224B9B1F" modified="2014-05-14" version="1">MDLPITTAAWGEVPFESEWEPGRGWLQVLRRPGKHASVCLDGYLSKDFDQDDEESCYRRAAVQHLALFVPWESFLCREADDINSIWARAREALPPRILCLVDNVQLLRRSAEDAKRDARQWAASAGDADFTAARTGEEGEGEAGEEAASVYQSGSIGNATRLIDVVRSAVGANQITAGSPEIMATMEQLCRFQQSALSSTAELQATVMPERGERLISIPEGAFSGTVIPPQDQVKAIKSQQICASRERERMIQGLQNMAAADKTEHSAAVRSVLTGFGEEDIQMTAADLEETAAEAGPRMEVDFGASTSFLEAGKALAARFTLNRRQTIAFLIICRQLDSIQCSDRGDVGQLCEFVGGEGGTGKSRVIEALVELFASKGISNRLLITATSGTAAARINGITIHSACGFSKDQAAGANTAKDLDGVRLPKQAERFVHGQSRLVWTGRRKTCSSSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4Q3</accession>
    <name>X0B4Q3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979416">
        <property type="protein sequence ID" value="EXK77115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4Q3"/>
    <dbReference type="HOGENOM" id="CLU_095789_0_0_1"/>
    <dbReference type="OrthoDB" id="3853793at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046925">
        <property type="entry name" value="WD-like_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20493">
        <property type="entry name" value="WD-like_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936228" description="WD-like domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="WD-like" evidence="2">
        <location>
            <begin position="69"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="179" mass="19022" checksum="167734789DEAEF0A" modified="2014-05-14" version="1">MFLSKQTLFVLSSLLYAATAATVPKVPEAPEGLVVLAQESVDDGAGVLIFYGDADPAAAKKRDESGLSKRCGSNQVSCFGSHRAPIWLCSALLYQLEISSTQLQESPRSICKQASSKQCCVSWAHPVSGGKKDNLAPAGYKVNSECNWGDNTVSGLTRDTQIGNTCTTQCLSNRPDGCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0B731</accession>
    <name>X0B731_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979371">
        <property type="protein sequence ID" value="EXK77945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B731"/>
    <dbReference type="HOGENOM" id="CLU_040562_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06503">
        <property type="entry name" value="ATP-synt_Fo_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="49"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="240" mass="27558" checksum="FC7069C3CBE1D804" modified="2014-05-14" version="1">MGNDASLMQIMLQAMLQETSSHIMSEQKKMLERLWDALMANQRTATQMISEQLEMIRQLQQEIQAVKAQAAEELKKADEFRCMHEQATRQLRIMREQTSEQIRAMREQTNEQLKSLSEQAARELEQMREQVMNELRKAQAQTAEETKQVNEQLNMMANSISNRTQPSPQPTYVDIARTPPTSHPSNTRTLSPTRTTPSSFTDTLFCTIDTSRVSKEDRGKAQVGEVRQAIEEEVRARGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B735</accession>
    <name>X0B735_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979371">
        <property type="protein sequence ID" value="EXK77950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B735"/>
    <dbReference type="HOGENOM" id="CLU_1214801_0_0_1"/>
    <dbReference type="OrthoDB" id="5033801at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="25108" checksum="80A6386D0BFEFE39" modified="2014-05-14" version="1">MGKFIDIKFLPAPKNDAGGQAAGQKLKSMAGDARDEKPGYEGVFSGRPLEQQEVVEILDVWDKESSWRAKEMSPDQEQVRKLLDGLCEGAGLDISSLKAFKNQFLLDSDFTPALDEGIMRMEIFLLPISSNETGFQQTVMTVLGSVTSVTTGWSLKEAEYDSRGWRALLMLTKWESLAQSETALSESSRSLNAILEQKEARTLVHHIKWKNPLTQVGLAVSGGVNQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0B8P3</accession>
    <name>X0B8P3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_17172</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658543">
        <property type="protein sequence ID" value="EXK78141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B8P3"/>
    <dbReference type="HOGENOM" id="CLU_028200_3_6_1"/>
    <dbReference type="OrthoDB" id="3936451at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="49"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK78141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="240" mass="26539" checksum="CDC4ED5E05605166" modified="2014-05-14" version="1">MPLPTSGKGLELLIIQICCSVIVYISACLRLWAQHVNRNRQLQHNNTAKKKQSPHDILMLASVLLYTVQTIIVIRGIIEGGIGQHASKIDIAEVTKGFQTWYFGELIYAMLSCLVKTSVILFLQEAYIGRRKIRKATDRRKICWILYICLAVIWATSIVFLSASIFQCSPPSHYWKQFENPSSEGACSKSVVPAAGIALSIVSAVSDWVLASVPTVALLKTQIPWQKKAAIQALSSLGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAG5</accession>
    <name>X0BAG5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_16598</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979353">
        <property type="protein sequence ID" value="EXK78746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979353">
        <property type="protein sequence ID" value="EXK78747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAG5"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_3_1"/>
    <dbReference type="OrthoDB" id="5215911at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF30">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04702)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="50"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK78746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="540" mass="59887" checksum="E53DB5A28568935C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBP0</accession>
    <name>X0BBP0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_19309</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979703">
        <property type="protein sequence ID" value="EXK75929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBP0"/>
    <dbReference type="HOGENOM" id="CLU_028200_25_2_1"/>
    <dbReference type="OrthoDB" id="5342292at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="8"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK75929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="190" mass="21463" checksum="98B10CD6EF7BC6E8" modified="2014-05-14" version="1" fragment="single">MFEPALTMSAETRNGVGVHIWDVPLSSFNRFMMLGAIPGAITYNLSTLFTKVSILHFYLRFSQDRAFKLATYFVMFVVVGNNLPAAFAFLYMCRPITRYWDYTRPGSCLDVGSAFIVCAVLNSVTDIIILCLPIWLLRPLRMRRLQKIGVTLVLMAGGFVCAVSLIRLASIPSGLHNPDVTWRYVINLIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BBR4</accession>
    <name>X0BBR4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979557">
        <property type="protein sequence ID" value="EXK76253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BBR4"/>
    <dbReference type="HOGENOM" id="CLU_086094_0_0_1"/>
    <dbReference type="OrthoDB" id="5020742at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="23935" checksum="1CEA4D3305291DF1" modified="2014-05-14" version="1">MKRNILVEYTLRSIALVLEIAALSSIFLGIQGASGYFAWFIGQRLSPSLLDTFLPGSQEALLCFVLNTIFFLVVLWGILPFYSIRKELPFFVSGLVVCSVGQLAVALTIMSIHVAFTAWDWSILLEEDGYMSLAKHCRAMSIFLSTLWCMGWIFFILSLSYVLNFGVPDFLQQMLVDTRKLLAAARIKPLPHPAWVDKEDFITSEEAANLVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCF6</accession>
    <name>X0BCF6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_15940</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658470">
        <property type="protein sequence ID" value="EXK79471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCF6"/>
    <dbReference type="HOGENOM" id="CLU_004495_5_1_1"/>
    <dbReference type="OrthoDB" id="2417308at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF11">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK79471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="297" mass="32440" checksum="5DB6B148D90220A7" modified="2014-05-14" version="1">MSILASGYAELASAFPSAGGQYHIVYMTFPASTRRFAAFFTGRMSILYTMGATASCSFFVAQSILNLVALWNETYVIQSWHVYLVHICSCTIAFLAASRFPAAIGSIGVSVFWMSIIGFIASLATLLAVQEVKQPSKFVCTEFTNVSGWTDGWAAMIVDNPSRNIPIAIGATIILGVITAIDWNIGLMYVIKDVQGLIASGAPIMEVYNQALGSKTATTIWSVYYILVFYNVTLNLLVFSSRILWSFARDGGVPYSSYVSRLRWSNPVRATAIMLFLQIIIGILYIASKQLIVASST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDK8</accession>
    <name>X0BDK8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_15278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658449">
        <property type="protein sequence ID" value="EXK80200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDK8"/>
    <dbReference type="HOGENOM" id="CLU_2794010_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="73" mass="7877" checksum="4B47CF0F4C072D77" modified="2014-05-14" version="1">MVTRIGGAVSEDLFQKVEDSLTQKLLSPEAYGLMANLPLHYGAALYGLGTLAELEAGNLLLFFPDPVLQRSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEH0</accession>
    <name>X0BEH0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_15266</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658449">
        <property type="protein sequence ID" value="EXK80186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEH0"/>
    <dbReference type="eggNOG" id="ENOG502SKNC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016203_0_0_1"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF6">
        <property type="entry name" value="PROLINE UTILIZATION TRANS-ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="11"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK80186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="480" mass="54852" checksum="57A3DCC1F6A3A704" modified="2014-05-14" version="1">MQRRSAGTQRQRVLQACDFCHSRGLKCRRSSMTETTSRDGHRTCLTCIDYGAECTMNRPVRKRGRKPAVTTGKSNKQKQTGSESSDFRSPQCIRRLIDIYRDTMYQCYFPFLSENDLERRWADSIPGDSETAYLLLMALCALSAQSLTLKAVFDSTLLGNVVSHDSDIYFNEAVSHIPARIPDTPDLDYLRSFGLLAVYLLRSGSKSDLHRYLGLCHAWIAQHGFNMENNWDSSISLLEVDDRRRLFWCVYRLEIHSACVLGHIIRLPEAQVSVLYPRITPAMSRETQAWTAGWDYITDLFRLMEYAILNLRQRKPHRDVVAVFCDRPSPRALLDSLDQLKASKPFILRVLSQSHDDFQSNRCKFMAVQITCTEALVNIMGLLHCQAPVDEVIKVAEDFLNEITEASLIMFKVASSQIVHQLLGVGHMVYNAFLYDENQSQFAVGRLVTYLEDIVKNLEQDIPTATEAREQLRKLAKCII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFC7</accession>
    <name>X0BFC7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glucan 1,3-beta-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_18125</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the secreted LysM effector family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979413">
        <property type="protein sequence ID" value="EXK77159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002540_4_1_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF16">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="924"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="1071"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="1134"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="1237"/>
            <end position="1331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK77159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1338" mass="145100" checksum="CED376F0AA345C94" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGH0</accession>
    <name>X0BGH0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxyanthranilate 3,4-dioxygenase</fullName>
            <ecNumber evidence="9">1.13.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">3-hydroxyanthranilate oxygenase</fullName>
            <shortName evidence="9">3-HAO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">3-hydroxyanthranilic acid dioxygenase</fullName>
            <shortName evidence="9">HAD</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Biosynthesis of nicotinic acid protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BNA1</name>
        <name evidence="10" type="ORF">FOQG_14600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:17953"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:77612"/>
            <dbReference type="EC" id="1.13.11.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 3-HAO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.6" evidence="9"/>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGH0"/>
    <dbReference type="HOGENOM" id="CLU_095765_0_0_1"/>
    <dbReference type="OrthoDB" id="204928at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000334">
        <property type="term" value="F:3-hydroxyanthranilate 3,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:L-tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06123">
        <property type="entry name" value="cupin_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00825">
        <property type="entry name" value="3_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010329">
        <property type="entry name" value="3hydroanth_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03037">
        <property type="entry name" value="anthran_nbaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497:SF3">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06052">
        <property type="entry name" value="3-HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 9" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK80911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="176" mass="20545" checksum="2CC54E4D61565035" modified="2014-05-14" version="1">MARDPLNFPRWLAANSDRLQPPVSNFCLYDGKDFILQVVGGPNTRNDFHVNSTEEWFYQIKGSMLLRLIEDNQIRHVTIREGEMFLVDANTPHSPARTADTVGLVMEMVRPSDNLDCLRWYCTKGNHSEPTLIHEESFYVSNLGKQLIDPIERWRRDEKRRTCPKCGKVEDPQYYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGT6</accession>
    <name>X0BGT6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14466</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979336">
        <property type="protein sequence ID" value="EXK81036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGT6"/>
    <dbReference type="eggNOG" id="KOG1336">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_1_2_1"/>
    <dbReference type="OrthoDB" id="361797at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050260">
        <property type="entry name" value="FAD-bd_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43429:SF1">
        <property type="entry name" value="NAD(P)H SULFUR OXIDOREDUCTASE (COA-DEPENDENT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43429">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="7">
        <location>
            <begin position="461"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK81036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="549" mass="59884" checksum="06EB2A640CC63345" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGZ0</accession>
    <name>X0BGZ0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_17605</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658582">
        <property type="protein sequence ID" value="EXK77704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGZ0"/>
    <dbReference type="HOGENOM" id="CLU_1975757_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK77704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15744" checksum="AA621AE450CC09CC" modified="2014-05-14" version="1">MRELHDRYGDVVRIAPNELSFKTPQAYKDIYNHAVGHKTPFPKSKYFYNRGASIKHPDIVFTIDRESHRSQRRSLSHAFSARALREAESTIQRHARLFVHQISQRGNPGTGGVDMSAAFTWLTFDIIGVLHQLARNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI44</accession>
    <name>X0BI44_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Xylan 1,4-beta-xylosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_13799</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658421">
        <property type="protein sequence ID" value="EXK81820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI44"/>
    <dbReference type="eggNOG" id="ENOG502QZZ0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016508_2_0_1"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18617">
        <property type="entry name" value="GH43_XynB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF16">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06110)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936331" evidence="7">
        <location>
            <begin position="22"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="8">
        <location>
            <begin position="344"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="5">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK81820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="559" mass="63319" checksum="2AE90437E2E8020D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKF9</accession>
    <name>X0BKF9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Flavin prenyltransferase PAD1, mitochondrial</fullName>
            <ecNumber evidence="6">2.5.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PAD1</name>
        <name evidence="8" type="ORF">FOQG_16024</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for the ferulic acid decarboxylase FDC1. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dimethylallyl phosphate + FMNH2 = prenylated FMNH2 + phosphate</text>
            <dbReference type="Rhea" id="RHEA:37743"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:87467"/>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
            <dbReference type="EC" id="2.5.1.129"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Oligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the UbiX/PAD1 family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.129" evidence="6"/>
    <dbReference type="EMBL" id="JH658473">
        <property type="protein sequence ID" value="EXK79373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKF9"/>
    <dbReference type="HOGENOM" id="CLU_074522_3_1_1"/>
    <dbReference type="OrthoDB" id="5126881at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106141">
        <property type="term" value="F:flavin prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1950:FF:000001">
        <property type="entry name" value="Flavin prenyltransferase UbiX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01984">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004507">
        <property type="entry name" value="UbiX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004685">
        <property type="entry name" value="PRK06029.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00421">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1 6" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavoprotein" evidence="7">
        <location>
            <begin position="43"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="51"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK79373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="245" mass="26951" checksum="BFA1CB53480D48A0" modified="2014-05-14" version="1">MRSFARPLRLFSGHDLPKPSMARHLPAQTRYQPSSPGPNGRPKRIVVAVTGATGSPLAVALLQRLRELDVETHLVMSKWGGATLKYELEVPNNTTSYLESLASVTHSSLDVSASLSSGSFRTDGMIVVPCSMKTLAGIRMGYDNDLIVRAASVTLKERRRLVLVARETPLTSIYLENMLEVTKAGAVVFPPVMAFYTRPSSIDDMVQQSVMRMIDLLDLEVIDGNMQDEARWSGFDWAAKGKQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BL76</accession>
    <name>X0BL76_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase tdiE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658477">
        <property type="protein sequence ID" value="EXK79194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BL76"/>
    <dbReference type="HOGENOM" id="CLU_010595_2_3_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK79194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="31609" checksum="9283578E9E55FCF6" modified="2014-05-14" version="1">MPNDETENNRLDLQHNLFLLTFDNKLGLSPPNLPELKTGRVLDLDLDSVPPNIKFEIDDIDEDWTYSQPFDYIHSRMMNVSVKNWSEYIRKVFENLTPGGYAEFQDVDVLMQSDDNTLTEDHALRKWGVLLAQAAQEHGTRFIETDRLSHLMAEVGFVEVKETPFKWPTNRWLKERKYKELGEWSNLNTSDLLDGLSMALFTRCLGWTPEEVRVFLIDVRRDLNNPKVHAYWSMYYSPNRSLSQCTDTLLVVQFTGGSLTFRDWMGRYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMH6</accession>
    <name>X0BMH6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12402</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658403">
        <property type="protein sequence ID" value="EXK83385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMH6"/>
    <dbReference type="HOGENOM" id="CLU_397958_0_0_1"/>
    <dbReference type="OrthoDB" id="1405595at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF18">
        <property type="entry name" value="NICOTINATE CATABOLISM CLUSTER-SPECIFIC TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="96"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK83385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="591" mass="66983" checksum="57E7BB0043C06731" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0BN56</accession>
    <name>X0BN56_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_12442</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658404">
        <property type="protein sequence ID" value="EXK83261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BN56"/>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000023">
        <property type="term" value="P:maltose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000149">
        <property type="entry name" value="MFS transporter, SP family, general alpha glucoside:H+ symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF5">
        <property type="entry name" value="ALPHA-GLUCOSIDES PERMEASE MPH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="427"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="501"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="79"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK83261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="573" mass="63961" checksum="AB361AFBBF8F8B79" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNM9</accession>
    <name>X0BNM9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sialidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNM9"/>
    <dbReference type="eggNOG" id="ENOG502QTE2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007128_0_0_1"/>
    <dbReference type="OrthoDB" id="504663at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43752">
        <property type="entry name" value="BNR/ASP-BOX REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43752:SF2">
        <property type="entry name" value="BNR_ASP-BOX REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="Sialidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialidase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="380" mass="42219" checksum="0F4EAEF8D4AA1044" modified="2014-05-14" version="1">MAPNLQTIPVPSATVQSHASNLLQLPDKTVLCTWFGGSQEGLPDISIWLSRLEPGSSSWTTPQKVSFDENRSCQNPVLFRAPHSGEIWLLHTSQDAGNQDGAYILKRTSSDQGHTWSEASRLLPDVTGIFIRQPIVINGDGTWILPVFYCRTEPGHRWIGSDDISGVLYSDDNGATWKEKQAPDSVGSVHMNIIPPVSGSSSWVAFYRSRWADNVYRSTSNNGIDWETPKATTLPNPNSGICAARLSSGRIAIVFNRSNASADTLKRQGLYDDITPEDDKRPNQVTKTGKDAIWGTPRKTLTLGVSEDEGLTWRERVLEDGDGFCGTNSSSGQENRELSYPSIYIEKDGDRDVAHVAYTWHRQHIKYVRIDDVEGWVRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP13</accession>
    <name>X0BP13_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_15255</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JH658449">
        <property type="protein sequence ID" value="EXK80174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP13"/>
    <dbReference type="eggNOG" id="ENOG502SHYE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_1_0_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152146" description="Carboxylic ester hydrolase" evidence="10">
        <location>
            <begin position="24"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK80174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="532" mass="59259" checksum="25244C90AB00236C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPH1</accession>
    <name>X0BPH1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_15081</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658446">
        <property type="protein sequence ID" value="EXK80374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPH1"/>
    <dbReference type="eggNOG" id="ENOG502S6CG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029871_3_2_1"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF1">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938775" description="Heme haloperoxidase family profile domain-containing protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="83"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK80374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="452" mass="49321" checksum="33DB7E2C8DFF217C" modified="2014-05-14" version="1">MKPFTLATLATALLSNQATALPKLNADTPIPLNAFKFGARDAKNPHLGVDPELIRKFASQAPPNLGKRVIDFDPKEQLVDVHGKHEFNPPDFEAGDVRGLCPGLNTLANHGYLPHNGVATFTQYVTAVGKVWGMAPDMSALLTTLGVVLGGNLVAVSQGGWSKYMNNNLLGLFGTPRGLSGSHPFFEVDGSPTRGDLYDPIGDNNDMNMTYFMELYNLQKDAENPNYSIEVLYEHNKNRWHQTIATNPYAWFGPASGWLVRASPYSFTARLAANRSAENPDDGILDKEMLKAFFSVYGPEENMTYVVGHERIPENFYRRRYTDYGIAANALDIVTHSHPEVLSIGGNTNGVNTFVGINFNDLAGGVLNGKNLLQGNNLVCFALNAIKTVSPNALSSLFATLSSVTDVLFAALEPIMGAMDCPVYKDLSVNGTNWLDYNKKMYPGFKKAGGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ44</accession>
    <name>X0BQ44_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979336">
        <property type="protein sequence ID" value="EXK81038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ44"/>
    <dbReference type="HOGENOM" id="CLU_033726_0_0_1"/>
    <dbReference type="OrthoDB" id="2245989at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF1">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="35339" checksum="82E56CE69284D5DF" modified="2014-05-14" version="1">MTESSPQQNNTAMKYPINVDAVPLIKLSDMEQRREIRTASEDWTGITSSAERRKLQNRLNQRAYERRKASRRSASLHLKQGSRPRYVSMATTDTPDAPEPPSALQYLNLIKPPAGFKPRSGCLLLRPDAQGAIREFVKKAYEDYVLGCPQPWYLSTLIQVNVFNALVQNGVALGFSDRWQRKGVVSPFSIIGPVQSCDSYPLNLQPTALQRAVPHHPWIDLFPIPQMRDNILLSLRHLDMDELCGDLLDVKPGLDGKPSLIVWGDPWDLRGWEASPLFLQKWGWMLEGCRDILQATNYWRESRGEDKILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQP2</accession>
    <name>X0BQP2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent RNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_14357</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658428">
        <property type="protein sequence ID" value="EXK81213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQP2"/>
    <dbReference type="eggNOG" id="KOG0947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002902_1_4_1"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000354">
        <property type="entry name" value="ATP-dependent RNA helicase SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000987">
        <property type="entry name" value="DEAD/DEAH box RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000001">
        <property type="entry name" value="Ski2 ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040801">
        <property type="entry name" value="Ski2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17911">
        <property type="entry name" value="Ski2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="310"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="597"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="194"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="509"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="534"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="555"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK81213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1275" mass="142512" checksum="A00DFC5F5C009D2E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRF3</accession>
    <name>X0BRF3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658426">
        <property type="protein sequence ID" value="EXK81503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRF3"/>
    <dbReference type="eggNOG" id="ENOG502QSAC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032323_1_0_1"/>
    <dbReference type="OrthoDB" id="2283785at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039634">
        <property type="entry name" value="Bul1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904:SF1">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="447" mass="50034" checksum="480A638B03B9A24F" modified="2014-05-14" version="1">MEPPYTQRSGVPLQTRPVLSPFNPSALQSINSILPPKKNGMTINIHDHYASKRYRPGSIVMGTVNIKPKKQIPFTKVSIKFVCDSSVERPNANLSFETWHRLLDLEMPIEEAALPTTKILQANETYTVPFYFVLPNGLGTEACSHNVIWQETRQLHSHLPPSITGWESDAMIPRGVRVDYGVIAQVWDSTSPEYAKMEAKETVQFLPGHVEHPPLKIPTANRTFKFGSSKQLKSNVFCRSSGEITLYTDQPNAIVLDSSGKSFHPTTITTSLRLKLCDQKTSLPQTCSVSAKIESETWSQDEPMQQLPHIVNARDCYNGSDTLVKKSEVGLRWEKNSPKQTDSIVTETAETFSSHIEIPITSFASDKKMFLPTFYSCLIARTYQLHLTINVASTTLKLVLPVQLTMEEQKGDVQPDAEDIGLPESSARCSSSLPSYIESERRHSQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRV8</accession>
    <name>X0BRV8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_14340</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH658428">
        <property type="protein sequence ID" value="EXK81184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRV8"/>
    <dbReference type="eggNOG" id="KOG1290">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2649at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14136">
        <property type="entry name" value="STKc_SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000409">
        <property type="entry name" value="CMGC/SRPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000076">
        <property type="entry name" value="CMGC/SRPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="101"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="258"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="276"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK81184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="567" mass="62759" checksum="C43EC13806007FAC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSA4</accession>
    <name>X0BSA4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658421">
        <property type="protein sequence ID" value="EXK81797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658421">
        <property type="protein sequence ID" value="EXK81798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSA4"/>
    <dbReference type="eggNOG" id="ENOG502QPW3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002616_2_0_1"/>
    <dbReference type="OrthoDB" id="3665757at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10318">
        <property type="entry name" value="RGL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041624">
        <property type="entry name" value="RGI_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034641">
        <property type="entry name" value="RGL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049366">
        <property type="entry name" value="RGL11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43118">
        <property type="entry name" value="RHAMNOGALACTURONAN LYASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43118:SF1">
        <property type="entry name" value="RHAMNOGALACTURONAN LYASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18370">
        <property type="entry name" value="RGI_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21348">
        <property type="entry name" value="RGL11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738217" evidence="1">
        <location>
            <begin position="21"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan I lyase beta-sheet" evidence="2">
        <location>
            <begin position="23"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase family 11 C-terminal" evidence="3">
        <location>
            <begin position="138"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="599" mass="67014" checksum="B3F551C44C3DDD45" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSJ2</accession>
    <name>X0BSJ2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Enoyl-CoA hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_11076</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSJ2"/>
    <dbReference type="eggNOG" id="KOG1680">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000074">
        <property type="entry name" value="Enoyl-CoA hydratase (AFU_orthologue AFUA_2G10650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF158">
        <property type="entry name" value="ENOYL-COA HYDRATASE (AFU_ORTHOLOGUE AFUA_2G10650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK84836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="290" mass="31558" checksum="D87CCF02F8B4C515" modified="2014-05-14" version="1">MAQHTFNRQPPAQSYGLVSFPAQHVMLVVFNRPKALNAMTSDAEYELEALWEWYDDEPSLRCAIVTGAGRAFCAGMDLKEWNQINQRKRDGIPEKRPMDPPTTGFGGLSRRSGKKPIIAAVNGLAMGGGFEIIANLDLIVAAKSATFALPEAKIGVVANAGSLPRLARTIGRPRATEMALTGRSISAAEACEFGFLNAITEDAPPDSDVLERPVVQKALEYAALIIKNSPDSVIVSRAGILAGWEHGSAENAVRVHRQTWDKIMADGHNFHEGVQAFVEKRAPRWVDSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSZ3</accession>
    <name>X0BSZ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">AAT family amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_14025</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658425">
        <property type="protein sequence ID" value="EXK81614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BSZ3"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF4">
        <property type="entry name" value="ARGININE PERMEASE CAN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="46"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="517" mass="56494" checksum="2B479FC0E44C89C9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTU1</accession>
    <name>X0BTU1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_13673</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658419">
        <property type="protein sequence ID" value="EXK81914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTU1"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="15"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK81914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="504" mass="54815" checksum="63432EC305B1F80F" modified="2014-05-14" version="1">MASTTRGPIFSHILILLVAMLNLCILSYDAGMINNLNKVKPYYDYFNLNSDIVGLNGAIISAGCIVGGPLVGPIVDRWGRKAGLLMGSLCILLGVALQASAGGVPQLIVGRFIIGVATLVNGSIAPMWVMELASPKYRSALSNSVVTSVPFTSFLVSCMTLGIHNAKSDWAWRGIMFVKAIPSIISLCLLPFVDESPRWLLAKCRKNEATEILARLHSNGNHEHPMIVAEIQEILGALEQEKKTKGGWKELIWPVPNLKRFSICVLVNIFYQILGGNMILYFSSSIIGNLRIENPATVIKINMGLLLFKTLCSVGGVFIIDWIGVRKPLIAGTSAIVALFGLLAGLSYLADIHPDIPGYAISALIVVALFLLAVSTSWMLLAYTYPIEVLKYSQRAKGVVVAQAIGYAFSFLNLYTAPVAIEKIAWRYYAINGGWDLGILLIVVLMFVETKGRTLEEMDELFEGVGYNDGMTIGQNTVARLEQEESVGTGSINKSRSMTSIDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUY7</accession>
    <name>X0BUY7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_12997</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUY7"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF29">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="56"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK82723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="527" mass="58550" checksum="CF14BC81B2FFE438" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVZ8</accession>
    <name>X0BVZ8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVZ8"/>
    <dbReference type="HOGENOM" id="CLU_2812447_0_0_1"/>
    <dbReference type="OrthoDB" id="10378222at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="61" mass="6902" checksum="FF3CA92F90D897C1" modified="2014-05-14" version="1">MPAYRFNITISLFGMAFVLTLQVYRDDLPLPHRHPYRRGGGRRGRGGRGRGGGRSYPRIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW89</accession>
    <name>X0BW89_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW89"/>
    <dbReference type="OrthoDB" id="5342924at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="689" mass="77010" checksum="A827765BBA57728D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXF2</accession>
    <name>X0BXF2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">U6 snRNA-associated Sm-like protein LSm6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_09615</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXF2"/>
    <dbReference type="eggNOG" id="KOG1783">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076902_7_4_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01726">
        <property type="entry name" value="LSm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000037">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF1">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 15" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 15" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 15" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="10 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="9 15" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Sm" evidence="16">
        <location>
            <begin position="13"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR006609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK86865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="83" mass="8995" checksum="ECAA23A4E6B94BF9" modified="2014-05-14" version="1">MENGAISQGEGKDPSSFLSDIIGNPVTVKLNSGVVYKGELQSVDGYMNIALEKTAEYVNGQKRREYGDAFVRGNNVMYISADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYX9</accession>
    <name>X0BYX9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYX9"/>
    <dbReference type="HOGENOM" id="CLU_3377095_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="34" mass="3266" checksum="1877D6D061BD6F5A" modified="2014-05-14" version="1">MAAASCRSASGLVWSATVDSHSPLASDAACAVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0C035</accession>
    <name>X0C035_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C035"/>
    <dbReference type="HOGENOM" id="CLU_2941757_0_0_1"/>
    <dbReference type="OrthoDB" id="5104613at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="60" mass="6685" checksum="5D1B020D02608C48" modified="2014-05-14" version="1">MTPSPAVAIAILFLTLFAIFALLAWWLKTRVHTFIRAIFKHRQEKNKGNASTVANSGESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0K2</accession>
    <name>X0C0K2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PD-(D/E)XK nuclease-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18924</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979535">
        <property type="protein sequence ID" value="EXK76332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0K2"/>
    <dbReference type="HOGENOM" id="CLU_027219_0_1_1"/>
    <dbReference type="OrthoDB" id="4161186at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046797">
        <property type="entry name" value="PDDEXK_12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20516">
        <property type="entry name" value="PDDEXK_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PD-(D/E)XK nuclease-like" evidence="2">
        <location>
            <begin position="209"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="465" mass="52191" checksum="21566C7EDE987C05" modified="2014-05-14" version="1">MSHSTSILAWLDSICNDRKLGSEPLTEPSLKHTIKQEDRKRRLPSPPSEDETRIFRVSQMDNTGPPKKPKVGPITDASDPRLRLSAPKRTRDPHDNGSDQEDGGHIPRTSESGVETGSRSARSRKKASPSRVSMSASSSPSRRLHGLSLENDGLVTRDLDIGDKRQPPLLKALLTKIDGWSTRWGILHSSMRGVFGDDVSQYGFHEDVAFSAEPNDCGSRLSLKDAEEILDRARECRDLSHSEMAWNFEVHQYLLEKIFRADDRPYLVNFSSSHSASIIKEYLPTTTGSKLVDFCIYVNPGADRNKEKDYGTQTNDLSRILPMQCLNHTSYLGLAARPISASIETKRTGDDEDNAALQIGTWQAAQWNYLESLLIRIGGEEHAETALTDLGLLPAIITHGHQWSFAATTREGGKIVLWRQFIFGRTSSIAGIYAIATVVEYLRHWTETAYWEWFKRNILDRSEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0Y6</accession>
    <name>X0C0Y6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11078</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0Y6"/>
    <dbReference type="eggNOG" id="ENOG502S0DZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035734_1_1_1"/>
    <dbReference type="OrthoDB" id="2140105at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022703">
        <property type="entry name" value="DUF3533"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053001">
        <property type="entry name" value="MNNG_permease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814:SF2">
        <property type="entry name" value="DUF3533 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12051">
        <property type="entry name" value="DUF3533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3533" evidence="3">
        <location>
            <begin position="34"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="481" mass="54102" checksum="5897A60454F71DC9" modified="2014-05-14" version="1">MTLIPPRSSNRISSRSTPLSVRMKTYIIPVIMTALMVQLLFLANMSYLFGSLFKSSTRMHNLKILAIDFDGSDIGKAISGAYDTLQSDKFPSVEFGSSSEYDTPEKVRDAVCNHGYWGAIYTHPGASDRLLSTIEGDNTTVYDPQDAVTTIYNGAYYPSIFSSLQGNMQSLVGAAATMYALATPDALKAVNMTNPTSASTLLRPFHANIWNIMPTEQGTRVLLNTVSLVMGILMHFFFQMGLNGITTSTKVLQSYSKRDVYIFRFITGKIYTLIGALGMAGYFWAFRENWSVDAAQFFETWMCLWFYMDINYLVIDTVLATIVPMQFFAFFLLTWIILNIGSTVFPFELTPGFYHWSWALPAHNAWLLLVGIWSGCRANIGVTLPILFSWWVVGHAGSAWSVRKRCLMAEAEAENQLQDTPNEKFERFSTEQTRQETSHGLRPAQDLDLEANLPAQRLRNDDDNRTITNGGEPSQERDNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1D7</accession>
    <name>X0C1D7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c oxidase assembly protein subunit 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_08573</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX17 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1D7"/>
    <dbReference type="eggNOG" id="KOG3496">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149618_3_0_1"/>
    <dbReference type="OrthoDB" id="1915887at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1130:FF:000004">
        <property type="entry name" value="Cytochrome c oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007745">
        <property type="entry name" value="Cyt_c_oxidase_Cu-chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05051">
        <property type="entry name" value="COX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 8" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR607745-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK88195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="76" mass="7969" checksum="71CCCA408F3C1437" modified="2014-05-14" version="1">MDAAQTTISSPVGAAANVASPSTTAASKPKPCCVCKDEKAKRDECMLFSNAKDPAADCKSLIDQYRSCMSGFGYQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2B8</accession>
    <name>X0C2B8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_18333</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658663">
        <property type="protein sequence ID" value="EXK76937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2B8"/>
    <dbReference type="HOGENOM" id="CLU_028200_3_0_1"/>
    <dbReference type="OrthoDB" id="5417887at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="42"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK76937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="359" mass="39574" checksum="89AB4141DCA265C1" modified="2014-05-14" version="1">MLTDHTQGSGAQAEDLPHDSRGPTLLAIFWSAVASSAMILGLRLYCKIRTGRGLWWDDYIALSSWVSLVIFISLETYLVVPLKYGSPDWDIPPENLALTATIAAAAYPFLLLSIMWSKTSFGVTLLRITTEWMKRAVWGLIISTNVFLGFSILIYYIQCTPVQALWDIRVKGKCWDRDIAMKYHVFSGVWSSAVDLTLVFFPWKILWGAQMLGREKWGIAIAMSMGIFAAVASSIKTAQLHLLSSTSTYKAVPVMYWGPIEIATTIIAASIPALRLLIKDVRTSARQHQRANEGRDSISRARCNLELHYVARLSSGRGSEDNIIPIAAGRGMEMTADASGVWKDSGAEKGTGPHGTNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C519</accession>
    <name>X0C519_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C519"/>
    <dbReference type="eggNOG" id="KOG2495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029131_0_0_1"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF24">
        <property type="entry name" value="NUCLEOTIDE-DISULPHIDE OXIDOREDUCTASE AMID-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="85"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="494" mass="53960" checksum="EFC77CE7F7F84EEB" modified="2014-05-14" version="1">MLIARVSARFSGQLLRVPHATLSQAIRFFTSSSLHTTLALPRPQIQVRSVVLASHLVFRRQNRSTSHSKAFATMGSLPESSNAVRVLILGGCYGGLSAAVNLLDLSQGYSPRMNSEPYIHHPDLPRFNVDITIVDERDGYYHLIGSPLALADSNFSKKNWVKYSDIPGLKDPSINIIQGSVTSVDPATKKATISAHLTKEKSTLEYDYLVSATGLRRVWPVVPQSKTRKQYLLEAENHITSVHNAKHGVMVVGGGAVGIEMAAELKMVKPHLKVTLIHSRDKLLSSEGLPDETKDVALQLLREAGVEVLMSHRLAANNKVETTDGSEKYEIEFTNGHKMFASEVIMAISRSVPTSTYLPTSALDADGLVKIKPNLQLQDGTPNAESHYAAGDITNWPGIKRCGGAMHHGHYVAQNIHQSILSQRAGHTPEFKELVVYPPVIGLAVGKKAVASSPDTGTVYGEEVAQSCFRDDLGWTICWNYMQLGGRKTDEAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6B0</accession>
    <name>X0C6B0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_17045</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658531">
        <property type="protein sequence ID" value="EXK78267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6B0"/>
    <dbReference type="HOGENOM" id="CLU_000288_34_2_1"/>
    <dbReference type="OrthoDB" id="1577640at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="4">
        <location>
            <begin position="82"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="6">
        <location>
            <begin position="437"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="5">
        <location>
            <begin position="721"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="935"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK78267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="974" mass="109190" checksum="AAAFF1F11BF35DB5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6P9</accession>
    <name>X0C6P9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="13">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_09751</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 20">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="13"/>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6P9"/>
    <dbReference type="eggNOG" id="KOG1123">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008213_0_0_1"/>
    <dbReference type="OrthoDB" id="10262986at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18029">
        <property type="entry name" value="DEXHc_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000077">
        <property type="entry name" value="Probable DNA repair helicase RAD25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000117">
        <property type="entry name" value="Putative DNA repair helicase rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00851">
        <property type="entry name" value="XRODRMPGMNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="281"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="497"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="729"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="740"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK86484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="758" mass="85444" checksum="5A7A062CC1983C86" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0C872</accession>
    <name>X0C872_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C872"/>
    <dbReference type="eggNOG" id="ENOG502SH42">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4455544at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1024"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1030" mass="115369" checksum="BB9FD05E62F73F24" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0C947</accession>
    <name>X0C947_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C947"/>
    <dbReference type="HOGENOM" id="CLU_2671136_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="75" mass="8655" checksum="B6FF15886E3556B8" modified="2014-05-14" version="1">MDSNVSRLNLESRLLVNMCSKISPESKSEQKIARILLLRFMNDGKDLSDKLVLLHNYSSRTHSKVKSYQEMNAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB09</accession>
    <name>X0CB09_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SWI/SNF and RSC complexes subunit ssr2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_06326</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB09"/>
    <dbReference type="eggNOG" id="KOG1279">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004447_3_0_1"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016514">
        <property type="term" value="C:SWI/SNF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02336">
        <property type="entry name" value="ZZ_RSC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000020">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000014">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041984">
        <property type="entry name" value="Rsc8/Ssr1/Ssr2_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032451">
        <property type="entry name" value="SMARCC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF41">
        <property type="entry name" value="BRAHMA ASSOCIATED PROTEIN 155 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16495">
        <property type="entry name" value="SWIRM-assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SWIRM" evidence="7">
        <location>
            <begin position="111"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="8">
        <location>
            <begin position="372"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="373"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="488"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="648"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="506"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK91600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="672" mass="73365" checksum="369BB1901ECFC20B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBA7</accession>
    <name>X0CBA7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Succinate/fumarate mitochondrial transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_08327</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBA7"/>
    <dbReference type="OrthoDB" id="204711at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005469">
        <property type="term" value="F:succinate:fumarate antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000021">
        <property type="entry name" value="SFC1p Mitochondrial succinate-fumarate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF2">
        <property type="entry name" value="SUCCINATE_FUMARATE MITOCHONDRIAL TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="13"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="115"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="219"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK88513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="35694" checksum="54FB21C50920A194" modified="2014-05-14" version="1">MASKNGNGKKQPPSAAVNLIAGGGAGMMEALACHPLDTIKVRMQLSRRARQPGAPKRGFIKTGAAIIAKETPLGLYKGLGAVLTGIVPKMAIRFTSFEWYKQILADPTTGTVSGKATFIAGLSAGVTEAVAVVTPMEVIKIRLQAQHHSMADPLDVPKYRNAAHALYTVVKEEGFGALYRGVSLTALRQGSNQAVNFTAYSYFKDWLKKWQPQYENTNLPNWQTTLIGLVSGAMGPMSNAPIDTIKTRLQKATAEPGVSAWTRITRIAGDMFKQEGVHAFYKGITPRIMRVAPGQAVTFTVYEFLKDKLEKSNISLVGVQVAVKEAEESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CE06</accession>
    <name>X0CE06_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar protein-sorting-associated protein 36</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ESCRT-II complex subunit VPS36</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_05716</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the VPS36 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CE06"/>
    <dbReference type="eggNOG" id="KOG2760">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015433_2_0_1"/>
    <dbReference type="OrthoDB" id="271448at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000165">
        <property type="entry name" value="Vacuolar protein sorting protein (Vps36)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000527">
        <property type="entry name" value="Vacuolar protein sorting protein (Vps36), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021648">
        <property type="entry name" value="GLUE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037855">
        <property type="entry name" value="Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031558">
        <property type="entry name" value="Vps36-NZF-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128:SF12">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16988">
        <property type="entry name" value="Vps36-NZF-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11605">
        <property type="entry name" value="Vps36_ESCRT-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51495">
        <property type="entry name" value="GLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0967">Endosome</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GLUE N-terminal" evidence="11">
        <location>
            <begin position="6"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="94"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="198"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="269"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="334"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK92645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="645" mass="70048" checksum="005902AD101CE419" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEZ3</accession>
    <name>X0CEZ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_14412</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658429">
        <property type="protein sequence ID" value="EXK81167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEZ3"/>
    <dbReference type="HOGENOM" id="CLU_004804_2_1_1"/>
    <dbReference type="OrthoDB" id="6509908at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47840:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47840">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="15"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="703" mass="78884" checksum="11B3A7D70A099973" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFC3</accession>
    <name>X0CFC3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_05308</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFC3"/>
    <dbReference type="SMR" id="X0CFC3"/>
    <dbReference type="eggNOG" id="KOG3401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093240_0_1_1"/>
    <dbReference type="OrthoDB" id="1688503at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000009">
        <property type="entry name" value="60S ribosomal protein L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_A">
        <property type="entry name" value="Ribosomal_uL24_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK93100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="15299" checksum="3D8D60F212CB714A" modified="2014-05-14" version="1">MVKVSPIVSSSRRKSRAAHFKAPSDQRRVIMSAPLSKELREKYNVRSIPIRKDDEVTIVRGSNKGREGKITSVYRLKYVVHVERVTRDKANGQSVPLGIHPSNVVITKLKLDKDREDILARSKVGRELAANNKVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CG25</accession>
    <name>X0CG25_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13998</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658425">
        <property type="protein sequence ID" value="EXK81582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CG25"/>
    <dbReference type="eggNOG" id="ENOG502RYF5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044619_0_0_1"/>
    <dbReference type="OrthoDB" id="3466836at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF27">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="40"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="326" mass="35498" checksum="AA0F7B7DB53B6EAF" modified="2014-05-14" version="1">MADQATLKFDFIRLETKPSAQLSYSFTASTATKPTNPALIVFVNGLGAPQAGWIATMNKLKELSPQGLPAMLTFDRFGQGQTTDRDPNDEGAADPTHAHDCMAVVRDIRQLITQILKERLSIDNPDSTKLLLIGNSIGCALTRLYAAEYPGTVAGALLLDSVLTDTDFVSVFPNPDSEGFDPASLPPGVTADNLRVAREETAKRFHPSVGSREGLSRKNLTQLLGHSDSPALPKVDGKDPYITVLGHDFNYFAERTGTDFNIPGETVQAYMNTYWHHYNEGLAKLTSSERSEGPIQVPNAGHFLQLDNPGFVAGKLHDMLQKLAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHB5</accession>
    <name>X0CHB5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase M20 domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_13639</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK81997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHB5"/>
    <dbReference type="eggNOG" id="ENOG502QQPD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031812_1_2_1"/>
    <dbReference type="OrthoDB" id="6119954at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05672">
        <property type="entry name" value="M20_ACY1L2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.360:FF:000004">
        <property type="entry name" value="Peptidase M20 domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017144">
        <property type="entry name" value="Xaa-Arg_dipeptidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF0">
        <property type="entry name" value="XAA-ARG DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037226">
        <property type="entry name" value="Amidohydrolase_ACY1L2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="3">
        <location>
            <begin position="183"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK81997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="414" mass="44968" checksum="2D8DC86FC64818EB" modified="2014-05-14" version="1">MSSNEQLYEKISKSVAQHEQDLADICKKIHENPEFNYKEFKAHDNICDLMHRLGYNVKRSAYGIQTSFEVESGQNGKLIVFNAEYDALPGLGHACGHNLIATSSIAAFIATAETIRSLNIPGRVRLLGTPAEEGGGGKVHLIKAGAYEGVDACLMAHPTGKLSPQGEKNIDGVSAARSSARRQMKVAFTGQNAHAGNTPWHGKNALDAVVSSYVNISLLRQQIQPTERIHGVIRNGGTEPNIIPDSTNLEYYLRAAGADQIKELTGRVEACFKAGAIATGCEVKCSCESDQDYMELRPNLSMSNEFTKHMQAFGRDYIGDANQPPMGASTDMGNVTYCVPGIHPMFAVGTQDPMIQPHTPKFAEAAGTREAFERALDCAKGLAATACEMLLESGLMDQARDEFKRDVEPIGYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHD4</accession>
    <name>X0CHD4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_13658</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK82017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHD4"/>
    <dbReference type="HOGENOM" id="CLU_014819_2_1_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF16">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152143" description="Carboxylic ester hydrolase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK82017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="580" mass="63246" checksum="1A1D8B4CC6926924" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CID6</accession>
    <name>X0CID6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658415">
        <property type="protein sequence ID" value="EXK82337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CID6"/>
    <dbReference type="eggNOG" id="ENOG502RS7B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046066_1_3_1"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF11">
        <property type="entry name" value="ESTERASE_LIPASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="262" mass="28122" checksum="AFF4FDDEDCE207EC" modified="2014-05-14" version="1">MSSTQKPTILLVHGAWHGSWVWKYQIPELESLGYTTQNPDLPSVSGVAGKTQLDDAAHVRSVLEPLLAEAKQVVVLAHSYGGPIGCGAITGLSVAERARNNLPGGVLGFINLCGYIFPGGMDQGAVIRSLGGLPYVNWDNPSPGLFVAKDPGSLLYRPDVSDEQAQWALSQLQPQSMAANMGIVPPQAWQEESYKGRLAYIKATEDAVIPLSDQESMIVSSGGSEAWNTHVLEGSGHSPQISRPREVAQAVHSLIQDFQTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIS5</accession>
    <name>X0CIS5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Mitochondrial fission 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_04288</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the FIS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIS5"/>
    <dbReference type="eggNOG" id="KOG3364">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="421154at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12212">
        <property type="entry name" value="Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000179">
        <property type="entry name" value="Mitochondrial fission 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016543">
        <property type="entry name" value="Fis1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033745">
        <property type="entry name" value="Fis1_cytosol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028058">
        <property type="entry name" value="Fis1_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247:SF0">
        <property type="entry name" value="MITOCHONDRIAL FISSION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14852">
        <property type="entry name" value="Fis1_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008835">
        <property type="entry name" value="TPR_repeat_11_Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 12" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK94096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="153" mass="17191" checksum="ECE1B3FEC16268BE" modified="2014-05-14" version="1">MVTELPYALDAETPLNASELNVLKAQYEREGEMVGIQTKFNYAWGLVKSNQRNDQQLGVRLLSDIFRISPERRRECLYYLALGNYKLGNYGEARRYNDLLLDKEPANLQASNLRQLIDDKVAREGLMGVAILSGVGVAAGVVGAFILRNARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIY2</accession>
    <name>X0CIY2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NAD-dependent histone deacetylase SIR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_04483</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIY2"/>
    <dbReference type="eggNOG" id="KOG2684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046970">
        <property type="term" value="F:histone H4K16 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF9">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="157"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="328"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="331"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK94390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="487" mass="54618" checksum="C085D9167BD80C0F" modified="2014-05-14" version="1">MYTKKGNGRTVALSKRKAQPNALDKLGDNPTEDEIKTAEANVALAELEERVADVRESWETDSLFEDAFDELNADNTVAINDPKVCTPEEASRLRRELREYGPTVFCQRTVDAGHYTARKLLSAFGIRPPPFLEGQPDDAYFSLLSLAITRELSKRAKLLRHNTVDDAVDLITKSNNIILITGAGISTSLGIPDFRSKGTGLYSKLEHLGLSDPQEVFDIGVFRQDPTIFYSVAKDILPSTDRYTPTHKFIAMLHEKGKLLTNYSQNIDNLEVKAGVPKDKLIQCHGSFGTATCVQCGYKCPGEAIFPEIKADKIPRCPRCIQTLRTTGGAPKRKRSAGTEKKRRRWSADSSDESEYDIPSAGVMKPDITFFGEALPDEFSRRLTEHDRDKVDLVIVIGTSLKVTPVSEIVSWLPAHIPQIYVSRQAVNHINFDIDLLGDCDVVVSELCRRLRWPMVHDMVPKNQKVEVRTEPGYKSRHVFEEQKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJ50</accession>
    <name>X0CJ50_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Isocitrate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_06715</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Can also use Mn(2+) ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJ50"/>
    <dbReference type="eggNOG" id="KOG1260">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019214_2_2_1"/>
    <dbReference type="OrthoDB" id="4078635at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.850:FF:000001">
        <property type="entry name" value="Isocitrate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631:SF3">
        <property type="entry name" value="BIFUNCTIONAL GLYOXYLATE CYCLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="ISOCITRATE LYASE/MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="8 10 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="106"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="216"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="432"/>
            <end position="436"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK91298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="546" mass="60669" checksum="22A04FAE4D8C0D14" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKC9</accession>
    <name>X0CKC9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKC9"/>
    <dbReference type="HOGENOM" id="CLU_2671120_0_0_1"/>
    <dbReference type="OrthoDB" id="5046145at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="75" mass="8530" checksum="5F8A41E35B3070AC" modified="2014-05-14" version="1">MGKCLSRPERHDNLPKRLYPANTPDNEQPSVYSHPNAMLNPNNAARNTTPHAKATTSTKQSPRKRHPHHGNRETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CL24</accession>
    <name>X0CL24_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like 1-activating enzyme E1A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_03817</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CL24"/>
    <dbReference type="eggNOG" id="KOG2014">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002556_4_2_1"/>
    <dbReference type="OrthoDB" id="1708823at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01492">
        <property type="entry name" value="Aos1_SUMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF162">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="8">
        <location>
            <begin position="121"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="523"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="529"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="549"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK95135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="572" mass="61442" checksum="66B1069D200F6D0B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMT7</accession>
    <name>X0CMT7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F-type H+-transporting ATPase subunit epsilon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ATPase epsilon family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMT7"/>
    <dbReference type="eggNOG" id="KOG3495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_187039_0_0_1"/>
    <dbReference type="OrthoDB" id="269124at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12153">
        <property type="entry name" value="F1-ATPase_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1620.20:FF:000003">
        <property type="entry name" value="Mitochondrial ATP synthase epsilon chain domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.20">
        <property type="entry name" value="ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006721">
        <property type="entry name" value="ATP_synth_F1_esu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036742">
        <property type="entry name" value="ATP_synth_F1_esu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448">
        <property type="entry name" value="ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448:SF0">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04627">
        <property type="entry name" value="ATP-synt_Eps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48690">
        <property type="entry name" value="Epsilon subunit of mitochondrial F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="72" mass="7960" checksum="26EC9B0445D991B1" modified="2014-05-14" version="1">MTAAWRAAGLTYNRYLAIAARVVRRSLKEDKRIAAERRGEMDLRFSKWQNGKQGEPKNLAAANAAIAAENAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMU3</accession>
    <name>X0CMU3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Azaphilone pigments biosynthesis cluster protein L N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMU3"/>
    <dbReference type="eggNOG" id="ENOG502SICT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032923_0_1_1"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="426" mass="46805" checksum="384B5CA48C805240" modified="2014-05-14" version="1">MADGLSVASGVLALVTFAFQSSTVLYKTVRSFKTQDANARALKTELNDLTGVLHSLLETVTNYPEINFDSLELPLLRCGKTCEEYGKLIARCTKHSNGTRPSFRDWIGQQYLKGDITDFRDMLAGYKSTINIALANANITITAVTRNVIDEYKDMIDDTTADLQRHMQRLDERARSLAIPPAESVESDSTDWLALFEEKESTRKGLQICTELSLHIEALESTSSENPQFSKQPSADKYIKSSLSSAKSSISTLESRLRSHGNEIDKRMDAMKLKTDLSEDDINELAQLRETKESIHQCMNVVAHAGEDLARERANVFEDITMADNAYGITVSTVKDLVFARRVNVQGQARYVGGQIDEASYNATITALTDLDRGSAQYGGRDITLVSSKDEAAKKPVTSQAFLDRHGPGVKLDPSGVSAKPSGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNB2</accession>
    <name>X0CNB2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_03157</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNB2"/>
    <dbReference type="eggNOG" id="KOG1963">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005417_0_1_1"/>
    <dbReference type="OrthoDB" id="4096at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000234">
        <property type="term" value="P:positive regulation of rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053826">
        <property type="entry name" value="WDR75"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23869">
        <property type="entry name" value="Beta-prop_WDR75_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="361"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="887"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="887"/>
            <end position="917"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK95940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="962" mass="104437" checksum="BD04EB401E19A578" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNY7</accession>
    <name>X0CNY7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNY7"/>
    <dbReference type="HOGENOM" id="CLU_3377091_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="38" mass="4336" checksum="CEAD3B768C4075D7" modified="2014-05-14" version="1">MAFRLYQGQNGIACNSALTGWLYPYESRNSYNEAHTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CP22</accession>
    <name>X0CP22_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CP22"/>
    <dbReference type="HOGENOM" id="CLU_293205_0_0_1"/>
    <dbReference type="OrthoDB" id="3437384at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="767"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="976"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="435"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="691"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="777"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="982"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1037"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1037" mass="115628" checksum="C0DC7E46341B714A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQX9</accession>
    <name>X0CQX9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein SGT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02259</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SGT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQX9"/>
    <dbReference type="eggNOG" id="KOG1309">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039532_3_1_1"/>
    <dbReference type="OrthoDB" id="1898560at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06466">
        <property type="entry name" value="p23_CS_SGT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007699">
        <property type="entry name" value="SGS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044563">
        <property type="entry name" value="Sgt1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45862">
        <property type="entry name" value="PROTEIN SGT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05002">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51048">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="233"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="SGS" evidence="3">
        <location>
            <begin position="386"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="435"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK96850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="469" mass="51569" checksum="7806CEB9044D398C" modified="2014-05-14" version="1">MSHITLAQQGLAAAEARNWDEAIEKLSTALKASQNPAWLVARSKALINKKRFQEALDDANLAWHTAYQRNKRPLLIDAHYRRAVAYFRLGQYANADACCVYAMRLVKGFPAVEKEDPAKKNTDENGFYKVTLKDAQEESKTDDINKSQGGAAGALGAQGNDVANAKEWRIASTLRMQILFAMDKLPEDDPARKLTTANKPELKELSDVGSKKAETKESAAATQTASKPTVPADTPVRLQEFQNDTTMTVSIFSKGVNKEKLQVQFSPKSAHLDSIIWPSGDEKPFALDLWGEIDTEASTYRVTPNKVELALKKKTPGKWAQLKGEAGDSAPDAAAAEEAEKLKVLKDARKKAMDNAAAEAPAQEKPTDSTEAKEKTPAAQDSSKPAYPSSSRTGPKNWDTIGDDIDSDEEKDVNVFFKKLFKDASPEQQRAMMKSFTESNGTSLSTDWDDVKNRTVETVPPEGVEAKKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRU5</accession>
    <name>X0CRU5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10856</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRU5"/>
    <dbReference type="HOGENOM" id="CLU_013985_32_1_1"/>
    <dbReference type="OrthoDB" id="9975416at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051016">
        <property type="entry name" value="Diverse_Substrate_AcTransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545:SF42">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545">
        <property type="entry name" value="DIAMINE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="153" mass="17957" checksum="C55F67441DECE26C" modified="2014-05-14" version="1">MSSASYLIEKPVRSDYEEWSKLFRAYIDYYKSKIDEDQYARTFDRIIEEKNGLQALVVRQVRGEEKKLVGIAHFFPEQTPWSEKEILLLNDLFIDPEVRGEGLGRKLTQAVADVGREKGFMRVQWVTKHDNTAARKLYDTLAESQFVQYRMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSG2</accession>
    <name>X0CSG2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="16">ATP-dependent metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_04999</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSG2"/>
    <dbReference type="eggNOG" id="KOG0734">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_9_0_1"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.760:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000175">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FTSH 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048438">
        <property type="entry name" value="Yme1-like_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21232">
        <property type="entry name" value="Yme1-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 16" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 16" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="374"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="780"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="805"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK93799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="824" mass="89854" checksum="03BF2DE0D75F3016" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSX5</accession>
    <name>X0CSX5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chromatin structure-remodeling complex subunit rsc9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_04503</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSX5"/>
    <dbReference type="eggNOG" id="ENOG502QVTM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008152_1_0_1"/>
    <dbReference type="OrthoDB" id="338531at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.60:FF:000021">
        <property type="entry name" value="Chromatin structure-remodeling complex subunit rsc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052406">
        <property type="entry name" value="Chromatin_Remodeling_Comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003150">
        <property type="entry name" value="DNA-bd_RFX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970:SF14">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51526">
        <property type="entry name" value="RFX_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ARID" evidence="6">
        <location>
            <begin position="16"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="RFX-type winged-helix" evidence="7">
        <location>
            <begin position="638"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="275"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="225"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK94423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="938" mass="105904" checksum="D036764E6D751E01" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTE8</accession>
    <name>X0CTE8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979325">
        <property type="protein sequence ID" value="EXK85762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTE8"/>
    <dbReference type="eggNOG" id="ENOG502T64E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107684_1_0_1"/>
    <dbReference type="OrthoDB" id="4848529at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16572" checksum="DEB60E9DCC499B0E" modified="2014-05-14" version="1">MSDAAVKPNAWTDEAKNELLLRIIAQLKPEGKSINWSEINMEGRTVKSLQNQWTFFNKKLEAFKTQSNDGSTPSTPAKKATSARKRGPKAKKVAPDDDEVYESPKVTPRKRRAPKTPESDSKAVKKEPSEAVVKDEEMEDDRDVDGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTL3</accession>
    <name>X0CTL3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_02682</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTL3"/>
    <dbReference type="eggNOG" id="ENOG502QQUM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6019893at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032483">
        <property type="term" value="P:regulation of Rab protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00029">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005112">
        <property type="entry name" value="dDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051696">
        <property type="entry name" value="DENN_Domain_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005113">
        <property type="entry name" value="uDENN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296:SF21">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03455">
        <property type="entry name" value="dDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03456">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00801">
        <property type="entry name" value="dDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00800">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="UDENN" evidence="5">
        <location>
            <begin position="247"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="4">
        <location>
            <begin position="893"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="85"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="706"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="794"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="749"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="794"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK97511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1158" mass="127709" checksum="11965C2E7C2443E5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTX0</accession>
    <name>X0CTX0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_02921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTX0"/>
    <dbReference type="eggNOG" id="KOG0773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020539_0_0_1"/>
    <dbReference type="OrthoDB" id="10056939at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="227"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="229"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK97895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="601" mass="66600" checksum="6A8C381FDAFD4F30" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU15</accession>
    <name>X0CU15_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phosphate:H+ symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_02959</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU15"/>
    <dbReference type="eggNOG" id="KOG0252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_46_14_1"/>
    <dbReference type="OrthoDB" id="433512at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17364">
        <property type="entry name" value="MFS_PhT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004738">
        <property type="entry name" value="Phos_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00887">
        <property type="entry name" value="2A0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="511"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="54"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="539"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK97940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="567" mass="61285" checksum="7545E4044F7DC281" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU60</accession>
    <name>X0CU60_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_03650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU60"/>
    <dbReference type="eggNOG" id="ENOG502QSY4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014304_2_0_1"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031930">
        <property type="term" value="P:mitochondria-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN GUN1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936">
        <property type="entry name" value="PPR_LONG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="609"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="645"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="645"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="657"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK94853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="746" mass="85573" checksum="E1D488CAC5E2D8D1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CW32</accession>
    <name>X0CW32_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CW32"/>
    <dbReference type="eggNOG" id="ENOG502SWSC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046442_0_0_1"/>
    <dbReference type="OrthoDB" id="4174112at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022190">
        <property type="entry name" value="DUF3716"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12511">
        <property type="entry name" value="DUF3716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="303" mass="32860" checksum="B69EDE6456C24C12" modified="2014-05-14" version="1">MGKMKAGRSTRRHTPLPNTSTRSSNRIAAKKQTKGTKQAGSSQEKVPSAPHEPASSQETLKNSTDSSNQNNFSSFSSYNTNDHSAEQVEGTLTLAHRNPQVHGTGVTSSNPSNNTVGSDTPQLTAGDVALEIYGSRILIDSTLGKKLAGEASLRPIRQRRSDMVLNMERRSNVEAFLAHLTGVQVSRSCKNCSKGHGPWSECIIYDGQMCGSCTNCWFNASGSRCTFHENNQNSIYAPAPLYHPQSAGMPTQPFQYAQLNPQALPQGILPMNREATASLYVAPQMRNQFALRIFQSLGIGSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWF5</accession>
    <name>X0CWF5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWF5"/>
    <dbReference type="HOGENOM" id="CLU_049633_3_0_1"/>
    <dbReference type="OrthoDB" id="10034502at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013744">
        <property type="entry name" value="SidJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591:SF7">
        <property type="entry name" value="DUF1749-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591">
        <property type="entry name" value="UPF0613 PROTEIN PB24D3.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08538">
        <property type="entry name" value="DUF1749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="314" mass="34340" checksum="B313D346AAD1C1F4" modified="2014-05-14" version="1">MSPSGPFQVTVHPFESKCRSSAAYEIGLTSAPNAIVFIGGLTDGPHTIPYTRLLAQRLEEVKELGFSVIEFRMRSSFSGFGTSSLSNDVEDISALVKYLRGIGKEKIVLFGSSTGCQVIYSLVATFYISSDQLQDCIEYANYAKHNNEPVDGFVMQGPVSDRETLDLIFPDPQPSLDLAAKMISEGKGGDCMPFDMIPAVLGAPISAYRFQSLASKGGDDDYFSSDLPDDVIERNWSRFNKPVLVLHSAEDEFVPERIDQAASNKKYKALNSAVSRLSGLIPGASHTVDQPQAQEWLSKTVIEWLKTEVTSSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWJ3</accession>
    <name>X0CWJ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWJ3"/>
    <dbReference type="eggNOG" id="ENOG502SJRE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_441481_0_0_1"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="21"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="2">
        <location>
            <begin position="236"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK98865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="634" mass="72302" checksum="AFAAC2003EC77449" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXD7</accession>
    <name>X0CXD7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXD7"/>
    <dbReference type="HOGENOM" id="CLU_1917131_0_0_1"/>
    <dbReference type="OrthoDB" id="4971255at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="132" mass="15040" checksum="64C3BC55344C953E" modified="2014-05-14" version="1">MGHLSQIEAVMEAYDDILYHYPDDGEDTLNMPKKEVIVKQKADFNYWTIHSGVCMPEIDLEHEFEREAIKGLDDFIETAHKLERLYQEDPSPNVIWLADEYVASLSQRLSQLAHTFGVLVPSLQDTGTASGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXH4</accession>
    <name>X0CXH4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Actin-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXH4"/>
    <dbReference type="HOGENOM" id="CLU_495253_0_0_1"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="58582" checksum="1343CA9E10C5D856" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXQ7</accession>
    <name>X0CXQ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein ERB1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Eukaryotic ribosome biogenesis protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ERB1</name>
        <name evidence="10" type="ORF">FOQG_09472</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat BOP1/ERB1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXQ7"/>
    <dbReference type="eggNOG" id="KOG0650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011390_0_1_1"/>
    <dbReference type="OrthoDB" id="5571054at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000061">
        <property type="entry name" value="Ribosome biogenesis protein BOP1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03027">
        <property type="entry name" value="BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028598">
        <property type="entry name" value="BOP1/Erb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012953">
        <property type="entry name" value="BOP1_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08145">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01035">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BOP1 N-terminal" evidence="9">
        <location>
            <begin position="145"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="414"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="738"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK87232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="763" mass="85633" checksum="D7793AF4F48AA5EA" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY05</accession>
    <name>X0CY05_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_09171</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY05"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF10">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="76"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK87352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="536" mass="59196" checksum="36547D675B6AA731" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYE2</accession>
    <name>X0CYE2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYE2"/>
    <dbReference type="eggNOG" id="ENOG502SP3K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081631_2_0_1"/>
    <dbReference type="OrthoDB" id="3830579at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="25340" checksum="1BC76030C9ED9612" modified="2014-05-14" version="1">MTVTEVGCMGVKPNMNIMDHTTPEGKILTDAWNTVISKPGGPQRVYWGLESVEPSMVWCFFDFDSIEQHRRFAEEYGADAVKDIPKICTYGEFSKHIKMVPSSDVLESPLTEIILAFFPQDISEEKKEALSSKIQEILRQAFPGEARVAHAWGVENDFPARGEDGQPRSVLMGFVGLSHSEAWGTYRQTDAWKEALSSIERLEGCTSIYSFAIRSQHLERLERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0I2</accession>
    <name>X0D0I2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein RCR2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_00505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0I2"/>
    <dbReference type="eggNOG" id="ENOG502S8F1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131051_0_0_1"/>
    <dbReference type="OrthoDB" id="3556830at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020999">
        <property type="entry name" value="Chitin_synth_reg_RCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187:SF1">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12273">
        <property type="entry name" value="RCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXL00276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="19206" checksum="8616AC2719F97AA0" modified="2014-05-14" version="1">MAPTEDVFARDYYRCSYGWNWNGRRCVRNNWSYWGRWVLAGIVIFFFVLFLFCCLFSRRRKRRGVKPVYGTGWMAAKPWGNNNNNHQMYNYGNQGGYNQGYQQNNGGYGAPPPPPAYGQQQQPQYTGTTFNTNDGYYGQGQYSGVQQPQGTYQRDGAYSPPAGPPPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0K7</accession>
    <name>X0D0K7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_02088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0K7"/>
    <dbReference type="eggNOG" id="ENOG502SVKU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1750362_0_0_1"/>
    <dbReference type="OrthoDB" id="3682102at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="152" mass="17013" checksum="2EC585580A851E8B" modified="2014-05-14" version="1">MATKANVPKAPSKTIEEFLHRHPQVHTGTAAKAELDHLHEHGDTFCVINKLYDNAILHKDYDPDSLKLIFAFAYVNDEQAMANYAEDAGEDDSVLCDCEVGREEGPDHHLHEFVRATEPDCEVHKGEELDPGCKDCWPVYCGSNCRGVEGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0D231</accession>
    <name>X0D231_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D231"/>
    <dbReference type="eggNOG" id="ENOG502SVPD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022039_0_0_1"/>
    <dbReference type="OrthoDB" id="5423493at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="594" mass="65179" checksum="BCF38F780A0AE6D3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2M1</accession>
    <name>X0D2M1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2M1"/>
    <dbReference type="eggNOG" id="ENOG502T4D2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140460_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="144" mass="15892" checksum="09ECF7E9ED276286" modified="2014-05-14" version="1">MPYILPENHTYLPSPYKLRNQPIMAPSVYILLQRDTESNVTVTSVFLDLQDANAALLHTAQEAGVDPASAKPADGDAKDSLTKAPLRWEAADGTAAWVERHTVTNRKVQAPGAEKPGLKRNDSRLYINDDDDIIEVADHDGHYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3E2</accession>
    <name>X0D3E2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-1-phosphate guanyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">GTP-mannose-1-phosphate guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Translation initiation factor eIF2B subunit epsilon</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">eIF2B GDP-GTP exchange factor subunit epsilon</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_02773</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3E2"/>
    <dbReference type="eggNOG" id="KOG1461">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012507_1_0_1"/>
    <dbReference type="OrthoDB" id="424572at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04197">
        <property type="entry name" value="eIF-2B_epsilon_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05787">
        <property type="entry name" value="LbH_eIF2B_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11558">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000066">
        <property type="entry name" value="Translation initiation factor eIF-2B subunit epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035543">
        <property type="entry name" value="eIF-2B_epsilon_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051956">
        <property type="entry name" value="eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044123">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="12">
        <location>
            <begin position="532"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="504"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK97644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="721" mass="79931" checksum="D9D6EED61BC5EE52" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D3J2</accession>
    <name>X0D3J2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_07887</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D3J2"/>
    <dbReference type="eggNOG" id="KOG3030">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021458_2_0_1"/>
    <dbReference type="OrthoDB" id="8907274at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF154">
        <property type="entry name" value="PAP2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G09730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="128"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="261"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="386"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="402"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="436"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK89212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="470" mass="52141" checksum="77768E2C72C030C0" modified="2014-05-14" version="1">MHSYYKMGDSGLGTLSGGLRGRRFPIRLILSYLFDWIICFVFVGIGGWLDRVAPAKRPFSLVDPNISYPFAEHELVPAYLLFVLAIGVPFVIVAVVSLIFVPGPTVPKGTPKTLIWQRKLWELHVGVLGLVLSLTLSWFFTSSMKNLFGKPRPDLLARCDPDWKNIDKYVVGGFKWQSMTGQLVSADICQQTDKYKIDDGFRSYPSGHSSSAAGGLIYASLFMASKFAVTIPFVMPSAAAVAGAASHAAFPSRIHTGSVVDPYEPSRARGPDGSFSSVPTKERAGQDNAKVQSLRRQAAAPPIYLLALGLLPFGVSIFIAGSRWHDRRHHGFDILFGYLMGLVASIFAFRYYHLPIRAGAGWAWGPRSDERAFWAGVGRQGYAGTDEELGVYSPQRDVGHSGDTSYPPMTSALAQRNVRQNTDQEPRPSQNFQDVELQRMDDSDRLENRFPDERFTENRYGDAHHAENRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4B2</accession>
    <name>X0D4B2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein yneE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_07592</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4B2"/>
    <dbReference type="eggNOG" id="ENOG502S81E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029790_1_0_1"/>
    <dbReference type="OrthoDB" id="1368at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK89497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="50854" checksum="3D472F1744BCD15D" modified="2014-05-14" version="1">MSDAGRETPVEMKPLPQAQTRQNFSGLDTPPNQQYLPSPSPPVSDGMNDSNYFSGPRDLRGHSKWPLILQLHGSIMPSLIIPLFLVACWSTAITVISKKVHDLSVNSVLLTILGFVVGLSLSFRSSTAYERYAEGRRYWGMLATASQTLGRIIWIHASDTGADGQDTCELLVKKLGALKLIAGFAVALKHTLRFEHCASQPDMQPYIAHLDTFSGRTTAMPKRRVTNFKQVAGEYLGLSFAQSDPRKHLKRAEEHQGNLPLEILNHLAISVDCLVANKQLSVAIHQTVAYNHITMLNDVAVGCDRVLNTPLPIAYTIAISQITFVYVMLLPFQLTGPLDWIAIPATITAAYIIFGLLFIGQEIENPFGRDVNDLPLETFCDQIATDLDITASFDRRGADHFLLNGTPLYPVSAALGNAWMDSSEEKMREAIKTKPHVLFNWRRQSTRGNTTKERDGNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0D7Z0</accession>
    <name>X0D7Z0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcriptional activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D7Z0"/>
    <dbReference type="eggNOG" id="ENOG502S8VT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="21557at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="39763" checksum="C6E6CC348B84B46F" modified="2014-05-14" version="1">MNAGTGRAGVISAPDDAAPMDKLAHAVLDDVLYNVLSDLLMKTHREEKTARATTAAIRIEKLASDASDSSTPDSKPDVRIETDAAIYEDGKVLLKGNPLKTTAEILCPRCHLPRLLYPTDGKGAQKPDPGVIYCKKHPYIDKPGCDIYGQSWVAPGPGRGKKKKDMEKNNTDSPTPEQRPPNVLSFPSATCSKCKRCILVTRLNNHMGSCIGNSGRNASRAAAQKLSNGGSQNDTTPPSSQKATPAPGSRAASPKKRDASDEEEDSENSHKKKKLKPTSSVTKKVILKTKPNLKKDKPKGLSSLSQEQKADYSNSESVEVAPKKVVSKGISPVKKLKMNKPPLGSPKPKPSLIREATGESESSDTLSSPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0D931</accession>
    <name>X0D931_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-serine ammonia-lyase</fullName>
            <ecNumber evidence="5">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_00387</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="5"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D931"/>
    <dbReference type="eggNOG" id="KOG1250">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_3_1_1"/>
    <dbReference type="OrthoDB" id="7773036at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06448">
        <property type="entry name" value="L-Ser-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000040">
        <property type="entry name" value="L-serine dehydratase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF2">
        <property type="entry name" value="CATABOLIC L-SERINE_THREONINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="11">
        <location>
            <begin position="13"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXL00074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="341" mass="36433" checksum="87DDC31FC7EE853F" modified="2014-05-14" version="1">MGSLGSDAKLPWIRTPCLLNPQLSRVAGCNVYLKLENLQPSGSFKSRGIGNLMTQAAAAATGPVHFYCSSGGNAGLACATSALSLGQKATIVIPTIITELMKGKLLDLGVEVHQKGRNWAECDKYMREELLANDPMGIYVPPFDDPRVWDGAATMVDEIRDQLEEPIEGIVCSVGGGGLINGLMQGVEGRPWQDKKPAVVAVETKGADSLNASVLAKEHVTLPEMTSIATSLGATRVSEQTWKWSQHSSETMKSLVVSDADAAISAVRFADDGRHLVEVACGAALAPAYRGDLRRVLGQGMSDEEWGKKNVVIVLCGGSNVTLGMLNEYRDKYRGESSIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0DCF4</accession>
    <name>X0DCF4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DCF4"/>
    <dbReference type="eggNOG" id="ENOG502T6ZE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_172699_0_0_1"/>
    <dbReference type="OrthoDB" id="5089392at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL01204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="94" mass="10285" checksum="195D631412E63101" modified="2014-05-14" version="1">MAFGSSRTRNSSEEQRGRSTEPIPLMESKQRTNSYSSEFSTQSTASSTTKASRSWFKAAPQPVNNVTYCGRHSSQFLFGGPSLADLARAMLGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DDD0</accession>
    <name>X0DDD0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Exonuclease V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_05653</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EXO5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DDD0"/>
    <dbReference type="eggNOG" id="KOG4760">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="354769at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045145">
        <property type="term" value="F:single-stranded DNA 5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019190">
        <property type="entry name" value="EXOV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464:SF4">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09810">
        <property type="entry name" value="Exo5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="39"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="112"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="269"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK92547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="536" mass="60152" checksum="3C1FA87BA342C0B4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0DGL9</accession>
    <name>X0DGL9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Spt20-like SEP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DGL9"/>
    <dbReference type="eggNOG" id="ENOG502RKFS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004682_0_0_1"/>
    <dbReference type="OrthoDB" id="1932706at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021950">
        <property type="entry name" value="Spt20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046468">
        <property type="entry name" value="Spt20-like_SEP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13526">
        <property type="entry name" value="TRANSCRIPTION FACTOR SPT20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13526:SF8">
        <property type="entry name" value="TRANSCRIPTION FACTOR SPT20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12090">
        <property type="entry name" value="Spt20_SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spt20-like SEP" evidence="2">
        <location>
            <begin position="125"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="853"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="965"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="553"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="965"/>
            <end position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK93627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1006" mass="110654" checksum="B73B34622D5DCEC2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0DH84</accession>
    <name>X0DH84_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DH84"/>
    <dbReference type="HOGENOM" id="CLU_2776026_0_0_1"/>
    <dbReference type="OrthoDB" id="10290366at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK93802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="69" mass="8043" checksum="1F8ABF5C8F493424" modified="2014-05-14" version="1">MHCRYVQHLSKRIEDLALIGIIEVITDMSECFADPISTSHRTIWPEQYPEQDKPVSEQTYQKFLTTCNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0DJC5</accession>
    <name>X0DJC5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DJC5"/>
    <dbReference type="HOGENOM" id="CLU_1090048_0_0_1"/>
    <dbReference type="OrthoDB" id="27483at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF7">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK94507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="255" mass="29679" checksum="708AE4941BD6CADE" modified="2014-05-14" version="1">MRAVTFACPLDLKNDVFQQPKTPEFDLTAMSWYSDVTHEVERLTSGYRLVLPYKLFATGEDELWASIFFQQTKDLKSILAKFRTDLPKVGKLLYPLEHLYTESSLCLRNLKGRDRSIGRYLNEICSEACFYFMFGQTTHFQVGIDDCDEYQDQTTLRTLYNLNGDQLSSELVLNLENFLDYDIGREAPDIEDEGGLFGKAEEPRVFHYHKTVACLMPKEYLHQLCSNRPSYRPSCTITEDYFDRNGVSRSFEKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0DKC6</accession>
    <name>X0DKC6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="3">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_03638</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="3"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK94817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DKC6"/>
    <dbReference type="eggNOG" id="KOG1567">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10248373at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.620.20:FF:000004">
        <property type="entry name" value="Ribonucleoside-diphosphate reductase subunit M2 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="entry name" value="Ribonucleotide Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030475">
        <property type="entry name" value="RNR_small_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409:SF18">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00368">
        <property type="entry name" value="RIBORED_SMALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0215">Deoxyribonucleotide synthesis</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK94817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="409" mass="46446" checksum="272C388957BEF38B" modified="2014-05-14" version="1">MAAQITPSKQAASAIENFKMESPVKKLDFGAANKENEPLNKSLDTTDLKTKIVEEPKKEETKAAVAPGIKSEEADEPLLQENPQRFVLFPIKYHEIWQMYKKAEASFWTAEEIDLSKDLHDWNNRLTADEQFFVSHILAFFAASDGIVNENLVERFSGEVQIPEARCFYGFQIMMENIHSETYSLLIDTYIKEPAQRTYLFNAIETIPCIRKKADWAIRWIQDKDSSFAQRLVAFAAVEGIFFSGAFASIFWLKKRGLMPGLTFSNELISRDEGLHTDFACLLHSHLKGRASKQMIQDIITDAVTIEQEFLTEALPCALLGMNSDLMKQYIEFVADRLLVALGNEKVYKATNPFDFMENISLGGKTNFFEKRVADYQKAGVLHSATKKTEEDESPKGENGGDFTFDEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0DUE2</accession>
    <name>X0DUE2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7371 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02889</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502SRUH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002657_0_0_1"/>
    <dbReference type="OrthoDB" id="5385013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055795">
        <property type="entry name" value="DUF7371"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24086">
        <property type="entry name" value="DUF7371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937748" description="DUF7371 domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7371" evidence="3">
        <location>
            <begin position="1092"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="698"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="964"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="593"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="705"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="976"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1056"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1074"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK97852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1317" mass="131665" checksum="8AB2A89D248A61B2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DXR6</accession>
    <name>X0DXR6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DXR6"/>
    <dbReference type="HOGENOM" id="CLU_2073275_0_0_1"/>
    <dbReference type="OrthoDB" id="10273197at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="125" mass="14758" checksum="9AFE74DE416B6A7A" modified="2014-05-14" version="1">MEAHRSTTESREPWPPIVDECFRFQGSRPIFYMYVCHGKWSRERHMEQGRAFRTLPLSEPPGHDIVCKSVYGRHLAEYLERPYTHLEGIDWDFQALIEPIFLINSPKKDNSCCTLSRYLINLLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0E2L6</accession>
    <name>X0E2L6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E2L6"/>
    <dbReference type="eggNOG" id="ENOG502RZBG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032395_0_0_1"/>
    <dbReference type="OrthoDB" id="4463286at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXL00558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="432" mass="45927" checksum="96C0EE5EF8A60BE4" modified="2014-05-14" version="1">MSAAIAMAPSPAPHERFSNPELPAPSTSAATVGTSPSAQRSSLNLSTSHATTQSSTSSSPKAAGQGAKSSPSSASRSAGAPPRIIVKKEPASPSMTHTRPRPRKLDLSKNTPKSNQPTSARPMTARDGLAIQEVGIACLSPGFVTQDPVMKEQLQRSMSVREQQRHIIEARLHQQSAKGDGPDKDPVSQFAAKTPGMSRRNKAPGLSIVAPSHEQFANERVIQSAPLGHSFTGRQHPAPMTRHITNQPSNLSSTSHIHHIPATQTANRLPPISDVFGQGLSAHPDNAPQPQSLYPSGPSSRGPMTSPGHPPPPQAPTPGRGREYRSAEEAQQELAGGRPELLPKLVHYGGHQPPTPPSPAPGSRPVDASRSASTSRRRTRAEYEDGSPPLGHGPAPTRRGPFGAGRDSPETQRAKKEEFIRLCERAWDLFHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0B0D6</accession>
    <name>X0B0D6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980063">
        <property type="protein sequence ID" value="EXK75590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B0D6"/>
    <dbReference type="HOGENOM" id="CLU_104709_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="178" mass="20151" checksum="BF83911E066339BE" modified="2014-05-14" version="1">MAQTPSSPLNAATIAAATEGAEGGEKEPCIYAKTRSHSQQIKEAEQILELFNLLRTGSENQAVDSLRILRSHNDVENFLDIIKARRSQEKRTRERERAPISTSKLGIEYELMTRNVVMFPPLQTIESNVLKLVILHKIQAFSEIQFERIAYMLSHGLQFQAYTLQGGLEHRSSINGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B0I0</accession>
    <name>X0B0I0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI980001">
        <property type="protein sequence ID" value="EXK75625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B0I0"/>
    <dbReference type="HOGENOM" id="CLU_1102831_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="252" mass="28635" checksum="25A466EB9DC3232F" modified="2014-05-14" version="1">MIKVNDDTGTPEILGYDKGKYFETWVDFDSIDYDGNADLGGFPTKTMDQYGQPPAALHVSGELQPLETYLAPPSRFKNGQTLLILLYLLCPDNGSLFAHFAPSSLPALPSPKSWSHLQEYTVVSNEVFQKLKELNITLEGDCEISYASILHEDEMFLWLPKDNKLWCIPISCEELSRRSDCYLMFANEFATLERIVAKVKLGDKARNEARCVVALARKTDGAHLGYYCRQWYNAWISLGGRRLDYVTLLRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2I6</accession>
    <name>X0B2I6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_18933</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="KI979538">
        <property type="protein sequence ID" value="EXK76325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2I6"/>
    <dbReference type="eggNOG" id="ENOG502RY3D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_1_0_1"/>
    <dbReference type="OrthoDB" id="4849160at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF34">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936117" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="13">
        <location>
            <begin position="20"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="14">
        <location>
            <begin position="20"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="245"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK76325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="344" mass="35721" checksum="3FF1352991B9C20A" modified="2014-05-14" version="1">MSFKVAATLAGAFASVALAHGTVTGIKVDGTYQPGYDLSSYYKAQQGGEIPSIAAWSAENLDNGFVPPSDYGTSDIACHKKAAPGTSSLSVKAGGTVEFQWSAWPESHIGPVLTYVAKCAGKCTSADPATLKWVKIDAAGLDGTWAAADLIKNNNTWTTTVPETLAAGSYVFRHEIIALHGAGSKDGAQNYPQCFNIDITGSGTDNPEGTLTTELYTDSEPGILFDPYKGSTTYEIPGPALYGSASGTKPVVPDTPSNGTISTPAPAAPTPVAPTPVTPTSLVTSVAAAATQAAEVPSTEAPVAEEQDTEDGALPKTFTLDTFIDWLRSKNGGSKKARRHARQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0B2V7</accession>
    <name>X0B2V7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar calcium ion transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_18793</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH658716">
        <property type="protein sequence ID" value="EXK76465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B2V7"/>
    <dbReference type="HOGENOM" id="CLU_008721_2_1_1"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00846">
        <property type="entry name" value="caca2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF22">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 10" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="365"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="67"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="263"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK76465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="414" mass="43983" checksum="74C8232947C4EED0" modified="2014-05-14" version="1">MNSQSAASPLLDRVTASAPTNNYCSGAKRSLAHCWHIAKVTLLSNYVNFLLVMVPLGIIAGKMGWGSTAVFTLNFFAIIPLAAILSFATEEISMTLGDTLGGLLNASFGNAVELIVSIVALQRNEIELVQASMLGSILSNLLLVMGMCFLFGGIMHRGESGSGHEQAFAPATAQTACSLMTLASASLILPATLYAVLDQRSSNEKAQSILTLSHGTAIILLSLYVLYLVFQVRTHSNLFDPENQNDSSGEVEHVEPTLGPIAAIAVLAVTTLLITFCADYLVDSIDDFVKASGISRAFVGLILIPIVGNAAEHVTAVVVATRDKMDLAMGVAIGSSIQIALLVTPFLVIVGWITGYEMTLHFETFQTVVFAMSVLFVTCTVQDAKCNYLEGAMLIGLYIIIGLAFYSLPSSEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7H8</accession>
    <name>X0B7H8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658545">
        <property type="protein sequence ID" value="EXK78115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7H8"/>
    <dbReference type="HOGENOM" id="CLU_051367_1_0_1"/>
    <dbReference type="OrthoDB" id="5279008at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="436" mass="50442" checksum="EAF835AC5A11B84B" modified="2014-05-14" version="1">MATLLELPEVVIHSVAELLPVDDFFSLRLSCRRLNAMSLHAFIRVYFQTRYVMLEEHSLQTLISISQHETFGPAVRALGFCTEHLLEMDDEQSRDFFAFLEAGWGRGYPRGEEFEEEFEDESDEDLEMEEDDKEDFYDRVYRERLDDQKTLLLGHDIIYLAQAMTGLPNCKTLILTDARIPWGASRLKREVGSELSRGFHPDNVEDEQFVRRILQVMLSAVAKSELSVEKLDFYLGHVDEPKSVNPISLQLLDWPVYVSPIAWTLTSLTSLRLLISPFYKNNRAYGWEKRAMGFFDLFPQLSHFTLAFDDEFDNHTVFPIFSELLKIPQLRVMELARFAATAAELTKMLLRHQSTLEDITLREVKMNEVGSWTSVLSTVRDMPQFHSFTMKQCLIGDWFFTDVSDEIDEVVSIKDRGRIEELAAQIEMVSAEMAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0B946</accession>
    <name>X0B946_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658530">
        <property type="protein sequence ID" value="EXK78276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B946"/>
    <dbReference type="HOGENOM" id="CLU_000288_125_3_1"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="384"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="805" mass="91034" checksum="127E22DA9DB26E60" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B9Y9</accession>
    <name>X0B9Y9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979975">
        <property type="protein sequence ID" value="EXK75638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B9Y9"/>
    <dbReference type="HOGENOM" id="CLU_147510_0_0_1"/>
    <dbReference type="OrthoDB" id="5050147at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="172" mass="19636" checksum="7E5B0A2F726D14F4" modified="2014-05-14" version="1">MTRSEYTRIDKKRTLRRRIVDETYGPTKEVKVWERIKELVKAPDKSPNLYVQVPSSESIHRIDDSVTSHTLDSLSHAVESRVEPRTTNDRKEDNHISISIEFTHNHPCREDGEDEDLRCLWIPSSDDEEDGEAAHADAVSVTTWPGGLELYVLGLVMTGLLFAQKQMVMSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BA96</accession>
    <name>X0BA96_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secondary metabolism regulator LAE1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979860">
        <property type="protein sequence ID" value="EXK75733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BA96"/>
    <dbReference type="HOGENOM" id="CLU_010595_11_3_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17192" checksum="7215C8C5760C967A" modified="2014-05-14" version="1">MAATDGDVIVAPDDNDVADQDSSFGSETASSTTSLRSSILDYRHENGRTYHRYKDGKYNLPNDERENERLDLQHHLFLRTFDNNLGLAPPNLPGSNVERVLDVGTGTGIWAIEFADDHPEAEVKGSIQELKMLIADIIYRFSGSTFLPFSLACTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAC5</accession>
    <name>X0BAC5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979837">
        <property type="protein sequence ID" value="EXK75763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAC5"/>
    <dbReference type="HOGENOM" id="CLU_1026881_0_0_1"/>
    <dbReference type="OrthoDB" id="5234017at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="271" mass="29253" checksum="098BBCC07F893794" modified="2014-05-14" version="1">MAAPDQGQEEPSSLPATRPVSPLDHIALHDPPIQQQSLPDLRSDEGQQHRLNLEDIAASSHGPGRQLDEPCDIFEPISTAALSDTTQEVCQDAGLLQPHCDERANRTATPEKDMGAGLFGLSVSEQASGVAIFPPHLPSRELLPMNLMSKPRKTPEIYATEPFPSSPSIPHASSTDSAQPALLYALEQHAQVEMGRPYSNRPIIDAANSTTEERQQAQQSPSVVQSSNDASDAVGAVFFSRSIVPVSRQWTITAVTITVTLYSTIDDQTCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCQ6</accession>
    <name>X0BCQ6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cip1-like core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15499</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979343">
        <property type="protein sequence ID" value="EXK79945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCQ6"/>
    <dbReference type="eggNOG" id="ENOG502SH79">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071363_0_0_1"/>
    <dbReference type="OrthoDB" id="5313668at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048955">
        <property type="entry name" value="Cip1-like_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21340">
        <property type="entry name" value="Polysacc_lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936366" description="Cip1-like core domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Cip1-like core" evidence="2">
        <location>
            <begin position="23"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="240" mass="26036" checksum="3BEDB69D60349F6F" modified="2014-05-14" version="1">MLRQVALAALSVLPLALGQVAEDFESGWDKVAWPTYAPDCDQGGSVELDKTTAHSGKNSIKVTGGPNGFCGHKFFGTDAVPEGHVYVRTWMKTAKAFDDSHVTFITMPDSAQGKGKHLRIGGQSKIMMYNHESDDATLPDLSPDGIAASKNIPANTWQCLEYHLSPDGTIATWLNDNPVHGLVYKPNAPSSYAGGWARSKPKPKVQGVYFGWESYSGAVNTFWFDDIAIDSKRIGCAVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BD43</accession>
    <name>X0BD43_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979340">
        <property type="protein sequence ID" value="EXK80085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BD43"/>
    <dbReference type="HOGENOM" id="CLU_170493_0_0_1"/>
    <dbReference type="OrthoDB" id="5012364at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="114" mass="12798" checksum="6B21DFF948F84C60" modified="2014-05-14" version="1">MRSKLPNCLQPLFSPATEDMTLDINTLNNHPAKTNDLPTRQCHADDVTFVSTPAATEDRDTAKCPIDEPEKEDTIVPEPPGDIFISLFDIPINELHELGEPYYKLSDIRHEGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDM0</accession>
    <name>X0BDM0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658664">
        <property type="protein sequence ID" value="EXK76923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDM0"/>
    <dbReference type="HOGENOM" id="CLU_131601_0_0_1"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF9">
        <property type="entry name" value="L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="13"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK76923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="170" mass="18311" checksum="A09A530F348D3268" modified="2014-05-14" version="1">MDGANNLAPRPGVRGLQPWETVSLEIGGRVFEITATPCQHLPGGECIGFVLTCAKFGHSNGKSNAIYFSGDTVYVPQLAEIGNKFNIVVALINLGCAVAGLPTGPVQITMDAKQAAQLVRAIGAKIMVPMHFESWEHFTQKGPEVRKVLQEEGMEDKTVYVNLGEKTCLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE12</accession>
    <name>X0BE12_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658646">
        <property type="protein sequence ID" value="EXK77063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE12"/>
    <dbReference type="HOGENOM" id="CLU_002467_3_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK77063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="564" mass="63485" checksum="B3AC59DAF39F7C36" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEA8</accession>
    <name>X0BEA8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_15320</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658451">
        <property type="protein sequence ID" value="EXK80146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_27_5_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000055">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000066">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000838">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001854">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF269">
        <property type="entry name" value="ABC MULTIDRUG TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="507"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="921"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="968"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1069"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1106"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1146"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1180"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="295"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="645"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="932"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1249"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="600"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="611"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK80146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1495" mass="164583" checksum="035055095C78DFF6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFB3</accession>
    <name>X0BFB3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4-coumarate--CoA ligase-like 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_14680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658435">
        <property type="protein sequence ID" value="EXK80825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFB3"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_2_1"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="72"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="347"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK80825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="48008" checksum="3CBE328619F10203" modified="2014-05-14" version="1">MAKKAAEAAGLPPNSLVLIDSKDSSAVGGVSSFQSLLGYGTYSWERISDPKVLADKYVANVASSHSTKPDISLRPAVLNFSSGTTGLPKACEITHRNLVANAEQNLHLDRVARKRKNDPTFAANDVHCAFLPFYHAMGLITFCILNVKRGCTTVVMPKFDLKSFLSTIQDFKVTYLILAPPVVSMLVKSLLVCQYDLSSVKFLVCGAAPLQADVEKRLEALFSKTGARSRQGWGMSEATMSISIFGPDEFDPSHGSVGYLVANMQLQIIDENGKALGYDEEGEAILRGPNMFKGYYKNPAATKEAFTDDGWVKTGDIVKIDRTGLVTIVDRKKELIKVKGFQVAPSELEGHLLEHEGVLDCAVIRVLRNGQEHPQAHVVRKKPGATAESILSFMDKRLSPVKRITGGIVFTDAIPKSRSGKILRRLIKDGFASKDPSPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGK5</accession>
    <name>X0BGK5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4-hydroxyacetophenone monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_14317</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979335">
        <property type="protein sequence ID" value="EXK81265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGK5"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_7_1_1"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF4">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK81265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="651" mass="74730" checksum="061620F41BA69745" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGU1</accession>
    <name>X0BGU1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_14471</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979336">
        <property type="protein sequence ID" value="EXK81041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGU1"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062498_0_0_1"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF68">
        <property type="entry name" value="PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936927" description="Peptidase A1 domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="37"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK81041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="384" mass="41560" checksum="348F9A8564DAED9B" modified="2014-05-14" version="1">MGSVTRFASAVLATSTLLGAASAAVLDMPMVIKDGYKMVQVGVGKPEQDFLLLFDTGSASTWMIDSECATECPHYNKDRVGYNFTASSTGKYTGEDASIDYLGGKVAGPTVEERFEAAGLTWQSKFIAANESNWSSLAAAGFMGLAFGSIADGGATPVFETLMAEKKVDEPRFGIYYSKEDGDDTKGKPGKGLLTLGGSKEKEYVKGDLIDIPINTNLNDYDVWRSVLHSTTASTKGKNSSQTRSKVDLDVRVVFDTGASGITLPESKIVEVYESIGMNWTAILNGDHIPLCSEFTKDWSVAFEVGYYGDSRFLNVTGDQLALPGFANRDDACWPPMDSGAEGFALLGTRFLKNFYTVWDYGVFPEEAGFIRPTLSFGYLKEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHJ7</accession>
    <name>X0BHJ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 12">Adenylosuccinate synthetase</fullName>
            <shortName evidence="10">AMPSase</shortName>
            <shortName evidence="10">AdSS</shortName>
            <ecNumber evidence="10 12">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_14257</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="function">
        <text evidence="12">Plays an important role in the de novo pathway of purine nucleotide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10 12">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 12">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="10 12"/>
    <dbReference type="EMBL" id="KI979334">
        <property type="protein sequence ID" value="EXK81296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHJ7"/>
    <dbReference type="eggNOG" id="KOG1355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029848_3_2_1"/>
    <dbReference type="OrthoDB" id="10265645at2759"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046040">
        <property type="term" value="P:IMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.300.10:FF:000001">
        <property type="entry name" value="Adenylosuccinate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.170.10:FF:000001">
        <property type="entry name" value="Adenylosuccinate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="entry name" value="Adenylosuccinate Synthetase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="entry name" value="Adenylosuccinate Synthetase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="entry name" value="Adenylosuccinate Synthetase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002223">
        <property type="entry name" value="PRK01117.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="ADENYLOSUCCINATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846:SF0">
        <property type="entry name" value="ADENYLOSUCCINATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 10 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10 12" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="74"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="75"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="100"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="102"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="359"/>
            <end position="365"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="391"/>
            <end position="393"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="473"/>
            <end position="475"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK81296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="485" mass="53673" checksum="70FC15DFFC99D6AD" modified="2014-05-14" version="1">MVGSKRKKPILKSCILRLGDFGVSIIRRGMSWWGDSSFMPSPCFSPTAITTQPPRTVALIFNMAITIILGSQWGDEGKGKLTDILAPEAKLCARAAGGHNAGHSIVANGVSYSFHLLPSGLINPKCMNFIGSGVVFNVPQFFKELQDLSDKGLEAVHDRIRVSDRVHIDLQLHIAADGLEEQELGEGKIGTTGRGIGPSYSCKAARSGIRLADVFNPKLFEQKLRRLADGYRKRYGDLFKYDVEEELAQFEEYRHKLRKYSVDGVSFMKSAQKSNTPILIEGANALMLDLDYGSYPYVTSSNTSLAGIIGGLTLDPTKITEIIGVVKAYTTRVGSGAFKTEDTGEVGTKLQEIGREWGTSTGRRRRCGWLDLVVLKYSNDINNYTALNLTKLDVLDTFETIRVATAYKIDGKEIDSYPADLDILDQCEVVYKDFPGWQTPTTNAKSFEDLPKEARAYVEFIEEYVGVKVKYIGTGPDREAMIKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHK7</accession>
    <name>X0BHK7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14267</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979334">
        <property type="protein sequence ID" value="EXK81306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHK7"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF29">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="36"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK81306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="535" mass="60306" checksum="D186B56A8E6FC2A3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHW4</accession>
    <name>X0BHW4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_13894</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658423">
        <property type="protein sequence ID" value="EXK81725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHW4"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF201">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0274">FAD</keyword>
    <keyword evidence="3 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="9">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="10">
        <location>
            <begin position="279"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="535"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="580"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="534"/>
            <end position="535"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK81725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="617" mass="67252" checksum="BCB7F5F3FF70063A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BI14</accession>
    <name>X0BI14_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_17202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658545">
        <property type="protein sequence ID" value="EXK78114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BI14"/>
    <dbReference type="HOGENOM" id="CLU_036015_1_0_1"/>
    <dbReference type="OrthoDB" id="4367324at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="484" mass="55269" checksum="88424A2305AE996B" modified="2014-05-14" version="1">MPTILEVLTGRNVSINSDSVISGTNTTVRTNIQPDDWTPWRDFNYSTITHIFHAELQKPYRVEKGPKPLEKELIISDERTLETLFLKFLSPTVNYALNDQAGQAFLGEGTRCSDDADWSTISDQWFDDRGYLNLLPGDTKLDAKWRPSMLSDNFNEWQKVVSQVATYMARNCTRYGFILTDTKLVVLRLTRERIDAGMAMSRPQRTTATNFIHQRHSSDISMASTSISGSSYSDSDPENWAYCNPEYAVIDWNANGSRLTVKLALWALARMATSGDRHLDYSYPDLDTWRWADGYYVHNSSGVIKTKLSKHDVYQEAGTTSENTGMNIAGGSTQNESEQNNYPQSQYDEENAGETDQPGYHRGDLPIHMSGNPTFDYQRQDLPPQQDDEDADDDDNDDDDDNDDDDDNDDDARTEVGSSHQHREHSRRSRIAVTIRIHKKGGGLYYVNARGDKVDTKKRNWTKVRDGYELEGHSHRYYTKRFPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJ25</accession>
    <name>X0BJ25_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658420">
        <property type="protein sequence ID" value="EXK81851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJ25"/>
    <dbReference type="HOGENOM" id="CLU_1129088_0_0_1"/>
    <dbReference type="OrthoDB" id="5026901at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK81851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="283" mass="31485" checksum="480977F5E697C052" modified="2014-05-14" version="1">MSDFTPVFTRVLTFSYRNIDPLIHIRTLTTHYNFAAIMSNIHGVPPNGREAPETSCMVVGTGKSDSNEPSSAASTNEGESSAATQPVLTIRPATRIVTINHVGELRFIGILDPLDRAVGYYFDNPHEDFLVRNVMARSNLAVRAVIFQGERGAGNHVARKLPSLYPGQGVREFHFNLPFRVAGPATFRQLRLPLGFRRCFLGLKPKGTVVHKLTRDDECSLPEVRRYNRIWHAWKQENGALPERKCDVALMAWPAMAYCAGGMSLEFVQELEVDSLGGTDVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BL17</accession>
    <name>X0BL17_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BL17"/>
    <dbReference type="HOGENOM" id="CLU_069414_1_0_1"/>
    <dbReference type="OrthoDB" id="2942798at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052396">
        <property type="entry name" value="Meiotic_Drive_Suppr_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="23196" checksum="FF6A9F0ABFC05855" modified="2014-05-14" version="1">MRYSDGSPTKVHWGNNRILLRIISKATGSWLQSKFPEWFLPDKIVLKRQKENWEEEFGHEVITYNRLRPIQGITIPKLYGKIQYANTRALILSDIGGSSLSTPDGAVLDEQDIVPLLHQALSSLNDYGVCHDDTKLDNFHLVANEGKDKIIIVDLESTDFDQTKEELAYMAKNKTKSLLLQYQDHLKCLEHGVLLPRRPVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLX6</accession>
    <name>X0BLX6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658454">
        <property type="protein sequence ID" value="EXK79903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLX6"/>
    <dbReference type="HOGENOM" id="CLU_2210186_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="107" mass="12038" checksum="7417E44635099F68" modified="2014-05-14" version="1">MSEVRDVNAGKQGLDALERGEKPSGDEVRPDQKSEQQVDENLVTWDTPEDPKNPKNWTMKKKWTALICGMLLVSPNFKPCVIHHLSPSSRSLNCSTLQIPSIVMQHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMB5</accession>
    <name>X0BMB5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_15394</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979341">
        <property type="protein sequence ID" value="EXK80043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMB5"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_6_1"/>
    <dbReference type="OrthoDB" id="2585655at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF34">
        <property type="entry name" value="PROTEIN HOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="57"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK80043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="552" mass="60703" checksum="A8C909BBD3C8890B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPP9</accession>
    <name>X0BPP9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPP9"/>
    <dbReference type="HOGENOM" id="CLU_043982_0_0_1"/>
    <dbReference type="OrthoDB" id="4737775at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="36675" checksum="B66CD03DF0C1EEF2" modified="2014-05-14" version="1">MGTVEPQDELTRRRERGRRSQAAFRKRQAQSTHALADQNARLKQNIQRLLDAARGDERPEMLGIFRDLALAAELEVPARISPDEGQPSNIGSMSGETATSDASDPRILFSDVHLPSTPSQATQYRLECSMWLDPLHYLRVSLPPQDILPYLGAGAETFAGLLFWSVMEHYQTVCTQHNSKTVIQKGLKHSKATQDIKPSFIETMAKARVEYKQTGSISQAHAVAAEKDLGLVLCSLIETEYRSTGKDPDQWLSCNGIEKRLRKTLSDDALETLRKAALGEGNAVLHYLLEDVKCRLYDSCVCFGDGPRWNVDVVDQLFTPFIRRGMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQI1</accession>
    <name>X0BQI1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQI1"/>
    <dbReference type="eggNOG" id="KOG0371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023125_0_2_1"/>
    <dbReference type="OrthoDB" id="10267127at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006798">
        <property type="term" value="P:polyphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00144">
        <property type="entry name" value="MPP_PPP_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050126">
        <property type="entry name" value="Ap4A_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850:SF4">
        <property type="entry name" value="ZINC-DEPENDENT ENDOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="40"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="404" mass="44377" checksum="C6E577C9795D379D" modified="2014-05-14" version="1">MPSHENEYEINTHSSTAHSHAEFPWYPLQTRIQDVIAPGRLIIVGDVHGRLPELKKLLEKVAYSKPNGDKLILVGDLINKGPDSPGVVQLAMELGASAIRGNNEDRVLAAHSAIKKGDDTKLVERLKRLALEAEKENDKKDGQPAPSETKEDLKSISPEDLKPYSSESDFTTAANLSDEQISWLASQPLVLRIKLRKGATSPPWNSGTLLVAHGGLVPLLPLEEQDSWAVMNMRGLVYPDPEATVTEPIRAGLLKGAKSRTRRYAAYGDVNDADIKTELSKWADIINNGEGFSGQYKEGVIGFPLETREGDWWIDAWNRWQNSIRDPEKRSIVVYGHDARVGIQVGADSPEVARYTFGLDSGCVYGKSLTAMIIGEKEDGKGLSHSIVQVDAIKRDEGNEGEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRE1</accession>
    <name>X0BRE1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_11253</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRE1"/>
    <dbReference type="eggNOG" id="ENOG502QTP4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029718_0_0_1"/>
    <dbReference type="OrthoDB" id="5823761at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF5">
        <property type="entry name" value="CBM1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936623" description="cellulase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="8">
        <location>
            <begin position="57"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK84730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="346" mass="39203" checksum="BFE3FA484166D317" modified="2014-05-14" version="1">MQLKTFTFLFAAQTAIASQVKWAGVNLFGLANDVNILGSAYNTFLDLSCEPSYHSYPYINTVEDYKSWHDKGFNLFRIAMAWQHVQTSLGGSLNETNMEAVDKLVKVITDDGGQAILDIHNYARWYCAVIDQPEVSFLNPNITVTNDHFADLWTKLAERYKSNPKVIFQLMNEPHDLNITKWSATNQAAILAIRKVTEKQKILVSGTQFARLVDWEAFSQPGIGPGLIQDPANNTLYDFHQYFDDIAGAYGLCEPWSGYVKRFEAVTRILRRNGFQGTVTEFGGGPFPQCAETIQSMLAFLDRNSDVWYGWTAWGSFNESSDLYLSLDKNSTYNLITRTLEKFVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTL2</accession>
    <name>X0BTL2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_10592</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxB family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTL2"/>
    <dbReference type="eggNOG" id="ENOG502RZ5S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087059_0_0_1"/>
    <dbReference type="OrthoDB" id="5294024at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039020">
        <property type="entry name" value="PaxB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42038">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42038:SF2">
        <property type="entry name" value="TERPENE CYCLASE AUSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25129">
        <property type="entry name" value="Pyr4-TMTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK85520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="274" mass="30290" checksum="4B098691A8A129FD" modified="2014-05-14" version="1">MGSSDIPPPSAPPWLVPASTACLSLGITFWLIAYILMIRRSLATHATPAPLVALGLNLGWEVVYAFGVCEAPIETYGFMLWLLLDIVVLYATLKTAPRSFASSPLIANNVALLLFLVFVAGVVGNGLFVWWWLKEPHRGYGIKWGKNWKGLEARDTTELAYWSAGVAQMIFSVSALAMLLQRGHSGGQSYAIWFCRFVGTVMGLPVSCGLMWWYWPEAHGFVFHPLGIFITGTSVICDLAYPFLLAYVRTREKVLPDGSLVDGRLEAETEKKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BU44</accession>
    <name>X0BU44_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK82024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BU44"/>
    <dbReference type="eggNOG" id="ENOG502RKTB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148148_0_0_1"/>
    <dbReference type="OrthoDB" id="5094464at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="89" mass="9901" checksum="C171B243DB81F556" modified="2014-05-14" version="1">MSYQTKTVQVCDRCTGTSAGTYGPITSYGRGPLTQIDGNTEDSCYGVELNEEEVSIGMCQNCRILEAQEQEWEQANDSDDEEMEGAYIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUA8</accession>
    <name>X0BUA8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUA8"/>
    <dbReference type="eggNOG" id="ENOG502SIS9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_720724_0_0_1"/>
    <dbReference type="OrthoDB" id="3763773at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34714">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34714:SF2">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="392" mass="44082" checksum="672A9DC9CB3BD3FC" modified="2014-05-14" version="1">MIPAAAGKAVEAADKIAKIIETIKQVIEKIKELYKKLKPILEKLKKLAETIQALGYQNATALWHIFKEKVDQIEETVATIEFPAKEEYFFALRTLVINGKTYLQTQENLCQRGNELAIILLKVKLQHKEKQRLTLSAKATEQQGAVLDLLKRAMFDRLLSIRSLVFLDFYIYSEAYMFHALTDKPPVNISPVKPVLDYLEDAARFQGNFAAFGSRVMVQQRKFSILTCGDAVNTSSLRDRLLKDKSVFVSLDPKDAMFAGFSRIRVSKARCYLEGASVAPDSDATGESAGIRLFLKTSGRFYDINLPGRKDGAAPFNAFVGDALALLFEYSVEDRSIICDGEYGQNLDYTRQSPLTEWELSIGAGGLQARDLDFTNLKGIRMEFWCDITLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVH3</accession>
    <name>X0BVH3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_12751</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658408">
        <property type="protein sequence ID" value="EXK82918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVH3"/>
    <dbReference type="eggNOG" id="ENOG502S9N5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065416_2_1_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF1">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="51"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK82918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="285" mass="30601" checksum="5E88AD7AC5A4C0C9" modified="2014-05-14" version="1">MSSAPKLTATEHFNKTADKYEATTGGGTRELAQHAISFIADLRPLTSESKILDNACGTGIVTDIILKSGIQPEIHAVDVAENMVSIARDRFSSHPNVHAAAMAGEELSFPDNTFTHSVTNLGLMYFTDADKGAREISRTLHPDGVAVVTGWTTMGHIKIIQEVQAQIRPDDTPFKPPVPDIWLDPEHTKAVLSGAGLDVHTSTLIDVHLGGETADEVADLLTHGFGSRAFQSWSEEEKEKGAELMKKIVRERAVPFTRPSGSGVGIKVTGPIFVARKGSGRVLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVJ1</accession>
    <name>X0BVJ1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_09886</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BVJ1"/>
    <dbReference type="eggNOG" id="KOG0610">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_84_4_1"/>
    <dbReference type="OrthoDB" id="432483at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05574">
        <property type="entry name" value="STKc_phototropin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000121">
        <property type="entry name" value="Serine/threonine-protein kinase nrc-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000078">
        <property type="entry name" value="Serine/threonine-protein kinase nrc-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45637">
        <property type="entry name" value="FLIPPASE KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="244"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK86170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="619" mass="68039" checksum="237013381B5834EF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWC2</accession>
    <name>X0BWC2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Meiotically up-regulated gene 190 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_09893</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWC2"/>
    <dbReference type="eggNOG" id="KOG1012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002125_2_0_1"/>
    <dbReference type="OrthoDB" id="419768at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04041">
        <property type="entry name" value="C2A_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21676">
        <property type="entry name" value="SMP_Mug190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057349">
        <property type="entry name" value="C2_Mug190_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037767">
        <property type="entry name" value="C2A_Mug190-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348:SF3">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25331">
        <property type="entry name" value="C2_Mug190_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="373"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="245"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="470"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="659"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="696"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1053"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="33"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="703"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1081"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1119"/>
            <end position="1139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK86176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1201" mass="133610" checksum="825F30C47D4CE962" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BWT7</accession>
    <name>X0BWT7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_12665</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PC-esterase family. CASD1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658407">
        <property type="protein sequence ID" value="EXK82969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BWT7"/>
    <dbReference type="eggNOG" id="KOG1699">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1932925at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012419">
        <property type="entry name" value="Cas1_AcylTrans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057106">
        <property type="entry name" value="NXPE4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13533">
        <property type="entry name" value="N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13533:SF1">
        <property type="entry name" value="N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07779">
        <property type="entry name" value="Cas1_AcylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24536">
        <property type="entry name" value="NXPE4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="486"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="520"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="576"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="620"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="650"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="681"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="domain" description="NXPE C-terminal" evidence="10">
        <location>
            <begin position="67"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Cas1p 10 TM acyl transferase" evidence="9">
        <location>
            <begin position="330"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK82969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="848" mass="95431" checksum="9DF6E0FFA8555099" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX16</accession>
    <name>X0BX16_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_12179</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX16"/>
    <dbReference type="eggNOG" id="ENOG502S52J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018547_0_0_1"/>
    <dbReference type="OrthoDB" id="167809at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051473">
        <property type="entry name" value="P2Ox-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42784">
        <property type="entry name" value="PYRANOSE 2-OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42784:SF1">
        <property type="entry name" value="PYRANOSE 2-OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="252"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="7">
        <location>
            <begin position="473"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK83478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="540" mass="58673" checksum="AD3726C399408F73" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX24</accession>
    <name>X0BX24_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_09723</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX24"/>
    <dbReference type="HOGENOM" id="CLU_001265_4_4_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="54"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK86451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="487" mass="55840" checksum="A42C3A24BA8B2E68" modified="2014-05-14" version="1">MTTNKNQSDSEQSVIMTEPSPVQMSKPTRRWWHWHEPGASKEEKWLIFKLDAAILTYTCLTFFVKYLDQTNVTNAYVSGMKEDLDLYGNQLNWLTTYFNIGIIIVAPFSTIMLTFIKPRWWLPACTMAWSLLVLGMHKAETAETLYILRFFTGLCESGAMPGSFYLIGSWYRKSEISRRTTLFWFSSVSGQMLTGYIQAGLYRNMNGRLGLAAWRWLFILDFLISVPVVILGLIICPDEPKAKKIWWMSEEEKQRCIERMADEGRDAEGSHWDRALIKQVLRSWQLYAFCLAWGFMELTCGVNLQRWMTLWIKSLRVDEKPKYSTEKVNAIPTVVGCTGLVWMLLSAFIADSYQNRALPICILGCVQLFSYIVLLVWPSSEAFIMAAYYLASAYSALSPLISAWLNSSCGGKKQLRALTTGLMVSIGYAVETVAQQEMFPISQAPKFKQTHGYAFRIAWIVVMIVWCSVCLLLLERHFSARQMKPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX67</accession>
    <name>X0BX67_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_12617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX67"/>
    <dbReference type="SMR" id="X0BX67"/>
    <dbReference type="eggNOG" id="ENOG502QQ71">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027506_3_0_1"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02183">
        <property type="entry name" value="GH16_fungal_CRH1_transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF68">
        <property type="entry name" value="GLYCOSIDASE CRH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936774" description="GH16 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="18"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK83099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="274" mass="29311" checksum="6C2E3A40A31D3ABE" modified="2014-05-14" version="1">MFSKAIAALALAAPLVSAQTFTKCNPMTATCPADPAFGKDTVHCDFTKGACEAFAEDAGTALEHNEKGAVFTISGPNQAPTIATGKYIFFGRVDVEVQASTGVGICTSAVLQSDNLDEIDWEWLGGDNTQVQSNYFSKGDVSTYDRGEFHPVANPTGQFHLYSIEWTPSAINWMIDDVVVRTLPYTDATGPNGYPQTPMQIKLGTWTAGSPDAAPGTIAWAGGLADYSQGPFNAYYKSISIVDYAGTDAPTTSSVREYLFGDHSGSWKSIQQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX78</accession>
    <name>X0BX78_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_12629</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX78"/>
    <dbReference type="eggNOG" id="ENOG502S9I1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076139_1_1_1"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="154"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK83109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="225" mass="26293" checksum="4BE008D760B74FFA" modified="2014-05-14" version="1">MASKDAKLANLQDKEHFPVFEDLAWDNHLDPHYYRERENGFWEPRKHWVFIGEIFKVEIDLRVKLTVKDRDGLKIPVAIYTEARGVEIGPSNLQVGNTVVIFYAVKHLFMDMTIGIRHEDLQYLKIFPISLDNMMQLSDRVQTHPTLTDGMRTCHACSKKSAKLMKCAKCGFFWYCGQNCQLRGWNEKGHKADCKMLRDGNFKGLFSIKWGEFHNHISFPLRISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BXG5</accession>
    <name>X0BXG5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658405">
        <property type="protein sequence ID" value="EXK83164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BXG5"/>
    <dbReference type="eggNOG" id="ENOG502RAFQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067634_0_0_1"/>
    <dbReference type="OrthoDB" id="5290015at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="358" mass="40439" checksum="673F08CD4B067552" modified="2014-05-14" version="1">MSFRGPRSRPRQEEGGGLNNFRVLDQSQPDPVNTPDLPQSSRTFRVAAFVFHLGMSMLESRRGREALVMLISDAWRASDRRAQKTFIPKSNFQTDLNEARRFVDTFLAKCRAEPPNIIISDRITGEGLAQRVDWPSILGSQIGDYNPKWAAMFRLNKTVVDSAVNAAELRDVEALQKILFLLSISVAHELVHMLMGFMFGDSERLTPPVINHPPGTPRGPRAGESGRYWEAKFFGCVVEAHHDPRDPRGSNQAGIFFGTLDGRRSFPMQHQTIMRYVHLDFTVPIYSSNIATSRISAGAVAMQDIRRPSRFPDVGGDLTPYFEMINSLPRQRVSRDGLEEIMHMAMRPEFVRPVSVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1A9</accession>
    <name>X0C1A9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1A9"/>
    <dbReference type="HOGENOM" id="CLU_2469129_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="88" mass="9671" checksum="D267A6348E5FB3A3" modified="2014-05-14" version="1">MDLRPGLILLSRTSSEEADPTICWFSQGPKVLVRLPLFEHGVYQLCGAVTSSSEFNMEKPVFEIHRCLAPRAQCSSVDIASMGRSSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C227</accession>
    <name>X0C227_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_11070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C227"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011025_0_0_1"/>
    <dbReference type="OrthoDB" id="413885at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF4">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936897" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="481"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="772"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="776"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK84829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="793" mass="83960" checksum="F7CAA28069BBA120" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3D1</accession>
    <name>X0C3D1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_10665</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3D1"/>
    <dbReference type="eggNOG" id="KOG3991">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014832_6_1_1"/>
    <dbReference type="OrthoDB" id="18915at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22749">
        <property type="entry name" value="Otubain_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.60">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.20">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019400">
        <property type="entry name" value="Peptidase_C65_otubain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042468">
        <property type="entry name" value="Peptidase_C65_otubain_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042467">
        <property type="entry name" value="Peptidase_C65_otubain_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931:SF15">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTUBAIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931">
        <property type="entry name" value="UBIQUITIN THIOLESTERASE PROTEIN OTUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10275">
        <property type="entry name" value="Peptidase_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="8">
        <location>
            <begin position="203"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="30"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="462"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="598"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="46"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="490"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="518"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="598"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="614"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK85299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="624" mass="68302" checksum="537904B01384D66D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0C598</accession>
    <name>X0C598_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_10037</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK85979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C598"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_0_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF230">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="58"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK85979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="462" mass="49156" checksum="89638E66187159A4" modified="2014-05-14" version="1">MVTQQKADSQGREKNPDVDVESTLPYVTISLQDEIEDSNSSSSELSKPIVKDNESDWGAWICVLGSLLFLITSAGFNASIGIVQSYFSLHQLKDNSVSEIGWIPGIYLFLSMAPSFLYGSLLDRYGPRVLSAVGGICSAATFVLMAECKTYWQFMLCLGAFGSIGTGIKSTVAVGVVGKLFVRRRGLAIGTAVMGSSLGAIIFPLVLRSTFENLGWAWSMRIVAIVVSCLTIVGFVCFLPFKRLAVFSSNKQDKVEKSGPAFYLSAWKNPSFASVSCGICLMEFVNCGIGSLLPAISTGAGFTAQDGYTLFAIMGGCSCISRLVMGLLSDRLGGISSMVGTLVLIVILMSAVLIPFSTTSAPLLYVFSALWGLMAGSFYALSPVIVGNTCEPKDYARYYGSTNVGVGLSLLIANPVSGIMLEKVGAKPLAFFYLGIVVLAGLSITVARGLLLSSFTTLRARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5G4</accession>
    <name>X0C5G4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiaminase-2/PQQC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5G4"/>
    <dbReference type="HOGENOM" id="CLU_1004874_0_0_1"/>
    <dbReference type="OrthoDB" id="2851859at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19359">
        <property type="entry name" value="TenA_C_Bt3146-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939119" description="Thiaminase-2/PQQC domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Thiaminase-2/PQQC" evidence="2">
        <location>
            <begin position="82"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="281" mass="31576" checksum="22A083F8AD4A6ACA" modified="2014-05-14" version="1">MSLSWTRMFLVLPALAISAAALPHERREVPATAEPIITPAECPHHNPEVQDGTLVAQLWRQNCDLVTKFLNNAFTAAQAAQTSKGTLESLQYYFIQDYYYLTLTVPHKAYLLKSLDPDESAADQTSAINETVLDMTSDLEYASHFRQDLTSPDHLNVSSTVVKNAKLEPVLRQYVDWLGENTKLGWYLFSVSRVPCIYGWAEIAYQLNQSSSTVRGTKFFDEWISPNLDWSYGAKLSVELQEVLSANNNTETFAVANGLFRQALEFETAFFESAVGKVLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7G9</accession>
    <name>X0C7G9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658384">
        <property type="protein sequence ID" value="EXK86744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7G9"/>
    <dbReference type="eggNOG" id="ENOG502SPSM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_606968_0_0_1"/>
    <dbReference type="OrthoDB" id="5213630at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK86744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="478" mass="54637" checksum="35FE224C31E01BCF" modified="2014-05-14" version="1">MEAQGPSQKPGFPLNLETEVSGPPNAIMDQGNPLTKLEEDYNDLLGRIPKFPAFSDLPIGSEFQDKPQNHPVPMQSNTTPEDWTLGEIFGAQQENYTVFLDNYRVVSSEERSNLAQVVQTEVQNGMDRVFNYVKSFIPQPAQASTTSTTTELRAQLKKEKNYVQKLSGDYNNLLQHSHKQKQDLEKVNARLDDVLRERDQLRQLLEGGSLANSDKATDDSIRGKWKELAYNIRCLARHLAHNPPRQQLDDIARERLRFIAGDYYTLLEDEDYRELIIMSYLWVTVQDDVFDARQTIWGGPELKSFKAVRDRIISRVGDGINIPNCDDPIAHAARWLAQGSVMMCNLWERDDRGIRRLVLAEAKRLRPFHSTHQSTADRCDRKVVDQLREILGSAIELDQMMMRSKAIFQIHWRDESQSLSTAEMWNEDVMDSEASTKILSPKSRVIFFISPIVYKAGTADGQRYNSRMVLAKASVVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7M2</accession>
    <name>X0C7M2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7M2"/>
    <dbReference type="eggNOG" id="ENOG502SPBG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060131_5_0_1"/>
    <dbReference type="OrthoDB" id="61113at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="87"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="226" mass="26414" checksum="8E4579AC7690AEE9" modified="2014-05-14" version="1">MSGYQLQSPCRVEDGLLIAQSQVSAFFEEAWWRLSWTNRTRESLIQSIADRSPKNLLTNREIRRHQNIVHLQTGDIVGYARWILPESHKDAWLEAQTPDVSDEQREVFAKRHAETDWNPREDNDKLDDHIDGWREKHKQGRDMELHYLCVHPDHQQKGLASLLVNSGLEEAKKLGLDVIIVAMGRRALGLYLKHGFELLEEKSQSMSYFGVDELYETFYLRKKAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0C871</accession>
    <name>X0C871_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C871"/>
    <dbReference type="eggNOG" id="KOG3695">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004692_0_0_1"/>
    <dbReference type="OrthoDB" id="5350595at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019384">
        <property type="entry name" value="FHIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705:SF11">
        <property type="entry name" value="FHIP FAMILY PROTEIN CG3558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705">
        <property type="entry name" value="RAI16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10257">
        <property type="entry name" value="RAI16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="630"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="724"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="770"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="872"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="639"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="789"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="920"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="948"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="966"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1019"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1074" mass="120506" checksum="6AC86DABE0EF31B3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0C966</accession>
    <name>X0C966_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08654</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C966"/>
    <dbReference type="eggNOG" id="ENOG502QSJS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016583_1_1_1"/>
    <dbReference type="OrthoDB" id="3918848at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018829">
        <property type="entry name" value="DUF2433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052743">
        <property type="entry name" value="Glutaminase_GtaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056812">
        <property type="entry name" value="RRM_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987:SF11">
        <property type="entry name" value="DUF2433 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987">
        <property type="entry name" value="GLUTAMINASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10360">
        <property type="entry name" value="DUF2433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25061">
        <property type="entry name" value="RRM_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2433" evidence="2">
        <location>
            <begin position="280"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding" evidence="3">
        <location>
            <begin position="516"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="665"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK87748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="678" mass="71709" checksum="6BFD86C5B532B702" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9F0</accession>
    <name>X0C9F0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979348">
        <property type="protein sequence ID" value="EXK79307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9F0"/>
    <dbReference type="eggNOG" id="ENOG502REH0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038297_1_0_1"/>
    <dbReference type="OrthoDB" id="9978720at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12809">
        <property type="entry name" value="Esterase_713_like-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF4">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="109"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="412" mass="45366" checksum="D4FEAAF79C411DE9" modified="2014-05-14" version="1">MMQYICDCSFRSFLFCSPASALHLLPHPSIFSSHLPTMRFTSLLVAATATFSQCLAASYGSQGEVPAIRTYFMVGGGYVDDGAGGEIFRDQMYVERLVPTKGPYKSTPLVFIHGQAQTGTNFLNKPDGGRGWASQFINQGYEVYIVDQTFRGRSAWAPLAGATKPSTYSAEIIEQRFTAVQEFNLWPQAEKHTQWPGTGKRGDPVFDAFYASNVQFINNATYQQETVQAAGAALLDKIGKPVILLGHSQGGMMPILVADARPKLTKGLILLEPSGPPFRDAVFSTKASRAYGLTDIPLVYSPAVTDPSTDLVQEVQPSRGEDFVECILQAKEPAPRRLVNLAKKPILLLTSEASYHMPYDYCIARYLKQAGCSKTKHIELGEVGIHGNGHMMFMEKNSDQIQALVERWVRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0C9T3</accession>
    <name>X0C9T3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Chitin synthase</fullName>
            <ecNumber evidence="2 10">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_15922</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cell membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 10"/>
    <dbReference type="EMBL" id="JH658470">
        <property type="protein sequence ID" value="EXK79452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C9T3"/>
    <dbReference type="HOGENOM" id="CLU_045174_0_0_1"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK79452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="403" mass="45755" checksum="4CBA6D727956B7D5" modified="2014-05-14" version="1">MRPRHTEILVGITVYNEPKHLLRRTLQSIVQNLWYLNIRTQSRVWGKGSWYKIVVCILIDGIESVDPGVLDVLTSIGLYQNGLCKKTTEQGEEVTGHLFEFTSHLATHLDCEDYLDGNGNSYKPESRSMKFPVQLMLLMKTSNCGKLNSYRWLYNGFARVLDPNMTVNLDVGTKLGKQELFKLLKEFDLEPMLAAACGEISCSLGGSWLNLLNPSVTAQNFEYKVGFQLDRTFESATGFLSLLPATCSAYRYVGSSGKPLEDMLLGDPTWIQGHNRDRPALSPVNLNRHLPDDRVICFRTISKPNTQWLLKYVPVTATTIIPMTTTDFINQRRRWLNGAFFSTIYVLKRCGHLWRSDHTIKRKVAFFIPLLHSVLALVLAWFSLAVFLLSTFTINSMLGDPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAE8</accession>
    <name>X0CAE8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Sexual differentiation process protein isp4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_08713</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658381">
        <property type="protein sequence ID" value="EXK87819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAE8"/>
    <dbReference type="eggNOG" id="KOG2262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="541"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="651"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="685"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="717"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="762"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="796"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK87819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="862" mass="97102" checksum="C352F8FF59388129" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAZ6</accession>
    <name>X0CAZ6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAZ6"/>
    <dbReference type="eggNOG" id="ENOG502SUQ0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108553_1_0_1"/>
    <dbReference type="OrthoDB" id="3520229at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="182" mass="18383" checksum="5A8398CFB6DB004E" modified="2014-05-14" version="1">MSSTTLSTASAVPTACTNLYDTPNQDNTCAMPFKDNHTEIMQKCCGDAKIVSYYNGCGLYCVALDQTIGELAKCLFSNGAPDADVFCSGSKKTTKTKDADVPATAQASVISGDDNKDDGDKSSTGTASGTSTSTGTSSSSSETSTESGNAAAGFAPKSSINTLGLAIGALLFSSMAAGAFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCF3</accession>
    <name>X0CCF3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_15120</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4"/>
    <dbReference type="EMBL" id="JH658447">
        <property type="protein sequence ID" value="EXK80337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCF3"/>
    <dbReference type="HOGENOM" id="CLU_049944_5_3_1"/>
    <dbReference type="OrthoDB" id="3558741at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF61">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK80337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="224" mass="24457" checksum="16EEEA8D972026A3" modified="2014-05-14" version="1">MATNVPMKYDMLRRLRVADYITLSNGFCGVLAIFCAIQKSLLPAHLLIFLGYEFDRFDGIVARARNECSEMGKQLDSFCDLVSFCVAPAVMIYCAGFDTVVDQLALALFVCSGVARLSRFNIAAHLVPKSDQGKAMYHEGLPTAYAALLISTAVAVAEWTGCLTNLASGSHYPVIIVVLIFSAAMVSKRLHLYIDGAYSIPAVSMLVFAGCWSHSPMPIRTVLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCM7</accession>
    <name>X0CCM7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Xylan 1,4-beta-xylosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_08211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCM7"/>
    <dbReference type="eggNOG" id="ENOG502SM8A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016508_2_1_1"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09000">
        <property type="entry name" value="GH43_SXA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF12">
        <property type="entry name" value="BETA-XYLOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="7">
        <location>
            <begin position="326"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="5">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK88973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="532" mass="60377" checksum="0811CD8DF8887183" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCU2</accession>
    <name>X0CCU2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCU2"/>
    <dbReference type="eggNOG" id="ENOG502RMVE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_842106_0_0_1"/>
    <dbReference type="OrthoDB" id="3561723at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="362" mass="40058" checksum="E5F9524C9B40C237" modified="2014-05-14" version="1">MFSNTVQHTLALRQELRSHLHTIRASIGLGIMAELPEDSKSPIPSSVFDSDADDTNFMSPVLLPLTVSIDDDDAGQLSAPQTNTPAELSEPRQIISSGDSSELLQAELRRPVLAGTYFNEPAYLVQLRLHLSLSSGNRSWLSRIQTVDIHVLVEDAPRDDGQNVSDDSEDSDDDYEEEEFPHPAIVKAFPGPSGWEGSPQSAEVTITNGIGLQVGYNPASISYNIGESRTRTKTGAIKVKVAHKGPGQNKLHVRVEESSVDKAGVPDYLLVPFIIRHRSRRFRMRVGIHARFGFWRGKLAEVVPILGRADEPLFFDPRVMRRAMEKGRRGVNGERVVEWRGALDEVALQEYSSLVDENATQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CD99</accession>
    <name>X0CD99_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6594 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CD99"/>
    <dbReference type="HOGENOM" id="CLU_051118_3_2_1"/>
    <dbReference type="OrthoDB" id="3533814at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046529">
        <property type="entry name" value="DUF6594"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502:SF3">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20237">
        <property type="entry name" value="DUF6594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6594" evidence="3">
        <location>
            <begin position="63"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="314" mass="35209" checksum="201912B70FD1A4CB" modified="2014-05-14" version="1">MTNDIERGSSETTIKPTFVRSVLTWASSWRVPGAFSLKSQNEQASGVSSDTERITVEDRRKGYPRFSALMAGHSSFQIYRRFSDLRTRLLLLTQDEIVELEEQLNQIDQAEKSALFLASRREDRNSDRSVITTKLRSALSAYDELLEGSQRSLKYESPHEKYVSSLQRWLSGNSCIARSETKFLKNSDDLLSLCPGEDGIVAWLERNVCDKVVRRFSRSSENISNDPHVQIFSRSSTMRVARAILSPLIVFLLLAPVVICNMIDSQPARLAIMIISTAAFVCCMSLLTNAKTVELAVAGATYTTVMIVFVSNTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDN0</accession>
    <name>X0CDN0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 14">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="3 14">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FOQG_06157</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 14"/>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDN0"/>
    <dbReference type="eggNOG" id="KOG0480">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000995_3_1_1"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.870:FF:000002">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1640.10:FF:000009">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000115">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 14" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="16">
        <location>
            <begin position="480"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="818"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXK92286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="957" mass="105152" checksum="A56BDD6CC3D007E0" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDV7</accession>
    <name>X0CDV7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658436">
        <property type="protein sequence ID" value="EXK80807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDV7"/>
    <dbReference type="eggNOG" id="KOG4169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2158541_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="111" mass="12067" checksum="580BBD01377C8035" modified="2014-05-14" version="1">MSYSVKDRFAIVTGSSSGIGHALVRLLLNAGCWVAVADVRLRRESEATINEFSHSPSKGKPSAIFVQTDMFDWAQISALGKTTLGRFGRIAIVVNRARVHEPPSARLGQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEB6</accession>
    <name>X0CEB6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_05770</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEB6"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_2_1"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="29"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK92735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="377" mass="41984" checksum="C0EF0391DDC96A45" modified="2014-05-14" version="1">MALPFAPPPKSPLGRYRLLSPTASVWVSPICLGTMNFGNSWKEWMGECDQSTSESILDFFYEQGGNFIDSANNYQFQETEKWVGEWMRKRGNRDEIVVATKYTTNFRAGPGAPNIMVNFTGNGTKSLRASVEASLKNLQTDYIDLLYVHWYDGNTSIPELMQSLNQLVLSGKVLHLGVSDTPAWIVSKANEYARCNGLRQFSVYQGRWSAASRDFERDIIPMCQAEGMGIAPWGSLGGGKFKTEEQRNAREGRRVEASEKEIRTSKVLESIANRKNTLITSIALAYVMHKTSYVFPIIGGRKVDHLKANIQALTLHLSPEDIQEIDGANEFDAGFPNDFLYRGGNSIGGPDVWLLQMGGTFDHIQPPKPISPAARGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFL3</accession>
    <name>X0CFL3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK92991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CFL3"/>
    <dbReference type="HOGENOM" id="CLU_060140_1_0_1"/>
    <dbReference type="OrthoDB" id="4582561at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="364" mass="40448" checksum="8D333C8B5E509D11" modified="2014-05-14" version="1">MSSPSINCSQWTELNDFSEYIQDLDSETHFNEGILESCKSEICNAIYGTGNTDISGIGRSGKNSQRHEVAKAGLEAFVDSAAYFALALQLATIAVLARKDYGISTADLGAIEARISQSVAVISMMPLLYPIALLEPIAKNSTRANIKHNARLLLLSVTVALSFYPFLSRCIHAFDISPIGEGKGSEVSSTDWSVVEDMCFPAEYRNIGRSTTFKSLNGLELTASLITYIFTFWLLAGLPGTCYDHDEEAKDAKEAEDKTSWRERVNEWFGERPLVVVLPLLVFVGLTIPLLWVIFTLKNVQEQMSENMGEKYDGNYWGFGQIVSIVLFIPVGVEMAYRWRFGASYVYETDQQAKSSESHSRGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGB0</accession>
    <name>X0CGB0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGB0"/>
    <dbReference type="eggNOG" id="ENOG502S6JE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033726_0_2_1"/>
    <dbReference type="OrthoDB" id="2245989at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF1">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30900" checksum="567ADEC12395B0F5" modified="2014-05-14" version="1">MAELTQPPAPKRLGQLPQLTELKDPDDDWTGITEARDRRRRQNRLNQRAYRKRKARNEEYANVTPEEVHTNGLLIFTTARERAVAYAFMQLVHMQHSLKNHRPALLPSLIRLNAVNAVSSNAVHIGIPLQGLCCDDVISPWNALGPSSADGTLVTSSCPESLRPTRLQIEIEHHPWVDLLPFPQLRDNMLKGYTSGVFDEDELCIDILGLISSQGLDDAYLIVWGEAHDGSSWEVSVGFLRKWGWLLKGCPELVESTNRWRQQRGEAKLNIQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGS0</accession>
    <name>X0CGS0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone acetyltransferase ESA1</fullName>
            <ecNumber evidence="4">2.3.1.48</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="23">Histone acetyltransferase esa1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15 24">protein 2-hydroxyisobutyryltransferase ESA1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 25">protein acetyltransferase ESA1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16 26">protein crotonyltransferase ESA1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="30" type="ORF">FOQG_07233</name>
    </gene>
    <organism evidence="30 31">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="30 31" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="30 31">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac. The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination. Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins. In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>(2E)-butenoyl-CoA + L-lysyl-[protein] = N(6)-(2E)-butenoyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53908"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:137954"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:53909"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>2-hydroxyisobutanoyl-CoA + L-lysyl-[protein] = N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:15921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:131780"/>
            <dbReference type="ChEBI" id="CHEBI:144968"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:24181"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21992"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:21993"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:45949"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="4"/>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGS0"/>
    <dbReference type="eggNOG" id="KOG2747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011815_2_0_1"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106226">
        <property type="term" value="F:peptide 2-hydroxyisobutyryltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140064">
        <property type="term" value="F:peptide crotonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000022">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.60:FF:000001">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000002">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025995">
        <property type="entry name" value="Tudor-knot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF218">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE ESA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11717">
        <property type="entry name" value="Tudor-knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="11" id="KW-0010">Activator</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="31" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 30" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="29">
        <location>
            <begin position="212"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="28">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="28">
        <location>
            <begin position="87"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="28">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="28">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="28">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="28">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="27">
        <location>
            <position position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00031553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00074445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00075313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00076782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00077673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="PIRSR" id="PIRSR602717-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="EMBL" id="EXK90448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="498" mass="57408" checksum="24024818C8DA3F16" modified="2014-05-14" version="1">MAGGTPSGEPTVGSGEPRLKSLATPETITTGCIAWVEKEGQPRRAEILSIKTTKSGKQFYCNFDNFNKRLDEWVPVIRLDFTREVEWPNPEKDKPKDPKTKKAPAAQSKKTQPSKKSQKRPGKREQSVASEANTPHPWTESQNRQKSASIGPDGESQARASVDGATPAAGDDMNVDEKEAEVKREPAEFSREVEIEKLRTSGSMTQNPTEVSRIRNISKVQFGRFDLYPWYFSPYPEIFSQEDVIFICEFCLSYYGDEKAFTRHRRKCTLQHPPGNELYRNEDISFFEIDGRRQRTWCRNLCLLSKMFLDHKTLYYDVDPFLFYVMTTRTEKGCHLVGYFSKEKESADGYNVACILTMPQYQRKGYGRLLIQFSYELSRIEGKLGSPEKPLSDLGLLSYRQYWSENILELLMGYNEREEKVTIEAISAALAMTTQDVEHTLQALRMQVYHKSDHKIVIPEKLIQQREKTKLKRKRTVDPTKIQWKPPVFTASSRTWGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CI11</accession>
    <name>X0CI11_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Golgi apyrase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_07253</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CI11"/>
    <dbReference type="eggNOG" id="KOG1386">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010246_3_0_1"/>
    <dbReference type="OrthoDB" id="6372431at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004382">
        <property type="term" value="F:GDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045134">
        <property type="term" value="F:UDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046036">
        <property type="term" value="P:CTP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006256">
        <property type="term" value="P:UDP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24039">
        <property type="entry name" value="ASKHA_NBD_YND1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF121">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATASE MIG-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01238">
        <property type="entry name" value="GDA1_CD39_NTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="509"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="538"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="580"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="181"/>
            <end position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK90474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="73642" checksum="CF0706EF8F92E33D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIU7</accession>
    <name>X0CIU7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_13218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658413">
        <property type="protein sequence ID" value="EXK82507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIU7"/>
    <dbReference type="HOGENOM" id="CLU_3320066_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK82507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="39" mass="4429" checksum="13B6A9AF1A7DE164" modified="2014-05-14" version="1">MPVDLFDPSRILPLSSSKWLKIVVFTVGCKKYSQVCKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJI1</accession>
    <name>X0CJI1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK90999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJI1"/>
    <dbReference type="HOGENOM" id="CLU_3399491_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="31" mass="3821" checksum="E5B428876587B5FE" modified="2014-05-14" version="1">MLMQKLKHSFSLKKRQRWPKQICMLAKKHVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJL8</accession>
    <name>X0CJL8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJL8"/>
    <dbReference type="eggNOG" id="ENOG502T645">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083067_0_0_1"/>
    <dbReference type="OrthoDB" id="5097987at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="292" mass="33146" checksum="03D97C9C57145A87" modified="2014-05-14" version="1">MEDVGSRTVVAAATAAEDPPIPPSTYNHTTIPNNTSSSDQSREPSLSSRPSLPWTPYSDSSIWIDKDSTDDHHSRFSHVHTPESSYGTRPPSVNEEAMRYHRRRQGKYKIPEERFNPDDRYRRSHRGRRGRHAHSSHRQPQRNERRNSANTGCLRYAKHAETPADIVLEPQPDKTKVVGDKLTKKNENNGTTWRRISQGLGLGKSKKNEKPEEHPPVKAEDVPRRKSKWKFWAKQPPGDDAEASDAPETSDPNNEPQFTVTSDSRPSLLESLEEAPISIQLHTVMRRLSQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKQ9</accession>
    <name>X0CKQ9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658406">
        <property type="protein sequence ID" value="EXK83132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKQ9"/>
    <dbReference type="eggNOG" id="ENOG502RXCX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028693_0_0_1"/>
    <dbReference type="OrthoDB" id="10033702at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937253" evidence="1">
        <location>
            <begin position="21"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="475" mass="51379" checksum="06CB1DCCED6C4368" modified="2014-05-14" version="1">MPSLISITALLGALASQVSASPANIAKRGLSLPPLIPKIPGVTEPLADNAPPLPILQLPTPPLDSPPFKVSNIKPKKIGYFWTGAGDNKHADFLVTASLDDDTFGEIIDITDVNTSGNSPHHLGTSLDGKTLVGGGLLSLLKTQDTAFYFDTSDPYHPKFDHSNRGILGSIVDEIRAKPDGGFFITYMGSAVGTSPGRLIETDANGNIIHEWPEDVEGTLNILGEQFSPHGLSVDFDKNIILTSDFVVPITILKPTLGIKKADTLRLWDLKSRKIISTITIPNGQGIQDVKFIPGNKESAALATAVGPGQVWIIYPFRKDSKGNQGVAKLLYDLGDKAKDSLAIYSDITDDGKFAYFTITLGNHIAALDISDLDNVKRLDDPDEEQPIIGPHYVKISPDKKNLLVTGYFVQGGAISIVNTPADYKGHWIDINDDGSLSFNRTIDFEKIFTKTRGGARPHSAVIFDLTDPKNPIYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLU2</accession>
    <name>X0CLU2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLU2"/>
    <dbReference type="OrthoDB" id="3205825at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="44118" checksum="DCF302DC2C1EC20E" modified="2014-05-14" version="1">MATEHGFLVPPNFKEEPPSDDDMNFASIIWGLSLGVTIFNCGKAMRQTQAAIRRRNRLTLYIMFIWLEVCSSTVLGIMVWLYLRGIIKPSFQYYFFIIVFWSIQVQCLIQIIINRVSLLMVVRRNGTVLKWTCFGILLAINISVFCVWIPARLQISEKYIHVNEIWDRMEKVLFAIMDAALNFYFIWVVKQRLVANGLQKYTRLYHMNMFLVAISIALDVSYGLSNSVCHIALTLFKILLIGMMSLPNSFVYVQFHPLVYLCKLHIEMNMADLIGKVVRAGNNQADGTHDYSSRSRTTVKTGTRPAGASRFGGGLTRTHIELGEEDEIELKHRENLEGIKKTVTTEVIRSPNSEDDEIMEHHERAVSEASSTNARHEPYSIEHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CMV4</accession>
    <name>X0CMV4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CMV4"/>
    <dbReference type="eggNOG" id="ENOG502S5R9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060985_0_0_1"/>
    <dbReference type="OrthoDB" id="4161589at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="38978" checksum="256F0A0D238A5714" modified="2014-05-14" version="1">MSASPPSGSSKRRVRTEAQMSQKRLADRVKHRENRQEHKQRMERMEADIAQIRKNLDTVSAQLRTLPQLSADLVALQQRSSQKPPGEAYEMDTSVETPDFPAGRRAPAAAPCAADHHDIPPAEVPEVVSSLFPTPSHVDCRCGVQHHSQADCLEYRSFAILYETHAAFPKDPLHARSLPRNPELPNMTLHSYGDNAVTCFLTSFLKGFEMASVETLFGVYFFAYRLMRWRLHPDPMTLKDVPPWLLPTEVQNTYPHPVSIDYIPWPDLRDFLCTNPRIKSRHSVKIYLESLQLKWPPGCPLMAVEGGQVCVSPEFEAIACDLNNWELGPPWLEAFPRLVSLVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQ08</accession>
    <name>X0CQ08_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03544</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQ08"/>
    <dbReference type="eggNOG" id="ENOG502R88V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031555_0_1_1"/>
    <dbReference type="OrthoDB" id="5326346at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="37833" checksum="86F6DC3A8F262E00" modified="2014-05-14" version="1">MKSISYDIDPGGDVELILKKPNKQNIVPESPTFHGNPVDPEFPNPPCLGRYQVFSELYPDGENENPDVEVRMRVSSRHLTFASRTFRAMLEGPWKEGNSSSRPIRQISAENWDAFALAIVLDSIHGRHHEIPTQITDGLLTRIATIVDYYECRQAMHFNYEVWAHGKTLPSKLRNAALLWLHVSWVFHDENRFRIAARLFVRFSIGAYDFETHDLPVSGVLDLLDGIRRTLINTFSEALDSLEQHMIDEDGCDYFKDPDCTAIVLGILVRERHMITKLDPPLVAPFDGAAYTRYYVGSAASVPQCRRTMILTNPMRKMTTRRNTPVPFKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQE4</accession>
    <name>X0CQE4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQE4"/>
    <dbReference type="eggNOG" id="KOG1018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025810_5_1_1"/>
    <dbReference type="OrthoDB" id="408702at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF179">
        <property type="entry name" value="TRNA(ADENINE(34)) DEAMINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="202" mass="21677" checksum="F03B672C7AAE406E" modified="2014-05-14" version="1" fragment="single">MDLSSLTPSTSLLTSQLTTSTYNNTGTAKMISDQDLEHLRLAVSLAHEALKAGDAPFGSVLVSSDNKVLQTDRNRTVTGSNGDGRADSTLHPEFTLARWAQLNLSDEERAKSTVYTSGEHCAMCSAAHAWCGLGRIVYVSSTEQLEAWKAEFGVGAPVAPLSINQVAPGITVEGPVEELAKEVYQFQVENWTAKGFKSKSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU23</accession>
    <name>X0CU23_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK85992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU23"/>
    <dbReference type="eggNOG" id="ENOG502R9ZE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1517996_0_0_1"/>
    <dbReference type="OrthoDB" id="3598746at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939604" evidence="1">
        <location>
            <begin position="18"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="149" mass="16426" checksum="F7E849E625DC6018" modified="2014-05-14" version="1">MKFLPLAVALFATLTVAAPSSPSDIQARSCVCKKVGDDWICTGTKCYDKVKRDLVPRQCSCHKIGDEWLCGGPKCPRDLPEENKLAKRQCSCHKVGDEWLCGGPKCPRSLPAEESGLEKRQCSCKKVAGEWICSGRKCPRDLSHLMGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV94</accession>
    <name>X0CV94_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV94"/>
    <dbReference type="HOGENOM" id="CLU_2026823_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="122" mass="13356" checksum="C2DB7B9F95A15AA2" modified="2014-05-14" version="1">MPLIPTTTILSVAACLVRPPLPQKIHSAPNLRDADNSSSAVIVTRRSASDSIEDPTPPTPPIELQFLDSRSKNLSPLPSNPSRPTLSSTNSSSSTSGSYFTAHKLSRRQRNKLSEEIWKGYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CWZ3</accession>
    <name>X0CWZ3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CWZ3"/>
    <dbReference type="eggNOG" id="ENOG502T4SA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1365903_0_0_1"/>
    <dbReference type="OrthoDB" id="4160064at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="219" mass="23970" checksum="E142B0130EE920DB" modified="2014-05-14" version="1">MPPHSNSPLLPISTPTAIASPYEQPPPPAPTAANHVQRFAITTFSLARFARGVSLIAYPRFGLWALDIAPDGSAYMLASLIGIRDILLSGLLYTSDTTNAVTDSAARREVTRALATNLFSDALDAFVLIFYAAWSDDWGNPIAVIVISAVMAIFEHLTLWSLSEDDWAAHEYGSLGDDKKARMNAWLRELERCGPETYRPEQSVPPSSRASFRQYGAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CX70</accession>
    <name>X0CX70_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_01540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CX70"/>
    <dbReference type="eggNOG" id="KOG3166">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29563at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001921">
        <property type="entry name" value="Ribosomal_eL8_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00882">
        <property type="entry name" value="RIBOSOMALL7A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="6">
        <location>
            <begin position="120"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK98741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="261" mass="29246" checksum="F12D8B38DAE80CE0" modified="2014-05-14" version="1">MPPKSGKKVAPAPFPQGKAGKKAAKNPLLEKRPRNFGIGQDIQPKRNVSRMVKWPEYVRLQRQKKILQMRLKVPPALAQFQHVLDRNTAAQAFKLLNKYRPETKAEKKERLLQEATAVKEGKKKEDVSKKPYTVKYGLNHVVGLIENKKASLVLIPNDVEPIELVVFLPSLCKKMGIPYAIVKGKARLGTVVHKKTAAVLAVTEVRSEDKNELSKLISAVKDGYLEKHDQARRQWGGGIMGPKAQMKIIKKQKALEAATKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXU3</accession>
    <name>X0CXU3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXU3"/>
    <dbReference type="HOGENOM" id="CLU_036212_0_0_1"/>
    <dbReference type="OrthoDB" id="4738706at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="55410" checksum="C8B71911ACE85799" modified="2014-05-14" version="1">MNVGQGDASNLKAFVRHSNETSHGNRATARAAKDRELANDTIPAPYVLNMQPEGRKSQQSYEISGTADEAKGARGHHEQVLDPQKDAYQARSSSSKGKYSEDIGNVEPNPALLPKGKGQEQPSKEGYQKDLALSGDKVTDKPSNSKRRADDTKAPHKRSRTSMTTDTNKRPETFACPYYRKDPERHLDCINLKMIRISDVKQHLKRRHTFNYSCTRCFEGFSSSKEYEGHVLEQACPIVECNNNDSVSPTAQEALKYRVDRSSSSQVQWHEMSRILFGKLGLSLNPYQDGVFKEITGIIRGIWKNEGQNIISSLRDTRNVPCADQLRPLLSEILARVEDCFEKKEQKPSKESPRERSESNQGTPTRTPEEGKLEHDCQPFSGLSTIKNVCGPLEINESHNLPMQDWSYATGLDTSNNIFNHTMLPEYQNHQVGCPFMNLSAGLLHPDDGRNWQFMGPNSITVMENIMAHQVSMGDFPFTDSDLLSAQTPNLYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY03</accession>
    <name>X0CY03_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK99400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY03"/>
    <dbReference type="HOGENOM" id="CLU_3260602_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="42" mass="4699" checksum="B76E5F18FFC949C3" modified="2014-05-14" version="1">MSNNEKQQIAEEFSAARRVRQPASQVAMDSAPQSTFMCPRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYU9</accession>
    <name>X0CYU9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Syntaxin 1B/2/3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_03228</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYU9"/>
    <dbReference type="OrthoDB" id="10255013at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15849">
        <property type="entry name" value="SNARE_Sso1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.70:FF:000008">
        <property type="entry name" value="Syntaxin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF380">
        <property type="entry name" value="SYNTAXIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="217"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK96044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="469" mass="52479" checksum="BD1BD5676A13263E" modified="2014-05-14" version="1">MSYGYGGQNPYDSPDQGYGGNNGYGNGGGYNSPPAQGYGGSVEMAPLAHNAGGFGQGDPNAILNECRDIDRGIDTVEQNLEQLRMIQQRTLDDADSSGSSAASRQLDSLSADTMSLYRELTERVRTVKSNPEAKSPKNNPHVTRIDRRLKAAITQYQQVESQFRKRTQDQMARQYRIVRPDASEQEIQAAVEDTTGGQVFSQAMMQSDRQGRARAALSAVQDRHQALIKIEQQMVELAQLFQDMDTLVVQQEAAVTQIEQKGEEVVENLDKGNEEIGVAVNTARKTRKKKWICLGICGMYLRPQLDVRHLTNLSSCYHCCYCHYCSHLHLRHQGTEQQQQEAKYRGSHWQLARYAHSCPTCSLSPSCCCRQHSILSAQQCWRRAVPSTSATAELGRSRTMREWLGGDCLRMTTRRYLYSLRNIYALQRSGPGSCGGKSSVRAVFVFCVFPLDLDHNCCYSPIARLFSLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ47</accession>
    <name>X0CZ47_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ47"/>
    <dbReference type="eggNOG" id="ENOG502T5A1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092154_0_0_1"/>
    <dbReference type="OrthoDB" id="5075004at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022085">
        <property type="entry name" value="OpdG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12311">
        <property type="entry name" value="DUF3632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK96578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="299" mass="34050" checksum="72B5AF6B1FCFD0BD" modified="2014-05-14" version="1">MTEQQESSDSPRWLKYIEEMIEEEEDEVDSEAIYYEIVRDLLLSEQDLDKAVSEAIQRFYDHYVAGFSEEDLGGREPPEYDAGGYLNSIAVIVFELVAKIPFTDPKQDMLSKFLIGIAKNAADSFDEKNPRFVCWSWGIQAAAVERWNACHIDAGRLDREGPAVDGAIDIWLSTTALIAKLFQADLLGAYGPLWLTHDFIRAFKTHTDGDYTKHPVRQAQILAVANYILLAGEAFAQDAKISSPERRYDLDAENWKLWASKLKEISDTVNEDVRWDLKGKTQKAYEKMVELYPEAFSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ50</accession>
    <name>X0CZ50_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_00195</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Is probably involved in a pathway contributing to genomic integrity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IRC22 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ50"/>
    <dbReference type="eggNOG" id="ENOG502S7BF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068820_0_0_1"/>
    <dbReference type="OrthoDB" id="1926781at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005595">
        <property type="entry name" value="TRAP_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924:SF0">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03896">
        <property type="entry name" value="TRAP_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937329" evidence="11">
        <location>
            <begin position="21"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="207"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK99795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="265" mass="28742" checksum="0D928751F0BFF4C8" modified="2014-05-14" version="1">MFFKASLLALVAAQVFGAAAQDAPEANAAPKAPLKADIKATFPEADILGVKLVNGRPTKAVIEINNKDANAINVAFVAGSLNTMKELPEDSPRYASIVRNLTSVQYNIEVPAGEKKELPFSFAQDMQPQEVRVELSAVVTDSTGNLHQVLVHNGPASIVEAPTSFLDPQIIFLYLFLSAAFAGTLYFVYKTWIEALFPQAKRPRTNKKAKKTIDVAEPLSGSESTPVAVPSGKDYDESWIPDHHINRPIARRVKSGASAKTKRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ58</accession>
    <name>X0CZ58_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoribulokinase/uridine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ58"/>
    <dbReference type="HOGENOM" id="CLU_067202_1_1_1"/>
    <dbReference type="OrthoDB" id="6362633at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="229" mass="25938" checksum="7CC4A7104BE261FC" modified="2014-05-14" version="1">MDVIYAQLERRALSLLEQSHQQSSDARAIIILAGPPGSGKSTIASQVVQRINARHRTPIAKILPMDGYHYSRSHLDSLPNHVEAHARRGAHWTFDGQAVLDMIKQLHASRERPFTTLYVPSFDHEIKDPVPGAIDISPDVKIVLVEGNWLLYNEHPWNQIVNYADDTWFVDVDPQLAFRRVAKRHVASGIEKTLEAAMDRARNNDMKNGEDIRRCLIQPIIEVESVEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZR2</accession>
    <name>X0CZR2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_02198</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15245"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. Lipase family. Class 3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZR2"/>
    <dbReference type="SMR" id="X0CZR2"/>
    <dbReference type="eggNOG" id="KOG4569">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032957_1_0_1"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF11">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012226763" description="Fungal lipase-type domain-containing protein" evidence="4">
        <location>
            <begin position="16"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="5">
        <location>
            <begin position="106"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00043996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00047591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK96773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="346" mass="36549" checksum="46090092E1B44367" modified="2014-05-14" version="1">MLLLPLLSAITLAVASPVALDDYVNSLEERAVGVTTTDFSNFKFYIQHGAAAYCNSEAAAGSKITCSNNGCPTVQGNGATIVTSFVGSKTGIGGYVATDSARKEIVVSFRGSINIRNWLTNLDFGQEDCSLVSGCGVHSGFQRAWNEISSQATAAVASARKANPSFKVISTGHSLGGAVAVLAAANLRVGGTPVDIYTYGSPRVGNAQLSAFVSNQAGGEYRVTHADDPVPRLPPLIFGYRHTTPEFWLSGGGGDTVDYTISDVKVCEGAANLGCNGGTLGLDIAAHLHYFQATDACNAGGFSWRRYRSAESVDKRATMTDAELEKKLNSYVQMDKEYVKNNQARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0D008</accession>
    <name>X0D008_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D008"/>
    <dbReference type="eggNOG" id="ENOG502R9DY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041437_1_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="42052" checksum="B4483110FB311C99" modified="2014-05-14" version="1">MVPLFSPSGFGRFKDSHSRLTASASQKSVPSPMPSPMPSPMPSPSQPSPEPMATVLIGPKQQRFKVNKRLLCATSPFFADRFGDPSSSKSISLWLPRESSSMFGLFVDWVHLGLRFRPHLDEMISNAYDAGLEASQNIHWSLIRLHLFASRLGLYRLQDLAMDSIQDLYLRCDWDVPSGLITFLYTECEDLAAIRLRRWAVAMVAFSFTGGPRLTFHPQQSATSEPTRFSDLLEELPEFASDYDIHMEKMRLSGLDIRFKNPQLRIPANRLRNDERAFGFRQCSFHSHRSSVGERRCPHESGSTKHRRVYQSSVKESGPESTGLSAPTRRYRDVVPRPLFSGPMDSDIGEDDDDEISKAIKHVRSISSTLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D048</accession>
    <name>X0D048_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Translation initiation factor 4E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_03504</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least eIF4A, eIF4E and eIF4G. eIF4E is also known to interact with other partners.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D048"/>
    <dbReference type="eggNOG" id="KOG1670">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043552_2_2_1"/>
    <dbReference type="OrthoDB" id="590761at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.760.10:FF:000004">
        <property type="entry name" value="Eukaryotic translation initiation factor 4E-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019770">
        <property type="entry name" value="TIF_eIF_4E_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF8">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00813">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00062860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK96489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="256" mass="28611" checksum="014FA20929299E92" modified="2014-05-14" version="1">MAAAVADTPKMDEQVDLTTIPVDPAGKEDSSDVKDDDKPVTVFHDKDNFNVKHPLQNKWTLWFTKPPSGKGDNWNDLLKEVITFDSVEEFWGVYNNVAPVSELSLKSDYHLFKAGVRPEWEDPQNKHGGKWSYQYKDKRNIDVDRLWLQVMMAAIGETLEDEDDGEVMGVVVNVRKAFFRIGVWTRTIGKSIPGRGEGDVAGGKGRSGEKGKEILLSIGRRFKEVLELPASEQVEFSGHTDSAHSGSTRAKAKHVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0S1</accession>
    <name>X0D0S1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0S1"/>
    <dbReference type="eggNOG" id="ENOG502R12D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1209871_0_0_1"/>
    <dbReference type="OrthoDB" id="5056824at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="229" mass="24453" checksum="BB5FF16A90A938D8" modified="2014-05-14" version="1">MPHPRIPGFAALKRANKLNDQEARPEIQEKGISLVESLSLRGVTTEKTSGLRIVNNSPGGGRQENVVAKVPGLEGTYAAVIDNQDSLLEAYRMMTRGRLSVIFAVPPNGSGASMTTAEIPWSVLKASEEAAPSQTEEKEKDDEEDSATIVADDETVIGDDESTGKVAKKAKNEASPQKTTANHDNQPGNDADVPYPDLAGLGMNAECAHQRTQIQCSIRTDPETETIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2J4</accession>
    <name>X0D2J4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Insulysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_00711</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2J4"/>
    <dbReference type="MEROPS" id="M16.008"/>
    <dbReference type="eggNOG" id="KOG0959">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004639_1_2_1"/>
    <dbReference type="OrthoDB" id="952271at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000003">
        <property type="entry name" value="Insulin-degrading enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000005">
        <property type="entry name" value="nardilysin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000004">
        <property type="entry name" value="Putative insulin-degrading enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050626">
        <property type="entry name" value="Peptidase_M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032632">
        <property type="entry name" value="Peptidase_M16_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054734">
        <property type="entry name" value="PqqF-like_C_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690:SF18">
        <property type="entry name" value="INSULIN-DEGRADING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690">
        <property type="entry name" value="NARDILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16187">
        <property type="entry name" value="Peptidase_M16_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22456">
        <property type="entry name" value="PqqF-like_C_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="8">
        <location>
            <begin position="50"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="9">
        <location>
            <begin position="225"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 middle/third" evidence="10">
        <location>
            <begin position="401"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="Coenzyme PQQ synthesis protein F-like C-terminal lobe" evidence="11">
        <location>
            <begin position="797"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="947"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="952"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXL00632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1013" mass="116390" checksum="9B93C4B0612165A6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0D4N0</accession>
    <name>X0D4N0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D4N0"/>
    <dbReference type="eggNOG" id="ENOG502S4EJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015639_2_0_1"/>
    <dbReference type="OrthoDB" id="5428040at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="616"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK89612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="711" mass="78481" checksum="F92B2D794BAA4FFE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8U2</accession>
    <name>X0D8U2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ino eighty subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_00332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8U2"/>
    <dbReference type="eggNOG" id="ENOG502QVDM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007606_1_2_1"/>
    <dbReference type="OrthoDB" id="5413003at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038014">
        <property type="entry name" value="Ies1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37287">
        <property type="entry name" value="INO EIGHTY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37287:SF1">
        <property type="entry name" value="INO EIGHTY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK99988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="661" mass="74529" checksum="9A06899835EF911D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>X0D988</accession>
    <name>X0D988_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Methylenetetrahydrofolate reductase (NADPH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_00429</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D988"/>
    <dbReference type="eggNOG" id="KOG0564">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025841_2_1_1"/>
    <dbReference type="OrthoDB" id="16284at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.220:FF:000002">
        <property type="entry name" value="Methylenetetrahydrofolate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004621">
        <property type="entry name" value="Fadh2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00677">
        <property type="entry name" value="fadh2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF1">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="10">
        <location>
            <begin position="410"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="339"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXL00134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="673" mass="75076" checksum="49305EA85182396C" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0DC42</accession>
    <name>X0DC42_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DC42"/>
    <dbReference type="eggNOG" id="ENOG502R26A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2264355_0_0_1"/>
    <dbReference type="OrthoDB" id="4761172at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL00660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="98" mass="10923" checksum="B78490D098039560" modified="2014-05-14" version="1">MSSKSWYTLKSKAVHTRYGLTKNIQVLLQGLESFHAGVIDARELGSMVRLSPRRRESVAATIAKCARMINKDPQESKTCVDIIEMCTEILEIAGKQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0DD85</accession>
    <name>X0DD85_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_00939</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL01075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DD85"/>
    <dbReference type="eggNOG" id="KOG3406">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110343_0_0_1"/>
    <dbReference type="OrthoDB" id="10249311at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000005">
        <property type="entry name" value="40S ribosomal protein S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000530">
        <property type="entry name" value="Ribosomal_eS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047860">
        <property type="entry name" value="Ribosomal_eS12_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11843">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00972">
        <property type="entry name" value="RIBSOMALS12E"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01189">
        <property type="entry name" value="RIBOSOMAL_S12E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="5">
        <location>
            <begin position="30"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXL01075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="146" mass="16179" checksum="CECDF0BA6A705447" modified="2014-05-14" version="1">MSDVEDNTPEVADVVEVSGDAPKGQMSILDALKGVLKLSLMHDGLARGLREASKALDRRQAHMCVLNENCEEEAYKKLVVALCNEHNIPLIQIPDGKQLGEWAGLCVLDREGNARKVVNCSCVVVKDWGEESQERSILLNYFQTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0DIU5</accession>
    <name>X0DIU5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DIU5"/>
    <dbReference type="eggNOG" id="KOG0274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009186_0_0_1"/>
    <dbReference type="OrthoDB" id="2095648at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF2">
        <property type="entry name" value="F-BOX AND WD DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11400)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="122"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="971"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="971"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1073"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK94307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1123" mass="122750" checksum="8D4366CE8DFB6F8E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0DJ48</accession>
    <name>X0DJ48_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="5">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_04497</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="5"/>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DJ48"/>
    <dbReference type="eggNOG" id="KOG0856">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_8_1_1"/>
    <dbReference type="OrthoDB" id="44061at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00357">
        <property type="entry name" value="peptide-methionine (R)-S-oxide reductase MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081:SF8">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MsrB" evidence="6">
        <location>
            <begin position="66"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK94417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="202" mass="22368" checksum="4CE1A4E0C3B6DD1C" modified="2014-05-14" version="1">MRFSPLLSTLFYTFSNITRVRTPLPSHLAFRPIPLRSMSGIPLLGALFGTSSKNSSNMSYPDQRTNDEWRAVLNKEQFRILREKGTEPPGSGKFDKHYPEQGVYTCAGCDAPLYKASHKFSSGCGWPAYFDSIPGAVVRHEDRAFGMARTEIVCANCGGHLGHVFKGEGFDTPTDERHCVNSVSLSFSPDDKTVKDKPESKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DKZ4</accession>
    <name>X0DKZ4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DKZ4"/>
    <dbReference type="HOGENOM" id="CLU_194712_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="58" mass="6436" checksum="CBB8711FAFB3B46E" modified="2014-05-14" version="1">MPDARCQVQQGRCPPIQILGKRNSDEHPFARSASPGQATGGGWKWVSECHGFRRQAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0DN31</accession>
    <name>X0DN31_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DN31"/>
    <dbReference type="HOGENOM" id="CLU_3191350_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="46" mass="5313" checksum="0A70CF36D82FEC66" modified="2014-05-14" version="1">MSDSHMYGQVDLNVDWYAQPDVSTQDIVVLMQEGLLLQDFELKIVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0DS37</accession>
    <name>X0DS37_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylglutaconyl-CoA hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02412</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DS37"/>
    <dbReference type="eggNOG" id="KOG1679">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000058">
        <property type="entry name" value="Enoyl-CoA hydratase/isomerase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF171">
        <property type="entry name" value="SD19268P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK97087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="362" mass="39293" checksum="21346AADA7612B7C" modified="2014-05-14" version="1">MNRHQPMHVIPRLAVPPCPRYLNIQSFNFPPPISIQRSPIDLLKMAPRLSQPVVTLRLLRRYYSSATEPLIRVTNLPAPNTGHIRILELNRPSARNAISKALLANLRAEIDAVHIQYGPNGEELPLQKRFGGAAGVDEKGPTRAVVLASAVDTSFCAGADLKERKGMSQGETAEFLTNLRNTLTSLSNLPIPTISAISSVALGGGLELALSTHFRVLSSNATVGLPETRLGIIPGAGGTHRLPALIGLSRARDLILTGRRVGAPEAYFLGIADRLVEIVPEDERDGSDVLGEARKAALSEAVRLAQEICEGGPIGVRAALQAVAWAREEVENKMYERVVNTEDRNEALKAFQEKRKPIFTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0DV73</accession>
    <name>X0DV73_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DV73"/>
    <dbReference type="HOGENOM" id="CLU_1315451_0_0_1"/>
    <dbReference type="OrthoDB" id="5100807at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="233" mass="26201" checksum="42ECA313CB7DCACC" modified="2014-05-14" version="1">MVTKEYPSLCVPDVSASDDSEGTVPIQSCEVNSHAMTKPQHRNIVKANTGMARPREIGLARVRVDVLSIAGTSRAQRLSKSPELSDNISEDTQDELERPSLEESKEQQAESGPPKSCDYVASTRDSGETREASPSANPDRDQPDNPDGGNHDMNEDRTLQPQNNIFDARGIGRPPRFACPYQAFEQFQVCFRPGPRNPNGGCASIQRLKQHLYRRHMRPYRCTRCWQSFEKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0DV90</accession>
    <name>X0DV90_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Autophagy-related protein 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Autophagy-related E2-like conjugation enzyme ATG3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_01136</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DV90"/>
    <dbReference type="OrthoDB" id="1584384at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044804">
        <property type="term" value="P:nucleophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK98127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="368" mass="41722" checksum="2F530287687BFC96" modified="2014-05-14" version="1">MNYIYSTVNTLRDRYTPVSHKSTFRQTGQITPEEFLAAGDYLVYKFPTWSWGDADSPEQRVSHLPPGKQFLVTRNVPCHRRLNDDFAGDAGHEEALVNDGDDFKGATGDDEDGWLRTGGLASSQPLKVKEVRTVDDSGNVGDREVVEDDDEIPDMEDEDDDEAIIRDSSADSKNSAHRTYTLYIMYSPYYRTPRLYLSGYLASGQPLPPNDMTEDIVGDYKDKTVTLEDFPFFANNIKMASVHPCKHASVMKTLLDRADAALRLRREKLRAGNSQTPSGMEGLVDEIGKLDVKGAQEAADKDEWEEVQETEIDDQEVAIRVDQYLVVFLKVRLSMLRGIILHFLTLFLVHGQCDTWYRARFHHGCLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0E118</accession>
    <name>X0E118_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DSC E3 ubiquitin ligase complex subunit A</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Defective for SREBP cleavage protein A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">RING-type E3 ubiquitin transferase dscA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">FOQG_00370</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">54005</strain>
        </source>
    </reference>
    <reference evidence="24" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalytic component of the DSC E3 ubiquitin ligase complex which is required for the srbA transcriptional activator proteolytic cleavage to release the soluble transcription factor from the membrane in low oxygen or sterol conditions. Required for growth during hypoxia and triazole drug susceptibility, as well as for virulence in a murine model of invasive pulmonary aspergillosis (IPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the DSC E3 ubiquitin ligase complex composed of dscA, dscB, dscC and dscD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E118"/>
    <dbReference type="eggNOG" id="KOG0828">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010475_0_0_1"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044695">
        <property type="term" value="C:Dsc E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000626">
        <property type="entry name" value="Transmembrane ubiquitin ligase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021319">
        <property type="entry name" value="DUF2921"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF162">
        <property type="entry name" value="TRANSMEMBRANE E3 UBIQUITIN-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11145">
        <property type="entry name" value="DUF2921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 22" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738295" description="DSC E3 ubiquitin ligase complex subunit A" evidence="22">
        <location>
            <begin position="24"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="473"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="598"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="622"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="652"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="684"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="23">
        <location>
            <begin position="772"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="504"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="516"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00056116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00063126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00071072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00077885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00082128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EXL00038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="836" mass="93197" checksum="634E71432333E56D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0B5F3</accession>
    <name>X0B5F3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658618">
        <property type="protein sequence ID" value="EXK77345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B5F3"/>
    <dbReference type="HOGENOM" id="CLU_2904297_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="62" mass="7170" checksum="EBB9B051D853CD78" modified="2014-05-14" version="1">MMTLTAKMRYEYPHEPTDEDVAVRPTGWTASILPIRKKGWKPLSLEVLTGKNDTRRETPTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7K7</accession>
    <name>X0B7K7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17567</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979377">
        <property type="protein sequence ID" value="EXK77731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7K7"/>
    <dbReference type="eggNOG" id="ENOG502QRX5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019533_1_2_1"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF62">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="97"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="458" mass="51033" checksum="EDDC4F6F336D3178" modified="2014-05-14" version="1">MSLGCNSTPFRSSGSYLASTSHANSTEDLVRPSLAAQSSTQSSLKKGFPQRPYFHSRRVKKGTVERPYLAVKDPRDIWITVIPALGIVVGLAAIALLSWSGYRSVDKHEYCKVFTDDFSNGFNSTIWNKQVEVGGYGNGEFALTTDTDENVFVRDGQLIIKPTLQTDKFLSETTKINLTAHGTCSSTTTQDCVQVANLTAGEIVAPVKSGRITTKNFGVIRYGRVEIVAKLAAGDWLLSQLMMFPAKEYYGAWPASGEIDIGMVRGNNYTYDNGRGNQQVSTQLHWGLDTSTDRWQSTSGVRNALLTTFNRDFHTFGLEWSDKYLFTWLDHRIAQVTYVKFNHPFYQHGGFHQALANGSQISDPWSGPGTSNATPFDRPFYLIIALAVGGTSGWFPDDVHSKPWVNDAISPRKDFWNAKDRWYPTWEENSGGEMVIKSVSMWQQCDRAATDLSHFSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAD7</accession>
    <name>X0BAD7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979820">
        <property type="protein sequence ID" value="EXK75778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAD7"/>
    <dbReference type="HOGENOM" id="CLU_088300_0_0_1"/>
    <dbReference type="OrthoDB" id="4725912at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="195" mass="21494" checksum="4DDF73BBF7D8FA65" modified="2014-05-14" version="1">MNELANKLLHYTSSLTSGTQPNPTHHFILRRSSQDSDITNVSPIDQPQDGLAVYTIQTSKKTIILYQGEPNPQQVVGECKAAFMGLSMNVSLRGSQFLIRNSTTGTKFVVESPNYDRLTWRGDSLLGSGLSLYKATGEKVATIKSGGILNHHEKQLLLFMPCDVNYVEMVLLTAVAAMKLDKRADDIAYKLLSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAR2</accession>
    <name>X0BAR2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658498">
        <property type="protein sequence ID" value="EXK78856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAR2"/>
    <dbReference type="HOGENOM" id="CLU_1124596_0_0_1"/>
    <dbReference type="OrthoDB" id="4988718at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="247" mass="27824" checksum="AEE926601A6CFD4B" modified="2014-05-14" version="1">MQPPPSRNVDTRILIQPSFVMHSGPSRVFQVYVPATDNARFNEIEEHYKRNGRYCGICGTWKLNLNSHIIDQHSGSKHAVIYNGEATRDKTKGLLQRRRDRRSKETFPPKLLALVRQMKNSLPPLVRHFGGRFEKGPLQGQEVTGLPQFFEKSSGRLKSCYMDLVQGTEVHPQTRSKARRACNIPPAGSFRNKLWIGGSGLSVVTMVSTNVWTPDKYPDWTGPPGFLAGEDPTWIPCDLPSDRNGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB77</accession>
    <name>X0BB77_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_16324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658486">
        <property type="protein sequence ID" value="EXK79031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB77"/>
    <dbReference type="HOGENOM" id="CLU_2197127_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK79031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="108" mass="11643" checksum="95F35A9D629C30C9" modified="2014-05-14" version="1">MPLQSVLPKGSWILVTGATGFIASHTVKTLLDFEYKVRGTVRDREQASWLLNIFPTNFELIEVKGSISAIKGMSAAAHVATNNESIADPNMVIPQTVKGVTSMLEAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>X0BCE4</accession>
    <name>X0BCE4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_15926</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658470">
        <property type="protein sequence ID" value="EXK79456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BCE4"/>
    <dbReference type="HOGENOM" id="CLU_010813_3_0_1"/>
    <dbReference type="OrthoDB" id="4116913at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK79456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="510" mass="57250" checksum="109C94BBB616E99A" modified="2014-05-14" version="1">MRNRRACDACRQRKIQCDSDASSPTQQCNWCSCHGMICTFHGLRTKVLKSLPSLECKDGRPGSSERAENNPSSDGIGAKSELQSIPCHPRVVNWVAPKGSPTLYAGLLMGQNRCHTGIPFFTKGDEEWINSRTGGEANFQIFTALRMRQQTQLSDSPHIPAHGANGDLGVLPSRGITKAFLDAFHQSFLRLVFPVVDYTLFQETIAAAYEASDALSSPKQTAAKVCVLAFISMVGVLFHGKLSFLPAMDWDACYHAARSFLPNMLDEATLENLQTVLMLYLRQRYIGHSESSVILHSIACRMAFILGGNTYTETQAFRNEITNQERQIRHIRLLFWHCYIFDKDIALRTGQPPFISDMNCDLTLPKGYVETQFVPPLPGHHVSSSYYADESLVPFLPGELRLSMLKHKTYELLYSTKALAKLNSEIIRAILELDDELESWRLSIPKVVRPALSVSDVKQALSELPIQHRMQNIVLHLEYHYLVVTIHRAGARCIADDSDKSSTHVTDPPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDA7</accession>
    <name>X0BDA7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylosidase/arabinosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_18777</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979500">
        <property type="protein sequence ID" value="EXK76479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDA7"/>
    <dbReference type="HOGENOM" id="CLU_114415_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052176">
        <property type="entry name" value="Glycosyl_Hydrlase_43_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772:SF2">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK76479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="20544" checksum="1D6390468970662E" modified="2014-05-14" version="1">MVGGTDDEEIVSNQSIDPAAFEDPETGKWYLCWGNGVPVVAELNDDMISLKADTWHKITGLEDFLEGLFVNYRDGTNHQTYSNDDTGSENYRVGYATADNPIGPWTYRGVILQKDESLGILGTGHNSVMNIPGTDEWYIAYHRFHIPDGGGFRRETTIDKLPIDKDTCLFSSVKPTLEGVGPRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BDI7</accession>
    <name>X0BDI7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diaminopropionate ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979483">
        <property type="protein sequence ID" value="EXK76559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BDI7"/>
    <dbReference type="HOGENOM" id="CLU_2740120_0_0_1"/>
    <dbReference type="OrthoDB" id="10059875at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="85" mass="9443" checksum="64B616AD38D6BC7E" modified="2014-05-14" version="1">MMKNLGAIVARVARMNGWRFVSSTSWSEFDNSIVQNVRNAYMVVVEEALQVILAVENIMHAFVCGGVGSIAAAVFHGFFTRFCRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFF1</accession>
    <name>X0BFF1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658434">
        <property type="protein sequence ID" value="EXK80870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFF1"/>
    <dbReference type="HOGENOM" id="CLU_492601_0_0_1"/>
    <dbReference type="OrthoDB" id="5115443at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="564" mass="62626" checksum="4CFAB2A738765846" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGB3</accession>
    <name>X0BGB3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Monocarboxylate transporter 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_17760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658595">
        <property type="protein sequence ID" value="EXK77529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGB3"/>
    <dbReference type="HOGENOM" id="CLU_008497_2_0_1"/>
    <dbReference type="OrthoDB" id="10056939at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="96"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="98"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="45"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="222"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK77529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="815" mass="91499" checksum="85A9A1DF0DDB8928" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJH9</accession>
    <name>X0BJH9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658415">
        <property type="protein sequence ID" value="EXK82300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJH9"/>
    <dbReference type="eggNOG" id="KOG3043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_2_1_1"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="247" mass="26950" checksum="09499F7B76C454E9" modified="2014-05-14" version="1">MASHPPAACCTIANLHEGTPKGDIVKVDNVTGYLAKSSKESKQAVLYLPDIFGIWQNSKLMADAFAAEGYTCLVVDTFNGDPVPLEMPEGFDIMKWLGEGSDGKNPHTAEAVDPIVVSGIEYLRSIGITQIAAVGYCLGAKHLIRHYKDGINVGFIAHPSFVESEELAAITGPLSTAAAELDDLFTVEKRHESEGILSKSKQDFQINLFSGVHHGFAVKGDMKDKRQLFAKEQAFNQAVSWFKRHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJY7</accession>
    <name>X0BJY7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_16216</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="JH658479">
        <property type="protein sequence ID" value="EXK79168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJY7"/>
    <dbReference type="eggNOG" id="KOG1383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019582_2_2_1"/>
    <dbReference type="OrthoDB" id="5152799at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000017">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.50:FF:000001">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF6">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK79168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="509" mass="57580" checksum="85272CEAD9A9ED51" modified="2014-05-14" version="1">MGHLSVVHTARSRGSGASQVQLPDKEDVFTTASYGSRFARMELPRHQMPESEMPRDTAYRLIKDHLSLDNNPTLNLASFVTTYMEDEAQQLMSEAFPKNFIDYEEYPQSADIQNRCVSIMGNLFHAPAGLSVGTSTIGSSEAIMLAVLAMKRRWKARRLAEGKATDSPNFVMSSAVQVVWEKAMRYFEIEERFVYCTSDRYVLDPAQAINLCDENTIGICMILGTTYTGEYEDVKGLNDLLIERNIDIPIHVDAASGGFVAPFIIPDLEWDFRCEKVVSINVSGHKYGLVYPGVGWVIWRAPEYLPQELVFNINYLGANQSSFTLNFSKSASQVIGQYYQLIRLGKHGYRSIMSNLTRNADYLAEAIEKQGFLIMSERNGRGLPLVAFRFRTLEEGGEDRHYDEFALAHHLRCRGWVVPAYTMAPKSNVKMLRIVVREDFTRSRCDSLIEDLLICHRLLKDMDQETAKMLQEHINKHVTSTGKGEKAHPVYANETHSLQGKTGKTHSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BL73</accession>
    <name>X0BL73_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658477">
        <property type="protein sequence ID" value="EXK79189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BL73"/>
    <dbReference type="HOGENOM" id="CLU_061834_1_1_1"/>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040:SF1">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="1">
        <location>
            <begin position="51"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="267" mass="30177" checksum="42100CCED1E08842" modified="2014-05-14" version="1">MPDMASNLDTVTQRLSTAKLEDKPAIIFVNNATAIAQLVDSLDGPPAVPPSIFIDLEGVNLSRHGTISIMQVYYLPTKCTYLIDVYTLRDECFSTPGRNGRTLKGILECDSIPKVFFDVRNDSDALYGNYQIRLAGIYDLQLMELATRSFSRRCVNGLSKCIEQDAPMSIQERLDWVQTKEGGLRLFAPEKGGRYEVFNERPLPDAIKFYCAQDVQILPRLWAYYDGKMGQRWRERMIAESRARVQSSQSATYNGKGRHMALAPTGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLA3</accession>
    <name>X0BLA3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658465">
        <property type="protein sequence ID" value="EXK79658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLA3"/>
    <dbReference type="HOGENOM" id="CLU_044860_0_0_1"/>
    <dbReference type="OrthoDB" id="3485856at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="400" mass="45501" checksum="2166B38A0814158B" modified="2014-05-14" version="1">MENGREASGELPSLETGPQQQYFKSPRKVTPPERNALPSPPATIEVERIRNPPNLPQRLLDFKRKAETCDVAPLTYIPLSPAEYASACEQIDSAFKRFDYDPKRGLIILRMTSPTHDTFVYSLSRSIDQEIQRVGRDNSQVRGFTSQIEGGGSSRIYLGDKEKQDKIPKCLRRQPDGQFRLEGAEFPGVVIEVSYSQDGKQLSKLAKQYINYSEGNIKVVICVDINYGNTQSTLSLWKSQFNPDPESNDPDDYILDYEQAIEAQPFRTADGKPLNPESTLTLYLHDFAPDQSCQDIPNIPISISFAKICEFLDRAEKGQKDRESKDARGIRSTRKVRKRKVSSSSLEELALDDEERFKKQENAVDTRANHHDDDFEPRLGDVNVTYRDHDLRPRAAKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BLC3</accession>
    <name>X0BLC3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658475">
        <property type="protein sequence ID" value="EXK79264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BLC3"/>
    <dbReference type="HOGENOM" id="CLU_041690_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="375" mass="42319" checksum="854A5E826F1D91DB" modified="2014-05-14" version="1">MAEFLRLSSNAWINQKPAEEATSKPNRNQDRRDELDGLREELSQVEKNIMYFTSTFPPPSGQPFSTVMEERFLGKVPVTERLKLLIERVRHRIDDLQSSLAQAKLDYERVIRPERAPSAFVPDTNEVVTPLSELNMEFLIPTDRGSGAIHSPTGQRQSRSIDGKHNADASHEGHVPLEKPLSSLRSCDISASTQTGIQEASKESRVEGHGGLMHASTDRPMGSRKLEEEHALGSDSVRTDLERLRASLIFHLCTMLFASKRTVDVERLREGSRIFSRRTIGKGNLELLEQVIKGYSEKSMKSRGANKELRKITYKGRKAFPDTLLKTYTTIFKTLLTLTQNLDINDPIIDSRRTKGLEAARLDKGTKIQRRTGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMA6</accession>
    <name>X0BMA6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_15794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI979344">
        <property type="protein sequence ID" value="EXK79609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMA6"/>
    <dbReference type="eggNOG" id="ENOG502RKE6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030671_1_0_1"/>
    <dbReference type="OrthoDB" id="5396at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF11">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35372" checksum="15A2D20E7F3FDD00" modified="2014-05-14" version="1">MSSKPSFKSLPLRKDGPPGNAWGLFGDNDECGMLNLLTPEIIAKAASEIRDGVRVSTDWPLNRMSRPCFGRAPFKHEITTKTPRAVNDDTLTFNTQSSSQWDGFRHYAYQKEKLWFNGKSLDELLSSDVNGIQAWVDRGGIVGRGVLLDYASWADKNNITLTPFETKSITVSTLKEVAESQGTTFQQGDILFIRTGWVRAYDKLSDDECKTLADYKVPPAHGIESSEETLRWLWEQDFAAVAGDQPSMEAWPCQNTDYFLHEWLLAGWGIPIGELFDLEALSKECEKRGRWSFFFSSMPLKVPGGVASPPNGVAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMA9</accession>
    <name>X0BMA9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_15389</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI979341">
        <property type="protein sequence ID" value="EXK80038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMA9"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_4_1"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF139">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="439"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="507"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="59"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK80038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="548" mass="59717" checksum="AC58BE6636FB758B" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMN6</accession>
    <name>X0BMN6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_15734</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658463">
        <property type="protein sequence ID" value="EXK79709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMN6"/>
    <dbReference type="HOGENOM" id="CLU_064755_0_0_1"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="250"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK79709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="345" mass="39044" checksum="9308C4841830E27E" modified="2014-05-14" version="1">MDDSFSLFNQPMPCPSTTTSFSSASSAYDPFTPTSRRSTPHEIGNMDFDGPYNSISHPVEFDPPFEFTFGPVKPEPEHISFSDSLPNTPMKREQLGFESEHMIDMNMAHHGPMGSLTPSNSFGMSPYSPDASMGPASFMMTPTQSISGSEAAETGTSWSCANDSTISFFFNRQLSSKFDTLDMDRHSQSPIGYHLHDSNSPNRMRAQRKVMVHEIQQKSAELQRAQIRSSRKRSIKPDSAQVDVVRRAMCKCDYPGCDKAFRRNEHLKRHKQTFHGEGPNRFSCEFCGKDQFNRQDNLNNHRKLHARPNSRNRGVEFIPAAVPVIEQEERIRKQRAPSKSKIAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BMT4</accession>
    <name>X0BMT4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_15651</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658460">
        <property type="protein sequence ID" value="EXK79774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BMT4"/>
    <dbReference type="HOGENOM" id="CLU_028200_3_5_1"/>
    <dbReference type="OrthoDB" id="10017208at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF167">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="42"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="300"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK79774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="370" mass="40396" checksum="19557D4E4C704D4C" modified="2014-05-14" version="1">MPAPPPSFVVNTNPERVAESQTALIIGVIAAVNLLALVVVAARTYTRLAISKSPGAQDVLMVLSACTGLVGTIILFMQISYGLGKHADTIERPDYATFGKYSFIHTVVSLLGGIGLLKIAIALELIKYNGNSGRWYNITLWCLIAFVIAYTFEAWMSFILFCKPVAKQWDRSLEGSCYPVSMFVVFGLANSAFNIFTDVAFATLPIPIVWSLKMPLKTRIYLVVVLSLGYIAAVMGLVKAISQIKYDPAGDTTYLYDVQFWGLLQLNVGTIAACVPSLRPLVKNILRLKSLTPVYGYTNSGQRQRSMPLSTIGVGGAKSTSRRGQPAFEPNDRHDRKNGLSSNAGYGDTVFELKNSSQVAILETDSTERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNP4</accession>
    <name>X0BNP4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ethanolamine kinase</fullName>
            <ecNumber evidence="3">2.7.1.82</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_12177</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.82" evidence="3"/>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNP4"/>
    <dbReference type="eggNOG" id="KOG4720">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012712_1_1_1"/>
    <dbReference type="OrthoDB" id="10267235at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF66">
        <property type="entry name" value="ETHANOLAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK83476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="366" mass="41136" checksum="E1858642F6F06962" modified="2014-05-14" version="1">MDIPFKDVVFDTSDPHGSALSLLPLLFPDRKIDDMRISALTQGTTNGLFKVTIDASTADAVLIKVYGDGTDITIDREKELRVHKLLAERQLSSSPLVRFNNGHAYQFISGRVCSEGDMSETRIFRGVARELARWHATLPTADAKEVLTYKPGVWSTAKKWLDAISKHPHRSKAEIDDLHEKFKYLADNLLSTDMSEPLVLAHGDLLCANIIAQESGDGIDVASVRFIDYEHATYCPRAFELANHFAEWTGFECDYTLLPKTSTRRAFIAEYLTTHAELCRGHNTDVPTVNDASVDHLMRQVDDHRGFPGFYWGLCALIQAETATGTIDFDYAGYAAKRFAEYEDWRSVREGNSPSLPLREKVWSMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0BP66</accession>
    <name>X0BP66_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_11716</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">54005</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK83985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK83986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BP66"/>
    <dbReference type="eggNOG" id="KOG4231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_475828_0_0_1"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07216">
        <property type="entry name" value="Pat17_PNPLA8_PNPLA9_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="12"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="4">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="55"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK83985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="567" mass="64942" checksum="81BF9473C6428867" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQ96</accession>
    <name>X0BQ96_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQ96"/>
    <dbReference type="eggNOG" id="ENOG502STGX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052068_2_0_1"/>
    <dbReference type="OrthoDB" id="5343483at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="299" mass="34267" checksum="CFA3E190871E167F" modified="2014-05-14" version="1">MSPSPNQSLHRLSVENSWFATRPILWTSQHLNLMGVRFQHFEGPLHAPQPRGDDVKDLDAIEVVYHVTRLATVSSTVMKLKSALYLLCAPGSPLGYAAKFFYARRPVHETLCHVLHVAKPSPKKQPPVIGYAYYKDINRERQRRFTPRLHPKSDINHPVERLCRLYLRKVTPDNWSDDPYIVCLLLALAQAQSIKQREEKPETFPVRLFLVADGDKNYAHVFQADVDAHILKALDEPTLDLNGVAWPRITHTKVALQSYLTLPDRIVAELLGSYMEEKAEKRKYEDDAEAPMKRVKTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQN3</accession>
    <name>X0BQN3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_14349</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658428">
        <property type="protein sequence ID" value="EXK81197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658428">
        <property type="protein sequence ID" value="EXK81198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQN3"/>
    <dbReference type="eggNOG" id="ENOG502SA7U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089381_1_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47251">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47251:SF1">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="112"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK81198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="167" mass="18045" checksum="87C588AED7079EDC" modified="2014-05-14" version="1">MPPRHLTLPSAQTASAREAQKSFYCQLCSKGYSRMNDYEAHLSSYDHSHKQRLKDMKAMVRDPTAGSRARKAEAKADGLISIKLPGQETATGGGGFKKGGFKKSGFKSAFTKVESGGPAATTTTEKPKPASTLEPATVNPGLQKNLSPESDTEDEGYEVYDPRFPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQY2</accession>
    <name>X0BQY2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA/RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_14661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658434">
        <property type="protein sequence ID" value="EXK80889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQY2"/>
    <dbReference type="HOGENOM" id="CLU_010014_4_2_1"/>
    <dbReference type="OrthoDB" id="2017974at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005697">
        <property type="term" value="C:telomerase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000202">
        <property type="entry name" value="Unplaced genomic scaffold supercont1.7, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF0">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN EST1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA-binding" evidence="2">
        <location>
            <begin position="193"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK80889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="556" mass="64083" checksum="60178C9B46EDA31F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRF0</accession>
    <name>X0BRF0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11262</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRF0"/>
    <dbReference type="eggNOG" id="KOG1502">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_1"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="353" mass="37796" checksum="DF741AE279EF247E" modified="2014-05-14" version="1">MPSAYPKPILPPSLIAVTGANGFIAQHCIALLLCEGYKVLGTVRSQTKVEQVLELHGRDPNLSVRVVENITSVESYISAFGSIRPDAILHLAAPFHYDTTDLEKDLMIPAVKGSTAILNAANQLGGVKRIVHTNSFAGIYDASKGLQPGKIYTAKDWSPLTYEDGVNAPAAAVAYRASKTVAEKVAWKWMEENPAAHFDLVSLNPAMVFGPFLQGAVPKSSEHLNTSNQIVYGIVSAGQDGEIPATKGPVWVSVKDVALAHLKAIQVPEASGERYLLAAGVYCNQEIADVAREVAGKNKDKIPTGTPGLTEASTHFGVDASATEKALGIKWQSLDDMLSGLLPQLFEIQKRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRI2</accession>
    <name>X0BRI2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRI2"/>
    <dbReference type="HOGENOM" id="CLU_099504_0_0_1"/>
    <dbReference type="OrthoDB" id="5089608at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="244" mass="26440" checksum="0DE606D4BDB069CA" modified="2014-05-14" version="1">MPCAIASVDDDVSPIHSSYEIDLVLSLAPGTPIKLYRVTLRALQEEVPTEGPDPWADAIIDRGSDRGSSPMSDGEDLIDSVTRSFTIWSGSVSCASGRTTLSNSSWSQAQATIHGNATSVTSGANVKVSCFGDIKGRDDSYMLPHTQALNMSPIKIENRSNGEILDVCFEIEDTEDETEAIDPRITAVLQTDNDTSDPIPARQLNFELVIWTMPERFISLGGTEPVKIVRTFKVLRPPQAGTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRI9</accession>
    <name>X0BRI9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_11035</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRI9"/>
    <dbReference type="eggNOG" id="KOG2615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_54_5_1"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF2">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="476"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="508"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="18"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK84790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="561" mass="60898" checksum="9EEAABB15CFDB880" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0BSZ4</accession>
    <name>X0BSZ4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beige protein homolog 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_10652</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May be involved in protein sorting and cell wall formation.</text>
    </comment>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26681at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06071">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01201">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1540.10:FF:000001">
        <property type="entry name" value="neurobeachin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1540.10">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056252">
        <property type="entry name" value="Alfy-like_Arm-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000409">
        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051944">
        <property type="entry name" value="BEACH_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031570">
        <property type="entry name" value="NBEA/BDCP_DUF4704"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023362">
        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46108">
        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46108:SF4">
        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23295">
        <property type="entry name" value="Arm_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15787">
        <property type="entry name" value="DUF4704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14844">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01026">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81837">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50197">
        <property type="entry name" value="BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51783">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BEACH-type PH" evidence="8">
        <location>
            <begin position="1813"/>
            <end position="1944"/>
        </location>
    </feature>
    <feature type="domain" description="BEACH" evidence="7">
        <location>
            <begin position="1983"/>
            <end position="2275"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="2424"/>
            <end position="2465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="918"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1253"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1732"/>
            <end position="1808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1260"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1732"/>
            <end position="1741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1742"/>
            <end position="1762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1781"/>
            <end position="1801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00054699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00073334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK85280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="2611" mass="293398" checksum="3FDE542655F34BE8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2024-11-27" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTU7</accession>
    <name>X0BTU7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucose 1-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10669</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTU7"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF63">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="279" mass="29882" checksum="3B52D06CCEA212BA" modified="2014-05-14" version="1">MGRLAGKNAVITGAGGGIGLETSILFAKEGASILMSDISQPALEKAAAKVKQLVPDAPRVEILKVDVSKESEVQAMIESLDSWGGIDVLFNNAGIMHAQDDDAVNTPENIWDLTQNINVKGVWFGCKHAVLSLRRNKKTKASIINTASVVALVGAATPQLAYTASKGAVLALTRELAMVHAREGFRFNNLCPAPLNTPLLQDWLGDDKEKRHRREVHFPMGRFGEAVEQAQAVLFLASDESSFVNGHDFAVDGGMTKCYVTAEGPAHPPPQNNASKDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW87</accession>
    <name>X0BW87_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome P450 7B1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979329">
        <property type="protein sequence ID" value="EXK82764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW87"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018012_4_2_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053007">
        <property type="entry name" value="CYP450_monoxygenase_sec-met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="56737" checksum="00918D3B02D22698" modified="2014-05-14" version="1">MFREIVYGVAGFVLLAYAAEWILSLFDDPREPKRLQSKIPLFGHLWGMMKYSSGYHGITSKQTNEEMYTVAIFNTKLYIAKTSRLIPLIQKTSKTLSFRPFMQTAAKLMGDAKPETFEVFGTEWVDSFSHAHKNGLATGPFLDEQNLRMGDRALIDIEQLLPVEKDGVAKVNLLDWAQYAVVQASACGIFGVEHPFLDPKVDQAFWKWQSYLPLHMVNLDITGKGYAARQIVFDAFRKYNKNLPSDVSFIYKERLRSMEEAGIDEDDICKQQATFGTAAFANTVPIMYWTIYELFSRPDLLEEVRKEVIERAVSGDKESGFKVDVAALKTKCPLTLSVFQETQRLRHVHANIRKVTEDTLLDGKYLLKAGHYVMMPGQPVHTNTSTWGPTAGQFDPYRFTKDSSDRKASSFVAWGAPPHLCPARQFATTEILIVIALLAVRSDIAPVKGEWLKNPALNTGDMATVYTPKKSVEVEVRKRDDWDGEWSLRMGESKTRISLASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BY57</accession>
    <name>X0BY57_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658399">
        <property type="protein sequence ID" value="EXK83838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BY57"/>
    <dbReference type="eggNOG" id="ENOG502SXTM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_24_0_1"/>
    <dbReference type="OrthoDB" id="4072826at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="57"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="264" mass="29940" checksum="CCA3F26D8C849F95" modified="2014-05-14" version="1">METMAPLHHALPPLEVFFNAEDFQNLGMTPWFSYSVTLPERPIPSASDRPPLETERLIIRPLSMKDLDAFHELRKRPDIQNHSTARGRATKDKDETERQLHSLVQDDQSHWWFGAFLKSTNELIGEGGLPDVLAMSSSISGWPEAEFLIKPEFCRQGYGTELWKAVMDSWWDLPRERRRHQLVPVVAPGKEPGDKMDECVVFQWEAGNEAAKNFFAKVLSQAPVAAQGGCESIDTRDGKEGNLIRWAGTIICNPRPMPEEEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYD5</accession>
    <name>X0BYD5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_12229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYD5"/>
    <dbReference type="eggNOG" id="ENOG502S43F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096872_3_0_1"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020915">
        <property type="entry name" value="UPF0311"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315:SF1">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11578">
        <property type="entry name" value="DUF3237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK83534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="191" mass="20974" checksum="9DA2073118593EED" modified="2014-05-14" version="1">MSSHVPSPGNDFSPSEADIPTMRMPHLEFIYRIVAEMDKEGVTEIAGIDGTSKSRVVLPIQGGQVNGPQIKGIIVDKSGADWAEVINPNKSLVRLNAMYTLRTHDNVHILVKAQGIYRTGPGVEEQVGERDTVTQDEMEYFTHIKFEAPGDSSYGWLNSVVAIGAMIMSEGRPVIDCYRLTNFPGKRAANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BYY5</accession>
    <name>X0BYY5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BYY5"/>
    <dbReference type="eggNOG" id="ENOG502S3GI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066049_0_0_1"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="261" mass="29661" checksum="E1C91439602159F7" modified="2014-05-14" version="1">MDTNPEIVQPADWQTGEAVPAFLIHDGGGTTFSYHCLEPLRRPVYGIYNPKFHSGEPFDGGLSDMARLYTGWIKETVEKPDFPRRRNAAGKIRLLLGGWSMGGHLSLEIAKQLEDSNIEVIGILMVDTIYPHKFSSEKRKMPGEDSKEGKNKNQILADLAMADARRMIQAWTPPAWEVGRRPRVSLLRAKKAVPTENGTDIVDLSREERNLGWDMYDKNFFADVVDIEGHHYEVFKFEFIEDISKKIKKALDDLEWVALDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZI3</accession>
    <name>X0BZI3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZI3"/>
    <dbReference type="eggNOG" id="ENOG502S7Q5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_700295_0_0_1"/>
    <dbReference type="OrthoDB" id="3350591at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022085">
        <property type="entry name" value="OpdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053204">
        <property type="entry name" value="Oxopyrrolidines_Biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12311">
        <property type="entry name" value="DUF3632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="395" mass="45762" checksum="9D7224F9C0F2E6EE" modified="2014-05-14" version="1">MPKTRPSKEKRDQAKAEETRIRRIERETKENDRAETVADDDALNLAAKIDRLAEIRNWFCAETTVVDQYMAGDLSRTETVDILATPIDEAYSTANAGTAYFRQERTARLQRKYHSPEKALELWGPEQDWPEPENERDHSENAEMLLWNLWYSILHTAKKIRFTDEARQEKLVDLVRALKARPDPPEPVPMTIPLKRDWVWQLGTVWSDLIILGASIAEVRNDSCGCGAGWSWPEQQAEQNLNAFYARLTASGVANIHVQGEICAVDALEKAPTPWYRRVSPPPDHEILSHYITCAALWTIIAGKEVYAKYPHTRDERDIEVVDRILELRDNELPWNRSRKKYKGRARWETARREFARRRFEAESNNEDLSPEVRDLAGRAAKAMSDIVWQKQEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZY8</accession>
    <name>X0BZY8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">dTDP-glucose 4,6-dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979601">
        <property type="protein sequence ID" value="EXK76107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZY8"/>
    <dbReference type="HOGENOM" id="CLU_007383_1_14_1"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000304">
        <property type="entry name" value="UDP-glucose 4,6-dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="34"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="193"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="305" mass="34190" checksum="27C8FED045884D08" modified="2014-05-14" version="1">MRYNFLQDADIWQDAPILTGSTKFEPHPDVKNIMVTGGAGFIASWLVRHLTLTYPDAYNIVSFDKLDYCASLNNTRALNEKRNFSFYQGDITNPVEVVDCLERYNIDTIFHFAAQSHVDLSFGNSYSFTHTNVYGTHVLLESSRKVGIKRLIHVSTDEVYGAVNDDDDDLLEASILAPTNPYAASKAAAEMLFPEKIIPKFSLLLHRGQPVVLHGGGSPTRRYLFAGDAADAFDTILHKGEMGQIYNVGSCDEISNITLCLKLLAEIGIDDQNTAEFKKWVKYTHDRPFNDHRYAVDATKLKQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C080</accession>
    <name>X0C080_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Repetitive proline-rich cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_11658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C080"/>
    <dbReference type="HOGENOM" id="CLU_044871_0_0_1"/>
    <dbReference type="OrthoDB" id="3561626at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738215" description="Repetitive proline-rich cell wall protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK84159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="58552" checksum="4347D5388C64E171" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0H0</accession>
    <name>X0C0H0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0H0"/>
    <dbReference type="eggNOG" id="ENOG502SIVD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119621_0_0_1"/>
    <dbReference type="OrthoDB" id="3899536at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936102" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="21722" checksum="938999FADD3C54FA" modified="2014-05-14" version="1">MHFTTAALSALLASAVSAVPLNSTPYDNPDSNIFPSFHRYSDWAICKGKITKDRFPNLQAHNREGGCVRYYQGIDMTGVVTEQHFFFKDGFKTACDCAAKCLEEPNKCTNWVWKHTFMPEDGGKRSCTLYSSPNLPTDVTLKYDLANSKGFNLLQATNNPQAGAPAPLTFLDAAGTIPDKFGVSGFMVQDQNGRQFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0X9</accession>
    <name>X0C0X9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_11460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658396">
        <property type="protein sequence ID" value="EXK84424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0X9"/>
    <dbReference type="eggNOG" id="ENOG502SI0U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020030_3_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF51">
        <property type="entry name" value="ACRIFLAVINE SENSITIVITY CONTROL PROTEIN ACR-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="71"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK84424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="543" mass="59855" checksum="273B98F082B45084" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0C120</accession>
    <name>X0C120_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C120"/>
    <dbReference type="HOGENOM" id="CLU_930929_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936705" evidence="1">
        <location>
            <begin position="20"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="303" mass="31584" checksum="521C5E4E132F1A40" modified="2014-05-14" version="1">MYFSNFLVTLASMASMASAIPAPDALLDTTSNISPSDFTIRSDSNNLEARTTFSCPGAMSYCPWTKACSCPPGQSWDGKAKKCAGKKASGCWPKPSASVYAGAGVDVKLGTYCAASPYKIVKYDTKHAYCQASLKNTVFLAPLSIGAEVALYGGAAINVKGQLSASLKTVCGGLAGLYLESSADAVALFNTNKYGYAVRPGSVTGGLVYAVVDFVKSITCFLGLGNCQVYDCVSYCSKGCKNYVDVRGSIGGYVNGLVGFCIVKDTVLFVNKVGACASVKIQGLIRIVASIHVSLKGIFGCNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1C3</accession>
    <name>X0C1C3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK84988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1C3"/>
    <dbReference type="HOGENOM" id="CLU_099926_0_0_1"/>
    <dbReference type="OrthoDB" id="5142879at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="253" mass="27697" checksum="78A9614276A65DEE" modified="2014-05-14" version="1">MCVLCKRFSYSVASVTMHLLSGVGGSCESTERLNNVPRRDSSISLEESAYKQDNPEPTRTPLVPLESQKIEGCHDPNPGHGCTLPIPSPSSSPSVVAPIDVYLQFGESLEARLIRLGAILSQGRQTSEPENISLSPEASSWDVVNTPQTLDRKVPSTPVLQPTQCPKATNLQPTTTGPDIEDVDRMSVDSKYVSDLLLSDASHAASDSADSHKEAIIQYQNAPKRARREDRARIHKNLKKRTNKKKKVKSKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1V9</accession>
    <name>X0C1V9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1V9"/>
    <dbReference type="HOGENOM" id="CLU_2026827_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="122" mass="14019" checksum="43CFBBF42B1F800B" modified="2014-05-14" version="1">MPIEPSLPLSEMLGSKKRCLPWFSFHQVNIGDGSFLGLFFLSGVIIQRPNQKLHVTLPYAILELSLRVSTKRASFLQPRANPLFTRPSKPWHVSANALSMTFHCNRIWMNKKDYCRVMLLCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2W6</accession>
    <name>X0C2W6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2W6"/>
    <dbReference type="HOGENOM" id="CLU_3050370_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="54" mass="5966" checksum="A4031410F7CE59A2" modified="2014-05-14" version="1">MAVFTSLVDAATSSVTYAGDNGRPVTVLSGMSVASWREQENLLLHEQEHEHQHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C2X1</accession>
    <name>X0C2X1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_10590</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFB7 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C2X1"/>
    <dbReference type="HOGENOM" id="CLU_154847_2_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008698">
        <property type="entry name" value="NDUB7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900">
        <property type="entry name" value="NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05676">
        <property type="entry name" value="NDUF_B7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="13" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK85518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="86" mass="10138" checksum="4470DA2592C11FA6" modified="2014-05-14" version="1">MASDAITEPRQATREEMRDAKLPLAYRDSCAHLLIPLNKCRRDTWYAPWKCSDERHSYEKCQYVEFKKRVAKMDELRESKGGARSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>X0C327</accession>
    <name>X0C327_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_08100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C327"/>
    <dbReference type="eggNOG" id="ENOG502SZAF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026865_0_0_1"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="87"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="118"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK88810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="717" mass="81047" checksum="035EAAA8C3D3DE18" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3H5</accession>
    <name>X0C3H5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3H5"/>
    <dbReference type="eggNOG" id="ENOG502SHS9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_8_6_1"/>
    <dbReference type="OrthoDB" id="3358371at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05251">
        <property type="entry name" value="NmrA_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF26">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="3"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="331" mass="36331" checksum="985C8FA821BAA859" modified="2014-05-14" version="1">MSSKLIVILGATGNQGGSVAEAFLSEPGWKVRALTRNTSSAKAKALSSKGAEVVQADLDDPSSLNSAFGGAHAIFAVSDFWGLYYNESNRSKTKPGQALNDWAAQHEEQQLKNVIDIAAKVPTLERFILSSLSHSEKWSKGKYIRVYHFDGKARATEYAQKEHPDLWAKTSVYQAGLFLSNFVLLPPNQPFKDADGVAQFVSTLEVDTKFPYIAPEEDTGPFVKALIIDEPAGHNLIAYREWLSANDIAAAFTKATGIPSKAIKDDGAIPPGISDELLGEMIDCFSYFNEFGYEGRDDPTVVHPRDLKFAPKLSTAEEYLKKQDWTKVFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3W5</accession>
    <name>X0C3W5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAGA-associated factor 29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658389">
        <property type="protein sequence ID" value="EXK85489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3W5"/>
    <dbReference type="eggNOG" id="KOG3038">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023535_1_1_1"/>
    <dbReference type="OrthoDB" id="10265994at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20393">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037802">
        <property type="entry name" value="SGF29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010750">
        <property type="entry name" value="SGF29_tudor-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047288">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539:SF0">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07039">
        <property type="entry name" value="SGF29_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51518">
        <property type="entry name" value="SGF29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGF29 C-terminal" evidence="2">
        <location>
            <begin position="318"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="454" mass="50413" checksum="56B0F13CC29D2DAB" modified="2014-05-14" version="1">MANGQKPARDELKNLQEDLGPYYQIPLKPRRSGTHSRENSFQESLRQSSNTPEPKRSGSKRQDPSSRDSTPNRPTKSRTKNHSRDITSDVGTPKRSPRSEHNTPRPESVKPERHNREMSQRNRSGRASNRNNGNSHGEEVQIWELCKSQVGEIVSGINAENDSLTELVTMDKQVGTMDLEKIPSDSLKEMEQLCRTGVKHSEANMSALKNTIEQLKVLRAVVHAKEQQDAQAAGPGKRNARDSAAAASSLYDFDGAGDSPVPSPIGGSARKYGDRARERERERERERERDRDSMPPKADSVEPQGSVGSGVGSGNNKSKVVFSKGDAVAFKPKALNGDTTSDWILGEVAQVMGEGKSRRYKVLDIEPEDQSKQKEYRSSASSMIPITPESQASTLKDWESGKVVLALYPNTTTFYKAEVHSMDSDGKVNLKFEGENDSSTLQQVERRFVIEYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4V6</accession>
    <name>X0C4V6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_07551</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4V6"/>
    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF78">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="469"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="536"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="76"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="567"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="582"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK89450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="595" mass="64212" checksum="3959FD2060C50AA3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-09-13" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5C3</accession>
    <name>X0C5C3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5C3"/>
    <dbReference type="HOGENOM" id="CLU_2263888_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936180" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="12263" checksum="3A198D4329B1D858" modified="2014-05-14" version="1">MHTLYGTFLHVLFCLLLSELTQSPTTQLPAAVRSLFGARNAGQTQKYQKAGVRCICQCHQPPIYTGLSGFIPHARALRDKASDTIEIKLFRRTVWHQGYFHNNQYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0C5I5</accession>
    <name>X0C5I5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_07511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C5I5"/>
    <dbReference type="HOGENOM" id="CLU_1875493_0_0_1"/>
    <dbReference type="OrthoDB" id="5082877at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK89406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="136" mass="15353" checksum="5DD0E35EE77E517C" modified="2014-05-14" version="1">MSFGHQDNPPNPFSGADVQQHGFNGKHRDWSINQYERPDEKKPGNAKDLELQSCERKESAGNDQDSQSQPRNDQNKTAKTNKCNCRHQQAATEPSRPEEKTESRKTEGESEDDTVGTEGLSIRLGLCCMFFELDHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6V2</accession>
    <name>X0C6V2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_09291</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK86924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6V2"/>
    <dbReference type="eggNOG" id="ENOG502T0QC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1069774_0_0_1"/>
    <dbReference type="OrthoDB" id="5101370at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007738209" evidence="3">
        <location>
            <begin position="19"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK86923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="246" mass="26334" checksum="F882D4B1CC578A97" modified="2014-05-14" version="1">MYSKSLVVPALFAAFGIAQEDVQYETRTATITQCFTRDGLRPPATVTVPGPTCVVHKPAVTGEAIIVEVQAPDCHCGCPTCVHTLEYTTKYPAFCSTGIFEQEYIITETYSGMEAKPTKNEHDLPYGFTCDVQTCTTCGPEPVTATITYPVSDRPYMNEVAPTEMPMAKPGKEQPEEQGNAAPKVTGDNNGFQSSVKPSVVPESPESAPPGESTDRPVIVSGAMSQHLGLAGAGIAFFALIQFLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C893</accession>
    <name>X0C893_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C893"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_285454_0_0_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="194"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1084" mass="121749" checksum="2EB30AEC638A63EC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C898</accession>
    <name>X0C898_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alpha-N-arabinofuranosidase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09229</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C898"/>
    <dbReference type="eggNOG" id="ENOG502R8XS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009397_2_0_1"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18820">
        <property type="entry name" value="GH43_LbAraf43-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817:SF1">
        <property type="entry name" value="HYDROLASE, FAMILY 43, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939199" description="Alpha-N-arabinofuranosidase 2" evidence="6">
        <location>
            <begin position="21"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK87428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="36826" checksum="5E939F1690D12EE9" modified="2014-05-14" version="1">MLVLSVITLVLGLCSSFVLGFTNPIRTGSDPHIVYQDGMYYLTSTTWTNVSITKAPTIEGLKTAESQLIWSDRSNATRACNFWAPEMHKVGDTWYVYFSASVCDEGNWDVMLPTLRVYVLKGGKENPLSADYEMMDAIIPPNFNAGMLDATIFEIEGTEYFLFSSVEGPKSPDGASLWIAKLLSPTTCGNATMIAHPEFEWEKSDSPVLEGPYGIISPAGTTYVVYAADSCNTPAYKLGAMIFTKGSDPLSPDSWTKLPDPIFETKNGLYGPAHNAFFKSPDGTEDWNVFHANLNAGDRCGPSRKTFIQPLSWKDDMIDLGEPHPVGAEIKPPSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0C8Q7</accession>
    <name>X0C8Q7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_08931</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C8Q7"/>
    <dbReference type="eggNOG" id="KOG4231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_144_2_1"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07216">
        <property type="entry name" value="Pat17_PNPLA8_PNPLA9_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="16"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="4">
        <location>
            <begin position="20"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="60"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="4">
        <location>
            <begin position="234"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK87593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="375" mass="42032" checksum="7EDDEA39B7AD958E" modified="2014-05-14" version="1">MVYVTSTKHPKGLRLLSLDGGGVRGIMGLVILRELMLRVQKKKGLDKIPLPADYFELAGGTSTGGIMGIMLFRLRMSVDDTIKEYDRIAKTIFSPKIYGWDISWIPGSSYLNNSKALVQDSRFDAGSMSKAIDEVVEKFGLDENDKKLKGNAPLQHEGGARMFCCTTAQNRAESMLMRTYKDKTIYTKSKVNDALLKHGDKLTISIAARATSAAPTFFPEVKFPEDKPELVFWDGGLLNNNPIDQLWYTRFELVDPKDPSPPISCVISLGTGYVSPGKAKQSWIKVVGVASKVMDFATNTNAKGKDFSRHMTHLNERDEHKDTKYIRFNPFLKEEIGLDEYLRMDDLKVIAQKTMDDPNPTNQFWINQAVDAICA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0C978</accession>
    <name>X0C978_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658476">
        <property type="protein sequence ID" value="EXK79227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C978"/>
    <dbReference type="HOGENOM" id="CLU_1815893_0_0_1"/>
    <dbReference type="OrthoDB" id="10338851at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="142" mass="16226" checksum="148149D7FDC19B1F" modified="2014-05-14" version="1">MGTLIRESQVNKSKLISDWLLKIEKPSDDSIHKKKRHKASCKERYFNTEYPCQRIPTTSNSSHDNQLVANPTPQNLQDASKPMPRKHARSITEMVGSDEEGDAIDDTPKASSRGWRKKALDLSRAQRHLMPLLPQPRVLHHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB16</accession>
    <name>X0CB16_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase</fullName>
            <ecNumber evidence="5">3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_08246</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="5"/>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB16"/>
    <dbReference type="HOGENOM" id="CLU_017266_1_2_1"/>
    <dbReference type="OrthoDB" id="10261878at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000002">
        <property type="entry name" value="Xaa-Pro aminopeptidase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF1">
        <property type="entry name" value="XAA-PRO DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="13">
        <location>
            <begin position="82"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK88413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="531" mass="59306" checksum="68328FAA822E6514" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CBY6</accession>
    <name>X0CBY6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CBY6"/>
    <dbReference type="HOGENOM" id="CLU_2263841_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK88713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="103" mass="11820" checksum="EE55D3EA1FDF7C63" modified="2014-05-14" version="1">MSCTRRIGFAPHGERISYQEEPSQNGFIRRSYRTVDARCFRYPLPWPGAGTRPRRLTRTSKWGDTTKEFPPRPSVLAQLFLSESWDPERASLSVQDAETSCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCT7</accession>
    <name>X0CCT7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit L</fullName>
            <shortName evidence="4">eIF3l</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_06104</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit L family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCT7"/>
    <dbReference type="eggNOG" id="KOG3677">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="15082at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03011">
        <property type="entry name" value="eIF3l"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019382">
        <property type="entry name" value="eIF3l"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10255">
        <property type="entry name" value="Paf67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="257"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK92215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="476" mass="55026" checksum="681FCE3CFA124028" modified="2014-05-14" version="1">MATYQNGVAPARAIDDDSDVEEEALVAEYKEHVQYEDGDDLSRTTSLNLTAQTDDIQARLVQAAQPLDFQAPLEAKFQSYDAYCSLFHFILNSEGPVDLEPPSYYWAWDVIDEFIYQFNSFSSYRMRIARQTTNEEERQALRENPNTWGCYSVLNVLYSLIQRSQITEQLAAMKRNEDPLAVAGEYGSKNLYKMLGYFSIIGLLRVHCLLGDFSLALKTLDDIELNKKAMFARVMAAHFTTYYYVGFSYMMQHRYADAIRMFSHILIYVSRTKNFQKSAQYDSITKKNEQMYALIAICVAFQPTRLDDTIHSALREKYGDQLLKLQRGGPESLPIFEELFRAACPKFISPVPPDFENPEANIDPVEHHLAVFMDEVKTNMWSPTIKSYLRLYTTMDLNKLAGFLEVKPEELRSWLLVTKQRTKQLRWQDQGLLEGELVNVSDLDYALQGDLIHISEAKVGRKLVDWYLRNLSRTYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CCV6</accession>
    <name>X0CCV6_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucose-fructose oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_05978</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CCV6"/>
    <dbReference type="eggNOG" id="KOG2742">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_3_1_1"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF5">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="3">
        <location>
            <begin position="151"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK91996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="345" mass="37342" checksum="523E06F4A1CC110B" modified="2014-05-14" version="1">MAPIGVALIGGGLFAKQAHMPAIMKADNLALNAIYSRSLKSAKETAALNTRSGQEPDLYSADSGSGKSFDDLLAREDIEAVIIALPIPSQPEHIRAALAAGKHVLAEKPLAPTVADGQKLIEYYRGLGGKATFSIAENFRYKPSFDYAAAEASKLGKLQHFSVRVFFYMSEDSQWYGTAWRAKPEFQGGFLLDGGVHFSAATRQLLTDPAVDVTAFTTQTQPHLAPIDTVNAVIRLKSGVSGTYQQSCGSKMSTSVFQFGYEKGSVVVDGDKVTVTPWDDEPVVKEFERTSGVTEEVEAWAKALAEGKPDKRQSVEEALADLEFLELMFESGLNGGQAKKYECQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDB9</accession>
    <name>X0CDB9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDB9"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK92430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="380" mass="42481" checksum="56135B5F94EE186D" modified="2014-05-14" version="1">MGRKLPWKTSSTPSGPERKTSVKSESPLPTPSRALHPGTPSAFRKKPRRERVIEAEGIPDSTLSSKPQRNRQYHTDTTRSPSTSPPPEPPKERFMRPGLDHDDRYRIVEDEFVNMAHQFTLHIHASEYNRLKNLAKHQNADTIREIERPVVGAPTLLTRHRQEDVRRNAKQRKLLGNDANEKKDSPYVGSSLQGLMESPRKEHKWISTGLADTAATRASAGFNSQKISPLRLKQGSNSSSAKRRQISLGDDDETDDGDDLDPTTPSRTAATKAARTTHTSSPAMPRSTPRTAFSTPRTLKSAMNTTSRSGSSVKRPTTAPGGSEARKITKSRDAQEHIDDDDPFGINKRRIQRQKSREQFRKTEEKTPSKSSLDDIPSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDJ4</accession>
    <name>X0CDJ4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_14820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658438">
        <property type="protein sequence ID" value="EXK80687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDJ4"/>
    <dbReference type="HOGENOM" id="CLU_087032_0_0_1"/>
    <dbReference type="OrthoDB" id="5051934at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK80687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="213" mass="24230" checksum="717E32BC92B38267" modified="2014-05-14" version="1">MNTGVRKIASGSKDPIGLTPSEYRILAFWSNHLGSTKVPFLAEHAHTIYEARGKTRPYSKHDLEFISWTVGAMKREVATRDTIMAEICAEHGKILDLEYEMRIEGGLARLSTGREKPKGKYRSGGERMTARAHVPNPLFINDQDIDKITDPKLISSLAGTDMAISRIKVYRERLNGEKTRIDNAKTLCHKKEFADKRLNTLNEKRQYLKSQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-09-13" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDN7</accession>
    <name>X0CDN7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cystathionine beta-synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07957</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDN7"/>
    <dbReference type="eggNOG" id="ENOG502S7T3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105491_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42115">
        <property type="entry name" value="BETA-SYNTHASE (BETA-THIONASE), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42115:SF1">
        <property type="entry name" value="BETA-SYNTHASE (BETA-THIONASE), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="18681" checksum="409CE124803CE1BC" modified="2014-05-14" version="1">MATATATTTTSGATQPLVTKWSSRYRGATVEDLDPPAALSLNPSDAISLALMSAFERDYTHLTIVDADTRALLGYISIPHLQSLLDSGKVKPEDQLSAAMTRFQRKGRTYQVITMETTLEELENFFRGGVPDGPWKQEFAVITDEKRRFVLGVATVQDLEEFVKRRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEB2</accession>
    <name>X0CEB2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 2 subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_05768</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF2B.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEB2"/>
    <dbReference type="eggNOG" id="KOG2916">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033458_0_1_1"/>
    <dbReference type="OrthoDB" id="1685042at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1130:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000015">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.190:FF:000002">
        <property type="entry name" value="Translation initiation factor 2, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="entry name" value="Translation initiation factor 2, subunit 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="eIF-2-alpha, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="eIF2alpha middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="18"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="284"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK92730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="311" mass="35245" checksum="1F7D2822F2B4DE3E" modified="2014-05-14" version="1">MAQNQHCRFYEEKYPEIDSFVMVNVKQIAEMGAYVKLLEYDNIDGMILLSELSRRRIRSIQKLIRVGRNEVVVVLRVDKEKGYIDLSKRRVSPEDIVKCEERYNKSKMVHSIMVHLAEKTKLDIESLYEAIAWPLNKRYGHAIDAFKLSITNPEVWNDITFPNEVAKEELKSYIGKRLTPQPTKIRADIEVTCFGYEGIDAVKTALRTAEAHSTDDTQVKVKLVSPPLYVLTCSTLDKNVGITCLGEAIVDVRKSIEGAGGNLTVKMEPKAVTESDDAELQALMEKRERENAEVSGDESMSDSDENIPETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CEY8</accession>
    <name>X0CEY8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_14407</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658429">
        <property type="protein sequence ID" value="EXK81162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CEY8"/>
    <dbReference type="HOGENOM" id="CLU_001265_1_0_1"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF240">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="42"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK81162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="434" mass="46563" checksum="C1B57157181C48BD" modified="2014-05-14" version="1">MANLSINNHPLGELANIRPRTSNPSTRVDEDDIVYPEGGLEAWLVVIGAWFAMIPSMGLLNTLAVLQAWVLENELPHLPESTVGWIFGCYGFFLYFCGAQVGPIFDTHDIKLLIIPGSFGMVLSMVFVSFSTEFYQFLLSFGVLGGISASLLFNPSLAAIGHWFCQRRAFATGLACTAGGIGGIVFPLVILYLAPKIGFAWAIRVIALINMGAGVLACCLLRKRLPSNKKAGASIDLKALADVKFASTTAAVFLIEFAVFIPYSYISAYAMHYGFNSQKAYLLNTLLNVGAVPGRALPGYVADRFGTFNTMCITSFVCAAVILTLWLKAAGEEARTTSFTLLYGFWSGAAISLTPVCISQVSMIEDIGKRTGTAFFIASFGALTGIPIAGAILEAGNDSYVGLIVFAGILYISAFATFVLARGIAGGWRWAKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF26</accession>
    <name>X0CF26_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_07540</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658377">
        <property type="protein sequence ID" value="EXK89439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF26"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF38">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="15"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="510"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="516"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK89439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="534" mass="59297" checksum="84270EF3E9193E14" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>X0CFU4</accession>
    <name>X0CFU4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Urea amidolyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_05406</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002162_4_0_1"/>
    <dbReference type="OrthoDB" id="167809at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004847">
        <property type="term" value="F:urea carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000010">
        <property type="entry name" value="Propionyl-CoA carboxylase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053844">
        <property type="entry name" value="AH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014085">
        <property type="entry name" value="Allophanate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003778">
        <property type="entry name" value="CT_A_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003833">
        <property type="entry name" value="CT_C_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014084">
        <property type="entry name" value="Urea_COase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02713">
        <property type="entry name" value="allophanate_hyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006043">
        <property type="entry name" value="PRK08186.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00724">
        <property type="entry name" value="urea_amlyse_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02712">
        <property type="entry name" value="urea_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF128">
        <property type="entry name" value="UREA AMIDOLYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21986">
        <property type="entry name" value="AH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02626">
        <property type="entry name" value="CT_A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02682">
        <property type="entry name" value="CT_C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00796">
        <property type="entry name" value="AHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00797">
        <property type="entry name" value="AHS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160467">
        <property type="entry name" value="PH0987 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="11">
        <location>
            <begin position="642"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="761"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="9">
        <location>
            <begin position="1760"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1309"/>
            <end position="1329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK93260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1829" mass="197340" checksum="7E7780F030B702F5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CGG4</accession>
    <name>X0CGG4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_04789</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CGG4"/>
    <dbReference type="eggNOG" id="ENOG502RXWC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035821_0_0_1"/>
    <dbReference type="OrthoDB" id="2556122at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044695">
        <property type="term" value="C:Dsc E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045226">
        <property type="entry name" value="Dsc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025390">
        <property type="entry name" value="Dsc3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019413">
        <property type="entry name" value="Dsc3_ub-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049:SF1">
        <property type="entry name" value="DSC E3 UBIQUITIN LIGASE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN YOR223W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13373">
        <property type="entry name" value="Dsc3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10302">
        <property type="entry name" value="Dsc3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="DSC E3 ubiquitin ligase complex subunit 3 ubiquitin-like" evidence="3">
        <location>
            <begin position="16"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="DSC E3 ubiquitin ligase complex subunit 3 C-terminal" evidence="4">
        <location>
            <begin position="149"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK93520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="30769" checksum="962D5D66100CFAC2" modified="2014-05-14" version="1">MTSQASSSHPLPPPLHLTIRFTTSQPDLELDIPSPQTTTVLALKHLLRTRLSSKSRLRLIHQGHLLPDASALSSVLKPHPAPPRTNDDPKGKGKAVEGANVSRIYVNCSIGDELTSDELKKEEEEALKPPKEATGDGSKPTTSTRPRPRGFDRLLQSGFSPSEIATLRTQFTSIHTSRFTPDAMPSPDTLRNMEDAWIDNNAEGIPSGSNPLEDENSGMASVLEILFKAMMVGFFFPLGSLAWLMRQEGIWSKRWQIFVGFGVVFSLVIGFVMELSGDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CH85</accession>
    <name>X0CH85_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_06835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CH85"/>
    <dbReference type="eggNOG" id="ENOG502R59M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005027_4_2_1"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF22">
        <property type="entry name" value="CAPSULE ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="322"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK90628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="614" mass="71664" checksum="DEED175A5139FCE4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CH98</accession>
    <name>X0CH98_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_13627</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658418">
        <property type="protein sequence ID" value="EXK81982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CH98"/>
    <dbReference type="HOGENOM" id="CLU_026673_20_1_1"/>
    <dbReference type="OrthoDB" id="256333at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08297">
        <property type="entry name" value="CAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="10"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK81982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="342" mass="36669" checksum="89D6FB0EE9C47E34" modified="2014-05-14" version="1">MKAIQIKEFGAPYTVSEVDKPKPKPHQLLVQIKAGGFCHTDCMALDNAFCSKLPFIGSHEPAGVVVEVGSDVQGFAEGDRVGCLNFDSCCGKCPDCKTGRPIYCDNPLMKGITTDGAWAEYMAADARFTVKLPDSLEFPTAACMMCAGITVYGGIKRAKVPSGGSIGMVGIGGLGHIGTQVAKAMGYKVAAIDVKQDTLDLVASYNLKPDVCILSTDPAETSMEKITNIIKGDYPGLDATIIATDAPAAFDLAAKLTRKHGTMVLLGQPEKGIAMSYQNVIFRDINLIGSLVADTDETEELLNLVVKHKIQVNVKEWKPEDAEKMRQEYLAGRNSGKNVIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHS8</accession>
    <name>X0CHS8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Kinetochore protein SPC25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_04930</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Chromosome</location>
            <location evidence="9">Centromere</location>
            <location evidence="9">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the SPC25 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHS8"/>
    <dbReference type="eggNOG" id="KOG4657">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065188_0_0_1"/>
    <dbReference type="OrthoDB" id="4056921at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23784">
        <property type="entry name" value="RWD_Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.457.50:FF:000001">
        <property type="entry name" value="Probable kinetochore protein spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.50">
        <property type="entry name" value="Chromosome segregation protein Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045143">
        <property type="entry name" value="Spc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013255">
        <property type="entry name" value="Spc25_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14281:SF0">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14281">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC25-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08234">
        <property type="entry name" value="Spindle_Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="8 9" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromosome segregation protein Spc25 C-terminal" evidence="11">
        <location>
            <begin position="181"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="57"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK93711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="257" mass="30042" checksum="F0CE54EDF8C9899E" modified="2014-05-14" version="1">MATDFQSSLSASMRQSMAPVGPSVANQLPNINFGFDDLRDRMAKFTARFDAFIEEGRKRVLEERNQFRMNVAELQEDQRMKKRDIEIIQVKTSTHQQTIEKEEAETREMESAINSLAAQRDNHLATRDSLKAEIAQTQAEIEARLAAQREYAQQQQAQSRFNVPELDFWITNLCLKIEGAGHDDRLKFVYTHIDEKDWEREAWFELVTSSRDYDVKHCRPKIEREKVEKVLDKLNESRELVVLLKGMRELFVEAMKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIE0</accession>
    <name>X0CIE0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_13365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658415">
        <property type="protein sequence ID" value="EXK82342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIE0"/>
    <dbReference type="eggNOG" id="KOG4178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_16_1_1"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937682" description="AB hydrolase-1 domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="70"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK82342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="342" mass="38049" checksum="0D95C6C18D66C7E3" modified="2014-05-14" version="1">MIICLFFILATFIVQALSLQPPDYSLGKEHSSEHLNRRTGRLSRLEPLSYVNTTRLQVAYYEDGSPDAQVVLLLHGWPYDIHSYTEVAPALVKQGYRVIVPYLRGNGPTTFLHTDTFRSGQQAALGYDIIELLDALSIKKAIFAGYDWGGRGACVAAALWPERCAGLVSVNSYLIQDLSKAWVPLDAKIEAGFWYFYYFLTPRGQAALAEHPKDIARVVWNKNSPQWNYTEADLDRAAETFVNPDYVSVVTHVYRHRLLYAPGDPGYNNIEKALLEQPVISVPTVTLDGLADGNFPPTNGSSSAKYFSGPRVHHQVPGAGHNLPQEKPEAFIKAVLDVLSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIL0</accession>
    <name>X0CIL0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_04238</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIL0"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF66">
        <property type="entry name" value="MFS HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="482"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="50"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK94026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="556" mass="62474" checksum="6A539D1CEA423D62" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0CIZ2</accession>
    <name>X0CIZ2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Macro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_13117</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH658412">
        <property type="protein sequence ID" value="EXK82547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CIZ2"/>
    <dbReference type="eggNOG" id="KOG2633">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029822_0_0_1"/>
    <dbReference type="OrthoDB" id="6077599at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106:SF121">
        <property type="entry name" value="ADP-RIBOSE 1''-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106">
        <property type="entry name" value="GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Macro" evidence="7">
        <location>
            <begin position="99"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK82547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="597" mass="65910" checksum="137EAB41358023C9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLC3</accession>
    <name>X0CLC3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L28e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_06050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLC3"/>
    <dbReference type="eggNOG" id="KOG3412">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106801_0_0_1"/>
    <dbReference type="OrthoDB" id="338850at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.110:FF:000002">
        <property type="entry name" value="60S ribosomal protein L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002672">
        <property type="entry name" value="Ribosomal_eL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10544">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="5">
        <location>
            <begin position="14"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="125"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK92113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="159" mass="17090" checksum="F0D247ED1743658C" modified="2014-05-14" version="1">MSTAQELSNISSDLIWEIVRDNNCFSAKSKKNGGVQFSRDPLNLTNKTSRKHAGFVNDKALGISSGEKGAIVVTSKKAQPNKPAQNLVKTSYSGSKSNRKTYQAVANQAAKNGYRADLRSAAVERASALKKSNKPVKPEPEQKLRGTKAKKAAAAAEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLN8</accession>
    <name>X0CLN8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLN8"/>
    <dbReference type="eggNOG" id="ENOG502RYNQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031758_1_0_1"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016814">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052349">
        <property type="entry name" value="Metallo-hydrolase_Enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027:SF0">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="41"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="454" mass="50798" checksum="F1EE67C885D9E484" modified="2014-05-14" version="1">MVLKNIILPFQDSSKQWDIQIEEGVVTSMKPSAGRTTPSVMLPSLCHPHIHLDKPYLLTCNHPKSSKHPDYSDLAPKTGGFQEALVNTAEAKKRYTEEDLYLRGSQLIATSYKQGVTFMRAFVEVDSVTELKTLEVGIRLKKEFEDFLEVQICAFAQDPIFSTEKGEANRAMFMKALDQLGSKIDVIGTTPYVESDVEAQNKNIRWAIETALKHRKHLDFHIEFNLNGDGTHMSVFNHTIEELRALKWPTYPGAPTVVFGHATRLTRATHDDLVRLSETLRETKLPVHFVGLPTSDLYMMGRHGADGSEHGEPLSRPCGTIMVPKLIHDYGINACLSVNNVGNPFTPHGDGDPLKIASWGVGLFHAGTVEDAKILYEAISTRAMDALNPRAEGHHDMFTLAEFHQTMPMLLFKNEENIEISSASGSMTVLARQRLSIQDIVWDPPETRLRSIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CM07</accession>
    <name>X0CM07_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_05875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CM07"/>
    <dbReference type="eggNOG" id="ENOG502RJ3D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049345_0_0_1"/>
    <dbReference type="OrthoDB" id="5090029at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK91859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="419" mass="47628" checksum="F0559FFE50086648" modified="2014-05-14" version="1">MSSFPFGDLPTETKKNVILNALPSVTTPHRYYLSNIARIHEYVEEQTLKKIQDSDPVIASLSNQVRCLKAINPQDGTAIMSSVGGVEFRLDPKHDTFKAMEMRLPAVHPSASWNPQEVKGYHKYALPFENVLNVAYRTYLARGQAPPPGDGLTIAGPSTAPAVKVPPTYYNIPFEKDLPIFARLPKAKNLSLIVEYAGREWHINGFQMNGPDVVGRRYLLNRWGLLRSGDHSYVAEEYFRSRRIPADTGIAWNLPGRDRVSDPEDLEGVPVPISRYGIPNIGFNAYSRGNISLGGNWAGFRFWVDNNKIEFSPLCWQEVEPLIGEYYGLDERGYNTFTPGLVARVWVIRSEQDLEPTERPHHHWIEVREPQFGDPEWVEQIAATWKMTRQMLSHVRGSAIEEDEERNVAADNYCFQMEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0CNJ3</accession>
    <name>X0CNJ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Replication factor C subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CNJ3"/>
    <dbReference type="eggNOG" id="KOG2035">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042324_5_0_1"/>
    <dbReference type="OrthoDB" id="761538at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031389">
        <property type="term" value="C:Rad17 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000030">
        <property type="entry name" value="replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000002">
        <property type="entry name" value="Replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000136">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF1">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13177">
        <property type="entry name" value="DNA_pol3_delta2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22534">
        <property type="entry name" value="RFC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00070185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="352" mass="39731" checksum="F721D2EAC6E3E922" modified="2014-05-14" version="1">MALIVDKHRPRSLETLTYHNELSDRLRSLAQSGDFPHLLVYGPSGAGKKTRIVATLKELYGPGVEKIKIDARVFQTTSNRKLEFNIVASVYHLEITPSDVGNYDRVVVQDLLKEVAQTQQVDQSAKQKFKVVVINEADHLTRDAQAALRRTMEKYSPNLRLILLANSTANIIAPIRSRTLLVRVAAPTHEEICDVLAVSAKKEGWPVVEGLHKRIAEESGRNLRRALLMYEAVHAQNEKVTDSTVIPPADWEALIGQIAKEILEEHSPARILQVRSKLYDLLTHCIPPTTILKTLAFKLIALIDDGLKGEVIQWAAFYEHRIKTGTKVIFHLEAFVAKFMRIVEMYLMSMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CPU8</accession>
    <name>X0CPU8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rho coiled-coil associated kinase alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_03496</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CPU8"/>
    <dbReference type="eggNOG" id="ENOG502S7ZB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005779_0_0_1"/>
    <dbReference type="OrthoDB" id="76453at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051756">
        <property type="entry name" value="Centrosomal_MT-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024957">
        <property type="entry name" value="Cep57_MT-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025925">
        <property type="entry name" value="PPC89_CLD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19336:SF9">
        <property type="entry name" value="SPINDLE POLE BODY PROTEIN PPC89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19336">
        <property type="entry name" value="UNCHARACTERIZED DUF1167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14197">
        <property type="entry name" value="Cep57_CLD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06657">
        <property type="entry name" value="Cep57_MT_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC89 centrosome localisation" evidence="7">
        <location>
            <begin position="387"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="PPC89 centrosome localisation" evidence="7">
        <location>
            <begin position="573"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Cep57 centrosome microtubule-binding" evidence="6">
        <location>
            <begin position="935"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="91"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="484"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="681"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="336"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="494"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="706"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="792"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="821"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="840"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK96480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1056" mass="119323" checksum="35832EBA124A8BB4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRV3</accession>
    <name>X0CRV3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alcohol acetyltransferase FCK4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_10863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRV3"/>
    <dbReference type="eggNOG" id="ENOG502RC91">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024469_0_1_1"/>
    <dbReference type="OrthoDB" id="2150604at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010828">
        <property type="entry name" value="Atf2/Sli1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07247">
        <property type="entry name" value="AATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK85212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="55866" checksum="57FE5C9FA52BBBBC" modified="2014-05-14" version="1">MSSSPKPKSYIRRLGQIELCESALHSLDYYCSTVLTCRYTLPPSLHSFDNQGRVFRRFDQAIARTVLQFPLLQVGLVGESTKKPAWVSLPSLDLADHVSWDVRPDSRDYERALEANLEYQLDSKFENLEARPGWRICLMRTKTDNFVDVMYIWNHANHDGMGAKIFQQTLLQSLNNPVASSLLRSGSRVMTTSIRKDSFPQPQEKLAKHNLSLGYACSEIWNGLCPSCFHSAESKARWAPIRPDPYITRFKAIDIDAITLKKLLSQCRENDTTLTGLIHGIILACLSVDINEGNTDAFQVATAMDHRKFLRKELRPSKYASLDLDNSIQNCTASLSHLFDHEIVSDIRAQARINNWPAQPIGDLEPMIWKAAQQIRRDIEKRLDTGVNDNVVGLMKVVSDWHDYLKSLEKKPRDLSWEVTNLGVIDGETEDGFAVGRAGFTLSGNVVGPAIQISMVSVKGGELSIELSWQDLPEIHDVAKRLVQDLRVWLLYLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CS46</accession>
    <name>X0CS46_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CS46"/>
    <dbReference type="eggNOG" id="ENOG502T5G5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_997624_0_0_1"/>
    <dbReference type="OrthoDB" id="5094741at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="36308" checksum="91F5FE4A43E6220F" modified="2014-05-14" version="1">MSLQLGFIIRVNCPYLDGRPGTLPVIWSLTLSRSFHSTSPYLPHHLLSATQSMNSATLFFVIIILFIISIFFINCTITVIIRTRSRHTKSKPSSPPIMSQPIKPDTPSPNVPPPPPPNPDTPTSSTFTGATFGIRPDHVAWKCHRGFFCNIINPLTDARCATCKQERAFPADALNASHKQIGWLQSVDVHGNEKWVYFDRETLDQLRQGTLPKNFLNSSPPVSWKSGGIDGINPENSRPVSEGSGDVIGIHHGNSPPVSSETGEVGGNSREGKRMSTGVGFEVSRMERWVANVVKKQVDDEDLEEPDKQPEDEGDAKGSAAGDGSGSKRKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSU5</accession>
    <name>X0CSU5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_05096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSU5"/>
    <dbReference type="HOGENOM" id="CLU_083940_0_0_1"/>
    <dbReference type="OrthoDB" id="5232052at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="47"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK93944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="245" mass="28374" checksum="38BB63C6870DFBC1" modified="2014-05-14" version="1">MLLIPRQHAGPVGRAFEPELNRPSYSHQKFASSCPTWLPKVLQTTKLSPLERLPNDVQRLIFSNLDYQSLIFLSMVNRHFHRTVDPQRMATLRDKFELVMRAAKDFPQHWASEKKKDQRPGNLECYWCFRVRSPQHFDVLQANTAYFDPQGRLVSEQEAGPQDRLVPLRRFCIGCGVKAGLHAPSDCIVTRTGQDLWVCRCRRVWQKPNCLQCPDCSSSCPLRPKKRWCGCDYSSARPQHCVLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CT98</accession>
    <name>X0CT98_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_04589</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CT98"/>
    <dbReference type="eggNOG" id="KOG1607">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028277_2_2_1"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="9">
        <location>
            <begin position="199"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="37"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="451"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK94553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="520" mass="59814" checksum="2F415FFE6ADCFE7A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CUB5</accession>
    <name>X0CUB5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SURP motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_01078</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CUB5"/>
    <dbReference type="eggNOG" id="KOG0007">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013259_3_1_1"/>
    <dbReference type="OrthoDB" id="447637at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000015">
        <property type="entry name" value="Splicing factor 3A subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000001">
        <property type="entry name" value="Splicing factor 3a, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045146">
        <property type="entry name" value="SF3A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022030">
        <property type="entry name" value="SF3A1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316">
        <property type="entry name" value="SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316:SF1">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12230">
        <property type="entry name" value="PRP21_like_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00648">
        <property type="entry name" value="SWAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SURP motif" evidence="9">
        <location>
            <begin position="34"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="SURP motif" evidence="9">
        <location>
            <begin position="131"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="307"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="201"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK98045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="534" mass="59914" checksum="B7ED0FF1DE8BCCDF" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0CW10</accession>
    <name>X0CW10_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">N-alkane-inducible cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_01279</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CW10"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_27_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF17">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0349">Heme</keyword>
    <keyword evidence="8 11 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK98341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="57552" checksum="D3BD6077C01C30FD" modified="2014-05-14" version="1">MFSLLLIKFLEQHLLATIVLLFLPVPLRILKTYLRRWRLAQAQGCKEATSKVAVKDPVIGFDFLYKVFFEKSPERYLDSTWQAFKEMGTTYIEKRWSWQCVYTCDPRNIKQILATAYHDFDLPEFRTSVIGHIFGQGIFVLSGHPWKHARALLRQSFRKDNPAPFLDTLERNFQSFLQHVPTDGSEVDLQPLFLALTMDVSTEFIMGHSTNMLIQNADHTREQQFVDDYMVCSEEIIQQMQLGPLHSLKFNFAAKRAKKRVYEYLNDFIQESLNKSEDGPGSSFLAEMMDVVDDRTGLSHHILHILLASRDTTSGLLGNLFFFLAKKPEVYAKLRDEVLSVAGQEPPTASQLKDMTYLKWCVNESLRLHPVIPTNARVAVRDTTIPRGGGIDGKSPLFVSKGTAMFYNVYAMHRNEDVFGPKAEEFAPERWKDLRPGWGYLPFNGGARACIGQQYALLETHYVVARMAQAYSELQSRDDEEWMELYALALCSKNGCRVAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYL8</accession>
    <name>X0CYL8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Uracil-DNA glycosylase</fullName>
            <shortName evidence="7">UDG</shortName>
            <ecNumber evidence="7 9">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UNG1</name>
        <name evidence="12" type="ORF">FOQG_03170</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 7 9">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="7 9"/>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYL8"/>
    <dbReference type="eggNOG" id="KOG2994">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032162_2_0_1"/>
    <dbReference type="OrthoDB" id="10031947at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097510">
        <property type="term" value="P:base-excision repair, AP site formation via deaminated base removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.470.10:FF:000007">
        <property type="entry name" value="Uracil-DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003588">
        <property type="entry name" value="PRK05254.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003589">
        <property type="entry name" value="PRK05254.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003592">
        <property type="entry name" value="PRK05254.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264:SF0">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00987">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="11">
        <location>
            <begin position="119"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="297"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="310"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK95959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="368" mass="40836" checksum="D697750125550625" modified="2014-05-14" version="1">MSTLKRKAGASAGNDSKKPKANGNIASFFGAAPKPTGTGASAPAPAVKFDKAKWVASLKPEQKELLQLEIDTLDESWLAHLKDDLVTKEFLDLKRFLDREISSGRKVFPPRNDIYSWSRHTPFSNVKVVIVGQDPYHNDNQAHGLAFSVRPPTPAPPSLKNMYIALKKDYPTFEPPPNRGGLLTPWADRGVLMLNTCLTVRAHEANSHSNRGWEKLTQRVIDLVAQKRTRGVVFMAWGTPAGKRVQKIDRVKHLVLQSVHPSPLSASRGFFDCGHFRKANDWLVTRYGPEGEIDWALAPGTSTKAPATEADAKEAKSAEKKAEAIEKTKPEVVKKAEEGKENDAFDEDEEALEEALRLAEEEEKEKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYQ1</accession>
    <name>X0CYQ1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_08930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYQ1"/>
    <dbReference type="HOGENOM" id="CLU_3032463_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK87592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="55" mass="6200" checksum="4FD36EB4EFD5C5DD" modified="2014-05-14" version="1">MKPSLLVFGPKGDTDIILRKPNFRSHPELLPEAADPDAAEEENEDEKGEHKEQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0D025</accession>
    <name>X0D025_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Bifunctional purine biosynthesis protein ADE17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FOQG_08484</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis. Acts as a transformylase that incorporates a formyl group to the AMP analog AICAR (5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) to produce the intermediate formyl-AICAR (FAICAR). Also catalyzes the cyclization of FAICAR to IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PurH family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D025"/>
    <dbReference type="eggNOG" id="KOG2555">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016316_3_2_1"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01421">
        <property type="entry name" value="IMPCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.20:FF:000003">
        <property type="entry name" value="Bifunctional purine biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000003">
        <property type="entry name" value="Bifunctional purine biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.440:FF:000001">
        <property type="entry name" value="Bifunctional purine biosynthesis protein PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024050">
        <property type="entry name" value="AICAR_Tfase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005492">
        <property type="entry name" value="PRK07106.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692:SF0">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="13">
        <location>
            <begin position="38"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00054363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXK88047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="634" mass="69589" checksum="AC7DF9E8D5FF2C43" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0D0Y2</accession>
    <name>X0D0Y2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_02194</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. GNAT subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D0Y2"/>
    <dbReference type="HOGENOM" id="CLU_073102_0_0_1"/>
    <dbReference type="OrthoDB" id="5043642at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039135">
        <property type="entry name" value="NAT9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256:SF16">
        <property type="entry name" value="ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256">
        <property type="entry name" value="N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="34"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK96769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="228" mass="25751" checksum="5A935C53FBD23C84" modified="2014-05-14" version="1">MKINQNTAISTSKALLVPYEAHHVKQYHAWMQDPDIQEATASEPMTLDEEYENQQSWRTSSDKLTFIVCAPLTEDVSLVKAGTADADPLMRGDINFFLYPFESDDEDTETNTEGWVTGEVDVMIASPSHRGQGLGQAAVCALLVYIQKHLDGILAEYGAKELKGMMVKIKEGNKGSRALFEKLGFVQKGEVNYFGEILMTIEWDEIPRRDWWKGAGEEFREVSFEMVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0D130</accession>
    <name>X0D130_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_08232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D130"/>
    <dbReference type="eggNOG" id="ENOG502QUSG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018252_2_0_1"/>
    <dbReference type="OrthoDB" id="2590398at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK88392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="668" mass="75102" checksum="C96674A5EE519206" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0D1Q5</accession>
    <name>X0D1Q5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D1Q5"/>
    <dbReference type="HOGENOM" id="CLU_2558319_0_0_1"/>
    <dbReference type="OrthoDB" id="4986801at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXL00347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="91" mass="10411" checksum="56FB4C0392D163FA" modified="2014-05-14" version="1">MQWLFEDDFVQVLDVGGFIASWYEGGGQRLQFTAFSRPVPSKTMSVVAQVLFNFQYNCINNLKRVRVSRDRGEFRVSLGLAVSRCGSRTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0D2V9</accession>
    <name>X0D2V9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TAM domain methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D2V9"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_7_1_1"/>
    <dbReference type="OrthoDB" id="184880at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK97903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="39294" checksum="876BD88E81ED8625" modified="2014-05-14" version="1">MADITDPTTNPSYQVPELQQHDPPIEPDHPPPPTNDDIATDDGYDSAAPSAQSSSLASSVRDYQFENSRRYHKFKEGLYQFPNDLPEQEREDMKHTVAVHLLGGKLHNAPLDHPQKIIDIGTGTGSWAIDMGDEYPSAEVIGIDLSPIQPPWVPPNVRFLVDDAEAPWLYSENSIDLVHLRNMSTAIKDWPALLGQVYRALKPGGWIELPEFRWVYGCDDGTLRPDFTPPQMVANIRAALAKSGIEMHAAEKNPDRLHDAGFVNIRHEIKKVPVGPWPKDSNLKMIGLYNRSVIYDGLYAITIGPFTRALGWTPEEVEVFLVKVRKDLKDPSVHSYVHFHSLCAQKPFQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0D363</accession>
    <name>X0D363_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-hydroxybutyryl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00820</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D363"/>
    <dbReference type="eggNOG" id="KOG2304">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_2_0_1"/>
    <dbReference type="OrthoDB" id="5958943at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000009">
        <property type="entry name" value="Fatty oxidation complex, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075">
        <property type="entry name" value="3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075:SF5">
        <property type="entry name" value="3-HYDROXYBUTYRYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="7">
        <location>
            <begin position="34"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="223"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="39"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="4">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL00852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="319" mass="34168" checksum="DF98810E158AD5FA" modified="2014-05-14" version="1">MAASIFRMPSMAAARHARCFSSSPRQYAAAEVKKLGVIGAGQMGLGIALVAAQKAQVPVTLIDTSDKALDKGIAFAEKLLAKDVSKSRITQEQADSARSLLSTSTKMEDLSSADMVIEAVPELPNLKFDIFGKLAQICPKHAILATNTSSISITRIAAATTKDPTDTSASSRVVSTHFMNPVPVQKGVEIISGLQTSQDTLDTAIEFCKRMGKITSVSADSPGFLANRILMPYINEAIICLETGVGDRDSIDAIMKNGTNVPMGPLQLADFIGLDTCLSIMKVLYEETADSKYRPSVLLKNMVNAGWYGKKSGKGFYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>X0D6R5</accession>
    <name>X0D6R5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ASTRA-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_07152</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the ASTRA complex involved in chromatin remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the ASTRA chromatin remodeling machinery complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat ASA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D6R5"/>
    <dbReference type="eggNOG" id="KOG0322">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041940_0_1_1"/>
    <dbReference type="OrthoDB" id="7668193at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="418"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK90337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="433" mass="47496" checksum="3FC6D03DA54FC4BE" modified="2014-05-14" version="1">MDPSTPTPKSILRGHKSQVHTAAFIRSNERLITGDADGFVVLWDLTIMRPRAVWRPHEKALLGVGGWGDDRIITHGRDLKLIVWKLGEADEEHLSTALPVEEVATPRPQPWMLHLLEVNTLNFCAFAICSSVPGSVATASEVLIAVPNTLHSDAIDIYQLPSQRRIHTIKAGDKTGMAMCLALLHHKDALTLIAAFENGYATVHRLESDDQWVTAYHSQAHSQPVLSLSVYNDFFITSSADSIIAKHPIPTDLFFPLGDTVPPGSTERVVEIVDEEPKGKSLLSAGLTSSSSQGLKPPRKGVAWKDPLKAINTKHSGQQSLDIRSDGRIFATAGWDSKVRVYSTKTMKELAVLKWHQVGCYAVTFADVMISDQTEEENSTSNDNKATGSSNTRTGSLIRTGLSVKEQRIATARKTHWIAAGAKDGKISLWDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0D765</accession>
    <name>X0D765_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">tRNA nucleotidyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_07263</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TTI2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D765"/>
    <dbReference type="eggNOG" id="KOG2159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011026_0_0_1"/>
    <dbReference type="OrthoDB" id="445712at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110078">
        <property type="term" value="C:TTT Hsp90 cochaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CC tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000019">
        <property type="entry name" value="tRNA nucleotidyltransferase cca2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3090.10">
        <property type="entry name" value="cca-adding enzyme, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018870">
        <property type="entry name" value="Tti2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734:SF5">
        <property type="entry name" value="CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734">
        <property type="entry name" value="TRNA-NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10521">
        <property type="entry name" value="Tti2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly A polymerase head" evidence="7">
        <location>
            <begin position="91"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding" evidence="8">
        <location>
            <begin position="264"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK90487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1083" mass="121379" checksum="1B7F9F287BD31A96" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8N9</accession>
    <name>X0D8N9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_00303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8N9"/>
    <dbReference type="HOGENOM" id="CLU_1927664_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK99928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="131" mass="14577" checksum="1F3840FE2D9A52DA" modified="2014-05-14" version="1">MDHTRRLRVYLRLHSPSQPALQRPLEPTSPASGLGASILAPAETHLASRAHTHYKERALCAQAASTALWRRKRKTHFGLHALHLRTLRSAKPHFFKTWRENGMADNDTTGRAIATLSTAVKGRSHPKCSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9B3</accession>
    <name>X0D9B3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sterol regulatory element-binding protein cleavage-activating protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">FOQG_00154</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Escort protein required for cholesterol as well as lipid homeostasis. Regulates export of the SCAP-SREBP complex from the endoplasmic reticulum to the Golgi upon low cholesterol, thereby regulating the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. At high sterol concentrations, formation of a ternary complex with INSIG (INSIG1 or INSIG2) leads to mask the ER export signal in SCAP, promoting retention of the complex in the endoplasmic reticulum. Low sterol concentrations trigger release of INSIG, a conformational change in the SSD domain of SCAP, unmasking of the ER export signal, promoting recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi: in the Golgi, SREBPs are then processed, releasing the transcription factor fragment of SREBPs from the membrane, its import into the nucleus and up-regulation of LDLR, INSIG1 and the mevalonate pathway. Binds cholesterol via its SSD domain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat SCAP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXK99719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9B3"/>
    <dbReference type="eggNOG" id="KOG1933">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004183_0_0_1"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032936">
        <property type="term" value="C:SREBP-SCAP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008203">
        <property type="term" value="P:cholesterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045540">
        <property type="term" value="P:regulation of cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032933">
        <property type="term" value="P:SREBP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030225">
        <property type="entry name" value="SCAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46378">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46378:SF1">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="15 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="18" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="16" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="8 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 22" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 20" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="316"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="420"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="490"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="613"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="23">
        <location>
            <begin position="287"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="20">
        <location>
            <begin position="656"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="996"/>
            <end position="1016"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00045958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EXK99719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1119" mass="125084" checksum="6714A79C0DA7BA2A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0DC08</accession>
    <name>X0DC08_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_06037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DC08"/>
    <dbReference type="HOGENOM" id="CLU_2026826_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK92087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="122" mass="13889" checksum="BCF49242A3BA526C" modified="2014-05-14" version="1">MRLVRRGNFCENWPLLNEFFCGTIEYQDATTNHDSIARVILRERRNRAGHQLDRDSATGLMHGVDMSQLLCCNHDMLLSIDLDRISPTGQTYLFNFNSHRTRGSRILSTVASSPINVPLALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0DJH4</accession>
    <name>X0DJH4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acyl-CoA synthetase YngI</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_04588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DJH4"/>
    <dbReference type="eggNOG" id="KOG1177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_7_1"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF30">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="56"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="519"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK94552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="640" mass="69458" checksum="B6AD57820044B3B6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0DJH9</accession>
    <name>X0DJH9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Altered inheritance-mitochondria protein 31, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_04593</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Associates with the respiratory chain complex III/complex IV supercomplex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RCF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DJH9"/>
    <dbReference type="eggNOG" id="KOG4431">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6604018at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097250">
        <property type="term" value="P:mitochondrial respirasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050355">
        <property type="entry name" value="RCF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297:SF3">
        <property type="entry name" value="HIG1 DOMAIN FAMILY MEMBER 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297">
        <property type="entry name" value="HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="11">
        <location>
            <begin position="12"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="133"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK94557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="224" mass="25302" checksum="5C57A8A99A295052" modified="2014-05-14" version="1">MADAPPSLPGPMPSSFDGDQELQNERPMQKVLRKIKEEPLIPLGMGLTTLAFINAYRALRRGDSKQANRMFRARVAAQGFTVFAMLAGSMYYQKDREKSKELRQLQEQKDAEEKRQKWIRELEARDEEEKAMRARLEKKRQQVQAQRAEEARATAELQPEGNEASSNGGILSRIGLWPQGSKEEKKDDDKTAAQAVEDDASAKKKKNPKSSLGDLGEIISKRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0DXE7</accession>
    <name>X0DXE7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_01595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DXE7"/>
    <dbReference type="eggNOG" id="ENOG502RJB2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_765127_0_0_1"/>
    <dbReference type="OrthoDB" id="5096893at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK98842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="373" mass="40845" checksum="F2767B3FEE4D527D" modified="2014-05-14" version="1">MPVRSHYPKKISLRKSCKGLLRGRLEKRVKPSRTELQKVEKEKKRRSRPQASASSSSVAKPSTSSEAERLTAVASETNLLPEAPNALLGSNVESPGVQNQTLIAANNSNIDESNIIAVDPEGQSQAQTFRPLGYNTLATSAPYFEPYLLPISEEDIQYTAPSFTSSITQVSGLETYINDHFLLSEPTQTTSGADFGAPSIQSPLVHTQDFGNPSGLAWPLNMGQDVQQGLPPPAPDTSSSSSAGQELNLVKVTYDGGYSTRQVVEFDGRSNFNFIAQSYVDILQRSSPIQVISLPPGIGRKTQCPNGALINIEQILYAGIEFESHHLPFPPTRVYFVVYDDFRGEDGVHMTLGRDWVGKIEQAYPRVGYQGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0E2U3</accession>
    <name>X0E2U3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_00710</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="952271at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02674">
        <property type="entry name" value="Peptidase_C19R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00695">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUSP" evidence="10">
        <location>
            <begin position="103"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="450"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="307"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="407"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="810"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="923"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1283"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1325"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1392"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="826"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="946"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="988"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1007"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1288"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1420"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1450"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1477"/>
            <end position="1498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXL00628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1498" mass="166080" checksum="49CCE84D15CF2555" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>X0B3E0</accession>
    <name>X0B3E0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_18621</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658696">
        <property type="protein sequence ID" value="EXK76645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B3E0"/>
    <dbReference type="HOGENOM" id="CLU_038300_0_0_1"/>
    <dbReference type="OrthoDB" id="3251668at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF44">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK76645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="336" mass="37192" checksum="D8C6B999CC8E8B47" modified="2014-05-14" version="1">MTRSRGRCLNCKARKRKCDQARPECHPCSQRGMKCQGYSTPLRWVNGVASRGRFAGASVPDASLVAMQSLGLDSQSQDLSMDSETSAPTHDTASTASGSSAFSPPTLPAADPQDPIFQRCFLNSALHRLYNTEVTSWIKPFFKDMAQQSPALVMIAGSIQGYMDDGNRGMSVKSMEYVDLALQTFRRELSTRYETMHLGTICAGLLVCLLCLLQGQPWTMYFELIVNVYDLKTKLNTVGQISDDLYTQHLIEVLGVMDLPSMVIGRINPSIGVWKLLRRLQDGREQGRTNGIEVVSGVPRSLLDIFAGMADNDPEYTEGRLWSWPGHVGRDPNNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6Q2</accession>
    <name>X0B6Q2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17838</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658605">
        <property type="protein sequence ID" value="EXK77451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6Q2"/>
    <dbReference type="HOGENOM" id="CLU_114629_0_0_1"/>
    <dbReference type="OrthoDB" id="5081596at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="146" mass="15866" checksum="38A168DC18A12072" modified="2014-05-14" version="1">MFNVNAWMGQNTPVGANTNVALLTPQQMHTAYNTSFVPAGNPVTVEAYPQGYNIGGTWHAGQLHNAGNQRLARPVPDVVPFWTSHSLQQQDAAYQAGPPIPGTMWPTPAVGMTMHVPTLQVAQQNGMHINSVSPQGQIVWTWQGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>X0B970</accession>
    <name>X0B970_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_17006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658529">
        <property type="protein sequence ID" value="EXK78306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B970"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OrthoDB" id="433512at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF6">
        <property type="entry name" value="MSTA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="39"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK78306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="558" mass="62221" checksum="A6B274B4316901DC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAL8</accession>
    <name>X0BAL8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_16540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658501">
        <property type="protein sequence ID" value="EXK78811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAL8"/>
    <dbReference type="HOGENOM" id="CLU_133353_0_0_1"/>
    <dbReference type="OrthoDB" id="4886853at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="16034" checksum="4FDB14BE651AABF9" modified="2014-05-14" version="1">MSDNFEPTHASSDLGKWVEDLYYHIFCLTDDEATRNALEKGISPGFTANINHDTYTRQEFIDAIMRVRAVKQLSFQSTKDIQFWDAPDNSGAGCVAQYARFTDTYKETGIKVVSTTLLVADVRVVNGQRVLYELTEVLKVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0BAM4</accession>
    <name>X0BAM4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_19358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658786">
        <property type="protein sequence ID" value="EXK75878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BAM4"/>
    <dbReference type="HOGENOM" id="CLU_115492_0_0_1"/>
    <dbReference type="OrthoDB" id="5098699at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK75878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="135" mass="15024" checksum="C89FC085DA5887BF" modified="2014-05-14" version="1">MSPLSRESSPTTQEGFFYDTSGSAQQKRFHERLRNASAAGFYRSPLQDMPALPSSDGVEIRLGNSQRDPVLDSLTLGDSDESEIDEEGPDFVDLSQDIEEPELPPLPAPLPGFETNFSSTYHRIMNTLHLQTHTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB47</accession>
    <name>X0BB47_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_15996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2014-02" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979347">
        <property type="protein sequence ID" value="EXK79390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KI979347">
        <property type="protein sequence ID" value="EXK79391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB47"/>
    <dbReference type="eggNOG" id="ENOG502SKUZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054797_0_0_1"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08023">
        <property type="entry name" value="GH16_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF53">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="49"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK79390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="307" mass="34823" checksum="0A01860C2094B7A0" modified="2014-05-14" version="1">MPWKDHLKRLKNEFENLVGEPQAQNQQHPPPPGPPPPQQPIGGQQPGHVYWQPQFRPDVPVTQEWDAKIGNGPDGWGNQELQYYTADQQNAFHTPDGKLVLRAVANNSSEDHEKRYTSARLVSRQTLSRDQGVLTAWITSPCATGIWPAFWLLPQEPFSWPTDGEVDIAETWNGDLENHSCLHWGHHHEPHKHRVLGTKIPDMQHRPVRYDFAWLQSGGQPGQGRMIWYIDGRPVMKGDIPEGTRPMREMTILLNVAMGGNVCGGKTPADGYYDMVVHSLYMGSEPEYGGWHRFENDWAASPMGNTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BB84</accession>
    <name>X0BB84_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979611">
        <property type="protein sequence ID" value="EXK76083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BB84"/>
    <dbReference type="HOGENOM" id="CLU_2573962_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="81" mass="9354" checksum="CC80CE5BFAF14B41" modified="2014-05-14" version="1">MPMLSYEHLVELLVYFGLPSCNHQSIVVDPVMITLLAGAPRLPRVLFYRRTTTYYIPRNVNSIVVPELLRQGYEITDRSDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BC98</accession>
    <name>X0BC98_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658761">
        <property type="protein sequence ID" value="EXK76124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BC98"/>
    <dbReference type="HOGENOM" id="CLU_3242208_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="43" mass="4872" checksum="1564449743A399D8" modified="2014-05-14" version="1">MGFESNLYSKTIASAGFMVGNMRRYGIEVQALRRQLLSLSDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BE57</accession>
    <name>X0BE57_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18528</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979452">
        <property type="protein sequence ID" value="EXK76744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BE57"/>
    <dbReference type="HOGENOM" id="CLU_1938276_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK76744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="130" mass="13365" checksum="29BA08B8F0069366" modified="2014-05-14" version="1">MTGIAVGGPIGGFLGGLIGGLGGGFAGRWGAGKLTGLGEITGAEVEKLYETIMENYAVIGVYPDTSLSKRDVVTGMLDQSTSSKSVLVPMAGAVAADITNLEKRLFDWQQGSPEGLEVFLQGLRDAATSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0BEC8</accession>
    <name>X0BEC8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_14950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979337">
        <property type="protein sequence ID" value="EXK80515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BEC8"/>
    <dbReference type="eggNOG" id="ENOG502QVGN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_10_1_1"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936873" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="60"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK80515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="495" mass="53636" checksum="6D6F56E48D6D1297" modified="2014-05-14" version="1">MHLNTLQYLVIVLVANASKSLAVPTKREAVNSCLVQAKVPIDSKGTPTWTEDGTAYNLRLQFEPVAIAVPTTVAQISAAVACGSKHGVAVNAKSGGHSYTSLGFGGEDGHLMIELDRLYSVKLAKDGTAKIQPGARLGHVATELWNQGKRALSHGTCPGVGIGGHALHGGYGMVARKYGLTLDLMKGATVVLPTGKVVHCSKTENADLFWAIRGAGASFGVVAELEFDTFAAPEQITYFDIGGLNWNQQTAPQNLLDFQEFGKTMPAEITMQMFISKSGYSVDGAFVGTEAELKKALQPLLTKFNVQVSATTVDWIQLVTHFAGANVDVNPTSASYDAHDNFYASSLQAPELTLAQFKSFVDYISTTGQSSSHSWWLQMDISGGKYSAISKHKPTDTAYVHRDALLLFQFYDSVAQNQKYPSDGFNLITGLRQSISNTLKAGTWGMYVNYPDSQLKGDRATEMYWGSNLPKLESIKAKYDPKNIFRNPQSIKPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFF2</accession>
    <name>X0BFF2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_18105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979410">
        <property type="protein sequence ID" value="EXK77179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFF2"/>
    <dbReference type="HOGENOM" id="CLU_028279_1_1_1"/>
    <dbReference type="OrthoDB" id="3499148at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK77179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="387" mass="43390" checksum="53F7AB7DEB123CEF" modified="2014-05-14" version="1">MDASTIIQKLLSSLEQGQYPPSSAPVGLDKGLETFRSDEVSKLFVTKGFWAWLAYFFADEPTRQSLSTFSETEILQVADQVTKVKVNDSVNGLVQHTFYRSSRASQRRRLLEQLGIRDLPLQTHDISEPSALTSHPFISPPSPTVPNLAKRRRIDLRDDWCHQSNGTRHDSWCSLASDTGLQRNEPNTTSRSNDGQINTGLDTFGDTSFVPFAINPECDYVYPDASYLPFVFQAELGDMIIKRDSKASVLLSFGLGPDHCKILVDIEAPGVVYVALKFFDERIEEKRQQRAIVSPRGTRAVLLGNIRFENTEVKAWEIFLGELLINGVRHSPQRLEEVAQGKMLSTCLTVEIPPASNCPARLVLAVDPNTAAEVRARLWPRQHQYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFG4</accession>
    <name>X0BFG4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_14913</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658441">
        <property type="protein sequence ID" value="EXK80556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFG4"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_1_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF315">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE MDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="49"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK80556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="514" mass="57731" checksum="92360C267867AB79" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BFH3</accession>
    <name>X0BFH3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_14589</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Probable oxidoreductase that may play a role as regulator of mitochondrial function.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with COX5B; this interaction may contribute to localize PYROXD2 to the inner face of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BFH3"/>
    <dbReference type="eggNOG" id="KOG4254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019327_2_0_1"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10668">
        <property type="entry name" value="PHYTOENE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10668:SF103">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="6">
        <location>
            <begin position="30"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK80900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="533" mass="57769" checksum="D277FB24F864A1E9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BGM7</accession>
    <name>X0BGM7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_14252</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979334">
        <property type="protein sequence ID" value="EXK81290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BGM7"/>
    <dbReference type="eggNOG" id="KOG1541">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055194_0_2_1"/>
    <dbReference type="OrthoDB" id="2877at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000017">
        <property type="entry name" value="probable 18S rRNA (Guanine-N(7))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="9">
        <location>
            <begin position="52"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="10">
        <location>
            <begin position="212"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK81290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="280" mass="30532" checksum="0CA4F6C8F98B7939" modified="2014-05-14" version="1">MSRPEDTLAADVHYDDTEARKYTTSSRIQNIQASMTRRALELLDLKSPSLILDVGCGSGLSGEILSSIEPEEGGPHTWIGMDVSPSMLDIALQRDVEGDLMLADIGQGVPFRAGTFDAAISISAIQWLCSAETSDTSPFGRLTRFFNGLYASLKRGGRAVCQFYPKNDEQRHMITQAAVKAGFGAGMLEDDPGTKNQKLYLVLTVGGGDVQKKGGDITGVVEGMEGVDVEDARRQIKAHAPNMSKGSKAWIVKKKEQMERKGKIVKATSKYTGRKRRIQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BH20</accession>
    <name>X0BH20_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_17575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979377">
        <property type="protein sequence ID" value="EXK77739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BH20"/>
    <dbReference type="eggNOG" id="ENOG502SJ3N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002220_3_1_1"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="23"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK77739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="507" mass="56930" checksum="20CFEBE98DA406CF" modified="2014-05-14" version="1">MAPAGELGRRLIPCILDEMSRDEPDRVIYSIAKSADISKGFTEVTARKFANAVNKTAWWLESLVGKSESFQTIGYIGPHDIRYFLLNLACVKVGYEVIFLSPGNSIEAALGLLEATKCSLWVHPVDYPPYPLVEKIQQTWKLRIREIPTVAELLDATSSPHYPYTKTYDEAMGDTFCILHTSGTTGLPKPIYLSNGLLATMDAARILPPFEGDKGARPWATLYEKGDRLYSPCVLLHGPGIFMNLFATFLFDTHSVMGPVGVRPDMNLLASLADHGNIDIWHFMPVYVNELGQHPEVLQRFKSSKFIGAGGGPVSAELAAKVNEVVRVHNLFGTTEGLFMGDMLVEKEDFLWVSFHPYAGFEYTEIERGLFEQRAVKNEHWALHQGIFHTFPDVEEFNFKDLFIKHPTKPNLWLYMGRSNDIICLEDAQKLSPIETENMICAHPNVKGCVMIGNGQKFACLMVELKADTPRDPGTIEGFKESLGDIIDQADQNQLLRGYLRRDYKIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHB7</accession>
    <name>X0BHB7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_17447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979374">
        <property type="protein sequence ID" value="EXK77864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHB7"/>
    <dbReference type="eggNOG" id="ENOG502T4BF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1959711_0_0_1"/>
    <dbReference type="OrthoDB" id="5015698at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01111">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936936" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanovirin-N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="130" mass="14202" checksum="34972F81DC683590" modified="2014-05-14" version="1">MTKAIAVLLTLLGIAFAQIDRTCIDIAFNSETNTLSGKCQPRDNSGYIPSELDLNDCFGYDGTDITPTYHGNFAESCHGCEMFVAPDPWYGGAEYWIRCTCKGQSKKVAVPLEAAVAHEYVSNKDGHLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0BHY3</accession>
    <name>X0BHY3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_16857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979360">
        <property type="protein sequence ID" value="EXK78473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BHY3"/>
    <dbReference type="eggNOG" id="ENOG502ST51">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063299_1_0_1"/>
    <dbReference type="OrthoDB" id="5429716at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK78473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="299" mass="31603" checksum="98678231D1B98269" modified="2014-05-14" version="1">MPSARMNLGPLTTEWKYPDRCTVPVTDCSTCTNAWQGQTCGNNKDNTQGVLDDTDCWPPRKSSITAGNAVNGWGFYSPAFECPQGYETACTATGPETGNFNFQFSIQDDERVIGCCPSGYTCAQPGGPQTCTTIASRGSLQVASCSKQKTVLNWLTLPATVTDETSTVSLDGITIFAPMIQLNYREKDLSLSSGSTRSTTTVSVPAETGTSQSFSDGSSSGGLSTGAKAGIGAGVGVVGLAIIGAAFYLWRRRKRATLPAAELETKEDTKNAGSVLNYGSPPPQYPPVELDATNSRHEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIE2</accession>
    <name>X0BIE2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_17123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658536">
        <property type="protein sequence ID" value="EXK78199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIE2"/>
    <dbReference type="HOGENOM" id="CLU_3175458_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK78199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="47" mass="5644" checksum="84A5E61384EA570C" modified="2014-05-14" version="1">MGNDVSLMRTMLRGMLQETSTRLMSEQKQMLERLWDALMGISERRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BIR9</accession>
    <name>X0BIR9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PiggyBac transposable element-derived protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658526">
        <property type="protein sequence ID" value="EXK78359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BIR9"/>
    <dbReference type="HOGENOM" id="CLU_756584_0_0_1"/>
    <dbReference type="OrthoDB" id="5096864at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029526">
        <property type="entry name" value="PGBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019357">
        <property type="entry name" value="SCOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599:SF3">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13843">
        <property type="entry name" value="DDE_Tnp_1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10224">
        <property type="entry name" value="DUF2205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PiggyBac transposable element-derived protein" evidence="1">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="366" mass="41008" checksum="465A3051DA9E4806" modified="2014-05-14" version="1">MVPFTGRSKETTVIKNKPTPLGFKVWVIAQQGYFLQCLWHVKASSYKAVIVELPILKPYGKTGKLRTEIPLNNTQSVVVHLLNKPSTQTYHVFTDNLFSSPQLFRLLRQLGHGATGTARPNCGISTEMKQIKETGKAPNGIALQYNEVIQIAWKDSGIVLFLSTVLGGAPHERTPKKRKLPAKKGTKAEARRLQQVFNGDSFKMIPIPTVAAQYNDEMNHVDRGDQIRYPMYLPVLNDAQLPTTGLVGLSGRQPPSHILTPGQDTSEPLETAIEPDDTQAMSPRMTSEEVEALKCEMHTELRRLVKTIESPHAKALRDSLLLIFNRIEAVEKGNMKLDSNKKALQKYMEDLTSMHQTTTLDSHEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJ76</accession>
    <name>X0BJ76_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_13427</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658417">
        <property type="protein sequence ID" value="EXK82185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002124_0_0_1"/>
    <dbReference type="OrthoDB" id="427518at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051631">
        <property type="entry name" value="Ankyrin-KH/SAM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23206:SF8">
        <property type="entry name" value="ANKYRIN REPEAT AND KH DOMAIN-CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23206">
        <property type="entry name" value="MASK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DUF676" evidence="6">
        <location>
            <begin position="56"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="7">
        <location>
            <begin position="357"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="979"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1013"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1297"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1328"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1361"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1428"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1461"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="806"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1074"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1548"/>
            <end position="1622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1645"/>
            <end position="1772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="833"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="863"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1076"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1106"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1553"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1573"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1606"/>
            <end position="1620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK82185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1772" mass="194843" checksum="FF9ADFA16CFCBAB5" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BJT8</accession>
    <name>X0BJT8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658508">
        <property type="protein sequence ID" value="EXK78694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BJT8"/>
    <dbReference type="HOGENOM" id="CLU_038189_0_0_1"/>
    <dbReference type="OrthoDB" id="3481585at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK78694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="520" mass="61782" checksum="86CCC3BD635AEB25" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>X0BK16</accession>
    <name>X0BK16_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_16158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658476">
        <property type="protein sequence ID" value="EXK79208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BK16"/>
    <dbReference type="HOGENOM" id="CLU_3014222_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936358" evidence="1">
        <location>
            <begin position="20"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK79208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="56" mass="6519" checksum="69EB499A60BAC50D" modified="2014-05-14" version="1">MLFTTVWNWLLEQMGLAYTAKTTNAATYKTSNYYGNRDSHIQEVLGHKWQALIPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKF5</accession>
    <name>X0BKF5_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartate racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_13058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658411">
        <property type="protein sequence ID" value="EXK82635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKF5"/>
    <dbReference type="eggNOG" id="ENOG502SHHB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055360_1_0_1"/>
    <dbReference type="OrthoDB" id="187836at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047661">
        <property type="term" value="F:amino-acid racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1860">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033134">
        <property type="entry name" value="Asp/Glu_racemase_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004380">
        <property type="entry name" value="Asp_race"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00035">
        <property type="entry name" value="asp_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF7">
        <property type="entry name" value="ASPARTATE-GLUTAMATE RACEMASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198">
        <property type="entry name" value="GLUTAMATE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="Aspartate/glutamate racemase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00924">
        <property type="entry name" value="ASP_GLU_RACEMASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK82635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="231" mass="25611" checksum="0BA95DF6053AB37B" modified="2014-05-14" version="1">MKTLGLIGGMSWESTTTYYQEINRRVREIQGGLHSAQCIVFSFDFAKIEALQHAGRWKEAGEMLNDAAAKLKLAGADALVLCTNTMHFVSHGIEPASKLPLIHIVDPTAEAIIKAGYKSVGLLGTRFTMEKEFYKQRLVEKFGLKVIVPDDSDRDTVHNVIYQELCNGIIQENSREDYHSVIRRLKAEGAECLIMGCTEIGLLVDEAGSELPIFDTAKIHAIAAADWAMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0BKS0</accession>
    <name>X0BKS0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TIL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_16279</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658483">
        <property type="protein sequence ID" value="EXK79074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BKS0"/>
    <dbReference type="HOGENOM" id="CLU_156801_2_0_1"/>
    <dbReference type="OrthoDB" id="7695409at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19941">
        <property type="entry name" value="TIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036084">
        <property type="entry name" value="Ser_inhib-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051368">
        <property type="entry name" value="SerProtInhib-TIL_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002919">
        <property type="entry name" value="TIL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23259:SF70">
        <property type="entry name" value="ACCESSORY GLAND PROTEIN ACP62F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23259">
        <property type="entry name" value="RIDDLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01826">
        <property type="entry name" value="TIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57567">
        <property type="entry name" value="Serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004935806" description="TIL domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="TIL" evidence="4">
        <location>
            <begin position="26"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK79074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="79" mass="8351" checksum="7B271B6524CB488C" modified="2014-05-14" version="1">MKYSISLIALFVAGTIAIPAATAPKCKAGEQFFECGTACPLTCDKPEPRPCTKQCVPGCFCKEGTIRSQSGSCVSRNKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BM87</accession>
    <name>X0BM87_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Antigenic cell wall galactomannoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658407">
        <property type="protein sequence ID" value="EXK82966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BM87"/>
    <dbReference type="SMR" id="X0BM87"/>
    <dbReference type="eggNOG" id="ENOG502SR1T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091392_0_1_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF4">
        <property type="entry name" value="CELL WALL GALACTOMANNOPROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938704" description="Antigenic cell wall galactomannoprotein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="18339" checksum="1ABAB11FF05592A3" modified="2014-05-14" version="1">MRLSLLPLIALAGSAFASGDSISTAIDNISNATLALNKTVATWPQTLLGALPITTKSTLLLTEIHKGFVIARESEPLSLEETLQVAKATSELSADVELTINTIIAAKPNFDRLQVSPVILLNLNLQRALSQDFSEAVISKVPKDLQGNAKALVQGIDDSFARAISKYSKLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0BN00</accession>
    <name>X0BN00_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658401">
        <property type="protein sequence ID" value="EXK83570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BN00"/>
    <dbReference type="HOGENOM" id="CLU_038491_0_0_1"/>
    <dbReference type="OrthoDB" id="5083682at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="377" mass="42973" checksum="FC43B1DAFC8E4ECD" modified="2014-05-14" version="1">MCSNFLADINNNHAQECRVDWGPRFVCGIKAITALGQLLLVTRLELDVSTLEVPGSYDNRQTLNKKDTQRFDFTYAIPLLIALVLVLFFSGLLVRAIILSGMFLYALLILREGLEQSGYRTTLDEDIEDETRDLEIESEHLTQKHRLNTTIGKTLQDVGSSLAAGLGAIQETHDSYRAMFERFDSIKEEKIYRLHETINRISHIISMNETYRGNSTTDQWLRESQDELSELVIELRLTFYIIFEWSSLYTRISQDIFTPALREVQSFSSLATLINGIDLSSDRLKLRPAQQGQSTPRQTASLFSRSSMPIATIPPTYSADSDIYFSRSSASMAKDTMTLYKVAEFAEIELNKLYRERDNICTGESDRGLYHNYADSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0BN82</accession>
    <name>X0BN82_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_15140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658447">
        <property type="protein sequence ID" value="EXK80358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BN82"/>
    <dbReference type="HOGENOM" id="CLU_297182_0_0_1"/>
    <dbReference type="OrthoDB" id="9876900at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06423">
        <property type="entry name" value="CESA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022198">
        <property type="entry name" value="DUF3723"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43630">
        <property type="entry name" value="POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43630:SF1">
        <property type="entry name" value="POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12520">
        <property type="entry name" value="DUF3723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="4">
        <location>
            <begin position="78"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK80358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1014" mass="114862" checksum="F0A571AC210654AE" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0BNJ3</accession>
    <name>X0BNJ3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658402">
        <property type="protein sequence ID" value="EXK83426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BNJ3"/>
    <dbReference type="HOGENOM" id="CLU_000288_125_3_1"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="352"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="634" mass="70782" checksum="19EBB8AEBE148F94" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0BPR8</accession>
    <name>X0BPR8_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_14587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658433">
        <property type="protein sequence ID" value="EXK80898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BPR8"/>
    <dbReference type="HOGENOM" id="CLU_100997_9_0_1"/>
    <dbReference type="OrthoDB" id="2820488at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="37"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK80898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="153" mass="17819" checksum="4FD3BFF656A01A1B" modified="2014-05-14" version="1">MSKDKYSAEVEKIWKEHLTDQPPQTPQQIKAGKALIELFLATFVYHDYDRTRELVSKDYIQHNPSVGTGVDSIIEFAERETRDPNRPFQFNWKRIFVDGNYVIAHNHVENGDGTDGVRVVEILRYENGLFTEHWDTVTPVPPKSEWKNQNGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BQI9</accession>
    <name>X0BQI9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BQI9"/>
    <dbReference type="eggNOG" id="ENOG502RS72">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043073_0_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="323" mass="36414" checksum="74F6E8BFAD299ACA" modified="2014-05-14" version="1">MDGGLTRKRWEAKNSEKNLKFPSSQQRTHKNEYGVEAEDLTVNKVSTDFKDNSKSVIWVDIFDPINGPSFKPSPLKPIPLFMQRPPSPTIHERQRRSTAAETYLQPPHDLRKQHSAPCSVCPSESPVRSRSSEHRTPRQPSPTLPKTPPSSPSRSRNTQKIPEHDYLDMIDRSEVQHKQAVSWVSVEPLKRPSSRLAPSRRAEANGSEAESSAYRTPPEYPDQVLRTPYPLPLSNVKTASPLHAQLTSHSQRTVHATPQSSEYLDRYQPATTRSTQNQGVRRLRRIDASVTEEGLAKMKPGQSEGGEWGGKVGSELRRFFTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0BRH2</accession>
    <name>X0BRH2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658394">
        <property type="protein sequence ID" value="EXK84770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BRH2"/>
    <dbReference type="HOGENOM" id="CLU_2687891_0_0_1"/>
    <dbReference type="OrthoDB" id="5069902at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="75" mass="7961" checksum="F1FB58604FFAF0E1" modified="2014-05-14" version="1">MYPSAGFTPESSAPTSPTEAAHGYFLSLIPAEFGPQPIQCPHSTRCECTGCSGCKNEISNWSTMQCSNCNINCPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BT55</accession>
    <name>X0BT55_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979330">
        <property type="protein sequence ID" value="EXK82118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BT55"/>
    <dbReference type="eggNOG" id="ENOG502S2VY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040944_0_0_1"/>
    <dbReference type="OrthoDB" id="2522565at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="494" mass="56930" checksum="91BC4F50CF89342A" modified="2014-05-14" version="1">MRVSNMRLPNSLRNLSVRLSSIRIPHPHPRRIILYVTTTALLVVMILTFTMSDRLFGNGHSGYDPLLSRTNDYRLLTSTRNNLGFYNSINVKKTGQKIMNPTLLELPKGSKHEFLVIARAPHVDQDIKGKKYRRAQQVATFVSLTWDAFGRPELTADNDWHKMLVEDFTEAQGPEHHCKNQPDMDKYIGPEDMKLFWRKNGTPMLIFTHQVDDENLCEGMYIVDARAAVPELVKQMGKHAKELPGIEFDKPVLLRRQPPEGQESDARYQREKNWAPVYSPFSADDDEMMFMVEPSQLYRFNSTDEPVQNMEAEPESAVDEPFPPDNEKKTWHSAEKTCMNDVMLTDKRVHQSTPMLSLTLCNRGACEPMENNTVLMGMVQMRYDPPQYTNTWYDHRIVVYSPVAPYHMMSVSKKLTYHGETNSRYIWTGSMVYHGDQPTQRSHGYLDDEIWLSFGIGDSSPGWLDIKAEELVLDHYFCQGATPGYRSSIKKHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTQ9</accession>
    <name>X0BTQ9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_10356</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Cd(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48775"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the class-II DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="6"/>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTQ9"/>
    <dbReference type="eggNOG" id="ENOG502SIEB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026885_1_0_1"/>
    <dbReference type="OrthoDB" id="2338at2759"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002480">
        <property type="entry name" value="DAHP_synth_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337:SF0">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01474">
        <property type="entry name" value="DAHP_synth_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0104">Cadmium</keyword>
    <keyword evidence="5" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="253"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602480-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK85560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="435" mass="47869" checksum="939C57111A76F927" modified="2014-05-14" version="1">MHAEIPTYNLRLSTGYRNRKSAASALVKEITTNGNGAIHWTPDSWRSKYAAQAVEYNDTNALEDVCASLKQLPPLVSRLEIEQARVRFYHVALGRGFIIQGGDCAESFHDIQHDIIHRKVDLLHQQSQILEDAIGKPVIPLGRIAGQYAKPRSNPLEVLPNGDKVHAFRGHIINSEGLEDRNPDPKRLMLGYFYAAATQNSIRHVTGLANSVPEKAFNKCHLYTSHEALHLPYESALTHESYNLSATSIWLGERTRQLDGAHVEYARGLRNPIGVKIGPTATAADVIALLDTLAPDTAQYGKVTIITRMGHGRVGQLLPAIIRAVQLSGHLPIWMCDPCHGNTFTTPDGIKTRRVEDLLAELEETYAAHRSLGSHLGGIHLEQTGDDVTECLGGPSCENEGDLKACYESLCDPRLSGEQALDLVQRFAGFVKNFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BTX7</accession>
    <name>X0BTX7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_10698</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658390">
        <property type="protein sequence ID" value="EXK85341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BTX7"/>
    <dbReference type="HOGENOM" id="CLU_002341_0_1_1"/>
    <dbReference type="OrthoDB" id="5086500at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056693">
        <property type="entry name" value="DUF7791"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25053">
        <property type="entry name" value="DUF7791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="297"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7791" evidence="3">
        <location>
            <begin position="570"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK85341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1089" mass="123976" checksum="15542675DAEAF815" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUS3</accession>
    <name>X0BUS3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_13377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658416">
        <property type="protein sequence ID" value="EXK82239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUS3"/>
    <dbReference type="HOGENOM" id="CLU_1189967_0_0_1"/>
    <dbReference type="OrthoDB" id="10270783at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK82239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="251" mass="28575" checksum="7765D04C07D7A54F" modified="2014-05-14" version="1">MSHSQPYKPLKGQSYRPLKGYSFYLTDLVKPKLEGKISKNGGTLHKNYNYKRKGTMGTKYFVCSKAEYRSFRDRLAGSLSDKVDISEKDYDAMLEAYELGEKGMLDTGCLEAISDNSHAWNPIDWADSYGKKEPERRCDVWIQQMQAHGVYRLSSLLDEAIDVNGEDDMEAKSFDREYTRIADIIKDHPDGLALVNNWKDKYNELIALIRDVREVVGTLVQDETPVPDETPVQDETSVQDEGYESASTTDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0BUU2</accession>
    <name>X0BUU2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NCS1 family nucleobase:cation symporter-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_12948</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658410">
        <property type="protein sequence ID" value="EXK82673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BUU2"/>
    <dbReference type="HOGENOM" id="CLU_026016_2_0_1"/>
    <dbReference type="OrthoDB" id="2116389at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF5">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK82673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="492" mass="53597" checksum="276FFA003BC2B4CC" modified="2014-05-14" version="1">MSEKTNTLVADPPVEVSEAESQVLSCSSIWLYRLRRWGLETRGMQPVPIEERTDTRFINIFFMWFTMNVNVLPIVTGMLGTLGFGLSLKDCSLLILFFSLLCCVFPAYCSTFGSRTGLRQMLISRFTFGYYLIVIMVILNLCTNAGFGIICSVTGGSTLAAVSSGSINSTVGIVVISIIAMVVSFIGYNFLHQYERYSWIFNLVAIVIATGVGGKHLSNQAEQPAASASTIVSYGGVIAGFIIPFSALAADFSVYCHPRVSTWRIFAYTYAGIFFPVVSLMILGAAIGGATPNVVSWKDGYDRFSVGGVMQAMLLPAGGFGRFVAVMLSLSVIGNLAASIYCISLNFQLLAPFMLKIPRSLFTIVYTVVAIPVSIQAAKSFFDSLENLMYLISYWAAGYVAVIGTEHFVFRGADCSSYSPDHWDQPTKLPTGLAAIGAMGIAFCLTVPCMSQEWYTGPIAKTTGDIGFEVELVLAAFLYVPLRWVELKLRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>X0BVZ7</accession>
    <name>X0BVZ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="12">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_10004</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 18">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="12"/>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658386">
        <property type="protein sequence ID" value="EXK86369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02735">
        <property type="entry name" value="RNAP_I_Rpa1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01435">
        <property type="entry name" value="RNAP_I_RPA1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.180:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2850">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047107">
        <property type="entry name" value="DNA-dir_RNA_pol1_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015699">
        <property type="entry name" value="DNA-dir_RNA_pol1_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF11">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 12 16" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="15">
        <location>
            <begin position="363"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="268"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1368"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="407"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1374"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1420"/>
            <end position="1431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK86365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1676" mass="184749" checksum="70BE061EBF757AAD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0BW03</accession>
    <name>X0BW03_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658387">
        <property type="protein sequence ID" value="EXK86086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BW03"/>
    <dbReference type="eggNOG" id="ENOG502SVIK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_966860_0_0_1"/>
    <dbReference type="OrthoDB" id="4309089at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="278" mass="30345" checksum="EF84E6950E53459A" modified="2014-05-14" version="1">MSLLSVYAALEPYLDIPFNASLSGILFLAYRCLISKPGLLLTIVYTTSAIIVLFDRTSTKGEMAKTMAELPLGLGSVLLFIVASRPTKAQWLHAFTIYVNFAVYGNILMMVATPSGGSFRGICCKAACLSLSAWIVLQGYSVQWKTIMLHDDLFVFTAASKSWIFTHAVYRFILLTLPCFGSGRRHRLMEVYSLGLTYLLSWSTGLPFEYCFGMADTVVAPAVTAWSSISKTFNLIPRDAGKDRSSASGISDTGDFYLGIVALAVAAYACFNMASQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0BX01</accession>
    <name>X0BX01_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ornithine cyclodeaminase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_12709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ornithine cyclodeaminase/mu-crystallin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658407">
        <property type="protein sequence ID" value="EXK83039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BX01"/>
    <dbReference type="eggNOG" id="KOG3007">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042088_0_1_1"/>
    <dbReference type="OrthoDB" id="41492at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="entry name" value="ornithine cyclodeaminase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812:SF19">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK83039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="40188" checksum="445B4062EEDAB51C" modified="2014-05-14" version="1">MPFTVLSDANVNHILDTLSPSDVTDLANALEQALIQYSCNNEQQYQPHRAVVNRDGQVSLFMPGTTDQLIGVKIVGVTPSEKLKPSEAGLKSVLTLCDARGQAIGTLNAAALTAFRTALGSMLPYRFRRNTENIVVFGAGKQALWHIRLALLLKEEDIKSVTIVNRSAERTQQLIDSLKSNDKSTWPSHINLQAFDPKEDRDAAMEALVVDADVLFFTTPSTEPLFPASYLTSEKALSKTRYLAAIGSYRLDMQEIDPELLKQVINPSGPFSSVGYQGGSVAVDSREGCLQEAGELVKAEIPTDKMLEIGHLFQTKNTENPNDLTKWLESGFVIYKSVGTGVMDLSIGQELLRLAKVKNVGLTAEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZL0</accession>
    <name>X0BZL0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sterigmatocystin biosynthesis monooxygenase stcW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_08953</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZL0"/>
    <dbReference type="HOGENOM" id="CLU_006937_6_3_1"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF4">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK87615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="588" mass="65906" checksum="E1BA5E6DBA9D6CC3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0BZR1</accession>
    <name>X0BZR1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipase B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_11742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658398">
        <property type="protein sequence ID" value="EXK84009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0BZR1"/>
    <dbReference type="eggNOG" id="ENOG502QSW8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029537_0_1_1"/>
    <dbReference type="OrthoDB" id="4605274at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053228">
        <property type="entry name" value="Stereospecific_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37574">
        <property type="entry name" value="LIPASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37574:SF1">
        <property type="entry name" value="LIPASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004938970" description="Lipase B" evidence="1">
        <location>
            <begin position="19"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK84009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="49384" checksum="DFA39CB6CDABCF6A" modified="2014-05-14" version="1">MRFSALLVALALTGAGLAAPYNSNGASLIERRQALTGLFNGVNNALAVTASGLLDELGDALNKGDREKTLDTLQKLKATKKPKNVGEASSITKKVAKSEPDNIVEYSARLIANGIVSGSTDDILGYAQGLGSVENGNNNQNPDPPKSVFPRAASCDAPYTVSENKLRSAIYIPDTFTYGKKLPVILFPGTGSTGYTAFRGSFIPLLTGVDWADPVWVNVPELLLGDAQVNAEYAAYALNYIASLSKRSVAIIGWSQGNIDTQWAFKYWPSTRKVTTDHVAISANYKGTVLANFVDLSGITNTPSVVQQEAGSNFIKTLRSDGGDSGYVPTTSMYSSFLDEIVQPQEGLGASAYLLDQRIVGVTNAEVQKVCAGKPGGSFYTHESMLANPLSFALAKDALTHEGPGKISRLDLGTVCASSLAPGLGLEDLLITENAIVIAGISLVTYLPKVKQEPAIKEYALNTAGTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C047</accession>
    <name>X0C047_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_11649</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979326">
        <property type="protein sequence ID" value="EXK84144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C047"/>
    <dbReference type="HOGENOM" id="CLU_2819454_0_0_1"/>
    <dbReference type="OrthoDB" id="4985240at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK84144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="72" mass="8764" checksum="AC1AC3D432429110" modified="2014-05-14" version="1">MKSYQPINPDDQESDEDNIFKEHLELFCGSMEYHTDNFETACRDARDELLDKLRHKFKELRESLRHHIKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0C0M2</accession>
    <name>X0C0M2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FOQG_11572</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">54005</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658397">
        <property type="protein sequence ID" value="EXK84314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C0M2"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_12_0_1"/>
    <dbReference type="OrthoDB" id="2431938at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="537"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="572"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="607"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="667"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="707"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="737"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="4"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="288"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXK84314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="777" mass="84702" checksum="24D537C4A04D81D4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1I0</accession>
    <name>X0C1I0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7580 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658392">
        <property type="protein sequence ID" value="EXK85043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1I0"/>
    <dbReference type="HOGENOM" id="CLU_026305_3_1_1"/>
    <dbReference type="OrthoDB" id="3565018at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056002">
        <property type="entry name" value="DUF7580"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186:SF4">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24476">
        <property type="entry name" value="DUF7580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7580" evidence="1">
        <location>
            <begin position="194"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="570" mass="63836" checksum="42717B089A0D4685" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0C1T1</accession>
    <name>X0C1T1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_18529</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979453">
        <property type="protein sequence ID" value="EXK76737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C1T1"/>
    <dbReference type="HOGENOM" id="CLU_007383_8_0_1"/>
    <dbReference type="OrthoDB" id="300709at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF14">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK76737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="350" mass="39084" checksum="1001789A21DA7BAF" modified="2014-05-14" version="1">MVDLKEIAVIGGTGAQGMPVVQALSQSGRYRVRVLTRNPESSRAKQLAALPNVSLLQGTQDNQQDLHNIFQGVYGAWVNLDGFTLGEKDELFYGFRAYEIARSEHVQHYVWANIEYALEIANFDEKYHCGHMESKGRVGKFILAQGQETMKSTLFSTGPYMDMLIDGMFTPQEQPDGSYLWVNPAPSEVKLPLIALCDVGVYNLWIFDNPSESAGIDLSVVTDNVSFEEIARVFKEVTGKPAAHKSVPFEKYAPLAEPYPGAYVNWALGPDAARDDSVMSWRENFGAWWRYWGDGITAPRDTEILDRIHPKRIKSLAAWMQHVGYDGASPGGVLKMVEDWAGKMAARPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C242</accession>
    <name>X0C242_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_08310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C242"/>
    <dbReference type="HOGENOM" id="CLU_2996518_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK88490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="57" mass="6280" checksum="7636BB05A061A022" modified="2014-05-14" version="1">MHLATQDLCTNQDVIVKSQRLKLATATPQSQLEETCEGQYSLTDALLSQTVVQDDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0C3F1</accession>
    <name>X0C3F1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_10465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658388">
        <property type="protein sequence ID" value="EXK85673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C3F1"/>
    <dbReference type="eggNOG" id="ENOG502RJ40">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142374_0_0_1"/>
    <dbReference type="OrthoDB" id="5104711at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936154" evidence="2">
        <location>
            <begin position="19"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK85673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="185" mass="21188" checksum="C1CC8E1623A877D2" modified="2014-05-14" version="1">MKFSTFIAPLISIPLVFASPNPNNYPPPPKTKTVTATVTHTVTKPIYKPPITKTETVTKKYPVTKYETETVTKYKWKPPVTKTEYVTKWKPPVTKYVTKTETDTVTKWKPPVTKYVTKTQTDTITKWKPPVTKTKTETDTVTKYKWKPAITKYKTETVTKTVTKQPYPTYHKPGGGHKEGKDYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>X0C4M2</accession>
    <name>X0C4M2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-xylosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658378">
        <property type="protein sequence ID" value="EXK89355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C4M2"/>
    <dbReference type="eggNOG" id="ENOG502STXT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095402_0_1_1"/>
    <dbReference type="OrthoDB" id="4156665at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK89355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="17193" checksum="6DF7D769B86CAF40" modified="2014-05-14" version="1">MMRGEIPSRHHRAFGQRRLAKNPNLQRKLEQMALPLAPLVQLTTGAVHPSFPTTVLNFWLLTDEQLESLAHFYHQRTPSPWTNQYPCPVTWRSDLPLEEKRRKMGKFIGLRGCESPILLKTEEEILAEARKARLAAEEDLWRRKHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0C563</accession>
    <name>X0C563_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Long-chain acyl-CoA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_17410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658562">
        <property type="protein sequence ID" value="EXK77897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C563"/>
    <dbReference type="HOGENOM" id="CLU_000022_45_2_1"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="110"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK77897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="692" mass="76517" checksum="FE5C7E1EA7874632" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C6U1</accession>
    <name>X0C6U1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">THOC5 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_07343</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK89852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C6U1"/>
    <dbReference type="eggNOG" id="KOG2216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082754_0_0_1"/>
    <dbReference type="OrthoDB" id="20582at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019163">
        <property type="entry name" value="THO_Thoc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375">
        <property type="entry name" value="FMS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375:SF3">
        <property type="entry name" value="THO COMPLEX SUBUNIT 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09766">
        <property type="entry name" value="FmiP_Thoc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK89851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="24291" checksum="87770D9120491FA6" modified="2014-05-14" version="1">MAIDKIITDPRLCAVLQISDQARDQAGALLSLGEQSCSEGPPSAEAQAEIAKQQKLLFTTMAHLKGLHRNVCFSARETKSQTAESRQEVDRLHLQLQNLYYEQRHLQGEITACESYDHKYQQLPLIPVEEFLAQHPEHENDDENTLMVARIDHERSEREALEQQRQELLKRKQKLIADNKRRKDDLANLDNDLEKFIDAAKPIQKLFEKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7D2</accession>
    <name>X0C7D2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_07137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658375">
        <property type="protein sequence ID" value="EXK90320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7D2"/>
    <dbReference type="HOGENOM" id="CLU_2171145_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK90320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="110" mass="12357" checksum="98D8E23FB5E46C0E" modified="2014-05-14" version="1">MPIGQRKVRRFAYWQGVYSPLEAIGSEVGARLELYGGKVGKIAPRSFYTLRVFVRMPLAYSATLNLQTSKLRLTKFEDQLSMEIGGWVPVEVLASDPPANLAPLHRGREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0C7G5</accession>
    <name>X0C7G5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chromatin structure-remodeling complex subunit rsc7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_07479</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C7G5"/>
    <dbReference type="OrthoDB" id="5598844at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013933">
        <property type="entry name" value="CRC_Rsc7/Swp82"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF5">
        <property type="entry name" value="LOCALIZATION PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08624">
        <property type="entry name" value="CRC_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="337"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="422"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="481"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="427"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="482"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="519"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="549"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="610"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK90086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="633" mass="68706" checksum="90CD1846199B3507" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0C901</accession>
    <name>X0C901_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_09005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658382">
        <property type="protein sequence ID" value="EXK87668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0C901"/>
    <dbReference type="eggNOG" id="ENOG502QSWT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011786_1_0_1"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04842">
        <property type="entry name" value="Peptidases_S8_Kp43_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034058">
        <property type="entry name" value="TagA/B/C/D_pept_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF5">
        <property type="entry name" value="PEPTIDASE S8 FAMILY WITH PROTEASE-ASSOCIATED DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="6">
        <location>
            <begin position="210"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK87668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="658" mass="70827" checksum="BA669AACF5318989" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0CAG4</accession>
    <name>X0CAG4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA polymerase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FOQG_08564</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYBBP1A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979323">
        <property type="protein sequence ID" value="EXK88183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CAG4"/>
    <dbReference type="eggNOG" id="KOG1926">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005212_1_0_1"/>
    <dbReference type="OrthoDB" id="342531at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000182">
        <property type="term" value="F:rDNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007015">
        <property type="entry name" value="DNA_pol_V/MYBBP1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213:SF2">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04931">
        <property type="entry name" value="DNA_pol_phi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="696"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="714"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="755"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="770"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXK88183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1008" mass="112753" checksum="AE7CC2BEAF2B0FB8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CB64</accession>
    <name>X0CB64_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Magnesium transporter protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_06746</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OST3/OST6 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CB64"/>
    <dbReference type="eggNOG" id="KOG2603">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052855_1_1_1"/>
    <dbReference type="OrthoDB" id="67566at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000302">
        <property type="entry name" value="Oligosaccharyl transferase subunit (Gamma), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021149">
        <property type="entry name" value="OligosaccharylTrfase_OST3/OST6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692:SF0">
        <property type="entry name" value="GH11935P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04756">
        <property type="entry name" value="OST3_OST6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004939245" description="Magnesium transporter protein 1" evidence="10">
        <location>
            <begin position="20"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK91366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="36089" checksum="1860DFE937A656D7" modified="2014-05-14" version="1">MRFLRSLLSFAVLATGVAAAKKSSAERFDEFHAKQSSTPLKLKESTYKTLTSTPRDYSVAVLLTAADARFSCQLCREFQPEWDLLGKSWAKGDKAGNSRLIFGTLDFVDGREIFMSLGLQTAPVLLLFQPTVGPHAAQKPEPLRYDFSAGPPTAEKVHSWLARQLPDRPHPAVKRPFNYAGWAITITIVLGVITAGVVAWPYVSHILQSRNLWAALSLMTILLFISGHMFNHIRKVPYVTGDGRGGVNYIASGFQNQLGLETQVVAAIYGVLSFCAISLAIKVPRIAEAKSQQVAVIAFGGALFLVNSFLLSVFRIKNPGYPFSLPPFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDC6</accession>
    <name>X0CDC6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H3-like centromeric protein CSE4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">CENP-A homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">CENPA homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_06069</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of centromeric nucleosomes, where DNA is wrapped around a histone octamer core. The octamer contains two molecules each of H2A, H2B, CSE4/CENPA and H4 assembled in one CSE4-H4 heterotetramer and two H2A-H2B heterodimers. Interacts with the inner kinetochore.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDC6"/>
    <dbReference type="eggNOG" id="KOG1745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078295_3_3_1"/>
    <dbReference type="OrthoDB" id="842664at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000087">
        <property type="entry name" value="Probable histone 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810:SF1">
        <property type="entry name" value="HISTONE H3-LIKE CENTROMERIC PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810">
        <property type="entry name" value="HISTONE H3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="35"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK92156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="133" mass="15055" checksum="4B448D0D96B42A29" modified="2014-05-14" version="1">MPPRKSKASGAGKSRPSDVQAGDPVPVRAKRRYRPGTVALREIRHYQSGTKLLLRKLPFARLVREIALTMRPRDEGLRWQSQAIMALQEAAEAYMVHLFEDTNLCAIHAKRVTIMQKDIQLARRIRGIWGGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDM3</accession>
    <name>X0CDM3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Ribosome biogenesis protein NOP53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May play a role in ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the NOP53 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK92276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDM3"/>
    <dbReference type="eggNOG" id="KOG2823">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035888_1_0_1"/>
    <dbReference type="OrthoDB" id="5072at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011687">
        <property type="entry name" value="Nop53/GLTSCR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211">
        <property type="entry name" value="GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211:SF7">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07767">
        <property type="entry name" value="Nop53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017302">
        <property type="entry name" value="Gltscr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="159"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="218"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="311"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK92276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="439" mass="50804" checksum="F298033B6DB6CD3D" modified="2014-05-14" version="1">MPVLQSKNATGGDAPKQFNQPSRKGKKAWRKNVDVTEVQKGLEELNKEIIAGGVIKEKSSEDLFTLDTKGDAGLPKRFNKHIKKGLKADEIINARSPVPAVSMRKRPGDKTTNGILPVKRQRTDWVSHKELARLKRVADGEHQNTVQVQDATYDIWDMPVEPKAKDPENFLEEEVKPKAPKSMKKEPLSLLESGKQVPAVLKPTGGYSYNPDFNEYTQRLEEESEKALEAERKRLEKEEQERIKQEAAARSAAEAEAAEARANLSEWEEDSEWEGFQSGAEDDKPSAKRPQRKTQAQRNRIKRRKEEERLAKHKAALKAHRRQAQRIQEIAEEIEERDRNKALVLQKDDETDPIDELRAEKLRRKQLGKYKLPERDLELVLPDELESSLRRLKPEGNMLRDRYRSMLVRGKVESRRHIAFHKQAKRKFTEKWTYKDFMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0CDU1</accession>
    <name>X0CDU1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_08227</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658379">
        <property type="protein sequence ID" value="EXK88994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CDU1"/>
    <dbReference type="eggNOG" id="ENOG502SXC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_715813_0_0_1"/>
    <dbReference type="OrthoDB" id="4866377at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937118" description="Extracellular membrane protein CFEM domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK88994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="41010" checksum="50B725FF60342DD8" modified="2014-05-14" version="1">MSRIFSVLLLFLPLALSADFESVTISANLDNVGHACISKCLYYTLLSDMGRAMGCDDPYDNNCYCATAAASANKADGFMSKCATSLCSAGDRSRDLTSMQSYYASYCMGAGFTQPGATEWYNPAEATEEPTNEPTAESSGGSDARPSRTANSGGDGTSTHMTIVTQTAEDGAARTQVIVEATSTYWVNSDGSPASSKNEDGGTSVVKIGVGIAVPVVVIAAGLFAWWFIRRRNQQKAQYPHTSQPLSEVTTGGGPAVVASVSPSTPERRDTLPRKPVGASTISSVSSLSKTNELSGIGVQRELSGREVHPFPNMTPSPPLQVAGQHEMSGEGWRPNLEMDGRDARVEMSGEARPPELPGYINSANAYTPHESVQRWELPDNSRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CF80</accession>
    <name>X0CF80_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_05850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658370">
        <property type="protein sequence ID" value="EXK92846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CF80"/>
    <dbReference type="eggNOG" id="ENOG502S0S8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009124_1_0_1"/>
    <dbReference type="OrthoDB" id="1749473at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="212"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK92846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="834" mass="91583" checksum="CC5ED26CFD2E6A93" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>X0CG03</accession>
    <name>X0CG03_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_05467</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CG03"/>
    <dbReference type="eggNOG" id="ENOG502S2IA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009648_0_0_1"/>
    <dbReference type="OrthoDB" id="5370478at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="6"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="535"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="549"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK93340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="616" mass="69693" checksum="05026E8EE0F2A359" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>X0CHZ0</accession>
    <name>X0CHZ0_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CHZ0"/>
    <dbReference type="eggNOG" id="ENOG502RH53">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1147220_0_0_1"/>
    <dbReference type="OrthoDB" id="5230713at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK94050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="242" mass="27947" checksum="6F0E7750B36E642E" modified="2014-05-14" version="1">MLRGTTSNVPKVPLFGVPKRRKQRQQQEQEQKDKEEKLRLQALEEAEFATKAETSDFLLYYLERSPFKDQSDQISIAWENLPSLGELESFARLDKTAGTQACRRLFKAVVIWDDLGLDLWETLNSTFHPESDEEDSDDDLLDEISEEPVGWDHASPRRSRSRASSRTSSSETHNSERSRQVSSERQDQRERSRDSRKTASARDQSVNGRLPPRRPMGLQGGMISEYYDSPSRYRVPKIVRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJL9</accession>
    <name>X0CJL9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein BOI2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_06560</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658373">
        <property type="protein sequence ID" value="EXK91036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJL9"/>
    <dbReference type="eggNOG" id="ENOG502QSRX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011433_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13316">
        <property type="entry name" value="PH_Boi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09535">
        <property type="entry name" value="SAM_BOI-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11886">
        <property type="entry name" value="SH3_BOI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.50:FF:000082">
        <property type="entry name" value="Polarized growth protein boi2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035551">
        <property type="entry name" value="Boi1/2_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037370">
        <property type="entry name" value="Pleckstrin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12092:SF16">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12092">
        <property type="entry name" value="PLECKSTRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="14"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="6">
        <location>
            <begin position="226"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="5">
        <location>
            <begin position="703"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="79"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="297"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="544"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="620"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="880"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="475"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="571"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="662"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="915"/>
            <end position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK91034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="935" mass="101684" checksum="F3B3F317039958A1" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CJN7</accession>
    <name>X0CJN7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ceramide glucosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_04646</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CJN7"/>
    <dbReference type="eggNOG" id="ENOG502SICP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_561441_0_0_1"/>
    <dbReference type="OrthoDB" id="5096213at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK94640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="55547" checksum="0E2E9937FADA7DC9" modified="2014-05-14" version="1">MGFSLQVAGPAAIVSVVVLSIIIVIRLTGFAILQYGRRRYPEPHGRLNFPKEISVILTIRDPNDPNLLDYVRSILNNKPEQLFITTSDRKAQHRVDGKLTGLRFAYSATQISVDAVNEPSRRREIAHALASVSTPLTVLTDQGVHWSSRFLESALIPFADSRVGCVTVPMIARKRDGIWGSFWTCLFSCYYGLMAEKNRALNALDSSALFSGSPVLFRTRLAAQMRFKQQFEAEPCLNRWRGVHKADEYLFFNRYLLQEAVHEVPCLVVFQDTPDATVQADRRSIAEFLSEYLQMTRNLWRLSRVMIRQRERNQYPWAFLLTHLSSFASFTLIYEILFVLLVHFTIHLDDDEWIAWGTFGSLLLIFQTVVGAQIVRRITANNYGYDDCSTGTLLALLLVQLAYYVLEVLRLVALATAWKADVELISEADIKARAGDPEALRYHVNGAEEARTEINEPPWISRCMELERPRRELRPLPDFPLFVIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKB5</accession>
    <name>X0CKB5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658372">
        <property type="protein sequence ID" value="EXK91718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKB5"/>
    <dbReference type="HOGENOM" id="CLU_2197085_0_0_1"/>
    <dbReference type="OrthoDB" id="5416097at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK91718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12193" checksum="0C63005C168E3697" modified="2014-05-14" version="1">MDIDETTSFEVKSESTLELQVIEPPSSTESESEYTDELQAIEPPRIDKHKIDFAEQTKFLARNGNACVVTGAMNPNAYHIAPFTWNDTQEHIDRTFDLGPNQTFMVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>X0CKD4</accession>
    <name>X0CKD4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FOQG_04652</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CKD4"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006466_0_0_1"/>
    <dbReference type="OrthoDB" id="1405595at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="18"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="76"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="519"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="889"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXK94646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1003" mass="112764" checksum="7E53C5AE764B5948" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>X0CLK4</accession>
    <name>X0CLK4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_03925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CLK4"/>
    <dbReference type="HOGENOM" id="CLU_217717_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3459" checksum="22E4F03EF744C39F" modified="2014-05-14" version="1">MVLVVSVLVLEAGPLDDARNLSILEAFFLSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0CN70</accession>
    <name>X0CN70_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_03138</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK95895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CN70"/>
    <dbReference type="HOGENOM" id="CLU_034568_0_0_1"/>
    <dbReference type="OrthoDB" id="3231000at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK95895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="529" mass="60834" checksum="1EC5750D45C0AA0E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQN0</accession>
    <name>X0CQN0_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xaa-Pro dipeptidyl-peptidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_11057</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658393">
        <property type="protein sequence ID" value="EXK84812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQN0"/>
    <dbReference type="eggNOG" id="ENOG502RPGM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015590_3_0_1"/>
    <dbReference type="OrthoDB" id="2578740at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF10">
        <property type="entry name" value="COCE_NOND FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="3">
        <location>
            <begin position="323"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="10"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK84812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="588" mass="66626" checksum="0D43686769D5EC3A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>X0CQX2</accession>
    <name>X0CQX2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Iron-sulfur clusters transporter ATM1, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Iron-sulfur clusters transporter atm1, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FOQG_05400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">54005</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">54005</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658369">
        <property type="protein sequence ID" value="EXK93254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CQX2"/>
    <dbReference type="eggNOG" id="KOG0057">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_4_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140466">
        <property type="term" value="P:iron-sulfur cluster export from the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18582">
        <property type="entry name" value="ABC_6TM_ATM1_ABCB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03253">
        <property type="entry name" value="ABCC_ATM1_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000004">
        <property type="entry name" value="ATP-binding cassette sub-family B member 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000186">
        <property type="entry name" value="ATP-binding cassette sub-family B member 7, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF402">
        <property type="entry name" value="IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="17">
        <location>
            <begin position="116"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="16">
        <location>
            <begin position="439"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="42"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="679"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="685"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00039906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00040792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EXK93254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="700" mass="77769" checksum="F00A1095BB89698A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CR80</accession>
    <name>X0CR80_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_05011</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658368">
        <property type="protein sequence ID" value="EXK93813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CR80"/>
    <dbReference type="HOGENOM" id="CLU_1570718_0_0_1"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF6">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="6">
        <location>
            <begin position="4"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="6">
        <location>
            <begin position="86"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK93813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="170" mass="18857" checksum="C69C39C2B9713037" modified="2014-05-14" version="1">MVGLVNNCMAEMAVQHPVSGAFIRMAGHWVDEAFGFMVGWNFFLYEALRVPFEVPASNVVLKFWRDDIPVAAVVAACIVLCGVINAPKFLLKCTSLGLPVYCLGIVMPFPFPAFLAVSNDSVVVLTWLTNVITAAEIIDHIVISITYIFFYRAYKAQGIDRPTPPYCGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CRR9</accession>
    <name>X0CRR9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_10821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658391">
        <property type="protein sequence ID" value="EXK85167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CRR9"/>
    <dbReference type="HOGENOM" id="CLU_054962_1_0_1"/>
    <dbReference type="OrthoDB" id="536211at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07739">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050855">
        <property type="entry name" value="NDM-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42951">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42951:SF14">
        <property type="entry name" value="METALLO-BETA-LACTAMASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK85167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="280" mass="30812" checksum="51DBFC0EB4073EF9" modified="2014-05-14" version="1">MVLQYSVFFSNRDSATRSGPAGHDHLRWVPTSSTLIYGDNDAVLVDAQLTSQASNELLDWVVESGKNITHIYVTHAHGDHFFGSAPILERFPQAVLVATPEVVARMKLETAPARLAGLWEKLFPGQIPPTLRVAEPLEQAYIELEGERLVVVRTGHTDTDDTTTLWVPSIKLAVTGDAVYANTHPYLGESGTAAKRREWIEALDAIASLDPSHVVGGHSDPSRPFGVEAIGDTKTYLEVFERLSSETKTAEELYARMMEIYPDRLNPGSLWAGAILVHKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0CSW8</accession>
    <name>X0CSW8_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_02487</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CSW8"/>
    <dbReference type="eggNOG" id="KOG1268">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042555_4_1_1"/>
    <dbReference type="OrthoDB" id="14446at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061672">
        <property type="term" value="C:glutathione hydrolase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008242">
        <property type="term" value="F:omega peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01908">
        <property type="entry name" value="YafJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000045">
        <property type="entry name" value="Glutamine amidotransferase DUG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052373">
        <property type="entry name" value="Gamma-glu_amide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187:SF1">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="3">
        <location>
            <begin position="2"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="328"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="394"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXK97216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="479" mass="53468" checksum="4D53D02FC34BABBA" modified="2014-05-14" version="1">MCRFLVYKGSDEILLSKLILDPTHSILKQSFDSRLRLDTRRGQNNADGFGIGFYTDPKLGSAPCLFTSTIPAWNCTNLQRIASKTASRLIFGHVRATTEGSLSEDNCHPFTHGSLMWMHNGGLGGWKYIKRRLGERLADKWYLGVKGGTDSEWAFALFLDTLERLGHDPSACPETGFGPTILREAMKRTIAQINEMTDAIPESILQNEDVDTRSLLNFAVTDGHSVICTRYISSSKDEAASLYYSSGTQWTTRTQSASDKQYQMERKDRGADIVLVASEPLTFERENWVNVPTNSILTIHRQTVMVHPIIDKYYERDPHHVRSSAFVQAKGLTSNEKNRSDVASPAGVDRQQQELDGYRKMMTGTLNFGPPRSLSPDMCRQTRKVAPVRESIPVPQPQAQPPPAQTTPPSEQGNKPAPAQGNIKVKRRSVQLLDGNQGQSSNDYDQISDTEEPTRADVHNPRKLSRYFPELTLASHAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTT2</accession>
    <name>X0CTT2_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTT2"/>
    <dbReference type="HOGENOM" id="CLU_767353_0_0_1"/>
    <dbReference type="OrthoDB" id="5038024at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="361" mass="41420" checksum="DE04FA6390B733F3" modified="2014-05-14" version="1">MDSLYEDVFESYGRESESEPERFEETLDSSCTPVKRQCAKCRKLGRRCFRYRLKLALGEESEEPTKSALELAVASQASPRNDESEDTILEPIPKPVEIIRSQKNVQNGETPSAIPWWSNSKSQLHDYPQTPPKYRTASFHTSSHETHFYDGATTRNTRHYESNISSSGISTQSRWKALAPEPASYHRSDAEIEVVKINRSWHFVSTKCHVKRNENGGVTHSHEHRHWAEPFKELPHCKGCRSLEEKTSNIPEHVKFYNATITFIERFPWRGYTHAVWVALAETPPSMPGSVTRSTIQYKVSCTVYRDQLYGPGRLVNSVWKPDEPVIPLESFCSSIYDFGRSAVHWVQERITGVKHSDETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0CTX4</accession>
    <name>X0CTX4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Altered inheritance of mitochondria protein 24, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_02746</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AIM24 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CTX4"/>
    <dbReference type="eggNOG" id="ENOG502RXC5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046558_0_0_1"/>
    <dbReference type="OrthoDB" id="5295771at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959:SF2">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK97611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="390" mass="42781" checksum="AF66AF974E2E1470" modified="2014-05-14" version="1">MRGQLPLTRAARGLRLRALPSYTCTQCRSIQISAAPSTEAPKVGADAFGALETRDPADARFEVLGSPYSLLSVTLSASQKLYTRRGTLVAVAGKPENAQSTLSILNPITRAFLGVPFLYQRISATTPITALISTKSPTTTFTVLHLDGTTDWMISQRNALLAWTGHTLAPSARIQSSLTLAHWGNTLLTGRGLAALSAPGQIYELTLKEGEEFVAHPGSVVAYSISRYPPQPFRFKSNSLRLQVPSLSRWISEPEWVKTVRNSEVWKYLARALYSMRTATRRTIWGDRLFLQFHGPTKILMSSRGVRASDVLTNKQVNEIADAQPGVLAEALDLKNKPKLTDGAETKPAPVKAVEPEVEDKSVTGIHVATVEKDGKVKFEDNKDLKEFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0CU91</accession>
    <name>X0CU91_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_04509</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658367">
        <property type="protein sequence ID" value="EXK94444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CU91"/>
    <dbReference type="eggNOG" id="KOG2208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003293_0_0_1"/>
    <dbReference type="OrthoDB" id="10027144at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22448">
        <property type="entry name" value="KH-I_ScSCP160_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22449">
        <property type="entry name" value="KH-I_ScSCP160_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22450">
        <property type="entry name" value="KH-I_ScSCP160_rpt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22408">
        <property type="entry name" value="KH-I_Vigilin_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02394">
        <property type="entry name" value="KH-I_Vigilin_rpt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054548">
        <property type="entry name" value="SCP160-like_KH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627:SF31">
        <property type="entry name" value="DODECA-SATELLITE-BINDING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627">
        <property type="entry name" value="SCP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22952">
        <property type="entry name" value="KH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="200"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="282"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="379"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="532"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="698"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="765"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="859"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="932"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1013"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1082"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1195"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="807"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK94444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1272" mass="138384" checksum="2617483EA22B57F4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CV60</accession>
    <name>X0CV60_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_09649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658385">
        <property type="protein sequence ID" value="EXK86377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CV60"/>
    <dbReference type="HOGENOM" id="CLU_604174_0_0_1"/>
    <dbReference type="OrthoDB" id="5087721at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK86377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="371" mass="40839" checksum="5D4D6971192BACFD" modified="2014-05-14" version="1">MTALGNIQKTLDSLQDKQQQQTNIAIIGGSLTSIKTWQTRYATATKFNNTSEINTLINEFNENAPTYITKIFNVLNGQGLGPGTAPLLKSWHAASYAKMYTPVNGQYAFTLRNYLDDYNSIVSWVISMAALAAPTMSASYFQGEADQYTSDFQTNATAVLGVAYDQFAPFVKKFKPNYTDVGPNLNQWFRMWYNETHVKNYIGWRGSSRNVEDDQNYGVPQFNAGNNEYQLYPLACDDDEVHIYNCEDTGASSNLGDMSGVNSAGLTTTADSQYWCSGVTFNQAIFNVLPLSSEDMGGNTAPGFLLLVANPPTDKQHGIFDPQFPSTVSSKQKYCILRDDGLDQTSWVQTQNSASTAPGDNSEVPSPNPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0CW34</accession>
    <name>X0CW34_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_04088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CW34"/>
    <dbReference type="eggNOG" id="KOG1716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049471_1_0_1"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990444">
        <property type="term" value="F:F-box domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062026">
        <property type="term" value="P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070372">
        <property type="term" value="P:regulation of ERK1 and ERK2 cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052449">
        <property type="entry name" value="STYX-Interacting_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588">
        <property type="entry name" value="SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588:SF1">
        <property type="entry name" value="SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK95523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="317" mass="35290" checksum="D6B835EF9B8CB9A0" modified="2014-05-14" version="1">MESSSGPHPSFANNAVPSAPYVRRAPSPPFIHIPPTGHCGVSAAPILLPSYEQVDSSQLTAHDVKIITQNMQQIATDRAADWSYEQRRDAQKLVDFLYLGPNSIAKDIKWLQEEGITMIAVARDARMAGVKLMSVEKAAKTLNIEVQYVDLEGNNKLISSFPDIIRLINDHLLSVYHSQAKGRNKNGELLVDPSSFRRGKVLITCETGNDRSAAIAAAYIMAVFGKDMITAVQFISIQRFCCAFDEDIKRKLQCWEDILRARSQVAMEQAVLPNATHTKRHIDDLMDTSEDPNDKGEFALDHDRFNGRGSFAPFVDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXL9</accession>
    <name>X0CXL9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Porphobilinogen deaminase</fullName>
            <ecNumber evidence="5">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Hydroxymethylbilane synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FOQG_04164</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HMBS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="5"/>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXL9"/>
    <dbReference type="eggNOG" id="KOG2892">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019704_0_2_1"/>
    <dbReference type="OrthoDB" id="564646at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13645">
        <property type="entry name" value="PBP2_HuPBGD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.40:FF:000002">
        <property type="entry name" value="Porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000005">
        <property type="entry name" value="Porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000086">
        <property type="entry name" value="Probable porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="entry name" value="Porphobilinogen deaminase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557:SF0">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobilinogen deaminase N-terminal" evidence="13">
        <location>
            <begin position="10"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobilinogen deaminase C-terminal" evidence="14">
        <location>
            <begin position="240"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXK95614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="334" mass="36824" checksum="30E34BA002983D14" modified="2014-05-14" version="1">MAESQSKGVVNVGTRKSPLALAQTQIVVDALKKNFPDHEFNIHSMTTTGDRDQNTALYNFGGKGLWTSQLEEKLVNKELDIVVHSLKDMPTVLPEGCVLGCVTSREDPRDTLVIKKELQDKHGWKTLADLPDGSIIGTSSVRRIAQLIRRYPTLKFKDHRGNIQTRLRKLEEDPDLTGIILAAAGLQRMDLGDRITQFLESDNGGILHAVGQGALGVECRADDEEVIRLLKTIENEQTALACEAERALMRALEGGCSVPIGVETKWVDDKLHMKATVVNLRGDHGVDSDITEPVKTHEEADKFGRKLANALVERGGGSILDEITRLRQVPETVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXN1</accession>
    <name>X0CXN1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658383">
        <property type="protein sequence ID" value="EXK87202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXN1"/>
    <dbReference type="eggNOG" id="ENOG502TKEQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1065779_0_0_1"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="41"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="261" mass="29475" checksum="0CBF63DC8CDAB8D0" modified="2014-05-14" version="1">MAPPRKKPRTRAGPKDDPADEQSAGILADFRTSWLLKNDEQLVELKVKGETFQVAKNVLTKNSEYFESCLNGRFAEAKKGGVEFNDEDIEPRYLALYIGVAYSHSSIVPHAHPRPAQSPEAAPIKTPMRDYVEVYKLCDRFISPSMGEFIARCIDVAIGNGHRALYRTEADQGTQKLLMRDFADGYEALNMQHSSQAELGDRMITYFCEGVSYKAWIETMEELRDRPKFIGHVSRGFATKLQELQVGRKLKRKEWAGPGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0CXS4</accession>
    <name>X0CXS4_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_09094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CXS4"/>
    <dbReference type="HOGENOM" id="CLU_012207_0_0_1"/>
    <dbReference type="OrthoDB" id="3692311at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004937304" evidence="2">
        <location>
            <begin position="25"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK87252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="550" mass="60826" checksum="36BA432E94141E00" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0CY44</accession>
    <name>X0CY44_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CY44"/>
    <dbReference type="eggNOG" id="ENOG502SW30">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118191_0_0_1"/>
    <dbReference type="OrthoDB" id="4158189at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="164" mass="17348" checksum="B64A2E49C099674D" modified="2014-05-14" version="1">MCGPEYTNRPRGGALAALNPPINSISSNICGDLAFHTPGSPSSSRATHARLTPSEECSMKGFSDLYVVIHSSGDLTRNASECGLFRQFSLQTPPTSREYVELPLQGPLSLEVGGDGIIGRRVSVYSRLASGQDRIVAEGIVGFNFMSQASPEETSCPSSPSPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>X0CYD9</accession>
    <name>X0CYD9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_09278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979324">
        <property type="protein sequence ID" value="EXK87492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CYD9"/>
    <dbReference type="HOGENOM" id="CLU_3392336_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK87492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3561" checksum="707B01CF62D145D6" modified="2014-05-14" version="1">MADDDLSRYRPLRHLTDAGAGGMFPGVWEVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZ98</accession>
    <name>X0CZ98_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Solute carrier family 25, member 46</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_02070</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK96628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZ98"/>
    <dbReference type="HOGENOM" id="CLU_015166_16_2_1"/>
    <dbReference type="OrthoDB" id="409586at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF12">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="2"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="99"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="199"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK96628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="280" mass="30583" checksum="72C480812938EC86" modified="2014-05-14" version="1">MADTVRDIVAGAMGGAAQVLIGQPFDIVKVRLQAYGGDALDVTRKIWSLEGPRSFYKGTLPPLLGVGACVSIQFGAFHFFSEQFDNVNKQQHSNHEGSLSLGQVYLSGGLAGVTNSVISGPIEHIRIRLQTQPHGEKKLYSGVSDCVRKIWQHQGISGIYRGQAVTIPREFHGYGVWFAAYEGLVQHVARMEGKSRSEIESWKFAVCGGLAGEFLWLLSHPLDVIKSKMQSDGFGHDQEYKTMREAIRQTWRMGGVSGLFEGIGPALLRAMPVSAGTFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0CZQ7</accession>
    <name>X0CZQ7_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_03411</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="2"/>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0CZQ7"/>
    <dbReference type="HOGENOM" id="CLU_006406_6_0_1"/>
    <dbReference type="OrthoDB" id="68056at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="entry name" value="Arginyl tRNA synthetase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956:SF11">
        <property type="entry name" value="ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="ARGINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DALR anticodon binding" evidence="10">
        <location>
            <begin position="518"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK96339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="635" mass="71786" checksum="AD602382282937AB" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0D149</accession>
    <name>X0D149_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Riboflavin kinase</fullName>
            <ecNumber evidence="4">2.7.1.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Flavin mononucleotide kinase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_08245</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>riboflavin + ATP = FMN + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="4"/>
    <dbReference type="EMBL" id="JH658380">
        <property type="protein sequence ID" value="EXK88412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D149"/>
    <dbReference type="eggNOG" id="ENOG502SKSA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022880_1_0_1"/>
    <dbReference type="OrthoDB" id="276388at2759"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749:SF6">
        <property type="entry name" value="RIBOFLAVIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Riboflavin kinase" evidence="15">
        <location>
            <begin position="415"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="95"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXK88412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="623" mass="67663" checksum="7CD4055862AED3A2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>X0D578</accession>
    <name>X0D578_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Vacuolar amino acid transporter YPQ3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FOQG_01517</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-histidine(out) + L-arginine(in) = L-histidine(in) + L-arginine(out)</text>
            <dbReference type="Rhea" id="RHEA:71063"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the laat-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D578"/>
    <dbReference type="eggNOG" id="KOG2913">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019699_0_0_1"/>
    <dbReference type="OrthoDB" id="8048523at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034486">
        <property type="term" value="P:vacuolar transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000009">
        <property type="entry name" value="PQ loop repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000012">
        <property type="entry name" value="Vacuolar membrane PQ loop repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="113"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXK98698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="34901" checksum="89C2B082620F7F9D" modified="2014-05-14" version="1">MPLLASTSIAAAAHALPVTLALSGIFGSISLTSWICLLLPQLFANYKAKSADGLSMAFLVVWLLGDITNLIGALFTHLAPTAIALAGYFCIADIVLIGQAVYYNALNARRASRAGERRSSDPTEESPLINGSRRRSSSFGLPGSQRRHATHTESSMDPLRKIVTGEDETPDSKPWLHNTLSLLAVYVIGFAGWFVSYKVGAWESGDPGTPDAPEEAQSPMELAGLILGYISAALYLCARIPQIIKNHREKSCEGLALLFFMLSMSGNLTYGISLVAYSQDKKYLLNALPWLLGSLGTIAEDLIIFVQFRIYSNDERESAIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5C5</accession>
    <name>X0D5C5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_01262</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5C5"/>
    <dbReference type="eggNOG" id="ENOG502SNUJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5424793at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK98319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="636" mass="72176" checksum="78FE7B699DDA9545" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0D5Y9</accession>
    <name>X0D5Y9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_07466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658376">
        <property type="protein sequence ID" value="EXK90062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D5Y9"/>
    <dbReference type="HOGENOM" id="CLU_017046_0_0_1"/>
    <dbReference type="OrthoDB" id="8964853at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040112">
        <property type="entry name" value="WetA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22934">
        <property type="entry name" value="PROTEIN ESC1/WETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22934:SF23">
        <property type="entry name" value="ZF-C3H1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="336"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK90062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="492" mass="53716" checksum="F5CEF4F98A812392" modified="2014-05-14" version="1">MDVHNQPRLPPPKPVGLNNILNNDNAPVSIVNGPPHMRDSGFYSNADASSKHTSAASFNVNGLSPSGSGYQSSSHEKTPSPIASNMIPNGLVSPSTTNMSVAAMVSPSTPSSLDARRDRPTSIESNGLGPNPGPTMGDTLAPGMAAMRRESVDSRINQNFGDLRLGGSPYASHNHSTTSIQNTLHNQRNPHHLSVHRISNGYQPSAERNPEGKTVKTAPAITGPATGHIARAAEPTKGQAWAFPEEEIQRVGGAPTYTDSRRSSITESIASSQFTTESRLPPGQMRLNESEYSRMSNASDFPPVHHHSMQHKQLSDLQAEEGNGSTGSQPYSRTPELRVSHKLAERKRRTEMKELFDQLRDLMPQERGSKASKWEILTKAIAEHQKQQDIIRALQDHYKSNTAENEMLRRDVHALRMENQQLRSELNSSSSRPPLSSAATPAPQAGTYQADPYPNPNRPELPPLRSLRNSIPNGPDSMTGVQYDSPRTNGYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>X0D768</accession>
    <name>X0D768_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription elongation factor Eaf N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_01687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D768"/>
    <dbReference type="eggNOG" id="ENOG502SEGQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041956_0_0_1"/>
    <dbReference type="OrthoDB" id="125903at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019194">
        <property type="entry name" value="Tscrpt_elong_fac_Eaf_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09816">
        <property type="entry name" value="EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription elongation factor Eaf N-terminal" evidence="2">
        <location>
            <begin position="15"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK98989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="339" mass="37333" checksum="88CE4B7CCCEFF8BC" modified="2014-05-14" version="1">MAAAGLIDPTKTGNYPVILGDALLGKTSNEIFTGIKYNHKPTLSSDSAPNLARIKPSIPGKTASYDLTYTDNDAKYAFTGTRNKDSGQYVLYFDPSREAFILDLVDSTFNMNVTRLPGNADADSLRRQYPHIDSASNGASKTNIKAEKSASDKSNAKTRAKSTTQKRDVKRKPEKKQAPKNIELSLPVPQSNEQSKPAEPKKRTPAPEEEDEDEDDDDGGLLVEYPGADTNTARRTDFSPAFPSVRRFDEFMDQRESEGDDADGEDDDDPDFEFKLPSPVNNRSQYETGPDPMDVDGGEEGEEGPEVDLAKELEDAFENLENSQQESPDGDESEISEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8E1</accession>
    <name>X0D8E1_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_06999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2012-05" db="EMBL/GenBank/DDBJ databases">
            <title>Annotation of the Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genomics Platform"/>
                <person name="Ma L.-J."/>
                <person name="Corby-Kistler H."/>
                <person name="Broz K."/>
                <person name="Gale L.R."/>
                <person name="Jonkers W."/>
                <person name="O'Donnell K."/>
                <person name="Ploetz R."/>
                <person name="Steinberg C."/>
                <person name="Schwartz D.C."/>
                <person name="VanEtten H."/>
                <person name="Zhou S."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Chapman S.B."/>
                <person name="Gainer-Dewar J."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Hansen M."/>
                <person name="Howarth C."/>
                <person name="Imamovic A."/>
                <person name="Ireland A."/>
                <person name="Larimer J."/>
                <person name="McCowan C."/>
                <person name="Murphy C."/>
                <person name="Pearson M."/>
                <person name="Poon T.W."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502RA0T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003025_0_0_1"/>
    <dbReference type="OrthoDB" id="5382102at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42105">
        <property type="entry name" value="DIM2-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42105:SF1">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="759"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="854"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1268"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1538"/>
            <end position="1701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="537"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="773"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="880"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="941"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="969"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1000"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1269"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1293"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1305"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1386"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1432"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1552"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1632"/>
            <end position="1653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK90887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="1701" mass="185039" checksum="66CEB3FEEDACBD0F" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>X0D8E5</accession>
    <name>X0D8E5_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="9">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FOQG_07003</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Lipid-anchor</topology>
            <topology evidence="1 9">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JH658374">
        <property type="protein sequence ID" value="EXK90892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D8E5"/>
    <dbReference type="eggNOG" id="ENOG502QRZZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021855_1_0_1"/>
    <dbReference type="OrthoDB" id="421038at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042124">
        <property type="term" value="F:1,3-beta-glucanosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071970">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000032">
        <property type="entry name" value="1,3-beta-glucanosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF5">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 9" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005152151" description="1,3-beta-glucanosyltransferase" evidence="9">
        <location>
            <begin position="17"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="376"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="393"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXK90892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="448" mass="48384" checksum="7BCD3E50429DA69C" modified="2014-05-14" version="1">MKTVAFLSALAAVASATPTLKEPPSKRASLPAVSVSGNAFWTGKDRFYLRGIDYQPGGASANEDPLADPDVCKRDIKYFKELGVNVIRVYAVDNKADHDECMSALDAAGIYLVLDVNNPKYSINRAKPGPSYNAAYIQSVFATVEMFAKYDNTLAFFSGNEVMNDEKDTDKSAPYVKAITRDMRNYIKARKLRQVPVGYSAADVASNRMQTAHYMNCGSEEVRSDFFAFNDYSWCNSDFKTSGWDVKVKNFTNYGIPIFLSEYGCIENRPRKFEEIEPMMDSQMSSVYSGGLMYEYSLEDNDYGIVTIKNGKVTTEKEFDLFKSALSKYPMPTGTGGAAKASHGVACPTSESVWQVDPSYLPEMPSEAEKYMKDGAGKGPGINGKGSHFDTDSGTATASVAMGSSTSTGSASASGDDGDDSGAASLGFGALYVSAAATLFTLVGTLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>X0D9T1</accession>
    <name>X0D9T1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Arp2/3 complex 34 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_00528</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0D9T1"/>
    <dbReference type="eggNOG" id="KOG2826">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059439_1_0_1"/>
    <dbReference type="OrthoDB" id="148331at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000003">
        <property type="entry name" value="Arp2/3 complex 34 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000005">
        <property type="entry name" value="Arp2/3 complex 34 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007188">
        <property type="entry name" value="ARPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058">
        <property type="entry name" value="ARP2/3 COMPLEX 34 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04045">
        <property type="entry name" value="P34-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXL00309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="319" mass="36635" checksum="44E7FDCAE5580DFA" modified="2014-05-14" version="1">MLLLDYQNVLIQSVLTERFSGAPPASIDQTVSDFDGVTFHISTPESKTQILLSIQIRCFPDLVKYGAEEVLQREYGDYMTSVEPGFDFSVLVDLENLPESKEERNELALKFALLKRNAMAAPFEQAYKEHYALKEEASKFTSEEAPQGVREGGEVKAIHYREEEAIYVKASHDRVTVIFSTVFREETDRVFGKVFIQEFVDARRRAIQNAPQVLFRNDAPLELQGVPGVQDTGSGDIGYVTFVLFPRHLTPQRMTEVISHIQTFRDYFHYHIKASKAYIHSRMRKRTADFLQVLRRARPENEEKERKTASGRTFKVQGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>X0DBK3</accession>
    <name>X0DBK3_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FOQG_05947</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658371">
        <property type="protein sequence ID" value="EXK91952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DBK3"/>
    <dbReference type="eggNOG" id="KOG0265">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_2_1"/>
    <dbReference type="OrthoDB" id="1068471at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052234">
        <property type="entry name" value="U5_snRNP_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006:SF1">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="101"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="143"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="192"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="227"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="277"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="319"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXK91952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="354" mass="38368" checksum="CABFDB2118845D50" modified="2014-05-14" version="1">MSAEKRPADGDPSSSQSLVKRQNVNSSTGALARLNASSNALVQSAPRTSGLQAPVMELSGHSGEIFAAKFDPTGNLIASGGMDRSLMLWRTYGDCENYGILNGHRGAILDLQWSRDSEILYSASADMHLASWDLTSGTRIRRYVGHEEVINTVGISRRGEEILVSGSDDSTIGIWDPRSKNAVDYIQTEFPITAIAVSEAGNEIYAGGIDNDIRVWDLRKKSVIYSMLGHSDTITSLRVSPDSQSLVSYAMDSTVRTWDIRPFAPTERHIRTFDGATMGMEKNLLGASWDSEGKRIAAASGDGTVMVWSSETGKLAYKLPGHKGTVNCAEFSPNKEPILLSASSDRTMLLGELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>X0DMB7</accession>
    <name>X0DMB7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_04082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658366">
        <property type="protein sequence ID" value="EXK95517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DMB7"/>
    <dbReference type="eggNOG" id="ENOG502RP82">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019656_0_0_1"/>
    <dbReference type="OrthoDB" id="5325276at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF12">
        <property type="entry name" value="AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK95517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="750" mass="82615" checksum="41020D82876C8A2E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>X0DPA7</accession>
    <name>X0DPA7_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_03281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DPA7"/>
    <dbReference type="eggNOG" id="ENOG502RNNK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_631758_0_0_1"/>
    <dbReference type="OrthoDB" id="5204927at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK96147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="433" mass="47311" checksum="9C3398FDAC10A2C4" modified="2014-05-14" version="1">MTTTMLYTTGISMEEPSHRFSPTTVAPGKPRHRPKALQIQPLDPNELSAKLNDISVEQEGQPRRPVHTEDSLRPPLSATSMGAPSPRTIQATHASPSIPTTVSSRVFRKEKIDDKLSSPLSAKPPRRGSFFDAFRFRGSNYTDELQKQTEEEGVQKPARYKHVPQVAAQQFARTTTVEPLTQKASPKGMRPAPGPYSVNNGTISLQEYNRQYRRAQSLCSGRPTSASNVARMGGTELDKVSAQRKRQTARSSMLWNVNGPELSRRMSTGNMQPLPQARRDSIGTGVGGFQGNVASSARRGSASSSGFSDASSPFVRESGPATPFKQEFGINTSPNRRGSETSAATSGSRRGSFVNVPNPQHAAEIHRVDWSQSDQPVKGRRDSKWGGLKHRKTSLSQQKPNAEDQGPSFTKTGSQSSVSPKSPKSGFLKRFMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DPH9</accession>
    <name>X0DPH9_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_03313</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658365">
        <property type="protein sequence ID" value="EXK96192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DPH9"/>
    <dbReference type="eggNOG" id="KOG1728">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073626_0_1_1"/>
    <dbReference type="OrthoDB" id="10254436at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.1000:FF:000001">
        <property type="entry name" value="40S ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028333">
        <property type="entry name" value="Ribosomal_uS17_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_uS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032440">
        <property type="entry name" value="Ribosomal_uS17_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03630">
        <property type="entry name" value="uS17_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF9">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16205">
        <property type="entry name" value="Ribosomal_S17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS17 N-terminal" evidence="5">
        <location>
            <begin position="8"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK96192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="161" mass="18450" checksum="2C8256EAC97376EC" modified="2014-05-14" version="1">MATELTVQSERAFQKQPHIFQNSKTKTKSTRPGKGGRRWYKDVGLGFRTPKAAIEGSYIDKKCPFTGLVSIRGRILTGTVVSTKMHRTIIIRREYLHFIPKYSRYEKRHKNVAAHVSPAFRVEEGDQVTVGQCRPLSKTVRFNVLRVLPRTGKAVKKFSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0DU23</accession>
    <name>X0DU23_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein SGT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_02813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DU23"/>
    <dbReference type="eggNOG" id="KOG2406">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006241_2_0_1"/>
    <dbReference type="OrthoDB" id="27237at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010770">
        <property type="entry name" value="Ecd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060:SF0">
        <property type="entry name" value="PROTEIN ECDYSONELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060">
        <property type="entry name" value="SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07093">
        <property type="entry name" value="SGT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK97727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="633" mass="71908" checksum="5F315E4FDE238C99" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>X0DUL4</accession>
    <name>X0DUL4_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_02947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658364">
        <property type="protein sequence ID" value="EXK97922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DUL4"/>
    <dbReference type="eggNOG" id="KOG1430">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_8_1"/>
    <dbReference type="OrthoDB" id="10058185at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK97922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="367" mass="40843" checksum="64E03461762C9B96" modified="2014-05-14" version="1">MSDIRKPSIPLIKSSLVVGGCGFLGFHLVRHLMQDDESGEVYVLDRDVSRNRQENVSYVKGDISDREFLRGVINEIRPTVIFHCASPVAALPMNREGEFYTTNVKGTEVLLTAAAACDAVQAFVFTSSVDAYANPPHTNADETYPLWSPNDKSNEYNRTKAIGDHLVRGANGPRLRTVTLRPGHAYGERHVQGMVEVLDMCKNKKLVQIGDGKNLMEVVSGENNAIAHVLAAKALLDPSRASGKVDGEAFNVSDGAPVPFWHHTGVIWKTARGEDVFKDVIVLPAWVMIVAVFLAEWTFWILTLNTAKPPVELRRVSLEYCVYTHTHSIEKARKRLSFNPVSDHDAVVAQSARWMLKYRESMKQKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0DXF3</accession>
    <name>X0DXF3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nicotinamide N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_01599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658363">
        <property type="protein sequence ID" value="EXK98847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0DXF3"/>
    <dbReference type="eggNOG" id="ENOG502RXJG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056749_0_0_1"/>
    <dbReference type="OrthoDB" id="2106152at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40470">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G15850)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40470:SF1">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G15850)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK98847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="33276" checksum="137F0505046F3CAC" modified="2014-05-14" version="1">MSTSQYLQDLNRDGFVVIKSIVSKDKLDALREVSSKATQLAREGQWPYVRTVGKQFPPWDASQAREHGIWGVQHLMNPDLPGHELFTELYFSEAILGIVKQLLQCQDEHLVMELFNMLVRPERDFELRWHRDDIPGEASEDEEMERLGKHAYHAQYNFALWDDDSLIVVPGSHKRARTSTERNADPFAKFLPDQLIVKLQPGDIVFYNNNILHRGAYSSSKERMTLHGSVGHVQGSTLRARNVLQHGIGNWVDKCAFESLPEEDRHRADGMRQRLIQLGSESGQVGYSLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>X0E1B1</accession>
    <name>X0E1B1_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">leucine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FOQG_00428</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JH658362">
        <property type="protein sequence ID" value="EXL00133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0E1B1"/>
    <dbReference type="eggNOG" id="KOG0435">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004427_0_0_1"/>
    <dbReference type="OrthoDB" id="15954at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000002">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000003">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000034">
        <property type="entry name" value="Leucine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000100">
        <property type="entry name" value="probable leucine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740:SF2">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="14">
        <location>
            <begin position="86"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Leucyl-tRNA synthetase editing" evidence="15">
        <location>
            <begin position="272"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="479"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="670"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="13">
        <location>
            <begin position="783"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXL00133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="957" mass="107033" checksum="67922EB02852D45E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1B3</accession>
    <name>X0B1B3_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_19331</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979720">
        <property type="protein sequence ID" value="EXK75905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1B3"/>
    <dbReference type="HOGENOM" id="CLU_912285_0_0_1"/>
    <dbReference type="OrthoDB" id="5098218at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="101"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK75905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="305" mass="33975" checksum="CA4A1CA87DB67A44" modified="2014-05-14" version="1">MDSKIWMPYVTDDYIPKSEYRMNTEVEQTDKAITVRASCQGEFMTKRDLDRTLKDFSQAFCDIIQHPLRCVTIFPDELQSLPLSFGSSSDSAVSVISTPGPSHEPVIRGILSKVSKVSIEAIQPDTSIFSIGLDSLSAIRIASMCRAAGFKAGVSDILQGNTLRGICLRIHDMPQENTSKQSLIKDYSSVKKYVIVQFGMKPNAIEKILPCLSGQMYHLASWLQTGRTPFEPAWPFSCSERINVETMKDAWFLLRDNNPILRTCFYDISPSQVVQIVLSECGRNDGIFQVIASAESLENLAIAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>X0B1F9</accession>
    <name>X0B1F9_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">adenine phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FOQG_19646</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">54005</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5"/>
    <dbReference type="EMBL" id="JH658798">
        <property type="protein sequence ID" value="EXK75586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B1F9"/>
    <dbReference type="HOGENOM" id="CLU_019466_0_0_1"/>
    <dbReference type="OrthoDB" id="363185at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002055">
        <property type="term" value="F:adenine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050054">
        <property type="entry name" value="UPRTase/APRTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315:SF3">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="154"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXK75586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="322" mass="35295" checksum="8CE57779C19EE45D" modified="2014-05-14" version="1">MRQQPRLPEKHFLNVVSDAADMDVLVITGMRDEAPTATLSHLVSNSRLLDIRVTASGKTRQARRKCQVNDNDRHNHDCNNDNRGSNGSNCKSNSSTLDYRHSLVFDNEATGDEVIRRFADQYLLPLLHKDLERLASMVVPVPDFPRPGIEFRHVLNIAQRQGGLALCTSLLRTQFKDDWGKVGAVACCEAGGFVFASALAQQVDVPLALIREAGKLPPPTFSVKKPSSHISCSEPNDLGVKRIEMSQDLIPRGASVVVIDDVLTIGKTLCTVLQLLAEAGISNENISIMVVAEFPIHCGRELLYHRGFGGISIQGLLVLDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2023-02-22" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>X0B275</accession>
    <name>X0B275_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">FOQG_19385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979766">
        <property type="protein sequence ID" value="EXK75851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B275"/>
    <dbReference type="HOGENOM" id="CLU_3392429_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXK75851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="32" mass="3670" checksum="9D14612536DDCFA6" modified="2014-05-14" version="1">MDAANQGSNQGSRELNNEVNRLETELKRRLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>X0B284</accession>
    <name>X0B284_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FOQG_19046</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">54005</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI979571">
        <property type="protein sequence ID" value="EXK76195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B284"/>
    <dbReference type="eggNOG" id="KOG1212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_9_2_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF4">
        <property type="entry name" value="AMIDASE C550.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="5">
        <location>
            <begin position="114"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="3">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="263"/>
            <end position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXK76195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="579" mass="62853" checksum="8F1B7ABCF8E91B43" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>X0B472</accession>
    <name>X0B472_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979430">
        <property type="protein sequence ID" value="EXK76930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B472"/>
    <dbReference type="HOGENOM" id="CLU_1175480_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="269" mass="29968" checksum="E4F5BA1992B16856" modified="2014-05-14" version="1">MNTLQPAPLQRKRGSTTALESDIPKISRLEDKCHELHQTQPVPALSYQRSPPKPSPATPVASTQISVRSGMTLDAAEQQHLFPCVVAVQHPTVCDKKFPLLWQHNCPGKPSEENKHYWQRHYIIDDGAWMAFEDGKWKDVYLPMKVDDRGCREPIPHRNYRKIREAIFPRGLIGTVLLESRLPPPRLPHPAKAQYLWHAPVPVPGSAPDQDRPPPRTAALPGVKGLTSGLGPCTISAAVPDIGLTTRASQGSLYEANQRRRDDLGVYAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>X0B4K2</accession>
    <name>X0B4K2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FOQG_18207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658645">
        <property type="protein sequence ID" value="EXK77070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B4K2"/>
    <dbReference type="HOGENOM" id="CLU_025636_1_0_1"/>
    <dbReference type="OrthoDB" id="3481168at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936697" description="Metallo-beta-lactamase domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="353"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXK77070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="555" mass="61845" checksum="5EAD5343122AAD14" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>X0B555</accession>
    <name>X0B555_FUSOX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FOQG_18382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI979435">
        <property type="protein sequence ID" value="EXK76886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B555"/>
    <dbReference type="HOGENOM" id="CLU_133926_0_0_1"/>
    <dbReference type="OrthoDB" id="10633805at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004936140" evidence="1">
        <location>
            <begin position="19"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXK76886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="170" mass="16336" checksum="05DE933215C00DED" modified="2014-05-14" version="1">MKFSAVIFTIFLAVFSQAQPSEVSSIKPAASSARESASGIVSSAKGTASSVVESVRGSISSAVESKTGNTASAATSTEASTSEHINTAAAASISSNIARISSEIQTAKGAVSSSLHSALESASSALASAKASATASATTSTSTSEAAGAMPTAAVAIGALMGGAAVLVNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>X0B6E2</accession>
    <name>X0B6E2_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FOQG_17619</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">54005</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH658585">
        <property type="protein sequence ID" value="EXK77680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B6E2"/>
    <dbReference type="HOGENOM" id="CLU_021458_2_0_1"/>
    <dbReference type="OrthoDB" id="8907274at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF154">
        <property type="entry name" value="PAP2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G09730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="122"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXK77680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030663"/>
        </source>
    </evidence>
    <sequence length="360" mass="39436" checksum="704BFA506501A326" modified="2014-05-14" version="1">MSGSSLGTLSSGLLGRRFPVRLILSYIFDWIICFAFVGIGGWLDRIAPAKRPFSLIDTSISYPFAEHELVPAYLLFVLAVGVPFAIVVVVSLTLVPGMTVPKGTPKTLIWQRKLWELHVGVLGLVLSLALSWFFTSSMKNLFGKPRPDLLSRCDPDWSNINKYVVGGFKWQSMTGQLVSADICRQTDQYKIDDGFRSYPSGHSSAAAGGLIYASLFMASKFAITLPFILPPAASAAGAASHAAFHSQIRIGPVVDPYELLGTRGLDGSFSSTPTKERAGQDDAKVQSLRRQAAAPPIYLLALGLLPFGVSIFIAGSRWHDRRHHGFDILFGYLMGLTASIFAFRYYHLPIRAAWRIFSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>X0B7U6</accession>
    <name>X0B7U6_FUSOX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7703 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FOQG_17466</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Fusarium oxysporum f. sp. raphani 54005</name>
        <dbReference type="NCBI Taxonomy" id="1089458"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Hypocreales</taxon>
            <taxon>Nectriaceae</taxon>
            <taxon>Fusarium</taxon>
            <taxon>Fusarium oxysporum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2011-11" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Fusarium oxysporum PHW815.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Gale L.R."/>
                <person name="Schwartz D.C."/>
                <person name="Zhou S."/>
                <person name="Corby-Kistler H."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">54005</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH658567">
        <property type="protein sequence ID" value="EXK77841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="X0B7U6"/>
    <dbReference type="eggNOG" id="ENOG502SMNP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045148_0_2_1"/>
    <dbReference type="OrthoDB" id="405906at2759"/>
    <dbReference type="Proteomes" id="UP000030663">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056120">
        <property type="entry name" value="DUF7703"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24802">
        <property type="entry name" value="DUF7703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </l